{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T12:33:11Z","timestamp":1770813191230,"version":"3.50.1"},"reference-count":86,"publisher":"Elsevier BV","issue":"3-5","license":[{"start":{"date-parts":[[1984,12,1]],"date-time":"1984-12-01T00:00:00Z","timestamp":470707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1984,12,1]],"date-time":"1984-12-01T00:00:00Z","timestamp":470707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunobiology"],"published-print":{"date-parts":[[1984,12]]},"DOI":"10.1016\/s0171-2985(84)80117-5","type":"journal-article","created":{"date-parts":[[2011,11,3]],"date-time":"2011-11-03T14:52:45Z","timestamp":1320331965000},"page":"285-300","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":72,"title":["Langerhans Cells: Antigen Presenting Cells of the Epidermis"],"prefix":"10.1016","volume":"168","author":[{"given":"J.W.","family":"Streilein","sequence":"first","affiliation":[]},{"given":"P.R.","family":"Bergstresser","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0171-2985(84)80117-5_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2340\/0001555553112","article-title":"Apposition of mononuclear cells to Langerhans cells in contact allergic reactions","volume":"53","author":"Silberberg","year":"1973","journal-title":"Acta Derm. Venerol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib2","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/1523-1747.ep12482139","article-title":"The role of Langerhans cells in allergic contact hypersensitivity. A review of findings in man and guinea pig","volume":"66","author":"Silberberg","year":"1976","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib3","doi-asserted-by":"crossref","first-page":"570","DOI":"10.4049\/jimmunol.120.2.570","article-title":"Detection of Ia antigens on Langerhans cells in guinea pig skin","volume":"120","author":"Stingl","year":"1978","journal-title":"J. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib4","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.4049\/jimmunol.121.5.2005","article-title":"Immunologic functions of Ia-bearing epidermal Langerhans cells","volume":"121","author":"Stingl","year":"1978","journal-title":"J. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/1523-1747.ep12521061","article-title":"Langerhans cells: functional aspects revealed by in vivo grafting studies","volume":"75","author":"Streilein","year":"1980","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib6","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/BF01959006","article-title":"\u00dcber die Nerven der menschlichen Haut","volume":"44","author":"Langerhans","year":"1876","journal-title":"Virchows Arch. (Pathol. Anat.)"},{"key":"10.1016\/S0171-2985(84)80117-5_bib7","first-page":"151","article-title":"A study of the branched cells of the mammalian epidermis with special reference to the fate of their division products","volume":"237","author":"Billingham","year":"1953","journal-title":"Philos. Trans. R. Soc. Lon. (Biol.)"},{"key":"10.1016\/S0171-2985(84)80117-5_bib8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/jid.1961.80","article-title":"An electron microscopic study of basal melanocytes and high level clear cells (Langerhans cells) in vitiligo","volume":"37","author":"Birbeck","year":"1961","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib9","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/jid.1968.18","article-title":"Langerhans cells in mouse skin experimentally deprived of its neural crest component","volume":"50","author":"Breathnach","year":"1967","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib10","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1242\/jcs.15.2.291","article-title":"Fine-structural identification and organization of the epidermal proliferative unit","volume":"15","author":"Allen","year":"1974","journal-title":"J. Cell. Sci."},{"key":"10.1016\/S0171-2985(84)80117-5_bib11","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1242\/jcs.17.3.413","article-title":"The fine structure and cell kinetics of mouse epidermis after wounding","volume":"17","author":"Potten","year":"1975","journal-title":"J. Cell. Sci."},{"key":"10.1016\/S0171-2985(84)80117-5_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/jid.1969.1","article-title":"Interactions between keratinocytes and dendritic cells","volume":"52","author":"Prunieras","year":"1969","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib13","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1159\/000392434","article-title":"The Langerhans cell","volume":"4","author":"Wolff","year":"1972","journal-title":"Curr. Probl. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib14","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/00000372-197900130-00003","article-title":"Histochemical analysis of Langerhans cells","volume":"1","author":"Berman","year":"1979","journal-title":"Am. J. Dermatopathol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib15","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/268245a0","article-title":"Epidermal Langerhans cells bear Fc and C3 receptors","volume":"268","author":"Stingl","year":"1977","journal-title":"Nature"},{"key":"10.1016\/S0171-2985(84)80117-5_bib16","first-page":"64","article-title":"Tissue distribution of Ia antigens and their expression on lymphocyte subpopulations","volume":"30","author":"Hammerling","year":"1976","journal-title":"Transplant. Rev."},{"key":"10.1016\/S0171-2985(84)80117-5_bib17","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/BF01844036","article-title":"Expression of Ia antigens by murine keratinizing epithelial Langerhans cells","volume":"7","author":"Rowden","year":"1978","journal-title":"Immunogenetics"},{"key":"10.1016\/S0171-2985(84)80117-5_bib18","first-page":"248","article-title":"Epidermal Langerhans cells express Ia antigen","volume":"26","author":"Klareskog","year":"1977","journal-title":"Nature"},{"key":"10.1016\/S0171-2985(84)80117-5_bib19","doi-asserted-by":"crossref","first-page":"784","DOI":"10.4049\/jimmunol.123.2.784","article-title":"Ia antigens in mouse skin are predominantly expressed on Langerhans cells","volume":"123","author":"Tamaki","year":"1979","journal-title":"J. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib20","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1600-065X.1982.tb00434.x","article-title":"Antigen presentation by vascular endothelial cells and epidermal Langerhans cells: the role of HLA-DR","volume":"66","author":"Hirschberg","year":"1982","journal-title":"Immunol. Rev."},{"key":"10.1016\/S0171-2985(84)80117-5_bib21","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/1523-1747.ep12506352","article-title":"Immunoelectron microscopic identification of Langerhans cells using a new antigenic marker","volume":"78","author":"Chu","year":"1982","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib22","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/1523-1747.ep12519909","article-title":"Surface densities of Langerhans cells in relation to rodent epidermal sites with special immunologic properties","volume":"74","author":"Bergstresser","year":"1979","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib23","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/jid.1967.82","article-title":"Quantitative studies on the Langerhans cell population of guinea pig epidermis","volume":"48","author":"Wolff","year":"1967","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib24","series-title":"Local effects of ultraviolet radiation on immune function in mice. In \u00abThe Effect of Ultraviolet Radiation on the Immune System\u00bb","first-page":"73","author":"Bergstresser","year":"1983"},{"key":"10.1016\/S0171-2985(84)80117-5_bib25","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1365-2133.1975.tb03120.x","article-title":"Cytochemical identification of AtPase-positive Langerhans cells in EDTA-separated sheets of mouse epidermis","volume":"92","author":"MacKenzie","year":"1979","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/1523-1747.ep12506298","article-title":"A developmental study of the distribution and frequency of Langerhans cells in relation to formation of patterning in mouse tail epidermis","volume":"60","author":"Schweizer","year":"1977","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib27","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF00427258","article-title":"Interepithelial cells of the oral mucosa in mice","volume":"384","author":"Burkhardt","year":"1979","journal-title":"Virchows Archiv A Path. and Histol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib28","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0002-9378(68)90012-4","article-title":"Electron microscope observations on Langerhans cells in the cervix","volume":"102","author":"Younes","year":"1968","journal-title":"Am. J. Obst. & Gyn."},{"key":"10.1016\/S0171-2985(84)80117-5_bib29","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0022-5320(73)80037-1","article-title":"Langerhans cells in the ruminal epithelium of the sheep","volume":"43","author":"Gemmell","year":"1973","journal-title":"J. Ultrastructure Research"},{"key":"10.1016\/S0171-2985(84)80117-5_bib30","first-page":"253","article-title":"Etude sur le pigment de l'epithelium conjunctival et corn\u00e9en","volume":"159","author":"Redslob","year":"1922","journal-title":"Ann. Ocul."},{"key":"10.1016\/S0171-2985(84)80117-5_bib31","first-page":"310","article-title":"Expression of Ia antigen-like molecules on cells in the corneal epithelium","volume":"18","author":"Forsum","year":"1979","journal-title":"Invest. Ophthalmol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib32","first-page":"811","article-title":"Electron microscopic study of the development of the mouse corneal epithelium","volume":"10","author":"Pei","year":"1971","journal-title":"Invest. Ophthal."},{"key":"10.1016\/S0171-2985(84)80117-5_bib33","first-page":"227","article-title":"Pulmonary Langerhans' cells in patients with fibrotic lung disorders","volume":"44","author":"Kawanami","year":"1981","journal-title":"Lab. Invest."},{"key":"10.1016\/S0171-2985(84)80117-5_bib34","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/1523-1747.ep12291861","article-title":"Langerhans cells in epidermoid metaplasia","volume":"56","author":"Wong","year":"1971","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib35","first-page":"271","article-title":"Cells containing Birbeck granules in human thymus","volume":"19","author":"Hoshino","year":"1970","journal-title":"J. Electron. Microsc."},{"key":"10.1016\/S0171-2985(84)80117-5_bib36","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/BF00347028","article-title":"Macrophages containing Langerhans cell granules in normal lymph nodes of the rabbit","volume":"98","author":"Kondo","year":"1969","journal-title":"Zeitschrift f\u00fcr Zellforschung and Mikroskopische Anatomie"},{"key":"10.1016\/S0171-2985(84)80117-5_bib37","first-page":"371","article-title":"Identification par la microscopie eletronique de particules de nature probablement virale dans les lesions granulomateuses d'une histiocytose \u00abX\u00bb polmonaire","volume":"261","author":"Basset","year":"1965","journal-title":"C.R. Acad. Sci. (Paris)"},{"key":"10.1016\/S0171-2985(84)80117-5_bib38","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/1097-0142(197108)28:2<467::AID-CNCR2820280228>3.0.CO;2-9","article-title":"Malignant histiocytosis: A case of generalized histiocytosis with infiltration of Langerhans granules containing histiocytes","volume":"28","author":"Imamura","year":"1971","journal-title":"Cancer"},{"key":"10.1016\/S0171-2985(84)80117-5_bib39","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/1523-1747.ep12525745","article-title":"Ultraviolet light depletes surface markers of Langerhans cells","volume":"76","author":"Aberber","year":"1981","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib40","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/0008-8749(81)90247-1","article-title":"The effects of ultraviolet light and certain drugs on Ia-bearing Langerhans cells in murine epidermis","volume":"60","author":"Norlund","year":"1981","journal-title":"Cell Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib41","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/1523-1747.ep12493242","article-title":"The effects of 8-methoxypsoralen and longwave ultraviolet light on Langerhans cells","volume":"77","author":"Okamoto","year":"1981","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib42","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/jid.1963.35","article-title":"The effect of ultraviolet radiation on experimental cutaneous sensitization in guinea pigs","volume":"40","author":"Haniszko","year":"1963","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib43","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1084\/jem.155.1.291","article-title":"Effect of glucocorticosteroids on epidermal Langerhans cells","volume":"155","author":"Belsito","year":"1982","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0171-2985(84)80117-5_bib44","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/1523-1747.ep12533397","article-title":"Modulation of expression of epidermal Langerhans cell properties following in situ exposure to glucocorticoids","volume":"80","author":"Berman","year":"1983","journal-title":"J. Invest. Derm."},{"key":"10.1016\/S0171-2985(84)80117-5_bib45","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/jid.1968.20","article-title":"The disappearance and regeneration of Langerhans cells following epidermal injury","volume":"50","author":"Lessard","year":"1968","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib46","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1084\/jem.155.3.863","article-title":"Depletion of epidermal Langerhans cells and Ia immunogenicity from tape-stripped mouse skin","volume":"155","author":"Streilein","year":"1982","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0171-2985(84)80117-5_bib47","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1126\/science.157.3787.439","article-title":"Langerhans cells: uptake of tritiated thymidine","volume":"157","author":"Giacometti","year":"1967","journal-title":"Science (Wash. D.C.)"},{"key":"10.1016\/S0171-2985(84)80117-5_bib48","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/aja.1001440202","article-title":"Labelling of murine epidermal Langerhans cells with 3H-thymidine","volume":"144","author":"MacKenzie","year":"1975","journal-title":"Am. J. Anat."},{"key":"10.1016\/S0171-2985(84)80117-5_bib49","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1038\/282324a0","article-title":"Epidermal Langerhans cells are derived from cells originating in bone marrow","volume":"282","author":"Katz","year":"1979","journal-title":"Nature (Lond.)"},{"key":"10.1016\/S0171-2985(84)80117-5_bib50","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/282321a0","article-title":"Mouse epidermal Ia molecules have a bone marrow origin","volume":"282","author":"Frelinger","year":"1979","journal-title":"Nature"},{"key":"10.1016\/S0171-2985(84)80117-5_bib51","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1073\/pnas.80.6.1650","article-title":"Biology of Langerhans cells selective migration of Langerhans cells into allogeneic and xenogeneic grafts in nude mice","volume":"80","author":"Kreuger","year":"1983","journal-title":"Proc. Natl. Acad. Sci. (USA)"},{"key":"10.1016\/S0171-2985(84)80117-5_bib52","first-page":"95","article-title":"The Langerhans Cell","volume":"3","author":"Rowden","year":"1981","journal-title":"Critical Reviews in Immunology"},{"key":"10.1016\/S0171-2985(84)80117-5_bib53","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1084\/jem.127.2.277","article-title":"Antigens in immunity. IV. Ultrastructural features of antigen capture in primary and secondary lymphoid follicles","volume":"127","author":"Nossal","year":"1968","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0171-2985(84)80117-5_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2776(08)60919-0","article-title":"The regulatory role of macrophages in antigenic stimulation. II. Symbiotic relationship between lymphocytes and macrophages","volume":"31","author":"Unanue","year":"1981","journal-title":"Adv. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4049\/jimmunol.132.1.1","article-title":"Antigen presentation: comments on its regulation and mechanism","volume":"132","author":"Unanue","year":"1984","journal-title":"J. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib56","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1600-065X.1980.tb01042.x","article-title":"Dendritic cells, features and functions","volume":"53","author":"Steinman","year":"1980","journal-title":"Immunol. Rev."},{"key":"10.1016\/S0171-2985(84)80117-5_bib57","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1084\/jem.158.1.174","article-title":"The relative efficacy of human monocytes and dendritic cells as accessory cells for T cell regulation","volume":"158","author":"van Voorhis","year":"1983","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0171-2985(84)80117-5_bib58","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/1523-1747.ep12521083","article-title":"Langerhans cells as macrophages in skin and lymphoid organs","volume":"75","author":"Thorbeck","year":"1980","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib59","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1399-0039.1975.tb00633.x","article-title":"Lymphocyte activating alloantigens of human epidermal cells","volume":"6","author":"Hirschberg","year":"1975","journal-title":"Tissue Antigens"},{"key":"10.1016\/S0171-2985(84)80117-5_bib60","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/00007890-197903000-00011","article-title":"Stimulation of allogeneic lymphocytes by skin epidermal cells in the rat","volume":"27","author":"Tanaka","year":"1979","journal-title":"Transplantation"},{"key":"10.1016\/S0171-2985(84)80117-5_bib61","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/1523-1747.ep12544055","article-title":"Analogous functions of macrophages and Langerhans cells in the initiation of the immune response","volume":"71","author":"Stingl","year":"1978","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib62","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/1523-1747.ep12517984","article-title":"Epidermal cell-induced generation of cytotoxic T-lymphocyte responses against alloantigens or Tnp-modified syngeneic cells: Requirement for Ia-positive Langerhans cells","volume":"81","author":"Pehamberger","year":"1983","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib63","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1159\/000230559","article-title":"Inability of UV-irradiated lymphocytes to stimulate allogeneic cells in mixed lymphocyte culture","volume":"41","author":"Lindahl-Kiessling","year":"1971","journal-title":"Int. Arch. Allergy Appl. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib64","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/00007890-198104000-00006","article-title":"Impairment of antigen-presenting cell function by ultraviolet radiation. II. Effet of in vitro ultraviolet irradiation on antigenpresenting cells","volume":"31","author":"Fox","year":"1981","journal-title":"Transplantation"},{"key":"10.1016\/S0171-2985(84)80117-5_bib65","series-title":"The Effects of Ultraviolet Radiation on the Immune System","first-page":"61","article-title":"The effects of ultraviolet radiation on Langerhans cells","author":"Stingl","year":"1983"},{"key":"10.1016\/S0171-2985(84)80117-5_bib66","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/282326a0","article-title":"Corneal allografts fail to express Ia antigens","volume":"282","author":"Streilein","year":"1979","journal-title":"Nature (Lond.)"},{"key":"10.1016\/S0171-2985(84)80117-5_bib67","first-page":"513","article-title":"On the Ia immunogenicity of mouse corneal allografts infiltrated with Langerhans cells","volume":"25","author":"Rubsamen","year":"1984","journal-title":"Invest. Ophthal."},{"key":"10.1016\/S0171-2985(84)80117-5_bib68","doi-asserted-by":"crossref","first-page":"445","DOI":"10.4049\/jimmunol.124.1.445","article-title":"Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB","volume":"124","author":"Toews","year":"1980","journal-title":"J. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib69","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/1523-1747.ep12482453","article-title":"Langerhans cell function dictates induction of contact hypersensitivity or unresponsiveness to DNFB in Syrian hamsters","volume":"77","author":"Streilein","year":"1981","journal-title":"J. Invest. Derm."},{"key":"10.1016\/S0171-2985(84)80117-5_bib70","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.4049\/jimmunol.126.5.1892","article-title":"Relationship between epidermal Langerhans cell density, ATPase activity, and the induction of contact hypersensitivity","volume":"126","author":"Lynch","year":"1981","journal-title":"J. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib71","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2133.1981.tb00039.x","article-title":"The influence of ultraviolet radiation on allergic contact dermatitis in the guinea pig. I. UVB radiation","volume":"104","author":"Morison","year":"1981","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib72","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00007890-198402000-00015","article-title":"Induction of H-2 restricted contact hypersensitivity by hapten-derivatized skin grafts","volume":"37","author":"Streilein","year":"1984","journal-title":"Transplantation"},{"key":"10.1016\/S0171-2985(84)80117-5_bib73","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1084\/jem.151.2.362","article-title":"Role of antigen-presenting cells in the development and persistence of contact hypersensitivity","volume":"151","author":"Ptak","year":"1980","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0171-2985(84)80117-5_bib74","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/1523-1747.ep12526115","article-title":"The role of epidermal cells in the induction and suppression of contact sensitivity","volume":"76","author":"Tamaki","year":"1981","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib75","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1084\/jem.155.5.1344","article-title":"Specialized antigen-presenting cells","volume":"155","author":"Britz","year":"1982","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0171-2985(84)80117-5_bib76","doi-asserted-by":"crossref","first-page":"261","DOI":"10.4049\/jimmunol.127.1.261","article-title":"Induction of tolerance to topically applied TNCB using TNP-conjugated ultraviolet light-irradiated epidermal cells","volume":"127","author":"Sauder","year":"1981","journal-title":"J. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib77","first-page":"440","article-title":"Haptenderivatized, purified epidermal Langerhans cells induce contact hypersensitivity without down regulation","volume":"82","author":"Sullivan","year":"1984","journal-title":"J. Invest. Derm."},{"key":"10.1016\/S0171-2985(84)80117-5_bib78","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4049\/jimmunol.132.2.563","article-title":"Epidermal antigen-presenting cells in activation of suppression: identification of a new functional type of ultraviolet radiation-resistant epidermal cell","volume":"132","author":"Granstein","year":"1984","journal-title":"J. Immunol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib79","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/1523-1747.ep12518332","article-title":"Thy-1 antigen-bearing dendritic cells populate murine epidermis","volume":"81","author":"Bergstresser","year":"1983","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib80","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/1523-1747.ep12518326","article-title":"Expression of Thy-1 antigen by murine epidermal cells","volume":"81","author":"Tschachler","year":"1983","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib81","doi-asserted-by":"crossref","unstructured":"P.R. Bergstresser, R.E. Tigelaar, J.W. Streilein, 1984. Thy-1 antigen-bearing dendritic cells in murine epidermis are derived from bone marrow precursors. J. Invest. Dermatol. (in press).","DOI":"10.1111\/1523-1747.ep12262587"},{"key":"10.1016\/S0171-2985(84)80117-5_bib82","first-page":"153","article-title":"Effects of ultraviolet irradiation on the acquisition and expression of tick resistance in guinea pigs","volume":"51","author":"Nithiuthai","year":"1984","journal-title":"Immunology"},{"key":"10.1016\/S0171-2985(84)80117-5_bib83","first-page":"133","article-title":"Significant changes in epidermal Langerhans cells of guinea pigs infected with ticks","volume":"51","author":"Nithiuthai","year":"1984","journal-title":"Immunology"},{"key":"10.1016\/S0171-2985(84)80117-5_bib84","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/1523-1747.ep12547071","article-title":"Lymphocyte traffic, T-cell malignancies and the skin","volume":"71","author":"Streilein","year":"1978","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib85","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/1523-1747.ep12536743","article-title":"Skin associated lymphoid tissues (SALT)","volume":"80","author":"Streilein","year":"1983","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S0171-2985(84)80117-5_bib86","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1093\/jnci\/53.5.1333","article-title":"Antigenicity of murine skin tumors induced by ultraviolet light","volume":"53","author":"Kripke","year":"1974","journal-title":"J. Natl. Cancer Inst."}],"container-title":["Immunobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298584801175?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0171298584801175?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T16:56:57Z","timestamp":1759251417000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0171298584801175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,12]]},"references-count":86,"journal-issue":{"issue":"3-5","published-print":{"date-parts":[[1984,12]]}},"alternative-id":["S0171298584801175"],"URL":"https:\/\/doi.org\/10.1016\/s0171-2985(84)80117-5","relation":{},"ISSN":["0171-2985"],"issn-type":[{"value":"0171-2985","type":"print"}],"subject":[],"published":{"date-parts":[[1984,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Langerhans Cells: Antigen Presenting Cells of the Epidermis","name":"articletitle","label":"Article Title"},{"value":"Immunobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/S0171-2985(84)80117-5","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1984 Gustav Fischer Verlag \u00b7 Stuttgart \u00b7 New York. Published by Elsevier GmbH All rights reserved.","name":"copyright","label":"Copyright"}]}}