{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T19:16:01Z","timestamp":1774379761967,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2000,8,1]],"date-time":"2000-08-01T00:00:00Z","timestamp":965088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular and Cellular Endocrinology"],"published-print":{"date-parts":[[2000,8]]},"DOI":"10.1016\/s0303-7207(00)00291-4","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T14:21:08Z","timestamp":1027606868000},"page":"9-14","source":"Crossref","is-referenced-by-count":33,"title":["Clinical application of GnRH-antagonists"],"prefix":"10.1016","volume":"166","author":[{"given":"R.E","family":"Felberbaum","sequence":"first","affiliation":[]},{"given":"M","family":"Ludwig","sequence":"additional","affiliation":[]},{"given":"K","family":"Diedrich","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"issue":"Suppl. 2","key":"10.1016\/S0303-7207(00)00291-4_BIB1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1093\/humrep\/9.suppl_2.36","article-title":"Endocrinology of the ovary","volume":"9","author":"Adashi","year":"1994","journal-title":"Hum. Reprod."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB2","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/oxfordjournals.humrep.a019058","article-title":"Hormonal profile during the follicular phase in cycles stimulated with a combination of human menopausal gonadotrophin and gonadotrophin-releasing hormone antagonist (Cetrorelix)","volume":"11","author":"Albano","year":"1996","journal-title":"Hum. Reprod."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB3","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/S0015-0282(97)81407-0","article-title":"Comparison of different doses of gonadotropin-releasing hormone antagonist Cetrorelix during controlled ovarian hyperstimulation","volume":"67","author":"Albano","year":"1997","journal-title":"Fertil. Steril."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB4","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000125862","article-title":"Recovery of pituitary\u2013gonadal function in male and female rats after prolonged administration of a potent antagonist of luteinizing hormone-releasing hormone (SB-75)","volume":"54","author":"Bokser","year":"1991","journal-title":"Neuroendocrinology"},{"key":"10.1016\/S0303-7207(00)00291-4_BIB5","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0015-0282(99)00448-3","article-title":"GnRH antagonists","volume":"73","author":"Devroey","year":"2000","journal-title":"Fertil. Steril."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB6","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1016\/0002-9378(91)90037-R","article-title":"The gonadotrophin-releasing hormone antagonist (Nal\u2013Glu) acutely blocks the luteinizing hormone surge but allows for resumption of folliculogenesis in normal women","volume":"165","author":"Dittkoff","year":"1991","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB7","unstructured":"Emons, G., Ortmann, O., Pahwa, G.S., Oberheuser, F., Schulz, K.D., 1993. Treatment of ovarian cancer with GnRH-analogues. In: Emons, G., Ghraf, R., Schulz, K.D. (Eds.), GnRH and its analogues in gynecological oncology. Hansischer Medizinischer Verlag, Hamburg, pp. 57\u201372."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB8","first-page":"32","article-title":"First results of the GnRH-antagonist Cetrorelix in patients with ovarian cancer","volume":"13","author":"Emons","year":"1999","journal-title":"Gyn. Endocrinol. (Suppl. 1)"},{"key":"10.1016\/S0303-7207(00)00291-4_BIB9","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0301-2115(95)02138-W","article-title":"Preserved pituitary response under ovarian stimulation with HMG and GnRH-antagonists (Cetrorelix) in women with tubal infertility","volume":"61","author":"Felberbaum","year":"1995","journal-title":"Eur. J. Obstet. Gyn. Reprod. Biol."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB10","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/BF02065939","article-title":"Hormone profiles under ovarian stimulation with human menopausal gonadotrophin (HMG) and concomitant administration of the gonadotropin releasing hormone (GnRH)-antagonist Cetrorelix at different dosages","volume":"13","author":"Felberbaum","year":"1996","journal-title":"J. Ass. Reprod. Gen."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB11","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1093\/humrep\/13.6.1660","article-title":"Treatment of uterine fibroids with a slow release formulation of the gonadotrophin releasing hormone antagonist Cetrorelix","volume":"13","author":"Felberbaum","year":"1998","journal-title":"Hum. Reprod."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB12","unstructured":"Felberbaum, R., K\u00fcpker, W., 2000. Unpublished data."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB13","doi-asserted-by":"crossref","unstructured":"The Ganirelix dose-finding study group, 1998. A double-blind, randomized, dose-finding study to assess the efficacy of the gonadotrophin-releasing hormone antagonist ganirelix (Org 37462) to prevent premature luteinizing hormone surges in women undergoing ovarian stimulation with recombinant follicle stimulating hormone (Puregon\u00ae). Hum. Reprod. 13, 3023\u20133031.","DOI":"10.1093\/humrep\/13.11.3023"},{"key":"10.1016\/S0303-7207(00)00291-4_BIB14","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1093\/humrep\/12.9.2028","article-title":"Treatment of uterine leiomyomas with luteinizing hormone-releasing hormone antagonist Cetrorelix","volume":"12","author":"Gonzalez-Barcena","year":"1997","journal-title":"Hum. Reprod."},{"issue":"Suppl. 3","key":"10.1016\/S0303-7207(00)00291-4_BIB15","first-page":"24","article-title":"Cetrorelix multidose protocol: results of the largest multinational study with an antagonist in ART","volume":"4","author":"Hamm","year":"1999","journal-title":"Middle East Fertil. Soc. J."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB16","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1093\/jnci\/89.23.1803","article-title":"Growth inhibition of ovarian cancers by cytotoxic analogues of luteinizing hormone-releasing hormone","volume":"89","author":"Miyakazi","year":"1997","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB17","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S0015-0282(16)56933-7","article-title":"The single or dual administration of the gonadotrophin-releasing hormone antagonist Cetrorelix in an in vitro fertilization\u2013embryo transfer programme","volume":"62","author":"Olivennes","year":"1994","journal-title":"Fertil. Steril."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB18","first-page":"1382","article-title":"Scheduled administration of a gonadotrophin releasing hormone antagonist (Cetrorelix) on day 8 of in-vitro fertilization cycles: a pilot study","volume":"10","author":"Olivennes","year":"1995","journal-title":"Hum. Reprod."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB19","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0015-0282(16)58404-0","article-title":"Triggering of ovulation by a gonadotropin-releasing hormone (GnRH) agonist in patients pretreated with a GnRH antagonist","volume":"66","author":"Olivennes","year":"1996","journal-title":"Fertil. Steril."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB20","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/j.1939-4640.1993.tb00373.x","article-title":"Recovery of pituitary\u2013gonadal function in male rats after long-term suppression induced by a single injection of microcapsules of LH\u2013RH antagonist Cetrorelix (SK-75)","volume":"14","author":"Pinski","year":"1993","journal-title":"J. Androl."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB21","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1093\/oxfordjournals.humrep.a136219","article-title":"Development and applications of luteinizing hormone-releasing hormone antagonists in the treatment of infertility: an overview","volume":"10","author":"Reissmann","year":"1995","journal-title":"Hum. Reprod."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB22","unstructured":"Schally, A.V., Nagy, A., Szepashazi, K. et al., 1996. LH\u2013RH analogues with cytotoxic radicals. In: Filicori, M., Flamigni, C. (Eds.), Treatment with GnRH analogues: controversies and perspectives. Parthenon Publishing Group, Carnforth, UK, pp. 33\u201344"},{"key":"10.1016\/S0303-7207(00)00291-4_BIB23","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1093\/oxfordjournals.humrep.a138685","article-title":"Recombinant human follicle-stimulating hormone and ovarian response in gonadotrophin-deficient women","volume":"9","author":"Schoot","year":"1994","journal-title":"Hum. Reprod."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB24","unstructured":"Tunn, U.W., Goldschmidt, A.J.W., Schweikert, H.U., 1994. Tumor flare and treatment of prostate cancer with LH\u2013RH-agonists: Prevention by simultaneous antiandrogenic treatment? In: Klingm\u00fcller, D., Wildt, L. (Eds.), GnRH-analogues in therapy. Georg Thieme Verlag, Stuttgart, pp. 66\u201382."},{"key":"10.1016\/S0303-7207(00)00291-4_BIB25","unstructured":"Westphalen, S., Emons, G., 1999. GnRH analogues in ovarian, breast and endometrial cancers. In: Lunenfeld, B. (Ed.), GnRh analogues\u2014the state of the art at the millennium. Parthenon Publishing Group, New York, pp. 105\u2013120"}],"container-title":["Molecular and Cellular Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720700002914?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0303720700002914?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,12,31]],"date-time":"2023-12-31T11:47:26Z","timestamp":1704023246000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0303720700002914"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,8]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,8]]}},"alternative-id":["S0303720700002914"],"URL":"https:\/\/doi.org\/10.1016\/s0303-7207(00)00291-4","relation":{},"ISSN":["0303-7207"],"issn-type":[{"value":"0303-7207","type":"print"}],"subject":[],"published":{"date-parts":[[2000,8]]}}}