{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T01:02:04Z","timestamp":1771030924162,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Letters"],"published-print":{"date-parts":[[2003,1]]},"DOI":"10.1016\/s0304-3835(02)00513-x","type":"journal-article","created":{"date-parts":[[2002,12,27]],"date-time":"2002-12-27T15:52:40Z","timestamp":1041004360000},"page":"237-247","source":"Crossref","is-referenced-by-count":98,"title":["L1 adhesion molecule (CD 171) in development and progression of human malignant melanoma"],"prefix":"10.1016","volume":"189","author":[{"given":"Mina","family":"Fogel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Mechtersheimer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Huszar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asya","family":"Smirnov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel","family":"Abu-Dahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Tilgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Reichrath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Georg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Altevogt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Gutwein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0304-3835(02)00513-X_BIB1","series-title":"Cutaneous Melanoma","first-page":"82","author":"Balch","year":"1998"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1023\/A:1006304806799","article-title":"Cell adhesion molecules in the development and progression of malignant melanoma","volume":"18","author":"Johnson","year":"1999","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB3","first-page":"3835","article-title":"Melanoma cell-cell interactions are mediated through heterophilic Mel-CAM\/ligand adhesion","volume":"57","author":"Shih","year":"1997","journal-title":"Cancer Res."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB4","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/S0002-9440(10)65719-7","article-title":"Role of the beta3 integrin subunit in human primary melanoma progression: multifunctional activities associated with alpha(v)beta3 integrin expression","volume":"153","author":"Seftor","year":"1998","journal-title":"Am. J. Pathol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB5","first-page":"6757","article-title":"Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression","volume":"50","author":"Albelda","year":"1990","journal-title":"Cancer Res."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB6","unstructured":"List of CD molecules, http:\/\/www.ncbi.nlm.nih.gov\/PROW\/guide\/1813332452"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB7","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0896-6273(00)80192-0","article-title":"The L1 family of neural cell adhesion molecules: old proteins performing new tricks","volume":"17","author":"Hortsch","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB8","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/S0955-0674(97)80115-9","article-title":"Neural recognition molecules and synaptic plasticity","volume":"9","author":"Schachner","year":"1997","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB9","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0959-4388(98)80012-3","article-title":"Neural cell recognition molecule L1: from cell biology to human hereditary brain malformations","volume":"8","author":"Br\u00fcmmendorf","year":"1998","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB10","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.1093\/emboj\/18.17.4744","article-title":"Pathological missense mutations of neural cell adhesion molecule L1 affect homophilic and heterophilic binding activities","volume":"18","author":"deAngelis","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB11","doi-asserted-by":"crossref","first-page":"24602","DOI":"10.1074\/jbc.274.35.24602","article-title":"Integrin and neurocan binding to L1 involves distinct Ig domains","volume":"274","author":"Oleszewski","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB12","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1083\/jcb.200101099","article-title":"Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins","volume":"155","author":"Mechtersheimer","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB13","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/ijc.2910430428","article-title":"Differential expression of cell adhesion molecules in variants of K1735 melanoma cells differing in metastatic capacity","volume":"43","author":"Linnemann","year":"1989","journal-title":"Int. J. Cancer"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB14","doi-asserted-by":"crossref","first-page":"15490","DOI":"10.1074\/jbc.275.20.15490","article-title":"Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells","volume":"275","author":"Gutwein","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB15","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1023\/A:1004062127338","article-title":"Immunohistochemical analysis of DNA mismatch repair enzyme hMSH-2 in normal human skin and basal cell carcinomas","volume":"32","author":"Rass","year":"2000","journal-title":"Histochem. J."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB16","first-page":"299","article-title":"Vitamin D receptor (VDR) expression is not a prognostic factor in cervical cancer","volume":"22","author":"Friedrich","year":"2002","journal-title":"Anticancer Res."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB17","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/00000372-200108000-00002","article-title":"The p75 neurotrophin receptor, relative to other Schwann cell and melanoma markers, is abundantly expressed in spindled melanomas","volume":"23","author":"Iwamoto","year":"2001","journal-title":"Am. J. Dermatopathol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB18","first-page":"251","article-title":"The sun and malignant melanoma","volume":"43","author":"Garbe","year":"1992","journal-title":"Hautarzt"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB19","series-title":"Cutaneous Melanoma","first-page":"13","article-title":"Epidemiologic Studies","author":"Armstrong","year":"1998"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB20","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0092-8674(94)90149-X","article-title":"Expression of the integrin alpha 4 beta 1 on melanoma cells can inhibit the invasive stage of metastasis formation","volume":"77","author":"Qian","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB21","doi-asserted-by":"crossref","first-page":"4821","DOI":"10.1073\/pnas.93.10.4821","article-title":"Predominant role of alpha 4-integrins for distinct steps of lymphoma metastasis","volume":"93","author":"Gosslar","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB22","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1126\/science.285.5430.1028","article-title":"Integrin signaling","volume":"285","author":"Giancotti","year":"1999","journal-title":"Science"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB23","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S0968-0004(00)01605-4","article-title":"Signaling networks linking integrins and rho family GTPases","volume":"25","author":"Schwartz","year":"2000","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB24","doi-asserted-by":"crossref","first-page":"2530","DOI":"10.1200\/JCO.2002.05.033","article-title":"CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease","volume":"20","author":"Thies","year":"2002","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB25","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0002-9440(10)61725-7","article-title":"Cis interaction of the cell adhesion molecule CEACAM1 with integrin beta(3)","volume":"159","author":"Brummer","year":"2001","journal-title":"Am. J. Pathol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB26","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.1002\/eji.1830231130","article-title":"L1 adhesion molecule on mouse leukocytes: regulation and involvement in endothelial cell binding","volume":"23","author":"Hubbe","year":"1993","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB27","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1083\/jcb.131.6.1881","article-title":"The L1 adhesion molecule is a cellular ligand for VLA-5","volume":"131","author":"Ruppert","year":"1995","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB28","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1091\/mbc.12.9.2699","article-title":"Involvement of integrin alpha(v)beta(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells","volume":"12","author":"Voura","year":"2001","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/S0304-3835(02)00513-X_BIB29","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1242\/jcs.112.16.2667","article-title":"Metalloproteinase-mediated release of the ectodomain of L1 adhesion molecule","volume":"112","author":"Beer","year":"1999","journal-title":"J. Cell Sci."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB30","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1083\/jcb.132.3.475","article-title":"Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3","volume":"132","author":"Montgomery","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB31","doi-asserted-by":"crossref","DOI":"10.1096\/fj.02-0430fje","article-title":"ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles","author":"Gutwein","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/S0304-3835(02)00513-X_BIB32","author":"Fogel","year":"2002","journal-title":"L1 adhesion molecule and the progression of ovarian and uterine carcinomas"}],"container-title":["Cancer Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030438350200513X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030438350200513X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T05:39:39Z","timestamp":1622525979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030438350200513X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["S030438350200513X"],"URL":"https:\/\/doi.org\/10.1016\/s0304-3835(02)00513-x","relation":{},"ISSN":["0304-3835"],"issn-type":[{"value":"0304-3835","type":"print"}],"subject":[],"published":{"date-parts":[[2003,1]]}}}