{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T15:39:48Z","timestamp":1770997188893,"version":"3.50.1"},"reference-count":96,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1998,4,1]],"date-time":"1998-04-01T00:00:00Z","timestamp":891388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["General Pharmacology: The Vascular System"],"published-print":{"date-parts":[[1998,4]]},"DOI":"10.1016\/s0306-3623(97)00070-0","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T15:20:46Z","timestamp":1027610446000},"page":"465-475","source":"Crossref","is-referenced-by-count":15,"title":["Antidepressant Drugs in the Elderly"],"prefix":"10.1016","volume":"30","author":[{"given":"Pietro","family":"Gareri","sequence":"first","affiliation":[]},{"given":"Giuseppe","family":"Stilo","sequence":"additional","affiliation":[]},{"given":"Ida","family":"Bevacqua","sequence":"additional","affiliation":[]},{"given":"Rosario","family":"Mattace","sequence":"additional","affiliation":[]},{"given":"Guido","family":"Ferreri","sequence":"additional","affiliation":[]},{"given":"Giovambattista","family":"De Sarro","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0306-3623(97)00070-0_BIB1","first-page":"183","article-title":"Imipramine and desipramine disposition in the elderly","volume":"232","author":"Abernethy","year":"1985","journal-title":"J.Pharmac. Exp. Ther."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB91","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1192\/bjp.143.5.527","article-title":"The prognosis of depression in old age","volume":"143","author":"Abou-Saleh","year":"1983","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB2","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1136\/bmj.4.5686.764","article-title":"Steady state plasma levels of nortriptyline in twins","volume":"2","author":"Alexanderson","year":"1969","journal-title":"Br. Med. J."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB3","first-page":"51","article-title":"Sedativo-ipnotici ed ansiolitici anche nell'anziano","volume":"4","author":"Allen","year":"1987","journal-title":"Geriatrics"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB4","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1192\/S0007125000297511","article-title":"The pharmacology of reversible monoamine oxidase inhibitors","volume":"155","author":"Amrein","year":"1989","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB5","first-page":"311","article-title":"Sertraline","volume":"48","author":"Auster","year":"1993","journal-title":"Am. Fam. Phys."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB6","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2165\/00003495-198937010-00008","article-title":"Risk factors in geriatric drug prescribing","volume":"37","author":"Beers","year":"1989","journal-title":"Drugs"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB7","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1056\/NEJM198901193200306","article-title":"Depression in the elderly","volume":"320","author":"Blazer","year":"1989","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB8","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/0024-3205(93)90194-8","article-title":"Blockade by newly developed antidepressants of biogenic amine uptake into rat brain synaptosomes","volume":"52","author":"Bolden-Watson","year":"1993","journal-title":"Life Sci."},{"issue":"3","key":"10.1016\/S0306-3623(97)00070-0_BIB9","doi-asserted-by":"crossref","first-page":"195","DOI":"10.2165\/00002512-199303030-00002","article-title":"Drug therapy for geriatric depression","volume":"3","author":"Bressler","year":"1993","journal-title":"Drugs Aging"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB10","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1136\/hrt.35.5.527","article-title":"Effect of posture on blood pressure in the elderly","volume":"35","author":"Caird","year":"1973","journal-title":"Br. Heart J."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB11","first-page":"559","article-title":"Depression in the elderly","volume":"87","author":"Casey","year":"1994","journal-title":"South. Med. J."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB12","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1055\/s-2007-1014372","article-title":"The pharmacologic treatment of depression","volume":"26","author":"Cassano","year":"1993","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB92","series-title":"Suicide","first-page":"253","article-title":"The aged","author":"Charatan","year":"1979"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB13","doi-asserted-by":"crossref","first-page":"342","DOI":"10.2165\/00003495-198529040-00003","article-title":"Genetically determined variability in acetylation and oxidation","volume":"29","author":"Clark","year":"1985","journal-title":"Drugs"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB14","doi-asserted-by":"crossref","unstructured":"Clerc G. E., Ruimy P. and Verdeau-Pailles J. on behalf of the Venlafaxine French Inpatient Study Group. (1994) A double-blind comparison of venlafaxine and fluoxetine in patients hospitalized for major depression and melancholia. Intern. Clin. Psychopharm. 9, 139\u2013143.","DOI":"10.1097\/00004850-199409000-00001"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB15","first-page":"417","article-title":"Anti-depressive agents and memory","volume":"19","author":"Danion","year":"1993","journal-title":"Encephale."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB16","doi-asserted-by":"crossref","first-page":"394","DOI":"10.2165\/00003088-198005040-00007","article-title":"Pharmacokinetics of single oral doses of nortriptyline in depressed elderly hospital patients and young elderly volunteers","volume":"5","author":"Dawling","year":"1980","journal-title":"Clin. Pharmacokin."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB17","first-page":"394","article-title":"Lithium treatment and the geriatric population","volume":"28","author":"DeAngelis","year":"1990","journal-title":"Int. J. Clin. Pharmac. Ther. and Toxic."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB18","unstructured":"De Leo D. and Pavan L. (1993) Terapia farmacologic dei disturbi dell'umore. In Trattato di Gerontologia e Geriatria (Edited by Crepaldi G.), pp. 990\u20131008. UTET."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB19","first-page":"497","article-title":"Mianserin","volume":"111","author":"Demling","year":"1993","journal-title":"Fortschr. Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB20","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1093\/clinchem\/34.5.863","article-title":"Pharmacokinetic factors affecting antidepressant drug clearance and clinical effect evaluation of doxepin and imipramine\u2013new data and review","volume":"34","author":"Ereshefsky","year":"1988","journal-title":"Clin. Chem."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB21","first-page":"115","article-title":"Recognition and management of depression in the elderly","volume":"57","author":"Finlayson","year":"1982","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB22","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/00004714-199410000-00012","article-title":"A prospective study of lithium augmentation in antidepressant-resistant geriatric depression","volume":"14","author":"Flint","year":"1994","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB93","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1754-4505.1993.tb01477.x","article-title":"Dental management of the geriatric patient with major depression","volume":"13","author":"Freidlander","year":"1993","journal-title":"Spec. Care Dentist"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB23","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1532-5415.1989.tb05873.x","article-title":"Correlation of estimated renal function parameters versus 24-hour creatinine clearance in ambulatory elderly","volume":"37","author":"Friedman","year":"1989","journal-title":"JAGS"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB24","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/1043-6618(90)90739-Z","article-title":"The pharmacokinetics of tricyclic antidepressant drugs in the elderly","volume":"22","author":"Furlanut","year":"1990","journal-title":"Pharmacol. Res."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB25","first-page":"93","article-title":"Phenelzine in social phobia","volume":"6","author":"Fyer","year":"1986","journal-title":"J. Clin. Psychophar."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB26","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/BF00199882","article-title":"The pharmacokinetics and pharmacodynamics of medifoxamine after oral administration in healthy elderly volunteers","volume":"46","author":"Gainsborough","year":"1994","journal-title":"Eur. J. Clin. Pharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB27","first-page":"181","article-title":"La terapia farmacologica nel paziente anziano","volume":"135","author":"Galeotta","year":"1990","journal-title":"Clin. Ter."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB94","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1017\/S0033291700007844","article-title":"Biochemical hypothesis on antidepressant drugs","volume":"18","author":"Garattini","year":"1988","journal-title":"Psychol. Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB28","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/00004850-199400910-00004","article-title":"Paroxetine in the elderly depressed patients","volume":"9","author":"Geretsegger","year":"1994","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB95","first-page":"16","article-title":"Review of the cardiovascular effects of heterocyclic antidepressants","volume":"54","author":"Glassman","year":"1993","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB29","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000213616","article-title":"Risks of antidepressants in the elderly","volume":"40","author":"Glassman","year":"1994","journal-title":"Gerontology"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB30","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/331442a0","article-title":"Characterization of the common genetic defect in humans deficient in debrisoquine metabolism","volume":"(Lond.) 331","author":"Gonzalez","year":"1988","journal-title":"Nature"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB31","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1056\/NEJM198205063061804","article-title":"Drug disposition in old age","volume":"306","author":"Greenblatt","year":"1982","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB32","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1600-0447.1990.tb05345.x","article-title":"Pharmacokinetics of moclobemide after single and multiple oral dosing with 150 milligrams 3 times daily for 15 days","volume":"82","author":"Guentert","year":"1990","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2190\/UHL6-0X4W-FRNG-8PFF","article-title":"Antidepressant drug therapy in the elderly","volume":"16","author":"Halaris","year":"1987","journal-title":"Int. J. Psychiatry Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB34","doi-asserted-by":"crossref","first-page":"331","DOI":"10.2165\/00002512-199404040-00006","article-title":"Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders","volume":"4","author":"Haria","year":"1994","journal-title":"Drugs Aging"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB35","doi-asserted-by":"crossref","first-page":"64","DOI":"10.2165\/00002512-199506010-00006","article-title":"Fluoxetine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in older patients with depressive illness","volume":"6","author":"Harris","year":"1995","journal-title":"Drugs Aging"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB36","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/clpt.1988.8","article-title":"Dissociation of norepinephrine turnover from \u03b12 responses after clorgyline","volume":"43","author":"Hauger","year":"1988","journal-title":"Clin. Pharm. Ther."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB37","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1365-2125.1977.tb00694.x","article-title":"Age as a factor affecting lithium therapy","volume":"4","author":"Hewick","year":"1977","journal-title":"Br. J. Clin. Pharmac."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB38","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1055\/s-2007-1002354","article-title":"Paroxetine","volume":"62","author":"Hiemke","year":"1994","journal-title":"Fortschr. Neurol. Psychiatr."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB39","doi-asserted-by":"crossref","first-page":"278","DOI":"10.2165\/00002512-199303030-00008","article-title":"Paroxetine. A review of its pharmacology, therapeutic use in depression and therapeutic potential in diabetic neuropathy","volume":"3","author":"Holliday","year":"1993","journal-title":"Drugs Aging"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB40","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1532-5415.1982.tb01987.x","article-title":"Treating geriatric depression","volume":"30","author":"Jarvik","year":"1982","journal-title":"JAGS"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB41","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/00006842-197503000-00006","article-title":"A review of the cardiovascular effects and toxicity of tricyclic antidepressants","volume":"37","author":"Jefferson","year":"1975","journal-title":"Psychosom. Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB42","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1016\/0024-3205(80)90604-9","article-title":"Antagonism between long acting monoamineoxidase inhibitors (MAOI) and MD 780515, a new specific and reversible MAOI","volume":"26","author":"Kan","year":"1980","journal-title":"Life Sci."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB43","first-page":"101","article-title":"Drug treatment of depression in the frail elderly","volume":"29","author":"Katz","year":"1993","journal-title":"Psychopharmacol. Bull."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB44","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1006\/pmed.1994.1128","article-title":"Prevention of depression, recurrence and complications in late life","volume":"23","author":"Katz","year":"1994","journal-title":"Prev. Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB45","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00004850-199300820-00001","article-title":"A prospective evaluation of the hepatotoxicity of lofepramine in the elderly","volume":"8","author":"Kelly","year":"1993","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB46","doi-asserted-by":"crossref","first-page":"266","DOI":"10.2165\/00002512-199101040-00003","article-title":"Treatment considerations for the depressed geriatric medical patient","volume":"1","author":"Koenig","year":"1991","journal-title":"Drugs Aging"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB47","first-page":"57","article-title":"Tyramine pressure effect in man","volume":"26","author":"Korn","year":"1988","journal-title":"J. Neural. Transm."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB48","first-page":"118","article-title":"Geriatric drug therapy","volume":"34","author":"Lamy","year":"1986","journal-title":"Am. Fam. Phys."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB49","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3109\/10401239309148825","article-title":"Delirium during fluoxetine treatment. A case report","volume":"5","author":"Leinonen","year":"1993","journal-title":"Ann. Clin. Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB50","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/0278-5846(94)90100-7","article-title":"Serum mianserin and ageing","volume":"18","author":"Leinonen","year":"1994","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB51","first-page":"449","article-title":"A practical approach to the management of depression","volume":"34","author":"Lim","year":"1993","journal-title":"Singapore Med. J."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB52","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/00004850-199300810-00001","article-title":"A pharmacological comparison of citalopram, a bicyclic serotonin uptake inhibitor, with traditional tricyclic antidepressants","volume":"8","author":"Luo","year":"1993","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB53","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/hup.470060308","article-title":"Moclobemide pharmacokinetics in depressed patients","volume":"6","author":"Maguire","year":"1991","journal-title":"Hum. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB54","first-page":"49","article-title":"Plasma sex hormones and urinary biogenic amine metabolites during treatment of male depressed patients with the monoamine oxidase inhibitor moclobemide","volume":"13","author":"Markianos","year":"1991","journal-title":"Neuroendocrinol. Lett."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB55","first-page":"40","article-title":"Affective disorders in general practice. Treatment of 6000 patients with fluvoxamine","volume":"5","author":"Martin","year":"1987","journal-title":"Pharmatherapeutica"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB56","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1056\/NEJM198908033210507","article-title":"Management of drug therapy in the elderly","volume":"321","author":"Montamat","year":"1989","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB57","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0165-0327(90)90145-X","article-title":"The effect of moclobemide on nocturnal sleep of depressed patients","volume":"20","author":"Monti","year":"1990","journal-title":"J. Affect. Disord."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB58","doi-asserted-by":"crossref","first-page":"534","DOI":"10.2105\/AJPH.78.5.534","article-title":"Incidence of depression and anxiety","volume":"78","author":"Murphy","year":"1988","journal-title":"Am. J. Publ. Health"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB59","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1600-0447.1995.tb05921.x","article-title":"Reversible and selective inhibitors of monoamine oxidase A in the treatment of depressed elderly patients","volume":"91","author":"Nair","year":"1995","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB60","doi-asserted-by":"crossref","first-page":"10S","DOI":"10.1097\/00004714-199312002-00002","article-title":"Paroxetine","volume":"13","author":"Nemeroff","year":"1993","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB61","first-page":"3","article-title":"Evolutionary trends in the pharmacotherapeutic management of depression","volume":"55","author":"Nemeroff","year":"1994","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB62","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/BF01251917","article-title":"Selective inhibition of MAO-A but not MAO-B activity increases rat pineal melatonin","volume":"61","author":"Oxenkrug","year":"1985","journal-title":"J. Neural. Transm."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB63","first-page":"601","article-title":"Hydroxylated metabolites of tricyclic antidepressants","volume":"14","author":"Potter","year":"1979","journal-title":"Biol. Psych."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB64","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1056\/NEJM199108293250907","article-title":"The pharmacologic treatment of depression","volume":"325","author":"Potter","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB65","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1007\/BF02246238","article-title":"The effect of moclobemide and mianserine on highway driving, psychometric performance and subjective parameters, relative to placebo","volume":"106","author":"Ramaekers","year":"1992","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB66","first-page":"418","article-title":"Nortriptyline pharmacokinetics and plasma levels","volume":"46","author":"Rubin","year":"1985","journal-title":"J. Clin. Psyc."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB67","first-page":"630S","article-title":"Early clinical response in depression to venlafaxine hydrochloride","volume":"29","author":"Rudolph","year":"1991","journal-title":"Biological Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB68","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00003495-199000391-00003","article-title":"Ageing and its effects on the cardiovascular system","volume":"39","author":"Safar","year":"1990","journal-title":"Drugs"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB69","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1176\/ajp.139.1.67","article-title":"A primer on geriatric psychopharmacology","volume":"139","author":"Salzman","year":"1982","journal-title":"Am. J. Psych."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB70","first-page":"23","article-title":"Pharmacological treatment of depression in the elderly","volume":"54","author":"Salzman","year":"1993","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB71","doi-asserted-by":"crossref","first-page":"324B","DOI":"10.1097\/00002826-199202001-00627","article-title":"A randomized, double-blind, parallel group comparison of venlafaxine and clomipramine in outpatients with major depression","volume":"15","author":"Samuelian","year":"1992","journal-title":"Clin. Neuropharm."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB72","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/0024-3205(90)90529-Z","article-title":"Evidence that the reversible MAO-A inhibitor moclobemide increases prolactin secretion by a serotoninergic mechanism in healthy male volunteers","volume":"47","author":"Scheinin","year":"1990","journal-title":"Life Sci."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB73","first-page":"233","article-title":"Placebo-controlled trial of venlafaxine for the treatment of major depression","volume":"11","author":"Schweitzer","year":"1991","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB74","first-page":"104","article-title":"Comparison of venlafaxine and imipramine in the acute treatment of major depression in outpatients","volume":"55","author":"Schweitzer","year":"1994","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB75","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/00004714-199410000-00006","article-title":"Long-term safety and clinical acceptability of venlafaxine and imipramine in outpatients with major depression","volume":"14","author":"Shrivastava","year":"1994","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB76","first-page":"11","article-title":"Recognition and treatment of depression in the elderly","volume":"56","author":"Small","year":"1991","journal-title":"J. Clin. Psych."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB77","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1600-0447.1990.tb05346.x","article-title":"Absorption and disposition of moclobemide in patients with advanced age or reduced liver and kidney function","volume":"82","author":"Stoeckel","year":"1990","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB78","first-page":"247","article-title":"Efficacy and tolerance of fluvoxamine in depressive syndromes in the practice. The results of a multicentered study on 2296 patients","volume":"8","author":"Stollmaier","year":"1989","journal-title":"Nervenheilkunde"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB79","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0163-7258(81)90001-2","article-title":"Current concepts on the mechanism of action of antidepressant drugs","volume":"13","author":"Sugrue","year":"1981","journal-title":"Pharm. Ther."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB80","first-page":"1181","article-title":"Severe hyponatremia, possibly due to inappropriate antidiuretic hormone secretion, during use of the antidepressant fluoxetine","volume":"138","author":"Ten-Holt","year":"1994","journal-title":"Ned. Tijdschr. Geneeskd."},{"issue":"1","key":"10.1016\/S0306-3623(97)00070-0_BIB81","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1097\/00004714-199502000-00006","article-title":"Acute and subchronic effects of nefazodone and imipramine on highway driving, cognitive functions and daytime sleepiness in healthy adult and elderly subjects","volume":"15","author":"Van Laar","year":"1995","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB82","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1056\/NEJM198204223061603","article-title":"Cardiovascular effect of tricyclic antidepressants in depressed patients with chronic heart disease","volume":"306","author":"Veith","year":"1982","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/S0306-3623(97)00070-0_BIB83","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1055\/s-2007-1014286","article-title":"Antidepressant drug therapy in the elderly\u2014A critical review of the controlled clinical trials conducted since 1980","volume":"27","author":"Voltz","year":"1994","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB96","doi-asserted-by":"crossref","first-page":"141","DOI":"10.2165\/00003088-199324020-00004","article-title":"Clinical pharmacokinetics of antidepressants in the elderly. Therapeutic implications","volume":"24","author":"Von Moltke","year":"1993","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB84","doi-asserted-by":"crossref","first-page":"41","DOI":"10.2165\/00003088-198712010-00004","article-title":"Plasma protein binding of drugs in the elderly","volume":"12","author":"Wallace","year":"1987","journal-title":"Clin. Phamacokin."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB85","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1001\/archpsyc.1978.01770350030002","article-title":"Affective disorders in a U.S. urban community","volume":"35","author":"Weissman","year":"1978","journal-title":"Arch. Gen. Psych."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB86","first-page":"91","article-title":"The effects of moclobemide on cognition","volume":"28","author":"Wesnes","year":"1989","journal-title":"J. Neural. Transm."},{"key":"10.1016\/S0306-3623(97)00070-0_BIB87","doi-asserted-by":"crossref","unstructured":"West E. D. and Dally P. (1959) Effect of iproniazid on depressive syndromes. Br. Med. J. 1491\u20131494.","DOI":"10.1136\/bmj.1.5136.1491"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB88","doi-asserted-by":"crossref","first-page":"895","DOI":"10.2165\/00003495-199346050-00008","article-title":"Fluvoxamine. An updated review of its pharmacology and therapeutical use in depressive illness","volume":"46","author":"Wilde","year":"1993","journal-title":"Drugs"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB89","doi-asserted-by":"crossref","first-page":"411","DOI":"10.2165\/00003495-199549030-00007","article-title":"Tianeptine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in depression and coexisting anxiety and depression","volume":"49","author":"Wilde","year":"1995","journal-title":"Drugs"},{"key":"10.1016\/S0306-3623(97)00070-0_BIB90","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1600-0447.1990.tb05343.x","article-title":"Interaction studies with moclobemide","volume":"82","author":"Zimmer","year":"1990","journal-title":"Acta Psychiatr. Scand."}],"container-title":["General Pharmacology: The Vascular System"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306362397000700?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306362397000700?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T07:25:20Z","timestamp":1620631520000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306362397000700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,4]]},"references-count":96,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1998,4]]}},"alternative-id":["S0306362397000700"],"URL":"https:\/\/doi.org\/10.1016\/s0306-3623(97)00070-0","relation":{},"ISSN":["0306-3623"],"issn-type":[{"value":"0306-3623","type":"print"}],"subject":[],"published":{"date-parts":[[1998,4]]}}}