{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T16:42:13Z","timestamp":1771000933777,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[1997,11,1]],"date-time":"1997-11-01T00:00:00Z","timestamp":878342400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gene"],"published-print":{"date-parts":[[1997,11]]},"DOI":"10.1016\/s0378-1119(97)00421-6","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T18:13:42Z","timestamp":1027620822000},"page":"21-29","source":"Crossref","is-referenced-by-count":48,"title":["Cloning and characterization of CneMDR1: a Cryptococcus neoformans gene encoding a protein related to multidrug resistance proteins"],"prefix":"10.1016","volume":"201","author":[{"given":"Susan J","family":"Thornewell","sequence":"first","affiliation":[]},{"given":"Robert B","family":"Peery","sequence":"additional","affiliation":[]},{"given":"Paul L","family":"Skatrud","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0378-1119(97)00421-6_BIB1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J. Mol. Biol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB2","doi-asserted-by":"crossref","first-page":"4912","DOI":"10.1128\/MCB.14.7.4912","article-title":"Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulence","volume":"14","author":"Chang","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB3","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0092-8674(86)90595-7","article-title":"Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells","volume":"47","author":"Chen","year":"1986","journal-title":"Cell"},{"key":"10.1016\/S0378-1119(97)00421-6_BIB4","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1093\/nar\/12.1Part1.387","article-title":"A comprehensive set of sequence analysis programs for the VAX","volume":"12","author":"Devereux","year":"1984","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB5","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1128\/JCM.32.10.2364-2371.1994","article-title":"Molecular typing of Cryptococcus serotype D clinical isolates","volume":"32","author":"Dromer","year":"1994","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB6","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/BF02603120","article-title":"A multiple sequence alignment using a simplification of the progressive alignment method","volume":"35","author":"Feng","year":"1987","journal-title":"J. Mol. Evol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB7","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1093\/nar\/12.2.857","article-title":"Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs","volume":"12","author":"Kozak","year":"1981","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB8","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1111\/j.1365-2958.1990.tb02034.x","article-title":"The bex locus in encapsulated Haemophilus influenzae: a chromosomal region involved in capsule polysaccharide export","volume":"4","author":"Kroll","year":"1990","journal-title":"Mol. Microbiol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB9","doi-asserted-by":"crossref","first-page":"3973","DOI":"10.1002\/j.1460-2075.1989.tb08580.x","article-title":"Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells","volume":"8","author":"Kuchler","year":"1989","journal-title":"EMBO J."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB10","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1128\/JB.150.3.1414-1421.1982","article-title":"Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice","volume":"150","author":"Kwon-Chung","year":"1982","journal-title":"J. Bacteriol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB11","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1128\/IAI.51.1.218-223.1986","article-title":"Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans","volume":"51","author":"Kwon-Chung","year":"1986","journal-title":"Infect. Immun."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB12","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1128\/IAI.60.2.602-605.1992","article-title":"Genetic association of mating types and virulence in Cryptococcus neoformans","volume":"60","author":"Kwon-Chung","year":"1992","journal-title":"Infect. Immun."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB13","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0022-2836(82)90515-0","article-title":"A simple method for displaying the hydrophobic character of a protein","volume":"157","author":"Kyte","year":"1982","journal-title":"J. Mol. Biol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB14","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1016\/S0021-9258(17)42038-2","article-title":"Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans","volume":"269","author":"Lodge","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB15","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/BF00391811","article-title":"Extrachromosomal genetics of Cephalosporium acremonium","volume":"5","author":"Minuth","year":"1982","journal-title":"Curr. Genet."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB16","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1111\/j.1365-2958.1992.tb01526.x","article-title":"A leptomycin B resistance gene of Schizosaccharomyces pombe encodes a protein similar to the mammalian P-glycoproteins","volume":"6","author":"Nishi","year":"1992","journal-title":"Mol. Microbiol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB17","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1128\/IAI.57.9.2624-2627.1989","article-title":"Separation of chromosomes of Cryptococcus neoformans by pulsed field gel electrophoresis","volume":"57","author":"Perfect","year":"1989","journal-title":"Infect. Immun."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB18","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1128\/JCM.31.12.3305-3309.1993","article-title":"Karyotyping of Cryptococcus neoformans as an epidemiological tool","volume":"31","author":"Perfect","year":"1993","journal-title":"J. Clin. Microbiol."},{"issue":"Suppl 1","key":"10.1016\/S0378-1119(97)00421-6_BIB19","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1093\/clinids\/14.Supplement_1.S54","article-title":"Therapy for cryptococcal menigitis in patients with AIDS","volume":"14","author":"Powderly","year":"1992","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB20","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/BF00352101","article-title":"Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals","volume":"27","author":"Prasad","year":"1995","journal-title":"Curr. Genet."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB21","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3109\/07388558709089387","article-title":"Recombinant DNA in filamentous fungi: progress and prospects","volume":"6","author":"Rambosek","year":"1987","journal-title":"Crit. Rev. Biotechnol."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB22","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1128\/IAI.36.3.1175-1184.1982","article-title":"Phenoloxidase activity and virulence in isogenic strains of Cryptococcus neoformans","volume":"36","author":"Rhodes","year":"1982","journal-title":"Infect. Immun."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB23","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1126\/science.2475911","article-title":"Identification of the cystic fibrosis gene: cloning and characterization of the complementary DNA","volume":"245","author":"Riordan","year":"1989","journal-title":"Science"},{"key":"10.1016\/S0378-1119(97)00421-6_BIB24","unstructured":"Sambrook, J., Fritsch, E.F., Maniatis, T., 1989. Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB25","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/BF00313195","article-title":"Integrative and replicative genetic transformation of Aureobasidium pullulans","volume":"29","author":"Thornewell","year":"1995","journal-title":"Curr. Genet."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB26","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1002\/j.1460-2075.1982.tb01276.x","article-title":"Distantly related sequences in the \u03b1- and \u03b2-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold","volume":"1","author":"Walker","year":"1982","journal-title":"EMBO J."},{"key":"10.1016\/S0378-1119(97)00421-6_BIB27","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1099\/00221287-140-3-543","article-title":"Comparison of the electrophoretic karyotypes and chromosomal location of ten genes in two varieties of Cryptococcus neoformans","volume":"140","author":"Wickes","year":"1994","journal-title":"Microbiology"},{"key":"10.1016\/S0378-1119(97)00421-6_BIB28","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1128\/AAC.36.3.533","article-title":"Construction of a water-soluble form of penicillin-binding protein 2a from a methicillin-resistant Staphylococcus aureus isolate","volume":"36","author":"Wu","year":"1992","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111997004216?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111997004216?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T15:39:52Z","timestamp":1620574792000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111997004216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,11]]},"references-count":28,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[1997,11]]}},"alternative-id":["S0378111997004216"],"URL":"https:\/\/doi.org\/10.1016\/s0378-1119(97)00421-6","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[1997,11]]}}}