{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:19:19Z","timestamp":1779344359246,"version":"3.51.4"},"reference-count":57,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1998,5,1]],"date-time":"1998-05-01T00:00:00Z","timestamp":893980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1998,5,1]],"date-time":"1998-05-01T00:00:00Z","timestamp":893980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":5556,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuron"],"published-print":{"date-parts":[[1998,5]]},"DOI":"10.1016\/s0896-6273(00)80469-9","type":"journal-article","created":{"date-parts":[[2004,6,30]],"date-time":"2004-06-30T08:27:59Z","timestamp":1088584079000},"page":"869-882","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":409,"title":["Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo"],"prefix":"10.1016","volume":"20","author":[{"given":"Andrew R","family":"Calver","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita C","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Ping","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank S","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John K","family":"Heath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christer","family":"Betsholtz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D","family":"Richardson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0896-6273(00)80469-9_BIB1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/361258a0","article-title":"Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons","volume":"361","author":"Barres","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB2","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/0896-6273(94)90305-0","article-title":"Control of oligodendrocyte number in the developing rat optic nerve","volume":"12","author":"Barres","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB3","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0092-8674(92)90531-G","article-title":"Cell death and control of cell survival in the oligodendrocyte lineage","volume":"70","author":"Barres","year":"1992","journal-title":"Cell"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB4","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1002\/neu.480230912","article-title":"Cell death in the oligodendrocyte lineage","volume":"23","author":"Barres","year":"1992","journal-title":"J. Neurobiol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB5","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0960-9822(93)90039-Q","article-title":"Does oligodendrocyte survival depend on axons?","volume":"3","author":"Barres","year":"1993","journal-title":"Curr. Biol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB6","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1242\/dev.120.5.1097","article-title":"A novel role for thyroid hormone, glucocorticoids and retinoic acid in oligodendrocyte development","volume":"120","author":"Barres","year":"1994","journal-title":"Development"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB7","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S0092-8674(00)81270-2","article-title":"PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis","volume":"85","author":"Bostr\u00f6m","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB8","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1242\/jcs.90.4.601","article-title":"The 3T3 cell cycle at low proliferation rates","volume":"90","author":"Brooks","year":"1988","journal-title":"J. Cell Sci"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB9","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1523\/JNEUROSCI.16-06-02064.1996","article-title":"Glial cells are increased proportionally in transgenic optic nerves with increased numbers of axons","volume":"17","author":"Burne","year":"1996","journal-title":"J. Neurosci"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB10","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0896-6273(00)80155-5","article-title":"GGF\/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits differentiation of oligodendrocyte progenitors","volume":"17","author":"Canoll","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB11","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1101\/gad.11.18.2335","article-title":"Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1","volume":"11","author":"Casacchio-Bonefil","year":"1997","journal-title":"Genes Dev"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB12","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/emboj\/16.2.306","article-title":"Accumulation of the cyclin-dependent kinase inhibitor p27\/Kip1 and the timing of oligodendrocyte development","volume":"16","author":"Durand","year":"1997","journal-title":"EMBO J"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB13","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/jnr.490370116","article-title":"Platelet-derived growth factor receptor is expressed by cells in the early oligodendrocyte lineage","volume":"37","author":"Ellison","year":"1994","journal-title":"J. Neurosci. Res"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB14","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0896-6273(90)90308-3","article-title":"Transgenic mice expressing \u03b2-galactosidase in mature neurons under neuron-specific enolase promoter control","volume":"5","author":"Forss-Petter","year":"1990","journal-title":"Neuron"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB15","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/S0896-6273(00)80244-5","article-title":"PDGF mediates a neuron-astrocyte interaction in the developing retina","volume":"17","author":"Fruttiger","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1749-6632.1991.tb15592.x","article-title":"Glial cells in the rat optic nerve; the search for the type-2 astrocyte","volume":"633","author":"Fulton","year":"1991","journal-title":"Ann. NY Acad. Sci"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB17","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1083\/jcb.138.6.1367","article-title":"Cell size control and a cell-intrinsic maturation program in proliferating oligodendrocyte precursor cells","volume":"138","author":"Gao","year":"1997","journal-title":"J. Cell Biol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB18","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0960-9822(06)00060-1","article-title":"Oligodendrocyte precursor cells count time but not cell divisions before differentiation","volume":"7","author":"Gao","year":"1997","journal-title":"Curr. Biol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB19","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1006\/dbio.1993.1269","article-title":"Glial cell mitogens bFGF and PDGF differentially regulate development of O4+GalC\u2212 oligodendrocyte progenitors","volume":"159","author":"Gard","year":"1993","journal-title":"Dev. Biol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB20","doi-asserted-by":"crossref","first-page":"4085","DOI":"10.1242\/dev.122.12.4085","article-title":"Spinal cord oligodendrocytes develop from ventrally-derived progenitor cells that express PDGF alpha-receptors","volume":"122","author":"Hall","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB21","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1242\/dev.122.7.2059","article-title":"Oligodendrocyte progenitors are generated throughout the embryonic mouse brain, but differentiate in restricted foci","volume":"122","author":"Hardy","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB22","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1242\/dev.105.3.595","article-title":"PDGF receptors on cells of the oligodendrocyte-type-2 astrocyte (O-2A) cell lineage","volume":"105","author":"Hart","year":"1989","journal-title":"Development"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB23","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1002\/j.1460-2075.1988.tb02955.x","article-title":"Binding of different dimeric forms of PDGF to human fibroblasts","volume":"7","author":"Heldin","year":"1988","journal-title":"EMBO J"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/dbio.1996.0280","article-title":"Evidence for the existence of at least two timing mechanisms that contribute to oligodendrocyte generation in vitro","volume":"180","author":"Ibarrola","year":"1996","journal-title":"Dev. Biol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB25","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1523\/JNEUROSCI.09-01-00248.1989","article-title":"In situ hybridization analysis of myelin gene transcripts in developing mouse spinal cord","volume":"9","author":"Jordan","year":"1989","journal-title":"J. Neurosci"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB26","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1101\/gad.8.16.1875","article-title":"Mice deficient for PDGF B show renal, cardiovascular and hematological abnormalities","volume":"8","author":"Leve\u00e9n","year":"1994","journal-title":"Genes Dev"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB27","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0896-6273(89)90119-0","article-title":"Neuronal influences on glial progenitor cell development","volume":"3","author":"Levine","year":"1989","journal-title":"Neuron"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB28","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1126\/science.277.5323.242","article-title":"Pericyte loss and microaneurysm formation in platelet-derived growth factor B-chain deficient mice","volume":"277","author":"Lindahl","year":"1997","journal-title":"Science"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB29","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1177\/37.10.2476478","article-title":"Double immunocytochemistry labeling of cell and tissue samples with monoclonal anti-bromodeoxyuridine","volume":"37","author":"Magaud","year":"1989","journal-title":"J. Histochem. Cytochem"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB30","doi-asserted-by":"crossref","first-page":"7035","DOI":"10.1093\/nar\/12.18.7035","article-title":"Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter","volume":"12","author":"Melton","year":"1984","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB31","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0166-2236(96)80036-1","article-title":"Oligodendrocyte origins","volume":"19","author":"Miller","year":"1996","journal-title":"Trends Neurosci"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB32","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1242\/dev.118.2.539","article-title":"PDGF and its receptors in the developing rodent retina and optic nerve","volume":"118","author":"Mudhar","year":"1993","journal-title":"Development"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB33","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/(SICI)1097-4547(19960201)43:3<299::AID-JNR5>3.0.CO;2-E","article-title":"Co-localization of NG2 proteoglycan and PDGF\u03b1 receptor on O2A progenitor cells in the developing rat brain","volume":"43","author":"Nishiyama","year":"1996","journal-title":"J. Neurosci. Res"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB34","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/333560a0","article-title":"Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte\/type-2 astrocyte progenitor cell","volume":"333","author":"Noble","year":"1988","journal-title":"Nature"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB35","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/BF01190834","article-title":"Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population","volume":"18","author":"Nowakowski","year":"1989","journal-title":"J. Neurocytol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB36","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1242\/dev.115.4.1045","article-title":"Platelet-derived growth factor A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo","volume":"115","author":"Orr-Urtreger","year":"1992","journal-title":"Development"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB37","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0962-8924(93)90213-K","article-title":"The oligodendrocyte and its many cellular processes","volume":"3","author":"Pfeiffer","year":"1994","journal-title":"Trends Cell Biol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB38","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3109\/08977199209046409","article-title":"Alternative splicing generates two isoforms of the PDGF A-chain that differ in their ability to associate with the extracellular matrix and to bind heparin in vitro","volume":"7","author":"Pollock","year":"1992","journal-title":"Growth Factors"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB39","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1002\/j.1460-2075.1989.tb03472.x","article-title":"PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial progenitor cells in the developing rat optic nerve","volume":"8","author":"Pringle","year":"1989","journal-title":"EMBO J"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB40","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1006\/dbio.1996.0142","article-title":"Determination of neuroepithelial cell fate","volume":"177","author":"Pringle","year":"1996","journal-title":"Dev. Biol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB41","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1126\/science.2648568","article-title":"Glial cell diversification in the rat optic nerve","volume":"243","author":"Raff","year":"1989","journal-title":"Science"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB42","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/303390a0","article-title":"A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on the culture medium","volume":"303","author":"Raff","year":"1983","journal-title":"Nature"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB43","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0092-8674(85)80101-X","article-title":"Reconstitution of a developmental clock in vitro","volume":"42","author":"Raff","year":"1985","journal-title":"Cell"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB44","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/333562a0","article-title":"Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture","volume":"333","author":"Raff","year":"1988","journal-title":"Nature"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB45","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/0092-8674(88)90392-3","article-title":"A role for platelet-derived growth factor in normal gliogenesis in the central nervous system","volume":"53","author":"Richardson","year":"1988","journal-title":"Cell"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB46","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1159\/000111186","article-title":"Origins of spinal cord oligodendrocytes","volume":"19","author":"Richardson","year":"1997","journal-title":"Dev. Neurosci"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB47","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0092-8674(91)90223-L","article-title":"PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model","volume":"64","author":"Sasahara","year":"1991","journal-title":"Cell"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB48","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1101\/gad.9.10.1149","article-title":"Inhibitors of mammalian G1 cyclin-dependent kinases","volume":"9","author":"Sherr","year":"1995","journal-title":"Genes Dev"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB49","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/jcp.1040910304","article-title":"Cells regulate their proliferation through alterations in transition probability","volume":"91","author":"Shields","year":"1977","journal-title":"J. Cell. Physiol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB50","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1523\/JNEUROSCI.07-09-02737.1987","article-title":"Bipotential glial progenitor cells of the optic nerve express the NG2 proteoglycan","volume":"7","author":"Stallcup","year":"1987","journal-title":"J. Neurosci"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB51","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1073\/pnas.91.1.375","article-title":"Mode of cell proliferation in the developing mouse neocortex","volume":"91","author":"Takahashi","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB52","doi-asserted-by":"crossref","first-page":"6046","DOI":"10.1523\/JNEUROSCI.15-09-06046.1995","article-title":"The cell cycle of the pseudo-stratified ventricular epithelium of the embryonic murine cerebral wall","volume":"15","author":"Takahashi","year":"1995","journal-title":"J. Neurosci"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB53","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/0092-8674(86)90843-3","article-title":"Clonal analysis of oligodendrocyte development in vitro","volume":"44","author":"Temple","year":"1986","journal-title":"Cell"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB54","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1083\/jcb.137.2.459","article-title":"Differentiation and death of premyelinating oligodendrocytes in developing rodent brain","volume":"137","author":"Trapp","year":"1997","journal-title":"J. Cell Biol"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB55","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0092-8674(91)90222-K","article-title":"PDGF A-chain gene is expressed by mammalian neurons during development and in maturity","volume":"64","author":"Yeh","year":"1991","journal-title":"Cell"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB56","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/0896-6273(94)90450-2","article-title":"Embryonic expression of myelin genes","volume":"12","author":"Yu","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/S0896-6273(00)80469-9_BIB57","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1006\/mcne.1995.1003","article-title":"Asynchronous differentiation of clonally related spinal cord oligodendrocytes","volume":"6","author":"Zhang","year":"1995","journal-title":"Mol. Cell. Neurosci"}],"container-title":["Neuron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896627300804699?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896627300804699?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T06:18:54Z","timestamp":1760249934000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896627300804699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,5]]},"references-count":57,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1998,5]]}},"alternative-id":["S0896627300804699"],"URL":"https:\/\/doi.org\/10.1016\/s0896-6273(00)80469-9","relation":{},"ISSN":["0896-6273"],"issn-type":[{"value":"0896-6273","type":"print"}],"subject":[],"published":{"date-parts":[[1998,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo","name":"articletitle","label":"Article Title"},{"value":"Neuron","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/S0896-6273(00)80469-9","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1998 Cell Press. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}