{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T05:11:00Z","timestamp":1779340260266,"version":"3.51.4"},"reference-count":90,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1997,2,1]],"date-time":"1997-02-01T00:00:00Z","timestamp":854755200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Opinion in Immunology"],"published-print":{"date-parts":[[1997,2]]},"DOI":"10.1016\/s0952-7915(97)80163-x","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T10:33:24Z","timestamp":1027593204000},"page":"80-88","source":"Crossref","is-referenced-by-count":83,"title":["Generation, intracellular transport and loading of peptides associated with MHC class I molecules"],"prefix":"10.1016","volume":"9","author":[{"given":"Jens-Oliver","family":"Koopmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcnter J","family":"H\u00e4mmerling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Momburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0952-7915(97)80163-X_BIB1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0092-8674(94)90336-0","article-title":"MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation","volume":"76","author":"Germain","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB2","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1146\/annurev.iy.11.040193.001241","article-title":"Peptides naturally presented by MHC class I molecules","volume":"11","author":"Rammensee","year":"1993","journal-title":"Ann Rev Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB3","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1146\/annurev.bi.64.070195.002335","article-title":"Generation, translocation, and presentation of MHC class I-restricted peptides","volume":"64","author":"Heemels","year":"1995","journal-title":"Annu Rev Biochem"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB4","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1126\/science.7809629","article-title":"A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules","volume":"267","author":"Kovacsovics-Bankowski","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB5","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/1074-7613(95)90067-5","article-title":"Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages","volume":"3","author":"Norbury","year":"1995","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB6","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1084\/jem.183.1.317","article-title":"Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo","volume":"183","author":"Paglia","year":"1996","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB7","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/357375a0","article-title":"Proteolysis, proteasomes and antigen presentation","volume":"357","author":"Goldberg","year":"1992","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB8","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/356443a0","article-title":"HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides","volume":"356","author":"Wei","year":"1992","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB9","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1084\/jem.181.4.1481","article-title":"Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum","volume":"181","author":"Elliott","year":"1995","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB10","doi-asserted-by":"crossref","first-page":"6140","DOI":"10.4049\/jimmunol.154.11.6140","article-title":"An epitope-selective, transporter associated with antigen presentation (TAP)-1\/2-independent antigen-processing pathway allow recognition of the HIV envelope glycoprotein by CD8+ CTL","volume":"154","author":"Hammond","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB11","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/BF00990965","article-title":"Structural features of archaebacterial and eukaryotic proteasomes","volume":"21","author":"Koster","year":"1996","journal-title":"Mol Biol Rep"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BF00990966","article-title":"Molecular biology of proteasomes","volume":"21","author":"Tanaka","year":"1996","journal-title":"Mol Biol Rep"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0952-7915(96)80106-3","article-title":"Processing and delivery of peptides presented by MHC class I molecules","volume":"8","author":"Lehner","year":"1996","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB14","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/0167-5699(96)10051-7","article-title":"Peptide antigen production by the proteasome: complexity provides efficiency","volume":"17","author":"Groettrup","year":"1996","journal-title":"Immunol Today"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB15","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0092-8674(94)90462-6","article-title":"Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules","volume":"78","author":"Rock","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB16","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.4049\/jimmunol.155.4.1767","article-title":"Novel dipeptide aldehydes are proteasome inhibitors and block the MHC-I antigen-processing pathway","volume":"155","author":"Harding","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB17","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1084\/jem.183.4.1569","article-title":"The protease inhibitor, N-acetyl-L-leucyl-L-leucyl-L-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum","volume":"183","author":"Hughes","year":"1996","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB18","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1084\/jem.183.4.1545","article-title":"The requirement for proteasome activity in class I major histocompatibility complex antigen presentation is dictated by the length of preprocessed antigen","volume":"183","author":"Yang","year":"1996","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB19","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1126\/science.7732382","article-title":"Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin","volume":"268","author":"Fenteany","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB20","doi-asserted-by":"crossref","first-page":"3884","DOI":"10.4049\/jimmunol.152.8.3884","article-title":"Proteolytic processing of ovalbumin and \u03b2-galactosidase by the proteasome to yield antigenic peptides","volume":"152","author":"Dick","year":"1994","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB21_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/1074-7613(95)90053-5","article-title":"Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules","volume":"2","author":"Niedermann","year":"1995","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB22","doi-asserted-by":"crossref","first-page":"8572","DOI":"10.1073\/pnas.93.16.8572","article-title":"The proteolytic fragments generated by vertebrate proteasomes: Structural relationships to major histocompatibility complex class I binding peptides","volume":"93","author":"Niedermann","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB23","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1084\/jem.182.6.1865","article-title":"The cleavage preference of the proteasome governs the yield of antigenic peptides","volume":"182","author":"Eggers","year":"1995","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB24","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/0092-8674(91)90037-Y","article-title":"Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighbouring residues in the protein","volume":"66","author":"Del Val","year":"1991","journal-title":"Cell"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB25_1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S1074-7613(00)80488-4","article-title":"A single residue exchange within a viral CTL epitope alters proteasome-mediated degradation resulting in lack of antigen presentation","volume":"5","author":"Ossendorp","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0092-8674(94)90396-4","article-title":"The ubiquitin-proteasome proteolytic pathway","volume":"79","author":"Ciechanover","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB27","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1084\/jem.168.4.1211","article-title":"Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen","volume":"168","author":"Townsend","year":"1988","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB28_1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.4049\/jimmunol.157.2.617","article-title":"Chemical denaturation and modification of ovalbumin alters its dependence on ubiquitin conjugation for class I antigen presentation","volume":"157","author":"Michalek","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB29","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.4049\/jimmunol.155.8.3750","article-title":"Rate of antigen degradation by the ubiquitin-proteasome pathway influences MHC class I presentation","volume":"155","author":"Grant","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB30_1","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/381166a0","article-title":"A role for the proteasome regulator PA28\u03b1 in antigen presentation","volume":"381","author":"Groettrup","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB31_1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0092-8674(00)80097-5","article-title":"Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands","volume":"86","author":"Dick","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB32","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/0092-8674(91)90095-G","article-title":"Uneven tissue distribution of minor histocompatibility proteins versus peptides is caused by MHC expression","volume":"65","author":"Griem","year":"1991","journal-title":"Cell"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB33","doi-asserted-by":"crossref","first-page":"685","DOI":"10.4049\/jimmunol.156.2.683","article-title":"Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies","volume":"156","author":"Sijts","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB34","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF00188611","article-title":"Hypothesis: heat shock proteins transfer peptides during antigen processing and CTL priming","volume":"39","author":"Srivastava","year":"1994","journal-title":"Immunogenetics"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB35","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1021\/bi00175a027","article-title":"Quantitation of the interaction of the immunosuppressant deoxyspergualin and analogs with Hsc70 and Hsp90","volume":"33","author":"Nadeau","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB36","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0952-7915(95)80031-X","article-title":"Supply and transport of peptides presented by class I MHC molecules","volume":"7","author":"Howard","year":"1995","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB37","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/357342a0","article-title":"Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi","volume":"357","author":"Kleijmeer","year":"1992","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB38","doi-asserted-by":"crossref","first-page":"21312","DOI":"10.1074\/jbc.270.36.21312","article-title":"Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses","volume":"270","author":"Russ","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB39","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1126\/science.8342042","article-title":"Selective and ATP-dependent translocation of peptides by the MHC-encoded peptide transporter","volume":"261","author":"Neefjes","year":"1993","journal-title":"Science"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB40","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1126\/science.8266106","article-title":"Peptide translocation by variants of the transporter associated with antigen processing","volume":"262","author":"Heemels","year":"1993","journal-title":"Science"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB41","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1084\/jem.180.5.1591","article-title":"Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling","volume":"180","author":"Roelse","year":"1994","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB42","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1084\/jem.179.2.533","article-title":"Peptide length and sequence specificity of the mouse TAP1\/TAP2 translocator","volume":"179","author":"Schumacher","year":"1994","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB43_1","doi-asserted-by":"crossref","first-page":"3889","DOI":"10.4049\/jimmunol.155.8.3889","article-title":"Characteristics of ATP-dependent peptide transport in isolated microsomes","volume":"155","author":"Yang","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB44","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1084\/jem.179.5.1613","article-title":"Peptide size selection by the major histocompatibility complex-encoded peptide transporter","volume":"179","author":"Momburg","year":"1994","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB45","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/1074-7613(94)90004-3","article-title":"Human transporters associated with antigen processing possess a promiscuous peptide-binding site","volume":"1","author":"Androlewicz","year":"1994","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB46","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S1074-7613(94)80019-7","article-title":"Substrate specificity of allelic variants of the TAP peptide transporter","volume":"1","author":"Heemels","year":"1994","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB47_1","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1002\/eji.1830260809","article-title":"Translocation of long peptides by transporters associated with antigen processing (TAP)","volume":"26","author":"Koopmann","year":"1996","journal-title":"Eur J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB48","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1073\/pnas.91.4.1534","article-title":"A subset of HLA-B27 molecules contains peptides much longer than nonamers","volume":"91","author":"Urban","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB49","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1038\/367648a0","article-title":"Selectivity of MHC-encoded peptide transporters from human, mouse and rat","volume":"367","author":"Momburg","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB50","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1002\/eji.1830250444","article-title":"Analysis of the fine specificity of rat, mouse and human TAP peptide transporters","volume":"25","author":"Neefjes","year":"1995","journal-title":"Eur J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB51","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.4049\/jimmunol.154.3.1273","article-title":"Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences","volume":"154","author":"Neisig","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB52","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1002\/eji.1830250733","article-title":"Restriction of self-antigen presentation to cytolytic T lymphocytes by mouse peptide pumps","volume":"25","author":"Gournier","year":"1995","journal-title":"Eur J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB53","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/1074-7613(94)90091-4","article-title":"A sequential model for peptide binding and transport by the transporters associated with antigen processing","volume":"1","author":"Van Endert","year":"1994","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB54_1","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1084\/jem.182.6.1883","article-title":"The peptide-binding motif for the human transporter associated with antigen processing","volume":"182","author":"Van Endert","year":"1995","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB55","doi-asserted-by":"crossref","first-page":"18512","DOI":"10.1074\/jbc.270.31.18512","article-title":"Requirements for peptide binding to the human transporter associated with antigen processing revealed by peptide scans and complex peptide libraries","volume":"270","author":"Uebel","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB56_1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S1074-7613(00)80680-9","article-title":"The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against carboxy-terminal trimming of peptides in the ER","volume":"4","author":"Powis","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB57","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.4049\/jimmunol.156.4.1661","article-title":"Rat MHC-linked peptide transporter alleles strongly influence peptide binding by HLA-B27 but not B27-associated inflammatory disease","volume":"156","author":"Simmons","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB58","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1002\/eji.1830250808","article-title":"TAP polymorphism does not influence transport of peptide variants in mice and humans","volume":"25","author":"Obst","year":"1995","journal-title":"Eur J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB59","doi-asserted-by":"crossref","first-page":"13004","DOI":"10.1073\/pnas.91.26.13004","article-title":"Transporters from H-2b, H-2d, H-2s, H-2k, and H-2g7 (NOD\/Lt) haplotype translocate similar peptides","volume":"91","author":"Schumacher","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB60_1","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1007\/BF00179402","article-title":"Polymorphic peptide transporters in MHC class I monomorphic Syrian hamster","volume":"42","author":"Lobigs","year":"1995","journal-title":"Immunogenetics"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB61","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/357211a0","article-title":"Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule","volume":"357","author":"Powis","year":"1992","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB62_1","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.4049\/jimmunol.156.5.1756","article-title":"Residues in TAP2 peptide transporters controlling substrate specificity","volume":"156","author":"Momburg","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB63","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1002\/eji.1830260813","article-title":"A point mutation in the human transporter associated with antigen processing (TAP2) alters the peptide transport specificity","volume":"26","author":"Armandola","year":"1996","journal-title":"Eur J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB64","doi-asserted-by":"crossref","first-page":"12716","DOI":"10.1073\/pnas.91.26.12716","article-title":"Characteristics of peptide and major histocompatibility complex class 1\/\u03b22-microglobulin binding to the transporter associated with antigen processing (TAP1 and TAP2)","volume":"91","author":"Androlewicz","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB65_1","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.4049\/jimmunol.156.6.2186","article-title":"Identification of a contact region for peptide on the TAP1 chain of the transporter associated with antigen processing","volume":"156","author":"Nijenhuis","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB66","doi-asserted-by":"crossref","first-page":"5467","DOI":"10.4049\/jimmunol.157.12.5467","article-title":"Multiple regions of the transporter associated with antigen processing (TAP) contribute to its binding site","volume":"157","author":"Nijenhuis","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB67","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1073\/pnas.92.2.341","article-title":"Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigen","volume":"92","author":"Hill","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB68_1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/375411a0","article-title":"Herpes simplex virus turns off the TAP to evade host immunity","volume":"375","author":"Hill","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB69_1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/375415a0","article-title":"A viral inhibitor of peptide transporters for antigen presentation","volume":"375","author":"Fr\u00fch","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB70","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1002\/j.1460-2075.1996.tb00689.x","article-title":"Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus protein ICP47","volume":"15","author":"Ahn","year":"1996","journal-title":"EMBO J"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB71","doi-asserted-by":"crossref","first-page":"3256","DOI":"10.1002\/j.1460-2075.1996.tb00690.x","article-title":"Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP","volume":"15","author":"Tomazin","year":"1996","journal-title":"EMBO J"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB72_1","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1099\/0022-1317-77-9-2287","article-title":"Human cytomegalovirus inhibits peptide translocation into the endoplasmic reticulum for MHC class I assembly","volume":"77","author":"Hengel","year":"1996","journal-title":"J Gen Virol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB73","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1084\/jem.175.6.1653","article-title":"Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both \u03b22-microglobulin and peptide","volume":"175","author":"Degen","year":"1992","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB74","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1084\/jem.180.6.2163","article-title":"An unstable \u03b22-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide","volume":"180","author":"Sugita","year":"1994","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB75","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1002\/j.1460-2075.1996.tb00493.x","article-title":"The molecular chaperone calnexin facilitates folding and assembly of class I histocompatibility molecules","volume":"15","author":"Vassilakos","year":"1996","journal-title":"EMBO J"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB76","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1084\/jem.181.1.327","article-title":"Species-specific differences in chaperone interaction of human and mouse histocompatibility complex class I molecules","volume":"181","author":"N\u00f6\u03b2ner","year":"1995","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB77_1","doi-asserted-by":"crossref","first-page":"4726","DOI":"10.4049\/jimmunol.155.10.4726","article-title":"TAP associates with a unique class I conformation, whereas calnexin associates with multiple class I forms in mouse and man","volume":"155","author":"Carreno","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB78","doi-asserted-by":"crossref","first-page":"143","DOI":"10.4049\/jimmunol.155.1.143","article-title":"MHC class I expression and transport in a calnexin-deficient cell line","volume":"155","author":"Scott","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB79","doi-asserted-by":"crossref","first-page":"29025","DOI":"10.1074\/jbc.270.48.29025","article-title":"Unique expression of the major histocompatibility complex class I proteins in the absence of glucose trimming and calnexin association","volume":"270","author":"Balow","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB80_1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S1074-7613(00)80487-2","article-title":"Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP","volume":"5","author":"Sadasivan","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB81_1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1084\/jem.184.2.337","article-title":"MHC class I molecules form ternary complexes with calnexin and TAP and undergo peptide-regulated interaction with TAP via their extracellular domains","volume":"184","author":"Suh","year":"1996","journal-title":"J Exp Med"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB82","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1038\/368864a0","article-title":"MHC class 1\/\u03b22-microglobulin complexes associate with TAP transporters before peptide binding","volume":"368","author":"Ortmann","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB83","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1126\/science.8191286","article-title":"Interaction of MHC class I molecules with the transporter associated with antigen processing","volume":"264","author":"Suh","year":"1994","journal-title":"Science"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB84","doi-asserted-by":"crossref","DOI":"10.4049\/jimmunol.158.5.2236","article-title":"Prominence of \u03b22-miroglobulin, class I heavy chain conformation, and tapasin in the interactions of class I heavy chain with calreticulin and the transporter associated with antigen processing","author":"Solheim","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB85_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1126\/science.270.5233.105","article-title":"Dependence of peptide binding by MHC class I molecules on their interaction with ATP","volume":"270","author":"Grandea","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB86","doi-asserted-by":"crossref","first-page":"5525","DOI":"10.4049\/jimmunol.153.12.5525","article-title":"Novel allele-specific, post-translational reduction in HLA class I surface expression in a human B cell line","volume":"153","author":"Greenwood","year":"1994","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB87_1","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.4049\/jimmunol.156.9.3196","article-title":"Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing","volume":"156","author":"Neisig","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB88_1","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S1074-7613(00)80416-1","article-title":"A point mutation in HLA-A*0201 results in failure to bind the TAP complex and to present virus-derived peptides to CTL","volume":"4","author":"Peace-Brewer","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB89_1","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0960-9822(02)00611-5","article-title":"Point mutations in the \u03b12 domain of HLA-A2.1 define a functionally relevant interaction with TAP","volume":"6","author":"Lewis","year":"1996","journal-title":"Curr Biol"},{"key":"10.1016\/S0952-7915(97)80163-X_BIB90_1","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1126\/science.7725097","article-title":"Crystal structure of the 20S proteasome form the archaeon T. acidophilum at 3.4 \u00c5 resolution","volume":"268","author":"L\u00f6we","year":"1995","journal-title":"Science"}],"container-title":["Current Opinion in Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095279159780163X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095279159780163X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T15:37:03Z","timestamp":1680795423000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095279159780163X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,2]]},"references-count":90,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,2]]}},"alternative-id":["S095279159780163X"],"URL":"https:\/\/doi.org\/10.1016\/s0952-7915(97)80163-x","relation":{},"ISSN":["0952-7915"],"issn-type":[{"value":"0952-7915","type":"print"}],"subject":[],"published":{"date-parts":[[1997,2]]}}}