{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:16:16Z","timestamp":1779344176240,"version":"3.51.4"},"reference-count":63,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1996,2,1]],"date-time":"1996-02-01T00:00:00Z","timestamp":823132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1996,2,1]],"date-time":"1996-02-01T00:00:00Z","timestamp":823132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["bmn.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Genetics &amp; Development"],"published-print":{"date-parts":[[1996,2]]},"DOI":"10.1016\/s0959-437x(96)90011-8","type":"journal-article","created":{"date-parts":[[2004,5,15]],"date-time":"2004-05-15T06:35:24Z","timestamp":1084602924000},"page":"56-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":305,"title":["Cdk inhibitors in development and cancer"],"prefix":"10.1016","volume":"6","author":[{"given":"J.","family":"Wade Harper","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen J.","family":"Elledge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0959-437X(96)90011-8_BIB1","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/0092-8674(94)90540-1","article-title":"G1 phase progression: cycling on cue","volume":"79","author":"Sherr","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB2","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/0092-8674(94)90543-6","article-title":"Cyclins and cancer II: cyclin D and CDK Inihibitors come of age","volume":"79","author":"Hunter","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB3","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1126\/science.7997877","article-title":"Cell cycle control and cancer","volume":"266","author":"Hartwell","year":"1994","journal-title":"Science"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB4","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0092-8674(94)90186-4","article-title":"Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle","volume":"79","author":"Peter","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB5","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/0955-0674(94)90055-8","article-title":"Cdk inhibitors: on the threshold of checkpoints and developments","volume":"6","author":"Elledge","year":"1994","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB6","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1101\/gad.9.10.1149","article-title":"Inhibitors of mammalian G1 cyclin-dependent kinases","volume":"9","author":"Sherr","year":"1995","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB7","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/0092-8674(93)90499-G","article-title":"The 21 kd Cdk interacting protein Clp1 is a potent inhibitor of G1 cyclin-dependent kinases","volume":"75","author":"Harper","year":"1993","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB8","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/366701a0","article-title":"p21 is a universal inhibitor of cyclin kinases","volume":"366","author":"Xiong","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB9","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/0092-8674(93)90500-P","article-title":"WAF1, a potential mediator of p53 tumor suppression","volume":"75","author":"El-Deiry","year":"1993","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB10","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1006\/excr.1994.1063","article-title":"Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen","volume":"211","author":"Noda","year":"1994","journal-title":"Exp Cell Res"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0092-8674(94)90573-8","article-title":"p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21","volume":"78","author":"Totoshima","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB12","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0092-8674(94)90572-X","article-title":"Cloning of p27KIP1, a cyclin-dependent kinase inhibitor and potential mediator of extracellular antimitogenic signals","volume":"78","author":"Polyak","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB13_1","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1101\/gad.9.6.650","article-title":"p57KIP2, a structurally distinct member of the p21CIP1 Cdk-inhibitor family, is a candidate tumor suppressor gene","volume":"9","author":"Matsuoka","year":"1995","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB14_1","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1101\/gad.9.6.639","article-title":"Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution","volume":"9","author":"Lee","year":"1995","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB15_1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1091\/mbc.6.4.387","article-title":"Inhibition of cyclin-dependent kinases by p21","volume":"6","author":"Harper","year":"1995","journal-title":"Mol Biol Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB16","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/375159a0","article-title":"Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1","volume":"375","author":"Luo","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB17","first-page":"2281","article-title":"Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor","volume":"10","author":"Goubin","year":"1995","journal-title":"Oncogene"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB18_1","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1101\/gad.9.14.1740","article-title":"p107 uses a p21CIP1 related domain to bind cyclin\/cdk2 and regulates interactions with E2F","volume":"9","author":"Zhu","year":"1995","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB19","first-page":"8655","article-title":"Cdk-interacting protein 1 directly binds with PCNA and inhibits replication catalyzed by the DNA polymerase d holoenzyme","volume":"91","author":"Flores-Rozas","year":"1994"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB20_1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0960-9822(95)00058-3","article-title":"A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen","volume":"5","author":"Warbrick","year":"1995","journal-title":"Curr Biol"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB21","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/369574a0","article-title":"The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA","volume":"369","author":"Waga","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB22_1","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1101\/gad.8.15.1750","article-title":"p21-containing cyclin kinases exist in both active and inactive states","volume":"8","author":"Zhang","year":"1994","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB23_1","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1126\/science.7624798","article-title":"Role of the ubiquitin-proteosome pathway in regulating the abundance of the cyclin-dependent kinase inhibitor p27","volume":"269","author":"Pagano","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB24","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/366704a0","article-title":"A new regulatory motif in cell cycle control causing specific inhibition of cyclin D\/CDK4","volume":"366","author":"Serrano","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB25_1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/371257a0","article-title":"p15INK4B is a potential effector of TGF-\u03b2 induced cell cycle arrest","volume":"371","author":"Hannon","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB26","first-page":"6353","article-title":"Deletion of p16 and p15 genes in brain tumors","volume":"54","author":"Jen","year":"1994","journal-title":"Cancer Res"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB27_1","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1101\/gad.8.24.2939","article-title":"Growth suppression by p18, a p16INK4\/MTS1 and p14INK4B\/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function","volume":"8","author":"Guan","year":"1994","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB28_1","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1128\/MCB.15.5.2672","article-title":"Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin dependent kinases Cdk4 and Cdk6","volume":"15","author":"Hirai","year":"1995","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB29_1","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1128\/MCB.15.5.2682","article-title":"Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4","volume":"15","author":"Chan","year":"1995","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB30_1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/ng0994-15","article-title":"Germline p16 mutations in familial melanoma","volume":"8","author":"Hussussian","year":"1994","journal-title":"Nature Genet"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB31_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/ng0994-22","article-title":"Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus","volume":"8","author":"Kamb","year":"1994","journal-title":"Nature Genet"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB32","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0960-9822(95)00009-1","article-title":"Lessons in p16 from phylum Falconium","volume":"5","author":"Sheaff","year":"1995","journal-title":"Curr Biol"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB33_1","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1038\/375506a0","article-title":"Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition","volume":"375","author":"Koh","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB34_1","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/375503a0","article-title":"Retinoblastoma protein-dependent cell-cycle inhibition by the tumour suppressor p16","volume":"375","author":"Lukas","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB35","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1091\/mbc.6.9.1197","article-title":"Redistribution of the CDK inhibitor p27 between different cyclin-CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation","volume":"6","author":"Poon","year":"1995","journal-title":"Mol Biol Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB36","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1101\/gad.9.15.1831","article-title":"Klp\/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF\u03b2","volume":"9","author":"Reynisdottir","year":"1995","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB37","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/bies.950170606","article-title":"Tumor suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage","volume":"17","author":"Cox","year":"1995","journal-title":"Bioessays"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB38_1","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1126\/science.7871434","article-title":"A p53-dependent mouse spindle checkpoint","volume":"267","author":"Cross","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB39","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/362847a0","article-title":"p53 is required for radiation-induced apoptosis in mouse thymocytes","volume":"362","author":"Lowe","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB40","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1038\/362849a0","article-title":"Thymocyte apoptosis induced by p53-dependent and independent pathways","volume":"362","author":"Clarke","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB41","first-page":"1169","article-title":"WAF1\/CIP1 is induced in p53 mediated G1 arrest and apoptosis","volume":"4","author":"El-Deiry","year":"1994","journal-title":"Cancer Res"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB42","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/0092-8674(94)90379-4","article-title":"p53-dependent inhibition of cyclin dependent kinase activities in human fibroblasts during radiation-induced G1 arrest","volume":"76","author":"Dulic","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB43_1","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0092-8674(95)90039-X","article-title":"Mice lacking p21CIP1\/WAF1 undergo normal development, but are defective in G1 checkpoint control","volume":"82","author":"Deng","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB44","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.1182\/blood.V84.11.3781.bloodjournal84113781","article-title":"Absence of WAF1 mutations in a variety of human malignancies","volume":"84","author":"Shiohara","year":"1994","journal-title":"Blood"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB45_1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/376358a0","article-title":"Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation","volume":"376","author":"Terada","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB46_1","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1126\/science.7863329","article-title":"p53-independent Expression of p21Clp1 in muscle and other terminally differentiating cells","volume":"267","author":"Parker","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB47_1","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1101\/gad.9.8.935","article-title":"p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage","volume":"9","author":"Macleod","year":"1995","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB48_1","first-page":"2910","article-title":"Topological control of p21WAF1\/CIP1 expression in normal and neoplastic tissues","volume":"55","author":"El-Deiry","year":"1995","journal-title":"Cancer Res"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB49","first-page":"3389","article-title":"Induction of p21 (WAF1\/CIP1) during differentiation","volume":"9","author":"Steinman","year":"1994","journal-title":"Oncogene"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB50","first-page":"3397","article-title":"Induction of differentiation in human promyelocytic HL60 leukemia cells activates p21WAF1\/CIP1 expression in the absence of p53","volume":"9","author":"Jiang","year":"1994","journal-title":"Oncogene"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB51_1","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1126\/science.7863327","article-title":"Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD","volume":"267","author":"Halevy","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB52","first-page":"3397","article-title":"Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF\/CIP1, expression in the absence of p53","volume":"9","author":"Jiang","year":"1994","journal-title":"Oncogene"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB53","first-page":"3389","article-title":"Induction of p21 (WAF-1\/CIP1) during differentiation","volume":"9","author":"Steinman","year":"1994","journal-title":"Oncogene"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB54_1","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1126\/science.7863328","article-title":"Inhibition of myogenic differentiation in proliferating myoblast by cyclin D1-dependent kinase","volume":"267","author":"Skapek","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB55_1","first-page":"5259","article-title":"Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators","volume":"14","author":"Rao","year":"1994","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB56_1","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/0092-8674(95)90034-9","article-title":"Cyclin D1 provides a link between development and oncogenesis in the retina and the breast","volume":"82","author":"Sicinski","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB57","first-page":"1395","article-title":"Somatic mutations of the WAF1\/CIP1 gene in primary prostate cancer","volume":"11","author":"Gao","year":"1995","journal-title":"Oncogene"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB58","first-page":"1206","article-title":"Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias","volume":"55","author":"Pietenpol","year":"1995","journal-title":"Cancer Res"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB59","unstructured":"Ponce-Castaneda, M.V., Lee, M.H., Latres, E., Polyak, K., Lacombe, L., Montgomery, K., Mathew, S., Kraufer, K., Sheinfeld, J., Massagu\u00e9, J., Cordon-Cardo, C., p27Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res 55:1211\u20131214."},{"key":"10.1016\/S0959-437X(96)90011-8_BIB60","first-page":"5545","article-title":"Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53 independent mechanism","volume":"92","author":"Datto","year":"1995"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB61","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/372570a0","article-title":"Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin","volume":"372","author":"Nourse","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB62","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/0092-8674(94)90257-7","article-title":"Cyclic AMP-induced G1 phase arrest mediated by an inhibitor(p27Kip1) of cyclin-dependent kinase 4 activation","volume":"79","author":"Kato","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(96)90011-8_BIB63","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1038\/377552a0","article-title":"Radiation-induced cell cycle arrest compromised by p21 deficiency","volume":"377","author":"Brugarolas","year":"1995","journal-title":"Nature"}],"container-title":["Current Opinion in Genetics &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X96900118?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X96900118?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T11:27:29Z","timestamp":1760700449000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959437X96900118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,2]]},"references-count":63,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,2]]}},"alternative-id":["S0959437X96900118"],"URL":"https:\/\/doi.org\/10.1016\/s0959-437x(96)90011-8","relation":{},"ISSN":["0959-437X"],"issn-type":[{"value":"0959-437X","type":"print"}],"subject":[],"published":{"date-parts":[[1996,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cdk inhibitors in development and cancer","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Genetics & Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/S0959-437X(96)90011-8","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1996 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}