{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:07:44Z","timestamp":1762175264903},"reference-count":69,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1999,10,1]],"date-time":"1999-10-01T00:00:00Z","timestamp":938736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Opinion in Genetics &amp; Development"],"published-print":{"date-parts":[[1999,10]]},"DOI":"10.1016\/s0959-437x(99)00015-5","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T21:44:34Z","timestamp":1027633474000},"page":"566-574","source":"Crossref","is-referenced-by-count":48,"title":["Combinatorial codes in signaling and synergy: lessons from pituitary development"],"prefix":"10.1016","volume":"9","author":[{"given":"Jeremy S","family":"Dasen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G","family":"Rosenfeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0959-437X(99)00015-5_BIB1","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/S0955-0674(96)80085-8","article-title":"The hypothalamic-pituitary axis: co-development of two organs","volume":"8","author":"Treier","year":"1996","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB2","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1101\/gad.12.11.1691","article-title":"Multistep signaling requirements for pituitary organogenesis in vivo","volume":"12","author":"Treier","year":"1998","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB3","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1242\/dev.125.6.1005","article-title":"Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary","volume":"125","author":"Ericson","year":"1998","journal-title":"Development"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB4","doi-asserted-by":"crossref","first-page":"4835","DOI":"10.1242\/dev.125.23.4835","article-title":"Formation of Rathke\u2019s pouch requires dual induction from the diencephalon","volume":"125","author":"Takuma","year":"1998","journal-title":"Development"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB5","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1101\/gad.13.4.388","article-title":"Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning","volume":"13","author":"Karlstrom","year":"1999","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB6","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1073\/pnas.92.7.2720","article-title":"P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1","volume":"92","author":"Bach","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB7","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/aja.1002020405","article-title":"Expression pattern of the murine LIM class homeobox gene Lhx3 in subsets of neural and neuroendocrine tissues","volume":"202","author":"Zhadanov","year":"1995","journal-title":"Dev Dyn"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB8","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1101\/gad.10.10.1284","article-title":"Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene","volume":"10","author":"Lamonerie","year":"1996","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB9","doi-asserted-by":"crossref","first-page":"7706","DOI":"10.1073\/pnas.93.15.7706","article-title":"P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development","volume":"5","author":"Szeto","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB10","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1101\/gad.13.4.484","article-title":"Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development","volume":"15","author":"Szeto","year":"1999","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB11","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1093\/hmg\/6.3.457","article-title":"Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation","volume":"6","author":"Gage","year":"1997","journal-title":"Hum Mol Genet"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB12","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1210\/me.12.3.428","article-title":"The pan-pituitary activator of transcription Ptx1, (pituitary homeobox 1) acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3\/Lhx3","volume":"12","author":"Tremblay","year":"1998","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB13","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1038\/ng1296-392","article-title":"Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome","volume":"14","author":"Semina","year":"1996","journal-title":"Nat Genet"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB14","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0092-8674(00)81468-3","article-title":"Links in the left\/right axial pathway","volume":"94","author":"Harvey","year":"1998","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB15","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1101\/gad.11.11.1370","article-title":"A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins","volume":"11","author":"Bach","year":"1997","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB16","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/384270a0","article-title":"Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins","volume":"384","author":"Agulnick","year":"1996","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB17","doi-asserted-by":"crossref","first-page":"11693","DOI":"10.1073\/pnas.93.21.11693","article-title":"Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development","volume":"93","author":"Jurata","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB18","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.1101\/gad.11.20.2729","article-title":"Chip, a widely expressed chromosomal protein required for segmentation and activity of a remote wing margin enhancer in Drosophila","volume":"11","author":"Morcillo","year":"1997","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB19","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1126\/science.272.5264.1004","article-title":"Specification of pituitary cell lineages by the LIM homeobox gene Lhx3","volume":"272","author":"Sheng","year":"1996","journal-title":"Science"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB20","doi-asserted-by":"crossref","unstructured":"Lin CR, Koussi C, O\u2019Connell S, Briata P, Szeto D, Liu F, Izpisua-Belmonte JC, Rosenfeld HG: Pitx regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature 1999, in press.","DOI":"10.1038\/45803"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB21","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1126\/science.278.5344.1809","article-title":"Multistep control of pituitary organogenesis","volume":"278","author":"Sheng","year":"1997","journal-title":"Science"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB22","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1242\/dev.126.9.1805","article-title":"Hindlimb patterning and mandible development require the Ptx1 gene","volume":"29","author":"Lanctot","year":"1999","journal-title":"Development"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB23","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0888-7543(91)90430-M","article-title":"Localization of the panhypopituitary dwarf mutation (df) on mouse chromosome 11 in an intersubspecific backcross","volume":"10","author":"Buckwalter","year":"1991","journal-title":"Genomics"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB24","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1242\/dev.122.1.151","article-title":"Anterior pituitary cells defective in the cell-autonomous factor, df, undergo cell lineage specification but not expansion","volume":"122","author":"Gage","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB25","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1006\/dbio.1995.8040","article-title":"The Ames dwarf gene is required for Pit-1 gene activation","volume":"172","author":"Andersen","year":"1995","journal-title":"Dev Biol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB26","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/384327a0","article-title":"Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism","volume":"384","author":"Sornson","year":"1996","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB27","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1210\/me.10.12.1570","article-title":"The Ames dwarf gene, df, is required early in pituitary ontogeny for the extinction of Rpx transcription and initiation of lineage-specific cell proliferation","volume":"10","author":"Gage","year":"1996","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB28","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/ng0298-147","article-title":"Mutations in PROP1 cause familial combined pituitary hormone deficiency","volume":"18","author":"Wu","year":"1998","journal-title":"Nat Genet"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB29","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1242\/dev.122.10.3141","article-title":"A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo","volume":"122","author":"Smith","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB30","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1242\/dev.122.1.41","article-title":"Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke\u2019s pouch of the mouse embryo","volume":"122","author":"Hermesz","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB31","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/477","article-title":"Mutations in the homeobox gene HESX1\/Hesx1 associated with septo-optic dysplasia in human and mouse","volume":"19","author":"Dattani","year":"1998","journal-title":"Nat Genet"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB32","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/382357a0","article-title":"BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.1","volume":"382","author":"Mead","year":"1996","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB33","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/0092-8674(88)90038-4","article-title":"A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype","volume":"55","author":"Ingraham","year":"1988","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB34","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0092-8674(88)90037-2","article-title":"The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein","volume":"55","author":"Bodner","year":"1988","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB35","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1038\/347528a0","article-title":"Dwarf locus mutants lacking three pituitary cell-types result from mutations in the POU-domain gene pit-1","volume":"347","author":"Li","year":"1990","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB36","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1101\/gad.3.7.959","article-title":"Cell-specific expression of the prolactin gene in transgenic mice is controlled by synergistic interactions between promoter and enhancer elements","volume":"3","author":"Crenshaw","year":"1989","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB37","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1101\/gad.4.5.695","article-title":"Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors","volume":"4","author":"Simmons","year":"1990","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB38","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1210\/me.11.6.674","article-title":"Role of estrogen receptor-alpha in the anterior pituitary gland","volume":"11","author":"Scully","year":"1997","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB39","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1128\/MCB.17.3.1065","article-title":"Interaction of Ets-1 and the POU-homeodomain protein GHF-1\/Pit-1 reconstitutes pituitary-specific gene expression","volume":"17","author":"Bradford","year":"1997","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB40","doi-asserted-by":"crossref","first-page":"20930","DOI":"10.1074\/jbc.270.36.20930","article-title":"A composite Ets\/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways","volume":"270","author":"Howard","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB41","doi-asserted-by":"crossref","first-page":"31909","DOI":"10.1074\/jbc.273.48.31909","article-title":"Selective inhibition of prolactin gene transcription by the ETS-2 repressor factor","volume":"273","author":"Day","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB42","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1101\/gad.7.9.1674","article-title":"Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression","volume":"7","author":"Lipkin","year":"1993","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB43","doi-asserted-by":"crossref","first-page":"27541","DOI":"10.1074\/jbc.273.42.27541","article-title":"Role of GHF-1 in the regulation of the rat growth hormone gene promoter by thyroid hormone and retinoic acid receptors","volume":"273","author":"Palomino","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB44","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1210\/me.6.4.656","article-title":"Synergistic activation of the rat growth hormone promoter by Pit-1 and the thyroid hormone receptor","volume":"6","author":"Schaufele","year":"1992","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB45","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1101\/gad.13.10.1329","article-title":"Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation","volume":"13","author":"Gothe","year":"1999","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB46","doi-asserted-by":"crossref","first-page":"10655","DOI":"10.1073\/pnas.95.18.10655","article-title":"DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression","volume":"95","author":"Bennani-Baiti","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB47","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1101\/gad.11.2.198","article-title":"Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility","volume":"11","author":"Jacobson","year":"1997","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB48","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0092-8674(00)80770-9","article-title":"Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient induced determination of pituitary cell types","volume":"97","author":"Dasen","year":"1999","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB49","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/371221a0","article-title":"An early haematopoietic defect in mice lacking the transcription factor GATA-2","volume":"371","author":"Tsai","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB50","doi-asserted-by":"crossref","first-page":"5592","DOI":"10.1128\/MCB.14.8.5592","article-title":"GATA-binding proteins regulate the human gonadotropin alpha-subunit gene in the placenta and pituitary gland","volume":"8","author":"Steger","year":"1994","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB51","doi-asserted-by":"crossref","first-page":"24339","DOI":"10.1074\/jbc.272.39.24339","article-title":"Pit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin beta-subunit promoter","volume":"272","author":"Gordon","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB52","doi-asserted-by":"crossref","first-page":"5687","DOI":"10.1093\/emboj\/16.18.5687","article-title":"The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors","volume":"16","author":"Durocher","year":"1997","journal-title":"EMBO J"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB53","doi-asserted-by":"crossref","first-page":"8231","DOI":"10.1074\/jbc.274.12.8231","article-title":"Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx\/Nkx-2.5 and GATA-4","volume":"274","author":"Shiojima","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB54","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0092-8674(00)81183-6","article-title":"DNA binding of the glucocorticoid receptor is not essential for survival","volume":"93","author":"Reichardt","year":"1998","journal-title":"Cell"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB55","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1101\/gad.8.19.2302","article-title":"The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis","volume":"8","author":"Ingraham","year":"1994","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB56","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1126\/science.273.5279.1219","article-title":"Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)","volume":"273","author":"Lee","year":"1996","journal-title":"Science"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB57","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1128\/MCB.19.4.2567","article-title":"Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription","volume":"19","author":"Tremblay","year":"1999","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB58","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1210\/me.12.1.107","article-title":"Multiple pituitary and ovarian defects in Krox-24 (NGFI-A, Egr-1)-targeted mice","volume":"12","author":"Topilko","year":"1998","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB59","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1210\/mend-5-12-2025","article-title":"Targeted ablation of pituitary gonadotropes in transgenic mice","volume":"5","author":"Kendall","year":"1991","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB60","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1210\/me.12.5.622","article-title":"Cell-specific expression of the mouse glycoprotein hormone alpha-subunit gene requires multiple interacting DNA elements in transgenic mice and cultured cells","volume":"12","author":"Brinkmeier","year":"1998","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB61","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1210\/me.8.10.1420","article-title":"Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland","volume":"8","author":"Kendall","year":"1994","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB62","doi-asserted-by":"crossref","first-page":"15526","DOI":"10.1074\/jbc.274.22.15526","article-title":"An upstream regulator of the glycoprotein hormone alpha-subunit gene mediates pituitary cell type activation and repression by different mechanisms","volume":"274","author":"Wood","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB63","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1101\/gad.7.6.913","article-title":"A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene","volume":"7","author":"Rhodes","year":"1993","journal-title":"Genes Dev"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB64","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1006\/dbio.1996.8472","article-title":"The Pit-1 gene is regulated by distinct early and late pituitary-specific enhancers","volume":"182","author":"DiMattia","year":"1997","journal-title":"Dev Biol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB65","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1210\/me.13.3.476","article-title":"Defective retinoic acid regulation of the Pit-1 gene enhancer: a novel mechanism of combined pituitary hormone deficiency","volume":"13","author":"Cohen","year":"1999","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB66","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1210\/me.12.11.1708","article-title":"Pituitary-directed leukemia inhibitory factor transgene causes Cushing\u2019s syndrome: neuro-immune-endocrine modulation of pituitary development","volume":"12","author":"Yano","year":"1998","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB67","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/26270","article-title":"Signal-specific co-activator domain requirements for Pit-1 activation","volume":"395","author":"Xu","year":"1998","journal-title":"Nature"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB68","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1210\/me.13.2.268","article-title":"A novel mechanism for cyclic adenosine 3\u2032,5\u2032-monophosphate regulation of gene expression by CREB-binding protein","volume":"13","author":"Zanger","year":"1999","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0959-437X(99)00015-5_BIB69","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/S0959-437X(99)80021-5","article-title":"Coactivator and corepressor complexes in nuclear receptor function","volume":"9","author":"Xu","year":"1999","journal-title":"Curr Opin Genet Dev"}],"container-title":["Current Opinion in Genetics &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X99000155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X99000155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T23:19:27Z","timestamp":1620947967000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959437X99000155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,10]]},"references-count":69,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1999,10]]}},"alternative-id":["S0959437X99000155"],"URL":"https:\/\/doi.org\/10.1016\/s0959-437x(99)00015-5","relation":{},"ISSN":["0959-437X"],"issn-type":[{"type":"print","value":"0959-437X"}],"subject":[],"published":{"date-parts":[[1999,10]]}}}