{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T08:10:58Z","timestamp":1776240658389,"version":"3.50.1"},"reference-count":54,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1997,2,1]],"date-time":"1997-02-01T00:00:00Z","timestamp":854755200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Opinion in Neurobiology"],"published-print":{"date-parts":[[1997,2]]},"DOI":"10.1016\/s0959-4388(97)80123-7","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T10:33:24Z","timestamp":1027593204000},"page":"75-80","source":"Crossref","is-referenced-by-count":165,"title":["The Eph family in retinal axon guidance"],"prefix":"10.1016","volume":"7","author":[{"given":"Uwe","family":"Drescher","sequence":"first","affiliation":[]},{"given":"Friedrich","family":"Bonhoeffer","sequence":"additional","affiliation":[]},{"given":"Bernhard K","family":"M\u00fcller","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0959-4388(97)80123-7_BIB1","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1002\/neu.480241011","article-title":"Position, guidance, and mapping in the developing visual system","volume":"24","author":"Holt","year":"1993","journal-title":"J Neurobiol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB2","first-page":"673","article-title":"Development of the visual system of the chick \u2014 a review","volume":"33","author":"Mey","year":"1992","journal-title":"J Hirnforsch"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB3","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev.ne.11.030188.001445","article-title":"Formation of topographic maps","volume":"11","author":"Udin","year":"1988","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB4","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1146\/annurev.ne.19.030196.002013","article-title":"Mechanisms and molecules that control growth cone guidance","volume":"19","author":"Goodman","year":"1996","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB5","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1242\/dev.101.4.685","article-title":"Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro","volume":"101","author":"Walter","year":"1987","journal-title":"Development"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB6","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1523\/JNEUROSCI.07-01-00201.1987","article-title":"Collapse of growth cone structure on contact with specific neurites in culture","volume":"7","author":"Kapfhammer","year":"1987","journal-title":"J Neurosci"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB7","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0896-6273(90)90441-H","article-title":"Axonal guidance in the chick visual system: posterior tectal membranes induce collapse of growth cones from the temporal retina","volume":"2","author":"Cox","year":"1990","journal-title":"Neuron"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB8","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0092-8674(95)90425-5","article-title":"In-vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases","volume":"82","author":"Drescher","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB9","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0092-8674(95)90426-3","article-title":"Complementary gradients in expression and binding of elf-1 and mek4 in development of the topographic retinotectal projection map","volume":"82","author":"Cheng","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB10","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1006\/mcne.1995.0001","article-title":"Telling axons where to grow: a role for Eph receptor tyrosine kinases in guidance","volume":"6","author":"Brambilla","year":"1995","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB11","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/S0960-9822(95)00195-3","article-title":"Receptor orphans find a family","volume":"5","author":"Pandey","year":"1995","journal-title":"Curr Biol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB12","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0959-4388(96)80018-3","article-title":"Eph receptor tyrosine kinases and their ligands in neural development","volume":"6","author":"Friedman","year":"1996","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB13","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0959-437X(96)80069-4","article-title":"Novel gene families involved in neural pathfinding","volume":"6","author":"M\u00fcller","year":"1996","journal-title":"Curr Opin Genet Dev"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB14","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0960-9822(02)00435-9","article-title":"Axon guidance: following the Eph plan","volume":"6","author":"Orike","year":"1996","journal-title":"Curr Biol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB15_1","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0092-8674(00)80150-6","article-title":"Topographic specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo","volume":"86","author":"Nakamoto","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB16_1","doi-asserted-by":"crossref","DOI":"10.1093\/emboj\/16.6.1258","article-title":"Shared and unique functions of RAGS and ELF-1 in guiding retinal axons","author":"Monschau","year":"1997","journal-title":"EMBO J"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB17","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0378-1119(94)90692-0","article-title":"Identification of a complete cek7 receptor protein-tyrosine kinase coding sequence and cDNAs of alternatively spliced transcripts","volume":"148","author":"Siever","year":"1994","journal-title":"Gene"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB18","first-page":"1807","article-title":"Five novel avian Eph-related tyrosine kinases are differentially expressed","volume":"8","author":"Sajjadi","year":"1993","journal-title":"Oncogene"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB19_1","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/S0960-9822(02)00645-0","article-title":"Rostral optic tectum acquires caudal characteristics following ectopic Engrailed expression","volume":"6","author":"Logan","year":"1996","journal-title":"Curr Biol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB20_1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0896-6273(00)80023-9","article-title":"A role for gradient en expression in positional specification on the optic tectum","volume":"16","author":"Itasaki","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB21_1","doi-asserted-by":"crossref","first-page":"5498","DOI":"10.1523\/JNEUROSCI.16-17-05498.1996","article-title":"Retroviral misexpression of engrailed genes in the optic tectum perturbs the topographic targeting of retinal axons","volume":"16","author":"Friedman","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB22","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0168-9525(96)81383-7","article-title":"Engrailed, wnt and pax genes regulate midbrain-hindbrain development","volume":"12","author":"Joyner","year":"1996","journal-title":"Trends Genet"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB23","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1242\/dev.110.2.331","article-title":"Rotation of the tectal primordium reveals plasticity of target recognition in retinotectal projection","volume":"110","author":"Ichijo","year":"1990","journal-title":"Development"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB24","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1242\/dev.113.4.1133","article-title":"Establishment of rostrocaudal polarity in tectal primordium: engrailed expression and subsequent tectal polarity","volume":"113","author":"Itasaki","year":"1991","journal-title":"Development"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB25","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/0896-6273(92)90099-Y","article-title":"Rostrocaudal polarity of the tectum in birds: correlation of en gradient and topographic order in retinotectal projection","volume":"8","author":"Itasaki","year":"1992","journal-title":"Neuron"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB26","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1002\/j.1460-2075.1991.tb07663.x","article-title":"Active repression of the transcription by the engrailed homeodomain protein","volume":"10","author":"Jaynes","year":"1991","journal-title":"EMBO J"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB27","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1126\/science.7624797","article-title":"Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2","volume":"269","author":"Hanks","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB28","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0896-6273(93)90325-L","article-title":"Guidance and topographic stabilization of nasal chick retinal axons on target-derived components in vitro","volume":"10","author":"Von Boxberg","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB29","first-page":"77","article-title":"Developmental mechanisms that generate precise patterns of neuronal connectivity","volume":"10","author":"Goodman","year":"1994","journal-title":"Cell\/Neuron"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB30","doi-asserted-by":"crossref","first-page":"5106","DOI":"10.1523\/JNEUROSCI.16-16-05106.1996","article-title":"Retinal ganglion cell axons recognize specific guidance cues present in the deafferented adult rat superior colliculus","volume":"16","author":"Baehr","year":"1996","journal-title":"J Neurosci"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB31","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1006\/dbio.1995.8039","article-title":"Polarized expression of the receptor protein tyrosine kinase Cek5 in the developing avian visual system","volume":"172","author":"Holash","year":"1995","journal-title":"Dev Biol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB32","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1006\/dbio.1995.8083","article-title":"The receptor tyrosine kinase cek5 mRNA is expressed in a gradient within the neural retina and the tectum","volume":"172","author":"Kenny","year":"1995","journal-title":"Dev Biol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB33","article-title":"Developmental expression and distinctive tyrosine phosphorylation of the Eph-related receptor tyrosine kinase Cek9","author":"Soans","year":"1996","journal-title":"Oncogene"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB34","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0092-8674(00)80075-6","article-title":"Nuk controls pathfinding of commissural axons in the mammalian nervous system","volume":"86","author":"Henkemeyer","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB35","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/379830a0","article-title":"Anterograde transport of neurotrophins and axodendritic transfer in the developing visual system","volume":"379","author":"Von Bartheld","year":"1996","journal-title":"Nature"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB36","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1242\/dev.122.1.195","article-title":"Retinoic acid establishes ventral retinal characteristics","volume":"122","author":"Hyatt","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB37","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1006\/dbio.1995.1226","article-title":"Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2\/EpIg2)","volume":"170","author":"Bouillet","year":"1995","journal-title":"Dev Biol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB38","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0925-4773(96)00539-4","article-title":"Five years on the wings of fork head","volume":"57","author":"Kaufmann","year":"1996","journal-title":"Mech Dev"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB39","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1002\/neu.480251010","article-title":"Expression of winged helix genes, BF1 and BF2, define adjacent domains within the developing forebrain and retina","volume":"25","author":"Hatini","year":"1994","journal-title":"J Neurobiol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB40_1","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/382632a0","article-title":"Visual projection map specified by topographic expression of transcription factors in the retina","volume":"382","author":"Yuasa","year":"1996","journal-title":"Nature"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB41","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1523\/JNEUROSCI.11-05-01470.1991","article-title":"A monoclonal antibody that distinguishes between nasal and temporal retinal axons","volume":"11","author":"McLoon","year":"1991","journal-title":"J Neurosci"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB42","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1073\/pnas.78.4.2145","article-title":"A topographic gradient of molecules in retina can be used to identify cell position","volume":"78","author":"Trisler","year":"1981","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB43","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1242\/jeb.153.1.11","article-title":"Cell recognition and pattern formation in the developing nervous system","volume":"153","author":"Trisler","year":"1990","journal-title":"J Exp Biol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB44","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0896-6273(95)90283-X","article-title":"Molecular cloning of TOPAP: a topographically graded protein in the developing chick visual system","volume":"14","author":"Savitt","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB45","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/0896-6273(90)90227-7","article-title":"Biochemical characterization of a putative axonal guidance molecule of the chick visual system","volume":"5","author":"Stahl","year":"1990","journal-title":"Neuron"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB46","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/S0960-9822(96)00754-3","article-title":"Chromophore-assisted laser inactivation by a repulsive axonal guidance molecule","volume":"6","author":"M\u00fcller","year":"1996","journal-title":"Curr Biol"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB47","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1126\/science.7660128","article-title":"Separation of caveolae from associated microdomains of GPI-anchored proteins","volume":"269","author":"Schnitzer","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB48","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0092-8674(00)81036-3","article-title":"The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila","volume":"84","author":"Krueger","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB49","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0092-8674(00)81035-1","article-title":"Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo","volume":"84","author":"Desai","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB50","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/S0896-6273(00)80131-2","article-title":"PY in the fly: receptor-like tyrosine phosphatases in axonal pathfinding","volume":"16","author":"Chien","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB51","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0092-8674(95)90312-7","article-title":"The carbonic anhydrase domain of receptor tyrosine phosphatase beta is an functional ligand for the axonal recognition molecule contactin","volume":"82","author":"Peles","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB52","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0165-3806(96)83493-6","article-title":"Comparative localisation of CRYP alpha, a CAM-like tyrosine phosphatase, and NgCAM in the developing chick visual system","volume":"90","author":"Stoker","year":"1995","journal-title":"Dev Brain Res"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB53","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0925-4773(95)00461-0","article-title":"The receptor tyrosine kinase, Cek8, is transiently expressed on subtypes of motoneurons in the spinal cord during development","volume":"54","author":"Ohta","year":"1996","journal-title":"Mech Dev"},{"key":"10.1016\/S0959-4388(97)80123-7_BIB54","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1006\/mcne.1996.0005","article-title":"Expression of the tyro4\/mek4\/cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets","volume":"7","author":"Kilpatrick","year":"1996","journal-title":"Mol Cell Neurosci"}],"container-title":["Current Opinion in Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959438897801237?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959438897801237?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T12:59:20Z","timestamp":1620133160000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959438897801237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,2]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,2]]}},"alternative-id":["S0959438897801237"],"URL":"https:\/\/doi.org\/10.1016\/s0959-4388(97)80123-7","relation":{},"ISSN":["0959-4388"],"issn-type":[{"value":"0959-4388","type":"print"}],"subject":[],"published":{"date-parts":[[1997,2]]}}}