{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T01:07:08Z","timestamp":1767834428132,"version":"3.49.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"16","license":[{"start":{"date-parts":[[2001,8,1]],"date-time":"2001-08-01T00:00:00Z","timestamp":996624000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4368,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Biology"],"published-print":{"date-parts":[[2001,8]]},"DOI":"10.1016\/s0960-9822(01)00370-0","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T17:18:16Z","timestamp":1027617496000},"page":"1266-1271","source":"Crossref","is-referenced-by-count":91,"title":["MAPK specificity in the yeast pheromone response independent of transcriptional activation"],"prefix":"10.1016","volume":"11","author":[{"given":"Ashton","family":"Breitkreutz","sequence":"first","affiliation":[]},{"given":"Lorrie","family":"Boucher","sequence":"additional","affiliation":[]},{"given":"Mike","family":"Tyers","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0960-9822(01)00370-0_BIB1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0168-9525(98)01425-5","article-title":"The riddle of MAP kinase signaling specificity","volume":"14","author":"Madhani","year":"1998","journal-title":"Trends Genet"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB2","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0092-8674(00)80454-7","article-title":"MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation","volume":"91","author":"Madhani","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB3","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/0092-8674(90)90503-7","article-title":"Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast","volume":"63","author":"Chang","year":"1990","journal-title":"Cell"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB4","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1126\/science.282.5393.1511","article-title":"The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating","volume":"282","author":"Butty","year":"1998","journal-title":"Science"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB5","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1128\/MMBR.62.4.1264-1300.1998","article-title":"MAP kinase pathways in the yeast Saccharomyces cerevisiae","volume":"62","author":"Gustin","year":"1998","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0092-8674(95)90402-6","article-title":"MAP kinase pathways in yeast","volume":"80","author":"Herskowitz","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB7","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1101\/gad.12.17.2684","article-title":"Membrane recruitment of the kinase cascade scaffold protein Ste5 by the G\u03b2\u03b3 complex underlies activation of the yeast pheromone response pathway","volume":"12","author":"Pryciak","year":"1998","journal-title":"Genes Dev"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB8","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0960-9822(98)70108-3","article-title":"Functional binding between G\u03b2 and the LIM domain of Ste5 is required to activate the MEKK Ste11","volume":"8","author":"Feng","year":"1998","journal-title":"Curr Biol"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB9","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0092-8674(94)90427-8","article-title":"Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae","volume":"78","author":"Choi","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/34448","article-title":"Interaction of a G-protein beta-subunit with a conserved sequence in Ste20\/PAK family protein kinases","volume":"391","author":"Leeuw","year":"1998","journal-title":"Nature"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB11","doi-asserted-by":"crossref","first-page":"7559","DOI":"10.1128\/MCB.20.20.7559-7571.2000","article-title":"Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae","volume":"20","author":"Moskow","year":"2000","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB12","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1101\/gad.5.5.741","article-title":"Pheromone-dependent phosphorylation of the yeast STE12 protein correlates with transcriptional activation","volume":"5","author":"Song","year":"1991","journal-title":"Genes Dev"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB13","doi-asserted-by":"crossref","first-page":"2831","DOI":"10.1101\/gad.10.22.2831","article-title":"Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae","volume":"10","author":"Cook","year":"1996","journal-title":"Genes Dev"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB14","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0960-9822(06)00118-7","article-title":"Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates","volume":"7","author":"Tedford","year":"1997","journal-title":"Curr Biol"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB15","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1126\/science.287.5454.873","article-title":"Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles","volume":"287","author":"Roberts","year":"2000","journal-title":"Science"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB16","doi-asserted-by":"crossref","first-page":"5659","DOI":"10.1128\/MCB.13.9.5659","article-title":"Far1 and Fus3 link the mating pheromone signal transduction pathway to three G1-phase Cdc28 kinase complexes","volume":"13","author":"Tyers","year":"1993","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB17","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/0092-8674(93)90254-N","article-title":"FAR1 links the signal transduction pathway to the cell cycle machinery in yeast","volume":"73","author":"Peter","year":"1993","journal-title":"Cell"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB18","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1126\/science.8259520","article-title":"Elements of the yeast pheromone response pathway required for filamentous growth of diploids","volume":"262","author":"Liu","year":"1993","journal-title":"Science"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB19","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1101\/gad.8.24.2974","article-title":"Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type","volume":"8","author":"Roberts","year":"1994","journal-title":"Genes Dev"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB20","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1101\/gad.6.7.1280","article-title":"Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1","volume":"6","author":"Gartner","year":"1992","journal-title":"Genes Dev"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB21","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1091\/mbc.6.7.889","article-title":"Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway","volume":"6","author":"Ma","year":"1995","journal-title":"Mol Biol Cell"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB22","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/0092-8674(90)90668-5","article-title":"FUS3 encodes a cdc2+\/CDC28-related kinase required for the transition from mitosis into conjugation","volume":"60","author":"Elion","year":"1990","journal-title":"Cell"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB23","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1083\/jcb.140.3.461","article-title":"Pheromone-regulated genes required for yeast mating differentiation","volume":"140","author":"Erdman","year":"1998","journal-title":"J Cell Biol"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB24","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1101\/gad.6.7.1293","article-title":"Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein","volume":"6","author":"Stevenson","year":"1992","journal-title":"Genes Dev"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB25","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1091\/mbc.4.5.495","article-title":"FUS3 phosphorylates multiple components of the mating signal transduction cascade","volume":"4","author":"Elion","year":"1993","journal-title":"Mol Biol Cell"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB26","doi-asserted-by":"crossref","first-page":"4752","DOI":"10.1128\/JVI.71.6.4752-4760.1997","article-title":"Epstein-Barr virus latent membrane protein 2 associates with and is a substrate for mitogen-activated protein kinase","volume":"71","author":"Panousis","year":"1997","journal-title":"J Virol"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB27","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1101\/SQB.1991.056.01.007","article-title":"Functional redundancy in the yeast cell cycle","volume":"56","author":"Elion","year":"1991","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB28","doi-asserted-by":"crossref","first-page":"2830","DOI":"10.1128\/MCB.16.6.2830","article-title":"Ste12 and Mcm1 regulate cell cycle-dependent transcription of FAR1","volume":"16","author":"Oehlen","year":"1996","journal-title":"Mol Cell Biol"},{"key":"10.1016\/S0960-9822(01)00370-0_BIB29","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1126\/science.284.5411.92","article-title":"Complexity in biological signaling systems","volume":"284","author":"Weng","year":"1999","journal-title":"Science"}],"container-title":["Current Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982201003700?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982201003700?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T11:22:17Z","timestamp":1580210537000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960982201003700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,8]]},"references-count":29,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2001,8]]}},"alternative-id":["S0960982201003700"],"URL":"https:\/\/doi.org\/10.1016\/s0960-9822(01)00370-0","relation":{},"ISSN":["0960-9822"],"issn-type":[{"value":"0960-9822","type":"print"}],"subject":[],"published":{"date-parts":[[2001,8]]}}}