{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T18:29:27Z","timestamp":1770056967538,"version":"3.49.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NeuroImage"],"published-print":{"date-parts":[[2003,6]]},"DOI":"10.1016\/s1053-8119(03)00090-9","type":"journal-article","created":{"date-parts":[[2003,5,13]],"date-time":"2003-05-13T01:38:09Z","timestamp":1052789889000},"page":"341-353","source":"Crossref","is-referenced-by-count":87,"title":["Estimation of bolus dispersion effects in perfusion MRI using image-based computational fluid dynamics"],"prefix":"10.1016","volume":"19","author":[{"given":"Fernando","family":"Calamante","sequence":"first","affiliation":[]},{"given":"Peter J.","family":"Yim","sequence":"additional","affiliation":[]},{"given":"Juan R.","family":"Cebral","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S1053-8119(03)00090-9_BIB1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1090\/conm\/141\/1212585","article-title":"Flow in large blood vessels","volume":"141","author":"Berger","year":"1993","journal-title":"Contemp. Math. Fluid Dyn. Biol."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB2","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/1522-2594(200009)44:3<466::AID-MRM18>3.0.CO;2-M","article-title":"Delay and dispersion effects in dynamic susceptibility contrast MRI: simulations using singular value decomposition","volume":"44","author":"Calamante","year":"2000","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB3","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1161\/01.STR.0000014208.05597.33","article-title":"Quantification of perfusion using bolus tracking MRI in stroke. Assumptions, limitations, and potential implications for clinical use","volume":"33","author":"Calamante","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB4","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/00004647-199907000-00001","article-title":"Measuring cerebral blood flow using magnetic resonance techniques","volume":"19","author":"Calamante","year":"1999","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB5","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/nme.205","article-title":"From medical images to anatomically accurate finite element grids","volume":"51","author":"Cebral","year":"2001","journal-title":"Int. J. Num. Methods Eng."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB6","unstructured":"Cebral, J.R., L\u00f6hner, R., Burgess, J.E., 2000. Computer simulation of cerebral artery clipping: relevance to aneurysm neuro-surgery planning. Proceedings of ECCOMAS 2000, Sep. 11\u201314, Barcelona, Spain"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB7","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0021-9290(01)00018-5","article-title":"Merging of intersecting triangulations for finite element modeling","volume":"34","author":"Cebral","year":"2001","journal-title":"J. Biomech."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB8","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1117\/12.463595","article-title":"Image-based finite element modeling of hemodynamics in stenosed carotid artery","volume":"4683","author":"Cebral","year":"2002","journal-title":"Proc. SPIE Med. Imaging"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1117\/12.428135","article-title":"New methods for computational fluid dynamics modeling of carotid artery from magnetic resonance angiography","volume":"4321","author":"Cebral","year":"2001","journal-title":"Proc. SPIE Med. Imaging"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB10","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1093\/brain\/awf047","article-title":"Variability of cerebral blood volume and oxygen extraction: stages of cerebral haemodynamic impairment revisited","volume":"125","author":"Derdeyn","year":"2002","journal-title":"Brain"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB11","first-page":"19","article-title":"Mesh optimization","volume":"93","author":"Hoppe","year":"1993","journal-title":"Proc. SIGGRAPH"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB12","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/(SICI)1522-2586(199909)10:3<317::AID-JMRI14>3.0.CO;2-M","article-title":"Contrast-enhanced MR angiography of the carotid bifurcation","volume":"10","author":"Korosec","year":"1999","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB13","first-page":"H1643","article-title":"Modeling regional myocardial flows from residue functions of an intravascular indicator","volume":"271","author":"Kroll","year":"1996","journal-title":"Am. J. Physiol."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB14","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1006\/jcph.1995.1107","article-title":"Robust, vectorized search algorithms for interpolation on unstructured grids","volume":"118","author":"L\u00f6hner","year":"1995","journal-title":"J. Comp. Phys."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/jcph.1996.0115","article-title":"Regridding surface triangulations","volume":"126","author":"L\u00f6hner","year":"1996","journal-title":"J. Comp. Phys."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB16","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/BF01198734","article-title":"Progress in grid generation via the advancing front technique","volume":"12","author":"L\u00f6hner","year":"1996","journal-title":"Eng. Comput."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB17","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0168-874X(96)00038-8","article-title":"Automatic unstructured grid generators","volume":"25","author":"L\u00f6hner","year":"1997","journal-title":"Finite Elements Anal. Design"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB18","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/nme.175.abs","article-title":"A parallel advancing front grid generation scheme","volume":"51","author":"L\u00f6hner","year":"2001","journal-title":"Int. J. Num. Methods Eng."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0730-725X(99)00112-5","article-title":"Quantitative perfusion imaging in carotid artery stenosis using dynamic susceptibility contrast-enhanced magnetic resonance imaging","volume":"18","author":"Lythgoe","year":"2000","journal-title":"Magn. Reson. Imaging"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB20","series-title":"Biofluid Mechanics","author":"Mazumdar","year":"1992"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB21","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2214\/ajr.159.3.1503004","article-title":"MR measurement of blood flow in the cardiovascular system","volume":"159","author":"Mostbeck","year":"1992","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB22","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1161\/01.STR.31.6.1311","article-title":"Diffusion- and perfusion-weighted MRI. Influence of severe carotid artery stenosis on the DWI\/PWI mismatch in acute stroke","volume":"31","author":"Neumann-Haefelin","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB23","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1161\/01.STR.30.8.1591","article-title":"Diffusion- and perfusion-weighted MRI. The DWI\/PWI mismatch region in acute stroke","volume":"30","author":"Neumann-Haefelin","year":"1999","journal-title":"Stroke"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB24","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1097\/00004647-199906000-00013","article-title":"Modeling cerebral blood flow and flow heterogeneity from magnetic resonance residue data","volume":"19","author":"\u00d8stergaard","year":"1999","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB25","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1002\/mrm.1910360510","article-title":"High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I. Mathematical approach and statistical analysis","volume":"36","author":"\u00d8stergaard","year":"1996","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB26","unstructured":"Owen, S.J., 1998. A survey of unstructured mesh generation technology. Proceedings of the 7th International Meshing Roundtable, October 26\u201328, Dearborn, MI, Sandia National Lab, pp. 239\u2013267"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB27","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1161\/01.STR.32.5.1140","article-title":"Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weigted MRI and apparent diffusion coefficient","volume":"32","author":"R\u00f8hl","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB28","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1212\/WNL.53.7.1528","article-title":"The ischemic penumbra. operationally defined by diffusion and perfusion MRI","volume":"53","author":"Schlaug","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB29","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/mrm.10115","article-title":"Quantification of myocardial blood flow and blood flow reserve in the presence of arterial dispersion: a simulation study","volume":"47","author":"Schmitt","year":"2002","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB30","first-page":"235","article-title":"What is the meaning of quantitative CBF","volume":"22","author":"Sorensen","year":"2001","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB31","doi-asserted-by":"crossref","unstructured":"Soto, O., Codina, R., 2003. A numerical model to track two-fluid interfaces based on a stabilized finite element method and the level set technique. Int. J. Num. Methods Fluids (In press)","DOI":"10.1002\/fld.277"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB32","doi-asserted-by":"crossref","unstructured":"Soto, O., L\u00f6hner, R., Cebral, J.R., Codina, R., 2001. A time-accurate implicit monolithic finite element scheme for incompressible flow problems. Proceedings of ECCOMAS CFD, September 4\u20137, Swansea, UK, September","DOI":"10.2514\/6.2001-2616"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB33","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1115\/1.1449489","article-title":"On assessing the quality of particle tracking through computational fluid dynamics models","volume":"124","author":"Tambasco","year":"2002","journal-title":"J. Biomech. Eng.,"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB34","doi-asserted-by":"crossref","unstructured":"Taubin, G., 1995. A signal processing approach to fair surface design, Proceedings of SIGGRAPH 95, 351\u2013358","DOI":"10.1145\/218380.218473"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB35","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0045-7825(98)80008-X","article-title":"Finite element modeling of blood flow in arteries","volume":"158","author":"Taylor","year":"1998","journal-title":"Comput. Methods Appl. Mech. Eng."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB36","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1113\/jphysiol.1955.sp005276","article-title":"Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradientis known","volume":"127","author":"Womersley","year":"1955","journal-title":"J. Physiol."},{"key":"10.1016\/S1053-8119(03)00090-9_BIB37","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1161\/01.STR.32.4.933","article-title":"Predicting tissue outcome in acute human cerebral ischemia combined diffusion- and perfusion-weighted MR imaging","volume":"32","author":"Wu","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB38","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1161\/hs0102.101893","article-title":"Magnetic resonance perfusion-weighted imaging of acute cerebral infarction. Effect of calculation methods and underlying vasculopathy","volume":"33","author":"Yamada","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB39","unstructured":"Yim, P.J., Cebral, J.R., Ho, V.B., Marcos, H.B., Boudewijn, G., Vasbinder, C., Rowedder, A., Sortur, A., van Engelshoven, J.M.A., Soto, O., L\u00f6hner, R., Choyke, P.L., 2001a. Computational modeling of blood flow patterns from magnetic resonance imaging, Proceedings of the 87th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), November 25\u201330, Chicago, IL, p. 692"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB40","unstructured":"Yim, P.J., Cebral, J.R., L\u00f6hner, R., Ho, V.B., Choyke, P.L., 2001b. Estimation of mechanical stress on the carotid artery. Annals of Biomedical Engineering, Vol. Suppl. 1, p. S-77"},{"key":"10.1016\/S1053-8119(03)00090-9_BIB41","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1109\/42.974935","article-title":"Vessel surface reconstruction with a tubular deformable model","volume":"20","author":"Yim","year":"2002","journal-title":"IEEE Trans. Med. Imaging"}],"container-title":["NeuroImage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811903000909?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811903000909?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T07:45:48Z","timestamp":1682495148000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053811903000909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["S1053811903000909"],"URL":"https:\/\/doi.org\/10.1016\/s1053-8119(03)00090-9","relation":{},"ISSN":["1053-8119"],"issn-type":[{"value":"1053-8119","type":"print"}],"subject":[],"published":{"date-parts":[[2003,6]]}}}