{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T11:54:57Z","timestamp":1770983697702,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1995,6,1]],"date-time":"1995-06-01T00:00:00Z","timestamp":801964800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1995,6,1]],"date-time":"1995-06-01T00:00:00Z","timestamp":801964800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":6836,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[1995,6]]},"DOI":"10.1016\/s1063-4584(05)80045-7","type":"journal-article","created":{"date-parts":[[2005,10,11]],"date-time":"2005-10-11T07:23:17Z","timestamp":1129015397000},"page":"127-138","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":115,"title":["Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus"],"prefix":"10.1016","volume":"3","author":[{"given":"Simon","family":"Collier","sequence":"first","affiliation":[]},{"given":"Peter","family":"Ghosh","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S1063-4584(05)80045-7_bib1","first-page":"333","article-title":"The healing of semilunar cartilages","volume":"18","author":"King","year":"1936","journal-title":"J Bone Joint Surg [Am]"},{"key":"10.1016\/S1063-4584(05)80045-7_bib2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1177\/036354658301100305","article-title":"The microvasculature of the meniscus and its response to injury","volume":"11","author":"Arnoczky","year":"1983","journal-title":"Am J Sports Med"},{"key":"10.1016\/S1063-4584(05)80045-7_bib3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00003086-199003000-00004","article-title":"Material properties and structure-function relationships in the menisci","volume":"252","author":"Fithain","year":"1990","journal-title":"Clin Orthop"},{"key":"10.1016\/S1063-4584(05)80045-7_bib4","doi-asserted-by":"crossref","first-page":"5693","DOI":"10.1016\/S0021-9258(17)38436-3","article-title":"Cartilage-inducing factor-A\u2014apparent identity to transforming growth factor-beta","volume":"261","author":"Seyedin","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1016\/S1063-4584(05)80045-7_bib5","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1083\/jcb.105.3.1039","article-title":"Some recent advances in the chemistry and biology of transforming growth factor-\u03b2","volume":"105","author":"Sporn","year":"1987","journal-title":"Cell Biol"},{"key":"10.1016\/S1063-4584(05)80045-7_bib6","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/BF02634049","article-title":"Transforming growth factor beta: its effect on phenotype reexpression by dedifferentiated chondrocytes in the presence and absence of osteogenin","volume":"28A","author":"Harrison","year":"1992","journal-title":"In Vitro Cell Dev Biol"},{"key":"10.1016\/S1063-4584(05)80045-7_bib7","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/jcp.1041490119","article-title":"Enhanced sulfated proteoglycan core protein synthesis by incubation of rabbit chondrocytes with recombinant transforming growth factor-beta-1","volume":"149","author":"Malemud","year":"1991","journal-title":"J Cell Phys"},{"key":"10.1016\/S1063-4584(05)80045-7_bib8","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0003-9861(91)90013-9","article-title":"Transforming growth factor-beta-1 stimulates synthesis of proteoglycan aggregates in calf articular cartilage organ cultures","volume":"286","author":"Morales","year":"1991","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/S1063-4584(05)80045-7_bib9","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0003-9861(92)90368-7","article-title":"The interaction between retinoic acid and the transforming growth factors-\u03b2 in calf articular cartilage organ cultures","volume":"293","author":"Morales","year":"1992","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/S1063-4584(05)80045-7_bib10","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0003-9861(91)90212-2","article-title":"Transforming growth factor-beta in calf articular cartilage organ cultures: Synthesis and distribution","volume":"288","author":"Morales","year":"1991","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/S1063-4584(05)80045-7_bib11","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1136\/ard.51.5.643","article-title":"Inhibition of proteoglycan synthesis by transforming growth factor beta in anatomically intact articular cartilage of murine patellae","volume":"51","author":"van der Kraan","year":"1992","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/S1063-4584(05)80045-7_bib12","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/jcp.1041490115","article-title":"Interleukin-6 and transforming growth factor-\u03b2 synergistically stimulate chondrosarcoma cell proliferation","volume":"149","author":"Guerne","year":"1991","journal-title":"J Cell Physiol"},{"key":"10.1016\/S1063-4584(05)80045-7_bib13","first-page":"304","article-title":"The effects of transforming growth factor beta and serum on proteoglycan synthesis by tendon fibrocartilage","volume":"59","author":"Vogel","year":"1992","journal-title":"Eur J Cell"},{"key":"10.1016\/S1063-4584(05)80045-7_bib14","first-page":"217","article-title":"Effect of TGF-\u03b2 on canine meniscal fibrochondrocytes in cell and organ culture","volume":"15","author":"Webber","year":"1990","journal-title":"Trans Orthop Res"},{"key":"10.1016\/S1063-4584(05)80045-7_bib15","first-page":"223","article-title":"Loadbearing function of the meniscus","volume":"62","author":"Seedhom","year":"1976","journal-title":"Physiotherapy"},{"key":"10.1016\/S1063-4584(05)80045-7_bib16","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1177\/036354658201000205","article-title":"Microvasculature of the human meniscus","volume":"10","author":"Arnoczky","year":"1982","journal-title":"Am J Sports Med"},{"key":"10.1016\/S1063-4584(05)80045-7_bib17","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1159\/000212017","article-title":"Variation of collagenous and non-collagenous proteins of human knee joint menisci with age and degeneration","volume":"20","author":"Ingman","year":"1974","journal-title":"Gerontol"},{"issue":"Suppl 1","key":"10.1016\/S1063-4584(05)80045-7_bib18","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0049-0172(10)80018-6","article-title":"The effects of intra-articular administration of hyaluronan on the matrix changes induced in the lateral meniscus by total medial meniscectomy and exercise","volume":"22","author":"Hope","year":"1993","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/S1063-4584(05)80045-7_bib19","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1177\/036354658901700314","article-title":"An organ culture model for assaying wound repair of the fibrocartilaginous knee joint meniscus","volume":"17","author":"Webber","year":"1989","journal-title":"Am J Sport Med"},{"key":"10.1016\/S1063-4584(05)80045-7_bib20","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1302\/0301-620X.30B4.664","article-title":"Knee joint changes after meniscectomy","volume":"30B","author":"Fairband","year":"1948","journal-title":"J Bone Joint Surg [Am]"},{"key":"10.1016\/S1063-4584(05)80045-7_bib21","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1243\/EMED_JOUR_1985_014_028_02","article-title":"A model for the function and failure of the meniscus","volume":"14","author":"Aspden","year":"1985","journal-title":"Eng Med"},{"key":"10.1016\/S1063-4584(05)80045-7_bib22","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1136\/ard.48.5.372","article-title":"Evaluation of the effects of antiarthritic drugs on the secretion of proteoglycans by lapine chondrocytes using a novel assay procedure","volume":"48","author":"Collier","year":"1989","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/S1063-4584(05)80045-7_bib23","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3109\/03008208909043901","article-title":"Culture and growth characteristics of chondrocytes encapsulated in alginate beads","volume":"19","author":"Guo","year":"1989","journal-title":"Connect Tissue Res"},{"key":"10.1016\/S1063-4584(05)80045-7_bib24","doi-asserted-by":"crossref","first-page":"6304","DOI":"10.1016\/S0021-9258(18)88971-2","article-title":"Isolation of dermatan sulphate proteoglycans from mature bovine articular cartilage","volume":"260","author":"Rosenberg","year":"1985","journal-title":"J Biol Chem"},{"key":"10.1016\/S1063-4584(05)80045-7_bib25","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/00003086-199003000-00016","article-title":"In vitro culture of meniscal tissue","volume":"252","author":"Webber","year":"1990","journal-title":"Clin Orthop"},{"key":"10.1016\/S1063-4584(05)80045-7_bib26","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0300-9084(88)90061-2","article-title":"Cell-culture of rabbit meniscal fibrochondrocytes II. Sulfated proteoglycan synthesis","volume":"70","author":"Webber","year":"1988","journal-title":"Biochimie"},{"key":"10.1016\/S1063-4584(05)80045-7_bib27","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1042\/bj2210875","article-title":"Characterization of newly synthesised proteoglycans from rabbit menisci in organ culture","volume":"221","author":"Webber","year":"1984","journal-title":"Biochem J"},{"key":"10.1016\/S1063-4584(05)80045-7_bib28","first-page":"4416","article-title":"Use of agarose culture to measure the effect of transforming growth factor beta and epidermal growth factor on rabbit articular chondrocytes","volume":"45","author":"Skantze","year":"1985","journal-title":"Cancer Res"},{"key":"10.1016\/S1063-4584(05)80045-7_bib29","first-page":"140","article-title":"Differential effect of transforming growth factor beta on freshly isolated and cultured articular chondrocytes","volume":"19","author":"van der Kraan","year":"1992","journal-title":"J Rheumatol"},{"key":"10.1016\/S1063-4584(05)80045-7_bib30","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0014-4827(92)90186-C","article-title":"Effect of transforming growth factor beta-1 (TGF-beta-1) on matrix synthesis by monolayer cultures of rabbit articular chondrocytes during the dedifferentiation process","volume":"200","author":"Gal\u00e9ra","year":"1992","journal-title":"Exp Cell Res"},{"key":"10.1016\/S1063-4584(05)80045-7_bib31","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/jcp.1041380216","article-title":"Stimulation of cartilage-matrix proteoglycan synthesis by morphologically transformed chondrocytes grown in the presence of fibroblast growth factor and transforming growth factor-beta","volume":"138","author":"Inoue","year":"1989","journal-title":"J Cell Phys"},{"key":"10.1016\/S1063-4584(05)80045-7_bib32","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1242\/jcs.107.1.17","article-title":"Phenotypic stability of bovine articular chondrocytes after long-term culture in alginate beads","volume":"107","author":"H\u00e4uselmann","year":"1994","journal-title":"J Cell Sci"},{"key":"10.1016\/S1063-4584(05)80045-7_bib33","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/BF00210984","article-title":"Rabbit articular chondrocytes in alginate gel: Characterization of immobilized preparations and potential applications","volume":"37","author":"Tamponnet","year":"1992","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/S1063-4584(05)80045-7_bib34","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0934-8832(11)80053-3","article-title":"Synthesis and turnover of proteoglycans by human and bovine adult articular chondrocytes cultured in alginate beads","volume":"12","author":"H\u00e4uselmann","year":"1992","journal-title":"Matrix"},{"key":"10.1016\/S1063-4584(05)80045-7_bib35","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1002\/jor.1100100505","article-title":"The dermatan sulfate proteoglycans of the adult human meniscus","volume":"10","author":"Roughley","year":"1992","journal-title":"J Orthop Res"},{"key":"10.1016\/S1063-4584(05)80045-7_bib36","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0304-4165(92)90027-R","article-title":"Characterization of chondroitin\/dermatan sulfate proteoglycans synthesised by rat mammary myoepithelial and fibroblastic cell lines","volume":"1117","author":"Warburton","year":"1992","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/S1063-4584(05)80045-7_bib37","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/ki.1990.35","article-title":"Transforming growth factor-beta regulates production of proteoglycans by mesangial cells","volume":"37","author":"Border","year":"1990","journal-title":"Kidney Int"},{"key":"10.1016\/S1063-4584(05)80045-7_bib38","doi-asserted-by":"crossref","first-page":"10608","DOI":"10.1016\/S0021-9258(18)99267-7","volume":"266","author":"Kahari","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1016\/S1063-4584(05)80045-7_bib39","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1042\/bj2690551","article-title":"Non-uniform influence of transforming growth factor-beta on the biosynthesis of different forms of small chondroitin sulfate dermatan sulfate proteoglycan","volume":"269","author":"Breuer","year":"1990","journal-title":"Biochem J"},{"key":"10.1016\/S1063-4584(05)80045-7_bib40","series-title":"Articular Cartilage and Osteoarthritis","first-page":"45","article-title":"Structure and funciton of dermatan sulphate proteoglycans in articular cartilage","author":"Rosenberg","year":"1991"},{"key":"10.1016\/S1063-4584(05)80045-7_bib41","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3109\/03008209209006999","article-title":"Proteoglycans from osteoarthritic human articular cartilage influence type II collagen in vitro fibrillogenesis","volume":"27","author":"Karvonen","year":"1992","journal-title":"Connect Tiss Res"},{"key":"10.1016\/S1063-4584(05)80045-7_bib42","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00003086-199404000-00043","article-title":"Enhancement of periosteal chondrogenesis in vitro. Dose-response for transforming growth factor-beta 1 (TGF-\u03b21)","volume":"301","author":"Miura","year":"1994","journal-title":"Clin Orthop"},{"key":"10.1016\/S1063-4584(05)80045-7_bib43","first-page":"236","article-title":"Induction of repair on partial thickness articular cartilage lessions by timed release of TGF-\u03b2","volume":"40","author":"Hunziker","year":"1994","journal-title":"Trans Orthop Res"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458405800457?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458405800457?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:09:52Z","timestamp":1761016192000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458405800457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,6]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1995,6]]}},"alternative-id":["S1063458405800457"],"URL":"https:\/\/doi.org\/10.1016\/s1063-4584(05)80045-7","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[1995,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/S1063-4584(05)80045-7","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1995 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}