{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:33:59Z","timestamp":1779345239848,"version":"3.51.4"},"reference-count":40,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4276,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Immunity"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1016\/s1074-7613(01)00224-2","type":"journal-article","created":{"date-parts":[[2004,4,21]],"date-time":"2004-04-21T01:15:11Z","timestamp":1082510111000},"page":"739-750","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":193,"title":["ERM-Dependent Movement of CD43 Defines a Novel Protein Complex Distal to the Immunological Synapse"],"prefix":"10.1016","volume":"15","author":[{"given":"Eric J.","family":"Allenspach","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Cullinan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiankun","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qizhi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda G.","family":"Tesciuba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy L.","family":"Cannon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephenie M.","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renell","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janis K.","family":"Burkhardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne I.","family":"Sperling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S1074-7613(01)00224-2_BIB1","doi-asserted-by":"crossref","first-page":"985","DOI":"10.4049\/jimmunol.154.3.985","article-title":"Distinct signal transduction in mouse CD4+ and CD8+ splenic T cells after CD28 receptor ligation","volume":"154","author":"Abe","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB2","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1182\/blood.V95.7.2413","article-title":"Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells","volume":"95","author":"Alonso-Lebrero","year":"2000","journal-title":"Blood"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1242\/jcs.112.1.111","article-title":"Disruption of dynamic cell surface architecture of NIH3T3 fibroblasts by the N-terminal domains of moesin and ezrin","volume":"112","author":"Amieva","year":"1999","journal-title":"J. Cell Sci."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB4","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1242\/jcs.107.9.2509","article-title":"Ezrin has properties to self-associate at the plasma membrane","volume":"107","author":"Andreoli","year":"1994","journal-title":"J. Cell Sci."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB5","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0955-0674(99)80013-1","article-title":"Regulation of cortical structure by the ezrin-radixin-moesin protein family","volume":"11","author":"Bretscher","year":"1999","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB6","doi-asserted-by":"crossref","first-page":"3011","DOI":"10.1242\/jcs.110.24.3011","article-title":"Ezrin","volume":"110","author":"Bretscher","year":"1997","journal-title":"J. Cell Sci."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB7","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S1074-7613(01)00178-9","article-title":"WASP recruitment to the T cell-APC contact site occurs independently of Cdc42 activation","volume":"15","author":"Cannon","year":"2001","journal-title":"Immunity"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB8","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1002\/j.1460-2075.1991.tb08022.x","article-title":"The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation","volume":"10","author":"Cyster","year":"1991","journal-title":"EMBO J."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB9","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1083\/jcb.131.2.495","article-title":"Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway","volume":"131","author":"del Pozo","year":"1995","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB10","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1083\/jcb.137.2.493","article-title":"ICAMs redistributed by chemokines to cellular uropods as a mechanism for recruitment of T lymphocytes","volume":"137","author":"del Pozo","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB11","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3109\/15419069809004468","article-title":"The two poles of the lymphocyte","volume":"6","author":"del Pozo","year":"1998","journal-title":"Cell Adhes. Commun."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB12","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1074\/jbc.274.4.2315","article-title":"Normal development of mice and unimpaired cell adhesion\/cell motility\/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout","volume":"274","author":"Doi","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB13","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1126\/science.285.5425.221","article-title":"The immunological synapse","volume":"285","author":"Grakoui","year":"1999","journal-title":"Science"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB14","doi-asserted-by":"crossref","first-page":"4449","DOI":"10.1093\/emboj\/19.17.4449","article-title":"Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain","volume":"19","author":"Hamada","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB15","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1242\/jcs.112.8.1149","article-title":"Immunofluorescence detection of ezrin\/radixin\/moesin (ERM) proteins with their carboxyl-terminal threonine phosphorylated in cultured cells and tissues","volume":"112","author":"Hayashi","year":"1999","journal-title":"J. Cell Sci."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB16","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/377535a0","article-title":"Negative regulation of T-cell adhesion and activation by CD43","volume":"377","author":"Manjunath","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB17","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1083\/jcb.140.3.647","article-title":"Rho-kinase phosphorylates COOH-terminal threonines of ezrin\/radixin\/moesin (ERM) proteins and regulates their head-to-tail association","volume":"140","author":"Matsui","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB18","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/385083a0","article-title":"Selective modulation of protein kinase C-theta during T-cell activation","volume":"385","author":"Monks","year":"1997","journal-title":"Nature"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB19","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/25764","article-title":"Three-dimensional segregation of supramolecular activation clusters in T cells","volume":"395","author":"Monks","year":"1998","journal-title":"Nature"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB20","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1091\/mbc.10.8.2669","article-title":"Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides","volume":"10","author":"Nakamura","year":"1999","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB21","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1084\/jem.170.1.259","article-title":"A monoclonal antibody to sialophorin (CD43) induces homotypic adhesion and activation of human monocytes","volume":"170","author":"Nong","year":"1989","journal-title":"J. Exp. Med."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB22","doi-asserted-by":"crossref","first-page":"27564","DOI":"10.1074\/jbc.271.44.27564","article-title":"CD43-specific activation of T cells induces association of CD43 to Fyn kinase","volume":"271","author":"Pedraza-Alva","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB23","doi-asserted-by":"crossref","first-page":"7594","DOI":"10.1074\/jbc.273.13.7594","article-title":"Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence","volume":"273","author":"Pietromonaco","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB24","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1093\/emboj\/18.3.501","article-title":"Leukocyte polarization in cell migration and immune interactions","volume":"18","author":"Sanchez-Madrid","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB25","doi-asserted-by":"crossref","first-page":"4632","DOI":"10.1182\/blood.V91.12.4632","article-title":"CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts","volume":"91","author":"Serrador","year":"1998","journal-title":"Blood"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB26","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1242\/jcs.110.13.1465","article-title":"Leukosialin (CD43, sialophorin) redistribution in uropods of polarized neutrophils is induced by CD43 cross-linking by antibodies, by colchicine or by chemotactic peptides","volume":"110","author":"Seveau","year":"1997","journal-title":"J. Cell Sci."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB27","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0014-5793(98)01674-3","article-title":"Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain","volume":"443","author":"Shcherbina","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB28","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1600-065X.1996.tb00924.x","article-title":"The complexities of T-cell co-stimulation","volume":"153","author":"Sperling","year":"1996","journal-title":"Immunol. Rev."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB29","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1084\/jem.182.1.139","article-title":"CD43 is a murine T cell costimulatory receptor that functions independently of CD28","volume":"182","author":"Sperling","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB30","doi-asserted-by":"crossref","first-page":"6459","DOI":"10.4049\/jimmunol.161.12.6459","article-title":"TCR signaling induces selective exclusion of CD43 from the T cell- antigen-presenting cell contact site","volume":"161","author":"Sperling","year":"1998","journal-title":"J. Immunol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB31","doi-asserted-by":"crossref","first-page":"23371","DOI":"10.1074\/jbc.272.37.23371","article-title":"Direct interaction of the Rho GDP dissociation inhibitor with ezrin\/radixin\/moesin initiates the activation of the Rho small G protein","volume":"272","author":"Takahashi","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB32","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1083\/jcb.125.6.1371","article-title":"Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members","volume":"125","author":"Takeuchi","year":"1994","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB33","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1006\/cimm.1994.1178","article-title":"Ligation of CD4 surface antigen induces rapid tyrosine phosphorylation of the cytoskeletal protein ezrin","volume":"156","author":"Thuillier","year":"1994","journal-title":"Cell. Immunol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB34","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/intimm\/10.5.691","article-title":"Regulation of in vitro and in vivo T cell activation by CD43","volume":"10","author":"Thurman","year":"1998","journal-title":"Int. Immunol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB35","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1083\/jcb.126.2.391","article-title":"ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons","volume":"126","author":"Tsukita","year":"1994","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0167-4838(98)00103-4","article-title":"Structure-function relationships in the ezrin family and the effect of tumor-associated point mutations in neurofibromatosis 2 protein","volume":"1387","author":"Turunen","year":"1998","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB37","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1126\/science.283.5402.680","article-title":"T lymphocyte costimulation mediated by reorganization of membrane microdomains","volume":"283","author":"Viola","year":"1999","journal-title":"Science"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB38","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1006\/cimm.2000.1716","article-title":"Identification and cloning of a CD43-associated serine\/threonine kinase","volume":"205","author":"Wang","year":"2000","journal-title":"Cell. Immunol."},{"key":"10.1016\/S1074-7613(01)00224-2_BIB39","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1126\/science.282.5397.2266","article-title":"A receptor\/cytoskeletal movement triggered by costimulation during T cell activation","volume":"282","author":"Wulfing","year":"1998","journal-title":"Science"},{"key":"10.1016\/S1074-7613(01)00224-2_BIB40","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1083\/jcb.140.4.885","article-title":"Ezrin\/radixin\/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2","volume":"140","author":"Yonemura","year":"1998","journal-title":"J. Cell Biol."}],"container-title":["Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761301002242?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074761301002242?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T07:45:57Z","timestamp":1761032757000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074761301002242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S1074761301002242"],"URL":"https:\/\/doi.org\/10.1016\/s1074-7613(01)00224-2","relation":{},"ISSN":["1074-7613"],"issn-type":[{"value":"1074-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ERM-Dependent Movement of CD43 Defines a Novel Protein Complex Distal to the Immunological Synapse","name":"articletitle","label":"Article Title"},{"value":"Immunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/S1074-7613(01)00224-2","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 Cell Press. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}