{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:43:08Z","timestamp":1773103388669,"version":"3.50.1"},"reference-count":61,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4915,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Cell"],"published-print":{"date-parts":[[2000,2]]},"DOI":"10.1016\/s1097-2765(00)80430-x","type":"journal-article","created":{"date-parts":[[2004,5,4]],"date-time":"2004-05-04T12:29:33Z","timestamp":1083673773000},"page":"355-365","source":"Crossref","is-referenced-by-count":310,"title":["The ISWI Chromatin-Remodeling Protein Is Required for Gene Expression and the Maintenance of Higher Order Chromatin Structure In Vivo"],"prefix":"10.1016","volume":"5","author":[{"given":"Renate","family":"Deuring","sequence":"first","affiliation":[]},{"given":"Laura","family":"Fanti","sequence":"additional","affiliation":[]},{"given":"Jennifer A","family":"Armstrong","sequence":"additional","affiliation":[]},{"given":"Melinda","family":"Sarte","sequence":"additional","affiliation":[]},{"given":"Ophelia","family":"Papoulas","sequence":"additional","affiliation":[]},{"given":"Matthias","family":"Prestel","sequence":"additional","affiliation":[]},{"given":"Gary","family":"Daubresse","sequence":"additional","affiliation":[]},{"given":"Megan","family":"Verardo","sequence":"additional","affiliation":[]},{"given":"Sarah L","family":"Moseley","sequence":"additional","affiliation":[]},{"given":"Maria","family":"Berloco","sequence":"additional","affiliation":[]},{"given":"Toshio","family":"Tsukiyama","sequence":"additional","affiliation":[]},{"given":"Carl","family":"Wu","sequence":"additional","affiliation":[]},{"given":"Sergio","family":"Pimpinelli","sequence":"additional","affiliation":[]},{"given":"John W","family":"Tamkun","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S1097-2765(00)80430-X_BIB1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1159\/000015027","article-title":"Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI. Cytogenet","volume":"81","author":"Aihara","year":"1998","journal-title":"Cell. Genet."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB2","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1093\/emboj\/17.12.3428","article-title":"In vitro chromatin remodelling by chromatin accessibility complex (CHRAC) at the SV40 origin of DNA replication","volume":"17","author":"Alexiadis","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB3","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1146\/annurev.ge.28.120194.002423","article-title":"Dosage compensation in Drosophila","volume":"28","author":"Baker","year":"1994","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB4","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/S0959-437X(96)80073-6","article-title":"Dosage compensation and chromatin structure in Drosophila","volume":"6","author":"Bashaw","year":"1996","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB5","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/0092-8674(88)90088-8","article-title":"Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts","volume":"53","author":"Biggin","year":"1988","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB6","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1242\/dev.118.2.401","article-title":"Targeted gene expression as a means of altering cell fates and generating dominant phenotypes","volume":"118","author":"Brand","year":"1993","journal-title":"Development"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB7","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0968-0004(97)01160-2","article-title":"Chromatin remodeling machines","volume":"23","author":"Cairns","year":"1998","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB8","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1093\/genetics\/144.4.1673","article-title":"The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster","volume":"144","author":"Chou","year":"1996","journal-title":"Genetics"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB9","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S1097-2765(00)80314-7","article-title":"ISWI is an ATP-dependent nucleosome remodeling factor","volume":"3","author":"Corona","year":"1999","journal-title":"Mol. Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0092-8674(00)80740-0","article-title":"Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle\u2013 and developmentally regulated promoter","volume":"97","author":"Cosma","year":"1999","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB11","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1242\/dev.126.6.1175","article-title":"The Drosophila kismet gene is related to chromatin-remodeling factors and is required for both segmentation and segment identity","volume":"126","author":"Daubresse","year":"1999","journal-title":"Development"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB12","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/20974","article-title":"Structure and ligand of a histone acetyltransferase bromodomain","volume":"399","author":"Dhalluin","year":"1999","journal-title":"Nature"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB13","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S1097-2765(00)80186-0","article-title":"Two-step synergism between the progesterone receptor and the DNA-binding domain of nuclear factor 1 on MMTV minichromosomes","volume":"4","author":"Di Croce","year":"1999","journal-title":"Mol. Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB14","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1128\/MCB.14.4.2225","article-title":"Identification and characterization of Drosophila relatives of the yeast transcriptional activator SNF2\/SWI2","volume":"14","author":"Elfring","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB15","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/genetics\/148.1.251","article-title":"Genetic analysis of brahma","volume":"148","author":"Elfring","year":"1998","journal-title":"Genetics"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB16","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/371806a0","article-title":"The Trithorax-like gene encodes the Drosophila GAGA factor","volume":"371","author":"Farkas","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB17","doi-asserted-by":"crossref","first-page":"3206","DOI":"10.1101\/gad.12.20.3206","article-title":"Inorganic pyrophosphatase is a component of the Drosophila nucleosome remodeling factor complex","volume":"12","author":"Gdula","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB18","doi-asserted-by":"crossref","first-page":"4717","DOI":"10.1093\/emboj\/16.15.4717","article-title":"Role of histone tails in nucleosome remodeling by Drosophila NURF","volume":"16","author":"Georgel","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB19","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1101\/gad.5.10.1786","article-title":"Chromosome tangling and breakage at anaphase result from mutations in lodestar, a Drosophila gene encoding a putative nucleoside triphosphate-binding protein","volume":"5","author":"Girdham","year":"1991","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB20","doi-asserted-by":"crossref","first-page":"3121","DOI":"10.1093\/nar\/24.16.3121","article-title":"Expanding the Mot1 subfamily","volume":"24","author":"Goldman-Levi","year":"1996","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB21","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1126\/science.2035025","article-title":"Site-specific recombination between homologous chromosomes in Drosophila","volume":"252","author":"Golic","year":"1991","journal-title":"Science"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB22","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0960-9822(95)00048-0","article-title":"Chromatin. Ga-ga over GAGA factor","volume":"5","author":"Granok","year":"1995","journal-title":"Curr. Biol."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB23","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/S0092-8674(00)80796-5","article-title":"ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF","volume":"97","author":"Hamiche","year":"1999","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB24","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.1242\/dev.125.18.3741","article-title":"decapentaplegic and wingless are regulated by eyes absent and eyegone and interact to direct the pattern of retinal differentiation in the eye disc","volume":"125","author":"Hazelett","year":"1998","journal-title":"Development"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB25","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1093\/emboj\/16.8.2054","article-title":"mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila","volume":"16","author":"Hilfiker","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB26","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0092-8674(94)90174-0","article-title":"The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes","volume":"76","author":"Hinz","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB27","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0092-8674(00)80321-9","article-title":"ACF, an ISWI-containing and ATP-utilizing chromatin assembly and remodeling factor","volume":"90","author":"Ito","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB28","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1101\/gad.13.12.1529","article-title":"ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly","volume":"13","author":"Ito","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB29","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1126\/science.282.5395.1897","article-title":"dMi-2, a hunchback-interacting protein that functions in Polycomb repression","volume":"282","author":"Kehle","year":"1998","journal-title":"Science"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB30","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1101\/gad.13.18.2339","article-title":"ATP-dependent remodeling and acetylation as regulators of chromatin fluidity","volume":"13","author":"Kingston","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB31","doi-asserted-by":"crossref","first-page":"6097","DOI":"10.1128\/MCB.17.10.6097","article-title":"The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination","volume":"17","author":"Kooistra","year":"1997","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB32","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1101\/gad.13.11.1412","article-title":"Cell cycle\u2013regulated histone acetylation required for expression of the yeast HO gene","volume":"13","author":"Krebs","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB33","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S0092-8674(00)80797-7","article-title":"Nucleosome movement by CHRAC and ISWI without disruption or trans-displacement of the histone octamer","volume":"97","author":"L\u00e4ngst","year":"1999","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB34","first-page":"193","article-title":"Method of feeding ethyl methane sulfate (EMS) to Drosophila males","volume":"43","author":"Lewis","year":"1968","journal-title":"Drosophila Inf. Serv."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB35","series-title":"The Genome of Drosophila melanogaster","author":"Lindsley","year":"1992"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB36","doi-asserted-by":"crossref","first-page":"25541","DOI":"10.1074\/jbc.273.40.25541","article-title":"A human RNA polymerase II transcription termination factor is a SWI2\/SNF2 family member","volume":"273","author":"Liu","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB37","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0959-437X(98)80139-1","article-title":"Dosage compensation in flies and worms","volume":"8","author":"Lucchesi","year":"1998","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB38","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/38444","article-title":"Crystal structure of the nucleosome core particle at 2.8 \u00c5 resolution","volume":"389","author":"Luger","year":"1997","journal-title":"Nature"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB39","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1073\/pnas.95.1.132","article-title":"Drosophila NURF-55, a WD repeat protein involved in histone metabolism","volume":"95","author":"Mart\u00ednez-Balb\u00e1s","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB40","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S1097-2765(00)80015-5","article-title":"Role of nucleosome remodeling factor NURF in transcriptional activation of chromatin","volume":"1","author":"Mizuguchi","year":"1997","journal-title":"Mol. Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB41","doi-asserted-by":"crossref","first-page":"4649","DOI":"10.1093\/nar\/20.17.4649","article-title":"Cloning of human and bovine homologs of SNF2\/SWI2","volume":"20","author":"Okabe","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB42","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1128\/MCB.18.5.2455","article-title":"Chromatin remodeling mediated by Drosophila GAGA factor and ISWI activates fushi tarazu gene transcription in vitro","volume":"18","author":"Okada","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB43","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1242\/dev.125.20.3955","article-title":"The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes","volume":"125","author":"Papoulas","year":"1998","journal-title":"Development"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB44","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1093\/genetics\/129.2.443","article-title":"The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development","volume":"129","author":"Pattatucci","year":"1991","journal-title":"Genetics"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB45","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0092-8674(00)81918-2","article-title":"SWI2\/SNF2 and related proteins","volume":"88","author":"Pazin","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB46","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1002\/(SICI)1521-1878(199809)20:9<771::AID-BIES10>3.0.CO;2-V","article-title":"Chromatin remodeling","volume":"20","author":"Pollard","year":"1998","journal-title":"Bioessays"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB47","first-page":"49","article-title":"Identifying a transcription factor interaction site on RNA polymerase II","volume":"5","author":"Skantar","year":"1995","journal-title":"Gene Expr."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB48","doi-asserted-by":"crossref","first-page":"7961","DOI":"10.1128\/MCB.13.12.7961","article-title":"Isolation of cDNAs encoding the Drosophila GAGA transcription factor","volume":"13","author":"Soeller","year":"1993","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB49","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1128\/MCB.15.5.2745","article-title":"DNA-binding and chromatin localization properties of CHD1","volume":"15","author":"Stokes","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB50","doi-asserted-by":"crossref","first-page":"3120","DOI":"10.1073\/pnas.88.8.3120","article-title":"The arflike gene encodes an essential GTP-binding protein in Drosophila","volume":"88","author":"Tamkun","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB51","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0092-8674(92)90191-E","article-title":"brahma","volume":"68","author":"Tamkun","year":"1992","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB52","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/0092-8674(95)90216-3","article-title":"Purification and properties of an ATP-dependent nucleosome remodeling factor","volume":"83","author":"Tsukiyama","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB53","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/367525a0","article-title":"ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor","volume":"367","author":"Tsukiyama","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB54","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/0092-8674(95)90217-1","article-title":"ISWI, a member of the SWI2\/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor","volume":"83","author":"Tsukiyama","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB55","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1101\/gad.13.6.686","article-title":"Characterization of the imitation switch subfamily of ATP-dependent chromatin-remodeling factors in Saccharomyces cerevisiae","volume":"13","author":"Tsukiyama","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB56","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s000180050122","article-title":"Histone acetylation as an epigenetic determinant of long-term transcriptional competence","volume":"54","author":"Turner","year":"1998","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB57","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1038\/41587","article-title":"Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II","volume":"388","author":"Varga-Weisz","year":"1997","journal-title":"Nature"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB58","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0092-8674(84)90202-2","article-title":"Protein products of the bithorax complex in Drosophila","volume":"39","author":"White","year":"1984","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB59","doi-asserted-by":"crossref","first-page":"3963","DOI":"10.1093\/nar\/25.20.3963","article-title":"Dynamics of potentiation and activation","volume":"25","author":"Wilkins","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S1097-2765(00)80430-X_BIB60","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1242\/dev.117.4.1223","article-title":"Analysis of genetic mosaics in developing and adult Drosophila tissues","volume":"117","author":"Xu","year":"1993","journal-title":"Development"},{"key":"10.1016\/S1097-2765(00)80430-X_BIB61","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1146\/annurev.bi.60.070191.003353","article-title":"RNA polymerase II","volume":"60","author":"Young","year":"1991","journal-title":"Annu. Rev. Biochem."}],"container-title":["Molecular Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109727650080430X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109727650080430X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T08:40:17Z","timestamp":1623919217000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109727650080430X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,2]]}},"alternative-id":["S109727650080430X"],"URL":"https:\/\/doi.org\/10.1016\/s1097-2765(00)80430-x","relation":{},"ISSN":["1097-2765"],"issn-type":[{"value":"1097-2765","type":"print"}],"subject":[],"published":{"date-parts":[[2000,2]]}}}