{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:23:38Z","timestamp":1779344618879,"version":"3.51.4"},"reference-count":40,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2001,4,1]],"date-time":"2001-04-01T00:00:00Z","timestamp":986083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4490,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Cell"],"published-print":{"date-parts":[[2001,4]]},"DOI":"10.1016\/s1097-2765(01)00232-5","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T21:57:13Z","timestamp":1027634233000},"page":"887-898","source":"Crossref","is-referenced-by-count":158,"title":["A Block to mRNA Nuclear Export in S. cerevisiae Leads to Hyperadenylation of Transcripts that Accumulate at the Site of Transcription"],"prefix":"10.1016","volume":"7","author":[{"given":"Torben Heick","family":"Jensen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly","family":"Patricio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terri","family":"McCarthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Rosbash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S1097-2765(01)00232-5_BIB1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0960-9822(98)70130-7","article-title":"Identification of a nuclear export receptor for tRNA","volume":"8","author":"Arts","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB2","series-title":"Current Protocols in Molecular Biology","author":"Ausubel","year":"1994"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB3","doi-asserted-by":"crossref","first-page":"18912","DOI":"10.1016\/S0021-9258(17)30603-8","article-title":"Structure and regulation of the SSA4 HSP70 gene of Saccharomyces cerevisiae","volume":"265","author":"Boorstein","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB4","doi-asserted-by":"crossref","first-page":"6548","DOI":"10.1128\/MCB.18.11.6548","article-title":"Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation","volume":"18","author":"Brown","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB5","doi-asserted-by":"crossref","first-page":"2855","DOI":"10.1093\/emboj\/18.10.2855","article-title":"Inefficient processing impairs release of RNA from the site of transcription","volume":"18","author":"Custodio","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB6","doi-asserted-by":"crossref","first-page":"3513","DOI":"10.1002\/j.1460-2075.1991.tb04915.x","article-title":"Mature mRNA 3\u2032end formation stimulates RNA export from the nucleus","volume":"10","author":"Eckner","year":"1991","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB7","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1083\/jcb.99.6.2216","article-title":"Movement of a karyophilic protein through the nuclear pores of oocytes","volume":"99","author":"Feldherr","year":"1984","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB8","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1101\/gad.6.10.1914","article-title":"Defects in mRNA 3\u2032-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20","volume":"6","author":"Forrester","year":"1992","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1083\/jcb.138.1.65","article-title":"A novel class of RanGTP binding proteins","volume":"138","author":"Gorlich","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB10","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1083\/jcb.129.4.939","article-title":"A conditional allele of the novel repeat-containing yeast nucleoporin RAT7\/NUP159 causes both rapid cessation of mRNA export and reversible clustering of nuclear pore complexes","volume":"129","author":"Gorsch","year":"1995","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB11","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1128\/MCB.16.4.1534","article-title":"Role of polyadenylation in nucleocytoplasmic transport of mRNA","volume":"16","author":"Huang","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB12","doi-asserted-by":"crossref","first-page":"8361","DOI":"10.1074\/jbc.275.12.8361","article-title":"Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts","volume":"275","author":"Hurt","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB13","doi-asserted-by":"crossref","first-page":"6535","DOI":"10.1093\/emboj\/16.21.6535","article-title":"The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus","volume":"16","author":"Izaurralde","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB14","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1093\/emboj\/18.9.2593","article-title":"The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human","volume":"18","author":"Katahira","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB15","first-page":"359","article-title":"Identification of a tRNA-specific nuclear export receptor","volume":"1","author":"Kutay","year":"1998","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB16","first-page":"1071","article-title":"Spatial consequences of defective processing of specific yeast mRNAs revealed by fluorescence in situ hybridization","volume":"1","author":"Long","year":"1995","journal-title":"RNA"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB17","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1126\/science.277.5324.383","article-title":"Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA","volume":"277","author":"Long","year":"1997","journal-title":"Science"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB18","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1146\/annurev.biochem.67.1.265","article-title":"Nucleocytoplasmic transport","volume":"67","author":"Mattaj","year":"1998","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB19","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.1128\/MCB.11.6.3075","article-title":"Mutations in the yeast RNA14 and RNA 15 genes result in an abnormal mRNA decay rate; sequence analysis reveals an RNA-binding domain in the RNA15 protein","volume":"11","author":"Minvielle-Sebastia","year":"1991","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB20","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/383357a0","article-title":"An RNA-export mediator with an essential nuclear export signal","volume":"383","author":"Murphy","year":"1996","journal-title":"Nature"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB21","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/S0092-8674(00)81666-9","article-title":"Transport of proteins and RNAs in and out of the nucleus","volume":"99","author":"Nakielny","year":"1999","journal-title":"Cell"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB22","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/nbt1098-939","article-title":"Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation","volume":"16","author":"Roth","year":"1998","journal-title":"Nat Biotechnol"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB23","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1083\/jcb.148.4.635","article-title":"The yeast nuclear pore complex; composition, architecture, and transport mechanism","volume":"148","author":"Rout","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB24","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1101\/gad.11.21.2845","article-title":"Yeast heat shock mRNAs are exported through a distinct pathway defined by Rip1p","volume":"11","author":"Saavedra","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB25","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1006\/meth.1998.0705","article-title":"Assaying the polyadenylation state of mRNAs","volume":"17","author":"Salles","year":"1999","journal-title":"Methods"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB26","doi-asserted-by":"crossref","first-page":"6826","DOI":"10.1128\/MCB.18.11.6826","article-title":"Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores","volume":"18","author":"Santos-Rosa","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB27","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.1091\/mbc.9.11.3041","article-title":"tRNA nuclear export in Saccharomyces cerevisiae","volume":"9","author":"Sarkar","year":"1998","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB28","doi-asserted-by":"crossref","first-page":"4332","DOI":"10.1093\/emboj\/18.15.4332","article-title":"Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of the nuclear pore complex via a conserved interaction with CAN\/Nup159p","volume":"18","author":"Schmitt","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB29","doi-asserted-by":"crossref","first-page":"3256","DOI":"10.1093\/emboj\/16.11.3256","article-title":"Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores","volume":"16","author":"Segref","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB30","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1093\/emboj\/17.9.2663","article-title":"Dbp5p\/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export","volume":"17","author":"Snay-Hodge","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB31","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0955-0674(99)80055-6","article-title":"The nuclear pore complex","volume":"11","author":"Stoffler","year":"1999","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB32","doi-asserted-by":"crossref","first-page":"5761","DOI":"10.1093\/emboj\/18.20.5761","article-title":"The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p\/Dbp5p and a new protein Ymr255p","volume":"18","author":"Strahm","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB33","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1083\/jcb.150.4.695","article-title":"Binding of the Mex67p\/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export","volume":"150","author":"Stra\u00dfer","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB34","doi-asserted-by":"crossref","first-page":"3303","DOI":"10.1101\/gad.12.21.3303","article-title":"Nuclear RNA export","volume":"12","author":"Stutz","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB35","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1101\/gad.11.21.2857","article-title":"The yeast nucleoporin Rip1p contributes to multiple export pathways with no essential role for its FG-repeat region","volume":"11","author":"Stutz","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB36","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1093\/emboj\/17.9.2651","article-title":"Dbp5p, a cytosolic RNA helicase is required for poly (A)+ RNA export","volume":"17","author":"Tseng","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB37","doi-asserted-by":"crossref","first-page":"3996","DOI":"10.1128\/MCB.20.11.3996-4005.2000","article-title":"Nuclear export of heat shock and non-heat-shock mRNA occurs via similar pathways","volume":"20","author":"Vainberg","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB38","doi-asserted-by":"crossref","first-page":"6779","DOI":"10.1073\/pnas.95.12.6779","article-title":"The human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A)+ RNA export","volume":"95","author":"Watkins","year":"1998","journal-title":"Proc.Natl.Acad.Sci.USA"},{"key":"10.1016\/S1097-2765(01)00232-5_BIB39","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0962-8924(98)01248-3","article-title":"Karyopherins and kissing cousins","volume":"8","author":"Wozniak","year":"1998","journal-title":"Trends Cell Biol."},{"key":"10.1016\/S1097-2765(01)00232-5_BIB40","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1128\/MMBR.63.2.405-445.1999","article-title":"Formation of mRNA 3\u2032 ends in eukaryotes","volume":"63","author":"Zhao","year":"1999","journal-title":"Microbiol. Mol. Biol. Rev."}],"container-title":["Molecular Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097276501002325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097276501002325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T07:22:37Z","timestamp":1620804157000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1097276501002325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2001,4]]}},"alternative-id":["S1097276501002325"],"URL":"https:\/\/doi.org\/10.1016\/s1097-2765(01)00232-5","relation":{},"ISSN":["1097-2765"],"issn-type":[{"value":"1097-2765","type":"print"}],"subject":[],"published":{"date-parts":[[2001,4]]}}}