{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T22:27:59Z","timestamp":1776724079006,"version":"3.51.2"},"reference-count":106,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2002,6,1]],"date-time":"2002-06-01T00:00:00Z","timestamp":1022889600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2002,6,1]],"date-time":"2002-06-01T00:00:00Z","timestamp":1022889600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["9730247N"],"award-info":[{"award-number":["9730247N"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine &amp; Growth Factor Reviews"],"published-print":{"date-parts":[[2002,6]]},"DOI":"10.1016\/s1359-6101(02)00012-6","type":"journal-article","created":{"date-parts":[[2002,9,17]],"date-time":"2002-09-17T12:02:43Z","timestamp":1032264163000},"page":"223-240","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":172,"title":["The family of IL-10-related cytokines and their receptors: related, but to what extent?"],"prefix":"10.1016","volume":"13","author":[{"given":"Sergei V","family":"Kotenko","sequence":"first","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S1359-6101(02)00012-6_BIB1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0092-8674(01)00187-8","article-title":"Interleukin-20: discovery, receptor identification, and role in epidermal function","volume":"104","author":"Blumberg","year":"2001","journal-title":"Cell"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB2","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.4049\/jimmunol.164.4.1814","article-title":"Cloning and characterization of IL-10-related T-cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9","volume":"164","author":"Dumoutier","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB3","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/sj.gene.6363714","article-title":"Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)","volume":"1","author":"Gallagher","year":"2000","journal-title":"Genes Immun."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB4","first-page":"2477","article-title":"Subtraction hybridization identifies a novel melanoma differentiation associated gene, MDA-7, modulated during human melanoma differentiation, growth and progression","volume":"11","author":"Jiang","year":"1995","journal-title":"Oncogene"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB5","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1128\/JVI.74.8.3881-3887.2000","article-title":"Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri","volume":"74","author":"Knappe","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1097-4644(19990701)74:1<1::AID-JCB1>3.0.CO;2-M","article-title":"Cutaneous rat wounds express c49a, a novel gene with homology to the human melanoma differentiation associated gene, MDA-7","volume":"74","author":"Soo","year":"1999","journal-title":"J. Cell Biochem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB7","doi-asserted-by":"crossref","first-page":"24436","DOI":"10.1074\/jbc.M001958200","article-title":"Identification of a novel ligand\u2013receptor pair constitutively activated by ras oncogenes","volume":"275","author":"Zhang","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB8","doi-asserted-by":"crossref","first-page":"5859","DOI":"10.4049\/jimmunol.166.10.5859","article-title":"Cutting edge: FISP (IL-4-induced secreted protein), a novel cytokine-like molecule secreted by Th2 cells","volume":"166","author":"Schaefer","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB9","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1146\/annurev.immunol.19.1.683","article-title":"Interleukin-10 and the interleukin-10 receptor","volume":"19","author":"Moore","year":"2001","journal-title":"Annu. Rev Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB10","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/ijc.1437","article-title":"Down-regulated melanoma differentiation associated gene (MDA-7) expression in human melanomas","volume":"94","author":"Ekmekcioglu","year":"2001","journal-title":"Int. J. Cancer"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB11","doi-asserted-by":"crossref","first-page":"7051","DOI":"10.1038\/sj.onc.1204897","article-title":"Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (MDA-7) gene with cancer specific growth suppressing and apoptosis inducing properties","volume":"20","author":"Huang","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB12","doi-asserted-by":"crossref","first-page":"14400","DOI":"10.1073\/pnas.95.24.14400","article-title":"The cancer growth suppressor gene MDA-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice","volume":"95","author":"Su","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB13","doi-asserted-by":"crossref","first-page":"9160","DOI":"10.1073\/pnas.93.17.9160","article-title":"The melanoma differentiation associated gene MDA-7 suppresses cancer cell growth","volume":"93","author":"Jiang","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/0-306-46817-4_22","article-title":"MDA-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy","volume":"465","author":"Madireddi","year":"2000","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB15","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/BF03401847","article-title":"Melanoma differentiation associated gene-7 (MDA-7): a novel anti-tumor gene for cancer gene therapy","volume":"7","author":"Mhashilkar","year":"2001","journal-title":"Mol. Med."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB16","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1038\/sj.gt.3301330","article-title":"Tumor-suppressive effects by adenovirus-mediated MDA-7 gene transfer in non-small cell lung cancer cell in vitro","volume":"7","author":"Saeki","year":"2000","journal-title":"Gene Ther."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB17","doi-asserted-by":"crossref","first-page":"3545","DOI":"10.4049\/jimmunol.167.7.3545","article-title":"Cutting edge: Stat activation by IL-19, IL-20 and MDA-7 through IL-20 receptor complexes of two types","volume":"167","author":"Dumoutier","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB18","doi-asserted-by":"crossref","first-page":"7341","DOI":"10.1074\/jbc.M106043200","article-title":"Interleukin-24 (MDA-7\/MOB-5) signals through two heterodimeric receptors, IL-22R1\/IL-20R2 and IL-20R1\/IL-20R2","volume":"277","author":"Wang","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB19","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1346-8138.2001.tb00025.x","article-title":"Cutaneous wound healing: an update","volume":"28","author":"Yamaguchi","year":"2001","journal-title":"J. Dermatol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB20","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.2174\/1381612013397573","article-title":"Role of cytokines and cytokine therapy in wound healing and fibrotic diseases","volume":"7","author":"Gharaee-Kermani","year":"2001","journal-title":"Curr. Pharm. Des"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB21","doi-asserted-by":"crossref","first-page":"10144","DOI":"10.1073\/pnas.170291697","article-title":"Human interleukin-10-related T-cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor","volume":"97","author":"Dumoutier","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB22","doi-asserted-by":"crossref","first-page":"31335","DOI":"10.1074\/jbc.M005304200","article-title":"Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R","volume":"275","author":"Xie","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB23","first-page":"172","article-title":"IL-22 is a tightly-regulated IL10-like molecule that induces an acute-phase response and renal tubular basophilia","volume":"2","author":"Pittman","year":"2001","journal-title":"Genes Immun."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB24","doi-asserted-by":"crossref","first-page":"7096","DOI":"10.4049\/jimmunol.166.12.7096","article-title":"Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity","volume":"166","author":"Kotenko","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB25","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1074\/jbc.M007837200","article-title":"Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T-cell-derived inducible factor, IL-TIF) receptor complexes","volume":"276","author":"Kotenko","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB26","doi-asserted-by":"crossref","first-page":"7090","DOI":"10.4049\/jimmunol.166.12.7090","article-title":"Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T-cell-derived inducible factor\/IL-22","volume":"166","author":"Dumoutier","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB27","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1089\/107999001317205178","article-title":"Acinar cells of the pancreas are a target of interleukin-22","volume":"21","author":"Aggarwal","year":"2001","journal-title":"J. Interferon. Cytokine Res."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB28","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1006\/bbrc.2000.3734","article-title":"Expression profiling in pancreas during the acute phase of pancreatitis using cDNA microarrays","volume":"277","author":"Dusetti","year":"2000","journal-title":"Biochem Biophys. Res. Commun."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB29","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000201430","article-title":"Pancreatitis-associated protein in patients with celiac disease: serum levels and immunocytochemical localization in small intestine","volume":"58","author":"Carroccio","year":"1997","journal-title":"Digestion"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB30","first-page":"561","article-title":"The pancreatitis-associated protein (PAP). A new candidate for neonatal screening of cystic fibrosis","volume":"317","author":"Iovanna","year":"1994","journal-title":"CR Acad. Sci. III"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB31","doi-asserted-by":"crossref","first-page":"24664","DOI":"10.1016\/S0021-9258(18)54281-2","article-title":"Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis","volume":"266","author":"Iovanna","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB32","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1098\/rstb.2000.0780","article-title":"Herpesvirus saimiri","volume":"356","author":"Fickenscher","year":"2001","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB33","doi-asserted-by":"crossref","first-page":"4562","DOI":"10.4049\/jimmunol.151.9.4562","article-title":"Synthesis of T helper 2-type cytokines at the maternal\u2013fetal interface","volume":"151","author":"Lin","year":"1993","journal-title":"J. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB34","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0167-5699(93)90235-D","article-title":"Bidirectional cytokine interactions in the maternal\u2013fetal relationship: is successful pregnancy a TH2 phenomenon","volume":"14","author":"Wegmann","year":"1993","journal-title":"Immunol. Today"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB35","unstructured":"Kotenko SV, Pestka S. Viral IL-10 variants. In: Oppenheim JJ, Feldmann M, editors. Cytokine Reference. Academic Press, New York, 2001."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB36","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1126\/science.2161559","article-title":"Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI","volume":"248","author":"Moore","year":"1990","journal-title":"Science"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB37","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1126\/science.2173142","article-title":"Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1","volume":"250","author":"Hsu","year":"1990","journal-title":"Science"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB38","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1073\/pnas.97.4.1695","article-title":"Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)","volume":"97","author":"Kotenko","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB39","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1006\/viro.2000.0195","article-title":"Primate cytomegalovirus encode and express an IL-10-like protein","volume":"268","author":"Lockridge","year":"2000","journal-title":"Virology"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB40","doi-asserted-by":"crossref","first-page":"4857","DOI":"10.1128\/jvi.71.6.4857-4861.1997","article-title":"A homolog of interleukin-10 is encoded by the poxvirus orf virus","volume":"71","author":"Fleming","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB41","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1006\/viro.2000.0761","article-title":"The genome sequence of Yaba-like disease virus, a yatapoxvirus","volume":"281","author":"Lee","year":"2001","journal-title":"Virology"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB42","doi-asserted-by":"crossref","first-page":"6934","DOI":"10.1073\/pnas.87.18.6934","article-title":"Structural design and molecular evolution of a cytokine receptor superfamily","volume":"87","author":"Bazan","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB43","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/0014-5793(91)80437-8","article-title":"Structural symmetry of the extracellular domain of the cytokine\/growth hormone\/prolactin receptor family and interferon receptors revealed by hydrophobic cluster analysis","volume":"282","author":"Thoreau","year":"1991","journal-title":"FEBS Lett."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB44","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S1357-2725(97)00121-0","article-title":"Tissue factor","volume":"30","author":"Carmeliet","year":"1998","journal-title":"Int. J. Biochem. Cell. Biol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB45","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/1359-6101(96)00017-2","article-title":"The type-I interferon receptor. The long and short of it","volume":"7","author":"Domanski","year":"1996","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB46","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1089\/107999099313019","article-title":"The type I interferon receptor: structure, function, and evolution of a family business","volume":"19","author":"Mogensen","year":"1999","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB47","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0958-1669(96)80112-1","article-title":"Initiation of blood coagulation: the tissue factor\/factor VIIa complex","volume":"7","author":"Kirchhofer","year":"1996","journal-title":"Curr. Opin. Biotechnol"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB48","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S1359-6101(97)00009-9","article-title":"The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor","volume":"8","author":"Pestka","year":"1997","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB49","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1146\/annurev.immunol.15.1.563","article-title":"The IFN gamma receptor: a paradigm for cytokine receptor signaling","volume":"15","author":"Bach","year":"1997","journal-title":"Annu Rev. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB50","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1038\/sj.onc.1203524","article-title":"Jak\u2013Stat signal transduction pathway through the eyes of cytokine class II receptor complexes","volume":"19","author":"Kotenko","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB51","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1006\/scbi.2000.0311","article-title":"Role of the cytoplasmic domains of the type I interferon receptor subunits in signaling","volume":"10","author":"Prejean","year":"2000","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB52","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1006\/geno.1993.1199","article-title":"A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR","volume":"16","author":"Lutfalla","year":"1993","journal-title":"Genomics"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB53","doi-asserted-by":"crossref","first-page":"5894","DOI":"10.1093\/emboj\/16.19.5894","article-title":"Identification and functional characterization of a second chain of the interleukin-10 receptor complex","volume":"16","author":"Kotenko","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB54","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1126\/science.1902591","article-title":"Three-dimensional structure of recombinant human interferon-gamma","volume":"252","author":"Ealick","year":"1991","journal-title":"Science"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB55","doi-asserted-by":"crossref","first-page":"12118","DOI":"10.1021\/bi00038a004","article-title":"Crystal structure of interleukin-10 reveals an interferon gamma-like fold","volume":"34","author":"Walter","year":"1995","journal-title":"Biochemistry"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB56","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0969-2126(01)00193-9","article-title":"Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma","volume":"3","author":"Zdanov","year":"1995","journal-title":"Structure"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB57","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S1074-7613(01)00169-8","article-title":"Crystal structure of the IL-10\/IL-10R1 complex reveals a shared receptor binding site","volume":"15","author":"Josephson","year":"2001","journal-title":"Immunity"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB58","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/376230a0","article-title":"Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor [see comments]","volume":"376","author":"Walter","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB59","doi-asserted-by":"crossref","first-page":"3214","DOI":"10.1128\/MCB.16.6.3214","article-title":"Ligand-induced assembly and activation of the gamma interferon receptor in intacT-cells","volume":"16","author":"Bach","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB60","doi-asserted-by":"crossref","first-page":"20915","DOI":"10.1074\/jbc.270.36.20915","article-title":"Interaction between the components of the interferon gamma receptor complex","volume":"270","author":"Kotenko","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB61","doi-asserted-by":"crossref","first-page":"17174","DOI":"10.1074\/jbc.271.29.17174","article-title":"Other kinases can substitute for Jak2 in signal transduction by interferon-gamma","volume":"271","author":"Kotenko","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB62","doi-asserted-by":"crossref","first-page":"5007","DOI":"10.1073\/pnas.96.9.5007","article-title":"The intracellular domain of interferon-receptor 2c (IFN-R2c) chain is responsible for Stat activation","volume":"96","author":"Kotenko","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB63","doi-asserted-by":"crossref","first-page":"9511","DOI":"10.1073\/pnas.171303198","article-title":"A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist","volume":"98","author":"Xu","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB64","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/sj.gene.6363786","article-title":"A novel, soluble homologue of the human IL-10 receptor with preferential expression in placenta","volume":"2","author":"Gruenberg","year":"2001","journal-title":"Genes Immun."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB65","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0014-5793(96)00990-8","article-title":"IL-10 induces DNA binding activity of three Stat proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes","volume":"394","author":"Wehinger","year":"1996","journal-title":"FEBS Lett."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB66","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.4049\/jimmunol.155.3.1079","article-title":"IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of Stat1 alpha and Stat3 complexes in human T-cells and monocytes","volume":"155","author":"Finbloom","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB67","doi-asserted-by":"crossref","first-page":"27954","DOI":"10.1074\/jbc.271.44.27954","article-title":"Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain","volume":"271","author":"Weber-Nordt","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB68","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1126\/science.7871433","article-title":"Choice of Stats and other substrates specified by modular tyrosine-based motifs in cytokine receptors","volume":"267","author":"Stahl","year":"1995","journal-title":"Science"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB69","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1128\/MCB.16.5.2074","article-title":"Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction","volume":"16","author":"Yan","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB70","unstructured":"Data were obtained from the website of the National Center for Biotechnology Information (http:\/\/www.ncbi.nlm.nih.gov\/) with the use of various software tools for analyzing genome and EST databases available at the site. January 2002."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB71","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1084\/jem.187.4.571","article-title":"The orphan receptor CRF2-4 is an essential subunit of the interleukin-10 receptor","volume":"187","author":"Spencer","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB72","doi-asserted-by":"crossref","first-page":"5022","DOI":"10.4049\/jimmunol.151.9.5022","article-title":"Immortalization with herpesvirus saimiri modulates the cytokine secretion profile of established Th1 and Th2 human T-cell clones","volume":"151","author":"De Carli","year":"1993","journal-title":"J. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB73","doi-asserted-by":"crossref","first-page":"B5","DOI":"10.1038\/35037002","article-title":"The alliance of genes and environment in asthma and allergy","volume":"402","author":"Cookson","year":"1999","journal-title":"Nature"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB74","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0091-6749(99)70398-2","article-title":"Dense mapping of chromosome 12q13.12-q23.3 and linkage to asthma and atopy","volume":"104","author":"Barnes","year":"1999","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB75","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1006\/geno.1996.0518","article-title":"Linkage of asthma and total serum IgE concentration to markers on chromosome 12q: evidence from Afro\u2013Caribbean and Caucasian populations","volume":"37","author":"Barnes","year":"1996","journal-title":"Genomics"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB76","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1006\/geno.1997.5013","article-title":"Evidence for linkage of chromosome 12q15-q24.1 markers to high total serum IgE concentrations in children of the German Multicenter Allergy Study","volume":"46","author":"Nickel","year":"1997","journal-title":"Genomics"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB77","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1159\/000024095","article-title":"Candidate gene and mutational analysis in asthma and atopy","volume":"118","author":"Wilkinson","year":"1999","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB78","first-page":"1412","article-title":"Mutation screening of interferon-gamma (IFN-gamma) as a candidate gene for asthma","volume":"27","author":"Hayden","year":"1997","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB79","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1006\/geno.1995.9952","article-title":"A 6-Mb yeast artificial chromosome contig and long-range physical map encompassing the region on chromosome 12q15 frequently rearranged in a variety of benign solid tumors","volume":"29","author":"Schoenmakers","year":"1995","journal-title":"Genomics"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB80","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/gcc.2870140112","article-title":"Regional fine mapping of the multiple-aberration region involved in uterine leiomyoma, lipoma, and pleomorphic adenoma of the salivary gland to 12q15","volume":"14","author":"Wanschura","year":"1995","journal-title":"Genes Chromosomes. Cancer"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB81","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/sj.gene.6363716","article-title":"IL-TIF\/IL-22: genomic organization and mapping of the human and mouse genes","volume":"1","author":"Dumoutier","year":"2000","journal-title":"Genes Immun."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB82","doi-asserted-by":"crossref","first-page":"21606","DOI":"10.1074\/jbc.270.37.21606","article-title":"Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signaling","volume":"270","author":"Domanski","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB83","doi-asserted-by":"crossref","first-page":"5100","DOI":"10.1002\/j.1460-2075.1995.tb00192.x","article-title":"Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster","volume":"14","author":"Lutfalla","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB84","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/0092-8674(94)90154-6","article-title":"The human interferon alpha\/beta receptor: characterization and molecular cloning","volume":"77","author":"Novick","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB85","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1182\/blood.V97.2.473","article-title":"The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties","volume":"97","author":"Hardy","year":"2001","journal-title":"Blood"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB86","doi-asserted-by":"crossref","first-page":"4657","DOI":"10.1093\/emboj\/18.17.4657","article-title":"Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis","volume":"18","author":"Sano","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB87","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1007\/s004030050467","article-title":"Interleukin-10 in cutaneous disorders: implications for its pathophysiological importance and therapeutic use","volume":"291","author":"Asadullah","year":"1999","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB88","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1046\/j.0022-202x.2001.01317.x","article-title":"Effects of systemic interleukin-10 therapy on psoriatic skin lesions: histologic, immunohistologic, and molecular biology findings","volume":"116","author":"Asadullah","year":"2001","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB89","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0092-8674(00)81959-5","article-title":"Stat3 as an oncogene","volume":"98","author":"Bromberg","year":"1999","journal-title":"Cell"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB90","doi-asserted-by":"crossref","first-page":"5709","DOI":"10.1073\/pnas.85.15.5709","article-title":"Localization and DNA sequence analysis of the transforming domain (mtrII) of human cytomegalovirus","volume":"85","author":"Razzaque","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB91","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.1128\/jvi.63.6.2866-2869.1989","article-title":"The human cytomegalovirus mtrII colinear region in strain Tanaka is transformation defective","volume":"63","author":"Jahan","year":"1989","journal-title":"J. Virol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB92","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1159\/000150275","article-title":"Identification of two promoters within human cytomegalovirus morphologic transforming region II","volume":"34","author":"Inamdar","year":"1992","journal-title":"Intervirology"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB93","doi-asserted-by":"crossref","first-page":"8691","DOI":"10.1128\/jvi.70.12.8691-8700.1996","article-title":"Human cytomegalovirus mtrII oncoprotein binds to p53 and down-regulates p53-activated transcription","volume":"70","author":"Muralidhar","year":"1996","journal-title":"J. Virol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB94","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1097\/00000542-199911000-00034","article-title":"Pancreatitis-associated protein protects the lung from leukocyte-induced injury","volume":"91","author":"Heller","year":"1999","journal-title":"Anesthesiology"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB95","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1084\/jem.188.7.1307","article-title":"Expression of interleukin-9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness","volume":"188","author":"Temann","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB96","doi-asserted-by":"crossref","first-page":"S485","DOI":"10.1016\/S0091-6749(99)70165-X","article-title":"IL-9 pathway in asthma: new therapeutic targets for allergic inflammatory disorders","volume":"103","author":"Levitt","year":"1999","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB97","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1165\/ajrcmb.19.5.3457","article-title":"Interleukin-9 promotes allergen-induced eosinophilic inflammation and airway hyperresponsiveness in transgenic mice","volume":"19","author":"McLane","year":"1998","journal-title":"Am J. Respir. Cell Mol. Biol."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB98","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1073\/pnas.88.4.1172","article-title":"Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI","volume":"88","author":"Vieira","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB99","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0092-8674(88)90050-5","article-title":"Molecular cloning and expression of the human interferon-gamma receptor","volume":"55","author":"Aguet","year":"1988","journal-title":"Cell"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB100","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/0092-8674(94)90354-9","article-title":"Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor","volume":"76","author":"Soh","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB101","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0092-8674(90)90738-Z","article-title":"Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA","volume":"60","author":"Uz\u00e9","year":"1990","journal-title":"Cell"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB102","doi-asserted-by":"crossref","first-page":"5234","DOI":"10.1021\/bi00391a004","article-title":"Human tissue factor: cDNA sequence and chromosome localization of the gene","volume":"26","author":"Scarpati","year":"1987","journal-title":"Biochemistry"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB103","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0049-3848(87)90349-5","article-title":"Cloning and expression of human tissue factor cDNA","volume":"48","author":"Fisher","year":"1987","journal-title":"Thromb. Res."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB104","doi-asserted-by":"crossref","first-page":"5148","DOI":"10.1073\/pnas.84.15.5148","article-title":"Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA","volume":"84","author":"Spicer","year":"1987","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S1359-6101(02)00012-6_BIB105","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0092-8674(87)90669-6","article-title":"Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade","volume":"50","author":"Morrissey","year":"1987","journal-title":"Cell"},{"key":"10.1016\/S1359-6101(02)00012-6_BIB106","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.4049\/jimmunol.152.4.1821","article-title":"Expression cloning and characterization of a human IL-10 receptor","volume":"152","author":"Liu","year":"1994","journal-title":"J. Immunol."}],"container-title":["Cytokine &amp; Growth Factor Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1359610102000126?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1359610102000126?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T10:52:51Z","timestamp":1761216771000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1359610102000126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6]]},"references-count":106,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,6]]}},"alternative-id":["S1359610102000126"],"URL":"https:\/\/doi.org\/10.1016\/s1359-6101(02)00012-6","relation":{},"ISSN":["1359-6101"],"issn-type":[{"value":"1359-6101","type":"print"}],"subject":[],"published":{"date-parts":[[2002,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The family of IL-10-related cytokines and their receptors: related, but to what extent?","name":"articletitle","label":"Article Title"},{"value":"Cytokine & Growth Factor Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/S1359-6101(02)00012-6","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2002 Elsevier Science Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}