{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:28:37Z","timestamp":1777526917328,"version":"3.51.4"},"reference-count":137,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T00:00:00Z","timestamp":1715299200000},"content-version":"vor","delay-in-days":4544,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Small RNAs (sRNAs) are 18-30 nt non-coding regulatory elements found in diverse organisms, which were initially identified as small double-stranded RNAs in Caenorhabditis elegans. With the development of new and improved technologies, sRNAs have also been identified and characterized in plant systems. Among them, micro RNAs (miRNAs) and small interfering RNAs (siRNAs) are found to be very important riboregulators in plants. Various types of sRNAs differ in their mode of biogenesis and in their function of gene regulation. sRNAs are involved in gene regulation at both transcriptional and post-transcriptional levels. They are known to regulate growth and development of plants. Furthermore, sRNAs especially plant miRNAs have been found to be involved in various stress responses, such as oxidative, mineral nutrient deficiency, dehydration, and even mechanical stimulus. Therefore, in the present review, we focus on the current understanding of biogenesis and regulatory mechanisms of plant sRNAs and their responses to various abiotic stresses.<\/jats:p>","DOI":"10.1016\/s1672-0229(11)60022-3","type":"journal-article","created":{"date-parts":[[2012,1,31]],"date-time":"2012-01-31T06:25:01Z","timestamp":1327991101000},"page":"183-199","source":"Crossref","is-referenced-by-count":140,"title":["Plant Small RNAs: Biogenesis, Mode of Action and Their Roles in Abiotic Stresses"],"prefix":"10.1093","volume":"9","author":[{"given":"Praveen","family":"Guleria","sequence":"first","affiliation":[{"name":"Plant Metabolic Engineering , , , , Palampur, (HP), 176061 , India"},{"name":"Biotechnology Division , , , , Palampur, (HP), 176061 , India"},{"name":"CSIR-Institute of Himalayan Bioresource Technology , , , , Palampur, (HP), 176061 , India"},{"name":"CSIR , , , , Palampur, (HP), 176061 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Plant Metabolic Engineering , , , , Palampur, (HP), 176061 , India"},{"name":"Biotechnology Division , , , , Palampur, (HP), 176061 , India"},{"name":"CSIR-Institute of Himalayan Bioresource Technology , , , , Palampur, (HP), 176061 , India"},{"name":"CSIR , , , , Palampur, (HP), 176061 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyoti","family":"Bhardwaj","sequence":"additional","affiliation":[{"name":"Plant Metabolic Engineering , , , , Palampur, (HP), 176061 , India"},{"name":"Biotechnology Division , , , , Palampur, (HP), 176061 , India"},{"name":"CSIR-Institute of Himalayan Bioresource Technology , , , , Palampur, (HP), 176061 , India"},{"name":"CSIR , , , , Palampur, (HP), 176061 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudesh Kumar","family":"Yadav","sequence":"additional","affiliation":[{"name":"Plant Metabolic Engineering , , , , Palampur, (HP), 176061 , India"},{"name":"Biotechnology Division , , , , Palampur, (HP), 176061 , India"},{"name":"CSIR-Institute of Himalayan Bioresource Technology , , , , Palampur, (HP), 176061 , India"},{"name":"CSIR , , , , Palampur, (HP), 176061 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2012,1,28]]},"reference":[{"key":"2024051008280409400_bib1","first-page":"1","article-title":"Noncoding RNA transcripts","volume":"44","author":"Szymanski","year":"2003","journal-title":"J. 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Biol."},{"key":"2024051008280409400_bib64","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.1101\/gad.402806","article-title":"MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula","volume":"20","author":"Combier","year":"2006","journal-title":"Genes Dev."},{"key":"2024051008280409400_bib65","doi-asserted-by":"crossref","first-page":"1000903","DOI":"10.1371\/journal.pgen.1000903","article-title":"MicroRNA\u2013directed siRNA biogenesis in Caenorhabditis elegans","volume":"6","author":"Correa","year":"2010","journal-title":"PLoS Genet."},{"key":"2024051008280409400_bib66","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0960-9822(00)00323-7","article-title":"EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans","volume":"10","author":"Smardon","year":"2000","journal-title":"Curr. 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Bot."},{"key":"2024051008280409400_bib104","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.tplants.2007.05.001","article-title":"Small RNAs as big players in plant abiotic stress responses and nutrient deprivation","volume":"12","author":"Sunkar","year":"2007","journal-title":"Trends Plant Sci."},{"key":"2024051008280409400_bib105","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00726-005-0251-4","article-title":"Effect of sulfur availability on the integrity of amino acid biosynthesis in plants","volume":"30","author":"Nikiforova","year":"2006","journal-title":"Amino Acids"},{"key":"2024051008280409400_bib106","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1046\/j.1365-313X.1999.00416.x","article-title":"Inter-organ signaling in plants: regulation of ATP sulfurylase and sulfate transporter genes expression in roots mediated by phloem-translocated compound","volume":"18","author":"Lappartient","year":"1996","journal-title":"Plant J."},{"key":"2024051008280409400_bib107","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1046\/j.1365-313x.2000.00768.x","article-title":"The roles of three functional sulphate transporters involved in uptake and translocation of sulfate in Arabidopsis thaliana","volume":"23","author":"Takahashi","year":"2000","journal-title":"Plant J."},{"key":"2024051008280409400_bib108","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1038\/ng1478","article-title":"Evolution of microRNA genes by inverted duplication of target gene sequences in Arabidopsis thaliana","volume":"36","author":"Allen","year":"2004","journal-title":"Nat. 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Exp. Bot."},{"key":"2024051008280409400_bib117","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/j.1365-313X.2007.03363.x","article-title":"MicroRNA399 is a long-distance signal for the regulation of plant phosphate homeostasis","volume":"53","author":"Pant","year":"2008","journal-title":"Plant J."},{"key":"2024051008280409400_bib118","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s000180050041","article-title":"Dual action of the active oxygen species during plant stress responses","volume":"57","author":"Dat","year":"2000","journal-title":"Cell. Mol. Life Sci."},{"key":"2024051008280409400_bib119","doi-asserted-by":"crossref","first-page":"16369","DOI":"10.1074\/jbc.M700138200","article-title":"Regulation of copper homeostasis by micro-RNA in Arabidopsis","volume":"282","author":"Yamasaki","year":"2007","journal-title":"J. Biol. Chem."},{"key":"2024051008280409400_bib120","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1104\/pp.118.2.637","article-title":"Superoxide dismutase in Arabidopsis: an eclectic enzyme family with disparate regulation and protein localization","volume":"118","author":"Kliebenstein","year":"1998","journal-title":"Plant Physiol."},{"key":"2024051008280409400_bib121","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1105\/tpc.106.041673","article-title":"Posttranscriptional induction of two Cu\/Zn superoxide dismutase genes in Arabidopsis is mediated by downregulation of miR398 and important for oxidative stress tolerance","volume":"18","author":"Sunkar","year":"2006","journal-title":"Plant Cell"},{"key":"2024051008280409400_bib122","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.tplants.2007.07.002","article-title":"Cold stress regulation of gene expression in plants","volume":"12","author":"Chinnusamy","year":"2007","journal-title":"Trends Plant Sci."},{"key":"2024051008280409400_bib123","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1073\/pnas.94.3.1035","article-title":"Arabidopsis thaliana CBF1 encodes an AP2 domain-containing transcription activator that binds to the C repeat\/DRE, a cis-acting DNA regulatory element that stimulates transcription in response to low temperature and water deficit","volume":"94","author":"Stockinger","year":"1997","journal-title":"Proc. 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