{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:26:01Z","timestamp":1789554361474,"version":"build-2803163510"},"reference-count":96,"publisher":"Elsevier","isbn-type":[{"value":"9780128233566","type":"print"}],"license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1016\/b978-0-12-823356-6.00016-0","type":"book-chapter","created":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T10:17:22Z","timestamp":1701425842000},"page":"71-83","source":"Crossref","is-referenced-by-count":13,"title":["Pathophysiology of migraine aura"],"prefix":"10.1016","member":"78","reference":[{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0010","first-page":"247","article-title":"On a distinct form of transient hemiopsia","volume":"160","author":"Airy","year":"1870","journal-title":"Philos Trans R Soc Lond A"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0015","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1212\/WNL.0000000000007371","article-title":"Imaging of neuroinflammation in migraine with aura: a [(11)C]PBR28 PET\/MRI study","volume":"92","author":"Albrecht","year":"2019","journal-title":"Neurology"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0020","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0002-9394(60)91650-0","article-title":"The migrainous scotoma as studied in 618 persons","volume":"49","author":"Alvarez","year":"1960","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0025","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1046\/j.1468-2982.1997.1705570.x","article-title":"Regional cerebral blood flow and oxygen metabolism during migraine with and without aura","volume":"17","author":"Andersson","year":"1997","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0030","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/ng.652","article-title":"Genome-wide association study of migraine implicates a common susceptibility variant on 8q22","volume":"42","author":"Anttila","year":"2010","journal-title":"Nat Genet"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0035","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1038\/ng.2676","article-title":"Genome wide meta-analysis identifies new susceptibility loci for migraine","volume":"45","author":"Anttila","year":"2013","journal-title":"Nat Genet"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0040","first-page":"652","article-title":"Suppression of cortical spreading depression in migraine prophylaxis","volume":"59","author":"Ayata","year":"2006","journal-title":"AnnNeurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0045","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1086\/378417","article-title":"Localization of a gene for migraine without aura to chromosome 4q21","volume":"73","author":"Bjornsson","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0050","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1046\/j.1468-2982.1995.015003186.x","article-title":"Migraine with aura and migraine without aura are not different entities","volume":"15","author":"Blau","year":"1995","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0055","series-title":"Wolff's headache and other head pain","first-page":"3","article-title":"The History of Migraine from Hippocrates to Harold Wolff","author":"Boes","year":"2008"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0060","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/nm0202-136","article-title":"Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model","volume":"8","author":"Bolay","year":"2002","journal-title":"Nat Med"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0065","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s10194-019-1042-8","article-title":"Aura and Head pain: relationship and gaps in the translational models","volume":"20","author":"Bolay","year":"2019","journal-title":"J Headache Pain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0070","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1177\/0333102420906835","article-title":"Mitochondrial genome-wide association study of migraine\u2014the HUNT study","volume":"40","author":"Borte","year":"2020","journal-title":"Cephalagia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0075","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1126\/scitranslmed.3005784","article-title":"Casein kinase id mutations in familial migraine and advanced sleep phase","volume":"5","author":"Brennan","year":"2013","journal-title":"Sci Transl Med"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0080","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1177\/0333102414566860","article-title":"Altered neurochemical coupling in the occipital cortex in migraine with visual aura","volume":"35","author":"Bridge","year":"2015","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0085","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1001\/archneur.56.5.548","article-title":"Functional MRI-BOLD of visually triggered headache in patients with migraine","volume":"56","author":"Cao","year":"1999","journal-title":"Arch Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0090","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1212\/WNL.59.1.72","article-title":"Functional MRI-BOLD of brainstem structures during visually triggered migraine","volume":"59","author":"Cao","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0095","doi-asserted-by":"crossref","first-page":"967","DOI":"10.15252\/emmm.201505944","article-title":"Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2","volume":"8","author":"Capuani","year":"2016","journal-title":"EMBO Mol Med"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0100","doi-asserted-by":"crossref","first-page":"17546","DOI":"10.1073\/pnas.1309827110","article-title":"Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects","volume":"110","author":"Cestele","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0105","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/nrneurol.2013.192","article-title":"Cortical spreading depression and migraine","volume":"9","author":"Charles","year":"2013","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0110","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1111\/j.1468-2982.2009.01983.x","article-title":"Cortical spreading depression-new insights and persistent questions","volume":"29","author":"Charles","year":"2009","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0115","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1093\/brain\/awx085","article-title":"Inhibition of the P2X7-PANX1 complex suppresses spreading depolarization and neuroinflammation","volume":"140","author":"Chen","year":"2017","journal-title":"Brain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0120","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/01.nrl.0000252943.82792.38","article-title":"Migraine aura","volume":"13","author":"Cutrer","year":"2007","journal-title":"Neurologist"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0125","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/ana.410430108","article-title":"Perfusion-weighted imaging defects during spontaneous migrainous aura","volume":"43","author":"Cutrer","year":"1998","journal-title":"Ann Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0130","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1212\/01.wnl.0000291618.32247.2d","article-title":"Thickening in the somatosensory cortex of patients with migraine","volume":"69","author":"DaSilva","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0135","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s10194-020-01125-2","article-title":"Genetics of migraine aura: an update","volume":"21","author":"de Boer","year":"2020","journal-title":"J Headache Pain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0140","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1177\/0333102414566820","article-title":"Systematic re-evaluation of genes from candidate gene association studies in migraine using a large genome-wide association data set","volume":"36","author":"de Vries","year":"2016","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0145","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s11916-014-0453-0","article-title":"Our evolving understanding of migraine with aura","volume":"18","author":"DeLange","year":"2014","journal-title":"Curr Pain Headache Rep"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0150","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1177\/0333102417738251","article-title":"Migraine with brainstem aura: why not a cortical origin?","volume":"38","author":"Demarquay","year":"2018","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0155","first-page":"99","article-title":"Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1","volume":"119","author":"Eikermann-Haerter","year":"2009","journal-title":"J Clin Invest"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0160","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/ana.22281","article-title":"Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression","volume":"69","author":"Eikermann-Haerter","year":"2011","journal-title":"Ann Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0165","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1468-2982.2003.00718.x","article-title":"Clinical characteristics of 362 patients with familial migraine with aura","volume":"24","author":"Eriksen","year":"2004","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0170","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1161\/01.STR.17.5.1033","article-title":"Late-life migraine accompaniments-further experience","volume":"17","author":"Fisher","year":"1986","journal-title":"Stroke"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0175","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.ncl.2019.06.002","article-title":"Transient neurologic dysfunction in migraine","volume":"37","author":"Foroozan","year":"2019","journal-title":"Neurol Clin"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0180","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1093\/brain\/awx382","article-title":"Migraine with visual aura associated with thicker visual cortex","volume":"141","author":"Gaist","year":"2018","journal-title":"Brain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0185","doi-asserted-by":"crossref","first-page":"300","DOI":"10.2174\/13892029113149990007","article-title":"Studies on the pathophysiology and genetic basis of migraine","volume":"14","author":"Gasparini","year":"2013","journal-title":"Curr Genomics"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0190","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s12864-018-4450-2","article-title":"Genome-side DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine","volume":"19","author":"Gerring","year":"2018","journal-title":"BMC Genomics"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0195","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/head.12030","article-title":"Higher glutamate to glutamine ratios in occipital regions in women with migraine during the interictal state","volume":"53","author":"Gonzalez De La Aleja","year":"2013","journal-title":"Headache"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0200","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1526-4610.1967.hed0604158.x","article-title":"Thirty years of headache research in the laboratory of the Late Dr. Harold G. Wolff","volume":"6","author":"Goodell","year":"1967","journal-title":"Headache"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0205","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1038\/ng.3598","article-title":"Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine","volume":"48","author":"Gormley","year":"2016","journal-title":"Nat Genet"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0210","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.neuron.2018.04.014","article-title":"Common variant burden contributes to the familial aggregation of migraine in 1,589 families","volume":"98","author":"Gormley","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0215","article-title":"Anatomical alterations of the visual motion processing network in migraine with and without aura","volume":"3","author":"Granziera","year":"2006","journal-title":"PLoSMed"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0220","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1586\/14737175.8.3.327","article-title":"Relevance of cortical thickness in migraine sufferers","volume":"8","author":"Hadjikhani","year":"2008","journal-title":"Expert Rev Neurother"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0225","doi-asserted-by":"crossref","first-page":"4687","DOI":"10.1073\/pnas.071582498","article-title":"Mechanisms of migraine aura revealed by functional MRI in human visual cortex","volume":"98","author":"Hadjikhani","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0230","doi-asserted-by":"crossref","first-page":"3589","DOI":"10.1093\/brain\/awt309","article-title":"Distinctive anatomical and physiological features of migraine aura revealed by 18 years of recording","volume":"136","author":"Hansen","year":"2013","journal-title":"Brain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0235","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1093\/brain\/awr048","article-title":"Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma","volume":"134","author":"Hartings","year":"2011","journal-title":"Brain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0240","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1177\/0333102418761041","article-title":"The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: a clinical and genetic study in Finnish migraine families","volume":"38","author":"Hiekkala","year":"2018","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0245","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1093\/brain\/awx089","article-title":"Increased brainstem perfusion, but no blood-brain barrier disruption, during attacks of migraine with aura","volume":"140","author":"Hougaard","year":"2017","journal-title":"Brain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0250","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1002\/hbm.23548","article-title":"Increased intrinsic brain connectivity between pons and somatosensory cortex during attacks of migraine with aura","volume":"38","author":"Hougaard","year":"2017","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0255","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1469-7793.1999.0415m.x","article-title":"Cortical spreading depression in the gyrencephalic feline brain studied by magnetic resonance imaging","volume":"519","author":"James","year":"1999","journal-title":"JPhysiol (Lond)"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0260","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/acn3.50971","article-title":"First FHM3 mouse model shows spontaneous cortical spreading depolarizations","volume":"7","author":"Jansen","year":"2020","journal-title":"Ann Clin Transl Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0265","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/383707a0","article-title":"Notch 3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia","volume":"383","author":"Joutel","year":"1996","journal-title":"Nature"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0270","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1046\/j.1468-1331.2001.00260.x","article-title":"Familial migraine with and without aura: clinical characteristics and co-occurrence","volume":"8","author":"Kallela","year":"2001","journal-title":"Eur J Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0275","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1126\/science.1231897","article-title":"Spreading depression triggers headache by activating neuronal Panx1 channels","volume":"339","author":"Karatas","year":"2013","journal-title":"Science"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0280","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1111\/head.13101","article-title":"Aura and other neurologic dysfunction in or with migraine","volume":"57","author":"Kissoon","year":"2017","journal-title":"Headache"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0285","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1038\/nm.2216","article-title":"A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura","volume":"16","author":"Lafreni\u00e8re","year":"2010","journal-title":"Nat Med"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0290","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1001\/archneur.1966.00470160022003","article-title":"Some clinical aspects of migraine. A prospective survey of 500 patients","volume":"15","author":"Lance","year":"1966","journal-title":"Arch Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0295","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1001\/archneurpsyc.1941.02280200137007","article-title":"Patterns of cerebral integration indicated by scotomas of migraine","volume":"46","author":"Lashley","year":"1941","journal-title":"Arch Neurol Psychiatry"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0300","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1212\/WNL.53.3.537","article-title":"The prevalence and characteristics of migraine in a population-based cohort: the GEM study","volume":"53","author":"Launer","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0305","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/brain\/107.2.447","article-title":"Regional cerebral blood flow during migraine attacks by Xenon-133 inhalation and emission tomography","volume":"107","author":"Lauritzen","year":"1984","journal-title":"Brain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0310","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1152\/jn.1944.7.6.359","article-title":"Spreading depression of activity in the cerebral cortex","volume":"7","author":"Le\u00e3o","year":"1944","journal-title":"J Neurophysiol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0315","doi-asserted-by":"crossref","first-page":"1002129","DOI":"10.1371\/journal.pgen.1002129","article-title":"Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2","volume":"7","author":"Leo","year":"2011","journal-title":"PLoS Genet"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0320","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s10194-018-0877-8","article-title":"Evidence of an increase neuronal activation-to-resting glucose uptake ratio in the visual cortex of migraine patients: a study comparing 18FDG-PET and visual evoked potentials","volume":"19","author":"Lisicki","year":"2018","journal-title":"J Headache Pain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0325","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/0013-4694(58)90073-7","article-title":"Note on a possible correspondence between the scotomas of migraine and spreading depression of Le\u00e3o","volume":"10","author":"Milner","year":"1958","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0330","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1523\/JNEUROSCI.13-03-01167.1993","article-title":"Neocortical spreading depression provokes the expression of c-fos protein-like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms","volume":"13","author":"Moskowitz","year":"1993","journal-title":"J Neurosci"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0335","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/0333102417738202","article-title":"Headache classification Committee of the International Headache Society (IHS) the international classification of headache disorders, 3rd edition","volume":"38","author":"No authors listed","year":"2018","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0340","doi-asserted-by":"crossref","first-page":"3318","DOI":"10.1093\/hmg\/ddn227","article-title":"A high-density association screen of 155 ion transport genes for involvement with common migraine","volume":"17","author":"Nyholt","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0345","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/ana.410090406","article-title":"Focal hyperemia followed by spreading oligemia and impaired activation of rCBF in classic migraine","volume":"9","author":"Olesen","year":"1981","journal-title":"Ann Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0350","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s11940-012-0208-3","article-title":"Familial and sporadic hemiplegic migraine diagnosis and treatment","volume":"15","author":"Pelzer","year":"2013","journal-title":"Curr Treat Options Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0355","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1212\/WNL.0000000000004966","article-title":"Clinical spectrum of hemiplegic migraine and chances of finding a pathogenic mutation","volume":"90","author":"Pelzer","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0360","doi-asserted-by":"crossref","first-page":"3852","DOI":"10.1093\/brain\/awz342","article-title":"A causal role for TRESK loss of function in migraine mechanisms","volume":"142","author":"Pettingill","year":"2019","journal-title":"Brain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0365","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/j.bbamem.2012.11.012","article-title":"Calcium channels and migraine","volume":"1828","author":"Pietrobon","year":"2013","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0370","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.neuron.2018.11.039","article-title":"Migraine-associated TRESK mutations increase neuronal excitability through alternative translation initiation and inhibition of TREK","volume":"101","author":"Royal","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0375","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/brain\/119.2.355","article-title":"A nosographic analysis of the migraine aura in a general population","volume":"119","author":"Russell","year":"1996","journal-title":"Brain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0380","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1093\/ije\/24.3.612","article-title":"Prevalence and sex-ratio of the subtypes of migraine","volume":"24","author":"Russell","year":"1995","journal-title":"Int J Epidemiol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0385","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1046\/j.1468-2982.1996.1605305.x","article-title":"Migraine without aura and migraine with aura are inherited disorders","volume":"16","author":"Russell","year":"1996","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0390","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1046\/j.1526-4610.2002.02102.x","article-title":"Migraine without aura and migraine with aura are distinct disorders. A population-based twin survey","volume":"42","author":"Russell","year":"2002","journal-title":"Headache"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0395","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/head.13512","article-title":"Recent insights in migraine with Aura: a narrative review of advanced neuroimaging","volume":"59","author":"Russo","year":"2019","journal-title":"Headache"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0400","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1046\/j.1468-2982.1999.019008701.x","article-title":"Perfusion weighted imaging during migraine: spontaneous visual aura and headache","volume":"19","author":"Sanchez del Rio","year":"1999","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0405","first-page":"1","article-title":"The migraine tradition","volume":"49","author":"Schiller","year":"1975","journal-title":"Bull Hist Med"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0410","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.neuroscience.2013.09.002","article-title":"Cortical spreading depression induces oxidative stress in the trigeminal nociceptive system","volume":"253","author":"Shatillo","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0415","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1093\/cercor\/bhr248","article-title":"Abnormal changes of synaptic excitability in migraine with aura","volume":"22","author":"Siniatchkin","year":"2012","journal-title":"Cereb Cortex"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0420","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1152\/physrev.2001.81.3.1065","article-title":"Mechanisms of spreading depression and hypoxic spreading depression-like depolarization","volume":"81","author":"Somjen","year":"2001","journal-title":"Physiol Rev"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0425","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/ana.410410207","article-title":"Familial risk of migraine: a population-based study","volume":"41","author":"Stewart","year":"1997","journal-title":"Ann Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0430","doi-asserted-by":"crossref","first-page":"31097","DOI":"10.1074\/jbc.M802771200","article-title":"Diverse functional consequences of mutations in the Na+\/K+-ATPase alpha2-subunits causing familial hemiplegic migraine type 2","volume":"283","author":"Tavraz","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0435","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1046\/j.1468-1331.2003.00621.x","article-title":"Increased risk of migraine with typical aura in probands with familial hemiplegic migraine and their relatives","volume":"10","author":"Thomsen","year":"2003","journal-title":"Eur J Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0440","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.neuron.2009.01.027","article-title":"Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in Ca(v)2.1 knockin migraine mice","volume":"61","author":"Tottene","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0445","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1177\/0333102416657147","article-title":"Clinical features of migraine aura: results from a prospective diary-aided study","volume":"37","author":"Viana","year":"2017","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0450","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s10194-019-1008-x","article-title":"Clinical features of visual migraine aura: a systematic review","volume":"20","author":"Viana","year":"2019","journal-title":"J Headache Pain"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0455","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1111\/j.1468-2982.2007.01388.x","article-title":"Migraine aura and related phenomena: beyond scotomata and scintillations","volume":"27","author":"Vincent","year":"2007","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0460","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1086\/339078","article-title":"A susceptibility locus for migraine with aura, on chromosome 4q24","volume":"70","author":"Wessman","year":"2002","journal-title":"Am J Hum Genet"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0465","series-title":"Headache and other head pain","first-page":"648","author":"Wolff","year":"1948"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0470","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/WCO.0000000000000436","article-title":"Migraine and magnetic resonance spectroscopy: a systematic review","volume":"30","author":"Younis","year":"2017","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0475","doi-asserted-by":"crossref","first-page":"8807","DOI":"10.1523\/JNEUROSCI.0511-10.2010","article-title":"Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura","volume":"30","author":"Zhang","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0480","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1177\/0333102415591497","article-title":"Gene based pleiotropy across migraine with aura and migraine without aura patient groups","volume":"36","author":"Zhao","year":"2016","journal-title":"Cephalalgia"},{"key":"10.1016\/B978-0-12-823356-6.00016-0_bb0485","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1093\/brain\/awx130","article-title":"Cortical glutamate in migraine","volume":"140","author":"Zielman","year":"2017","journal-title":"Brain"}],"container-title":["Handbook of Clinical Neurology","Migraine Biology, Diagnosis, and Co-Morbidities"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B9780128233566000160?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B9780128233566000160?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T17:38:41Z","timestamp":1753810721000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/B9780128233566000160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"ISBN":["9780128233566"],"references-count":96,"URL":"https:\/\/doi.org\/10.1016\/b978-0-12-823356-6.00016-0","relation":{},"ISSN":["0072-9752"],"issn-type":[{"value":"0072-9752","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]}}}