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Chem."},{"key":"10.1016\/bs.acc.2017.12.001_bb0610","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.ijcard.2016.12.164","article-title":"How do macrophages sense modified low-density lipoproteins?","volume":"230","author":"Chistiakov","year":"2017","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/bs.acc.2017.12.001_bb0615","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0165576","article-title":"Carbamylated low-density lipoprotein (cLDL)-mediated induction of autophagy and its role in endothelial cell injury","volume":"11","author":"Bose","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/bs.acc.2017.12.001_bb0620","doi-asserted-by":"crossref","first-page":"H1997","DOI":"10.1152\/ajpheart.01311.2010","article-title":"Mediates endothelial cell death induced by carbamylated LDL","volume":"300","author":"Apostolov","year":"2011","journal-title":"Am. J. Physiol. Heart Circ. 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