{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:42:26Z","timestamp":1790390546843,"version":"4.1.0"},"reference-count":203,"publisher":"Elsevier","isbn-type":[{"value":"9780128151884","type":"print"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1016\/bs.ai.2018.03.001","type":"book-chapter","created":{"date-parts":[[2018,4,22]],"date-time":"2018-04-22T17:09:04Z","timestamp":1524416944000},"page":"1-34","source":"Crossref","is-referenced-by-count":53,"title":["Eosinophil Development, Disease Involvement, and Therapeutic Suppression"],"prefix":"10.1016","author":[{"given":"Patricia C.","family":"Fulkerson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc E.","family":"Rothenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0010","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/all.12776","article-title":"Phenotypic plasticity and targeting of Siglec-F(high) CD11c(low) eosinophils to the airway in a murine model of asthma","volume":"71","author":"Abdala Valencia","year":"2016","journal-title":"Allergy"},{"issue":"25","key":"10.1016\/bs.ai.2018.03.001_bb0015","doi-asserted-by":"crossref","first-page":"17406","DOI":"10.1074\/jbc.R113.546218","article-title":"Eosinophil granule proteins: Form and function","volume":"289","author":"Acharya","year":"2014","journal-title":"The Journal of Biological Chemistry"},{"issue":"3 Pt 1","key":"10.1016\/bs.ai.2018.03.001_bb0020","doi-asserted-by":"crossref","first-page":"C623","DOI":"10.1152\/ajpcell.1998.275.3.C623","article-title":"The mechanism of IL-5 signal transduction","volume":"275","author":"Adachi","year":"1998","journal-title":"The American Journal of Physiology"},{"issue":"3 Pt 1","key":"10.1016\/bs.ai.2018.03.001_bb0025","first-page":"618","article-title":"Eosinophil viability-enhancing activity in sputum from patients with bronchial asthma, contributions of interleukin-5 and granulocyte\/macrophage colony-stimulating factor","volume":"151","author":"Adachi","year":"1995","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0030","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.jaci.2008.10.022","article-title":"CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation","volume":"123","author":"Allakhverdi","year":"2009","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"7","key":"10.1016\/bs.ai.2018.03.001_bb0035","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1111\/all.12861","article-title":"IL-33 mediates reactive eosinophilopoiesis in response to airborne allergen exposure","volume":"71","author":"Anderson","year":"2016","journal-title":"Allergy"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0040","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1053\/j.gastro.2011.07.044","article-title":"An antibody against IL-5 reduces numbers of esophageal intraepithelial eosinophils in children with eosinophilic esophagitis","volume":"141","author":"Assa'ad","year":"2011","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0045","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.rdc.2010.05.003","article-title":"Clinical manifestations and treatment of Churg\u2013Strauss syndrome","volume":"36","author":"Baldini","year":"2010","journal-title":"Rheumatic Diseases Clinics of North America"},{"issue":"8","key":"10.1016\/bs.ai.2018.03.001_bb0050","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1038\/ni.f.209","article-title":"MicroRNAs: New regulators of immune cell development and function","volume":"9","author":"Baltimore","year":"2008","journal-title":"Nature Immunology"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0055","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1165\/rcmb.2003-0234OC","article-title":"Expression of interleukin-5- and granulocyte macrophage-colony-stimulating factor-responsive genes in blood and airway eosinophils","volume":"30","author":"Bates","year":"2004","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"issue":"12","key":"10.1016\/bs.ai.2018.03.001_bb0060","doi-asserted-by":"crossref","first-page":"7125","DOI":"10.4049\/jimmunol.0900634","article-title":"Human airway eosinophils respond to chemoattractants with greater eosinophil-derived neurotoxin release, adherence to fibronectin, and activation of the Ras-ERK pathway when compared with blood eosinophils","volume":"184","author":"Bates","year":"2010","journal-title":"Journal of Immunology"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0065","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1182\/blood-2008-02-139741","article-title":"Human C\/EBP-epsilon activator and repressor isoforms differentially reprogram myeloid lineage commitment and differentiation","volume":"113","author":"Bedi","year":"2009","journal-title":"Blood"},{"issue":"13","key":"10.1016\/bs.ai.2018.03.001_bb0070","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1056\/NEJMoa1403291","article-title":"Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma","volume":"371","author":"Bel","year":"2014","journal-title":"The New England Journal of Medicine"},{"issue":"8","key":"10.1016\/bs.ai.2018.03.001_bb0075","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/ni.3225","article-title":"The transcription factor XBP1 is selectively required for eosinophil differentiation","volume":"16","author":"Bettigole","year":"2015","journal-title":"Nature Immunology"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0080","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1710-1492-5-13","article-title":"Stem cells, inflammation and allergy","volume":"5","author":"Blanchet","year":"2009","journal-title":"Allergy, Asthma and Clinical Immunology"},{"issue":"10056","key":"10.1016\/bs.ai.2018.03.001_bb0085","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1016\/S0140-6736(16)31324-1","article-title":"Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting beta2-agonists (SIROCCO): A randomised, multicentre, placebo-controlled phase 3 trial","volume":"388","author":"Bleecker","year":"2016","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0090","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1365-2222.2008.03173.x","article-title":"Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors","volume":"39","author":"Bochner","year":"2009","journal-title":"Clinical and Experimental Allergy"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0095","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.4049\/jimmunol.1500510","article-title":"Transcription factor repertoire of homeostatic eosinophilopoiesis","volume":"195","author":"Bouffi","year":"2015","journal-title":"Journal of Immunology"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0100","doi-asserted-by":"crossref","first-page":"4272","DOI":"10.1182\/blood-2004-12-4883","article-title":"Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2","volume":"105","author":"Buitenhuis","year":"2005","journal-title":"Blood"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0105","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/j.jaci.2010.04.005","article-title":"Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma","volume":"125","author":"Busse","year":"2010","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0110","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1182\/blood-2003-08-2778","article-title":"Gene microarray analysis reveals interleukin-5-dependent transcriptional targets in mouse bone marrow","volume":"103","author":"Bystrom","year":"2004","journal-title":"Blood"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0115","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/j.jaci.2014.07.026","article-title":"Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome","volume":"134","author":"Caldwell","year":"2014","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"6867","key":"10.1016\/bs.ai.2018.03.001_bb0120","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/415092a","article-title":"IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA","volume":"415","author":"Calfon","year":"2002","journal-title":"Nature"},{"issue":"10","key":"10.1016\/bs.ai.2018.03.001_bb0125","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1517\/14712598.2015.1090972","article-title":"Update on reslizumab for eosinophilic asthma","volume":"15","author":"Cardet","year":"2015","journal-title":"Expert Opinion on Biological Therapy"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0130","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S2213-2600(15)00042-9","article-title":"Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: Results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials","volume":"3","author":"Castro","year":"2015","journal-title":"The Lancet Respiratory Medicine"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0135","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1182\/blood.V73.6.1504.1504","article-title":"Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, IL-6, and GMCSF","volume":"73","author":"Clutterbuck","year":"1989","journal-title":"Blood"},{"issue":"1-3","key":"10.1016\/bs.ai.2018.03.001_bb0140","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0165-2478(97)00067-9","article-title":"Granulocyte signal transduction and priming: Cause without effect?","volume":"57","author":"Coffer","year":"1997","journal-title":"Immunology Letters"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0145","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/art.37721","article-title":"Eosinophilic granulomatosis with polyangiitis (Churg\u2013Strauss): Clinical characteristics and long-term followup of the 383 patients enrolled in the French Vasculitis Study Group cohort","volume":"65","author":"Comarmond","year":"2013","journal-title":"Arthritis and Rheumatism"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0150","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1165\/ajrcmb.12.5.7742019","article-title":"Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: Effect of glucocorticoid therapy","volume":"12","author":"Corrigan","year":"1995","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0155","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.iac.2015.04.001","article-title":"Evaluation and differential diagnosis of persistent marked eosinophilia","volume":"35","author":"Curtis","year":"2015","journal-title":"Immunology and Allergy Clinics of North America"},{"key":"10.1016\/bs.ai.2018.03.001_bb0160","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2014.00570","article-title":"Eosinophil cytokines, chemokines, and growth factors: Emerging roles in immunity","volume":"5","author":"Davoine","year":"2014","journal-title":"Frontiers in Immunology"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0165","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1078\/0171-2985-00060","article-title":"Dexamethasone inhibits apoptosis of eosinophils isolated from hypereosinophilic patients","volume":"204","author":"Debierre-Grockiego","year":"2001","journal-title":"Immunobiology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0170","doi-asserted-by":"crossref","first-page":"210","DOI":"10.2350\/11-05-0130.1","article-title":"Quantity and distribution of eosinophils in the gastrointestinal tract of children","volume":"9","author":"DeBrosse","year":"2006","journal-title":"Pediatric and Developmental Pathology"},{"issue":"7","key":"10.1016\/bs.ai.2018.03.001_bb0175","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1046\/j.1365-3024.1997.d01-210.x","article-title":"Eosinophilic interleukin 5 (IL-5) transgenic mice: Eosinophil activity and impaired clearance of Schistosoma mansoni","volume":"19","author":"Dent","year":"1997","journal-title":"Parasite Immunology"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0180","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1084\/jem.172.5.1425","article-title":"Eosinophilia in transgenic mice expressing interleukin 5","volume":"172","author":"Dent","year":"1990","journal-title":"The Journal of Experimental Medicine"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0185","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1081\/JAS-120017986","article-title":"Analysis of sputum cell counts during spontaneous moderate exacerbations of asthma in comparison to the stable phase","volume":"40","author":"Di Franco","year":"2003","journal-title":"The Journal of Asthma"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0190","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1182\/blood-2013-01-473405","article-title":"Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice","volume":"122","author":"Doyle","year":"2013","journal-title":"Blood"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0195","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/ni.3412","article-title":"Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing","volume":"17","author":"Drissen","year":"2016","journal-title":"Nature Immunology"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0200","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1023\/A:1025590308147","article-title":"Glucocorticoid-induced apoptosis in human eosinophils: Mechanisms of action","volume":"8","author":"Druilhe","year":"2003","journal-title":"Apoptosis"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0205","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0092836","article-title":"Hematopoietic overexpression of FOG1 does not affect B-cells but reduces the number of circulating eosinophils","volume":"9","author":"Du Roure","year":"2014","journal-title":"PLoS One"},{"issue":"45","key":"10.1016\/bs.ai.2018.03.001_bb0210","doi-asserted-by":"crossref","first-page":"43481","DOI":"10.1074\/jbc.M204777200","article-title":"Novel combinatorial interactions of GATA-1, PU.1, and C\/EBPepsilon isoforms regulate transcription of the gene encoding eosinophil granule major basic protein","volume":"277","author":"Du","year":"2002","journal-title":"The Journal of Biological Chemistry"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0215","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1172\/JCI95693","article-title":"Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction","volume":"128","author":"Dunican","year":"2018","journal-title":"The Journal of Clinical Investigation"},{"key":"10.1016\/bs.ai.2018.03.001_bb0220","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.bcmd.2017.01.008","article-title":"The targeted eosinophil-lowering effects of dexpramipexole in clinical studies","volume":"63","author":"Dworetzky","year":"2017","journal-title":"Blood Cells, Molecules & Diseases"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0225","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s12016-015-8526-3","article-title":"The role and immunobiology of eosinophils in the respiratory system: A comprehensive review","volume":"50","author":"Eng","year":"2016","journal-title":"Clinical Reviews in Allergy and Immunology"},{"issue":"10056","key":"10.1016\/bs.ai.2018.03.001_bb0230","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1016\/S0140-6736(16)31322-8","article-title":"Benralizumab, an anti-interleukin-5 receptor alpha monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): A randomised, double-blind, placebo-controlled phase 3 trial","volume":"388","author":"FitzGerald","year":"2016","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/bs.ai.2018.03.001_bb0235","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1093\/emboj\/18.10.2812","article-title":"Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers","volume":"18","author":"Fox","year":"1999","journal-title":"The EMBO Journal"},{"key":"10.1016\/bs.ai.2018.03.001_bb0240","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3389\/fmed.2017.00115","article-title":"Transcription factors in eosinophil development and as therapeutic targets","volume":"4","author":"Fulkerson","year":"2017","journal-title":"Frontiers in Medicine"},{"issue":"44","key":"10.1016\/bs.ai.2018.03.001_bb0245","doi-asserted-by":"crossref","first-page":"16418","DOI":"10.1073\/pnas.0607863103","article-title":"A central regulatory role for eosinophils and the eotaxin\/CCR3 axis in chronic experimental allergic airway inflammation","volume":"103","author":"Fulkerson","year":"2006","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0250","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.2353\/ajpath.2006.060617","article-title":"Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling","volume":"169","author":"Fulkerson","year":"2006","journal-title":"The American Journal of Pathology"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0255","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nrd3838","article-title":"Targeting eosinophils in allergy, inflammation and beyond","volume":"12","author":"Fulkerson","year":"2013","journal-title":"Nature Reviews. Drug Discovery"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0260","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/ppul.23368","article-title":"Eosinophilic pneumonias in children: A review of the epidemiology, diagnosis, and treatment","volume":"51","author":"Giovannini-Chami","year":"2016","journal-title":"Pediatric Pulmonology"},{"issue":"24","key":"10.1016\/bs.ai.2018.03.001_bb0265","first-page":"2577","article-title":"Anti-interleukin-5 therapy and severe asthma","volume":"360","author":"Gleich","year":"2009","journal-title":"The New England Journal of Medicine"},{"issue":"8","key":"10.1016\/bs.ai.2018.03.001_bb0270","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.1182\/blood-2002-04-1039","article-title":"Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C\/EBP epsilon and PU.1","volume":"101","author":"Gombart","year":"2003","journal-title":"Blood"},{"issue":"9","key":"10.1016\/bs.ai.2018.03.001_bb0275","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1182\/blood.V97.9.2561","article-title":"Neutrophil-specific granule deficiency: Homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT\/enhancer binding protein\u2013epsilon","volume":"97","author":"Gombart","year":"2001","journal-title":"Blood"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0280","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/0091-6749(87)90207-7","article-title":"Ultrastructural and immunohistochemical evidence for release of eosinophilic granules in vivo: Cytotoxic potential in chronic eosinophilic pneumonia","volume":"79","author":"Gonzalez","year":"1987","journal-title":"The Journal of Allergy and Clinical Immunology"},{"key":"10.1016\/bs.ai.2018.03.001_bb0285","doi-asserted-by":"crossref","unstructured":"Grantham, J. G., Meadows, J. A., 3rd, & Gleich, G. J. (1986). Chronic eosinophilic pneumonia. Evidence for eosinophil degranulation and release of major basic protein. The American Journal of Medicine, 80(1), 89\u201394.","DOI":"10.1016\/0002-9343(86)90053-7"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0290","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.jaip.2013.05.009","article-title":"The management of eosinophilic esophagitis","volume":"1","author":"Greenhawt","year":"2013","journal-title":"The Journal of Allergy and Clinical Immunology. In Practice"},{"issue":"10","key":"10.1016\/bs.ai.2018.03.001_bb0295","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1056\/NEJMoa0808991","article-title":"Mepolizumab and exacerbations of refractory eosinophilic asthma","volume":"360","author":"Haldar","year":"2009","journal-title":"The New England Journal of Medicine"},{"key":"10.1016\/bs.ai.2018.03.001_bb0300","first-page":"1","article-title":"Roles of lineage-determining transcription factors in establishing open chromatin: Lessons from high-throughput studies","volume":"356","author":"Heinz","year":"2012","journal-title":"Current Topics in Microbiology and Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0305","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/nrm3949","article-title":"The selection and function of cell type-specific enhancers","volume":"16","author":"Heinz","year":"2015","journal-title":"Nature Reviews. Molecular Cell Biology"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0310","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1172\/JCI115524","article-title":"Eosinophil hematopoietins antagonize the programmed cell death of eosinophils. Cytokine and glucocorticoid effects on eosinophils maintained by endothelial cell-conditioned medium","volume":"88","author":"Her","year":"1991","journal-title":"The Journal of Clinical Investigation"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0315","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/1753465815581279","article-title":"Evidence for the efficacy and safety of anti-interleukin-5 treatment in the management of refractory eosinophilic asthma","volume":"9","author":"Hilvering","year":"2015","journal-title":"Therapeutic Advances in Respiratory Disease"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0320","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1084\/jem.20020170","article-title":"Essential and instructive roles of GATA factors in eosinophil development","volume":"195","author":"Hirasawa","year":"2002","journal-title":"The Journal of Experimental Medicine"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0325","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/mi.2015.17","article-title":"In situ hematopoiesis: A regulator of TH2 cytokine-mediated immunity and inflammation at mucosal surfaces","volume":"8","author":"Hui","year":"2015","journal-title":"Mucosal Immunology"},{"issue":"5691","key":"10.1016\/bs.ai.2018.03.001_bb0330","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1126\/science.1100283","article-title":"A critical role for eosinophils in allergic airways remodeling","volume":"305","author":"Humbles","year":"2004","journal-title":"Science"},{"issue":"21","key":"10.1016\/bs.ai.2018.03.001_bb0335","doi-asserted-by":"crossref","first-page":"3010","DOI":"10.1101\/gad.1493506","article-title":"The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages","volume":"20","author":"Iwasaki","year":"2006","journal-title":"Genes & Development"},{"issue":"12","key":"10.1016\/bs.ai.2018.03.001_bb0340","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1084\/jem.20050548","article-title":"Identification of eosinophil lineage-committed progenitors in the murine bone marrow","volume":"201","author":"Iwasaki","year":"2005","journal-title":"The Journal of Experimental Medicine"},{"issue":"19","key":"10.1016\/bs.ai.2018.03.001_bb0345","doi-asserted-by":"crossref","first-page":"3882","DOI":"10.1182\/blood-2012-06-330845","article-title":"The expanding role(s) of eosinophils in health and disease","volume":"120","author":"Jacobsen","year":"2012","journal-title":"Blood"},{"issue":"9","key":"10.1016\/bs.ai.2018.03.001_bb0350","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.4049\/jimmunol.1600611","article-title":"IL-33 precedes IL-5 in regulating eosinophil commitment and is required for eosinophil homeostasis","volume":"197","author":"Johnston","year":"2016","journal-title":"Journal of Immunology"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0355","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1038\/mi.2014.123","article-title":"IL-1beta in eosinophil-mediated small intestinal homeostasis and IgA production","volume":"8","author":"Jung","year":"2015","journal-title":"Mucosal Immunology"},{"issue":"2S","key":"10.1016\/bs.ai.2018.03.001_bb0360","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jaip.2016.11.029","article-title":"Changing paradigms in the treatment of severe asthma: The role of biologic therapies","volume":"5","author":"Katial","year":"2017","journal-title":"The Journal of Allergy and Clinical Immunology. In Practice"},{"issue":"15","key":"10.1016\/bs.ai.2018.03.001_bb0365","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1182\/blood-2016-09-687871","article-title":"The GATA factor revolution in hematology","volume":"129","author":"Katsumura","year":"2017","journal-title":"Blood"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0370","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/nri2507","article-title":"E and ID proteins branch out","volume":"9","author":"Kee","year":"2009","journal-title":"Nature Reviews. Immunology"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0375","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jaip.2017.06.006","article-title":"Hypereosinophilic syndrome subtype predicts responsiveness to glucocorticoids","volume":"6","author":"Khoury","year":"2018","journal-title":"The Journal of Allergy and Clinical Immunology. In Practice"},{"issue":"8","key":"10.1016\/bs.ai.2018.03.001_bb0380","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/nrrheum.2014.98","article-title":"Eosinophils in vasculitis: Characteristics and roles in pathogenesis","volume":"10","author":"Khoury","year":"2014","journal-title":"Nature Reviews Rheumatology"},{"issue":"10","key":"10.1016\/bs.ai.2018.03.001_bb0385","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1182\/blood-2014-02-556522","article-title":"Gfi-1 regulates the erythroid transcription factor network through Id2 repression in murine hematopoietic progenitor cells","volume":"124","author":"Kim","year":"2014","journal-title":"Blood"},{"key":"10.1016\/bs.ai.2018.03.001_bb0390","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1182\/asheducation-2015.1.92","article-title":"Eosinophilia: A pragmatic approach to diagnosis and treatment","volume":"2015","author":"Klion","year":"2015","journal-title":"Hematology. American Society of Hematology. Education Program"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0395","doi-asserted-by":"crossref","first-page":"4050","DOI":"10.1182\/blood-2003-11-3850","article-title":"Familial eosinophilia: A benign disorder?","volume":"103","author":"Klion","year":"2004","journal-title":"Blood"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0400","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1074-7613(00)80294-0","article-title":"IL-5-deficient mice have a developmental defect in CD5(+) B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses","volume":"4","author":"Kopf","year":"1996","journal-title":"Immunity"},{"issue":"12","key":"10.1016\/bs.ai.2018.03.001_bb0405","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1093\/intimm\/dxp102","article-title":"IL-5- and eosinophil-mediated inflammation: From discovery to therapy","volume":"21","author":"Kouro","year":"2009","journal-title":"International Immunology"},{"issue":"10","key":"10.1016\/bs.ai.2018.03.001_bb0410","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1101\/gad.9.10.1250","article-title":"GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts","volume":"9","author":"Kulessa","year":"1995","journal-title":"Genes & Development"},{"issue":"1-2","key":"10.1016\/bs.ai.2018.03.001_bb0415","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jns.2014.10.023","article-title":"Central nervous system involvement of hypereosinophilic syndrome: A report of 10 cases and a literature review","volume":"347","author":"Lee","year":"2014","journal-title":"Journal of the Neurological Sciences"},{"issue":"5691","key":"10.1016\/bs.ai.2018.03.001_bb0420","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1126\/science.1099472","article-title":"Defining a link with asthma in mice congenitally deficient in eosinophils","volume":"305","author":"Lee","year":"2004","journal-title":"Science"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0425","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.4049\/jimmunol.158.3.1332","article-title":"Expression of IL-5 in thymocytes\/T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies","volume":"158","author":"Lee","year":"1997","journal-title":"Journal of Immunology"},{"key":"10.1016\/bs.ai.2018.03.001_bb0430","series-title":"Eosinophils in health and disease","author":"Lee","year":"2013"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0435","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jaip.2015.01.013","article-title":"Biologic therapies targeting eosinophils: Current status and future prospects","volume":"3","author":"Legrand","year":"2015","journal-title":"The Journal of Allergy and Clinical Immunology. In Practice"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0440","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1634\/stemcells.19-2-125","article-title":"The role of C\/EBP(epsilon) in the terminal stages of granulocyte differentiation","volume":"19","author":"Lekstrom-Himes","year":"2001","journal-title":"Stem Cells"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0445","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jaci.2011.02.040","article-title":"Eosinophilic esophagitis: Updated consensus recommendations for children and adults","volume":"128","author":"Liacouras","year":"2011","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"7","key":"10.1016\/bs.ai.2018.03.001_bb0450","doi-asserted-by":"crossref","first-page":"4840","DOI":"10.4049\/jimmunol.179.7.4840","article-title":"Generation of Th1 and Th2 chemokines by human eosinophils: Evidence for a critical role of TNF-alpha","volume":"179","author":"Liu","year":"2007","journal-title":"Journal of Immunology"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0455","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1007\/s12185-012-1078-x","article-title":"Gfi-1 inhibits the expression of eosinophil major basic protein (MBP) during G-CSF-induced neutrophilic differentiation","volume":"95","author":"Liu","year":"2012","journal-title":"International Journal of Hematology"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0460","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1164\/ajrccm.161.1.9802048","article-title":"The relationship between airways inflammation and asthma severity","volume":"161","author":"Louis","year":"2000","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0465","first-page":"110","article-title":"A quantitative evaluation of mucosal eosinophils in the pediatric gastrointestinal tract","volume":"9","author":"Lowichik","year":"1996","journal-title":"Modern Pathology"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0470","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.4049\/jimmunol.1202897","article-title":"MiR-223 deficiency increases eosinophil progenitor proliferation","volume":"190","author":"Lu","year":"2013","journal-title":"Journal of Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0475","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0059397","article-title":"Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth","volume":"8","author":"Lu","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0480","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/emboj.2011.390","article-title":"FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors","volume":"31","author":"Mancini","year":"2012","journal-title":"The EMBO Journal"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0485","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1136\/heartjnl-2015-307959","article-title":"Hypereosinophilic syndrome: Cardiac diagnosis and management","volume":"102","author":"Mankad","year":"2016","journal-title":"Heart"},{"key":"10.1016\/bs.ai.2018.03.001_bb0490","article-title":"Homeostatic eosinophils: Characteristics and functions","volume":"4","author":"Marichal","year":"2017","journal-title":"Frontiers in Medicine (Lausanne)"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0495","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.immuni.2016.03.003","article-title":"Cystatin F ensures eosinophil survival by regulating granule biogenesis","volume":"44","author":"Matthews","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/bs.ai.2018.03.001_bb0500","article-title":"The biology of eosinophils and their role in asthma","volume":"4","author":"McBrien","year":"2017","journal-title":"Frontiers in Medicine (Lausanne)"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0505","doi-asserted-by":"crossref","first-page":"f43","DOI":"10.1084\/jem.20020636","article-title":"Making eosinophils through subtle shifts in transcription factor expression","volume":"195","author":"McNagny","year":"2002","journal-title":"Journal of Experimental Medicine"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0510","doi-asserted-by":"crossref","first-page":"4422","DOI":"10.4049\/jimmunol.156.11.4422","article-title":"Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes","volume":"156","author":"Meagher","year":"1996","journal-title":"Journal of Immunology"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0515","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1067\/mai.2003.1382","article-title":"Anti-IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics","volume":"111","author":"Menzies-Gow","year":"2003","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"9","key":"10.1016\/bs.ai.2018.03.001_bb0520","doi-asserted-by":"crossref","first-page":"3279","DOI":"10.1172\/JCI85664","article-title":"Lung-resident eosinophils represent a distinct regulatory eosinophil subset","volume":"126","author":"Mesnil","year":"2016","journal-title":"The Journal of Clinical Investigation"},{"issue":"7","key":"10.1016\/bs.ai.2018.03.001_bb0525","doi-asserted-by":"crossref","first-page":"5045","DOI":"10.4049\/jimmunol.181.7.5045","article-title":"IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development","volume":"181","author":"Milanovic","year":"2008","journal-title":"Journal of Immunology"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0530","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jaci.2003.10.041","article-title":"Distinguishing severe asthma phenotypes: Role of age at onset and eosinophilic inflammation","volume":"113","author":"Miranda","year":"2004","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0535","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/j.1365-2222.2011.03854.x","article-title":"Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor","volume":"42","author":"Molfino","year":"2012","journal-title":"Clinical and Experimental Allergy"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0540","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1084\/jem.20081756","article-title":"Identification of the human eosinophil lineage-committed progenitor: Revision of phenotypic definition of the human common myeloid progenitor","volume":"206","author":"Mori","year":"2009","journal-title":"The Journal of Experimental Medicine"},{"issue":"9","key":"10.1016\/bs.ai.2018.03.001_bb0545","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1111\/j.1398-9995.2012.02868.x","article-title":"Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps","volume":"67","author":"Morshed","year":"2012","journal-title":"Allergy"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0550","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1136\/jcp.2005.031922","article-title":"Eosinophil infiltration and degranulation in oesophageal mucosa from adult patients with eosinophilic oesophagitis: A retrospective and comparative study on pathological biopsy","volume":"59","author":"Mueller","year":"2006","journal-title":"Journal of Clinical Pathology"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0555","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.jaci.2017.07.048","article-title":"Eosinophils release extracellular DNA traps in response to Aspergillus fumigatus","volume":"141","author":"Muniz","year":"2018","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"10","key":"10.1016\/bs.ai.2018.03.001_bb0560","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1056\/NEJMoa0805435","article-title":"Mepolizumab for prednisone-dependent asthma with sputum eosinophilia","volume":"360","author":"Nair","year":"2009","journal-title":"The New England Journal of Medicine"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0565","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1378\/chest.103.1.162","article-title":"Chronic eosinophilic pneumonia. A long-term follow-up of 12 patients","volume":"103","author":"Naughton","year":"1993","journal-title":"Chest"},{"issue":"15","key":"10.1016\/bs.ai.2018.03.001_bb0570","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1101\/gad.12.15.2413","article-title":"Distinct C\/EBP functions are required for eosinophil lineage commitment and maturation","volume":"12","author":"Nerlov","year":"1998","journal-title":"Genes & Development"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0575","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.jaci.2009.11.029","article-title":"Cysteinyl leukotrienes acting via granule membrane-expressed receptors elicit secretion from within cell-free human eosinophil granules","volume":"125","author":"Neves","year":"2010","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0580","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.coi.2009.07.011","article-title":"Functional extracellular eosinophil granules: Novel implications in eosinophil immunobiology","volume":"21","author":"Neves","year":"2009","journal-title":"Current Opinion in Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0585","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/1074-7613(95)90046-2","article-title":"Mice deficient for the IL-3\/GM-CSF\/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal","volume":"2","author":"Nishinakamura","year":"1995","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0590","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/j.jaci.2009.09.022","article-title":"Hypereosinophilic syndrome: A multicenter, retrospective analysis of clinical characteristics and response to therapy","volume":"124","author":"Ogbogu","year":"2009","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0595","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.iac.2007.07.001","article-title":"Cardiovascular manifestations of hypereosinophilic syndromes","volume":"27","author":"Ogbogu","year":"2007","journal-title":"Immunology and Allergy Clinics of North America"},{"issue":"7622","key":"10.1016\/bs.ai.2018.03.001_bb0600","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/nature19348","article-title":"Single-cell analysis of mixed-lineage states leading to a binary cell fate choice","volume":"537","author":"Olsson","year":"2016","journal-title":"Nature"},{"issue":"13","key":"10.1016\/bs.ai.2018.03.001_bb0605","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1056\/NEJMoa1403290","article-title":"Mepolizumab treatment in patients with severe eosinophilic asthma","volume":"371","author":"Ortega","year":"2014","journal-title":"The New England Journal of Medicine"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0610","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1053\/j.gastro.2017.06.065","article-title":"Pathophysiology of eosinophilic esophagitis","volume":"154","author":"O'Shea","year":"2018","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0615","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.jaci.2017.09.022","article-title":"Eosinophils and eosinophil-associated diseases: An update","volume":"141","author":"O'Sullivan","year":"2018","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0620","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1016\/j.jaci.2013.02.042","article-title":"Anti-IL-5 therapy reduces mast cell and IL-9 cell numbers in pediatric patients with eosinophilic esophagitis","volume":"131","author":"Otani","year":"2013","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0625","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1073\/pnas.0307612100","article-title":"Coregulator-dependent facilitation of chromatin occupancy by GATA-1","volume":"101","author":"Pal","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0630","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1136\/thx.2009.122697","article-title":"Mepolizumab in refractory eosinophilic asthma","volume":"65","author":"Pavord","year":"2010","journal-title":"Thorax"},{"issue":"9842","key":"10.1016\/bs.ai.2018.03.001_bb0635","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0140-6736(12)60988-X","article-title":"Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial","volume":"380","author":"Pavord","year":"2012","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0640","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s10495-016-1226-5","article-title":"Eosinophil resistance to glucocorticoid-induced apoptosis is mediated by the transcription factor NFIL3","volume":"21","author":"Pazdrak","year":"2016","journal-title":"Apoptosis"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0645","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1189\/jlb.3A0416-166R","article-title":"SiglecF+Gr1hi eosinophils are a distinct subpopulation within the lungs of allergen-challenged mice","volume":"101","author":"Percopo","year":"2017","journal-title":"Journal of Leukocyte Biology"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0650","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1016\/j.jaci.2013.09.036","article-title":"Lysis of primed eosinophils in severe asthma","volume":"132","author":"Persson","year":"2013","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0655","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1136\/thx.52.6.569","article-title":"\u201cUltimate activation\u201d of eosinophils in vivo: Lysis and release of clusters of free eosinophil granules (Cfegs)","volume":"52","author":"Persson","year":"1997","journal-title":"Thorax"},{"issue":"12","key":"10.1016\/bs.ai.2018.03.001_bb0660","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1038\/nri3341-c1","article-title":"Primary lysis of eosinophils as a major mode of activation of eosinophils in human diseased tissues","volume":"13","author":"Persson","year":"2013","journal-title":"Nature Reviews. Immunology"},{"issue":"9","key":"10.1016\/bs.ai.2018.03.001_bb0665","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1164\/rccm.2112056","article-title":"Idiopathic acute eosinophilic pneumonia: A study of 22 patients","volume":"166","author":"Philit","year":"2002","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"10.1016\/bs.ai.2018.03.001_bb0670","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1242\/jcs.111.6.815","article-title":"Ectopic interleukin-5 receptor expression promotes proliferation without development in a multipotent hematopoietic cell line","volume":"111","author":"Pierce","year":"1998","journal-title":"Journal of Cell Science"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0675","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1182\/blood-2002-05-1488","article-title":"Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor","volume":"101","author":"Piliponsky","year":"2003","journal-title":"Blood"},{"issue":"24","key":"10.1016\/bs.ai.2018.03.001_bb0680","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1056\/NEJMoa031261","article-title":"Use of an anti-interleukin-5 antibody in the hypereosinophilic syndrome with eosinophilic dermatitis","volume":"349","author":"Plotz","year":"2003","journal-title":"The New England Journal of Medicine"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0685","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.leukres.2012.12.016","article-title":"Mortality in hypereosinophilic syndrome: 19 years of experience at Mayo Clinic with a review of the literature","volume":"37","author":"Podjasek","year":"2013","journal-title":"Leukemia Research"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0690","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1080\/02770900903015654","article-title":"Inflammatory subtypes in asthma are related to airway hyperresponsiveness to mannitol and exhaled NO","volume":"46","author":"Porsbjerg","year":"2009","journal-title":"The Journal of Asthma"},{"issue":"19","key":"10.1016\/bs.ai.2018.03.001_bb0695","doi-asserted-by":"crossref","first-page":"13099","DOI":"10.1074\/jbc.M807307200","article-title":"GATA transcription factors regulate the expression of the human eosinophil-derived neurotoxin (RNase 2) gene","volume":"284","author":"Qiu","year":"2009","journal-title":"The Journal of Biological Chemistry"},{"issue":"19","key":"10.1016\/bs.ai.2018.03.001_bb0700","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1101\/gad.177200","article-title":"Antagonism between C\/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors","volume":"14","author":"Querfurth","year":"2000","journal-title":"Genes & Development"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0705","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.dld.2014.11.009","article-title":"Clinical characteristics, treatment outcomes, and resource utilization in children and adults with eosinophilic gastroenteritis","volume":"47","author":"Reed","year":"2015","journal-title":"Digestive and Liver Disease"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0710","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1517\/14712598.2015.1041911","article-title":"Mepolizumab for eosinophilic severe asthma: Recent studies","volume":"15","author":"Robinson","year":"2015","journal-title":"Expert Opinion on Biological Therapy"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0715","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1182\/blood.V82.1.268.bloodjournal821268","article-title":"Neutrophil-specific granule deficiency includes eosinophils","volume":"82","author":"Rosenberg","year":"1993","journal-title":"Blood"},{"issue":"12","key":"10.1016\/bs.ai.2018.03.001_bb0720","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1056\/NEJMoa070812","article-title":"Treatment of patients with the hypereosinophilic syndrome with mepolizumab","volume":"358","author":"Rothenberg","year":"2008","journal-title":"The New England Journal of Medicine"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0725","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1172\/JCI113547","article-title":"Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3","volume":"81","author":"Rothenberg","year":"1988","journal-title":"The Journal of Clinical Investigation"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0730","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.jaci.2012.07.055","article-title":"Long-term safety of mepolizumab for the treatment of hypereosinophilic syndromes","volume":"131","author":"Roufosse","year":"2013","journal-title":"The Journal of Allergy Clinical Immunology"},{"key":"10.1016\/bs.ai.2018.03.001_bb0735","doi-asserted-by":"crossref","unstructured":"Roufosse, F., de Lavareille, A., Schandene, L., Cogan, E., Georgelas, A., Wagner, L., ... Klion, A. (2010). Mepolizumab as a corticosteroid-sparing agent in lymphocytic variant hypereosinophilic syndrome. The Journal of Allergy and Clinical Immunology, 126(4), 828\u2013835, e823. https:\/\/doi.org\/10.1016\/j.jaci.2010.06.049.","DOI":"10.1016\/j.jaci.2010.06.049"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0740","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1016\/j.jaci.2013.11.024","article-title":"Electron microscopy elucidates eosinophil degranulation patterns in patients with eosinophilic esophagitis","volume":"133","author":"Saffari","year":"2014","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0745","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.chest.2017.01.021","article-title":"Hematopoietic processes in eosinophilic asthma","volume":"152","author":"Salter","year":"2017","journal-title":"Chest"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0750","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1165\/rcmb.2016-0262OC","article-title":"Human bronchial epithelial cell-derived factors from severe asthmatic subjects stimulate eosinophil differentiation","volume":"58","author":"Salter","year":"2018","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"issue":"7442","key":"10.1016\/bs.ai.2018.03.001_bb0755","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/nature11930","article-title":"Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages","volume":"495","author":"Satoh","year":"2013","journal-title":"Nature"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0760","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.4049\/jimmunol.169.2.1021","article-title":"Eosinophils express functional IL-13 in eosinophilic inflammatory diseases","volume":"169","author":"Schmid-Grendelmeier","year":"2002","journal-title":"Journal of Immunology"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0765","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.immuni.2005.09.015","article-title":"IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines","volume":"23","author":"Schmitz","year":"2005","journal-title":"Immunity"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0770","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1055\/s-2006-939515","article-title":"Eosinophilic airway disorders","volume":"27","author":"Scott","year":"2006","journal-title":"Seminars in Respiratory and Critical Care Medicine"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0775","doi-asserted-by":"crossref","first-page":"3710","DOI":"10.4049\/jimmunol.149.11.3710","article-title":"Comparison of airway and blood eosinophil function after in vivo antigen challenge","volume":"149","author":"Sedgwick","year":"1992","journal-title":"Journal of Immunology"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0780","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/cea.12695","article-title":"Role of local eosinophilopoietic processes in the development of airway eosinophilia in prednisone-dependent severe asthma","volume":"46","author":"Sehmi","year":"2016","journal-title":"Clinical and Experimental Allergy"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0785","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1182\/blood-2015-12-684514","article-title":"Conditional knockout mice demonstrate function of Klf5 as a myeloid transcription factor","volume":"128","author":"Shahrin","year":"2016","journal-title":"Blood"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0790","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1096\/fj.11-200246","article-title":"CCL11 elicits secretion of RNases from mouse eosinophils and their cell-free granules","volume":"26","author":"Shamri","year":"2012","journal-title":"The FASEB Journal"},{"issue":"7","key":"10.1016\/bs.ai.2018.03.001_bb0795","doi-asserted-by":"crossref","first-page":"3734","DOI":"10.4049\/jimmunol.171.7.3734","article-title":"Eosinophil major basic protein stimulates neutrophil superoxide production by a class IA phosphoinositide 3-kinase and protein kinase C-zeta-dependent pathway","volume":"171","author":"Shenoy","year":"2003","journal-title":"Journal of Immunology"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0800","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/all.12570","article-title":"Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation","volume":"70","author":"Simon","year":"2015","journal-title":"Allergy"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0805","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jaci.2010.03.042","article-title":"Refining the definition of hypereosinophilic syndrome","volume":"126","author":"Simon","year":"2010","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0810","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1006659","article-title":"A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma","volume":"13","author":"Smith","year":"2017","journal-title":"PLoS Genetics"},{"key":"10.1016\/bs.ai.2018.03.001_bb0815","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2014.00496","article-title":"Eosinophil secretion of granule-derived cytokines","volume":"5","author":"Spencer","year":"2014","journal-title":"Frontiers in Immunology"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0820","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1189\/jlb.0108058","article-title":"Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially","volume":"85","author":"Spencer","year":"2009","journal-title":"Journal of Leukocyte Biology"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0825","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.jaci.2011.11.044","article-title":"Reslizumab in children and adolescents with eosinophilic esophagitis: Results of a double-blind, randomized, placebo-controlled trial","volume":"129","author":"Spergel","year":"2012","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0830","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.4049\/jimmunol.148.11.3543","article-title":"Apoptosis in human eosinophils\u2014Programmed cell-death in the eosinophil leads to phagocytosis by macrophages and is modulated by Il-5","volume":"148","author":"Stern","year":"1992","journal-title":"Journal of Immunology"},{"issue":"12","key":"10.1016\/bs.ai.2018.03.001_bb0835","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1038\/cdd.2016.73","article-title":"RhoH is a negative regulator of eosinophilopoiesis","volume":"23","author":"Stoeckle","year":"2016","journal-title":"Cell Death and Differentiation"},{"issue":"6","key":"10.1016\/bs.ai.2018.03.001_bb0840","doi-asserted-by":"crossref","first-page":"3472","DOI":"10.4049\/jimmunol.1000730","article-title":"IL-33 exacerbates eosinophil-mediated airway inflammation","volume":"185","author":"Stolarski","year":"2010","journal-title":"Journal of Immunology"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0845","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1365-2249.1991.tb05725.x","article-title":"Effects of IL-5, granulocyte\/macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro","volume":"85","author":"Tai","year":"1991","journal-title":"Clinical and Experimental Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0850","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1084\/jem.181.3.889","article-title":"Multi-colony stimulating activity of interleukin 5 (IL-5) on hematopoietic progenitors from transgenic mice that express IL-5 receptor alpha subunit constitutively","volume":"181","author":"Takagi","year":"1995","journal-title":"The Journal of Experimental Medicine"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0855","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/mi.2015.2","article-title":"Eosinophils in mucosal immune responses","volume":"8","author":"Travers","year":"2015","journal-title":"Mucosal Immunology"},{"issue":"15","key":"10.1016\/bs.ai.2018.03.001_bb0860","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1016\/j.yexcr.2013.07.002","article-title":"Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders","volume":"319","author":"Troeger","year":"2013","journal-title":"Experimental Cell Research"},{"issue":"8","key":"10.1016\/bs.ai.2018.03.001_bb0865","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1101\/gad.12.8.1176","article-title":"Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG","volume":"12","author":"Tsang","year":"1998","journal-title":"Genes & Development"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0870","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0092-8674(00)80318-9","article-title":"FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation","volume":"90","author":"Tsang","year":"1997","journal-title":"Cell"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0875","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jaci.2015.04.041","article-title":"Eosinophil extracellular trap cell death-derived DNA traps: Their presence in secretions and functional attributes","volume":"137","author":"Ueki","year":"2016","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb0880","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1182\/blood-2012-05-432088","article-title":"Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans","volume":"121","author":"Ueki","year":"2013","journal-title":"Blood"},{"issue":"8","key":"10.1016\/bs.ai.2018.03.001_bb0885","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s11882-016-0634-5","article-title":"Eosinophil ETosis and DNA Traps: A new look at eosinophilic inflammation","volume":"16","author":"Ueki","year":"2016","journal-title":"Current Allergy and Asthma Reports"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb0890","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s12016-015-8489-4","article-title":"Eosinophilic gastroenteritis and colitis: A comprehensive review","volume":"50","author":"Uppal","year":"2016","journal-title":"Clinical Reviews in Allergy and Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0895","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.jaci.2012.02.019","article-title":"Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes","volume":"130","author":"Valent","year":"2012","journal-title":"The Journal of Allergy and Clinical Immunology"},{"key":"10.1016\/bs.ai.2018.03.001_bb0900","unstructured":"van Dijk, T. B., Caldenhoven, E., Raaijmakers, J. A., Lammers, J. W., Koenderman, L., & de Groot, R. P. (1998). The role of transcription factor PU.1 in the activity of the intronic enhancer of the eosinophil-derived neurotoxin (RNS2) gene. Blood, 91(6), 2126\u20132132."},{"issue":"20","key":"10.1016\/bs.ai.2018.03.001_bb0905","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1056\/NEJMoa1702079","article-title":"Mepolizumab or placebo for eosinophilic granulomatosis with polyangiitis","volume":"376","author":"Wechsler","year":"2017","journal-title":"The New England Journal of Medicine"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0910","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.jaci.2012.07.027","article-title":"Novel targeted therapies for eosinophilic disorders","volume":"130","author":"Wechsler","year":"2012","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"12","key":"10.1016\/bs.ai.2018.03.001_bb0915","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1038\/nri.2017.95","article-title":"Functions of tissue-resident eosinophils","volume":"17","author":"Weller","year":"2017","journal-title":"Nature Reviews. Immunology"},{"issue":"15","key":"10.1016\/bs.ai.2018.03.001_bb0920","doi-asserted-by":"crossref","first-page":"6067","DOI":"10.1073\/pnas.1220572110","article-title":"Eosinophil adoptive transfer system to directly evaluate pulmonary eosinophil trafficking in vivo","volume":"110","author":"Wen","year":"2013","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0925","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.4049\/jimmunol.1102222","article-title":"The pan-B cell marker CD22 is expressed on gastrointestinal eosinophils and negatively regulates tissue eosinophilia","volume":"188","author":"Wen","year":"2012","journal-title":"Journal of Immunology"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0930","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.jaip.2016.03.020","article-title":"Hypereosinophilia in children and adults: A retrospective comparison","volume":"4","author":"Williams","year":"2016","journal-title":"The Journal of Allergy and Clinical Immunology. In Practice"},{"key":"10.1016\/bs.ai.2018.03.001_bb0935","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.0105-2896.2004.00215.x","article-title":"Interleukin-13 in asthma pathogenesis","volume":"202","author":"Wills-Karp","year":"2004","journal-title":"Immunological Reviews"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0940","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1067\/mai.2001.119411","article-title":"Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma","volume":"108","author":"Woodruff","year":"2001","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"3","key":"10.1016\/bs.ai.2018.03.001_bb0945","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.iac.2015.05.002","article-title":"Eosinophilia in pulmonary disorders","volume":"35","author":"Woolnough","year":"2015","journal-title":"Immunology and Allergy Clinics of North America"},{"issue":"1","key":"10.1016\/bs.ai.2018.03.001_bb0950","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MOH.0b013e3282f13cd2","article-title":"Severe congenital neutropenia and the unfolded protein response","volume":"15","author":"Xia","year":"2008","journal-title":"Current Opinion in Hematology"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0955","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0098139","article-title":"Identification of microRNAs regulating the developmental pathways of bone marrow derived mast cells","volume":"9","author":"Xiang","year":"2014","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/bs.ai.2018.03.001_bb0960","doi-asserted-by":"crossref","first-page":"3447","DOI":"10.1182\/blood.V91.9.3447","article-title":"Mechanisms of transcription in eosinophils: GATA-1, but not GATA-2, transactivates the promoter of the eosinophil granule major basic protein gene","volume":"91","author":"Yamaguchi","year":"1998","journal-title":"Blood"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb0965","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1182\/blood.V94.4.1429","article-title":"C\/EBPbeta and GATA-1 synergistically regulate activity of the eosinophil granule major basic protein promoter: Implication for C\/EBPbeta activity in eosinophil gene expression","volume":"94","author":"Yamaguchi","year":"1999","journal-title":"Blood"},{"issue":"10","key":"10.1016\/bs.ai.2018.03.001_bb0970","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1182\/blood.V78.10.2542.2542","article-title":"Analysis of the survival of mature human eosinophils: Interleukin-5 prevents apoptosis in mature human eosinophils","volume":"78","author":"Yamaguchi","year":"1991","journal-title":"Blood"},{"issue":"24","key":"10.1016\/bs.ai.2018.03.001_bb0975","doi-asserted-by":"crossref","first-page":"13187","DOI":"10.1073\/pnas.94.24.13187","article-title":"Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT\/enhancer binding protein epsilon-deficient mice","volume":"94","author":"Yamanaka","year":"1997","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"10","key":"10.1016\/bs.ai.2018.03.001_bb0980","doi-asserted-by":"crossref","first-page":"6134","DOI":"10.4049\/jimmunol.173.10.6134","article-title":"Human ribonuclease A superfamily members, eosinophil-derived neurotoxin and pancreatic ribonuclease, induce dendritic cell maturation and activation","volume":"173","author":"Yang","year":"2004","journal-title":"Journal of Immunology"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb0985","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0097537","article-title":"Expression profiling of differentiating eosinophils in bone marrow cultures predicts functional links between microRNAs and their target mRNAs","volume":"9","author":"Yang","year":"2014","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/bs.ai.2018.03.001_bb0990","doi-asserted-by":"crossref","first-page":"3396","DOI":"10.1182\/blood-2003-01-0151","article-title":"Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells","volume":"102","author":"Yang","year":"2003","journal-title":"Blood"},{"issue":"13","key":"10.1016\/bs.ai.2018.03.001_bb0995","doi-asserted-by":"crossref","first-page":"9425","DOI":"10.1074\/jbc.275.13.9425","article-title":"Eosinophil-specific regulation of gp91(phox) gene expression by transcription factors GATA-1 and GATA-2","volume":"275","author":"Yang","year":"2000","journal-title":"The Journal of Biological Chemistry"},{"issue":"5","key":"10.1016\/bs.ai.2018.03.001_bb1000","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S1074-7613(00)80414-8","article-title":"Defective B-1 cell development and impaired immunity against angiostrongylus cantonensis in IL-5R alpha-deficient mice","volume":"4","author":"Yoshida","year":"1996","journal-title":"Immunity"},{"issue":"9","key":"10.1016\/bs.ai.2018.03.001_bb1005","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/nm.1855","article-title":"Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense","volume":"14","author":"Yousefi","year":"2008","journal-title":"Nature Medicine"},{"issue":"11","key":"10.1016\/bs.ai.2018.03.001_bb1010","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1084\/jem.20020656","article-title":"Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo","volume":"195","author":"Yu","year":"2002","journal-title":"The Journal of Experimental Medicine"},{"issue":"4","key":"10.1016\/bs.ai.2018.03.001_bb1015","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.iac.2007.09.003","article-title":"Tissue and BAL based biomarkers in asthma","volume":"27","author":"Zhang","year":"2007","journal-title":"Immunology and Allergy Clinics of North America"},{"issue":"2","key":"10.1016\/bs.ai.2018.03.001_bb1020","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1073\/pnas.94.2.569","article-title":"Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice","volume":"94","author":"Zhang","year":"1997","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"}],"container-title":["Advances in Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065277618300142?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065277618300142?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T07:04:58Z","timestamp":1693638298000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0065277618300142"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9780128151884"],"references-count":203,"URL":"https:\/\/doi.org\/10.1016\/bs.ai.2018.03.001","relation":{},"ISSN":["0065-2776"],"issn-type":[{"value":"0065-2776","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}