{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T01:32:27Z","timestamp":1779931947194,"version":"3.53.1"},"reference-count":98,"publisher":"Elsevier","isbn-type":[{"value":"9780128151914","type":"print"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1016\/bs.apar.2018.08.003","type":"book-chapter","created":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T18:26:49Z","timestamp":1536604009000},"page":"73-95","source":"Crossref","is-referenced-by-count":24,"title":["Immune Response to Opisthorchis viverrini Infection and Its Role in Pathology"],"prefix":"10.1016","member":"78","reference":[{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1179\/136485910X12786389891407","article-title":"Induction of immunoglobulin G4 in human filariasis: an indicator of immunoregulation","volume":"104","author":"Adjobimey","year":"2010","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1016\/bs.apar.2018.08.003_bib2","doi-asserted-by":"crossref","first-page":"787","DOI":"10.4269\/ajtmh.1978.27.787","article-title":"Liver changes in hamsters infected\u00a0with a liver fluke of man, Opisthorchis viverrini","volume":"27","author":"Bhamarapravati","year":"1978","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib3","doi-asserted-by":"crossref","first-page":"695","DOI":"10.3347\/kjp.2014.52.6.695","article-title":"Chronic Opisthorchis viverrini infection and associated hepatobiliary disease is associated with iron loaded M2-like macrophages","volume":"52","author":"Bility","year":"2014","journal-title":"Korean J. Parasitol."},{"key":"10.1016\/bs.apar.2018.08.003_bib4","first-page":"135","article-title":"Detection of antibodies in sera from patients with opisthorchiasis","volume":"19","author":"Boonpucknavig","year":"1986","journal-title":"J. Clin. Lab. Immunol."},{"key":"10.1016\/bs.apar.2018.08.003_bib5","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.bbadis.2012.09.014","article-title":"Cytokine mediated tissue fibrosis","volume":"1832","author":"Borthwick","year":"2013","journal-title":"Biochim. Biophys. Acta."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1017\/S0031182010001216","article-title":"Acquired immune heterogeneity and its sources in human helminth infection","volume":"138","author":"Bourke","year":"2011","journal-title":"Parasitology"},{"key":"10.1016\/bs.apar.2018.08.003_bib7","first-page":"413","article-title":"Studies on the chemotherapy of human opisthorchiasis: III. Minimum effective dose of praziquantel","volume":"12","author":"Bunnag","year":"1981","journal-title":"Southeast Asian J. Trop. Med. Pub. Hlth."},{"issue":"4","key":"10.1016\/bs.apar.2018.08.003_bib8","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.celrep.2017.06.087","article-title":"Mass cytometric analysis of HIV entry, replication, and remodeling in tissue CD4+ T cells","volume":"20","author":"Cavrois","year":"2017","journal-title":"Cell Rep."},{"issue":"4","key":"10.1016\/bs.apar.2018.08.003_bib9","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00784-010-0421-y","article-title":"Detection of salivary antibodies to crude antigens of Opisthorchis viverrini in opisthorchiasis and cholangiocarcinoma patients","volume":"15","author":"Chaiyarit","year":"2011","journal-title":"Clin. Oral. Invest."},{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib10","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/0020-7519(88)90111-7","article-title":"Antibodies in serum and bile of hamsters experimentally infected with Opisthorchis viverrini","volume":"18","author":"Chawengkirttikul","year":"1988","journal-title":"Int. J. Parasitol."},{"issue":"15","key":"10.1016\/bs.apar.2018.08.003_bib11","doi-asserted-by":"crossref","first-page":"6958","DOI":"10.1073\/pnas.1001323107","article-title":"A prospective analysis of the Ab response to Plasmodium falciparum before and after\u00a0a\u00a0malaria season by protein microarray","volume":"107","author":"Crompton","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/bs.apar.2018.08.003_bib12","series-title":"Parasite: Immunity and Pathology","first-page":"89","article-title":"Humoral and cellular effector immune responses against parasites","author":"Crook","year":"1990"},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib13","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1756-3305-3-4","article-title":"Schistosomiasis vaccine discovery using immunomics","volume":"28","author":"Driguez","year":"2010","journal-title":"Parasit. Vectors"},{"issue":"Pt 2","key":"10.1016\/bs.apar.2018.08.003_bib14","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1017\/S0031182000062600","article-title":"Opisthorchis viverrini: relationships between egg counts, worms recovered and antibody levels within an endemic community in northeast Thailand","volume":"102","author":"Elkins","year":"1991","journal-title":"Parasitology"},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib15","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.actatropica.2010.01.007","article-title":"Opisthorchis viverrini: evaluation of 28 kDa glutathione S-transferase as diagnostic tool in human opisthorchiasis","volume":"114","author":"Eursitthichai","year":"2010","journal-title":"Acta Trop."},{"key":"10.1016\/bs.apar.2018.08.003_bib16","first-page":"8","article-title":"Serodiagnosis of Opisthorchis viverrini infection by an enzyme immunoassay","volume":"33","author":"Feldheim","year":"1982","journal-title":"Tropenmed. Parasitol."},{"issue":"32","key":"10.1016\/bs.apar.2018.08.003_bib17","doi-asserted-by":"crossref","first-page":"13499","DOI":"10.1073\/pnas.0812080106","article-title":"A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens","volume":"106","author":"Felgner","year":"2009","journal-title":"Proc. Natl. Acad. Sci USA"},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib18","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1017\/S0022149X0000657X","article-title":"Opisthorchis viverrini: partial success in adoptively transferring immunity with spleen cells and serum in the hamster","volume":"54","author":"Flavell","year":"1980","journal-title":"J. Helminthol."},{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib19","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/0035-9203(82)90112-2","article-title":"Acquired resistance to Opisthorchis viverrini in the hamster","volume":"76","author":"Flavell","year":"1982","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib20","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2174\/187153012799279108","article-title":"Wolbachia and its implications for the immunopathology of filariasis","volume":"12","author":"Genchi","year":"2012","journal-title":"Endocr. Metab. Immune Disord. - Drug Targets"},{"issue":"13","key":"10.1016\/bs.apar.2018.08.003_bib21","doi-asserted-by":"crossref","first-page":"92424","DOI":"10.1172\/jci.insight.92424","article-title":"High-dimensional CyTOF analysis of dengue virus-infected human DCs reveals distinct viral signatures","volume":"2","author":"Hamlin","year":"2017","journal-title":"JCI Insight"},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1017\/S0031182000059333","article-title":"Distribution patterns of Opisthorchis viverrini within a human community","volume":"102","author":"Haswell-Elkins","year":"1991","journal-title":"Parasitology"},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib23","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/j.1365-2249.1991.tb08151.x","article-title":"Immune responsiveness and parasite-specific antibody levels in human hepatobiliary disease associated with Opisthorchis viverrini infection","volume":"84","author":"Haswell-Elkins","year":"1991","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/bs.apar.2018.08.003_bib24","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0065-308X(02)52014-5","article-title":"Cytokine-mediated host responses during schistosome infections; walking the fine line between immunological control and immunopathology","volume":"52","author":"Hoffmann","year":"2002","journal-title":"Adv. Parasitol."},{"issue":"8","key":"10.1016\/bs.apar.2018.08.003_bib25","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.4049\/jimmunol.139.8.2794","article-title":"IgG antibody subclasses in human filariasis. Differential subclass recognition of parasite antigens correlates with different clinical manifestations of infection","volume":"139","author":"Hussain","year":"1987","journal-title":"J. Immunol."},{"issue":"8","key":"10.1016\/bs.apar.2018.08.003_bib26","first-page":"439","article-title":"The immunological diagnosis of human opisthorchiasis and the humoral immune response to opisthorchis infection in the hamster","volume":"63","author":"Janechaiwat","year":"1980","journal-title":"J. Med. Assoc. Thai."},{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib27","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1365-3024.1987.tb00536.x","article-title":"Antibody isotypes of immune complexes in schistosomiasis mansoni in Sudan","volume":"9","author":"Jassim","year":"1987","journal-title":"Parasite Immunol."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib28","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.actatropica.2012.01.010","article-title":"Protective immunization of hamsters against Opisthorchis viverrini infection is associated with the reduction of TGF-\u03b2 expression","volume":"122","author":"Jittimanee","year":"2012","journal-title":"Acta Trop."},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib29","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1365-3024.2006.00929.x","article-title":"Cytokine expression in hamsters experimentally infected with Opisthorchis viverrini","volume":"29","author":"Jittimanee","year":"2007","journal-title":"Parasite Immunol."},{"issue":"11","key":"10.1016\/bs.apar.2018.08.003_bib30","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1111\/pim.12358","article-title":"Induction of regulatory T cells by Opisthorchis viverrini","volume":"38","author":"Kaewraemruaen","year":"2016","journal-title":"Parasite Immunol."},{"key":"10.1016\/bs.apar.2018.08.003_bib31","doi-asserted-by":"crossref","first-page":"913","DOI":"10.4269\/ajtmh.1972.21.913","article-title":"Raised level of serum IgE in human helminthiasis","volume":"21","author":"Kajima","year":"1972","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"33","key":"10.1016\/bs.apar.2018.08.003_bib32","doi-asserted-by":"crossref","first-page":"14703","DOI":"10.1073\/pnas.1009080107","article-title":"Dynamic antibody responses to the Mycobacterium tuberculosis proteome","volume":"107","author":"Kunnath-Velayudhan","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/bs.apar.2018.08.003_bib33","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/978-1-4939-7346-0_3","article-title":"Mass cytometry assays for antigen-specific T cells using CyTOF","volume":"1678","author":"Lin","year":"2018","journal-title":"Methods Mol. Biol."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib34","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s12967-018-1528-1","article-title":"Baseline immune profile by CyTOF can predict response to an investigational adjuvanted vaccine in elderly adults","volume":"16","author":"Lingblom","year":"2018","journal-title":"J. Transl. Med."},{"key":"10.1016\/bs.apar.2018.08.003_bib35","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.actatropica.2003.03.001","article-title":"Clinical manifestation of opisthorchiasis and treatment","volume":"88","author":"Mairiang","year":"2003","journal-title":"Acta Trop."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib36","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1440-1746.1992.tb00928.x","article-title":"Relationship between intensity of Opisthorchis viverrini infection and hepatobiliary disease detected by ultrasonography","volume":"7","author":"Mairiang","year":"1992","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib37","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/0035-9203(93)90489-D","article-title":"Reversal of biliary tract abnormalities associated with Opisthorchis viverrini infection\u00a0following praziquantel treatment","volume":"87","author":"Mairiang","year":"1993","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib38","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.parint.2011.07.009","article-title":"Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand","volume":"61","author":"Mairiang","year":"2012","journal-title":"Parasitol. Int."},{"issue":"4","key":"10.1016\/bs.apar.2018.08.003_bib39","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.parint.2016.12.005","article-title":"Ultrasonographic features of hepatobiliary pathology in opisthorchiasis and opisthorchiasis-associated cholangiocarcinoma","volume":"66","author":"Mairiang","year":"2017","journal-title":"Parasitol. Int."},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib40","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.jaci.2016.07.007","article-title":"Regulation of the host immune system by helminth parasites","volume":"138","author":"Maizels","year":"2016","journal-title":"J. Allergy Clin. Immunol."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib41","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1093\/infdis\/jis654","article-title":"T-helper 17 cells are associated with pathology in human schistosomiasis","volume":"207","author":"Mbow","year":"2013","journal-title":"J. Infect. Dis."},{"issue":"3\u20134","key":"10.1016\/bs.apar.2018.08.003_bib42","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1159\/000234213","article-title":"Accessory molecules in T lymphocyte activation","volume":"82","author":"Miller","year":"1987","journal-title":"Int. Arch. Allergy Appl. Immunol."},{"key":"10.1016\/bs.apar.2018.08.003_bib43","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3347\/kjp.1983.21.1.27","article-title":"Elevation of specific IgE antibody in Clonorchis sinensis infection","volume":"21","author":"Min","year":"1983","journal-title":"Korean J. Parasitol."},{"key":"10.1016\/bs.apar.2018.08.003_bib44","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/nri3073","article-title":"Protective and pathogenic functions of macrophage subsets","volume":"11","author":"Murray","year":"2011","journal-title":"Nat. Rev. Immunol."},{"issue":"4","key":"10.1016\/bs.apar.2018.08.003_bib45","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.parint.2010.09.008","article-title":"Opisthorchis viverrini excretory\/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte","volume":"59","author":"Ninlawan","year":"2010","journal-title":"Parasitol. Int."},{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib46","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1038\/mi.2016.69","article-title":"A double edged sword: Schistosoma mansoni Sm29 regulates both Th1 and Th2 responses in inflammatory mucosal diseases","volume":"9","author":"Oliveira","year":"2016","journal-title":"Mucosal Immunol."},{"key":"10.1016\/bs.apar.2018.08.003_bib47","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.4269\/ajtmh.1981.30.1228","article-title":"Detection, quantitation, and specificity of antiparasite IgE antibodies in human schistosomiasis mansoni","volume":"30","author":"Ottesen","year":"1981","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib48","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1017\/S0022149X14000741","article-title":"Immunization and challenge shown by hamsters infected with Opisthorchis viverrini following exposure to gamma-irradiated metacercariae of this carcinogenic liver fluke","volume":"90","author":"Papatpremsiri","year":"2016","journal-title":"J. Helminthol."},{"issue":"Suppl","key":"10.1016\/bs.apar.2018.08.003_bib49","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1017\/S0031182000083384","article-title":"Antigens of parasitic helminths in diagnosis, protection and pathology","volume":"99","author":"Parkhouse","year":"1989","journal-title":"Parasitology"},{"key":"10.1016\/bs.apar.2018.08.003_bib50","first-page":"26","article-title":"Immunopathology of onchocerciasis: a role for eosinophils inonchocercal dermatitis and keratitis","volume":"66","author":"Pearlman","year":"1997","journal-title":"Chem. Immunol."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib51","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.parint.2011.06.014","article-title":"Specific serum IgG, but not IgA, antibody against purified Opisthorchis viverrini antigen associated with hepatobiliary disease and cholangiocarcinoma","volume":"61","author":"Pinlaor","year":"2012","journal-title":"Parasitol. Int."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib52","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.niox.2004.08.004","article-title":"Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: a model of inflammation-mediated carcinogenesis","volume":"11","author":"Pinlaor","year":"2004","journal-title":"Nitric Oxide"},{"issue":"8","key":"10.1016\/bs.apar.2018.08.003_bib53","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1093\/carcin\/bgh157","article-title":"Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase","volume":"25","author":"Pinlaor","year":"2004","journal-title":"Carcinogenesis"},{"issue":"1\u20132","key":"10.1016\/bs.apar.2018.08.003_bib54","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.exppara.2004.07.007","article-title":"Hepatobiliary changes, antibody response, and alteration of liver enzymes in hamsters re-infected with Opisthorchis viverrini","volume":"108","author":"Pinlaor","year":"2004","journal-title":"Exp. Parasitol."},{"issue":"Suppl","key":"10.1016\/bs.apar.2018.08.003_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3347\/kjp.1986.24.Suppl.1","article-title":"The current pathobiology and chemotherapy of clonorchiasis","volume":"24","author":"Rim","year":"1986","journal-title":"Korean J. Parasitol"},{"issue":"7","key":"10.1016\/bs.apar.2018.08.003_bib56","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/pim.12188","article-title":"Plasma IgG autoantibody against actin-related protein 3 in liver fluke Opisthorchis viverrini infection","volume":"37","author":"Rucksaken","year":"2015","journal-title":"Parasite Immunol."},{"key":"10.1016\/bs.apar.2018.08.003_bib57","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1017\/S0031182000075107","article-title":"Field trials in the control of Opisthorchis viverrini with an integrated programme in endemic areas of northeast Thailand","volume":"106","author":"Saowakontha","year":"1993","journal-title":"Parasitology"},{"key":"10.1016\/bs.apar.2018.08.003_bib58","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.coi.2018.03.023","article-title":"Mass cytometry: a powerful tool for dissecting the immune landscape","volume":"51","author":"Simoni","year":"2018","journal-title":"Curr. Opin. Immunol."},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib59","first-page":"489","article-title":"Specific and cross-reactive monoclonal antibodies to the 89-kDa antigen of Opisthorchis viverrini","volume":"23","author":"Sirisinha","year":"1992","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"issue":"4","key":"10.1016\/bs.apar.2018.08.003_bib60","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0020-7519(86)90112-8","article-title":"Complement-mediated killing of Opisthorchis viverrini via activation of the alternative pathway","volume":"16","author":"Sirisinha","year":"1986","journal-title":"Int. J. Parasitol."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib61","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1017\/S0022149X00012049","article-title":"Immunological analysis of opisthorchis and Clonorchis antigens","volume":"64","author":"Sirisinha","year":"1990","journal-title":"J. Helminthol."},{"issue":"Pt 1","key":"10.1016\/bs.apar.2018.08.003_bib62","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1017\/S0031182000057231","article-title":"Attempts to induce protective immunity in hamsters against infection by a liver fluke of man (Opisthorchis viverrini)","volume":"86","author":"Sirisinha","year":"1983","journal-title":"Parasitology"},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib63","first-page":"243","article-title":"Humoral immune responses in hamsters infected with Opisthorchis viverrini","volume":"14","author":"Sirisinha","year":"1983","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"issue":"4","key":"10.1016\/bs.apar.2018.08.003_bib64","first-page":"567","article-title":"Immunization of hamsters against Opisthorchis viverrini infection","volume":"17","author":"Sirisinha","year":"1986","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"10.1016\/bs.apar.2018.08.003_bib65","series-title":"Role of Immune Responses in the Pathogenesis of Cholecystitis in Association with Opisthorchiasis","author":"Sripa","year":"1995"},{"issue":"10","key":"10.1016\/bs.apar.2018.08.003_bib66","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.pt.2012.07.006","article-title":"The\u00a0tumorigenic liver fluke Opisthorchis viverrini\u2013multiple pathways to cancer","volume":"28","author":"Sripa","year":"2012","journal-title":"Trends Parasitol."},{"key":"10.1016\/bs.apar.2018.08.003_bib67","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0065-308X(10)72011-X","article-title":"Food-borne trematodiases in Southeast Asia epidemiology, pathology, clinical manifestation and control","volume":"72","author":"Sripa","year":"2010","journal-title":"Adv. Parasitol."},{"issue":"7","key":"10.1016\/bs.apar.2018.08.003_bib68","doi-asserted-by":"crossref","first-page":"e201","DOI":"10.1371\/journal.pmed.0040201","article-title":"Liver fluke induces cholangiocarcinoma","volume":"4","author":"Sripa","year":"2007","journal-title":"PLoS Med."},{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib69","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0020-7519(00)00054-0","article-title":"Localisation of parasite antigens and inflammatory responses in experimental opisthorchiasis","volume":"30","author":"Sripa","year":"2000","journal-title":"Int. J. Parasitol."},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib70","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1046\/j.1365-3024.2000.00286.x","article-title":"Relationship between parasite-specific antibody responses and\u00a0intensity of Opisthorchis viverrini infection in hamsters","volume":"22","author":"Sripa","year":"2000","journal-title":"Parasite Immunol."},{"issue":"4","key":"10.1016\/bs.apar.2018.08.003_bib71","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1002\/hep.23134","article-title":"Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6","volume":"50","author":"Sripa","year":"2009","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib72","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/MOG.0b013e3282fbf9b3","article-title":"Cholangiocarcinoma: lessons from Thailand","volume":"24","author":"Sripa","year":"2008","journal-title":"Curr. Opin. Gastroenterol."},{"issue":"5","key":"10.1016\/bs.apar.2018.08.003_bib73","doi-asserted-by":"crossref","first-page":"e1654","DOI":"10.1371\/journal.pntd.0001654","article-title":"Elevated plasma IL-6 associates with increased risk of advanced fibrosis and cholangiocarcinoma in individuals infected by Opisthorchis viverrini","volume":"6","author":"Sripa","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib74","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.actatropica.2003.09.007","article-title":"Histological analysis of gallbladder diseases in relation to opisthorchiasis in endemic areas of Thailand","volume":"88","author":"Sripa","year":"2003","journal-title":"Acta Trop."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib75","first-page":"234","article-title":"Enzyme-linked immunosorbent assay for detection of Opisthorchis viverrini infection","volume":"16","author":"Srivatanakul","year":"1985","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib76","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s40425-018-0328-8","article-title":"Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients","volume":"6","author":"Subrahmanyam","year":"2018","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/bs.apar.2018.08.003_bib77","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1099\/00222615-2-3-358","article-title":"The non-antigenicity of intact ova of Clonorchis sinensis","volume":"2","author":"Sun","year":"1969","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/bs.apar.2018.08.003_bib78","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.4269\/ajtmh.1980.29.1223","article-title":"Clonorchiasis: a report of four cases and discussion of unusual manifestation","volume":"29","author":"Sun","year":"1980","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib79","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.parint.2016.10.009","article-title":"Cytokine profiles in Opisthorchis viverrini stimulated peripheral blood mononuclear cells from cholangiocarcinoma patients","volume":"66","author":"Surapaitoon","year":"2017","journal-title":"Parasitol. Int."},{"issue":"3","key":"10.1016\/bs.apar.2018.08.003_bib80","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3347\/kjp.2017.55.3.295","article-title":"Subsets of inflammatory cytokine gene polymorphisms are associated with risk of carcinogenic liver fluke Opisthorchis viverrini-associated advanced periductal fibrosis and cholangiocarcinoma","volume":"55","author":"Surapaitoon","year":"2017","journal-title":"Korean J. Parasitol."},{"key":"10.1016\/bs.apar.2018.08.003_bib81","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/0020-7519(88)90099-9","article-title":"Rate of reinfection by Opisthorchis viverrini in an edemic Northeast Thai community after chemtherapy","volume":"18","author":"Upatham","year":"1988","journal-title":"Int. J. Parastol."},{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib82","doi-asserted-by":"crossref","first-page":"G537","DOI":"10.1152\/ajpgi.00024.2017","article-title":"Helminths in the gastrointestinal tract as modulators of immunity and pathology","volume":"312","author":"Varyani","year":"2017","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib83","doi-asserted-by":"crossref","first-page":"241","DOI":"10.2217\/fmb.09.127","article-title":"Defining the humoral immune response to infectious agents using high-density protein microarrays","volume":"5","author":"Vigil","year":"2010","journal-title":"Future Microbiol."},{"key":"10.1016\/bs.apar.2018.08.003_bib84","series-title":"Progress in Liver Disease","first-page":"537","article-title":"Liver fluke infection and infestation in Southeast Asia","author":"Viranuvatti","year":"1972"},{"key":"10.1016\/bs.apar.2018.08.003_bib85","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1159\/000336717","article-title":"Tissue microenvironments define and get reinforced by macrophage phenotypes in homeostasis or during inflammation, repair and fibrosis","volume":"4","author":"Weidenbusch","year":"2012","journal-title":"J.\u00a0Innate Immun."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib86","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/sj.icb.7100014","article-title":"Immunopathology of schistosomiasis","volume":"85","author":"Wilson","year":"2007","journal-title":"Immunol. Cell Biol."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib87","doi-asserted-by":"crossref","first-page":"356","DOI":"10.4269\/ajtmh.1988.38.356","article-title":"Characterization of humoral immune response in the serum and bile of patients with opisthorchiasis and its application in immunodiagnosis","volume":"38","author":"Wongratanacheewin","year":"1988","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib88","first-page":"109","article-title":"Effect of praziquantel treatment on antibody levels and lymphoproliferative responses in patients with opisthorchiasis","volume":"19","author":"Wongratanacheewin","year":"1988","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"issue":"Pt 1","key":"10.1016\/bs.apar.2018.08.003_bib89","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1017\/S0031182000081701","article-title":"Analysis of Opisthorchis viverrini antigens by immunoprecipitation and polyacrylamide gel electrophoresis","volume":"96","author":"Wongratanacheewin","year":"1988","journal-title":"Parasitology"},{"issue":"6","key":"10.1016\/bs.apar.2018.08.003_bib90","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/0020-7519(91)90085-L","article-title":"Molecular analysis of T and B cell repertoires in mice immunized with Opisthorchis viverrini antigens","volume":"21","author":"Wongratanacheewin","year":"1991","journal-title":"Int. J. Parasitol."},{"issue":"2","key":"10.1016\/bs.apar.2018.08.003_bib91","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1017\/S0022149X00009913","article-title":"Immunodepression in hamsters experimentally infected with Opisthorchis viverrini","volume":"61","author":"Wongratanacheewin","year":"1987","journal-title":"J. Helminthol."},{"issue":"4","key":"10.1016\/bs.apar.2018.08.003_bib92","first-page":"511","article-title":"Analysis of Opisthorchis viverrini antigens: physicochemical characterization and antigen localization","volume":"18","author":"Wongratanacheewin","year":"1987","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"issue":"1","key":"10.1016\/bs.apar.2018.08.003_bib93","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.pharep.2017.07.017","article-title":"Melatonin suppresses eosinophils and Th17 cells in hamsters treated with a combination\u00a0of human liver fluke infection and a chemical carcinogen","volume":"70","author":"Wongsena","year":"2017","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/bs.apar.2018.08.003_bib94","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/nm.2807","article-title":"Mechanisms of fibrosis: therapeutic translation for fibrotic disease","volume":"18","author":"Wynn","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/bs.apar.2018.08.003_bib95","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1146\/annurev.genom.9.081307.164428","article-title":"Infectious disease in the genomic era","volume":"9","author":"Yang","year":"2008","journal-title":"Annu. Rev. Genomics Hum. Genet."},{"key":"10.1016\/bs.apar.2018.08.003_bib96","doi-asserted-by":"crossref","first-page":"4378","DOI":"10.1038\/ncomms5378","article-title":"The Opisthorchis viverrini genome provides insights into life in the bile duct","volume":"5","author":"Young","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/bs.apar.2018.08.003_bib97","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/bs.apar.2018.05.005","article-title":"Opisthorchis viverrini draft genome - biomedical implications and future avenues","volume":"101","author":"Young","year":"2018","journal-title":"Adv. Parasitol."},{"issue":"9","key":"10.1016\/bs.apar.2018.08.003_bib98","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1111\/pim.12090","article-title":"Mucosal immune responses following intestinal nematode infection","volume":"36","author":"Zaph","year":"2014","journal-title":"Parasite Immunol."}],"container-title":["Advances in Parasitology","Asiatic Liver Fluke - From Basic Science to Public Health, Part B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065308X18300563?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065308X18300563?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T20:04:13Z","timestamp":1758744253000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0065308X18300563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9780128151914"],"references-count":98,"URL":"https:\/\/doi.org\/10.1016\/bs.apar.2018.08.003","relation":{},"ISSN":["0065-308X"],"issn-type":[{"value":"0065-308X","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}