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Parasitol."},{"key":"10.1016\/bs.apar.2021.01.002_bb0555","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.12688\/gatesopenres.13067.1","article-title":"The World Health Organization 2030 goals for onchocerciasis: insights and perspectives from mathematical modelling","volume":"3","author":"NTD Modelling Consortium Onchocerciasis Group","year":"2019","journal-title":"Gates Open Res."},{"issue":"6","key":"10.1016\/bs.apar.2021.01.002_bb0560","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1086\/314784","article-title":"Distribution of the blinding and nonblinding strains of Onchocerca volvulus in Nigeria","volume":"179","author":"Ogunrinade","year":"1999","journal-title":"J. Infect. Dis."},{"issue":"1","key":"10.1016\/bs.apar.2021.01.002_bb0565","article-title":"Model-based geostatistical mapping of the prevalence of Onchocerca volvulus in West Africa","volume":"10","author":"O'Hanlon","year":"2016","journal-title":"PLoS Negl. Trop. 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Entomol. M\u00e9d. Parasitol."},{"issue":"2","key":"10.1016\/bs.apar.2021.01.002_bb0585","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1179\/000349802125000718","article-title":"Excess mortality associated with blindness in the onchocerciasis focus of the Mbam Valley, Cameroon","volume":"96","author":"Pion","year":"2002","journal-title":"Ann. Trop. Med. Parasitol."},{"issue":"3","key":"10.1016\/bs.apar.2021.01.002_bb0590","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF00133522","article-title":"Cytotaxonomy of Simulium sanctipauli and Simulium soubrense (Diptera: Simuliidae)","volume":"69","author":"Post","year":"1986","journal-title":"Genetica"},{"issue":"2","key":"10.1016\/bs.apar.2021.01.002_bb0595","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1079\/BER2003228","article-title":"Cytotaxonomy, morphology and molecular systematics of the Bioko form of Simulium yahense (Diptera: Simuliidae)","volume":"93","author":"Post","year":"2003","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/bs.apar.2021.01.002_bb0600","series-title":"Trav. Doc. O.R.S.T.O.M. 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Parasitol."},{"issue":"3","key":"10.1016\/bs.apar.2021.01.002_bb0635","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1080\/00034983.1987.11812118","article-title":"Studies on the dynamics of transmission of onchocerciasis in a Sudan-savanna area of North Cameroon IV. The different exposure to Simulium bites and transmission of boys and girls and men and women, and the resulting manifestations of onchocerciasis","volume":"81","author":"Renz","year":"1987","journal-title":"Ann. Trop. Med. Parasitol."},{"issue":"3","key":"10.1016\/bs.apar.2021.01.002_bb0640","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1080\/00034983.1987.11812119","article-title":"Studies on the dynamics of transmission of onchocerciasis in a Sudan-savanna area of North Cameroon V. What is a tolerable level of Annual Transmission Potential?","volume":"81","author":"Renz","year":"1987","journal-title":"Ann. Trop. Med. 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