{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T09:04:05Z","timestamp":1784019845075,"version":"3.55.0"},"reference-count":87,"publisher":"Elsevier","isbn-type":[{"value":"9780443295645","type":"print"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100019274","name":"National Institute of Mental Health and Neurosciences","doi-asserted-by":"publisher","award":["R01AG060610"],"award-info":[{"award-number":["R01AG060610"]}],"id":[{"id":"10.13039\/100019274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1016\/bs.apcsb.2024.08.002","type":"book-chapter","created":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T01:10:12Z","timestamp":1724461812000},"page":"387-409","source":"Crossref","is-referenced-by-count":8,"title":["Lipid role in synapse and nuclear envelope-associated endocytic pathways in Tauopathy"],"prefix":"10.1016","member":"78","reference":[{"issue":"6","key":"10.1016\/bs.apcsb.2024.08.002_bib1","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0294-16.2016","article-title":"Biomarkers of traumatic brain injury: Temporal changes in body fluids","volume":"3","author":"Adrian","year":"2016","journal-title":"eNeuro"},{"issue":"7","key":"10.1016\/bs.apcsb.2024.08.002_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.110008","article-title":"Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin-mediated endocytosis","volume":"37","author":"Anderson","year":"2021","journal-title":"Cell Reports"},{"issue":"4","key":"10.1016\/bs.apcsb.2024.08.002_bib3","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.3233\/JAD-170900","article-title":"Multi-faceted role of melatonin in neuroprotection and amelioration of tau aggregates in Alzheimer\u2019s disease","volume":"62","author":"Balmik","year":"2018","journal-title":"Journal of Alzheimer's Disease: JAD"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12964-021-00732-z","article-title":"Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer\u2019s disease","volume":"19","author":"Balmik","year":"2021","journal-title":"Cell Communication and Signaling: CCS"},{"issue":"2","key":"10.1016\/bs.apcsb.2024.08.002_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejcb.2022.151202","article-title":"Inter-relationship of histone deacetylase-6 with Tau-cytoskeletal organization and remodeling","volume":"101","author":"Balmik","year":"2022","journal-title":"European Journal of Cell Biology"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib6","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12964-021-00736-9","article-title":"The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau","volume":"19","author":"Balmik","year":"2021","journal-title":"Cell Communication and Signaling: CCS"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0163-7827(01)00016-9","article-title":"Cholesterol and other membrane active sterols: From membrane evolution to \u201crafts\u201d","volume":"41","author":"Barenholz","year":"2002","journal-title":"Progress in Lipid Research"},{"issue":"3","key":"10.1016\/bs.apcsb.2024.08.002_bib8","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1042\/bj3230577","article-title":"Regulated phosphorylation and dephosphorylation of Tau protein: Effects on microtubule interaction, intracellular trafficking and neurodegeneration","volume":"323","author":"Billingsley","year":"1997","journal-title":"Biochemical Journal"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajpath.2019.04.010","article-title":"Apolipoprotein E\/amyloid-\u03b2 complex accumulates in Alzheimer disease cortical synapses via apolipoprotein E receptors and is enhanced by APOE4","author":"Bilousova","year":"2019","journal-title":"The American Journal of Pathology"},{"issue":"4","key":"10.1016\/bs.apcsb.2024.08.002_bib10","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1001\/jamaneurol.2013.5847","article-title":"Amyloid-\u03b2 and Tau: The trigger and bullet in Alzheimer disease pathogenesis","volume":"71","author":"Bloom","year":"2014","journal-title":"JAMA Neurology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib11","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.neuroscience.2020.04.019","article-title":"G-protein coupled receptors and Tau-different roles in Alzheimer\u2019s disease","volume":"438","author":"Chidambaram","year":"2020","journal-title":"Neuroscience"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib12","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s13578-020-00474-4","article-title":"Interaction of Tau with the chemokine receptor, CX3CR1 and its effect on microglial activation, migration and proliferation","volume":"10","author":"Chidambaram","year":"2020","journal-title":"Cell & Bioscience"},{"issue":"2","key":"10.1016\/bs.apcsb.2024.08.002_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejcb.2022.151201","article-title":"G-protein coupled purinergic P2Y12 receptor interacts and internalizes TauRD-mediated by membrane-associated actin cytoskeleton remodeling in microglia","volume":"101","author":"Chidambaram","year":"2022","journal-title":"European Journal of Cell Biology"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib14","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s13578-023-01028-0","article-title":"Microglia degrade Tau oligomers deposit via purinergic P2Y12-associated podosome and filopodia formation and induce chemotaxis","volume":"13","author":"Chinnathambi","year":"2023","journal-title":"Cell Biosci"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib15","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/978-1-0716-3629-9_6","article-title":"Photo-excited dyes: Emerging technique against Tau protein aggregation","volume":"2754","author":"Chinnathambi","year":"2024","journal-title":"Methods in Molecular Biology"},{"issue":"3","key":"10.1016\/bs.apcsb.2024.08.002_bib16","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0169-409X(01)00139-9","article-title":"Cell biology of caveolae and caveolin","volume":"49","author":"Couet","year":"2001","journal-title":"Advanced Drug Delivery Reviews"},{"issue":"46","key":"10.1016\/bs.apcsb.2024.08.002_bib17","doi-asserted-by":"crossref","first-page":"27331","DOI":"10.1039\/D0RA03809A","article-title":"Residue-based propensity of aggregation in the Tau amyloidogenic hexapeptides AcPHF6\u204e and AcPHF6","volume":"10","author":"Dangi","year":"2020","journal-title":"RSC Advances"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib18","doi-asserted-by":"crossref","DOI":"10.1177\/1759091420981204","article-title":"Melatonin reduces GSK3\u03b2-mediated tau phosphorylation, enhances Nrf2 nuclear translocation and anti-inflammation","volume":"12","author":"Das","year":"2020","journal-title":"ASN Neuro"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib19","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12974-019-1694-y","article-title":"Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia","volume":"17","author":"Das","year":"2020","journal-title":"Journal of Neuroinflammation"},{"issue":"19","key":"10.1016\/bs.apcsb.2024.08.002_bib20","doi-asserted-by":"crossref","first-page":"3681","DOI":"10.1007\/s00018-019-03132-2","article-title":"Microglial priming of antigen presentation and adaptive stimulation in Alzheimer\u2019s disease","volume":"76","author":"Das","year":"2019","journal-title":"Cellular and Molecular Life Sciences: CMLS"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib21","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.neuroscience.2020.09.024","article-title":"Actin-mediated microglial chemotaxis via G-protein coupled purinergic receptor in Alzheimer\u2019s disease","volume":"448","author":"Das","year":"2020","journal-title":"Neuroscience"},{"issue":"5","key":"10.1016\/bs.apcsb.2024.08.002_bib22","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.conb.2010.06.008","article-title":"Lipid function at synapses","volume":"20","author":"Davletov","year":"2010","journal-title":"Current Opinion in Neurobiology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib23","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/978-1-0716-3629-9_11","article-title":"Biochemical and biophysical characterization of tau and \u03b1-linolenic acid vesicles in vitro","volume":"2754","author":"Desale","year":"2024","journal-title":"Methods in Molecular Biology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib24","doi-asserted-by":"crossref","unstructured":"Desale, S.E., & Chinnathambi, S. (2020a). Dietary Fatty Acids Mediate the Secondary Messenger Phosphatidylinositol for Microglial Phagocytosis and Migration. In Preprints: Preprints.","DOI":"10.20944\/preprints202007.0532.v1"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib25","doi-asserted-by":"crossref","unstructured":"Desale, S.E., & Chinnathambi, S. (2020b). \u03b1-Linolenic acid modulates phagocytosis of extracellular Tau and induces microglial migration. bioRxiv, 2020.2004.2015.042143. https:\/\/doi.org\/10.1101\/2020.04.15.042143.","DOI":"10.1101\/2020.04.15.042143"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib26","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s12974-020-01742-3","article-title":"Role of dietary fatty acids in microglial polarization in Alzheimer\u2019s disease","volume":"17","author":"Desale","year":"2020","journal-title":"Journal of Neuroinflammation"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib27","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1080\/19336918.2021.1898727","article-title":"Alpha- Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia","volume":"15","author":"Desale","year":"2021","journal-title":"Cell Adhesion & Migration"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib28","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s12964-021-00715-0","article-title":"Phosphoinositides signaling modulates microglial actin remodeling and phagocytosis in Alzheimer\u2019s disease","volume":"19","author":"Desale","year":"2021","journal-title":"Cell Communication and Signaling"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib29","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s43556-021-00036-1","article-title":"G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-\u03b2 in Alzheimer\u2019s disease","volume":"2","author":"Desale","year":"2021","journal-title":"Molecular Biomedicine"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib30","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.ijbiomac.2020.10.226","article-title":"Alpha-Linolenic acid inhibits Tau aggregation and modulates Tau conformation","volume":"166","author":"Desale","year":"2021","journal-title":"International Journal of Biological Macromolecules"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib31","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1146\/annurev.biochem.78.081307.110540","article-title":"Mechanisms of endocytosis","volume":"78","author":"Doherty","year":"2009","journal-title":"Annual Review of Biochemistry"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib32","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-69403-2","article-title":"Photodynamic exposure of Rose-Bengal inhibits Tau aggregation and modulates cytoskeletal network in neuronal cells","volume":"10","author":"Dubey","year":"2020","journal-title":"Scientific Reports"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib33","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijbiomac.2020.02.278","article-title":"Cobalt-based metal complexes prevent Repeat Tau aggregation and nontoxic to neuronal cells","volume":"152","author":"Gorantla","year":"2020","journal-title":"International Journal of Biological Macromolecules"},{"issue":"6","key":"10.1016\/bs.apcsb.2024.08.002_bib34","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1007\/s10571-020-00897-0","article-title":"Autophagic pathways to clear the tau aggregates in Alzheimer\u2019s disease","volume":"41","author":"Gorantla","year":"2021","journal-title":"Cellular and Molecular Neurobiology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib35","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/978-1-4939-6598-4_2","article-title":"Global conformation of tau protein mapped by Raman spectroscopy","volume":"1523","author":"Gorantla","year":"2017","journal-title":"Methods in Molecular Biology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib36","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-6598-4_1","article-title":"Conformational dynamics of intracellular tau protein revealed by CD and SAXS","volume":"1523","author":"Gorantla","year":"2017","journal-title":"Methods in Molecular Biology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22115900","article-title":"Elevating the levels of calcium ions exacerbate Alzheimer\u2019s disease via inducing the production and aggregation of \u03b2-amyloid protein and phosphorylated tau","volume":"22","author":"Guan","year":"2021","journal-title":"International Journal of Molecular Sciences"},{"issue":"9","key":"10.1016\/bs.apcsb.2024.08.002_bib38","doi-asserted-by":"crossref","first-page":"884","DOI":"10.2174\/0929867323666160229113911","article-title":"Amyloid beta (A\u03b2) peptide and factors that play important roles in Alzheimer\u2019s disease","volume":"23","author":"Jamasbi","year":"2016","journal-title":"Current Medicinal Chemistry"},{"issue":"7","key":"10.1016\/bs.apcsb.2024.08.002_bib39","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1111\/j.1582-4934.2009.00754.x","article-title":"Endocytosis via caveolae: Alternative pathway with distinct cellular compartments to avoid lysosomal degradation?","volume":"13","author":"Kiss","year":"2009","journal-title":"Journal of Cellular and Molecular Medicine"},{"issue":"7","key":"10.1016\/bs.apcsb.2024.08.002_bib40","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1242\/jcs.167866","article-title":"Cavin family proteins and the assembly of caveolae","volume":"128","author":"Kovtun","year":"2015","journal-title":"Journal of Cell Science"},{"issue":"3","key":"10.1016\/bs.apcsb.2024.08.002_bib41","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/cr.2010.19","article-title":"Endocytosis unplugged: Multiple ways to enter the cell","volume":"20","author":"Kumari","year":"2010","journal-title":"Cell Research"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib42","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neuron.2016.02.033","article-title":"Membrane lipids in presynaptic function and disease","volume":"90","author":"Lauwers","year":"2016","journal-title":"Neuron"},{"issue":"5","key":"10.1016\/bs.apcsb.2024.08.002_bib43","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1074\/jbc.M111240200","article-title":"Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum","volume":"277","author":"Le","year":"2002","journal-title":"The Journal of Biological Chemistry"},{"issue":"3","key":"10.1016\/bs.apcsb.2024.08.002_bib44","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1152\/jn.00465.2014","article-title":"Postsynaptic mGluR5 promotes evoked AMPAR-mediated synaptic transmission onto neocortical layer 2\/3 pyramidal neurons during development","volume":"113","author":"Loerwald","year":"2015","journal-title":"Journal of Neurophysiology"},{"issue":"10","key":"10.1016\/bs.apcsb.2024.08.002_bib45","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.tcb.2006.08.001","article-title":"Endocytic adaptors: Recruiters, coordinators and regulators","volume":"16","author":"Maldonado-B\u00e1ez","year":"2006","journal-title":"Trends in Cell Biology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib46","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3233\/JAD-130275","article-title":"Abnormal interaction of oligomeric amyloid-\u03b2 with phosphorylated tau: Implications to synaptic dysfunction and neuronal damage","volume":"36","author":"Manczak","year":"2013","journal-title":"Journal of Alzheimer\u2019s Disease"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib47","article-title":"Energy and dynamics of caveolae trafficking","volume":"8","author":"Matthaeus","year":"2020","journal-title":"Frontiers in Cell and Developmental Biology"},{"issue":"6012","key":"10.1016\/bs.apcsb.2024.08.002_bib48","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1126\/science.1197623","article-title":"Decreased clearance of CNS \u03b2-amyloid in Alzheimer\u2019s disease","volume":"330","author":"Mawuenyega","year":"2010","journal-title":"Science (New York, N. Y.)"},{"issue":"8","key":"10.1016\/bs.apcsb.2024.08.002_bib49","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm3151","article-title":"Molecular mechanism and physiological functions of clathrin-mediated endocytosis","volume":"12","author":"McMahon","year":"2011","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib50","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1146\/annurev-biochem-062917-012644","article-title":"Regulation of clathrin-mediated endocytosis","volume":"87","author":"Mettlen","year":"2018","journal-title":"Annual Review of Biochemistry"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib51","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/j.ijbiomac.2020.07.327","article-title":"Role of Tau protein in Alzheimer\u2019s disease: The prime pathological player","volume":"163","author":"Muralidar","year":"2020","journal-title":"International Journal of Biological Macromolecules"},{"issue":"4","key":"10.1016\/bs.apcsb.2024.08.002_bib52","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s10571-020-00883-6","article-title":"Role of microglia in regulating cholesterol and tau pathology in Alzheimer\u2019s disease","volume":"41","author":"Nanjundaiah","year":"2021","journal-title":"Cellular and Molecular Neurobiology"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib53","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1083\/jcb.141.1.101","article-title":"Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium","volume":"141","author":"Oh","year":"1998","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib54","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.jconrel.2020.09.015","article-title":"Role for caveolin-mediated transcytosis in facilitating transport of large cargoes into the brain via ultrasound","volume":"327","author":"Pandit","year":"2020","journal-title":"Journal of Controlled Release"},{"issue":"6","key":"10.1016\/bs.apcsb.2024.08.002_bib55","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.cell.2004.09.003","article-title":"Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic","volume":"118","author":"Pelkmans","year":"2004","journal-title":"Cell"},{"issue":"2","key":"10.1016\/bs.apcsb.2024.08.002_bib56","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1007\/s12035-019-01775-7","article-title":"A perspective: Active role of lipids in neurotransmitter dynamics","volume":"57","author":"Postila","year":"2020","journal-title":"Molecular Neurobiology"},{"issue":"4","key":"10.1016\/bs.apcsb.2024.08.002_bib57","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s00401-013-1182-x","article-title":"Microglia actions in Alzheimer\u2019s disease","volume":"126","author":"Prokop","year":"2013","journal-title":"Acta Neuropathologica"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib58","doi-asserted-by":"crossref","first-page":"975","DOI":"10.3233\/JAD-160612","article-title":"Amyloid-beta and phosphorylated tau accumulations cause abnormalities & synapses of Alzheimer\u2019s disease neurons","volume":"57","author":"Rajmohan","year":"2017","journal-title":"Journal of Alzheimer\u2019s Disease"},{"issue":"2","key":"10.1016\/bs.apcsb.2024.08.002_bib59","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1083\/jcb.200203103","article-title":"A phosphatidylinositol (4,5)-bisphosphate binding site within \u03bc2-adaptin regulates clathrin-mediated endocytosis","volume":"158","author":"Rohde","year":"2002","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib60","doi-asserted-by":"crossref","first-page":"451","DOI":"10.3389\/fnmol.2017.00451","article-title":"Astroglial glutamate signaling and uptake in the hippocampus","volume":"10","author":"Rose","year":"2017","journal-title":"Frontiers in Molecular Neuroscience"},{"issue":"10","key":"10.1016\/bs.apcsb.2024.08.002_bib61","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1177\/153537020122601002","article-title":"Recent advances in membrane microdomains: Rafts, caveolae, and intracellular cholesterol trafficking","volume":"226","author":"Schroeder","year":"2001","journal-title":"Experimental Biology and Medicine"},{"issue":"4","key":"10.1016\/bs.apcsb.2024.08.002_bib62","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19040998","article-title":"The neurotoxic role of extracellular tau protein","volume":"19","author":"Sebasti\u00e1n-Serrano","year":"2018","journal-title":"International Journal of Molecular Sciences"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib63","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.680301","article-title":"Astrocyte-neuron signaling in synaptogenesis","volume":"9","author":"Shan","year":"2021","journal-title":"Frontiers in Cell and Developmental Biology"},{"issue":"5","key":"10.1016\/bs.apcsb.2024.08.002_bib64","doi-asserted-by":"crossref","first-page":"L843","DOI":"10.1152\/ajplung.1998.275.5.L843","article-title":"Role of plasmalemmal caveolae in signal transduction","volume":"275","author":"Shaul","year":"1998","journal-title":"American Journal of\u00a0Physiology-Lung Cellular and Molecular Physiology"},{"issue":"7","key":"10.1016\/bs.apcsb.2024.08.002_bib65","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1002\/prot.23033","article-title":"Structural memory of natively unfolded Tau protein detected by small-angle X-ray scattering","volume":"79","author":"Shkumatov","year":"2011","journal-title":"Proteins"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib66","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.cell.2010.12.031","article-title":"Cells respond to mechanical stress by rapid disassembly of caveolae","volume":"144","author":"Sinha","year":"2011","journal-title":"Cell"},{"issue":"5","key":"10.1016\/bs.apcsb.2024.08.002_bib67","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1083\/jcb.127.5.1185","article-title":"Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation","volume":"127","author":"Smart","year":"1994","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib68","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3389\/fmolb.2017.00072","article-title":"Weak molecular interactions in clathrin-mediated endocytosis","volume":"4","author":"Smith","year":"2017","journal-title":"Frontiers in Molecular Biosciences"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib69","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2019.108119","article-title":"Baicalein suppresses Repeat Tau fibrillization by sequestering oligomers","volume":"675","author":"Sonawane","year":"2019","journal-title":"Archives of Biochemistry and Biophysics"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib70","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-69429-6","article-title":"EGCG impedes human Tau aggregation and interacts with Tau","volume":"10","author":"Sonawane","year":"2020","journal-title":"Scientific Reports"},{"issue":"4","key":"10.1016\/bs.apcsb.2024.08.002_bib71","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1007\/s12031-018-1111-5","article-title":"Prion-like propagation of post-translationally modified tau in Alzheimer\u2019s disease: A hypothesis","volume":"65","author":"Sonawane","year":"2018","journal-title":"Journal of Molecular Neuroscience: MN"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib72","series-title":"Alzheimer\u2019s disease: Recent findings in pathophysiology, diagnostic and therapeutic modalities","article-title":"Alzheimer\u2019s disease pathology: A tau perspective","author":"Sonawane","year":"2022"},{"issue":"4","key":"10.1016\/bs.apcsb.2024.08.002_bib73","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.ceb.2004.06.001","article-title":"Cargo recognition during clathrin-mediated endocytosis: A team effort","volume":"16","author":"Sorkin","year":"2004","journal-title":"Current Opinion in Cell Biology"},{"issue":"14","key":"10.1016\/bs.apcsb.2024.08.002_bib74","doi-asserted-by":"crossref","first-page":"4845","DOI":"10.1523\/JNEUROSCI.5825-09.2010","article-title":"A mouse model of amyloid \u03b2 oligomers: Their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo","volume":"30","author":"Tomiyama","year":"2010","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib75","first-page":"15","article-title":"Hyperphosphorylated human tau accumulates at the synapse, localizing on synaptic mitochondrial outer membranes and disrupting respiration in a mouse model of tauopathy","author":"Trease","year":"2022","journal-title":"Frontiers in Molecular Neuroscience"},{"issue":"42","key":"10.1016\/bs.apcsb.2024.08.002_bib76","doi-asserted-by":"crossref","first-page":"14234","DOI":"10.1523\/JNEUROSCI.1523-15.2015","article-title":"Internalized tau oligomers cause neurodegeneration by inducing accumulation of pathogenic tau in human neurons derived from induced pluripotent stem cells","volume":"35","author":"Usenovic","year":"2015","journal-title":"The Journal of Neuroscience"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib77","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s40478-019-0754-y","article-title":"Intersection of pathological Tau and microglia at the synapse","volume":"7","author":"Vogels","year":"2019","journal-title":"Acta Neuropathologica Communications"},{"issue":"2","key":"10.1016\/bs.apcsb.2024.08.002_bib78","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1042\/BST20130270","article-title":"Cavin-1: Caveolae-dependent signalling and cardiovascular disease","volume":"42","author":"Williams","year":"2014","journal-title":"Biochemical Society Transactions"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib79","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s40035-021-00270-1","article-title":"The role of pathological Tau in synaptic dysfunction in Alzheimer\u2019s diseases","volume":"10","author":"Wu","year":"2021","journal-title":"Translational Neurodegeneration"},{"issue":"14","key":"10.1016\/bs.apcsb.2024.08.002_bib80","doi-asserted-by":"crossref","first-page":"9129","DOI":"10.1074\/jbc.274.14.9129","article-title":"Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar\/lysosomal membrane trafficking pathways","volume":"274","author":"Wurmser","year":"1999","journal-title":"The Journal of Biological Chemistry"},{"issue":"25","key":"10.1016\/bs.apcsb.2024.08.002_bib81","doi-asserted-by":"crossref","first-page":"21279","DOI":"10.1074\/jbc.M111.338376","article-title":"Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis","volume":"287","author":"Xiao","year":"2012","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib82","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.neurobiolaging.2017.03.021","article-title":"Immune hyperreactivity of A\u03b2 plaque-associated microglia in Alzheimer\u2019s disease","volume":"55","author":"Yin","year":"2017","journal-title":"Neurobiology of Aging"},{"issue":"1","key":"10.1016\/bs.apcsb.2024.08.002_bib83","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s11357-023-00923-1","article-title":"Endocytosis and Alzheimer\u2019s disease","volume":"46","author":"Zadka","year":"2024","journal-title":"Geroscience"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib84","doi-asserted-by":"crossref","first-page":"11938","DOI":"10.1523\/JNEUROSCI.2357-10.2010","article-title":"A\u03b2 oligomers cause localized Ca2+ elevation, missorting of endogenous tau into dendrites, tau phosphorylation, and destruction of microtubules and spines","volume":"30","author":"Zempel","year":"2010","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib85","article-title":"Role of A\u03b2 in Alzheimer\u2019s-related synaptic dysfunction","volume":"10","author":"Zhang","year":"2022","journal-title":"Frontiers in Cell and Developmental Biology"},{"issue":"9","key":"10.1016\/bs.apcsb.2024.08.002_bib86","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.7150\/ijbs.57078","article-title":"Interaction between A\u03b2 and Tau in the pathogenesis of Alzheimer\u2019s disease [review]","volume":"17","author":"Zhang","year":"2021","journal-title":"International Journal of Biological Sciences"},{"key":"10.1016\/bs.apcsb.2024.08.002_bib87","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3389\/fnsyn.2013.00009","article-title":"Synaptic membrane rafts: Traffic lights for local neurotrophin signaling?","volume":"5","author":"Zonta","year":"2013","journal-title":"Frontiers in Synaptic Neuroscience"}],"container-title":["Advances in Protein Chemistry and Structural Biology","Nuclear Proteins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876162324000774?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1876162324000774?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T23:57:13Z","timestamp":1762559833000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1876162324000774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9780443295645"],"references-count":87,"URL":"https:\/\/doi.org\/10.1016\/bs.apcsb.2024.08.002","relation":{},"ISSN":["1876-1623"],"issn-type":[{"value":"1876-1623","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]}}}