{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:07:40Z","timestamp":1790662060974,"version":"4.1.0"},"reference-count":112,"publisher":"Elsevier","isbn-type":[{"value":"9780128140871","type":"print"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1016\/bs.apha.2017.08.005","type":"book-chapter","created":{"date-parts":[[2017,11,8]],"date-time":"2017-11-08T17:00:42Z","timestamp":1510160442000},"page":"235-260","source":"Crossref","is-referenced-by-count":80,"title":["Anti-NMDA Receptor Encephalitis: Clinical Features and Basic Mechanisms"],"prefix":"10.1016","author":[{"given":"David R.","family":"Lynch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Rattelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi Na","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kylie","family":"Roslin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy J.","family":"Gleichman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica A.","family":"Panzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/bs.apha.2017.08.005_bb0010","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1002\/acn3.100","article-title":"Pediatric anti-NMDA receptor encephalitis is seasonal","volume":"1","author":"Adang","year":"2014","journal-title":"Annals of Clinical Translational Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0015","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1212\/WNL.0000000000002809","article-title":"Anti-NMDA receptor antibody encephalitis and neuroendocrine pancreatic tumor: Causal link?","volume":"87","author":"Afanasiev","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0020","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1007\/s00415-011-5982-4","article-title":"Paraneoplastic anti-NMDAR encephalitis: Long term follow-up reveals persistent serum antibodies","volume":"258","author":"Alexopoulos","year":"2011","journal-title":"Journal of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0025","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.jpeds.2012.10.011","article-title":"Spanish anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis work group. Pediatric anti-N-methyl-d-aspartate receptor encephalitis-clinical analysis and novel findings in a series of 20 patients","volume":"162","author":"Armangue","year":"2013","journal-title":"The Journal of Pediatrics"},{"key":"10.1016\/bs.apha.2017.08.005_bb0030","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.msard.2016.12.009","article-title":"Antecedent anti-NMDA receptor encephalitis in two patients with multiple sclerosis","volume":"12","author":"Baheerathan","year":"2017","journal-title":"Multiple Sclerosis and Related Disorders"},{"key":"10.1016\/bs.apha.2017.08.005_bb0035","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1002\/mds.25354","article-title":"The spectrum of movement disorders in children with anti-NMDA receptor encephalitis","volume":"28","author":"Baizabal-Carvallo","year":"2013","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.apha.2017.08.005_bb0040","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.coph.2014.12.004","article-title":"The NMDA receptor \u2018glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond","volume":"20","author":"Balu","year":"2015","journal-title":"Current Opinion in Pharmacology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0045","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0149-7634(96)00038-3","article-title":"Modulation of levodopa-induced motor response complications by NMDA antagonists in Parkinson's disease","volume":"21","author":"Blanchet","year":"1997","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/bs.apha.2017.08.005_bb0050","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1212\/WNL.0b013e31820e7b8d","article-title":"GABA(B) receptor antibodies in limbic encephalitis and anti-GAD-associated neurologic disorders","volume":"76","author":"Boronat","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0055","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.pediatrneurol.2009.10.003","article-title":"Anti-N-methyl-d-aspartate receptor encephalitis: Early treatment is beneficial","volume":"42","author":"Breese","year":"2010","journal-title":"Pediatric Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0060","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1111\/dmcn.12411","article-title":"Does early treatment improve outcomes in N-methyl-d-aspartate receptor encephalitis?","volume":"56","author":"Byrne","year":"2014","journal-title":"Developmental Medicine and Child Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0065","article-title":"All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class","author":"Castillo-G\u00f3mez","year":"2016","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/bs.apha.2017.08.005_bb0070","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/ane.12723","article-title":"Risk factors for mortality in patients with anti-NMDA receptor encephalitis","volume":"136","author":"Chi","year":"2017","journal-title":"Acta Neurologica Scandinavica"},{"key":"10.1016\/bs.apha.2017.08.005_bb0075","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1093\/schbul\/sbs076","article-title":"NMDA receptor and schizophrenia: A brief history","volume":"38","author":"Coyle","year":"2012","journal-title":"Schizophrenia Bulletin"},{"key":"10.1016\/bs.apha.2017.08.005_bb0080","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S0140-6736(11)60548-5","article-title":"Late onset autism and anti-NMDA-receptor encephalitis","volume":"378","author":"Creten","year":"2011","journal-title":"The Lancet"},{"key":"10.1016\/bs.apha.2017.08.005_bb0085","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/dmcn.12036","article-title":"Cerebrospinal fluid CD19(+) B-cell expansion in N-methyl-d-aspartate receptor encephalitis","volume":"55","author":"Dale","year":"2013","journal-title":"Developmental Medicine and Child Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0090","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S1474-4422(08)70224-2","article-title":"Anti-NMDA-receptor encephalitis: Case series and analysis of the effects of antibodies","volume":"7","author":"Dalmau","year":"2008","journal-title":"Lancet Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0095","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S1474-4422(10)70253-2","article-title":"Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis","volume":"10","author":"Dalmau","year":"2011","journal-title":"Lancet Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0100","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/ana.21050","article-title":"Paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis associated with ovarian teratoma","volume":"61","author":"Dalmau","year":"2007","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0105","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/B978-0-444-63432-0.00012-8","article-title":"Anti-NMDAR encephalitis and other glutamate and GABA receptor antibody encephalopathies","volume":"133","author":"De Bruijn","year":"2016","journal-title":"Handbook of Clinical Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0110","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1002\/jca.21363","article-title":"Intravenous methylprednisolone versus therapeutic plasma exchange for treatment of anti-N-methyl-d-aspartate receptor antibody encephalitis: A retrospective review","volume":"30","author":"DeSena","year":"2015","journal-title":"Journal of Clinical Apheresis"},{"key":"10.1016\/bs.apha.2017.08.005_bb0115","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1001\/jamapsychiatry.2015.0526","article-title":"European consortium of autoimmune mental disorders (CAIMED). Absence of N-methyl-d-aspartate receptor IgG autoantibodies in schizophrenia: The importance of cross-validation studies","volume":"72","author":"de Witte","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/bs.apha.2017.08.005_bb0120","article-title":"CSF IgA NMDAR antibodies are potential biomarkers for teratomas in anti-NMDAR encephalitis","volume":"2","author":"Desestret","year":"2015","journal-title":"Neurology: Neuroimmunology & Neuroinflammation"},{"key":"10.1016\/bs.apha.2017.08.005_bb0125","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/acn3.120","article-title":"High prevalence of NMDA receptor IgA\/IgM antibodies in different dementia types","volume":"1","author":"Doss","year":"2014","journal-title":"Annals of Clinical Translational Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0130","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1007\/s00415-012-6457-y","article-title":"Spontaneous recovery from anti-NMDAR encephalitis","volume":"259","author":"Evoli","year":"2012","journal-title":"Journal of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0135","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/ana.21756","article-title":"Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis in children and adolescents","volume":"66","author":"Florance","year":"2009","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0140","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0896-6273(94)90350-6","article-title":"Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death","volume":"13","author":"Forrest","year":"1994","journal-title":"Neuron"},{"key":"10.1016\/bs.apha.2017.08.005_bb0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0003347","article-title":"Serum and cerebrospinal fluid autoantibodies in patients with neuropsychiatric lupus erythematosus. Implications for diagnosis and pathogenesis","volume":"3","author":"Fragoso-Loyo","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/bs.apha.2017.08.005_bb0150","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1212\/WNL.0b013e31822cfc6b","article-title":"Analysis of relapses in anti-NMDAR encephalitis","volume":"77","author":"Gabilondo","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0155","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1093\/cid\/cir1038","article-title":"The frequency of autoimmune N-methyl-d-aspartate receptor encephalitis surpasses that of individual viral etiologies in young individuals enrolled in the California Encephalitis Project","volume":"54","author":"Gable","year":"2012","journal-title":"Clinical Infectious Diseases"},{"key":"10.1016\/bs.apha.2017.08.005_bb0160","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0896-6273(95)90076-4","article-title":"Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS","volume":"15","author":"Geiger","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/bs.apha.2017.08.005_bb0165","doi-asserted-by":"crossref","first-page":"e258","DOI":"10.1097\/INF.0000000000001205","article-title":"Anti-N-methyl-d-aspartate receptor antibody mediated neurologic relapse post herpes simplex encephalitis: A case series","volume":"35","author":"Geoghegan","year":"2016","journal-title":"The Pediatric Infectious Disease Journal"},{"key":"10.1016\/bs.apha.2017.08.005_bb0170","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/acn3.43","article-title":"Antigenic and mechanistic characterization of anti-AMPA receptor encephalitis","volume":"1","author":"Gleichman","year":"2014","journal-title":"Annals of Clinical Translational Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0175","doi-asserted-by":"crossref","first-page":"11082","DOI":"10.1523\/JNEUROSCI.0064-12.2012","article-title":"Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain","volume":"32","author":"Gleichman","year":"2012","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/bs.apha.2017.08.005_bb0180","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S1474-4422(13)70282-5","article-title":"Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: A retrospective study","volume":"13","author":"Gresa-Arribas","year":"2014","journal-title":"The Lancet. Neurology"},{"issue":"4","key":"10.1016\/bs.apha.2017.08.005_bb0185","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/j.jpeds.2013.06.079","article-title":"Anti-N-methyl-d-aspartate receptor encephalitis and parvovirus B19: A possible link?","volume":"163","author":"Grillo","year":"2013","journal-title":"The Journal of Pediatrics"},{"key":"10.1016\/bs.apha.2017.08.005_bb9000","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.pediatrneurol.2016.10.001","article-title":"Anti-N-methyl-D-aspartate receptor encephalitis and Rasmussen-like syndrome: An association?","volume":"66","author":"Gurcharran","year":"2017","journal-title":"Pediatric Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0190","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jneuroim.2013.09.017","article-title":"Rituximab ameliorates anti-N-methyl-d-aspartate receptor encephalitis by removal of short-lived plasmablasts","volume":"265","author":"Hachiya","year":"2013","journal-title":"Journal of Neuroimmunology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0195","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1002\/mds.25626","article-title":"N-Methyl-d-aspartate receptor antibodies in post-herpes simplex virus encephalitis neurological relapse","volume":"29","author":"Hacohen","year":"2014","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.apha.2017.08.005_bb0200","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1001\/jamaneurol.2013.585","article-title":"Persistent intrathecal antibody synthesis 15 years after recovering from anti-N-methyl-d-aspartate receptor encephalitis","volume":"70","author":"Hansen","year":"2013","journal-title":"JAMA Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0205","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1007\/s00415-011-5917-0","article-title":"Anti-N-methyl-d-aspartate receptor encephalitis associated with carcinosarcoma with neuroendocrine differentiation of the uterus","volume":"258","author":"Hara","year":"2011","journal-title":"Journal of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0210","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1002\/art.22030","article-title":"Relationship between serum NR2a antibodies and cognitive dysfunction in systemic lupus erythematosus","volume":"54","author":"Harrison","year":"2006","journal-title":"Arthritis and Rheumatism"},{"key":"10.1016\/bs.apha.2017.08.005_bb0215","doi-asserted-by":"crossref","first-page":"251","DOI":"10.5414\/NP300666","article-title":"Clinical neuropathology practice guide 4-2013: Post-herpes simplex encephalitis: N-methyl-d-aspartate receptor antibodies are part of the problem","volume":"32","author":"H\u00f6ftberger","year":"2013","journal-title":"Clinical Neuropathology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0220","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1212\/WNL.0b013e3182a9585f","article-title":"Encephalitis and GABAB receptor antibodies: Novel findings in a new case series of 20 patients","volume":"81","author":"H\u00f6ftberger","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0225","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1212\/WNL.0000000000001682","article-title":"Encephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients","volume":"84","author":"H\u00f6ftberger","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0230","doi-asserted-by":"crossref","first-page":"5866","DOI":"10.1523\/JNEUROSCI.0167-10.2010","article-title":"Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis","volume":"30","author":"Hughes","year":"2010","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/bs.apha.2017.08.005_bb0235","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3947\/ic.2015.47.2.129","article-title":"Fever of unknown origin: An unusual presentation of anti-N-methyl-d-aspartate receptor encephalitis","volume":"47","author":"Hur","year":"2015","journal-title":"Infection & Chemotherapy"},{"key":"10.1016\/bs.apha.2017.08.005_bb0240","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1212\/01.wnl.0000278388.90370.c3","article-title":"Anti-NMDA receptor encephalitis in Japan: Long-term outcome without tumor removal","volume":"70","author":"Iizuka","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0245","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.2169\/internalmedicine.51.6874","article-title":"Rituximab used successfully in the treatment of anti-NMDA receptor encephalitis","volume":"51","author":"Ikeguchi","year":"2012","journal-title":"Internal Medicine"},{"key":"10.1016\/bs.apha.2017.08.005_bb0250","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1007\/s13760-015-0468-2","article-title":"Anti-NMDA receptor encephalitis possibly triggered by measles virus","volume":"115","author":"Ioannidis","year":"2015","journal-title":"Acta Neurologica Belgica"},{"key":"10.1016\/bs.apha.2017.08.005_bb0255","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1212\/01.wnl.0000336648.43562.59","article-title":"Response of anti-NMDA receptor encephalitis without tumor to immunotherapy including rituximab","volume":"71","author":"Ishiura","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0260","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/s12974-015-0356-y","article-title":"\u2018Medusa-head ataxia': The expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj\/ITPR1 and anti-CARP VIII","volume":"12","author":"Jarius","year":"2015","journal-title":"Journal of Neuroinflammation"},{"key":"10.1016\/bs.apha.2017.08.005_bb0265","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1176\/ajp.148.10.1301","article-title":"Recent advances in the phencyclidine model of schizophrenia","volume":"148","author":"Javitt","year":"1991","journal-title":"The American Journal of Psychiatry"},{"key":"10.1016\/bs.apha.2017.08.005_bb0270","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.clim.2016.03.011","article-title":"A case of anti-NMDA receptor encephalitis in a woman with a NMDA-R(+) small cell lung carcinoma (SCLC)","volume":"166\u2013167","author":"Jeraiby","year":"2016","journal-title":"Clinical Immunology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0275","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1212\/WNL.0b013e3181f8831a","article-title":"Anti-NMDA receptor encephalitis causing prolonged nonconvulsive status epilepticus","volume":"75","author":"Johnson","year":"2010","journal-title":"Neurology"},{"issue":"9","key":"10.1016\/bs.apha.2017.08.005_bb0280","doi-asserted-by":"crossref","first-page":"673","DOI":"10.2169\/internalmedicine.48.1898","article-title":"Nationwide survey of acute juvenile female non-herpetic encephalitis in Japan: Relationship to anti-N-methyl-d-aspartate receptor encephalitis","volume":"48","author":"Kamei","year":"2009","journal-title":"Internal Medicine"},{"key":"10.1016\/bs.apha.2017.08.005_bb0285","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ejpn.2011.07.005","article-title":"Successful treatment of two paediatric cases of anti-NMDA receptor encephalitis with cyclophosphamide: The need for early aggressive immunotherapy in tumour negative paediatric patients","volume":"16","author":"Kashyape","year":"2012","journal-title":"European Journal of Paediatric Neurology"},{"issue":"9","key":"10.1016\/bs.apha.2017.08.005_bb0290","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1001\/jamaneurol.2013.3216","article-title":"Frequency and characteristics of isolated psychiatric episodes in anti-N-methyl-d-aspartate receptor encephalitis","volume":"70","author":"Kayser","year":"2013","journal-title":"JAMA Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0295","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1093\/brain\/aww208","article-title":"Human cerebrospinal fluid monoclonal N-methyl-d-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis","volume":"139","author":"Kreye","year":"2016","journal-title":"Brain"},{"key":"10.1016\/bs.apha.2017.08.005_bb9005","doi-asserted-by":"crossref","first-page":"8648","DOI":"10.1073\/pnas.93.16.8648","article-title":"Probing the pore region of recombinant N-methyl-D-aspartate channels using external and internal magnesium block","volume":"93","author":"Kupper","year":"1996","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/bs.apha.2017.08.005_bb0300","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.ejpn.2012.03.004","article-title":"Anti-NMDA receptor encephalitis: The importance of early diagnosis and aggressive immunotherapy in tumor negative pediatric patients","volume":"16","author":"Kurian","year":"2012","journal-title":"European Journal of Paediatric Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0305","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1001\/archneurol.2009.299","article-title":"Opsoclonus-myoclonus syndrome in anti-N-methyl-d-aspartate receptor encephalitis","volume":"67","author":"Kurian","year":"2010","journal-title":"Archives of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0310","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1002\/mds.25510","article-title":"Anti-N-methyl-d-aspartate-glutamic-receptor encephalitis presenting as paroxysmal exercise-induced foot weakness","volume":"28","author":"Labate","year":"2013","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.apha.2017.08.005_bb0315","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/ana.21589","article-title":"AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location","volume":"65","author":"Lai","year":"2009","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0320","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1212\/WNL.0b013e3182364a44","article-title":"Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndrome","volume":"77","author":"Lancaster","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0325","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.1002\/art.22031","article-title":"Anti-N-methyl-d-aspartate receptor antibodies, cognitive dysfunction, and depression in systemic lupus erythematosus","volume":"54","author":"Lapteva","year":"2006","journal-title":"Arthritis and Rheumatism"},{"key":"10.1016\/bs.apha.2017.08.005_bb0330","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1212\/WNL.0b013e3182a9f531","article-title":"Herpes simplexvirus-1 encephalitis can trigger anti-NMDA receptor encephalitis: Case report","volume":"81","author":"Leypoldt","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0335","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2174\/1389450013348434","article-title":"NMDA receptor pharmacology: Perspectives from molecular biology","volume":"2","author":"Lynch","year":"2001","journal-title":"Current Drug Targets"},{"key":"10.1016\/bs.apha.2017.08.005_bb0340","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1124\/jpet.300.3.717","article-title":"Excitotoxicity: Perspectives based on N-methyl-d-aspartate receptor subtypes","volume":"300","author":"Lynch","year":"2002","journal-title":"The Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/bs.apha.2017.08.005_bb9010","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1750-1172-5-31","article-title":"In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: Further evidence of synaptic glutamatergic dysfunction","volume":"26","author":"Manto","year":"2010","journal-title":"Orphanet Journal of Rare Diseases"},{"key":"10.1016\/bs.apha.2017.08.005_bb0345","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1212\/WNL.0b013e318228c136","article-title":"Analysis of complement and plasma cells in the brain of patients with anti-NMDAR encephalitis","volume":"77","author":"Martinez-Hernandez","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb9025","first-page":"1","article-title":"Cognitive outcomes following anti-N-methyl-D-aspartate receptor encephalitis: A systematic review","volume":"6","author":"McKeon","year":"2017","journal-title":"Journal of Clinical and Experimental Neuropsychology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0350","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1007\/s00787-015-0682-8","article-title":"Anti-NMDA receptor encephalitis presenting as atypical anorexia nervosa: An adolescent case report","volume":"24","author":"Mechelhoff","year":"2015","journal-title":"European Child & Adolescent Psychiatry"},{"key":"10.1016\/bs.apha.2017.08.005_bb0355","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1093\/brain\/aws092","article-title":"Disrupted surface cross-talk between NMDA and Ephrin-B2receptors in anti-NMDA encephalitis","volume":"135","author":"Mikasova","year":"2012","journal-title":"Brain"},{"key":"10.1016\/bs.apha.2017.08.005_bb9015","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1126\/science.256.5060.1217","article-title":"Heteromeric NMDA receptors: Molecular and functional distinction of subtypes","volume":"256","author":"Monyer","year":"1992","journal-title":"Science"},{"key":"10.1016\/bs.apha.2017.08.005_bb0360","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/ana.24195","article-title":"Acute mechanisms underlying antibody effects in anti-N-methyl-d-aspartate receptor encephalitis","volume":"76","author":"Moscato","year":"2014","journal-title":"Annals of Neurology"},{"issue":"8","key":"10.1016\/bs.apha.2017.08.005_bb0365","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/dmcn.13448","article-title":"Herpes simplex virus-induced anti-N-methyl-d-aspartate receptor encephalitis: A systematic literature review with analysis of 43 cases","volume":"59","author":"Nosadini","year":"2017","journal-title":"Developmental Medicine and Child Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0370","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1007\/s00702-013-1152-4","article-title":"Glutamatergic autoencephalitides: An emerging field","volume":"121","author":"Panzer","year":"2014","journal-title":"Journal of Neural Transmission"},{"key":"10.1016\/bs.apha.2017.08.005_bb0375","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.cell.2012.06.029","article-title":"Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists","volume":"150","author":"Papouin","year":"2012","journal-title":"Cell"},{"key":"10.1016\/bs.apha.2017.08.005_bb0380","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1002\/ana.24293","article-title":"Cellular plasticity induced by anti-\u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor encephalitis antibodies","volume":"77","author":"Peng","year":"2015","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0385","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S1474-4422(13)70299-0","article-title":"Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: A case series, characterisation of the antigen, and analysis of the effects of antibodies","volume":"13","author":"Petit-Pedrol","year":"2014","journal-title":"The Lancet Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0390","doi-asserted-by":"crossref","first-page":"3231","DOI":"10.1007\/s00705-016-3002-9","article-title":"A new densovirus in cerebrospinal fluid from a case of anti-NMDA-receptor encephalitis","volume":"161","author":"Phan","year":"2016","journal-title":"Archives of Virology"},{"key":"10.1016\/bs.apha.2017.08.005_bb9020","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/ana.24721","article-title":"Ephrin-B2 prevents N-methyl-D-aspartate receptor antibody effects on memory and neuroplasticity","volume":"80","author":"Planagum\u00e0","year":"2016","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0395","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.pediatrneurol.2015.07.010","article-title":"Pediatric opsoclonus-myoclonus-ataxia syndrome associated with anti-N-methyl-d-aspartate receptor encephalitis","volume":"53","author":"Player","year":"2015","journal-title":"Pediatric Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0400","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1017\/S003329171300295X","article-title":"Prevalence of anti-N-methyl-d-aspartate (NMDA) receptor antibodies in patients with schizophrenia and related psychoses: A systematic review and meta-analysis","volume":"44","author":"Pollak","year":"2014","journal-title":"Psychological Medicine"},{"issue":"75","key":"10.1016\/bs.apha.2017.08.005_bb0405","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1212\/WNL.0b013e3181fc2a06","article-title":"Retrospective analysis of NMDA receptor antibodies in encephalitis of unknown origin","volume":"2010","author":"Pr\u00fcss","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0410","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1093\/ageing\/afu098","article-title":"Anti-NMDA receptor encephalitis: An easily missed diagnosis in older patients","volume":"43","author":"Rainey","year":"2014","journal-title":"Age and Ageing"},{"key":"10.1016\/bs.apha.2017.08.005_bb0415","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1016\/j.jocn.2012.10.023","article-title":"Long duration between presentation of probable anti-N-methyl-d-aspartate receptor encephalitis and either clinical relapse or positive serum autoantibodies","volume":"20","author":"Ramanathan","year":"2013","journal-title":"Journal of Clinical Neuroscience"},{"key":"10.1016\/bs.apha.2017.08.005_bb0420","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.clineuro.2017.02.016","article-title":"Anti-NMDAR encephalitis followed by seropositive neuromyelitis optica spectrum disorder: A case report and literature review","volume":"155","author":"Ran","year":"2017","journal-title":"Clinical Neurology and Neurosurgery"},{"key":"10.1016\/bs.apha.2017.08.005_bb0425","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.sbi.2015.07.012","article-title":"A structural biology perspective on NMDA receptor pharmacology and function","volume":"33","author":"Regan","year":"2015","journal-title":"Current Opinion in Structural Biology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0430","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1007\/s11940-011-0116-y","article-title":"Anti-NMDA-receptor encephalitis and other synaptic autoimmune disorders","volume":"13","author":"Rosenfeld","year":"2011","journal-title":"Current Treatment Options in Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0435","doi-asserted-by":"crossref","first-page":"9367","DOI":"10.1523\/JNEUROSCI.23-28-09367.2003","article-title":"Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit","volume":"23","author":"Sans","year":"2003","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/bs.apha.2017.08.005_bb0440","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1093\/ijnp\/pyv102","article-title":"Cycloserine in neuropsychiatric diseases: A systematic review","volume":"19","author":"Schade","year":"2016","journal-title":"The International Journal of Neuropsychopharmacology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0445","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1212\/WNL.0000000000003536","article-title":"Bortezomib for treatment of therapy-refractory anti-NMDA receptor encephalitis","volume":"88","author":"Scheibe","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0450","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jcv.2016.08.292","article-title":"Anti-NMDA receptor antibody encephalitis with concomitant detection of Varicella zoster virus","volume":"83","author":"Sol\u00eds","year":"2016","journal-title":"Journal of Clinical Virology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0455","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1212\/WNL.0000000000003713","article-title":"Investigations in GABA(A) receptor antibody-associated encephalitis","volume":"88","author":"Spatola","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0460","doi-asserted-by":"crossref","first-page":"e145","DOI":"10.1111\/j.1468-1331.2011.03485.x","article-title":"A case of anti-N-methyl-d-aspartate receptor encephalitis with systemic sclerosis","volume":"18","author":"Suzuki","year":"2011","journal-title":"European Journal of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0465","first-page":"1566","article-title":"Anti-N-methyl-d-aspartate receptor encephalitis: A patient with refractory illness after 25 months of intensive immunotherapy","volume":"70","author":"Thomas","year":"2013","journal-title":"JAMA Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0470","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/ana.24117","article-title":"Overlapping demyelinating syndromes and anti-N-methyl-d-aspartate receptor encephalitis","volume":"75","author":"Titulaer","year":"2014","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0475","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S1474-4422(12)70310-1","article-title":"Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: An observational cohort study","volume":"12","author":"Titulaer","year":"2013","journal-title":"Lancet Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0480","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1212\/WNL.0b013e3182a4a49c","article-title":"Late-onset anti-NMDA receptor encephalitis","volume":"81","author":"Titulaer","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0485","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1124\/pr.109.002451","article-title":"Glutamate receptor ion channels: Structure, regulation, and function","volume":"62","author":"Traynelis","year":"2010","journal-title":"Pharmacological Reviews"},{"key":"10.1016\/bs.apha.2017.08.005_bb0490","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1471-244X-12-37","article-title":"Anti-NMDA-receptor antibody detected in encephalitis, schizophrenia, and narcolepsy with psychotic features","volume":"12","author":"Tsutsui","year":"2012","journal-title":"BMC Psychiatry"},{"issue":"4","key":"10.1016\/bs.apha.2017.08.005_bb0495","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.clineuro.2011.10.047","article-title":"Anti-N-methyl d-aspartate-type glutamate receptor antibody-positive limbic encephalitis in a patient with multiple sclerosis","volume":"114","author":"Uzawa","year":"2012","journal-title":"Clinical Neurology and Neurosurgery"},{"key":"10.1016\/bs.apha.2017.08.005_bb0500","first-page":"2011","article-title":"Appearance of anti-NMDAR antibodies after plasma exchange and total removal of malignant ovarian teratoma in a patient with paraneoplastic limbic encephalopathy","volume":"2011","author":"Wali","year":"2011","journal-title":"BML Case Reports"},{"key":"10.1016\/bs.apha.2017.08.005_bb0505","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1523\/JNEUROSCI.16-06-01982.1996","article-title":"Evidence for multiple AMPA receptor complexes in hippocampal CA1\/CA2 neurons","volume":"16","author":"Wenthold","year":"1996","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/bs.apha.2017.08.005_bb0510","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1007\/s10072-016-2563-4","article-title":"Anti-N-methyl-d-aspartate receptor encephalitis with lung adenocarcinoma","volume":"37","author":"Wu","year":"2016","journal-title":"Neurological Sciences"},{"key":"10.1016\/bs.apha.2017.08.005_bb0515","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1007\/s00415-015-7781-9","article-title":"Treatment and outcome of children and adolescents with N-methyl-d-aspartate receptor encephalitis","volume":"262","author":"Zekeridou","year":"2015","journal-title":"Journal of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0520","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.coph.2014.10.009","article-title":"Allosteric modulators of NMDA receptors: Multiple sites and mechanisms","volume":"20","author":"Zhu","year":"2015","journal-title":"Current Opinion in Pharmacology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0525","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.1007\/s00415-013-7182-x","article-title":"Aquaporin-4 antibody neuromyelitis optica following anti-NMDA receptor encephalitis","volume":"260","author":"Zoccarato","year":"2013","journal-title":"Journal of Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0530","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1212\/WNL.0000000000001072","article-title":"VZV brainstem encephalitis triggers NMDA receptor immunoreaction","volume":"83","author":"Sch\u00e4bitz","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/bs.apha.2017.08.005_bb0535","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.brainres.2015.12.027","article-title":"Stereotactic injection of cerebrospinal fluid from anti-NMDA receptor encephalitis into rat dentate gyrus impairs NMDA receptor function","volume":"1633","author":"W\u00fcrdemann","year":"2016","journal-title":"Brain Research"}],"container-title":["Advances in Pharmacology","Apprentices to Genius: A tribute to Solomon H. Snyder"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054358917300704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054358917300704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,26]],"date-time":"2018-08-26T05:39:21Z","timestamp":1535261961000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1054358917300704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9780128140871"],"references-count":112,"URL":"https:\/\/doi.org\/10.1016\/bs.apha.2017.08.005","relation":{},"ISSN":["1054-3589"],"issn-type":[{"value":"1054-3589","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}