{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T21:08:49Z","timestamp":1775941729015,"version":"3.50.1"},"reference-count":137,"publisher":"Elsevier","isbn-type":[{"value":"9780128166680","type":"print"}],"license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.1016\/bs.apha.2019.04.003","type":"book-chapter","created":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T11:50:57Z","timestamp":1556797857000},"page":"237-271","source":"Crossref","is-referenced-by-count":14,"title":["Obsessive compulsive disorder (OCD): Current treatments and a framework for neurotherapeutic research"],"prefix":"10.1016","author":[{"given":"Erik Z.","family":"Woody","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt Leroy","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry","family":"Szechtman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.beth.2017.06.002","article-title":"Presidential address: Are the obsessive-compulsive related disorders related to obsessive-compulsive disorder? A critical look at DSM-5's new category","volume":"49","author":"Abramowitz","year":"2018","journal-title":"Behavior Therapy"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0015","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.janxdis.2006.05.003","article-title":"The cognitive mediation of obsessive-compulsive symptoms: A longitudinal study","volume":"21","author":"Abramowitz","year":"2007","journal-title":"Journal of Anxiety Disorders"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0020","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1017\/S0140525X00061926","article-title":"Brain mechanisms for offense, defense, and submission","volume":"2","author":"Adams","year":"1979","journal-title":"The Behavioral and Brain Sciences"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0025","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.pharmthera.2006.08.004","article-title":"Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission","volume":"113","author":"Alex","year":"2007","journal-title":"Pharmacology and Therapeutics"},{"key":"10.1016\/bs.apha.2019.04.003_bb9000","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1146\/annurev.ne.09.030186.002041","article-title":"Parallel organization of functionally segregated circuits linking basal ganglia and cortex","volume":"9","author":"Alexander","year":"1986","journal-title":"Annual Review of Neuroscience"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0030","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/FBP.0b013e32835d5b7a","article-title":"Quinpirole and 8-OH-DPAT induce compulsive checking behavior in male rats by acting on different functional parts of an OCD neurocircuit","volume":"24","author":"Alkhatib","year":"2013","journal-title":"Behavioural Pharmacology"},{"key":"10.1016\/bs.apha.2019.04.003_bb0035","series-title":"Diagnostic and statistical manual of mental disorders (DSM-5\u00ae)","author":"American Psychiatric Association","year":"2013"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0040","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1177\/070674378603100314","article-title":"Clomipramine: An antiobsessive drug","volume":"31","author":"Ananth","year":"1986","journal-title":"Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie"},{"issue":"5","key":"10.1016\/bs.apha.2019.04.003_bb0045","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0361-9230(01)00614-1","article-title":"Modern views on an ancient chemical: Serotonin effects on cell proliferation, maturation, and apoptosis","volume":"56","author":"Azmitia","year":"2001","journal-title":"Brain Research Bulletin"},{"issue":"8","key":"10.1016\/bs.apha.2019.04.003_bb0050","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1136\/jnnp-2017-317082","article-title":"Charting the road forward in psychiatric neurosurgery: Proceedings of the 2016 American Society for stereotactic and functional neurosurgery workshop on neuromodulation for psychiatric disorders","volume":"89","author":"Bari","year":"2018","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jocn.2009.02.043","article-title":"Neurosurgery for obsessive-compulsive disorder: Contemporary approaches","volume":"17","author":"Bear","year":"2010","journal-title":"Journal of Clinical Neuroscience"},{"issue":"6","key":"10.1016\/bs.apha.2019.04.003_bb0060","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.conb.2003.11.001","article-title":"Deep brain stimulation for Parkinson's disease","volume":"13","author":"Benabid","year":"2003","journal-title":"Current Opinion in Neurobiology"},{"issue":"Pt 10","key":"10.1016\/bs.apha.2019.04.003_bb0065","doi-asserted-by":"crossref","first-page":"3061","DOI":"10.1093\/brain\/awv228","article-title":"Network localization of neurological symptoms from focal brain lesions","volume":"138","author":"Boes","year":"2015","journal-title":"Brain"},{"key":"10.1016\/bs.apha.2019.04.003_bb0070","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.neuroscience.2015.05.055","article-title":"Using human brain imaging studies as a guide toward animal models of schizophrenia","volume":"321","author":"Bolkan","year":"2016","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0075","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1017\/S0140525X0000491X","article-title":"A perceptual-defensive-recuperative model of fear and pain","volume":"3","author":"Bolles","year":"1980","journal-title":"The Behavioral and Brain Sciences"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0080","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1159\/000149583","article-title":"The contributions of Paul Ehrlich to pharmacology: A tribute on the occasion of the centenary of his nobel prize","volume":"82","author":"Bosch","year":"2008","journal-title":"Pharmacology"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0085","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3390\/brainsci8020037","article-title":"Transcranial direct current stimulation for obsessive-compulsive disorder: A systematic review","volume":"8","author":"Brunelin","year":"2018","journal-title":"Brain Sciences"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0090","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.brs.2017.09.004","article-title":"Clinical and electrophysiological outcomes of deep TMS over the medial prefrontal and anterior cingulate cortices in OCD patients","volume":"11","author":"Carmi","year":"2018","journal-title":"Brain Stimulation"},{"issue":"11","key":"10.1016\/bs.apha.2019.04.003_bb0095","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1038\/nrn3621","article-title":"DSM-5 and RDoC: Progress in psychiatry research?","volume":"14","author":"Casey","year":"2013","journal-title":"Nature Reviews. Neuroscience"},{"issue":"4","key":"10.1016\/bs.apha.2019.04.003_bb0100","doi-asserted-by":"crossref","first-page":"471","DOI":"10.31887\/DCNS.2010.12.4\/ycharnay","article-title":"Brain serotonergic circuitries","volume":"12","author":"Charnay","year":"2010","journal-title":"Dialogues in Clinical Neuroscience"},{"issue":"8","key":"10.1016\/bs.apha.2019.04.003_bb0105","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1001\/archpsyc.1991.01810320054008","article-title":"Clomipramine in the treatment of patients with obsessive-compulsive disorder. The clomipramine collaborative study group","volume":"48","year":"1991","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/bs.apha.2019.04.003_bb9005","first-page":"119","article-title":"Monochlorimipramine in psychiatric patients resistant to other forms of treatment","volume":"26","author":"Cordoba Fernandez","year":"1967","journal-title":"Acta Luso-Espanolas Neurologia y Psiquiatrica"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0110","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/wps.20087","article-title":"The RDoC framework: Facilitating transition from ICD\/DSM to dimensional approaches that integrate neuroscience and psychopathology","volume":"13","author":"Cuthbert","year":"2014","journal-title":"World Psychiatry"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0115","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/brain\/aww288","article-title":"Finding the imposter: Brain connectivity of lesions causing delusional misidentifications","volume":"140","author":"Darby","year":"2017","journal-title":"Brain"},{"issue":"11","key":"10.1016\/bs.apha.2019.04.003_bb0120","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1111\/ejn.12607","article-title":"Modelling the genetic contribution to mental illness: A timely end for the psychiatric rodent?","volume":"39","author":"Davis","year":"2014","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/bs.apha.2019.04.003_bb0125","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.eurpsy.2016.06.011","article-title":"D-Cycloserine addition to exposure sessions in the treatment of patients with obsessive-compulsive disorder","volume":"40","author":"de Leeuw","year":"2017","journal-title":"European Psychiatry"},{"issue":"10","key":"10.1016\/bs.apha.2019.04.003_bb0130","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/archgenpsychiatry.2010.122","article-title":"Deep brain stimulation of the nucleus accumbens for treatment-refractory obsessive-compulsive disorder","volume":"67","author":"Denys","year":"2010","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/bs.apha.2019.04.003_bb0135","series-title":"Serotonin-dopamine interaction: Experimental evidence and therapeutic relevance","first-page":"45","article-title":"Serotonin-dopamine interaction: Electrophysiological evidence","volume":"Vol. 172","author":"Di Giovanni","year":"2008"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0140","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2466\/pr0.1992.70.1.35","article-title":"Unusual cleaning behavior in the luteal phase","volume":"70","author":"Dillon","year":"1992","journal-title":"Psychological Reports"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0145","doi-asserted-by":"crossref","first-page":"125","DOI":"10.2307\/4444260","article-title":"Nothing in biology makes sense except in the light of evolution","volume":"35","author":"Dobzhansky","year":"1973","journal-title":"The American Biology Teacher"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0150","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1017\/S1461145712000740","article-title":"Antipsychotic augmentation of serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder: A meta-analysis of double-blind, randomized, placebo-controlled trials","volume":"16","author":"Dold","year":"2013","journal-title":"International Journal of Neuropsychopharmacology"},{"issue":"9","key":"10.1016\/bs.apha.2019.04.003_bb0155","doi-asserted-by":"crossref","DOI":"10.1093\/ijnp\/pyv047","article-title":"Antipsychotic augmentation of serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder: An update meta-analysis of double-blind, randomized, placebo-controlled trials","volume":"18","author":"Dold","year":"2015","journal-title":"International Journal of Neuropsychopharmacology"},{"issue":"5","key":"10.1016\/bs.apha.2019.04.003_bb0160","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0005-7967(77)90050-X","article-title":"Obsessional ruminations: A comparison between thought-stopping and prolonged exposure in imagination","volume":"15","author":"Emmelkamp","year":"1977","journal-title":"Behaviour Research and Therapy"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0165","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s10522-012-9406-3","article-title":"Serotonin: From top to bottom","volume":"14","author":"Fidalgo","year":"2013","journal-title":"Biogerontology"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0170","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.psychres.2014.12.003","article-title":"Obsessive-compulsive disorder (OCD): Practical strategies for pharmacological and somatic treatment in adults","volume":"227","author":"Fineberg","year":"2015","journal-title":"Psychiatry Research"},{"issue":"4","key":"10.1016\/bs.apha.2019.04.003_bb0175","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/00005053-199704000-00001","article-title":"Is obsessive-compulsive disorder a pathology of the human disposition to perform socially meaningful rituals? Evidence of similar content","volume":"185","author":"Fiske","year":"1997","journal-title":"Journal of Nervous and Mental Disease"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0180","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.yhbeh.2010.11.014","article-title":"Progesterone's effects on the psychology of disease avoidance: Support for the compensatory behavioral prophylaxis hypothesis","volume":"59","author":"Fleischman","year":"2011","journal-title":"Hormones and Behavior"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0185","doi-asserted-by":"crossref","first-page":"199","DOI":"10.31887\/DCNS.2010.12.2\/efoa","article-title":"Cognitive behavioral therapy of obsessive-compulsive disorder","volume":"12","author":"Foa","year":"2010","journal-title":"Dialogues in Clinical Neuroscience"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0190","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1176\/appi.ajp.162.1.151","article-title":"Randomized, placebo-controlled trial of exposure and ritual prevention, clomipramine, and their combination in the treatment of obsessive-compulsive disorder","volume":"162","author":"Foa","year":"2005","journal-title":"American Journal of Psychiatry"},{"issue":"5","key":"10.1016\/bs.apha.2019.04.003_bb0195","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0005-7894(84)80049-0","article-title":"Deliberate exposure and blocking of obsessive-compulsive rituals: Immediate and long-term effects","volume":"15","author":"Foa","year":"1984","journal-title":"Behavior Therapy"},{"key":"10.1016\/bs.apha.2019.04.003_bb0200","series-title":"Human nature and suffering","author":"Gilbert","year":"1989"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0205","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.psc.2014.06.004","article-title":"Obsessive-compulsive disorder","volume":"37","author":"Goodman","year":"2014","journal-title":"Psychiatric Clinics of North America"},{"issue":"11","key":"10.1016\/bs.apha.2019.04.003_bb0210","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1001\/archpsyc.1989.01810110054008","article-title":"The yale-brown obsessive compulsive scale. II. Validity","volume":"46","author":"Goodman","year":"1989","journal-title":"Archives of General Psychiatry"},{"issue":"11","key":"10.1016\/bs.apha.2019.04.003_bb0215","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1001\/archpsyc.1989.01810110048007","article-title":"The yale-brown obsessive compulsive scale. I. Development, use, and reliability","volume":"46","author":"Goodman","year":"1989","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/bs.apha.2019.04.003_bb0220","series-title":"The breakthrough: Immunotherapy and the race to cure cancer","author":"Graeber","year":"2018"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0225","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/mp.2008.55","article-title":"Deep brain stimulation of the ventral internal capsule\/ventral striatum for obsessive-compulsive disorder: Worldwide experience","volume":"15","author":"Greenberg","year":"2010","journal-title":"Molecular Psychiatry"},{"issue":"12","key":"10.1016\/bs.apha.2019.04.003_bb0230","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1002\/da.22234","article-title":"Obsessive-compulsive disorder and female reproductive cycle events: Results from the OCD and reproduction collaborative study","volume":"31","author":"Guglielmi","year":"2014","journal-title":"Depression and Anxiety"},{"issue":"5","key":"10.1016\/bs.apha.2019.04.003_bb0235","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1021\/ci5000533","article-title":"Setting the record straight: The origin of the pharmacophore concept","volume":"54","author":"Guner","year":"2014","journal-title":"Journal of Chemical Information and Modeling"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0240","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.neuron.2007.06.026","article-title":"Transcranial magnetic stimulation: A primer","volume":"55","author":"Hallett","year":"2007","journal-title":"Neuron"},{"issue":"639","key":"10.1016\/bs.apha.2019.04.003_bb0245","doi-asserted-by":"crossref","first-page":"639","DOI":"10.3389\/fpsyg.2018.00639","article-title":"The Bergen 4-day OCD treatment delivered in a group setting: 12-month follow-up","volume":"9","author":"Hansen","year":"2018","journal-title":"Frontiers in Psychology"},{"key":"10.1016\/bs.apha.2019.04.003_bb0250","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3389\/fpsyt.2017.00101","article-title":"Why psychiatric research must abandon traditional diagnostic classification and adopt a fully dimensional scope: Two solutions to a persistent problem","volume":"8","author":"Hengartner","year":"2017","journal-title":"Frontiers in Psychiatry"},{"issue":"Pt B","key":"10.1016\/bs.apha.2019.04.003_bb0255","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jbtep.2015.03.016","article-title":"In the wake of a possible mistake: Security motivation, checking behavior, and OCD","volume":"49","author":"Hinds","year":"2015","journal-title":"Journal of Behavior Therapy and Experimental Psychiatry"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0260","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030586","article-title":"When too much is not enough: Obsessive-compulsive disorder as a pathology of stopping, rather than starting","volume":"7","author":"Hinds","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/bs.apha.2019.04.003_bb0265","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev.clinpsy.3.022806.091532","article-title":"The diagnosis of mental disorders: The problem of reification","volume":"6","author":"Hyman","year":"2010","journal-title":"Annual Review of Clinical Psychology"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0270","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1152\/physrev.1992.72.1.165","article-title":"Structure and function of the brain serotonin system","volume":"72","author":"Jacobs","year":"1992","journal-title":"Physiological Reviews"},{"key":"10.1016\/bs.apha.2019.04.003_bb0275","series-title":"Psychopharmacology: The fourth generation of progress","first-page":"461","article-title":"Serotonin and behavior: A general hypothesis","author":"Jacobs","year":"1995"},{"key":"10.1016\/bs.apha.2019.04.003_bb0280","series-title":"General psychopathology","author":"Jaspers","year":"1963"},{"issue":"5","key":"10.1016\/bs.apha.2019.04.003_bb0285","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1097\/FBP.0000000000000219","article-title":"A dose-response study of separate and combined effects of the serotonin agonist 8-OH-DPAT and the dopamine agonist quinpirole on locomotor sensitization, cross-sensitization, and conditioned activity","volume":"27","author":"Johnson","year":"2016","journal-title":"Behavioural Pharmacology"},{"key":"10.1016\/bs.apha.2019.04.003_bb0290","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jocrd.2015.04.004","article-title":"Intensive cognitive behavioural therapy for obsessive-compulsive disorder: A systematic review and meta-analysis","volume":"6","author":"Jonsson","year":"2015","journal-title":"Journal of Obsessive-Compulsive and Related Disorders"},{"issue":"4","key":"10.1016\/bs.apha.2019.04.003_bb0295","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1176\/ajp.153.4.466","article-title":"Serotonin-dopamine interaction and its relevance to schizophrenia","volume":"153","author":"Kapur","year":"1996","journal-title":"American Journal of Psychiatry"},{"issue":"Suppl 1","key":"10.1016\/bs.apha.2019.04.003_bb0300","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1186\/1471-244X-14-S1-S1","article-title":"Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders","volume":"14","author":"Katzman","year":"2014","journal-title":"BMC Psychiatry"},{"issue":"6","key":"10.1016\/bs.apha.2019.04.003_bb0305","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1176\/appi.ajp.2008.07071061","article-title":"Explanatory models for psychiatric illness","volume":"165","author":"Kendler","year":"2008","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/bs.apha.2019.04.003_bb0310","series-title":"Guideline watch (2013): Practice guideline for the treatment of patients with obsessive-compulsive disorder","author":"Koran","year":"2013"},{"key":"10.1016\/bs.apha.2019.04.003_bb0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0447.1999.tb10951.x","article-title":"Early parental preoccupations and behaviors and their possible relationship to the symptoms of obsessive-compulsive disorder","volume":"396","author":"Leckman","year":"1999","journal-title":"Acta Psychiatrica Scandinavica. Supplementum"},{"issue":"11","key":"10.1016\/bs.apha.2019.04.003_bb0320","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.clinph.2014.05.021","article-title":"Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)","volume":"125","author":"Lefaucheur","year":"2014","journal-title":"Clinical Neurophysiology"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0325","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.clinph.2016.10.087","article-title":"Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)","volume":"128","author":"Lefaucheur","year":"2017","journal-title":"Clinical Neurophysiology"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0330","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/s41398-018-0128-4","article-title":"Brain serotonin synthesis capacity in obsessive-compulsive disorder: Effects of cognitive behavioral therapy and sertraline","volume":"8","author":"Lissemore","year":"2018","journal-title":"Translational Psychiatry"},{"issue":"9","key":"10.1016\/bs.apha.2019.04.003_bb0335","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1038\/mp.2015.124","article-title":"Electrical stimulation in the bed nucleus of the stria terminalis alleviates severe obsessive-compulsive disorder","volume":"21","author":"Luyten","year":"2016","journal-title":"Molecular Psychiatry"},{"issue":"20","key":"10.1016\/bs.apha.2019.04.003_bb0340","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1056\/NEJMoa0708514","article-title":"Subthalamic nucleus stimulation in severe obsessive-compulsive disorder","volume":"359","author":"Mallet","year":"2008","journal-title":"New England Journal of Medicine"},{"issue":"5\u20136","key":"10.1016\/bs.apha.2019.04.003_bb0345","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0162-3095(94)90002-7","article-title":"Fear and fitness: An evolutionary analysis of anxiety disorders","volume":"15","author":"Marks","year":"1994","journal-title":"Ethology and Sociobiology"},{"issue":"4","key":"10.1016\/bs.apha.2019.04.003_bb0350","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1017\/S0140525X00014114","article-title":"The defense motivation system\u2014A theory of avoidance-behavior","volume":"5","author":"Masterson","year":"1982","journal-title":"Behavioral and Brain Sciences"},{"issue":"5","key":"10.1016\/bs.apha.2019.04.003_bb0355","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1001\/jamapsychiatry.2016.3955","article-title":"D-Cycloserine augmentation of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders: A systematic review and meta-analysis of individual participant data","volume":"74","author":"Mataix-Cols","year":"2017","journal-title":"JAMA Psychiatry"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0360","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4088\/JCP.15r10334","article-title":"A meta-analysis of D-Cycloserine in exposure-based treatment: Moderators of treatment efficacy, response, and diagnostic remission","volume":"78","author":"McGuire","year":"2017","journal-title":"Journal of Clinical Psychiatry"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0365","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.psychres.2015.02.004","article-title":"Efficacy of cognitive-behavioral therapy for obsessive-compulsive disorder","volume":"227","author":"McKay","year":"2015","journal-title":"Psychiatry Research"},{"issue":"8","key":"10.1016\/bs.apha.2019.04.003_bb0370","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.parkreldis.2007.07.020","article-title":"Basal ganglia physiology and pathophysiology: A reappraisal","volume":"13","author":"Montgomery","year":"2007","journal-title":"Parkinsonism & Related Disorders"},{"key":"10.1016\/bs.apha.2019.04.003_bb0375","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3389\/fnint.2012.00078","article-title":"The epistemology of deep brain stimulation and neuronal pathophysiology","volume":"6","author":"Montgomery","year":"2012","journal-title":"Frontiers in Integrative Neuroscience"},{"key":"10.1016\/bs.apha.2019.04.003_bb0380","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3389\/fnhum.2016.00469","article-title":"Modeling and theories of pathophysiology and physiology of the basal ganglia-thalamic-cortical system: Critical analysis","volume":"10","author":"Montgomery","year":"2016","journal-title":"Frontiers in Human Neuroscience"},{"key":"10.1016\/bs.apha.2019.04.003_bb0385","series-title":"Deep brain stimulation programming: Mechanisms, principles, and practice","author":"Montgomery","year":"2017"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0390","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.neubiorev.2007.06.003","article-title":"Mechanisms of action of deep brain stimulation (DBS)","volume":"32","author":"Montgomery","year":"2008","journal-title":"Neuroscience and Biobehavioral Reviews"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0395","doi-asserted-by":"crossref","first-page":"E34","DOI":"10.3390\/brainsci6030034","article-title":"Deep brain stimulation frequency\u2014A divining rod for new and novel concepts of nervous system function and therapy","volume":"6","author":"Montgomery","year":"2016","journal-title":"Brain Sciences"},{"key":"10.1016\/bs.apha.2019.04.003_bb0400","series-title":"In obsessive-compulsive disorder: Core interventions in the treatment of obsessive-compulsive disorder and body dysmorphic disorder","article-title":"National Institute for health and clinical excellence: Guidance","year":"2006"},{"issue":"10","key":"10.1016\/bs.apha.2019.04.003_bb0405","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/nn.2647","article-title":"Animal models of neuropsychiatric disorders","volume":"13","author":"Nestler","year":"2010","journal-title":"Nature Neuroscience"},{"key":"10.1016\/bs.apha.2019.04.003_bb0410","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.wneu.2016.10.008","article-title":"Surgical approaches in psychiatry: A survey of the world literature on psychosurgery","volume":"97","author":"Neumaier","year":"2017","journal-title":"World Neurosurgery"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0415","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jpsychires.2012.08.020","article-title":"Cognitive-behavioral therapy for obsessive-compulsive disorder: A meta-analysis of treatment outcome and moderators","volume":"47","author":"Olatunji","year":"2013","journal-title":"Journal of Psychiatric Research"},{"key":"10.1016\/bs.apha.2019.04.003_bb0420","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.cpr.2015.06.003","article-title":"Cognitive behavioral treatments of obsessive-compulsive disorder. A systematic review and meta-analysis of studies published 1993\u20132014","volume":"40","author":"Ost","year":"2015","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/bs.apha.2019.04.003_bb0425","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/1471-244X-11-200","article-title":"Efficacy of exposure versus cognitive therapy in anxiety disorders: Systematic review and meta-analysis","volume":"11","author":"Ougrin","year":"2011","journal-title":"BMC Psychiatry"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0430","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0165-0173(94)00007-C","article-title":"Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop","volume":"20","author":"Parent","year":"1995","journal-title":"Brain Research: Brain Research Reviews"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0435","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0165-0173(94)00008-D","article-title":"Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidum in basal ganglia circuitry","volume":"20","author":"Parent","year":"1995","journal-title":"Brain Research: Brain Research Reviews"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0440","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1037\/gpr0000004","article-title":"The asymmetric behavioral homeostasis hypothesis: Unidirectional flexibility of fundamental motivational processes","volume":"18","author":"Park","year":"2014","journal-title":"Review of General Psychology"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0445","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1146\/annurev.neuro.27.070203.144216","article-title":"The plastic human brain cortex","volume":"28","author":"Pascual-Leone","year":"2005","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/bs.apha.2019.04.003_bb0450","series-title":"Brain arousal and information theory: Neural and genetic mechanisms","author":"Pfaff","year":"2006"},{"key":"10.1016\/bs.apha.2019.04.003_bb0455","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1747-5341-7-9","article-title":"The six most essential questions in psychiatric diagnosis: A pluralogue part 3: Issues of utility and alternative approaches in psychiatric diagnosis","volume":"7","author":"Phillips","year":"2012","journal-title":"Philosophy, Ethics, and Humanities in Medicine"},{"issue":"1 Suppl 1","key":"10.1016\/bs.apha.2019.04.003_bb0460","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1365-2125.1976.tb03721.x","article-title":"The assessment of drugs in obsessional states","volume":"3","author":"Philpott","year":"1976","journal-title":"British Journal of Clinical Pharmacology"},{"issue":"4","key":"10.1016\/bs.apha.2019.04.003_bb0465","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1192\/bjp.166.4.424","article-title":"Efficacy of drug treatment in obsessive-compulsive disorder. A meta-analytic review","volume":"166","author":"Piccinelli","year":"1995","journal-title":"British Journal of Psychiatry"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0470","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.psc.2014.05.006","article-title":"Pharmacological treatment of obsessive-compulsive disorder","volume":"37","author":"Pittenger","year":"2014","journal-title":"Psychiatric Clinics of North America"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0475","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/scientificamerican0389-82","article-title":"The biology of obsessions and compulsions","volume":"260","author":"Rapoport","year":"1989","journal-title":"Scientific American"},{"key":"10.1016\/bs.apha.2019.04.003_bb0480","series-title":"Obsessional experience and compulsive behaviour: A cognitive-structural approach","author":"Reed","year":"1985"},{"issue":"8","key":"10.1016\/bs.apha.2019.04.003_bb0485","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1016\/j.cpr.2008.07.001","article-title":"Psychological treatment of obsessive-compulsive disorder: A meta-analysis","volume":"28","author":"Rosa-Alcazar","year":"2008","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/bs.apha.2019.04.003_bb0490","doi-asserted-by":"crossref","first-page":"E20","DOI":"10.1017\/sjp.2015.22","article-title":"Psychological treatment of obsessive-compulsive disorder in children and adolescents: A meta-analysis","volume":"18","author":"Rosa-Alcazar","year":"2015","journal-title":"Spanish Journal of Psychology"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0495","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0005-7967(89)90073-9","article-title":"Behaviour therapy and obsessional ruminations: Can failure be turned into success?","volume":"27","author":"Salkovskis","year":"1989","journal-title":"Behaviour Research and Therapy"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0500","first-page":"229","article-title":"Brain dopamine receptors","volume":"32","author":"Seeman","year":"1980","journal-title":"Pharmacological Reviews"},{"issue":"4","key":"10.1016\/bs.apha.2019.04.003_bb0505","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1586\/17434440.2015.1037832","article-title":"Transcranial direct current stimulation in obsessive-compulsive disorder: Emerging clinical evidence and considerations for optimal montage of electrodes","volume":"12","author":"Senco","year":"2015","journal-title":"Expert Review of Medical Devices"},{"issue":"Pt B","key":"10.1016\/bs.apha.2019.04.003_bb0510","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.neuroimage.2017.08.010","article-title":"Principles of dynamic network reconfiguration across diverse brain states","volume":"180","author":"Shine","year":"2018","journal-title":"Neuroimage"},{"issue":"5","key":"10.1016\/bs.apha.2019.04.003_bb0515","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1176\/appi.ajp.2007.07091440","article-title":"A randomized, controlled trial of cognitive-behavioral therapy for augmenting pharmacotherapy in obsessive-compulsive disorder","volume":"165","author":"Simpson","year":"2008","journal-title":"American Journal of Psychiatry"},{"issue":"43","key":"10.1016\/bs.apha.2019.04.003_bb0520","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta20430","article-title":"A systematic review of the clinical effectiveness and cost-effectiveness of pharmacological and psychological interventions for the management of obsessive-compulsive disorder in children\/adolescents and adults","volume":"20","author":"Skapinakis","year":"2016","journal-title":"Health Technology Assessment"},{"issue":"8","key":"10.1016\/bs.apha.2019.04.003_bb0525","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/S2215-0366(16)30069-4","article-title":"Pharmacological and psychotherapeutic interventions for management of obsessive-compulsive disorder in adults: A systematic review and network meta-analysis","volume":"3","author":"Skapinakis","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0530","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.euroneuro.2006.07.002","article-title":"Antipsychotic augmentation of serotonergic antidepressants in treatment-resistant obsessive-compulsive disorder: A meta-analysis of the randomized controlled trials","volume":"17","author":"Skapinakis","year":"2007","journal-title":"European Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0535","article-title":"Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD)","author":"Soomro","year":"2008","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1016\/bs.apha.2019.04.003_bb0540","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1017\/S0140525X00022871","article-title":"Reconciling the role of central serotonin neurons in human and animal behavior","volume":"9","author":"Soubrie","year":"1986","journal-title":"The Behavioral and Brain Sciences"},{"key":"10.1016\/bs.apha.2019.04.003_bb0545","series-title":"Treatment of obsessive compulsive disorder","author":"Steketee","year":"1993"},{"key":"10.1016\/bs.apha.2019.04.003_bb0550","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1192\/bjp.133.3.200","article-title":"Obsessive thoughts: The problem of therapy","volume":"133","author":"Stern","year":"1978","journal-title":"British Journal of Psychiatry"},{"issue":"6","key":"10.1016\/bs.apha.2019.04.003_bb0555","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/nrc2394","article-title":"Paul Ehrlich's magic bullet concept: 100 years of progress","volume":"8","author":"Strebhardt","year":"2008","journal-title":"Nature Reviews. Cancer"},{"issue":"4","key":"10.1016\/bs.apha.2019.04.003_bb0560","doi-asserted-by":"crossref","first-page":"317","DOI":"10.2174\/1573400510666140619224942","article-title":"The future of D-Cycloserine and other cognitive modifiers in obsessive-compulsive and related disorders","volume":"10","author":"Sulkowski","year":"2014","journal-title":"Current Psychiatry Reviews"},{"key":"10.1016\/bs.apha.2019.04.003_bb0565","series-title":"The behavior of the laboratory rat: A handbook with tests","first-page":"462","article-title":"Psychiatric models","author":"Szechtman","year":"2005"},{"issue":"6","key":"10.1016\/bs.apha.2019.04.003_bb0570","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1037\/0735-7044.112.6.1475","article-title":"Quinpirole induces compulsive checking behavior in rats: A potential animal model of obsessive-compulsive disorder (OCD)","volume":"112","author":"Szechtman","year":"1998","journal-title":"Behavioral Neuroscience"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0575","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1037\/0033-295X.111.1.111","article-title":"Obsessive-compulsive disorder as a disturbance of security motivation","volume":"111","author":"Szechtman","year":"2004","journal-title":"Psychological Review"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0580","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1080\/1047840X.2017.1256132","article-title":"Adaptationism carves emotions at their functional joints","volume":"28","author":"Sznycer","year":"2017","journal-title":"Psychological Inquiry"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0585","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1037\/0033-295X.112.3.650","article-title":"Is obsessive-compulsive disorder a disturbance of security motivation? Comment on Szechtman and Woody (2004)","volume":"112","author":"Taylor","year":"2005","journal-title":"Psychological Review"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0590","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.bbr.2012.01.030","article-title":"Some useful insights for graduate students beginning their research in physiological psychology: Anecdotes and attitudes","volume":"231","author":"Teitelbaum","year":"2012","journal-title":"Behavioural Brain Research"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0595","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1467-9280.1992.tb00249.x","article-title":"Toward a synthetic physiological psychology","volume":"3","author":"Teitelbaum","year":"1992","journal-title":"Psychological Science"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0600","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.cbpra.2008.07.001","article-title":"Alphabet soup: ERP, CT, and ACT for OCD","volume":"16","author":"Tolin","year":"2009","journal-title":"Cognitive and Behavioral Practice"},{"key":"10.1016\/bs.apha.2019.04.003_bb0605","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0162-3095(90)90017-Z","article-title":"The past explains the present: Emotional adaptations and the structure of ancestral environments","volume":"11","author":"Tooby","year":"1990","journal-title":"Ethology and Sociobiology"},{"key":"10.1016\/bs.apha.2019.04.003_bb0610","series-title":"Handbook of approach and avoidance motivation","first-page":"251","article-title":"Internal regulatory variables and the design of human motivation: A computational and evolutionary approach","author":"Tooby","year":"2008"},{"issue":"6","key":"10.1016\/bs.apha.2019.04.003_bb0615","doi-asserted-by":"crossref","first-page":"2971","DOI":"10.1111\/ejn.12652","article-title":"Performance of compulsive behavior in rats is not a unitary phenomenon\u2014validation of separate functional components in compulsive checking behavior","volume":"40","author":"Tucci","year":"2014","journal-title":"European Journal of Neuroscience"},{"issue":"18","key":"10.1016\/bs.apha.2019.04.003_bb0620","doi-asserted-by":"crossref","first-page":"3707","DOI":"10.1007\/s00213-014-3505-6","article-title":"Separate mechanisms for development and performance of compulsive checking in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD)","volume":"231","author":"Tucci","year":"2014","journal-title":"Psychopharmacology"},{"key":"10.1016\/bs.apha.2019.04.003_bb0625","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1186\/s12888-014-0317-5","article-title":"Atypical antipsychotic augmentation in SSRI treatment refractory obsessive-compulsive disorder: A systematic review and meta-analysis","volume":"14","author":"Veale","year":"2014","journal-title":"BMC Psychiatry"},{"issue":"9","key":"10.1016\/bs.apha.2019.04.003_bb0630","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1158\/2159-8290.CD-18-0367","article-title":"Fundamental mechanisms of immune checkpoint blockade therapy","volume":"8","author":"Wei","year":"2018","journal-title":"Cancer Discovery"},{"key":"10.1016\/bs.apha.2019.04.003_bb0635","series-title":"Scale: The universal laws of growth, innovation, sustainability, and the pace of life in organisms, cities, economies, and companies","author":"West","year":"2017"},{"issue":"10","key":"10.1016\/bs.apha.2019.04.003_bb0640","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/S2215-0366(16)30280-2","article-title":"Network meta-analyses and treatment recommendations for obsessive-compulsive disorder","volume":"3","author":"Wheaton","year":"2016","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/bs.apha.2019.04.003_bb0645","series-title":"Wikipedia, the free encyclopedia","article-title":"Elixir of life","author":"Wikipedia contributors","year":"2018"},{"key":"10.1016\/bs.apha.2019.04.003_bb0650","series-title":"Obsessive compulsive disorder in children and adolescence","first-page":"327","article-title":"Obsessive compulsive disorder\u2014Is it a basal ganglia dysfunction?","author":"Wise","year":"1989"},{"key":"10.1016\/bs.apha.2019.04.003_bb0655","series-title":"Science, Technology & Society in the time of Alfred Nobel: Nobel symposium 52 held at Bj\u00f6rkborn, Karlskoga, Sweden, 17\u201322 August 1981","first-page":"146","article-title":"Paul Ehrlich: His ideas and his legacy","author":"Witkop","year":"1982"},{"issue":"3","key":"10.1016\/bs.apha.2019.04.003_bb0660","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1037\/0033-295X.112.3.658","article-title":"Motivation, time course, and heterogeneity in obsessive-compulsive disorder: Response to Taylor, McKay, and Abramowitz (2005)","volume":"112","author":"Woody","year":"2005","journal-title":"Psychological Review"},{"issue":"4","key":"10.1016\/bs.apha.2019.04.003_bb0665","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.neubiorev.2010.08.003","article-title":"Adaptation to potential threat: The evolution, neurobiology, and psychopathology of the security motivation system","volume":"35","author":"Woody","year":"2011","journal-title":"Neuroscience and Biobehavioral Reviews"},{"issue":"1","key":"10.1016\/bs.apha.2019.04.003_bb0670","first-page":"111","article-title":"The action of chlorimipramine in obsessive-compulsive neurosis: A pilot study","volume":"17","author":"Yaryura-Tobias","year":"1975","journal-title":"Current Therapeutic Research, Clinical and Experimental"},{"issue":"4, Pt 2","key":"10.1016\/bs.apha.2019.04.003_bb0675","first-page":"541","article-title":"Chlorimipramine, for obsessive-compulsive neurosis: An organic approach","volume":"20","author":"Yaryura-Tobias","year":"1976","journal-title":"Current Therapeutic Research"},{"issue":"2","key":"10.1016\/bs.apha.2019.04.003_bb0680","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.bbi.2010.10.015","article-title":"Immune modulation of learning, memory, neural plasticity and neurogenesis","volume":"25","author":"Yirmiya","year":"2011","journal-title":"Brain, Behavior, and Immunity"}],"container-title":["Advances in Pharmacology","Neuropsychotherapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054358919300201?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1054358919300201?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T22:12:52Z","timestamp":1607551972000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1054358919300201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"ISBN":["9780128166680"],"references-count":137,"URL":"https:\/\/doi.org\/10.1016\/bs.apha.2019.04.003","relation":{},"ISSN":["1054-3589"],"issn-type":[{"value":"1054-3589","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]}}}