{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:36:35Z","timestamp":1790775395596,"version":"4.1.0"},"reference-count":145,"publisher":"Elsevier","isbn-type":[{"value":"9780128092156","type":"print"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1016\/bs.ctdb.2017.08.005","type":"book-chapter","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T19:15:25Z","timestamp":1510341325000},"page":"99-124","source":"Crossref","is-referenced-by-count":53,"title":["The Composition, Development, and Regeneration of Neuromuscular Junctions"],"prefix":"10.1016","author":[{"given":"Wenxuan","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe V.","family":"Chakkalakal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/bs.ctdb.2017.08.005_bb0010","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1600-0838.2009.01084.x","article-title":"Role of the nervous system in sarcopenia and muscle atrophy with aging: Strength training as a countermeasure","volume":"20","author":"Aagaard","year":"2010","journal-title":"Scandinavian Journal of Medicine & Science in Sports"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0015","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S0896-6273(00)80303-7","article-title":"Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold","volume":"18","author":"Apel","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0020","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1523\/JNEUROSCI.13-02-00834.1993","article-title":"In vivo observations of pre- and postsynaptic changes during the transition from multiple to single innervation at developing neuromuscular junctions","volume":"13","author":"Balice-Gordon","year":"1993","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0025","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1113\/jphysiol.1983.sp014721","article-title":"Neuromuscular transmission and correlative morphology in young and old mice","volume":"339","author":"Banker","year":"1983","journal-title":"The Journal of Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0030","doi-asserted-by":"crossref","first-page":"9770","DOI":"10.1523\/JNEUROSCI.0174-16.2016","article-title":"Schwann cells in neuromuscular junction formation and maintenance","volume":"36","author":"Barik","year":"2016","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0035","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.biocel.2014.04.025","article-title":"Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice","volume":"53","author":"Barns","year":"2014","journal-title":"The International Journal of Biochemistry & Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0040","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1146\/annurev.biochem.75.103004.142622","article-title":"Signaling pathways in skeletal muscle remodeling","volume":"75","author":"Bassel-Duby","year":"2006","journal-title":"Annual Review of Biochemistry"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0045","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1523\/JNEUROSCI.4489-07.2008","article-title":"Retrograde signaling onto Ret during motor nerve terminal maturation","volume":"28","author":"Baudet","year":"2008","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0050","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a008342","article-title":"Building muscle: Molecular regulation of myogenesis","volume":"4","author":"Bentzinger","year":"2012","journal-title":"Cold Spring Harbor Perspectives in Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0055","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1152\/physrev.2000.80.3.1215","article-title":"Calcium ion in skeletal muscle: Its crucial role for muscle function, plasticity, and disease","volume":"80","author":"Berchtold","year":"2000","journal-title":"Physiological Reviews"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0060","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jaut.2014.01.003","article-title":"Diagnostic and clinical classification of autoimmune myasthenia gravis","volume":"48\u201349","author":"Berrih-Aknin","year":"2014","journal-title":"Journal of Autoimmunity"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0065","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1126\/science.1065874","article-title":"Identification of ubiquitin ligases required for skeletal muscle atrophy","volume":"294","author":"Bodine","year":"2001","journal-title":"Science"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0070","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3389\/fnana.2016.00006","article-title":"Neuromuscular junctions as key contributors and therapeutic targets in spinal muscular atrophy","volume":"10","author":"Boido","year":"2016","journal-title":"Frontiers in Neuroanatomy"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0075","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1242\/dmm.010389","article-title":"Cellular and molecular mechanisms of muscle atrophy","volume":"6","author":"Bonaldo","year":"2013","journal-title":"Disease Models & Mechanisms"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0080","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a001735","article-title":"Motor axon pathfinding","volume":"2","author":"Bonanomi","year":"2010","journal-title":"Cold Spring Harbor Perspectives in Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0085","doi-asserted-by":"crossref","first-page":"356","DOI":"10.3389\/fphys.2013.00356","article-title":"More than a bystander: The contributions of intrinsic skeletal muscle defects in motor neuron diseases","volume":"4","author":"Boyer","year":"2013","journal-title":"Frontiers in Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0090","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.stem.2012.04.001","article-title":"Tissue-specific stem cells: Lessons from the skeletal muscle satellite cell","volume":"10","author":"Brack","year":"2012","journal-title":"Cell Stem Cell"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0095","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1172\/JCI34022","article-title":"In vivo time-lapse microscopy reveals no loss of murine myonuclei during weeks of muscle atrophy","volume":"118","author":"Bruusgaard","year":"2008","journal-title":"The Journal of Clinical Investigation"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0100","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.devcel.2013.12.020","article-title":"Gene regulatory networks and transcriptional mechanisms that control myogenesis","volume":"28","author":"Buckingham","year":"2014","journal-title":"Developmental Cell"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0105","series-title":"Ueber die degenerations- und Regenerationsvorg\u00e4nge am Nerven nach Verletzungen","author":"B\u00fcngner","year":"1890"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0110","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1006\/exnr.1996.0003","article-title":"Influence of physical parameters of nerve chambers on peripheral nerve regeneration and reinnervation","volume":"137","author":"Buti","year":"1996","journal-title":"Experimental Neurology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0115","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/0092-8674(91)90364-5","article-title":"Agrin mediates cell contact-induced acetylcholine receptor clustering","volume":"67","author":"Campanelli","year":"1991","journal-title":"Cell"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0120","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.4081\/bam.2014.1.5","article-title":"The biology of long-term denervated skeletal muscle","volume":"24","author":"Carlson","year":"2014","journal-title":"European Journal of Translational Myology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0125","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/j.celrep.2014.07.061","article-title":"Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious aging","volume":"8","author":"Carnio","year":"2014","journal-title":"Cell Reports"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0028090","article-title":"Striking denervation of neuromuscular junctions without lumbar motoneuron loss in geriatric mouse muscle","volume":"6","author":"Chai","year":"2011","journal-title":"PloS One"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0135","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/nature11438","article-title":"The aged niche disrupts muscle stem cell quiescence","volume":"490","author":"Chakkalakal","year":"2012","journal-title":"Nature"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0140","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1073\/pnas.67.3.1241","article-title":"Use of a snake venom toxin to characterize the cholinergic receptor protein","volume":"67","author":"Changeux","year":"1970","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0145","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1113\/jphysiol.2009.184085","article-title":"In pursuit of the high-resolution structure of nicotinic acetylcholine receptors","volume":"588","author":"Chen","year":"2010","journal-title":"The Journal of Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0150","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00401-015-1482-4","article-title":"Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury","volume":"130","author":"Chen","year":"2015","journal-title":"Acta Neuropathologica"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0155","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3389\/fncel.2014.00405","article-title":"Neuronal involvement in muscular atrophy","volume":"8","author":"Cisterna","year":"2014","journal-title":"Frontiers in Cellular Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0160","doi-asserted-by":"crossref","first-page":"3901","DOI":"10.1242\/jcs.031047","article-title":"Identity, developmental restriction and reactivity of extralaminar cells capping mammalian neuromuscular junctions","volume":"121","author":"Court","year":"2008","journal-title":"Journal of Cell Science"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0165","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0022-3565(25)08268-0","article-title":"The action of certain esters and ethers of choline, and their relation to muscarine","volume":"6","author":"Dale","year":"1914","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0170","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1113\/jphysiol.1929.sp002598","article-title":"The presence of histamine and acetylcholine in the spleen of the ox and the horse","volume":"68","author":"Dale","year":"1929","journal-title":"The Journal of Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0175","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/nrn3821","article-title":"Neuromuscular synaptogenesis: Coordinating partners with multiple functions","volume":"15","author":"Darabid","year":"2014","journal-title":"Nature Reviews. Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0180","series-title":"Fundamental neuroscience","first-page":"117","article-title":"Chapter 6\u2014Neurotransmitters A2","author":"Deutch","year":"2013"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0185","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1083\/jcb.200407021","article-title":"Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model","volume":"168","author":"Dobrowolny","year":"2005","journal-title":"The Journal of Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0190","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF00713062","article-title":"Excitation-contraction coupling and contractile properties in denervated rat EDL and soleus muscles","volume":"6","author":"Dulhunty","year":"1985","journal-title":"Journal of Muscle Research and Cell Motility"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0195","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0005390","article-title":"Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons","volume":"4","author":"Dupuis","year":"2009","journal-title":"PloS One"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0200","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.coph.2009.03.007","article-title":"Neuromuscular junction destruction during amyotrophic lateral sclerosis: Insights from transgenic models","volume":"9","author":"Dupuis","year":"2009","journal-title":"Current Opinion in Pharmacology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0205","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.nmd.2011.10.009","article-title":"Current status of the congenital myasthenic syndromes","volume":"22","author":"Engel","year":"2012","journal-title":"Neuromuscular Disorders: NMD"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0210","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/nrn1101","article-title":"Sleuthing molecular targets for neurological diseases at the neuromuscular junction","volume":"4","author":"Engel","year":"2003","journal-title":"Nature Reviews. Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0215","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1093\/bja\/aep150","article-title":"Current concepts in neuromuscular transmission","volume":"103","author":"Fagerlund","year":"2009","journal-title":"British Journal of Anaesthesia"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0220","doi-asserted-by":"crossref","first-page":"9599","DOI":"10.1523\/JNEUROSCI.2589-08.2008","article-title":"Schwann cells promote synaptogenesis at the neuromuscular junction via transforming growth factor-beta1","volume":"28","author":"Feng","year":"2008","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0225","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s13539-011-0041-7","article-title":"Molecular control of neuromuscular junction development","volume":"3","author":"Ferraro","year":"2012","journal-title":"Journal of Cachexia, Sarcopenia and Muscle"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0230","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.expneurol.2003.10.004","article-title":"Amyotrophic lateral sclerosis is a distal axonopathy: Evidence in mice and man","volume":"185","author":"Fischer","year":"2004","journal-title":"Experimental Neurology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0235","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.cell.2007.02.035","article-title":"Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals","volume":"129","author":"Fox","year":"2007","journal-title":"Cell"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0240","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1016\/j.cub.2012.07.063","article-title":"Integration of a retrograde signal during synapse formation by glia-secreted TGF-beta ligand","volume":"22","author":"Fuentes-Medel","year":"2012","journal-title":"Current Biology: CB"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0245","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0092-8674(00)81253-2","article-title":"Defective neuromuscular synaptogenesis in agrin-deficient mutant mice","volume":"85","author":"Gautam","year":"1996","journal-title":"Cell"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0250","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/377232a0","article-title":"Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice","volume":"377","author":"Gautam","year":"1995","journal-title":"Nature"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0255","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S1474-4422(15)00145-3","article-title":"Myasthenia gravis: Subgroup classification and therapeutic strategies","volume":"14","author":"Gilhus","year":"2015","journal-title":"The Lancet Neurology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0260","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/j.1469-7793.2001.00627.x","article-title":"Compartmental neurodegeneration and synaptic plasticity in the Wlds mutant mouse","volume":"534","author":"Gillingwater","year":"2001","journal-title":"The Journal of Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0265","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1101\/SQB.1996.061.01.046","article-title":"The receptor tyrosine kinase MuSK is required for neuromuscular junction formation and is a functional receptor for agrin","volume":"61","author":"Glass","year":"1996","journal-title":"Cold Spring Harbor Symposia on Quantitative Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0270","doi-asserted-by":"crossref","first-page":"208","DOI":"10.3389\/fnagi.2014.00208","article-title":"The neuromuscular junction: Aging at the crossroad between nerves and muscle","volume":"6","author":"Gonzalez-Freire","year":"2014","journal-title":"Frontiers in Aging Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0275","doi-asserted-by":"crossref","first-page":"4359","DOI":"10.1073\/pnas.0500711102","article-title":"Syne proteins anchor muscle nuclei at the neuromuscular junction","volume":"102","author":"Grady","year":"2005","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0280","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1002\/glia.20778","article-title":"Biology and pathology of nonmyelinating Schwann cells","volume":"56","author":"Griffin","year":"2008","journal-title":"Glia"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0285","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1242\/jeb.19.1.14","article-title":"The rate of regeneration of nerve","volume":"19","author":"Gutmann","year":"1942","journal-title":"Journal of Experimental Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0290","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1097\/WCO.0b013e328364dc0f","article-title":"Congenital myasthenic syndromes: An update","volume":"26","author":"Hantai","year":"2013","journal-title":"Current Opinion in Neurology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0295","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1083\/jcb.104.6.1623","article-title":"Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection","volume":"104","author":"Heumann","year":"1987","journal-title":"The Journal of Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0300","series-title":"Encyclopedia of Life Sciences (ELS)","article-title":"Neuromuscular junction","author":"Hong","year":"2011"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0305","doi-asserted-by":"crossref","first-page":"4063","DOI":"10.1038\/ncomms5063","article-title":"Intramuscular adipogenesis is inhibited by myo-endothelial progenitors with functioning Bmpr1a signalling","volume":"5","author":"Huang","year":"2014","journal-title":"Nature Communications"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0310","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1016\/j.clinph.2014.06.031","article-title":"Lambert-Eaton myasthenic syndrome\u2014Diagnosis, pathogenesis and therapy","volume":"125","author":"Hulsbrink","year":"2014","journal-title":"Clinical Neurophysiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0315","doi-asserted-by":"crossref","first-page":"04","DOI":"10.12703\/P7-04","article-title":"Spinal muscular atrophy: From tissue specificity to therapeutic strategies","volume":"7","author":"Iascone","year":"2015","journal-title":"F1000Prime Reports"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0320","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1128\/MCB.01036-12","article-title":"Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia","volume":"33","author":"Ibebunjo","year":"2013","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0325","doi-asserted-by":"crossref","first-page":"9957","DOI":"10.1523\/JNEUROSCI.0163-13.2013","article-title":"ProBDNF and mature BDNF as punishment and reward signals for synapse elimination at mouse neuromuscular junctions","volume":"33","author":"Je","year":"2013","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0330","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/35049541","article-title":"Neuronal specification in the spinal cord: Inductive signals and transcriptional codes","volume":"1","author":"Jessell","year":"2000","journal-title":"Nature Reviews. Genetics"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0335","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/ncb2015","article-title":"Muscle injury activates resident fibro\/adipogenic progenitors that facilitate myogenesis","volume":"12","author":"Joe","year":"2010","journal-title":"Nature Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0340","doi-asserted-by":"crossref","first-page":"6323","DOI":"10.1523\/JNEUROSCI.4673-13.2014","article-title":"Terminal Schwann cells participate in neuromuscular synapse remodeling during reinnervation following nerve injury","volume":"34","author":"Kang","year":"2014","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0345","doi-asserted-by":"crossref","first-page":"7087","DOI":"10.1038\/ncomms8087","article-title":"Muscle stem cells contribute to myofibres in sedentary adult mice","volume":"6","author":"Keefe","year":"2015","journal-title":"Nature Communications"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0350","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1097\/00001756-199605310-00021","article-title":"Neuromuscular function impairment is not caused by motor neurone loss in FALS mice: An electromyographic study","volume":"7","author":"Kennel","year":"1996","journal-title":"Neuroreport"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0355","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.cell.2008.10.002","article-title":"Lrp4 is a receptor for Agrin and forms a complex with MuSK","volume":"135","author":"Kim","year":"2008","journal-title":"Cell"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0360","series-title":"\u00dcber die peripherischen Endorgane der motorischen Nerven","author":"K\u00fchne","year":"1862"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0365","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.conb.2005.12.003","article-title":"Assembly of the postsynaptic membrane at the neuromuscular junction: Paradigm lost","volume":"16","author":"Kummer","year":"2006","journal-title":"Current Opinion in Neurobiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0370","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a006023","article-title":"Signaling in muscle contraction","volume":"7","author":"Kuo","year":"2015","journal-title":"Cold Spring Harbor Perspectives in Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0375","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/791679","article-title":"Sarcopenia, a neurogenic syndrome?","volume":"2013","author":"Kwan","year":"2013","journal-title":"Journal of Aging Research"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0380","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1113\/jphysiol.1905.sp001128","article-title":"On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari","volume":"33","author":"Langley","year":"1905","journal-title":"The Journal of Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0385","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0301-0082(95)98601-Z","article-title":"Effects of ageing on the motor unit","volume":"45","author":"Larsson","year":"1995","journal-title":"Progress in Neurobiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0390","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.1242\/dev.067595","article-title":"An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration","volume":"138","author":"Lepper","year":"2011","journal-title":"Development"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0395","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1113\/jphysiol.1972.sp009787","article-title":"The effect of denervation on the mechanical and electrical responses of fast and slow mammalian twitch muscle","volume":"222","author":"Lewis","year":"1972","journal-title":"The Journal of Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0400","doi-asserted-by":"crossref","first-page":"14910","DOI":"10.1523\/JNEUROSCI.3590-11.2011","article-title":"Changes in aging mouse neuromuscular junctions are explained by degeneration and regeneration of muscle fiber segments at the synapse","volume":"31","author":"Li","year":"2011","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0405","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1038\/35074025","article-title":"Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse","volume":"410","author":"Lin","year":"2001","journal-title":"Nature"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0410","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.neuron.2005.04.002","article-title":"Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism","volume":"46","author":"Lin","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb9000","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.26464","article-title":"Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration","volume":"6","author":"Liu","year":"2017","journal-title":"eLife"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0415","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.09221","article-title":"Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions","volume":"4","author":"Liu","year":"2015","journal-title":"eLife"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0420","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/bpa.12350","article-title":"The role of skeletal muscle in amyotrophic lateral sclerosis","volume":"26","author":"Loeffler","year":"2016","journal-title":"Brain Pathology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0425","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1007\/s13670-015-0127-8","article-title":"Amyotrophic lateral sclerosis: An aging-related disease","volume":"4","author":"Logroscino","year":"2015","journal-title":"Current Geriatrics Reports"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0430","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1126\/science.aad5725","article-title":"Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy","volume":"351","author":"Long","year":"2016","journal-title":"Science"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0435","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1126\/science.1254445","article-title":"Prevention of muscular dystrophy in mice by CRISPR\/Cas9-mediated editing of germline DNA","volume":"345","author":"Long","year":"2014","journal-title":"Science"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0440","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.pediatrneurol.2011.12.001","article-title":"Congenital myasthenic syndrome: A brief review","volume":"46","author":"Lorenzoni","year":"2012","journal-title":"Pediatric Neurology"},{"issue":"Suppl 11","key":"10.1016\/bs.ctdb.2017.08.005_bb0445","article-title":"\u201cMix of Mics\u201d\u2014Phenotypic and biological heterogeneity of \u201cmultipotent\u201d muscle interstitial cells (MICs)","volume":"004","author":"Malecova","year":"2012","journal-title":"Journal of Stem Cell Research & Therapy"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0450","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1242\/dev.068858","article-title":"Effective fiber hypertrophy in satellite cell-depleted skeletal muscle","volume":"138","author":"McCarthy","year":"2011","journal-title":"Development"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0455","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/317066a0","article-title":"Concentration of acetylcholine receptor mRNA in synaptic regions of adult muscle fibres","volume":"317","author":"Merlie","year":"1985","journal-title":"Nature"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0460","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1113\/jphysiol.1970.sp009076","article-title":"On the degeneration of rat neuromuscular junctions after nerve section","volume":"207","author":"Miledi","year":"1970","journal-title":"The Journal of Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0465","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0896-6273(02)01020-6","article-title":"Roles of neurotransmitter in synapse formation: Development of neuromuscular junctions lacking choline acetyltransferase","volume":"36","author":"Misgeld","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0470","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/ncb2025","article-title":"Identification and characterization of a non-satellite cell muscle resident progenitor during postnatal development","volume":"12","author":"Mitchell","year":"2010","journal-title":"Nature Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0475","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1083\/jcb.200909117","article-title":"The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice","volume":"188","author":"Mittal","year":"2010","journal-title":"The Journal of Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0480","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/nature01748","article-title":"Structure and gating mechanism of the acetylcholine receptor pore","volume":"423","author":"Miyazawa","year":"2003","journal-title":"Nature"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0485","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3389\/fnins.2014.00252","article-title":"ALS as a distal axonopathy: Molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease","volume":"8","author":"Moloney","year":"2014","journal-title":"Frontiers in Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0490","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cell.2010.09.004","article-title":"Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases","volume":"143","author":"Moresi","year":"2010","journal-title":"Cell"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0495","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1242\/dev.064162","article-title":"Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration","volume":"138","author":"Murphy","year":"2011","journal-title":"Development"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0500","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1365-2990.2010.01061.x","article-title":"Review: Neuromuscular synaptic vulnerability in motor neurone disease: Amyotrophic lateral sclerosis and spinal muscular atrophy","volume":"36","author":"Murray","year":"2010","journal-title":"Neuropathology and Applied Neurobiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0505","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1126\/science.aad5143","article-title":"In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy","volume":"351","author":"Nelson","year":"2016","journal-title":"Science"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0510","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1126\/science.279.5357.1725","article-title":"Hyperinnervation of neuromuscular junctions caused by GDNF overexpression in muscle","volume":"279","author":"Nguyen","year":"1998","journal-title":"Science"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0515","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/nn905","article-title":"Pre-existing pathways promote precise projection patterns","volume":"5","author":"Nguyen","year":"2002","journal-title":"Nature Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0520","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1038\/nature03112","article-title":"A synaptic laminin-calcium channel interaction organizes active zones in motor nerve terminals","volume":"432","author":"Nishimune","year":"2004","journal-title":"Nature"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0525","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1083\/jcb.200805095","article-title":"Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction","volume":"182","author":"Nishimune","year":"2008","journal-title":"The Journal of Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0530","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0022-510X(84)90021-2","article-title":"Age changes of motor innervation and acetylcholine receptor distribution on human skeletal muscle fibres","volume":"66","author":"Oda","year":"1984","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0535","doi-asserted-by":"crossref","first-page":"C447","DOI":"10.1152\/ajpcell.00451.2011","article-title":"Denervation-induced mitochondrial dysfunction and autophagy in skeletal muscle of apoptosis-deficient animals","volume":"303","author":"O'Leary","year":"2012","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0540","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1083\/jcb.201006098","article-title":"Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice","volume":"191","author":"Paul","year":"2010","journal-title":"The Journal of Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0545","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0896-6273(03)00682-2","article-title":"Glial cells maintain synaptic structure and function and promote development of the neuromuscular junction in vivo","volume":"40","author":"Reddy","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0550","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1242\/dev.069088","article-title":"Satellite cells are essential for skeletal muscle regeneration: The cell on the edge returns centre stage","volume":"139","author":"Relaix","year":"2012","journal-title":"Development"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0555","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neuron.2011.09.010","article-title":"A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD","volume":"72","author":"Renton","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0560","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1523\/JNEUROSCI.09-05-01781.1989","article-title":"In vivo visualization of pre- and postsynaptic changes during synapse elimination in reinnervated mouse muscle","volume":"9","author":"Rich","year":"1989","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0565","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0029082","article-title":"Denervation causes fiber atrophy and myosin heavy chain co-expression in senescent skeletal muscle","volume":"7","author":"Rowan","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0570","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0301-0082(85)90018-8","article-title":"Nicotinic acetylcholine receptors in vertebrate muscle: Properties, distribution and neural control","volume":"25","author":"Salpeter","year":"1985","journal-title":"Progress in Neurobiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0575","doi-asserted-by":"crossref","first-page":"3647","DOI":"10.1242\/dev.067587","article-title":"Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration","volume":"138","author":"Sambasivan","year":"2011","journal-title":"Development"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0580","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1146\/annurev.neuro.22.1.389","article-title":"Development of the vertebrate neuromuscular junction","volume":"22","author":"Sanes","year":"1999","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0585","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1038\/35097557","article-title":"Induction, assembly, maturation and maintenance of a postsynaptic apparatus","volume":"2","author":"Sanes","year":"2001","journal-title":"Nature Reviews. Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0590","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1083\/jcb.78.1.176","article-title":"Reinnervation of muscle fiber basal lamina after removal of myofibers. Differentiation of regenerating axons at original synaptic sites","volume":"78","author":"Sanes","year":"1978","journal-title":"The Journal of Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0595","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1038\/ng.2772","article-title":"BMP signaling controls muscle mass","volume":"45","author":"Sartori","year":"2013","journal-title":"Nature Genetics"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0600","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0896-6273(01)00353-1","article-title":"Targeting transcription to the neuromuscular synapse","volume":"31","author":"Schaeffer","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0605","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1152\/physrev.00031.2010","article-title":"Fiber types in mammalian skeletal muscles","volume":"91","author":"Schiaffino","year":"2011","journal-title":"Physiological Reviews"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0610","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1242\/dev.114.3.545","article-title":"Spatial restriction of AChR gene expression to subsynaptic nuclei","volume":"114","author":"Simon","year":"1992","journal-title":"Development"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0615","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1002\/dneu.20953","article-title":"Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction","volume":"71","author":"Singhal","year":"2011","journal-title":"Developmental Neurobiology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0620","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0896-6273(95)90246-5","article-title":"Schwann cell processes guide regeneration of peripheral axons","volume":"14","author":"Son","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0625","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.tem.2015.03.006","article-title":"Muscle stem cell aging: Regulation and rejuvenation","volume":"26","author":"Sousa-Victor","year":"2015","journal-title":"Trends in Endocrinology and Metabolism: TEM"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0630","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1126\/science.aad5177","article-title":"In vivo gene editing in dystrophic mouse muscle and muscle stem cells","volume":"351","author":"Tabebordbar","year":"2016","journal-title":"Science"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0635","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1152\/physrev.00033.2014","article-title":"Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting","volume":"95","author":"Tintignac","year":"2015","journal-title":"Physiological Reviews"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0640","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0022-510X(77)90069-7","article-title":"The numbers of limb motor neurons in the human lumbosacral cord throughout life","volume":"34","author":"Tomlinson","year":"1977","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0645","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/373037a0","article-title":"Acetylcholine receptor channel imaged in the open state","volume":"373","author":"Unwin","year":"1995","journal-title":"Nature"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0650","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.jmb.2004.12.031","article-title":"Refined structure of the nicotinic acetylcholine receptor at 4A resolution","volume":"346","author":"Unwin","year":"2005","journal-title":"Journal of Molecular Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0655","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.jmb.2012.07.010","article-title":"Gating movement of acetylcholine receptor caught by plunge-freezing","volume":"422","author":"Unwin","year":"2012","journal-title":"Journal of Molecular Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0660","doi-asserted-by":"crossref","first-page":"14863","DOI":"10.1073\/pnas.1002220107","article-title":"Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise","volume":"107","author":"Valdez","year":"2010","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0665","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1523\/JNEUROSCI.5080-07.2008","article-title":"Evidence for muscle-dependent neuromuscular synaptic site determination in mammals","volume":"28","author":"Vock","year":"2008","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0670","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0896-6273(02)01142-X","article-title":"In vivo time-lapse imaging of synaptic takeover associated with naturally occurring synapse elimination","volume":"37","author":"Walsh","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb9005","doi-asserted-by":"crossref","first-page":"24849","DOI":"10.1038\/srep24849","article-title":"Age-related fragmentation of the motor endplate is not associated with impaired neuromuscular transmission in the mouse diaphragm","volume":"6","author":"Willadt","year":"2016","journal-title":"Scientific Report"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0675","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1126\/science.1181046","article-title":"MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice","volume":"326","author":"Williams","year":"2009","journal-title":"Science"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0680","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1083\/jcb.201211134","article-title":"The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass","volume":"203","author":"Winbanks","year":"2013","journal-title":"The Journal of Cell Biology"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0685","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0022-510X(90)90076-Y","article-title":"Morphological changes in the human end plate with age","volume":"95","author":"Wokke","year":"1990","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0690","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1093\/hmg\/ddq106","article-title":"Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice","volume":"19","author":"Wong","year":"2010","journal-title":"Human Molecular Genetics"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0695","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1242\/dev.038711","article-title":"To build a synapse: Signaling pathways in neuromuscular junction assembly","volume":"137","author":"Wu","year":"2010","journal-title":"Development"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0700","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0896-6273(01)00287-2","article-title":"Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation","volume":"30","author":"Yang","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0705","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1523\/JNEUROSCI.03-01-00225.1983","article-title":"Rapid lateral diffusion of extrajunctional acetylcholine receptors in the developing muscle membrane of Xenopus tadpole","volume":"3","author":"Young","year":"1983","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0710","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1242\/dev.02783","article-title":"Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation","volume":"134","author":"Zhang","year":"2007","journal-title":"Development"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0715","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.cmet.2007.11.004","article-title":"FoxO3 coordinately activates protein degradation by the autophagic\/lysosomal and proteasomal pathways in atrophying muscle cells","volume":"6","author":"Zhao","year":"2007","journal-title":"Cell Metabolism"},{"key":"10.1016\/bs.ctdb.2017.08.005_bb0720","doi-asserted-by":"crossref","first-page":"3465","DOI":"10.1523\/JNEUROSCI.2934-16.2017","article-title":"Muscle yap is a regulator of neuromuscular junction formation and regeneration","volume":"37","author":"Zhao","year":"2017","journal-title":"The Journal of Neuroscience: The Official Journal of the Society for Neuroscience."}],"container-title":["Current Topics in Developmental Biology","Myogenesis in Development and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0070215317300455?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0070215317300455?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T23:56:45Z","timestamp":1750982205000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0070215317300455"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9780128092156"],"references-count":145,"URL":"https:\/\/doi.org\/10.1016\/bs.ctdb.2017.08.005","relation":{},"ISSN":["0070-2153"],"issn-type":[{"value":"0070-2153","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}