{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:25:11Z","timestamp":1786983911580,"version":"build-2736575974"},"reference-count":132,"publisher":"Elsevier","isbn-type":[{"value":"9780443414251","type":"print"}],"license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100020884","name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo","doi-asserted-by":"publisher","award":["21230122"],"award-info":[{"award-number":["21230122"]}],"id":[{"id":"10.13039\/501100020884","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020884","name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo","doi-asserted-by":"publisher","award":["21251360"],"award-info":[{"award-number":["21251360"]}],"id":[{"id":"10.13039\/501100020884","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100032816","name":"Universidad San Sebasti\u00e1n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100032816","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["1240623"],"award-info":[{"award-number":["1240623"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["13240033"],"award-info":[{"award-number":["13240033"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/bs.ircmb.2025.08.005","type":"book-chapter","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T04:48:23Z","timestamp":1758602903000},"page":"1-28","source":"Crossref","is-referenced-by-count":1,"title":["Autophagy and primary cilium: A dynamic duo in cellular homeostasis and disease"],"prefix":"10.1016","author":[{"given":"Javiera","family":"Acevedo-Valdivieso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Sandoval-Valenzuela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Pinto-N\u00fa\u00f1ez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isidora","family":"Reyes-Risso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yorka","family":"Cheuquemilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Acu\u00f1a-Catal\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia V.","family":"Burgos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenia","family":"Morselli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib1","first-page":"2380","article-title":"Revisiting leptin\u2019s role in obesity and weight loss","volume":"118","author":"Ahima","year":"2008","journal-title":"The Journal of Clinical Investigation"},{"issue":"Pt 2","key":"10.1016\/bs.ircmb.2025.08.005_bib2","first-page":"277","article-title":"Cilia in cell-cultured fibroblasts. Ii. incidence in mitotic and post-mitotic BHK 21-C13 fibroblasts","volume":"109","author":"Archer","year":"1971","journal-title":"Journal of Anatomy"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/s41419-022-05109-9","article-title":"Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism","volume":"13","author":"Avalos","year":"2022","journal-title":"Cell Death & Disease"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib4","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1083\/jcb.200803137","article-title":"Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum","volume":"182","author":"Axe","year":"2008","journal-title":"The Journal of Cell Biology"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib5","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1146\/annurev.genom.7.080505.115610","article-title":"The ciliopathies: An emerging class of human genetic disorders","volume":"7","author":"Badano","year":"2006","journal-title":"Annual Review of Genomics and Human Genetics"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib6","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1038\/ejhg.2014.174","article-title":"Meckel-Gruber syndrome: A population-based study on prevalence, prenatal diagnosis, clinical features, and survival in Europe","volume":"23","author":"Barisic","year":"2015","journal-title":"European Journal of Human Genetics: EJHG"},{"issue":"13","key":"10.1016\/bs.ircmb.2025.08.005_bib7","doi-asserted-by":"crossref","first-page":"R526","DOI":"10.1016\/j.cub.2009.05.025","article-title":"The primary cilium as a complex signaling center","volume":"19","author":"Berbari","year":"2009","journal-title":"Current Biology: CB"},{"issue":"5","key":"10.1016\/bs.ircmb.2025.08.005_bib8","article-title":"Liver fibrosis and steatosis in alstrom syndrome: a genetic model for metabolic syndrome","volume":"11","author":"Bettini","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib9","doi-asserted-by":"crossref","first-page":"4814","DOI":"10.1038\/s41467-021-25079-4","article-title":"Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis","volume":"12","author":"Bodineau","year":"2021","journal-title":"Nature Communications"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib10","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1080\/15548627.2021.1935004","article-title":"When the autophagy protein ATG16L1 met the ciliary protein IFT20","volume":"17","author":"Boukhalfa","year":"2021","journal-title":"Autophagy"},{"issue":"9","key":"10.1016\/bs.ircmb.2025.08.005_bib11","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1091\/mbc.E18-11-0743","article-title":"Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex","volume":"30","author":"Brier","year":"2019","journal-title":"Molecular Biology of the Cell"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib12","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.83205","article-title":"Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects","volume":"12","author":"Chen","year":"2023","journal-title":"Elife"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.1046248","article-title":"Autophagy and the primary cilium in cell metabolism: what\u2019s upstream?","volume":"10","author":"Claude-Taupin","year":"2022","journal-title":"Frontiers in Cell and Developmental Biology"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib14","doi-asserted-by":"crossref","first-page":"8056","DOI":"10.1038\/s41467-023-43775-1","article-title":"The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells","volume":"14","author":"Claude-Taupin","year":"2023","journal-title":"Nature Communications"},{"issue":"3","key":"10.1016\/bs.ircmb.2025.08.005_bib15","doi-asserted-by":"crossref","first-page":"532","DOI":"10.4161\/auto.27641","article-title":"\u201cCiliophagy\u201d: the consumption of cilia components by autophagy","volume":"10","author":"Cloonan","year":"2014","journal-title":"Autophagy"},{"issue":"10174","key":"10.1016\/bs.ircmb.2025.08.005_bib16","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/S0140-6736(18)32782-X","article-title":"Autosomal dominant polycystic kidney disease","volume":"393","author":"Cornec-Le Gall","year":"2019","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/bs.ircmb.2025.08.005_bib17","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1007\/s12020-021-02643-y","article-title":"Alstrom syndrome: An ultra-rare monogenic disorder as a model for insulin resistance, type 2 diabetes mellitus and obesity","volume":"71","author":"Dassie","year":"2021","journal-title":"Endocrine"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib18","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41580-018-0003-4","article-title":"Mechanism and medical implications of mammalian autophagy","volume":"19","author":"Dikic","year":"2018","journal-title":"Nature Reviews. Molecular Cell Biology"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib19","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.2215\/CJN.05611207","article-title":"Mammalian target of rapamycin and caspase inhibitors in polycystic kidney disease","volume":"3","author":"Edelstein","year":"2008","journal-title":"Clinical Journal of the American Society of Nephrology: CJASN"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20061336","article-title":"Primary cilium in cancer hallmarks","volume":"20","author":"Fabbri","year":"2019","journal-title":"International Journal of Molecular Sciences"},{"issue":"9","key":"10.1016\/bs.ircmb.2025.08.005_bib21","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1038\/ng1419","article-title":"Abnormal cerebellar development and axonal decussation due to mutations in AHI1 in joubert syndrome","volume":"36","author":"Ferland","year":"2004","journal-title":"Nature Genetics"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib22","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/ng1684","article-title":"Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification","volume":"38","author":"Ferrante","year":"2006","journal-title":"Nature Genetics"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib23","article-title":"The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in t cells","volume":"9","author":"Finetti","year":"2021","journal-title":"Frontiers in\u00a0Cell\u00a0and\u00a0Developmental Biology"},{"issue":"11","key":"10.1016\/bs.ircmb.2025.08.005_bib24","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/nrm2278","article-title":"When cilia go bad: Cilia defects and ciliopathies","volume":"8","author":"Fliegauf","year":"2007","journal-title":"Nature Reviews Molecular Cell Biology"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib25","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.biochi.2015.09.011","article-title":"The size of the primary cilium and acetylated tubulin are modulated during adipocyte differentiation: analysis of HDAC6 functions in these processes","volume":"124","author":"Forcioli-Conti","year":"2016","journal-title":"Biochimie"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib26","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.201912098","article-title":"A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy","volume":"219","author":"Fracchiolla","year":"2020","journal-title":"The Journal of Cell Biology"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib27","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/humu.20614","article-title":"Mutations of the CEP290 gene encoding a centrosomal protein cause Meckel-Gruber syndrome","volume":"29","author":"Frank","year":"2008","journal-title":"Human Mutation"},{"issue":"5","key":"10.1016\/bs.ircmb.2025.08.005_bib28","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1091\/mbc.e07-12-1257","article-title":"The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy","volume":"19","author":"Fujita","year":"2008","journal-title":"Molecular Biology of the Cell"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib29","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1038\/s41598-024-51406-y","article-title":"Regulation of mitochondrial metabolism by autophagy supports leptin-induced cell migration","volume":"14","author":"Garcia-Miranda","year":"2024","journal-title":"Scientific Reports"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2024.167256","article-title":"PKD2 regulates autophagy and forms a protein complex with BECN1 at the primary cilium of hypothalamic neuronal cells","volume":"1870","author":"Garcia-Navarrete","year":"2024","journal-title":"Biochimica et Biophysica Acta - Molecular Basis of Disease"},{"issue":"11","key":"10.1016\/bs.ircmb.2025.08.005_bib31","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1111\/liv.13163","article-title":"Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with alstrom syndrome","volume":"36","author":"Gathercole","year":"2016","journal-title":"Liver International: Official Journal of the International Association for the Study of the Liver"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib32","doi-asserted-by":"crossref","first-page":"5308","DOI":"10.1038\/ncomms6308","article-title":"Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents","volume":"5","author":"Gerdes","year":"2014","journal-title":"Nature Communications"},{"issue":"15","key":"10.1016\/bs.ircmb.2025.08.005_bib33","doi-asserted-by":"crossref","DOI":"10.3390\/cells11152262","article-title":"Autophagy: a key regulator of homeostasis and disease: An overview of molecular mechanisms and modulators","volume":"11","author":"Gomez-Virgilio","year":"2022","journal-title":"Cells"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib34","doi-asserted-by":"crossref","first-page":"243","DOI":"10.14348\/molcells.2017.0054","article-title":"The ciliary transition zone: finding the pieces and assembling the gate","volume":"40","author":"Goncalves","year":"2017","journal-title":"Molecules and Cells"},{"issue":"21","key":"10.1016\/bs.ircmb.2025.08.005_bib35","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2023113891","article-title":"Emerging principles of primary cilia dynamics in controlling tissue organization and function","volume":"42","author":"Gopalakrishnan","year":"2023","journal-title":"The EMBO Journal"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib36","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1158\/0008-5472.CAN-12-2938","article-title":"HDAC6 inhibition restores ciliary expression and decreases tumor growth","volume":"73","author":"Gradilone","year":"2013","journal-title":"Cancer Research"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib37","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.cellsig.2016.02.018","article-title":"Modulation of primary cilia length by melanin-concentrating hormone receptor 1","volume":"28","author":"Hamamoto","year":"2016","journal-title":"Cellular Signalling"},{"issue":"5","key":"10.1016\/bs.ircmb.2025.08.005_bib38","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1172\/JCI69395","article-title":"Leptin-promoted cilia assembly is critical for normal energy balance","volume":"124","author":"Han","year":"2014","journal-title":"The Journal of Clinical Investigation"},{"issue":"9","key":"10.1016\/bs.ircmb.2025.08.005_bib39","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000414","article-title":"Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons","volume":"17","author":"Haq","year":"2019","journal-title":"PLoS Biology"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib40","doi-asserted-by":"crossref","first-page":"244","DOI":"10.3389\/fped.2017.00244","article-title":"Meckel-Gruber syndrome: An update on diagnosis, clinical management, and research advances","volume":"5","author":"Hartill","year":"2017","journal-title":"Frontiers in Pediatrics"},{"issue":"17","key":"10.1016\/bs.ircmb.2025.08.005_bib41","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.15252\/embj.201593148","article-title":"Autophagosome-lysosome fusion in neurons requires INPP5E, a protein associated with joubert syndrome","volume":"35","author":"Hasegawa","year":"2016","journal-title":"The EMBO Journal"},{"issue":"2","key":"10.1016\/bs.ircmb.2025.08.005_bib42","doi-asserted-by":"crossref","first-page":"264","DOI":"10.4103\/1673-5374.377414","article-title":"Role of lipids in the control of autophagy and primary cilium signaling in neurons","volume":"19","author":"Hernandez-Caceres","year":"2024","journal-title":"Neural Regeneration Research"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib43","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3389\/fendo.2019.00176","article-title":"Palmitic acid reduces the autophagic flux and insulin sensitivity through the activation of the free fatty acid receptor 1 (FFAR1) in the hypothalamic neuronal cell line N43\/5","volume":"10","author":"Hernandez-Caceres","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"10.1016\/bs.ircmb.2025.08.005_bib44","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nrm.2017.95","article-title":"AMPK: guardian of metabolism and mitochondrial homeostasis","volume":"19","author":"Herzig","year":"2018","journal-title":"Nature Reviews. Molecular Cell Biology"},{"issue":"5","key":"10.1016\/bs.ircmb.2025.08.005_bib45","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.devcel.2012.09.019","article-title":"Arl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortex","volume":"23","author":"Higginbotham","year":"2012","journal-title":"Developmental Cell"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib46","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.cell.2019.11.005","article-title":"Omega-3 fatty acids activate ciliary FFAR4 to control adipogenesis","volume":"179","author":"Hilgendorf","year":"2019","journal-title":"Cell"},{"issue":"5","key":"10.1016\/bs.ircmb.2025.08.005_bib47","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.tins.2024.03.004","article-title":"The neuronal cilium - a highly diverse and dynamic organelle involved in sensory detection and neuromodulation","volume":"47","author":"Jurisch-Yaksi","year":"2024","journal-title":"Trends in Neurosciences"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib48","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/cdd.2010.191","article-title":"The beclin 1 network regulates autophagy and apoptosis","volume":"18","author":"Kang","year":"2011","journal-title":"Cell Death and Differentiation"},{"issue":"8","key":"10.1016\/bs.ircmb.2025.08.005_bib49","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nrm4024","article-title":"Autophagy at the crossroads of catabolism and anabolism","volume":"16","author":"Kaur","year":"2015","journal-title":"Nature Reviews Molecular Cell Biology"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib50","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/cge.12614","article-title":"Exploration of the cognitive, adaptive and behavioral functioning of patients affected with Bardet-Biedl syndrome","volume":"89","author":"Kerr","year":"2016","journal-title":"Clinical Genetics"},{"issue":"2","key":"10.1016\/bs.ircmb.2025.08.005_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0118190","article-title":"Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells","volume":"10","author":"Kim","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib52","doi-asserted-by":"crossref","first-page":"337","DOI":"10.4062\/biomolther.2019.056","article-title":"Interplay between primary cilia and autophagy and its controversial roles in cancer","volume":"27","author":"Ko","year":"2019","journal-title":"Biomolecules & Therapeutics (Seoul)"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib53","doi-asserted-by":"crossref","DOI":"10.3390\/genes11060711","article-title":"Reciprocal regulation between primary cilia and mTORC1","volume":"11","author":"Lai","year":"2020","journal-title":"Genes (Basel)"},{"issue":"12","key":"10.1016\/bs.ircmb.2025.08.005_bib54","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.tibs.2015.09.003","article-title":"IFT-Cargo interactions and protein transport in cilia","volume":"40","author":"Lechtreck","year":"2015","journal-title":"Trends in Biochemical Sciences"},{"issue":"11","key":"10.1016\/bs.ircmb.2025.08.005_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0015394","article-title":"The association of AMPK with ULK1 regulates autophagy","volume":"5","author":"Lee","year":"2010","journal-title":"PLoS One"},{"issue":"15","key":"10.1016\/bs.ircmb.2025.08.005_bib56","doi-asserted-by":"crossref","first-page":"R724","DOI":"10.1016\/j.cub.2024.06.044","article-title":"Metabolism: secretory autophagy balances nutrient supply and demand","volume":"34","author":"Leidal","year":"2024","journal-title":"Current Biology: CB"},{"issue":"8","key":"10.1016\/bs.ircmb.2025.08.005_bib57","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1111\/jcmm.13091","article-title":"Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1\/cyclin axis","volume":"21","author":"Li","year":"2017","journal-title":"Journal of Cellular and Molecular Medicine"},{"issue":"5","key":"10.1016\/bs.ircmb.2025.08.005_bib58","doi-asserted-by":"crossref","first-page":"784","DOI":"10.7150\/ijms.92766","article-title":"The characterization and comorbidities of heterozygous Bardet-Biedl syndrome carriers","volume":"21","author":"Li","year":"2024","journal-title":"International Journal of Medical Sciences"},{"issue":"15","key":"10.1016\/bs.ircmb.2025.08.005_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e35665","article-title":"Leptin protects chondrocytes by inhibiting autophagy via phosphoinositide 3 kinase\/protein kinase b\/mammalian target of rapamycin signaling pathway","volume":"10","author":"Li","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib60","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-981-15-0602-4_2","article-title":"Regulation of ATG and autophagy initiation","volume":"1206","author":"Li","year":"2019","journal-title":"Advances in Experimental Medicine and Biology"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib61","doi-asserted-by":"crossref","first-page":"500","DOI":"10.4161\/auto.5829","article-title":"The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates","volume":"4","author":"Lindmo","year":"2008","journal-title":"Autophagy"},{"issue":"21","key":"10.1016\/bs.ircmb.2025.08.005_bib62","doi-asserted-by":"crossref","first-page":"4383","DOI":"10.1093\/hmg\/ddt288","article-title":"Birt-Hogg-Dube syndrome is a novel ciliopathy","volume":"22","author":"Luijten","year":"2013","journal-title":"Human Molecular Genetics"},{"issue":"11","key":"10.1016\/bs.ircmb.2025.08.005_bib63","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.tcb.2023.05.005","article-title":"Regulation of the length of neuronal primary cilia and its potential effects on signalling","volume":"33","author":"Macarelli","year":"2023","journal-title":"Trends in Cell Biology"},{"issue":"4 Pt B","key":"10.1016\/bs.ircmb.2025.08.005_bib64","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.bbadis.2017.06.006","article-title":"The cholangiocyte primary cilium in health and disease","volume":"1864","author":"Mansini","year":"2018","journal-title":"Biochimica et Biophysica Acta - Molecular Basis of Disease"},{"issue":"12","key":"10.1016\/bs.ircmb.2025.08.005_bib65","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1038\/sj.ejhg.5201933","article-title":"Alstrom syndrome","volume":"15","author":"Marshall","year":"2007","journal-title":"European Journal of Human Genetics: EJHG"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib66","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/s41576-023-00587-9","article-title":"Primary cilia as dynamic and diverse signalling hubs in development and disease","volume":"24","author":"Mill","year":"2023","journal-title":"Nature Reviews. Genetics"},{"issue":"10","key":"10.1016\/bs.ircmb.2025.08.005_bib67","doi-asserted-by":"crossref","first-page":"6071","DOI":"10.1074\/jbc.M114.605345","article-title":"Inhibition of autophagic turnover in beta-cells by fatty acids and glucose leads to apoptotic cell death","volume":"290","author":"Mir","year":"2015","journal-title":"The Journal of Biological Chemistry"},{"issue":"22","key":"10.1016\/bs.ircmb.2025.08.005_bib68","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.1101\/gad.1599207","article-title":"Autophagy: Process and function","volume":"21","author":"Mizushima","year":"2007","journal-title":"Genes & Development"},{"issue":"3","key":"10.1016\/bs.ircmb.2025.08.005_bib69","doi-asserted-by":"crossref","first-page":"33","DOI":"10.15698\/cst2021.03.244","article-title":"The OFD1 protein is a novel player in selective autophagy: another tile to the cilia\/autophagy puzzle","volume":"5","author":"Morleo","year":"2021","journal-title":"Cell Stress"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib70","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1080\/15548627.2022.2067383","article-title":"Crosstalk between cilia and autophagy: implication for human diseases","volume":"19","author":"Morleo","year":"2023","journal-title":"Autophagy"},{"issue":"5","key":"10.1016\/bs.ircmb.2025.08.005_bib71","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s00439-010-0804-9","article-title":"Identification of 28 novel mutations in the Bardet-Biedl syndrome genes: the burden of private mutations in an extensively heterogeneous disease","volume":"127","author":"Muller","year":"2010","journal-title":"Human Genetics"},{"issue":"8","key":"10.1016\/bs.ircmb.2025.08.005_bib72","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/s41419-024-06972-4","article-title":"CYLD\/HDAC6 signaling regulates the interplay between epithelial-mesenchymal transition and ciliary homeostasis during pulmonary fibrosis","volume":"15","author":"Ni","year":"2024","journal-title":"Cell Death Dis"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib73","doi-asserted-by":"crossref","first-page":"577","DOI":"10.2215\/CJN.13291019","article-title":"Metabolic reprogramming in autosomal dominant polycystic kidney disease: Evidence and therapeutic potential","volume":"15","author":"Nowak","year":"2020","journal-title":"Clinical Journal of the American Society of Nephrology: CJASN"},{"issue":"7050","key":"10.1016\/bs.ircmb.2025.08.005_bib74","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/nature03818","article-title":"Functional coordination of intraflagellar transport motors","volume":"436","author":"Ou","year":"2005","journal-title":"Nature"},{"issue":"5","key":"10.1016\/bs.ircmb.2025.08.005_bib75","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.cmet.2024.02.010","article-title":"Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia","volume":"36","author":"Oya","year":"2024","journal-title":"Cell Metabolism"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib76","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ceb.2016.01.008","article-title":"Autophagy and primary cilia: Dual interplay","volume":"39","author":"Pampliega","year":"2016","journal-title":"Current Opinion in Cell Biology"},{"issue":"7470","key":"10.1016\/bs.ircmb.2025.08.005_bib77","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/nature12639","article-title":"Functional interaction between autophagy and ciliogenesis","volume":"502","author":"Pampliega","year":"2013","journal-title":"Nature"},{"issue":"1-2","key":"10.1016\/bs.ircmb.2025.08.005_bib78","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3233\/TRD-190041","article-title":"The molecular genetics of joubert syndrome and related ciliopathies: the challenges of genetic and phenotypic heterogeneity","volume":"4","author":"Parisi","year":"2019","journal-title":"Translational Science of Rare Diseases"},{"issue":"3","key":"10.1016\/bs.ircmb.2025.08.005_bib79","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4330\/wjc.v16.i3.109","article-title":"Mechanistic insights into fasting-induced autophagy in the aging heart","volume":"16","author":"Parvaresh","year":"2024","journal-title":"World Journal of Cardiology"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib80","first-page":"G1022","article-title":"HDAC6-dependent ciliophagy is involved in ciliary loss and cholangiocarcinoma growth in human cells and murine models","volume":"318","author":"Peixoto","year":"2020","journal-title":"American Journal of"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib81","article-title":"Autophagy in aging-related oral diseases","volume":"13","author":"Pena-Oyarzun","year":"2022","journal-title":"Frontiers in Endocrinology (Lausanne)"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib82","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0091-679X(08)94007-3","article-title":"Primary cilia and the cell cycle","volume":"94","author":"Plotnikova","year":"2009","journal-title":"Methods in Cell Biology"},{"issue":"19","key":"10.1016\/bs.ircmb.2025.08.005_bib83","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241914666","article-title":"Autosomal dominant polycystic kidney disease: Is there a role for autophagy?","volume":"24","author":"Ponticelli","year":"2023","journal-title":"International Journal of Molecular Sciences"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib84","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00232-002-1042-4","article-title":"Removal of the MDCK cell primary cilium abolishes flow sensing","volume":"191","author":"Praetorius","year":"2003","journal-title":"The Journal of Membrane Biology"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib85","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/embor.2012.73","article-title":"The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization","volume":"13","author":"Reiter","year":"2012","journal-title":"EMBO Reports"},{"issue":"11","key":"10.1016\/bs.ircmb.2025.08.005_bib86","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/nrm952","article-title":"Intraflagellar transport","volume":"3","author":"Rosenbaum","year":"2002","journal-title":"Nature Reviews Molecular Cell Biology"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib87","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.2337\/db13-1622","article-title":"Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans","volume":"63","author":"Rosqvist","year":"2014","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib88","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/nm.3092","article-title":"Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy","volume":"19","author":"Rowe","year":"2013","journal-title":"Nature Medicine"},{"issue":"12","key":"10.1016\/bs.ircmb.2025.08.005_bib89","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1080\/15548627.2023.2246357","article-title":"Fatty acid availability controls autophagy and associated cell functions","volume":"19","author":"Rowland","year":"2023","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib90","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1186\/s40001-023-01424-9","article-title":"Crosstalk between autophagy and insulin resistance: evidence from different tissues","volume":"28","author":"Sadeghi","year":"2023","journal-title":"European Journal of Medical Research"},{"issue":"Pt 4","key":"10.1016\/bs.ircmb.2025.08.005_bib91","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1242\/jcs.050377","article-title":"The primary cilium at a glance","volume":"123","author":"Satir","year":"2010","journal-title":"Journal of Cell Science"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib92","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1146\/annurev.cellbio.19.111401.091318","article-title":"Intraflagellar transport","volume":"19","author":"Scholey","year":"2003","journal-title":"Annual Review of Cell and Developmental Biology"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib93","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1083\/jcb.200709133","article-title":"Intraflagellar transport motors in cilia: Moving along the cell\u2019s antenna","volume":"180","author":"Scholey","year":"2008","journal-title":"The Journal of Cell Biology"},{"issue":"1 Pt 2","key":"10.1016\/bs.ircmb.2025.08.005_bib94","first-page":"F132","article-title":"Analysis and modeling of the primary cilium bending response to fluid shear","volume":"272","author":"Schwartz","year":"1997","journal-title":"The American Journal of Physiology"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib95","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.nut.2018.02.018","article-title":"Saturated fatty acids promote chondrocyte matrix remodeling through reprogramming of autophagy pathways","volume":"54","author":"Sekar","year":"2018","journal-title":"Nutrition (Burbank, Los Angeles County, Calif.)"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib96","doi-asserted-by":"crossref","first-page":"327","DOI":"10.4062\/biomolther.2015.025","article-title":"Autophagy regulates formation of primary cilia in Mefloquine-Treated cells","volume":"23","author":"Shin","year":"2015","journal-title":"Biomolecules and Therapeutics (Seoul)"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib97","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/568671","article-title":"The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53","volume":"2013","author":"Shin","year":"2013","journal-title":"BioMed Research International"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib98","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1083\/jcb.200907014","article-title":"Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes","volume":"186","author":"Simonsen","year":"2009","journal-title":"The Journal of Cell Biology"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib99","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1016\/j.celrep.2018.08.005","article-title":"Differential HDAC6 activity modulates ciliogenesis and subsequent mechanosensing of endothelial cells derived from pluripotent stem cells","volume":"24","author":"Smith","year":"2018","journal-title":"Cell Reports"},{"issue":"12","key":"10.1016\/bs.ircmb.2025.08.005_bib100","doi-asserted-by":"crossref","DOI":"10.3390\/genes13122370","article-title":"Proteomic and transcriptomic landscapes of alstrom and Bardet-Biedl syndromes","volume":"13","author":"Smyczynska","year":"2022","journal-title":"Genes (Basel)"},{"issue":"3","key":"10.1016\/bs.ircmb.2025.08.005_bib101","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/s42255-023-00754-6","article-title":"Primary cilia sense glutamine availability and respond via asparagine synthetase","volume":"5","author":"Steidl","year":"2023","journal-title":"Nature Metabolism"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib102","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms13586","article-title":"A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi","volume":"7","author":"Stoetzel","year":"2016","journal-title":"Nature Communications"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib103","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1080\/15548627.2018.1429874","article-title":"The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts","volume":"14","author":"Struchtrup","year":"2018","journal-title":"Autophagy"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib104","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.100488","article-title":"Rab8 attenuates wnt signaling and is required for mesenchymal differentiation into adipocytes","volume":"296","author":"Stypulkowski","year":"2021","journal-title":"The Journal of Biological Chemistry"},{"issue":"38","key":"10.1016\/bs.ircmb.2025.08.005_bib105","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ade4450","article-title":"Sugar, sugar: Glucose activates motion in pancreatic cilia","volume":"8","author":"Sui","year":"2022","journal-title":"Science Advances"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib106","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.208769","article-title":"Glucose deprivation induces primary cilium formation through mTORC1 inactivation","volume":"131","author":"Takahashi","year":"2018","journal-title":"Journal of Cell Science"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib107","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/s41467-017-00369-y","article-title":"Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation","volume":"8","author":"Tan","year":"2017","journal-title":"Nature Communications"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib108","doi-asserted-by":"crossref","first-page":"8273","DOI":"10.1038\/s41467-024-52621-x","article-title":"Lipid droplets sequester palmitic acid to disrupt endothelial ciliation and exacerbate atherosclerosis in Male mice","volume":"15","author":"Tan","year":"2024","journal-title":"Nature Communications"},{"issue":"7470","key":"10.1016\/bs.ircmb.2025.08.005_bib109","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/nature12606","article-title":"Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites","volume":"502","author":"Tang","year":"2013","journal-title":"Nature"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib110","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s11926-019-0822-0","article-title":"The primary cilium: Emerging role as a key player in fibrosis","volume":"21","author":"Teves","year":"2019","journal-title":"Current Rheumatology Reports"},{"issue":"10","key":"10.1016\/bs.ircmb.2025.08.005_bib111","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1177\/088307389901401001","article-title":"Ocular and oculomotor signs in joubert syndrome","volume":"14","author":"Tusa","year":"1999","journal-title":"Journal of Child Neurology"},{"issue":"3","key":"10.1016\/bs.ircmb.2025.08.005_bib112","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/s41580-022-00542-2","article-title":"The mechanisms and roles of selective autophagy in mammals","volume":"24","author":"Vargas","year":"2023","journal-title":"Nature Reviews. Molecular Cell Biology"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib113","doi-asserted-by":"crossref","first-page":"8","DOI":"10.4103\/jomfp.JOMFP_48_17","article-title":"Primary cilia","volume":"21","author":"Venkatesh","year":"2017","journal-title":"Journal of Oral and Maxillofacial Pathology"},{"issue":"14","key":"10.1016\/bs.ircmb.2025.08.005_bib114","doi-asserted-by":"crossref","first-page":"3339","DOI":"10.1002\/j.1460-2075.1995.tb07340.x","article-title":"A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system","volume":"14","author":"Volinia","year":"1995","journal-title":"The EMBO Journal"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib115","doi-asserted-by":"crossref","first-page":"5686","DOI":"10.1038\/s41467-019-12953-5","article-title":"Glucose homeostasis is regulated by pancreatic beta-cell cilia via endosomal EphA-processing","volume":"10","author":"Volta","year":"2019","journal-title":"Nature Communications"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib116","first-page":"100","article-title":"Hsp90alpha forms a stable complex at the cilium neck for the interaction of signalling molecules in IGF-1 receptor signalling","volume":"128","author":"Wang","year":"2015","journal-title":"Journal of Cell Science"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib117","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.jfma.2021.09.003","article-title":"Eye motor manifestations in children with neurometabolic disorders","volume":"121","author":"Wang","year":"2022","journal-title":"Journal of the Formosan Medical Association = Taiwan yi zhi"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib118","article-title":"The miR-669a-5p\/G3BP\/HDAC6\/AKAP12 axis regulates primary cilia length","volume":"11","author":"Wang","year":"2024","journal-title":"Advanced Science (Weinh)"},{"issue":"2","key":"10.1016\/bs.ircmb.2025.08.005_bib119","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1080\/15548627.2020.1725381","article-title":"Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin in fl ammation","volume":"17","author":"Wang","year":"2021","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib120","doi-asserted-by":"crossref","first-page":"i27","DOI":"10.1093\/ckj\/sfy089","article-title":"Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease","volume":"11","author":"Weimbs","year":"2018","journal-title":"Clinical Kidney Journal"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib121","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1006\/cbir.1996.0011","article-title":"Expression of primary cilia in mammalian cells","volume":"20","author":"Wheatley","year":"1996","journal-title":"Cell Biology International"},{"issue":"10","key":"10.1016\/bs.ircmb.2025.08.005_bib122","doi-asserted-by":"crossref","DOI":"10.15252\/embj.201797791","article-title":"Cell type-specific regulation of ciliary transition zone assembly in vertebrates","volume":"37","author":"Wiegering","year":"2018","journal-title":"The EMBO Journal"},{"issue":"6","key":"10.1016\/bs.ircmb.2025.08.005_bib123","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0097957","article-title":"Omega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-kappaB activation and enhancing autophagy","volume":"9","author":"Williams-Bey","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/bs.ircmb.2025.08.005_bib124","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.lfs.2019.01.001","article-title":"Primary cilia and autophagy interaction is involved in mechanical stress mediated cartilage development via ERK\/mTOR axis","volume":"218","author":"Xiang","year":"2019","journal-title":"Life Sciences"},{"issue":"2","key":"10.1016\/bs.ircmb.2025.08.005_bib125","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1080\/15548627.2022.2062112","article-title":"Acetylation in the regulation of autophagy","volume":"19","author":"Xu","year":"2023","journal-title":"Autophagy"},{"issue":"10","key":"10.1016\/bs.ircmb.2025.08.005_bib126","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.108817","article-title":"Primary cilia-dependent lipid raft\/caveolin dynamics regulate adipogenesis","volume":"34","author":"Yamakawa","year":"2021","journal-title":"Cell Reports"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib127","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1038\/s12276-021-00644-5","article-title":"Hypothalamic primary cilium: a hub for metabolic homeostasis","volume":"53","author":"Yang","year":"2021","journal-title":"Experimental & Molecular Medicine"},{"issue":"4","key":"10.1016\/bs.ircmb.2025.08.005_bib128","doi-asserted-by":"crossref","first-page":"932","DOI":"10.3892\/ijmm.2015.2085","article-title":"Palmitate induces endoplasmic reticulum stress and autophagy in mature adipocytes: implications for apoptosis and inflammation","volume":"35","author":"Yin","year":"2015","journal-title":"International Journal of Molecular Medicine"},{"issue":"12","key":"10.1016\/bs.ircmb.2025.08.005_bib129","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1177\/0022034516652383","article-title":"Primary cilia and intraflagellar transport proteins in bone and cartilage","volume":"95","author":"Yuan","year":"2016","journal-title":"Journal of Dental Research"},{"issue":"1","key":"10.1016\/bs.ircmb.2025.08.005_bib130","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/s42003-024-06000-3","article-title":"Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMPKalpha lactylation in intervertebral disc degeneration","volume":"7","author":"Zhang","year":"2024","journal-title":"Communications Biology"},{"issue":"7","key":"10.1016\/bs.ircmb.2025.08.005_bib131","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2019.118641","article-title":"Intraflagellar transport 20: New target for the treatment of ciliopathies","volume":"1867","author":"Zhou","year":"2020","journal-title":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"},{"issue":"Pt 15","key":"10.1016\/bs.ircmb.2025.08.005_bib132","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1242\/jcs.046276","article-title":"Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes","volume":"122","author":"Zhu","year":"2009","journal-title":"Journal of Cell Science"}],"container-title":["International Review of Cell and Molecular Biology","Autophagy - Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193764482500111X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193764482500111X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:36:16Z","timestamp":1781105776000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S193764482500111X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"ISBN":["9780443414251"],"references-count":132,"URL":"https:\/\/doi.org\/10.1016\/bs.ircmb.2025.08.005","relation":{},"ISSN":["1937-6448"],"issn-type":[{"value":"1937-6448","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]}}}