{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:07:28Z","timestamp":1790096848734,"version":"4.0.1"},"reference-count":138,"publisher":"Elsevier","isbn-type":[{"value":"9780443414374","type":"print"}],"license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["CNS2024\\u2013154954"],"award-info":[{"award-number":["CNS2024\\u2013154954"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["PID2021\\u2013127534OB-I00"],"award-info":[{"award-number":["PID2021\\u2013127534OB-I00"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["PID2023\\u2013151873OB-I00"],"award-info":[{"award-number":["PID2023\\u2013151873OB-I00"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["RYC2018\\u2013024434-I"],"award-info":[{"award-number":["RYC2018\\u2013024434-I"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["MINECO PID2023\\u2013151873OB-I00"],"award-info":[{"award-number":["MINECO PID2023\\u2013151873OB-I00"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008054","name":"Fundaci\u00f3n Ram\u00f3n Areces","doi-asserted-by":"publisher","award":["RYC2021\\u2013032836-I"],"award-info":[{"award-number":["RYC2021\\u2013032836-I"]}],"id":[{"id":"10.13039\/100008054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/bs.ircmb.2026.07.006","type":"book-chapter","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:37:09Z","timestamp":1788262629000},"page":"213-273","source":"Crossref","is-referenced-by-count":0,"title":["Sex matters in macroautophagy: Sex-driven differences in autophagic function in aging and aging related-diseases"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7693-0373","authenticated-orcid":false,"given":"Jos\u00e9 Ignacio","family":"Garc\u00eda-Mu\u00f1oz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8446-0212","authenticated-orcid":false,"given":"Alicia","family":"Domenech-Benda\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1736-273X","authenticated-orcid":false,"given":"Lucia","family":"Gimeno-Mallench","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0727-3697","authenticated-orcid":false,"given":"Alejandro","family":"Ponce-Mora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7704-4285","authenticated-orcid":false,"given":"\u00c1lvaro F.","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7672-7335","authenticated-orcid":false,"given":"Daniel","family":"L\u00f3pez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5515-9604","authenticated-orcid":false,"given":"Jose Luis","family":"Nieto-Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8390-1581","authenticated-orcid":false,"given":"Eloy","family":"Bejarano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/bs.ircmb.2026.07.006_bib1","doi-asserted-by":"crossref","first-page":"R1357","DOI":"10.1016\/j.cub.2022.11.002","article-title":"Orchestration of selective autophagy by cargo receptors","volume":"32","author":"Adriaenssens","year":"2022","journal-title":"Current Biology: CB"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib2","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1080\/27694127.2022.2062965","article-title":"DRAMs and autophagy: A family affair","volume":"1","author":"Barthet","year":"2022","journal-title":"Autophagy Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2021.119064","article-title":"Small but mighty: Atg8s and Rabs in membrane dynamics during autophagy","volume":"1868","author":"Barz","year":"2021","journal-title":"Biochimica et Biophysica Acta. Molecular Cell Research"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib4","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.neurobiolaging.2023.05.015","article-title":"Sex differences in socioemotional behavior and changes in ventral hippocampal transcription across aging in C57Bl\/6J mice","volume":"130","author":"Baumgartner","year":"2023","journal-title":"Neurobiology of Aging"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1513\/pats.200909-102JS","article-title":"Chaperone-mediated autophagy","volume":"7","author":"Bejarano","year":"2010","journal-title":"Proceedings of the American Thoracic Society"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib6","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12777","article-title":"Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging","volume":"17","author":"Bejarano","year":"2018","journal-title":"Aging Cell"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib7","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1016\/j.tjnut.2023.02.035","article-title":"Modifying dietary protein impacts mTOR signaling and brain deposition of amyloid \u03b2 in a knock-in mouse model of Alzheimer disease","volume":"153","author":"Bensalem","year":"2023","journal-title":"The Journal of Nutrition"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib8","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1113\/JP287938","article-title":"Intermittent time-restricted eating may increase autophagic flux in humans: An exploratory analysis","volume":"603","author":"Bensalem","year":"2025","journal-title":"The Journal of Physiology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib9","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3390\/antiox12010077","article-title":"Sex differences in X-ray-induced endothelial damage: Effect of taurine and N-acetylcysteine","volume":"12","author":"Campesi","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib10","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1002\/jcp.30503","article-title":"Human monocytes respond to lipopolysaccharide (LPS) stimulation in a sex-dependent manner","volume":"237","author":"Campesi","year":"2022","journal-title":"Journal of Cellular Physiology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0325505","article-title":"Autophagy across tissues of aging mice","volume":"20","author":"Carosi","year":"2025","journal-title":"PLoS One"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib12","doi-asserted-by":"crossref","first-page":"11544","DOI":"10.3390\/ijms241411544","article-title":"Gender differences and miRNAs expression in cancer: Implications on prognosis and susceptibility","volume":"24","author":"Caserta","year":"2023","journal-title":"International Journal of Molecular Sciences"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib13","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.tem.2019.07.009","article-title":"The foxO-autophagy axis in health and disease","volume":"30","author":"Cheng","year":"2019","journal-title":"Trends in Endocrinology and Metabolism: TEM"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib14","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3390\/cells9020325","article-title":"Polyglutamine-expanded androgen receptor alteration of skeletal muscle homeostasis and myonuclear aggregation are affected by sex, age and muscle metabolism","volume":"9","author":"Chivet","year":"2020","journal-title":"Cells"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2023.101918","article-title":"Sex difference in biological change and mechanism of Alzheimer\u2019s disease: From macro- to micro-landscape","volume":"87","author":"Cui","year":"2023","journal-title":"Ageing Research Reviews"},{"issue":"22","key":"10.1016\/bs.ircmb.2026.07.006_bib16","doi-asserted-by":"crossref","first-page":"4436","DOI":"10.1016\/j.molcel.2024.10.022","article-title":"VPS4A is the selective receptor for lipophagy in mice and humans","volume":"84","author":"Das","year":"2024","journal-title":"Molecular Cell"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib17","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.3390\/cells13151247","article-title":"Sex differences affect the NRF2 signaling pathway in the early phase of liver steatosis: A high-fat-diet-fed rat model supplemented with liquid fructose","volume":"13","author":"Di Veroli","year":"2024","journal-title":"Cells"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib18","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/s41467-019-14164-4","article-title":"Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo","volume":"11","author":"Dong","year":"2020","journal-title":"Nature Communications"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib19","article-title":"Identification of sex-specific biomarkers related to programmed cell death and analysis of immune cells in ankylosing spondylitis","volume":"14","author":"Dong","year":"2024","journal-title":"Scientific Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib20","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1080\/15548627.2020.1725378","article-title":"Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy","volume":"17","author":"Endicott","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib21","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12876","article-title":"Autophagy and aging: Maintaining the proteome through exercise and caloric restriction","volume":"18","author":"Escobar","year":"2019","journal-title":"Aging Cell"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.hnm.2020.200118","article-title":"Autophagy response to acute high-intensity interval training and moderate-intensity continuous training is dissimilar in skeletal muscle and peripheral blood mononuclear cells and is influenced by sex","volume":"23","author":"Escobar","year":"2021","journal-title":"Human Nutrition & Metabolism"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1172\/JCI73940","article-title":"The functional and pathologic relevance of autophagy proteases","volume":"125","author":"Fern\u00e1ndez","year":"2015","journal-title":"The Journal of Clinical Investigation"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib24","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/s41586-018-0162-7","article-title":"Disruption of the beclin 1\u2013BCL2 autophagy regulatory complex promotes longevity in mice","volume":"558","author":"Fern\u00e1ndez","year":"2018","journal-title":"Nature"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib25","doi-asserted-by":"crossref","first-page":"14929","DOI":"10.3390\/ijms241914929","article-title":"Sex influence on autophagy markers and miRNAs in basal and angiotensin II-treated human umbilical vein endothelial cells","volume":"24","author":"Franconi","year":"2023","journal-title":"International Journal of Molecular Sciences"},{"issue":"1","key":"10.1016\/bs.ircmb.2026.07.006_bib26","doi-asserted-by":"crossref","first-page":"18597","DOI":"10.1038\/s41598-019-54743-5","article-title":"Selective autophagy, lipophagy and mitophagy, in the Harderian gland along the oestrous cycle: a potential retrieval effect of melatonin","volume":"9","author":"Garc\u00eda-Macia","year":"2019","journal-title":"Scientific Reports"},{"issue":"6","key":"10.1016\/bs.ircmb.2026.07.006_bib27","doi-asserted-by":"crossref","first-page":"3441","DOI":"10.1002\/hep.32048","article-title":"A mammalian target of rapamycin-perilipin 3 (mTORC1-Plin3) pathway is essential to activate lipophagy and protects against hepatosteatosis","volume":"74","author":"Garcia-Macia","year":"2021","journal-title":"Hepatology (Baltimore, Md.)"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib28","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.15252\/embj.201796697","article-title":"Molecular definitions of autophagy and related processes","volume":"36","author":"Galluzzi","year":"2017","journal-title":"The EMBO Journal"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2024.101971","article-title":"Sphingosine kinase 2 and p62 regulation are determinants of sexual dimorphism in hepatocellular carcinoma","volume":"86","author":"Green","year":"2024","journal-title":"Molecular Metabolism"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib30","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.63425","article-title":"Sex differences in biological aging with a focus on human studies","volume":"10","author":"H\u00e4gg","year":"2021","journal-title":"eLife"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib31","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/s41580-018-0033-y","article-title":"Autophagy as a promoter of longevity: Insights from model organisms","volume":"19","author":"Hansen","year":"2018","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib32","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.2174\/1389557522666220914093331","article-title":"The role of gut microbiota in inflammatory bowel disease-current state of the art","volume":"23","author":"Hassan","year":"2023","journal-title":"Mini-Reviews in Medicinal Chemistry"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib33","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1146\/annurev-biochem-061516-044820","article-title":"Mechanisms of autophagy initiation","volume":"86","author":"Hurley","year":"2017","journal-title":"Annual Review of Biochemistry"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.cophys.2022.100597","article-title":"Chaperone-mediated autophagy: Mechanisms and physiological relevance","volume":"30","author":"Jafari","year":"2022","journal-title":"Current Opinion in Physiology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib35","doi-asserted-by":"crossref","DOI":"10.3390\/cells10112814","article-title":"Key regulators of autophagosome closure","volume":"10","author":"Jiang","year":"2021","journal-title":"Cells"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib36","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jmb.2019.07.016","article-title":"Selective autophagy: ATG8 family proteins, LIR motifs and cargo receptors","volume":"432","author":"Johansen","year":"2020","journal-title":"Journal of Molecular Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2024.111021","article-title":"Social-single prolonged stress affects contextual fear conditioning in male and female Wistar rats: Molecular insights in the amygdala","volume":"133","author":"Jung","year":"2024","journal-title":"Progress in Neuro-Psychopharmacology and Biological Psychiatry"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib38","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.biopsych.2021.09.018","article-title":"Novel ADNP syndrome mice reveal dramatic sex-specific peripheral gene expression with brain synaptic and tau pathologies","volume":"92","author":"Karmon","year":"2022","journal-title":"Biological Psychiatry"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib39","doi-asserted-by":"crossref","first-page":"R318","DOI":"10.1016\/j.cub.2017.02.061","article-title":"The cytoskeleton-autophagy connection","volume":"27","author":"Kast","year":"2017","journal-title":"Current Biology: CB"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib40","article-title":"Sex differences in heart failure with preserved ejection fraction: From traditional risk factors to sex-specific risk factors","volume":"18","author":"Kaur","year":"2022","journal-title":"Women\u2019s Health"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib41","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/s41580-018-0001-6","article-title":"The coming of age of chaperone-mediated autophagy","volume":"19","author":"Kaushik","year":"2018","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib42","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.1038\/sj.emboj.7601283","article-title":"Lysosome membrane lipid microdomains: Novel regulators of chaperone\u2010mediated autophagy","volume":"25","author":"Kaushik","year":"2006","journal-title":"The EMBO Journal"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib43","doi-asserted-by":"crossref","DOI":"10.1172\/JCI172890","article-title":"Mouse sarcopenia model reveals sex- and age-specific differences in phenotypic and molecular characteristics","volume":"134","author":"Kerr","year":"2024","journal-title":"The Journal of Clinical Investigation"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib44","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1038\/s43587-024-00799-6","article-title":"Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging","volume":"5","author":"Khawaja","year":"2025","journal-title":"Nature Aging"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib45","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1242\/jcs.001073","article-title":"Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age","volume":"120","author":"Kiffin","year":"2007","journal-title":"Journal of Cell Science"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2021.108769","article-title":"PAR2 promotes high-fat diet-induced hepatic steatosis by inhibiting AMPK-mediated autophagy","volume":"95","author":"Kim","year":"2021","journal-title":"The Journal of Nutritional Biochemistry"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2024.102229","article-title":"Autophagy activation in response to cigarette smoke: Exploring the disparity in laryngeal cancer incidence and outcomes between sexes in South Korea","volume":"52","author":"Kim","year":"2025","journal-title":"Translational Oncology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpb.2020.110547","article-title":"Change on apoptosis, autophagy and mitochondria of the Harderian gland in Cricetulus barabensis during age","volume":"253","author":"Kong","year":"2021","journal-title":"Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib49","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.cub.2010.04.041","article-title":"DAP1, a novel substrate of mTOR, negatively regulates autophagy","volume":"20","author":"Koren","year":"2010","journal-title":"Current Biology: CB"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib50","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13713","article-title":"Reduced endosomal microautophagy activity in aging associates with enhanced exocyst-mediated protein secretion","volume":"21","author":"Krause","year":"2022","journal-title":"Aging Cell"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.113529","article-title":"Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy","volume":"42","author":"Krause","year":"2023","journal-title":"Cell Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib52","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.tcb.2023.11.005","article-title":"Lysosomal microautophagy: An emerging dimension in mammalian autophagy","volume":"34","author":"Kuchitsu","year":"2024","journal-title":"Trends in Cell Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib53","doi-asserted-by":"crossref","first-page":"5545","DOI":"10.1038\/s41598-021-85127-3","article-title":"Antioxidants, lysosomes and elements status during the life cycle of sea trout Salmo trutta m. trutta L","volume":"11","author":"Kurhaluk","year":"2021","journal-title":"Scientific Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib54","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1146\/annurev-cellbio-120219-035530","article-title":"Mechanisms of selective autophagy","volume":"37","author":"Lamark","year":"2021","journal-title":"Annual Review of Cell and Developmental Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib55","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1042\/EBC20170035","article-title":"Regulation of selective autophagy: The p62\/SQSTM1 paradigm","volume":"61","author":"Lamark","year":"2017","journal-title":"Essays in Biochemistry"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib56","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1038\/ncomms3267","article-title":"The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans","volume":"4","author":"Lapierre","year":"2013","journal-title":"Nature Communications"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib57","article-title":"Chaperone-mediated autophagy reactivation protects against severe acute pancreatitis-associated liver injury through upregulating keap1\/Nrf2 signaling pathway and inhibiting NLRP3 inflammasome activation","author":"Li","year":"2025","journal-title":"Cell Biochemistry and Biophysics"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib58","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/8096847","article-title":"Gender difference on the effect of omega-3 polyunsaturated fatty acids on acetaminophen-induced acute liver failure","volume":"2020","author":"Liu","year":"2020","journal-title":"Oxidative Medicine and Cellular Longevity"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib59","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.3389\/fgene.2021.742704","article-title":"Maternal overnutrition during gestation in sheep alters autophagy associated pathways in offspring heart","volume":"12","author":"Liu","year":"2022","journal-title":"Frontiers in Genetics"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib60","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s13293-022-00477-5","article-title":"Unveiling sex-based differences in Parkinson\u2019s disease: a comprehensive meta-analysis of transcriptomic studies","volume":"13","author":"L\u00f3pez-Cerd\u00e1n","year":"2022","journal-title":"Biology of Sex Differences"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib61","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.neuron.2024.01.024","article-title":"Mechanisms of sex differences in Alzheimer\u2019s disease","volume":"112","author":"Lopez-Lee","year":"2024","journal-title":"Neuron"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib62","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.cell.2013.05.039","article-title":"The hallmarks of aging","volume":"153","author":"L\u00f3pez-Ot\u00edn","year":"2013","journal-title":"Cell"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib63","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.cell.2022.11.001","article-title":"Hallmarks of aging: An expanding universe","volume":"186","author":"L\u00f3pez-Ot\u00edn","year":"2023","journal-title":"Cell"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib64","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1010626","article-title":"Fish female-biased gene cyp19a1a leads to female antiviral response attenuation between sexes by autophagic degradation of MITA","volume":"18","author":"Lu","year":"2022","journal-title":"PLoS Pathogens"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.acthis.2021.151817","article-title":"Sex-specific effects of metformin and liraglutide on renal pathology and expression of connexin 45 and pannexin 1 following long-term high-fat high-sugar diet","volume":"123","author":"Lueti\u0107","year":"2021","journal-title":"Acta Histochemica"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib66","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.3389\/fphys.2021.752347","article-title":"Differential autophagy response in men and women after muscle damage","volume":"12","author":"Luk","year":"2021","journal-title":"Frontiers in Physiology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib67","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1080\/15548627.2025.2489530","article-title":"Unraveling the complexity of chaperone-mediated autophagy in aging: Insights into sex-specific and cell-type-specific regulation","volume":"21","author":"Luo","year":"2025","journal-title":"Autophagy"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib68","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2121133119","article-title":"Protective role of chaperone-mediated autophagy against atherosclerosis","volume":"119","author":"Madrigal-Matute","year":"2022","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib69","doi-asserted-by":"crossref","DOI":"10.4103\/AGINGADV.AGINGADV-D-24-00002","article-title":"Selective autophagy: A therapeutic target for healthy aging?","volume":"1","author":"Manastireanu","year":"2024","journal-title":"Aging Advances"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib70","doi-asserted-by":"crossref","first-page":"15153","DOI":"10.3390\/ijms242015153","article-title":"Small molecule pytren-4QMn metal complex slows down Huntington\u2019s disease progression in male zQ175 transgenic mice","volume":"24","author":"Merino","year":"2023","journal-title":"International Journal of Molecular Sciences"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib71","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ceb.2019.12.001","article-title":"The ATG conjugation systems in autophagy","volume":"63","author":"Mizushima","year":"2020","journal-title":"Current Opinion in Cell Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib72","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.freeradbiomed.2024.09.028","article-title":"Regulation of lysosomes in skeletal muscle during exercise, disuse and aging","volume":"225","author":"Moradi","year":"2024","journal-title":"Free Radical Biology and Medicine"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib73","article-title":"Monitoring autophagy in human aging: Key cell models and insights","volume":"30","author":"Moreno","year":"2025","journal-title":"FBL"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib74","doi-asserted-by":"crossref","first-page":"H785","DOI":"10.1152\/ajpheart.00644.2021","article-title":"Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus specific","volume":"322","author":"Muehleman","year":"2022","journal-title":"American Journal of Physiology-Heart and Circulatory Physiology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib75","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.ijpara.2020.11.011","article-title":"First insights into the autophagy machinery of adult Schistosoma mansoni","volume":"51","author":"Mughal","year":"2021","journal-title":"International Journal for Parasitology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib76","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/s41580-020-0241-0","article-title":"Mechanisms governing autophagosome biogenesis","volume":"21","author":"Nakatogawa","year":"2020","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib77","series-title":"Human reproductive and prenatal genetics","first-page":"355","article-title":"Chapter 14 - Human X-chromosome inactivation: Complexity and clinical implications","author":"Navarro-Cobos","year":"2023"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2021.101020","article-title":"Macroautophagy and aging: The impact of cellular recycling on health and longevity","volume":"82","author":"Nieto-Torres","year":"2021","journal-title":"Molecular Aspects of Medicine"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib79","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/j.cub.2021.05.052","article-title":"LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes","volume":"31","author":"Nieto-Torres","year":"2021","journal-title":"Current Biology: CB"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib80","article-title":"Atg2 and Atg9: Intermembrane and interleaflet lipid transporters driving autophagy","volume":"1866","author":"Noda","year":"2021","journal-title":"Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib81","doi-asserted-by":"crossref","DOI":"10.1080\/27694127.2023.2277582","article-title":"Structural biology of the Atg8 and Atg12 conjugation systems","volume":"2","author":"Noda","year":"2023","journal-title":"Autophagy Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib82","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/1873-3468.14742","article-title":"Structural view on autophagosome formation","volume":"598","author":"Noda","year":"2024","journal-title":"FEBS Letters"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib83","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/1673-5374.340406","article-title":"Sex-biased autophagy as a potential mechanism mediating sex differences in ischemic stroke outcome","volume":"18","author":"Noh","year":"2023","journal-title":"Neural Regeneration Research"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib84","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202357300","article-title":"Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging","volume":"24","author":"Ogura","year":"2023","journal-title":"EMBO Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib85","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13395-024-00339-1","article-title":"Dimorphic effect of TFE3 in determining mitochondrial and lysosomal content in muscle following denervation","volume":"14","author":"Oliveira","year":"2024","journal-title":"Skeletal Muscle"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib86","doi-asserted-by":"crossref","first-page":"993","DOI":"10.3390\/biology12070993","article-title":"The role of sex differences in bone health and healing","volume":"12","author":"Ortona","year":"2023","journal-title":"Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib87","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.3390\/cells10071825","article-title":"Sex-specific differences in autophagic responses to experimental ischemic stroke","volume":"10","author":"Patrizz","year":"2021","journal-title":"Cells"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib88","article-title":"Interplay between polyphenols and autophagy: Insights from an aging perspective","volume":"30","author":"Ponce-Mora","year":"2025","journal-title":"Frontiers in Bioscience (Landmark edition)"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib89","doi-asserted-by":"crossref","DOI":"10.1002\/arch.21719","article-title":"Comprehensive analysis of differentially expressed proteins in the male and female Bombyx mori larval instars exposed to thermal stress","volume":"105","author":"Punyavathi","year":"2020","journal-title":"Archives of Insect Biochemistry and Physiology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib90","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1038\/ncomms3300","article-title":"Overexpression of Atg5 in mice activates autophagy and extends lifespan","volume":"4","author":"Pyo","year":"2013","journal-title":"Nature Communications"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib91","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.244282","article-title":"Reproductive tradeoffs govern sexually dimorphic tubular lysosome induction in Caenorhabditis elegans","volume":"225","author":"Ramos","year":"2022","journal-title":"Journal of Experimental Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib92","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2023.1166125","article-title":"Lost in traffic: Consequences of altered palmitoylation in neurodegeneration","volume":"14","author":"Ramzan","year":"2023","journal-title":"Frontiers in Physiology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib93","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1038\/s43587-022-00308-7","article-title":"Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin","volume":"2","author":"Regan","year":"2022","journal-title":"Nature Aging"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib94","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2322929121","article-title":"Restoration of LAMP2A expression in old mice leads to changes in the T cell compartment that support improved immune function","volume":"121","author":"Reynolds","year":"2024","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib95","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.3389\/fcvm.2024.1298014","article-title":"Trehalose promotes atherosclerosis regression in female mice","volume":"11","author":"Robichaud","year":"2024","journal-title":"Frontiers in Cardiovascular Medicine"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib96","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1002\/jcsm.12809","article-title":"Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice","volume":"12","author":"Rosa-Caldwell","year":"2021","journal-title":"Journal of Cachexia, Sarcopenia and Muscle"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib97","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/1873-3468.14760","article-title":"ATG and ESCRT control multiple modes of microautophagy","volume":"598","author":"Sakai","year":"2024","journal-title":"FEBS Letters"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib98","article-title":"Chaperone-mediated autophagy sustains pericyte stemness necessary for brain tissue homeostasis","author":"Salinas","year":"2025","journal-title":"Journal of Advanced Research"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib99","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3390\/ijms26010192","article-title":"Expression of lumican and osteopontin in perivascular areas of the glioblastoma peritumoral niche and its value for prognosis","volume":"26","author":"Salinas","year":"2025","journal-title":"International Journal of Molecular Sciences"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib100","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.3389\/fnagi.2022.1009368","article-title":"Sex-specific transcriptional rewiring in the brain of Alzheimer\u2019s disease patients","volume":"14","author":"Santiago","year":"2022","journal-title":"Frontiers in Aging Neuroscience"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib101","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1126\/science.1204592","article-title":"TFEB links autophagy to lysosomal biogenesis","volume":"332","author":"Settembre","year":"2011","journal-title":"Science (New York, N. Y.)"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib102","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1080\/15548627.2020.1752511","article-title":"Sex differences in autophagy-mediated diseases: Toward precision medicine","volume":"17","author":"Shang","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib103","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/1873-3468.14679","article-title":"Autophagy in a nutshell","volume":"598","author":"Shatz","year":"2024","journal-title":"FEBS Letters"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib104","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.3389\/fnmol.2021.661993","article-title":"Neonatal maternal separation modifies proteostasis marker expression in the adult hippocampus","volume":"14","author":"Sierra-Fonseca","year":"2021","journal-title":"Frontiers in Molecular Neuroscience"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib105","doi-asserted-by":"crossref","first-page":"176","DOI":"10.4161\/auto.5269","article-title":"Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila","volume":"4","author":"Simonsen","year":"2008","journal-title":"Autophagy"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib106","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.831879","article-title":"Hepatic PPAR\u03b1 is destabilized by SIRT1 deacetylase in undernourished male mice","volume":"9","author":"Suh","year":"2022","journal-title":"Frontiers in Nutrition"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib107","doi-asserted-by":"crossref","first-page":"577","DOI":"10.3390\/ijerph18020577","article-title":"Sex-specific alterations in cardiac DNA methylation in adult mice by perinatal lead exposure","volume":"18","author":"Svoboda","year":"2021","journal-title":"International Journal of Environmental Research and Public Health"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib108","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2024.114293","article-title":"Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females","volume":"43","author":"Tam","year":"2024","journal-title":"Cell Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib109","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19123812","article-title":"AMPK: Regulation of metabolic dynamics in the context of autophagy","volume":"19","author":"Tamargo-G\u00f3mez","year":"2018","journal-title":"International Journal of Molecular Sciences"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib110","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/s41420-021-00438-8","article-title":"Sirt1 coordinates with ER\u03b1 to regulate autophagy and adiposity","volume":"7","author":"Tao","year":"2021","journal-title":"Cell Death Discovery"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib111","doi-asserted-by":"crossref","first-page":"5414","DOI":"10.1074\/jbc.R117.818237","article-title":"Chaperone-mediated autophagy and endosomal microautophagy: Jointed by a chaperone","volume":"293","author":"Tekirdag","year":"2018","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib112","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2020.115261","article-title":"Resveratrol ameliorates lipopolysaccharide-induced anxiety-like behavior by attenuating YAP-mediated neuro-inflammation and promoting hippocampal autophagy in mice","volume":"408","author":"Tian","year":"2020","journal-title":"Toxicology and Applied Pharmacology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib113","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1156583","article-title":"From mitochondria to sarcopenia: Role of 17\u03b2-estradiol and testosterone","volume":"14","author":"Tian","year":"2023","journal-title":"Frontiers in Endocrinology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib114","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1080\/15548627.2020.1823124","article-title":"New insights regarding SNARE proteins in autophagosome-lysosome fusion","volume":"17","author":"Tian","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib115","doi-asserted-by":"crossref","first-page":"4535","DOI":"10.3390\/nu14214535","article-title":"Sex specific differences in response to calorie restriction in skeletal muscle of young rats","volume":"14","author":"Torrens-Mas","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib116","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101488","article-title":"Sex differences in the response to oxidative and proteolytic stress","volume":"31","author":"Tower","year":"2020","journal-title":"Redox Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib117","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s13395-022-00296-7","article-title":"The influence of age, sex, and exercise on autophagy, mitophagy, and lysosome biogenesis in skeletal muscle","volume":"12","author":"Triolo","year":"2022","journal-title":"Skeletal Muscle"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib118","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1002\/tox.24427","article-title":"Evaluation of TRPM2 channel-mediated autophagic signaling pathway in hippocampus and cortex tissues of rat offspring following prenatal exposure to elevated alcohol levels","volume":"40","author":"U\u011fuz","year":"2025","journal-title":"Environmental Toxicology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib119","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/j.celrep.2014.08.006","article-title":"AMPK modulates tissue and organismal aging in a non-cell-autonomous manner","volume":"8","author":"Ulgherait","year":"2014","journal-title":"Cell Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib120","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1038\/ni.3003","article-title":"Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation","volume":"15","author":"Valdor","year":"2014","journal-title":"Nature Immunology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib121","doi-asserted-by":"crossref","DOI":"10.1016\/j.ceb.2025.102515","article-title":"Trafficking to the lysosome: HOPS paves the way","volume":"94","author":"van der Beek","year":"2025","journal-title":"Current Opinion in Cell Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib122","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/s41580-022-00542-2","article-title":"The mechanisms and roles of selective autophagy in mammals","volume":"24","author":"Vargas","year":"2023","journal-title":"Nature Reviews. Molecular Cell Biology"},{"issue":"7","key":"10.1016\/bs.ircmb.2026.07.006_bib123","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.4161\/auto.5.7.9610","article-title":"Sexual dimorphism of autophagy in Syrian hamster Harderian gland culminates in a holocrine secretion in female glands","volume":"5","author":"Vega-Naredo","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib124","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/s41580-019-0177-4","article-title":"The many functions of ESCRTs","volume":"21","author":"Vietri","year":"2020","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib125","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12950-020-00253-5","article-title":"Offspring sex affects the susceptibility to maternal smoking-induced lung inflammation and the effect of maternal antioxidant supplementation in mice","volume":"17","author":"Wang","year":"2020","journal-title":"Journal of Inflammation"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib126","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.3390\/ijms22052648","article-title":"Current understanding of the involvement of the insular cortex in neuropathic pain: A narrative review","volume":"22","author":"Wang","year":"2021","journal-title":"International Journal of Molecular Sciences"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib127","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.3892\/mmr.2017.6794","article-title":"Hypoxia inducible factor-1\u03b1 regulates autophagy via the p27-E2F1 signaling pathway","volume":"16","author":"Wang","year":"2017","journal-title":"Molecular Medicine Reports"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib128","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/978-981-15-0602-4_3","article-title":"Regulation of autophagy by mTOR signaling pathway","volume":"1206","author":"Wang","year":"2019","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib129","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpa.2020.110766","article-title":"Novel ultrastructural findings on cardiac mitochondria of huddling Brandt\u2019s voles in mild cold environment","volume":"249","author":"Wang","year":"2020","journal-title":"Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib130","doi-asserted-by":"crossref","first-page":"10850","DOI":"10.1074\/jbc.M109.080796","article-title":"Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase","volume":"285","author":"Wu","year":"2010","journal-title":"The Journal of Biological Chemistry"},{"issue":"2","key":"10.1016\/bs.ircmb.2026.07.006_bib131","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1080\/15548627.2018.1520549","article-title":"How does estrogen work on autophagy?","volume":"15","author":"Xiang","year":"2019","journal-title":"Autophagy"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib132","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/s41421-020-0141-7","article-title":"Lysosome biology in autophagy","volume":"6","author":"Yim","year":"2020","journal-title":"Cell Discovery"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib133","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1042\/EBC20170021","article-title":"The mammalian ULK1 complex and autophagy initiation","volume":"61","author":"Zachari","year":"2017","journal-title":"Essays in Biochemistry"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib134","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0244-24.2024","article-title":"Sex-specific contrasting role of BECLIN-1 protein in pain hypersensitivity and anxiety-like behaviors","volume":"12","author":"Zaheer","year":"2025","journal-title":"eNeuro"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib135","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/nm.1851","article-title":"Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function","volume":"14","author":"Zhang","year":"2008","journal-title":"Nature Medicine"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib136","first-page":"4685","article-title":"LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice","volume":"15","author":"Zhang","year":"2023","journal-title":"Aging"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib137","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/s41580-021-00392-4","article-title":"Machinery, regulation and pathophysiological implications of autophagosome maturation","volume":"22","author":"Zhao","year":"2021","journal-title":"Nature Reviews. Molecular Cell Biology"},{"key":"10.1016\/bs.ircmb.2026.07.006_bib138","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2023.1157398","article-title":"Oxidative stress and inflammation distinctly drive molecular mechanisms of diastolic dysfunction and remodeling in female and male heart failure with preserved ejection fraction rats","volume":"10","author":"Zhazykbayeva","year":"2023","journal-title":"Frontiers in Cardiovascular Medicine"}],"container-title":["International Review of Cell and Molecular Biology","Autophagy \u2013 Part C"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1937644826001061?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1937644826001061?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:10:59Z","timestamp":1790093459000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1937644826001061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"ISBN":["9780443414374"],"references-count":138,"URL":"https:\/\/doi.org\/10.1016\/bs.ircmb.2026.07.006","relation":{},"ISSN":["1937-6448"],"issn-type":[{"value":"1937-6448","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]}}}