{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T02:37:23Z","timestamp":1780367843980,"version":"3.54.1"},"reference-count":155,"publisher":"Elsevier","isbn-type":[{"value":"9780128151419","type":"print"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1016\/bs.irn.2018.08.006","type":"book-chapter","created":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T18:25:17Z","timestamp":1535567117000},"page":"37-65","source":"Crossref","is-referenced-by-count":10,"title":["SPECT Molecular Imaging in Atypical Parkinsonism"],"prefix":"10.1016","author":[{"given":"Joachim","family":"Brumberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis U.","family":"Isaias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/bs.irn.2018.08.006_bb0010","first-page":"1129","article-title":"SPECT imaging of dopamine transporters in human brain with iodine-123-fluoroalkyl analogs of beta-CIT","volume":"37","author":"Abi-Dargham","year":"1996","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0015","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10072-003-0103-5","article-title":"123I-Ioflupane\/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy","volume":"24","author":"Antonini","year":"2003","journal-title":"Neurological Sciences"},{"key":"10.1016\/bs.irn.2018.08.006_bb0020","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1212\/WNL.0b013e31827f0fd1","article-title":"Criteria for the diagnosis of corticobasal degeneration","volume":"80","author":"Armstrong","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0025","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/mds.10106","article-title":"Steele\u2013Richardson\u2013Olszewski-syndrome: Reduction of dopamine D2 receptor binding relates to the severity of midbrain atrophy in vivo: (123)IBZM SPECT and MRI study","volume":"17","author":"Arnold","year":"2002","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0030","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.nicl.2016.07.004","article-title":"Discriminating among degenerative parkinsonisms using advanced (123)I-ioflupane SPECT analyses","volume":"12","author":"Badoud","year":"2016","journal-title":"Neuroimage Clinical"},{"key":"10.1016\/bs.irn.2018.08.006_bb0035","first-page":"1095","article-title":"Quantitative assessment of cerebral blood flow in patients with Alzheimer's disease by SPECT","volume":"38","author":"Bartenstein","year":"1997","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0040","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/S1474-4422(11)70077-1","article-title":"Cerebral amyloid-\u03b2 PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: A multicentre phase 2 diagnostic study","volume":"10","author":"Barthel","year":"2011","journal-title":"Lancet Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0045","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1002\/1531-8257(200005)15:3<503::AID-MDS1013>3.0.CO;2-V","article-title":"Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123 I]-FP-CIT SPECT imaging: The [123 I]-FP-CIT study group","volume":"3","author":"Benamer","year":"2000","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0050","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/(SICI)1098-2396(199711)27:3<183::AID-SYN4>3.0.CO;2-9","article-title":"[123I]FP-CIT binds to the dopamine transporter as assessed by biodistribution studies in rats and SPECT studies in MPTP-lesioned monkeys","volume":"27","author":"Booij","year":"1997","journal-title":"Synapse"},{"key":"10.1016\/bs.irn.2018.08.006_bb0055","first-page":"359","article-title":"Quantification of striatal dopamine transporters with 123I-FP-CIT SPECT is influenced by the selective serotonin reuptake inhibitor paroxetine: A double-blind, placebo-controlled, crossover study in healthy control subjects","volume":"48","author":"Booij","year":"2007","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0060","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1111\/ijcp.12445","article-title":"Combined DaT imaging and olfactory testing for differentiating parkinsonian disorders","volume":"68","author":"Borghammer","year":"2014","journal-title":"International Journal of Clinical Practice"},{"key":"10.1016\/bs.irn.2018.08.006_bb0065","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s00259-002-1009-9","article-title":"Anatomically standardised 99mTc-ECD brain perfusion SPET allows accurate differentiation between healthy volunteers, multiple system atrophy and idiopathic Parkinson's disease","volume":"30","author":"Bosman","year":"2003","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0070","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/978-3-7091-6842-4_2","article-title":"Measurement of the dopaminergic degeneration in Parkinson's disease with [123I] beta-CIT and SPECT. Correlation with clinical findings and comparison with multiple system atrophy and progressive supranuclear palsy","volume":"50","author":"Br\u00fccke","year":"1997","journal-title":"Journal of Neural Transmission. Supplementum"},{"key":"10.1016\/bs.irn.2018.08.006_bb0075","first-page":"1196","article-title":"Iodine-123-IBF SPECT evaluation of extrapyramidal diseases","volume":"36","author":"Buck","year":"1995","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0080","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/mds.20112","article-title":"Impact of dopamine transporter SPECT using 123I-Ioflupane on diagnosis and management of patients with clinically uncertain Parkinsonian syndromes","volume":"19","author":"Catafau","year":"2004","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0085","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/ana.24711","article-title":"In vivo cortical spreading pattern of tau and amyloid in the Alzheimer disease spectrum","volume":"80","author":"Cho","year":"2016","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0090","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1002\/mds.22649","article-title":"MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from parkinsonism-predominant multiple system atrophy","volume":"24","author":"Chung","year":"2009","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0018301","article-title":"Dopamine transporter SPECT imaging in corticobasal syndrome","volume":"6","author":"Cilia","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/bs.irn.2018.08.006_bb0100","doi-asserted-by":"crossref","first-page":"2798","DOI":"10.1093\/brain\/aws211","article-title":"Neuropathological correlates of dopaminergic imaging in Alzheimer's disease and Lewy body dementias","volume":"135","author":"Colloby","year":"2012","journal-title":"Brain"},{"key":"10.1016\/bs.irn.2018.08.006_bb0105","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1007\/BF00833017","article-title":"In vivo characterisation of 3-iodo-6-methoxybenzamide 123I in humans","volume":"16","author":"Costa","year":"1990","journal-title":"European Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0110","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00259-009-1267-x","article-title":"EANM procedure guidelines for brain neurotransmission SPECT using (123)I-labelled dopamine transporter ligands, version 2","volume":"37","author":"Darcourt","year":"2010","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0115","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s12149-014-0878-x","article-title":"Comparison between visual assessment of dopaminergic degeneration pattern and semi-quantitative ratio calculations in patients with Parkinson's disease and atypical Parkinsonian syndromes using DaTSCAN\u00ae SPECT","volume":"28","author":"Davidsson","year":"2014","journal-title":"Annals of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0120","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.coph.2008.12.002","article-title":"Getting specialized: Presynaptic and postsynaptic dopamine D2 receptors","volume":"9","author":"De Mei","year":"2009","journal-title":"Current Opinion in Pharmacology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0125","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0022-510X(00)00279-3","article-title":"Differentiation of Parkinson's disease and multiple system atrophy in early disease stages by means of I-123-MIBG-SPECT","volume":"175","author":"Druschky","year":"2000","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/bs.irn.2018.08.006_bb0130","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00259-005-1920-y","article-title":"Quantitative simultaneous (99m)Tc-ECD\/123I-FP-CIT SPECT in Parkinson's disease and multiple system atrophy","volume":"33","author":"El Fakhri","year":"2006","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0135","series-title":"Principles and practice of movement disorders","author":"Fahn","year":"2007"},{"key":"10.1016\/bs.irn.2018.08.006_bb0140","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1136\/jnnp.54.2.159","article-title":"Diffuse Lewy body disease presenting with a supranuclear gaze palsy","volume":"54","author":"Fearnley","year":"1991","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"key":"10.1016\/bs.irn.2018.08.006_bb0145","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1097\/01.mnm.0000202858.45522.df","article-title":"123I-FP-CIT in progressive supranuclear palsy and in Parkinson's disease: A SPECT semiquantitative study","volume":"27","author":"Filippi","year":"2006","journal-title":"Nuclear Medicine Communications"},{"key":"10.1016\/bs.irn.2018.08.006_bb0150","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/(SICI)1098-2396(199806)29:2<128::AID-SYN4>3.0.CO;2-9","article-title":"Rapid detection of Parkinson's disease by SPECT with altropane: A selective ligand for dopamine transporters","volume":"29","author":"Fischman","year":"1998","journal-title":"Synapse"},{"key":"10.1016\/bs.irn.2018.08.006_bb0155","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1002\/mds.21989","article-title":"Cardiac sympathetic denervation correlates with clinical and pathologic stages of Parkinson's disease","volume":"23","author":"Fujishiro","year":"2008","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0160","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/B978-0-444-63425-2.00008-8","article-title":"Dopamine receptor heteromeric complexes and their emerging functions","volume":"211","author":"George","year":"2014","journal-title":"Progress in Brain Research"},{"key":"10.1016\/bs.irn.2018.08.006_bb0165","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1212\/WNL.0b013e31826c1b0a","article-title":"[18F]FDG-PET is superior to [123I]IBZM-SPECT for the differential diagnosis of parkinsonism","volume":"79","author":"Hellwig","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0170","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.2967\/jnumed.113.122010","article-title":"123I-iodobenzamide SPECT is not an independent predictor of dopaminergic responsiveness in patients with suspected atypical parkinsonian syndromes","volume":"54","author":"Hellwig","year":"2013","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0175","first-page":"954","article-title":"Loss of dopamine-D2 receptor binding sites in Parkinsonian plus syndromes","volume":"39","author":"Hierholzer","year":"1998","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0180","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson's disease: A clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"key":"10.1016\/bs.irn.2018.08.006_bb9010","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1038\/sj.jcbfm.9600493","article-title":"Consensus nomenclature for in vivo imaging of reversibly binding radioligands","volume":"27","author":"Innis","year":"2007","journal-title":"Journal of Cerebral Blood Flow & Metabolism"},{"key":"10.1016\/bs.irn.2018.08.006_bb0185","doi-asserted-by":"crossref","first-page":"11965","DOI":"10.1073\/pnas.90.24.11965","article-title":"Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease","volume":"90","author":"Innis","year":"1993","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/bs.irn.2018.08.006_bb0190","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1007\/s00259-003-1234-x","article-title":"Regional differences between 99mTc-ECD and 99mTc-HMPAO SPET in perfusion changes with age and gender in healthy adults","volume":"30","author":"Inoue","year":"2003","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0195","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1159\/000314498","article-title":"Single-photon emission computed tomography in diagnosis and differential diagnosis of Parkinson's disease","volume":"7","author":"Isaias","year":"2010","journal-title":"Neurodegenerative Diseases"},{"key":"10.1016\/bs.irn.2018.08.006_bb0200","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/mds.22870","article-title":"Imaging essential tremor","volume":"25","author":"Isaias","year":"2010","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0205","doi-asserted-by":"crossref","first-page":"411","DOI":"10.2217\/iim.12.21","article-title":"[123I]FP-CIT SPECT in atypical degenerative parkinsonism","volume":"4","author":"Isaias","year":"2012","journal-title":"Imaging Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb9015","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1016\/j.jacc.2010.01.014","article-title":"Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView Myocardial Imaging for Risk Evaluation in Heart Failure) study","volume":"55","author":"Jacobson","year":"2010","journal-title":"Journal of the American College of Cardiology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0210","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1001\/archneur.61.8.1224","article-title":"(123I) beta-CIT and single-photon emission computed tomographic imaging vs clinical evaluation in Parkinsonian syndrome: Unmasking an early diagnosis","volume":"61","author":"Jennings","year":"2004","journal-title":"Archives of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0215","first-page":"704","article-title":"Cerebral perfusion in progressive supranuclear palsy","volume":"5","author":"Johnson","year":"1992","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0220","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.2967\/jnumed.116.182139","article-title":"Analysis of extrastriatal 123I-FP-CIT binding contributes to the differential diagnosis of Parkinsonian diseases","volume":"58","author":"Joling","year":"2017","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0225","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00415-011-6163-1","article-title":"Visual assessment of dopaminergic degeneration pattern in 123I-FP-CIT SPECT differentiates patients with atypical parkinsonian syndromes and idiopathic Parkinson's disease","volume":"259","author":"Kahraman","year":"2012","journal-title":"Journal of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0230","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1007\/s00259-009-1266-y","article-title":"EANM procedure guideline for brain perfusion SPECT using 99mTc-labelled radiopharmaceuticals, version 2","volume":"36","author":"Kapucu","year":"2009","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0235","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1097\/WCO.0b013e3283632e83","article-title":"The pallidopyramidal syndromes: Nosology, aetiology and pathogenesis","volume":"26","author":"Kara","year":"2013","journal-title":"Current Opinion in Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0240","first-page":"1099","article-title":"Reduced cardiac uptake and enhanced washout of 123I-MIBG in pure autonomic failure occurs conjointly with Parkinson's disease and dementia with Lewy bodies","volume":"47","author":"Kashihara","year":"2006","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0245","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.parkreldis.2011.07.011","article-title":"Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test","volume":"17","author":"Kikuchi","year":"2011","journal-title":"Parkinsonism & Related Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0250","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/mds.10042","article-title":"Combination of dopamine transporter and D2 receptor SPECT in the diagnostic evaluation of PD, MSA, and PSP","volume":"17","author":"Kim","year":"2002","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0255","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000008124","article-title":"Preclinical impairment of the striatal dopamine transporter system in sporadic olivopontocerebellar atrophy: Studied with [(123)I]beta-CIT and SPECT","volume":"43","author":"Kim","year":"2000","journal-title":"European Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0260","doi-asserted-by":"crossref","first-page":"2530","DOI":"10.1002\/mds.23915","article-title":"Brain perfusion differences in parkinsonian disorders","volume":"26","author":"Kimura","year":"2011","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0265","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1002\/mds.23659","article-title":"Meta-analysis of 123I-MIBG cardiac scintigraphy for the diagnosis of Lewy body-related disorders","volume":"26","author":"King","year":"2011","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0270","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1056\/NEJM198804073181402","article-title":"Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications","volume":"7","author":"Kish","year":"1988","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0275","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1002\/mds.21004","article-title":"Dopamine transporters, D2 receptors, and glucose metabolism in corticobasal degeneration","volume":"21","author":"Klaffke","year":"2006","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0280","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/ana.20009","article-title":"Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B","volume":"55","author":"Klunk","year":"2004","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0285","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1007\/s00259-004-1578-x","article-title":"Imaging of dopamine transporters and D2 receptors in patients with Parkinson's disease and multiple system atrophy","volume":"31","author":"Knudsen","year":"2004","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0290","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1007\/s00415-014-7315-x","article-title":"Motivational modulation of bradykinesia in Parkinson's disease off and on dopaminergic medication","volume":"261","author":"Kojovic","year":"2014","journal-title":"Journal of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0295","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1002\/mds.21614","article-title":"Diffusion weighted imaging best discriminates PD from MSA-P: A comparison with tilt table testing and heart MIBG scintigraphy","volume":"22","author":"K\u00f6llensperger","year":"2007","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0300","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.2967\/jnumed.111.102277","article-title":"Assessing the optimal time point for the measurement of extrastriatal serotonin transporter binding with 123I-FP-CIT SPECT in healthy, male subjects","volume":"53","author":"Koopman","year":"2012","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0305","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1002\/mds.25975","article-title":"Correlation of striatal dopamine transporter imaging with post mortem substantia nigra cell counts","volume":"29","author":"Kraemmer","year":"2014","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0310","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1002\/mds.20611","article-title":"Corticobasal degeneration and Parkinson's disease assessed by HmPaO SPECT: The utility of factorial discriminant analysis","volume":"20","author":"Kreisler","year":"2005","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0315","first-page":"196","article-title":"Quantifying local cerebral blood flow by N-isopropyl-p-[123I]iodoamphetamine (IMP) tomography","volume":"23","author":"Kuhl","year":"1982","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0320","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1007\/BF01254479","article-title":"Imaging of dopamine transporters in humans with technetium-99m TRODAT-1","volume":"23","author":"Kung","year":"1996","journal-title":"European Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0325","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S0001-2998(05)80235-1","article-title":"Current and future radiopharmaceuticals for brain imaging with single photon emission computed tomography","volume":"20","author":"Kung","year":"1990","journal-title":"Seminars in Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0330","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/00006231-200404000-00005","article-title":"Imaging early-stage corticobasal degeneration with [99mTc]TRODAT-1 SPET","volume":"25","author":"Lai","year":"2004","journal-title":"Nuclear Medicine Communications"},{"key":"10.1016\/bs.irn.2018.08.006_bb0335","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1212\/WNL.44.8.1436","article-title":"Parietal Pick's disease mimicking cortical-basal ganglionic degeneration","volume":"44","author":"Lang","year":"1994","journal-title":"Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0340","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/ana.22424","article-title":"Clinicopathological correlations in corticobasal degeneration","volume":"70","author":"Lee","year":"2011","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0345","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1097\/MNM.0b013e32833e5f90","article-title":"Preliminary studies of differential impairments of the dopaminergic system in subtypes of progressive supranuclear palsy","volume":"31","author":"Lin","year":"2010","journal-title":"Nuclear Medicine Communications"},{"key":"10.1016\/bs.irn.2018.08.006_bb0350","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1212\/WNL.46.4.922","article-title":"Accuracy of clinical criteria for the diagnosis of progressive supranuclear palsy (Steele\u2013Richardson\u2013Olszewski syndrome)","volume":"46","author":"Litvan","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0355","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/mds.10459","article-title":"Movement disorders society scientific issues committee report: SIC task force appraisal of clinical diagnostic criteria for Parkinsonian disorders","volume":"18","author":"Litvan","year":"2003","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0360","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1136\/jnnp.65.5.717","article-title":"Neuropsychiatric features of corticobasal degeneration","volume":"65","author":"Litvan","year":"1998","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"key":"10.1016\/bs.irn.2018.08.006_bb0365","doi-asserted-by":"crossref","DOI":"10.2967\/jnumed.118.208215","article-title":"First-in-human brain imaging of Alzheimer dementia patients and elderly controls with 18F-MK-6240, a PET tracer targeting neurofibrillary tangle pathology","author":"Lohith","year":"2018","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0370","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1007\/s00259-002-0938-7","article-title":"Clinical impact of diagnostic SPET investigations with a dopamine re-uptake ligand","volume":"29","author":"L\u00f8kkegaard","year":"2002","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0375","first-page":"49","article-title":"99mTc-TRODAT-1 imaging of multiple system atrophy","volume":"45","author":"Lu","year":"2004","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0380","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S1474-4422(04)00936-6","article-title":"Corticobasal degeneration","volume":"3","author":"Mahapatra","year":"2004","journal-title":"Lancet Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0385","first-page":"1540","article-title":"A multicenter assessment of dopamine transporter imaging with DOPASCAN\/SPECT in parkinsonism. Parkinson study group","volume":"28","author":"Marek","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0390","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/mds.870100208","article-title":"Patterns of regional cerebral blood flow in corticobasal degeneration studied using HMPAO SPECT; comparison with Parkinson's disease and normal controls","volume":"10","author":"Markus","year":"1995","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0395","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1471-2342-10-17","article-title":"Evaluation of both perfusion and atrophy in multiple system atrophy of the cerebellar type using brain SPECT alone","volume":"10","author":"Matsuda","year":"2010","journal-title":"BMC Medical Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0400","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.parkreldis.2005.01.001","article-title":"Brain perfusion differences between Parkinson's disease and multiple system atrophy with predominant parkinsonian features","volume":"11","author":"Matsui","year":"2005","journal-title":"Parkinsonism & Related Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0405","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1021\/bc960029l","article-title":"Tc-99m-labeled tropanes as dopamine transporter imaging agents","volume":"7","author":"Meegalla","year":"1996","journal-title":"Bioconjugate Chemistry"},{"key":"10.1016\/bs.irn.2018.08.006_bb0410","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1007\/s002590050295","article-title":"Differential distribution of striatal [123I]beta-CIT in Parkinson's disease and progressive supranuclear palsy, evaluated with single-photon emission tomography","volume":"25","author":"Messa","year":"1998","journal-title":"European Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0415","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s13195-014-0071-4","article-title":"Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography","volume":"6","author":"Misch","year":"2014","journal-title":"Alzheimer's Research & Therapy"},{"key":"10.1016\/bs.irn.2018.08.006_bb0420","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1093\/sleep\/31.5.717","article-title":"123I-MIBG cardiac scintigraphy provides clues to the underlying neurodegenerative disorder in idiopathic REM sleep behavior disorder","volume":"31","author":"Miyamoto","year":"2008","journal-title":"Sleep"},{"key":"10.1016\/bs.irn.2018.08.006_bb0425","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1007\/s00259-010-1520-3","article-title":"Pre- and postsynaptic dopamine SPECT in the early phase of idiopathic parkinsonism: A population-based study","volume":"37","author":"Mo","year":"2010","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0430","first-page":"584","article-title":"Binding of [99mTc]TRODAT-1 to dopamine transporters in patients with Parkinson's disease and in healthy volunteers","volume":"41","author":"Mozley","year":"2000","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0435","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1007\/s00415-011-6108-8","article-title":"Subclinical nigrostriatal dopaminergic denervation in the cerebellar subtype of multiple system atrophy (MSA-C)","volume":"258","author":"Mu\u00f1oz","year":"2011","journal-title":"Journal of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0440","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1136\/jnnp.2004.037028","article-title":"Reliability of MIBG myocardial scintigraphy in the diagnosis of Parkinson's disease","volume":"76","author":"Nagayama","year":"2005","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"key":"10.1016\/bs.irn.2018.08.006_bb0445","doi-asserted-by":"crossref","first-page":"535","DOI":"10.2169\/internalmedicine.49.2785","article-title":"Classification of cerebellar atrophy using voxel-based morphometry and SPECT with an easy Z-score imaging system","volume":"49","author":"Nanri","year":"2010","journal-title":"Internal Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0450","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1093\/brain\/124.7.1438","article-title":"The prevalence of progressive supranuclear palsy (Steele\u2013Richardson\u2013Olszewski syndrome) in the UK","volume":"124","author":"Nath","year":"2001","journal-title":"Brain"},{"key":"10.1016\/bs.irn.2018.08.006_bb0455","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jns.2017.11.039","article-title":"Scan without evidence of dopaminergic deficit (SWEDD) in degenerative parkinsonism and dementia with Lewy bodies: A prospective study","volume":"385","author":"Nicastro","year":"2018","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/bs.irn.2018.08.006_bb0460","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1097\/RLU.0000000000001899","article-title":"123I-FP-CIT SPECT accurately distinguishes parkinsonian from cerebellar variant of multiple system atrophy","volume":"43","author":"Nicastro","year":"2018","journal-title":"Clinical Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0465","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1007\/s00259-012-2100-5","article-title":"Progression of dopamine transporter decline in patients with the Parkinson variant of multiple system atrophy: A voxel-based analysis of [123I]\u03b2-CIT SPECT","volume":"39","author":"Nocker","year":"2012","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0470","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1159\/000051262","article-title":"Comparison of brain perfusion in corticobasal degeneration and Alzheimer's disease","volume":"12","author":"Okuda","year":"2001","journal-title":"Dementia and Geriatric Cognitive Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0475","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.parkreldis.2012.01.009","article-title":"123I-MIBG myocardial scintigraphy for differentiating Parkinson's disease from other neurodegenerative parkinsonism: A systematic review and meta-analysis","volume":"17","author":"Orimo","year":"2012","journal-title":"Parkinsonism & Related Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0480","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/j.1750-3639.2006.00032.x","article-title":"Degeneration of cardiac sympathetic nerve begins in the early disease process of Parkinson's disease","volume":"17","author":"Orimo","year":"2007","journal-title":"Brain Pathology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0485","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1552-6569.2002.tb00139.x","article-title":"Comparison of striatal dopamine D2 receptors in Parkinson's disease and progressive supranuclear palsy patients using [123I] iodobenzofuran single-photon emission computed tomography","volume":"12","author":"Oyanagi","year":"2002","journal-title":"Journal of Neuroimaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0490","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1093\/brain\/awh303","article-title":"The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: Clinicopathological correlations","volume":"127","author":"Ozawa","year":"2004","journal-title":"Brain"},{"key":"10.1016\/bs.irn.2018.08.006_bb0495","doi-asserted-by":"crossref","first-page":"5700","DOI":"10.1523\/JNEUROSCI.0523-05.2005","article-title":"Bradykinesia induced by dopamine D2 receptor blockade is associated with reduced motor cortex activity in the rat","volume":"25","author":"Parr-Brownlie","year":"2005","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/bs.irn.2018.08.006_bb0500","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/mds.24000","article-title":"Dopamine transporter imaging in autopsy-confirmed Parkinson's disease and multiple system atrophy","volume":"27","author":"Perju-Dumbrava","year":"2012","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0505","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1093\/brain\/122.8.1449","article-title":"Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: Rostrocaudal distribution","volume":"122","author":"Piggott","year":"1999","journal-title":"Brain"},{"key":"10.1016\/bs.irn.2018.08.006_bb0510","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1002\/1531-8257(200011)15:6<1158::AID-MDS1015>3.0.CO;2-0","article-title":"[123I]beta-CIT SPECT in multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration","volume":"15","author":"Pirker","year":"2000","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0515","first-page":"1711","article-title":"Iodine-123-epidepride-SPECT: Studies in Parkinson's disease, multiple system atrophy and Huntington's disease","volume":"38","author":"Pirker","year":"1997","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0520","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/mds.1265","article-title":"Progression of dopaminergic degeneration in Parkinson's disease and atypical parkinsonism: A longitudinal beta-CIT SPECT study","volume":"17","author":"Pirker","year":"2002","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb9020","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.parkreldis.2012.10.010","article-title":"Dopamine D2 receptor SPECT in corticobasal syndrome and autopsy-confirmed corticobasal degeneration","volume":"19","author":"Pirker","year":"2013","journal-title":"Parkinsonism & Related Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0525","doi-asserted-by":"crossref","first-page":"907","DOI":"10.3233\/JPD-150625","article-title":"Progressive dopamine transporter binding loss in autopsy-confirmed corticobasal degeneration","volume":"5","author":"Pirker","year":"2015","journal-title":"Journal of Parkinson's Disease"},{"key":"10.1016\/bs.irn.2018.08.006_bb0530","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00702-004-0208-x","article-title":"Combined 123I-FP-CIT and 123I-IBZM SPECT for the diagnosis of Parkinsonian syndromes: Study on 72 patients","volume":"112","author":"Plotkin","year":"2005","journal-title":"Journal of Neural Transmission (Vienna)"},{"key":"10.1016\/bs.irn.2018.08.006_bb0535","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0006-8993(91)90554-9","article-title":"A post-mortem study on striatal dopamine receptors in Parkinson's disease","volume":"556","author":"Rinne","year":"1991","journal-title":"Brain Research"},{"key":"10.1016\/bs.irn.2018.08.006_bb0540","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1002\/mds.23179","article-title":"Midbrain SERT in degenerative parkinsonisms: A 123I-FP-CIT SPECT study","volume":"25","author":"Roselli","year":"2010","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0545","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/mds.870130506","article-title":"Dopamine D3 receptor is decreased and D2 receptor is elevated in the striatum of Parkinson's disease","volume":"13","author":"Ryoo","year":"1998","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0550","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/j.1468-1331.2004.00872.x","article-title":"Reduced cerebellar vermis activation during urinary storage and micturition in multiple system atrophy: 99mTc-labelled ECD SPECT study","volume":"11","author":"Sakakibara","year":"2004","journal-title":"European Journal of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0555","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/s12149-014-0928-4","article-title":"The utility of cerebral perfusion SPECT analysis using SPM8, eZIS and vbSEE for the diagnosis of multiple system atrophy-parkinsonism","volume":"29","author":"Sakurai","year":"2015","journal-title":"Annals of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0560","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/mds.870080406","article-title":"Correlation of clinical response in apomorphine test with D2-receptor status as demonstrated by 123I IBZM-SPECT","volume":"8","author":"Schelosky","year":"1993","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0565","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1093\/brain\/awh485","article-title":"Voxel-wise analysis of [123I]beta-CIT SPECT differentiates the Parkinson variant of multiple system atrophy from idiopathic Parkinson's disease","volume":"128","author":"Scherfler","year":"2005","journal-title":"Brain"},{"key":"10.1016\/bs.irn.2018.08.006_bb0570","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1136\/jnnp.57.9.1047","article-title":"Multiple system atrophy: Natural history, MRI morphology, and dopamine receptor imaging with 123IBZM-SPECT","volume":"57","author":"Schulz","year":"1994","journal-title":"Journal of Neurology, Neurosurgery, & Psychiatry"},{"key":"10.1016\/bs.irn.2018.08.006_bb0575","first-page":"17","article-title":"123I-iodobenzamide-SPECT in 83 patients with de novo parkinsonism","volume":"43","author":"Schwarz","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb9025","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1002\/mds.870120610","article-title":"[123]IBZM binding predicts dopaminergic responsiveness in patients with parkinsonism and previous dopaminomimetic therapy","volume":"12","author":"Schwarz","year":"1997","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0580","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/mds.870130107","article-title":"123I-IBZM binding compared with long-term clinical follow up in patients with de novo parkinsonism","volume":"13","author":"Schwarz","year":"1998","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0585","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/ana.410380407","article-title":"Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease","volume":"38","author":"Seibyl","year":"1995","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0590","first-page":"1453","article-title":"Test\/retest reproducibility of iodine-123-betaCIT SPECT brain measurement of dopamine transporters in Parkinson's patients","volume":"38","author":"Seibyl","year":"1997","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0595","first-page":"1500","article-title":"Iodine-123-beta-CIT and iodine-123-FPCIT SPECT measurement of dopamine transporters in healthy subjects and Parkinson's patients","volume":"39","author":"Seibyl","year":"1998","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0600","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1001\/archneur.63.8.1154","article-title":"Topography of dopamine transporter availability in progressive supranuclear palsy: A voxelwise [123I]beta-CIT SPECT analysis","volume":"63","author":"Seppi","year":"2006","journal-title":"Archives of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0605","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1002\/mds.20229","article-title":"Comparison of diffusion-weighted imaging and [123I]IBZM-SPECT for the differentiation of patients with the Parkinson variant of multiple system atrophy from those with Parkinson's disease","volume":"19","author":"Seppi","year":"2004","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0610","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1212\/WNL.0b013e3181ab2b58","article-title":"Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET","volume":"73","author":"Shimada","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0615","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3988\/jcn.2006.2.1.51","article-title":"Clinical implications of cardiac-MIBG SPECT in the differentiation of parkinsonian syndromes","volume":"2","author":"Shin","year":"2006","journal-title":"Journal of Clinical Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0620","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1002\/ana.410340304","article-title":"Human positron emission tomographic [18F]fluorodopa studies correlate with dopamine cell counts and levels","volume":"34","author":"Snow","year":"1993","journal-title":"Annals of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0625","doi-asserted-by":"crossref","first-page":"714","DOI":"10.2967\/jnumed.112.110106","article-title":"Value of semiquantitative analysis for clinical reporting of 123I-2-\u03b2-carbomethoxy-3\u03b2-(4-iodophenyl)-N-(3-fluoropropyl)nortropane SPECT studies","volume":"54","author":"S\u00f6derlund","year":"2013","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0630","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1097\/MNM.0000000000000354","article-title":"The value of brain perfusion SPECT for differentiation between mildly symptomatic idiopathic Parkinson's disease and the Parkinson variant of multiple system atrophy","volume":"36","author":"Song","year":"2015","journal-title":"Nuclear Medicine Communications"},{"key":"10.1016\/bs.irn.2018.08.006_bb0635","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00702-006-0518-2","article-title":"Striatal FP-CIT uptake differs in the subtypes of early Parkinson's disease","volume":"114","author":"Spiegel","year":"2007","journal-title":"Journal of Neural Transmission (Vienna)"},{"key":"10.1016\/bs.irn.2018.08.006_bb0640","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s00259-004-1733-4","article-title":"Early-stage [123I]beta-CIT SPECT and long-term clinical follow-up in patients with an initial diagnosis of Parkinson's disease","volume":"32","author":"Stoffers","year":"2005","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0645","doi-asserted-by":"crossref","first-page":"733","DOI":"10.2967\/jnumed.110.086959","article-title":"Diagnostic accuracy of combined FP-CIT, IBZM, and MIBG scintigraphy in the differential diagnosis of degenerative parkinsonism: A multidimensional statistical approach","volume":"52","author":"S\u00fcdmeyer","year":"2011","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0650","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/s00259-004-1667-x","article-title":"Differences in [99mTc]TRODAT-1 SPECT binding to dopamine transporters in patients with multiple system atrophy and Parkinson's disease","volume":"32","author":"Swanson","year":"2005","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb9030","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1136\/jnnp-2015-310686","article-title":"Quantitative correlation between cardiac MIBG uptake and remaining axons in the cardiac sympathetic nerve in Lewy body disease","volume":"86","author":"Takahashi","year":"2015","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"key":"10.1016\/bs.irn.2018.08.006_bb0655","first-page":"71","article-title":"Cardiac sympathetic denervation from the early stage of Parkinson's disease: Clinical and experimental studies with radiolabeled MIBG","volume":"41","author":"Takatsu","year":"2000","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0660","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.parkreldis.2017.11.333","article-title":"Differential diagnosis of parkinsonian syndromes using dopamine transporter and perfusion SPECT","volume":"47","author":"Takaya","year":"2018","journal-title":"Parkinsonism & Related Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0665","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/BF00881814","article-title":"Relationship between clinical features of Parkinson's disease and presynaptic dopamine transporter binding assessed with [123I]IPT and single-photon emission tomography","volume":"24","author":"Tatsch","year":"1997","journal-title":"European Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0670","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1002\/mds.22098","article-title":"[123I]FP-CIT SPET imaging in drug-induced parkinsonism","volume":"15","author":"Tinazzi","year":"2008","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0675","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nrn1008","article-title":"Plasma membrane monoamine transporters: Structure, regulation and function","volume":"4","author":"Torres","year":"2003","journal-title":"Nature Reviews. Neuroscience"},{"key":"10.1016\/bs.irn.2018.08.006_bb0680","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1002\/mds.27125","article-title":"Clinicopathologic discrepancies in a population-based incidence study of parkinsonism in olmsted county: 1991\u20132010","volume":"32","author":"Turcano","year":"2017","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0685","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/mds.10578","article-title":"Dopamine transporter: Basic science and human variation of a key molecule for dopaminergic function, locomotion, and parkinsonism","volume":"18","author":"Uhl","year":"2003","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0690","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/35041572","article-title":"Distinct functions of the two isoforms of dopamine D2 receptors","volume":"408","author":"Usiello","year":"2000","journal-title":"Nature"},{"key":"10.1016\/bs.irn.2018.08.006_bb0695","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1007\/s00259-004-1480-6","article-title":"Dopamine transporter SPECT using fast kinetic ligands: 123I-FP-beta-CIT versus 99mTc-TRODAT-1","volume":"31","author":"Van Laere","year":"2004","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0700","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1007\/s00259-009-1265-z","article-title":"EANM procedure guidelines for brain neurotransmission SPECT\/PET using dopamine D2 receptor ligands, version 2","volume":"37","author":"Van Laere","year":"2010","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0705","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1001\/archneur.1993.00540050063017","article-title":"Multiple system atrophy and progressive supranuclear palsy. Diminished striatal D2 dopamine receptor activity demonstrated by 123I-IBZM single photon emission computed tomography","volume":"50","author":"Van Royen","year":"1993","journal-title":"Archives of Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0710","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s00259-012-2276-8","article-title":"European multicentre database of healthy controls for [123I]FP-CIT SPECT (ENC-DAT): Age-related effects, gender differences and evaluation of different methods of analysis","volume":"40","author":"Varrone","year":"2013","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0715","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1002\/mds.1256","article-title":"[(123)I]beta-CIT SPECT imaging demonstrates reduced density of striatal dopamine transporters in Parkinson's disease and multiple system atrophy","volume":"16","author":"Varrone","year":"2001","journal-title":"Movement Disorders"},{"key":"10.1016\/bs.irn.2018.08.006_bb0720","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1007\/s00259-006-0344-7","article-title":"Identification by [99mTc]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease","volume":"34","author":"Varrone","year":"2007","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0725","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s00259-007-0611-2","article-title":"Variations in 123I-metaiodobenzylguanidine (MIBG) late heart mediastinal ratios in chronic heart failure: A need for standardisation and validation","volume":"35","author":"Verberne","year":"2008","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"},{"key":"10.1016\/bs.irn.2018.08.006_bb0730","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1159\/000115640","article-title":"Diagnostic value of 123I-ioflupane and 123I-iodobenzamide SPECT scans in 248 patients with parkinsonian syndromes","volume":"59","author":"Vlaar","year":"2008","journal-title":"European Neurology"},{"key":"10.1016\/bs.irn.2018.08.006_bb0735","first-page":"393","article-title":"Sensitivity and specificity of 99mTc-TRODAT-1 SPECT imaging in differentiating patients with idiopathic Parkinson's disease from healthy subjects","volume":"45","author":"Weng","year":"2004","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/bs.irn.2018.08.006_bb0740","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1007\/s00702-007-0746-0","article-title":"Features of probable multiple system atrophy patients identified among 4770 patients with parkinsonism enrolled in the multicentre registry of the German competence network on Parkinson's disease","volume":"114","author":"W\u00fcllner","year":"2007","journal-title":"Journal of Neural Transmission (Vienna)"},{"key":"10.1016\/bs.irn.2018.08.006_bb0745","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0022-510X(97)00278-5","article-title":"Differentiation of idiopathic Parkinson's disease from striatonigral degeneration and progressive supranuclear palsy using iodine-123 meta-iodobenzylguanidine myocardial scintigraphy","volume":"155","author":"Yoshita","year":"1998","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/bs.irn.2018.08.006_bb0750","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1097\/00006231-200107000-00007","article-title":"Differentiating between progressive supranuclear palsy and corticobasal degeneration by brain perfusion SPET","volume":"22","author":"Zhang","year":"2001","journal-title":"Nuclear Medicine Communications"},{"key":"10.1016\/bs.irn.2018.08.006_bb0755","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s00259-011-1976-9","article-title":"Predictive value of dopamine transporter SPECT imaging with [123I]PE2I in patients with subtle parkinsonian symptoms","volume":"39","author":"Ziebell","year":"2012","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"}],"container-title":["International Review of Neurobiology","Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0074774218300734?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0074774218300734?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T04:59:02Z","timestamp":1571806742000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0074774218300734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9780128151419"],"references-count":155,"URL":"https:\/\/doi.org\/10.1016\/bs.irn.2018.08.006","relation":{},"ISSN":["0074-7742"],"issn-type":[{"value":"0074-7742","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}