{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:13:49Z","timestamp":1790741629963,"version":"4.1.0"},"reference-count":133,"publisher":"Elsevier","isbn-type":[{"value":"9780128034736","type":"print"}],"license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017]]},"DOI":"10.1016\/bs.mcb.2016.10.008","type":"book-chapter","created":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T15:41:03Z","timestamp":1481298063000},"page":"193-220","source":"Crossref","is-referenced-by-count":11,"title":["Studying disorders of vertebrate iron and heme metabolism using zebrafish"],"prefix":"10.1016","member":"78","reference":[{"issue":"26","key":"10.1016\/bs.mcb.2016.10.008_bib1","doi-asserted-by":"crossref","first-page":"19906","DOI":"10.1074\/jbc.M000713200","article-title":"A novel mammalian iron-regulated protein involved in intracellular iron metabolism","volume":"275","author":"Abboud","year":"2000","journal-title":"The Journal of Biological Chemistry"},{"issue":"6","key":"10.1016\/bs.mcb.2016.10.008_bib2","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.devcel.2015.01.032","article-title":"A CRISPR\/Cas9 vector system for tissue-specific gene disruption in zebrafish","volume":"32","author":"Ablain","year":"2015","journal-title":"Developmental Cell"},{"issue":"7","key":"10.1016\/bs.mcb.2016.10.008_bib3","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.bbamcr.2006.05.005","article-title":"Biosynthesis of heme in mammals","volume":"1763","author":"Ajioka","year":"2006","journal-title":"Biochimica et Biophysica Acta"},{"issue":"6","key":"10.1016\/bs.mcb.2016.10.008_bib4","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1093\/bfgp\/eln043","article-title":"Emerging gene knockout technology in zebrafish: zinc-finger nucleases","volume":"7","author":"Amacher","year":"2008","journal-title":"Briefings in Functional Genomics and Proteomics"},{"issue":"5394","key":"10.1016\/bs.mcb.2016.10.008_bib5","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1126\/science.282.5394.1711","article-title":"Zebrafish hox clusters and vertebrate genome evolution","volume":"282","author":"Amores","year":"1998","journal-title":"Science"},{"issue":"9","key":"10.1016\/bs.mcb.2016.10.008_bib7","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1016\/j.bbamcr.2012.05.010","article-title":"Mammalian iron metabolism and its control by iron regulatory proteins","volume":"1823","author":"Anderson","year":"2012","journal-title":"Biochimica et Biophysica Acta"},{"issue":"26","key":"10.1016\/bs.mcb.2016.10.008_bib6","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1182\/blood-2015-07-659276","article-title":"Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression","volume":"126","author":"Anderson","year":"2015","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2016.10.008_bib8","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1146\/annurev.physiol.69.031905.164337","article-title":"Iron homeostasis","volume":"69","author":"Andrews","year":"2007","journal-title":"Annual Review of Physiology"},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib9","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ymeth.2014.03.027","article-title":"CRISPR\/Cas9 and TALEN-mediated knock-in approaches in zebrafish","volume":"69","author":"Auer","year":"2014","journal-title":"Methods"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib10","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1101\/gr.161638.113","article-title":"Highly efficient CRISPR\/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair","volume":"24","author":"Auer","year":"2014","journal-title":"Genome Research"},{"issue":"26","key":"10.1016\/bs.mcb.2016.10.008_bib11","doi-asserted-by":"crossref","first-page":"16537","DOI":"10.1073\/pnas.262420099","article-title":"Chemical complementation: a reaction-independent genetic assay for enzyme catalysis","volume":"99","author":"Baker","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"Pt 2","key":"10.1016\/bs.mcb.2016.10.008_bib12","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1093\/brain\/awt328","article-title":"Variant non ketotic hyperglycinemia is caused by mutations in LIAS, BOLA3 and the novel gene GLRX5","volume":"137","author":"Baker","year":"2014","journal-title":"Brain"},{"issue":"7422","key":"10.1016\/bs.mcb.2016.10.008_bib13","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/nature11537","article-title":"In vivo genome editing using a high-efficiency TALEN system","volume":"491","author":"Bedell","year":"2012","journal-title":"Nature"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib14","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1089\/zeb.2008.0555","article-title":"A primer for morpholino use in zebrafish","volume":"6","author":"Bill","year":"2009","journal-title":"Zebrafish"},{"issue":"8","key":"10.1016\/bs.mcb.2016.10.008_bib15","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1101\/gad.7.8.1620","article-title":"Sequence-specific endonucleolytic cleavage and protection of mRNA in Xenopus and Drosophila","volume":"7","author":"Brown","year":"1993","journal-title":"Genes and Development"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib16","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/3049","article-title":"Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia","volume":"20","author":"Brownlie","year":"1998","journal-title":"Nature Genetics"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib17","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0012-1606(02)00041-6","article-title":"Characterization of embryonic globin genes of the zebrafish","volume":"255","author":"Brownlie","year":"2003","journal-title":"Developmental Biology"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib18","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1182\/blood-2007-02-072520","article-title":"The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload","volume":"110","author":"Camaschella","year":"2007","journal-title":"Blood"},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/GIM.0b013e3181cd68ed","article-title":"Beta-thalassemia","volume":"12","author":"Cao","year":"2010","journal-title":"Genetics in Medicine"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib20","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/cr.2013.45","article-title":"Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos","volume":"23","author":"Chang","year":"2013","journal-title":"Cell Research"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib21","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.cmet.2013.01.013","article-title":"Snx3 regulates recycling of the transferrin receptor and iron assimilation","volume":"17","author":"Chen","year":"2013","journal-title":"Cell Metabolism"},{"issue":"16","key":"10.1016\/bs.mcb.2016.10.008_bib22","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0960-9822(00)00653-9","article-title":"Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria","volume":"10","author":"Childs","year":"2000","journal-title":"Current Biology"},{"issue":"11","key":"10.1016\/bs.mcb.2016.10.008_bib23","doi-asserted-by":"crossref","first-page":"7835","DOI":"10.1074\/jbc.M114.547778","article-title":"Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria","volume":"289","author":"Chung","year":"2014","journal-title":"The Journal of Biological Chemistry"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib24","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1097\/MOH.0b013e328351c48b","article-title":"Heme metabolism and erythropoiesis","volume":"19","author":"Chung","year":"2012","journal-title":"Current Opinion in Hematology"},{"issue":"8","key":"10.1016\/bs.mcb.2016.10.008_bib25","doi-asserted-by":"crossref","first-page":"e1002861","DOI":"10.1371\/journal.pgen.1002861","article-title":"Simple methods for generating and detecting locus-specific mutations induced with TALENs in the zebrafish genome","volume":"8","author":"Dahlem","year":"2012","journal-title":"PLoS Genetics"},{"issue":"7","key":"10.1016\/bs.mcb.2016.10.008_bib26","doi-asserted-by":"crossref","first-page":"756","DOI":"10.7150\/ijbs.6.756","article-title":"Non-homologous end joining plays a key role in transgene concatemer formation in transgenic zebrafish embryos","volume":"6","author":"Dai","year":"2010","journal-title":"International Journal of Biological Sciences"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib27","doi-asserted-by":"crossref","first-page":"a011676","DOI":"10.1101\/cshperspect.a011676","article-title":"Erythroid heme biosynthesis and its disorders","volume":"3","author":"Dailey","year":"2013","journal-title":"Cold Spring Harbor Perspectives in Medicine"},{"issue":"8","key":"10.1016\/bs.mcb.2016.10.008_bib28","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1073\/pnas.80.8.2258","article-title":"pH and the recycling of transferrin during receptor-mediated endocytosis","volume":"80","author":"Dautry-Varsat","year":"1983","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"23","key":"10.1016\/bs.mcb.2016.10.008_bib29","doi-asserted-by":"crossref","first-page":"10713","DOI":"10.1073\/pnas.92.23.10713","article-title":"Intraembryonic hematopoietic cell migration during vertebrate development","volume":"92","author":"Detrich","year":"1995","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"13","key":"10.1016\/bs.mcb.2016.10.008_bib30","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1182\/blood-2002-04-1169","article-title":"The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1)","volume":"100","author":"Donovan","year":"2002","journal-title":"Blood"},{"issue":"6771","key":"10.1016\/bs.mcb.2016.10.008_bib31","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/35001596","article-title":"Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter","volume":"403","author":"Donovan","year":"2000","journal-title":"Nature"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib32","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.cmet.2005.01.003","article-title":"The iron exporter ferroportin\/Slc40a1 is essential for iron homeostasis","volume":"1","author":"Donovan","year":"2005","journal-title":"Cell Metabolism"},{"issue":"9","key":"10.1016\/bs.mcb.2016.10.008_bib33","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.exphem.2008.04.008","article-title":"montalcino, A zebrafish model for variegate porphyria","volume":"36","author":"Dooley","year":"2008","journal-title":"Experimental Hematology"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib34","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1002\/gene.1053","article-title":"Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown","volume":"30","author":"Draper","year":"2001","journal-title":"Genesis"},{"key":"10.1016\/bs.mcb.2016.10.008_bib35","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1242\/dev.123.1.37","article-title":"A genetic screen for mutations affecting embryogenesis in zebrafish","volume":"123","author":"Driever","year":"1996","journal-title":"Development"},{"issue":"10","key":"10.1016\/bs.mcb.2016.10.008_bib36","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1242\/dev.001115","article-title":"Controlling morpholino experiments: don't stop making antisense","volume":"135","author":"Eisen","year":"2008","journal-title":"Development"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib37","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/gene.1038","article-title":"Morphant technology in model developmental systems","volume":"30","author":"Ekker","year":"2001","journal-title":"Genesis"},{"key":"10.1016\/bs.mcb.2016.10.008_bib38","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1039\/CT8946500899","article-title":"Oxidation of tartaric acid in presence of iron","volume":"65","author":"Fenton","year":"1894","journal-title":"Journal of the Chemical Society, Transactions"},{"key":"10.1016\/bs.mcb.2016.10.008_bib39","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/2045-3701-1-32","article-title":"Transient knockdown and overexpression reveal a developmental role for the zebrafish enosf1b gene","volume":"1","author":"Finckbeiner","year":"2011","journal-title":"Cell and Bioscience"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib40","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/ng0897-383","article-title":"Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene","volume":"16","author":"Fleming","year":"1997","journal-title":"Nature Genetics"},{"issue":"27","key":"10.1016\/bs.mcb.2016.10.008_bib41","doi-asserted-by":"crossref","first-page":"24475","DOI":"10.1074\/jbc.M111789200","article-title":"Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain","volume":"277","author":"Foury","year":"2002","journal-title":"The Journal of Biological Chemistry"},{"issue":"12","key":"10.1016\/bs.mcb.2016.10.008_bib42","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1182\/blood-2008-06-165340","article-title":"Transferrin-a modulates hepcidin expression in zebrafish embryos","volume":"113","author":"Fraenkel","year":"2009","journal-title":"Blood"},{"issue":"6","key":"10.1016\/bs.mcb.2016.10.008_bib43","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1172\/JCI23780","article-title":"Ferroportin1 is required for normal iron cycling in zebrafish","volume":"115","author":"Fraenkel","year":"2005","journal-title":"The Journal of Clinical Investigation"},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib44","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ydbio.2012.03.021","article-title":"Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR","volume":"366","author":"Ganis","year":"2012","journal-title":"Developmental Biology"},{"key":"10.1016\/bs.mcb.2016.10.008_bib136","first-page":"629","article-title":"Transplantation in zebrafish","volume":"Vol. 138","author":"Gansner","year":"2016"},{"issue":"9","key":"10.1016\/bs.mcb.2016.10.008_bib45","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1016\/j.bbamcr.2012.01.014","article-title":"Hepcidin and iron homeostasis","volume":"1823","author":"Ganz","year":"2012","journal-title":"Biochimica et Biophysica Acta"},{"issue":"6","key":"10.1016\/bs.mcb.2016.10.008_bib46","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/sj.thj.6200063","article-title":"Biochemical and genetic defects underlying human congenital hypotransferrinemia","volume":"1","author":"Goldwurm","year":"2000","journal-title":"The Hematology Journal"},{"issue":"17","key":"10.1016\/bs.mcb.2016.10.008_bib47","doi-asserted-by":"crossref","first-page":"3379","DOI":"10.1242\/dev.125.17.3379","article-title":"Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes","volume":"125","author":"Griffin","year":"1998","journal-title":"Development"},{"key":"10.1016\/bs.mcb.2016.10.008_bib48","article-title":"Restored iron transport by a small molecule promotes gut absorption and hemoglobinization","author":"Grillo","year":"2016","journal-title":"Science"},{"issue":"6641","key":"10.1016\/bs.mcb.2016.10.008_bib49","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/41343","article-title":"Cloning and characterization of a mammalian proton-coupled metal-ion transporter","volume":"388","author":"Gunshin","year":"1997","journal-title":"Nature"},{"issue":"8","key":"10.1016\/bs.mcb.2016.10.008_bib50","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1182\/blood-2005-02-0716","article-title":"Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice","volume":"106","author":"Gunshin","year":"2005","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2016.10.008_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1242\/dev.123.1.1","article-title":"The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio","volume":"123","author":"Haffter","year":"1996","journal-title":"Development"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib52","first-page":"201","article-title":"Studies on familial hypotransferrinemia: unique clinical course and molecular pathology","volume":"53","author":"Hayashi","year":"1993","journal-title":"American Journal of Human Genetics"},{"issue":"21","key":"10.1016\/bs.mcb.2016.10.008_bib53","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1182\/blood-2016-01-678151","article-title":"A genome editing primer for the hematologist","volume":"127","author":"Hoban","year":"2016","journal-title":"Blood"},{"issue":"6","key":"10.1016\/bs.mcb.2016.10.008_bib54","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.devcel.2016.02.015","article-title":"Precise editing of the zebrafish genome made simple and efficient","volume":"36","author":"Hoshijima","year":"2016","journal-title":"Developmental Cell"},{"issue":"7446","key":"10.1016\/bs.mcb.2016.10.008_bib55","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature12111","article-title":"The zebrafish reference genome sequence and its relationship to the human genome","volume":"496","author":"Howe","year":"2013","journal-title":"Nature"},{"issue":"24","key":"10.1016\/bs.mcb.2016.10.008_bib56","doi-asserted-by":"crossref","first-page":"4982","DOI":"10.1242\/dev.099085","article-title":"Efficient CRISPR\/Cas9 genome editing with low off-target effects in zebrafish","volume":"140","author":"Hruscha","year":"2013","journal-title":"Development"},{"issue":"6","key":"10.1016\/bs.mcb.2016.10.008_bib57","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1016\/j.cell.2014.05.010","article-title":"Development and applications of CRISPR-Cas9 for genome engineering","volume":"157","author":"Hsu","year":"2014","journal-title":"Cell"},{"issue":"8","key":"10.1016\/bs.mcb.2016.10.008_bib58","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/nbt.1939","article-title":"Heritable gene targeting in zebrafish using customized TALENs","volume":"29","author":"Huang","year":"2011","journal-title":"Nature Biotechnology"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib59","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/nbt.2501","article-title":"Efficient genome editing in zebrafish using a CRISPR-Cas system","volume":"31","author":"Hwang","year":"2013","journal-title":"Nature Biotechnology"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib60","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/ng.3465","article-title":"A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency","volume":"48","author":"Jabara","year":"2016","journal-title":"Nature Genetics"},{"issue":"34","key":"10.1016\/bs.mcb.2016.10.008_bib61","doi-asserted-by":"crossref","first-page":"13904","DOI":"10.1073\/pnas.1308335110","article-title":"Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system","volume":"110","author":"Jao","year":"2013","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"6","key":"10.1016\/bs.mcb.2016.10.008_bib62","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1128\/MCB.26.6.2419-2429.2006","article-title":"A nucleolin-binding 3\u2032 untranslated region element stabilizes beta-globin mRNA in vivo","volume":"26","author":"Jiang","year":"2006","journal-title":"Molecular and Cellular Biology"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib63","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nrm3486","article-title":"TALENs: a widely applicable technology for targeted genome editing","volume":"14","author":"Joung","year":"2013","journal-title":"Nature Reviews. Molecular Cell Biology"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib64","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.cell.2015.04.017","article-title":"Mitochondrial ClpX activates a key enzyme for heme biosynthesis and erythropoiesis","volume":"161","author":"Kardon","year":"2015","journal-title":"Cell"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib65","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.devcel.2014.11.018","article-title":"Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish","volume":"32","author":"Kok","year":"2015","journal-title":"Developmental Cell"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib66","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1056\/NEJM198407263110402","article-title":"Acquired iron-deficiency anemia caused by an antibody against the transferrin receptor","volume":"311","author":"Larrick","year":"1984","journal-title":"The New England Journal of Medicine"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib67","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/7727","article-title":"Transferrin receptor is necessary for development of erythrocytes and the nervous system","volume":"21","author":"Levy","year":"1999","journal-title":"Nature Genetics"},{"issue":"32","key":"10.1016\/bs.mcb.2016.10.008_bib68","doi-asserted-by":"crossref","first-page":"33653","DOI":"10.1074\/jbc.M403146200","article-title":"A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism","volume":"279","author":"Li","year":"2004","journal-title":"The Journal of Biological Chemistry"},{"issue":"23","key":"10.1016\/bs.mcb.2016.10.008_bib69","doi-asserted-by":"crossref","first-page":"5123","DOI":"10.1242\/dev.127.23.5123","article-title":"Hereditary spherocytosis in zebrafish riesling illustrates evolution of erythroid beta-spectrin structure, and function in red cell morphogenesis and membrane stability","volume":"127","author":"Liao","year":"2000","journal-title":"Development"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib70","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1242\/dev.129.3.649","article-title":"Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish","volume":"129","author":"Liao","year":"2002","journal-title":"Development"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib71","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12929-016-0236-5","article-title":"Zebrafish and Medaka: new model organisms for modern biomedical research","volume":"23","author":"Lin","year":"2016","journal-title":"Journal of Biomedical Science"},{"issue":"10","key":"10.1016\/bs.mcb.2016.10.008_bib72","doi-asserted-by":"crossref","first-page":"4519","DOI":"10.1073\/pnas.89.10.4519","article-title":"Production of germ-line chimeras in zebrafish by cell transplants from genetically pigmented to albino embryos","volume":"89","author":"Lin","year":"1992","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"9","key":"10.1016\/bs.mcb.2016.10.008_bib73","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.jgg.2012.07.009","article-title":"Development of novel visual-plus quantitative analysis systems for studying DNA double-strand break repairs in zebrafish","volume":"39","author":"Liu","year":"2012","journal-title":"Journal of Genetics and Genomics"},{"issue":"37","key":"10.1016\/bs.mcb.2016.10.008_bib74","doi-asserted-by":"crossref","first-page":"13612","DOI":"10.1073\/pnas.0606424103","article-title":"Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells","volume":"103","author":"Liuzzi","year":"2006","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/bs.mcb.2016.10.008_bib75","first-page":"128","article-title":"Iron, hepcidin, and the metal connection","volume":"5","author":"Loreal","year":"2014","journal-title":"Frontiers in Pharmacology"},{"issue":"8","key":"10.1016\/bs.mcb.2016.10.008_bib76","doi-asserted-by":"crossref","first-page":"5454","DOI":"10.1073\/pnas.082695299","article-title":"A nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes","volume":"99","author":"Lyons","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"5509","key":"10.1016\/bs.mcb.2016.10.008_bib77","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1126\/science.1057206","article-title":"An iron-regulated ferric reductase associated with the absorption of dietary iron","volume":"291","author":"McKie","year":"2001","journal-title":"Science"},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib78","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S1097-2765(00)80425-6","article-title":"A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation","volume":"5","author":"McKie","year":"2000","journal-title":"Molecular Cell"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib79","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1182\/blood-2004-07-2966","article-title":"Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload","volume":"105","author":"Mims","year":"2005","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2016.10.008_bib80","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.1182\/blood-2008-07-161166","article-title":"Red cell membrane: past, present, and future","volume":"112","author":"Mohandas","year":"2008","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2016.10.008_bib81","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1146\/annurev.nutr.28.061807.155521","article-title":"Systemic iron homeostasis and the iron-responsive element\/iron-regulatory protein (IRE\/IRP) regulatory network","volume":"28","author":"Muckenthaler","year":"2008","journal-title":"Annual Review of Nutrition"},{"key":"10.1016\/bs.mcb.2016.10.008_bib82","series-title":"Iron physiology and pathophysiology in humans","first-page":"27","article-title":"Cellular iron physiology","author":"Muckenthaler","year":"2012"},{"issue":"42","key":"10.1016\/bs.mcb.2016.10.008_bib83","doi-asserted-by":"crossref","first-page":"40612","DOI":"10.1074\/jbc.M307847200","article-title":"A specific role of the yeast mitochondrial carriers MRS3\/4p in mitochondrial iron acquisition under iron-limiting conditions","volume":"278","author":"M\u00fchlenhoff","year":"2003","journal-title":"The Journal of Biological Chemistry"},{"issue":"5351","key":"10.1016\/bs.mcb.2016.10.008_bib84","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1126\/science.279.5351.714","article-title":"Role of ceruloplasmin in cellular iron uptake","volume":"279","author":"Mukhopadhyay","year":"1998","journal-title":"Science"},{"issue":"5","key":"10.1016\/bs.mcb.2016.10.008_bib85","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20130078","article-title":"IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice","volume":"33","author":"Nakamura","year":"2013","journal-title":"Bioscience Reports"},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib86","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/79951","article-title":"Effective targeted gene \u2018knockdown\u2019 in zebrafish","volume":"26","author":"Nasevicius","year":"2000","journal-title":"Nature Genetics"},{"issue":"5704","key":"10.1016\/bs.mcb.2016.10.008_bib87","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1126\/science.1104742","article-title":"Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization","volume":"306","author":"Nemeth","year":"2004","journal-title":"Science"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib88","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/73480","article-title":"Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1","volume":"24","author":"Nichols","year":"2000","journal-title":"Nature Genetics"},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib89","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.cmet.2009.06.012","article-title":"Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis","volume":"10","author":"Nilsson","year":"2009","journal-title":"Cell Metabolism"},{"issue":"11","key":"10.1016\/bs.mcb.2016.10.008_bib90","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1038\/ng1658","article-title":"Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells","volume":"37","author":"Ohgami","year":"2005","journal-title":"Nature Genetics"},{"issue":"12","key":"10.1016\/bs.mcb.2016.10.008_bib91","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1242\/dev.126.12.2643","article-title":"Cell-autonomous and non-autonomous requirements for the zebrafish gene cloche in hematopoiesis","volume":"126","author":"Parker","year":"1999","journal-title":"Development"},{"issue":"12","key":"10.1016\/bs.mcb.2016.10.008_bib92","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1038\/35103567","article-title":"The art and design of genetic screens: zebrafish","volume":"2","author":"Patton","year":"2001","journal-title":"Nature Reviews. Genetics"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib93","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/ng1137","article-title":"Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency","volume":"34","author":"Paw","year":"2003","journal-title":"Nature Genetics"},{"issue":"21","key":"10.1016\/bs.mcb.2016.10.008_bib94","doi-asserted-by":"crossref","first-page":"4042","DOI":"10.1242\/dev.102186","article-title":"Making designer mutants in model organisms","volume":"141","author":"Peng","year":"2014","journal-title":"Development"},{"key":"10.1016\/bs.mcb.2016.10.008_bib95","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3389\/fphar.2014.00173","article-title":"Special delivery: distributing iron in the cytosol of mammalian cells","volume":"5","author":"Philpott","year":"2014","journal-title":"Frontiers in Pharmacology"},{"issue":"20","key":"10.1016\/bs.mcb.2016.10.008_bib96","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1056\/NEJMra1404415","article-title":"The alpha-thalassemias","volume":"371","author":"Piel","year":"2014","journal-title":"The New England Journal of Medicine"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib97","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1182\/blood.V89.1.1","article-title":"Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells","volume":"89","author":"Ponka","year":"1997","journal-title":"Blood"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib98","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/ng0498-345","article-title":"Vertebrate genome evolution and the zebrafish gene map","volume":"18","author":"Postlethwait","year":"1998","journal-title":"Nature Genetics"},{"issue":"9718","key":"10.1016\/bs.mcb.2016.10.008_bib99","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S0140-6736(09)61925-5","article-title":"Porphyrias","volume":"375","author":"Puy","year":"2010","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/bs.mcb.2016.10.008_bib100","doi-asserted-by":"crossref","first-page":"E237","DOI":"10.1371\/journal.pbio.0020237","article-title":"The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis","volume":"2","author":"Ransom","year":"2004","journal-title":"PLoS Biology"},{"key":"10.1016\/bs.mcb.2016.10.008_bib101","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1242\/dev.123.1.311","article-title":"Characterization of zebrafish mutants with defects in embryonic hematopoiesis","volume":"123","author":"Ransom","year":"1996","journal-title":"Development"},{"issue":"7611","key":"10.1016\/bs.mcb.2016.10.008_bib103","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/nature18614","article-title":"Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification","volume":"535","author":"Reischauer","year":"2016","journal-title":"Nature"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib104","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1091\/mbc.01-10-0517","article-title":"Grx5 is a mitochondrial glutaredoxin required for the activity of iron\/sulfur enzymes","volume":"13","author":"Rodriguez-Manzaneque","year":"2002","journal-title":"Molecular Biology of the Cell"},{"key":"10.1016\/bs.mcb.2016.10.008_bib105","article-title":"Microinjection of zebrafish embryos to analyze gene function","volume":"25","author":"Rosen","year":"2009","journal-title":"Journal of Visualized Experiments"},{"issue":"7564","key":"10.1016\/bs.mcb.2016.10.008_bib106","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/nature14580","article-title":"Genetic compensation induced by deleterious mutations but not gene knockdowns","volume":"524","author":"Rossi","year":"2015","journal-title":"Nature"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib107","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/nrm3909","article-title":"Mammalian iron-sulphur proteins: novel insights into biogenesis and function","volume":"16","author":"Rouault","year":"2015","journal-title":"Nature Reviews. Molecular Cell Biology"},{"issue":"7\u20138","key":"10.1016\/bs.mcb.2016.10.008_bib108","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.mod.2004.03.030","article-title":"A mutation in the gene for delta-aminolevulinic acid dehydratase (ALAD) causes hypochromic anemia in the medaka, Oryzias latipes","volume":"121","author":"Sakamoto","year":"2004","journal-title":"Mechanisms of Development"},{"issue":"18","key":"10.1016\/bs.mcb.2016.10.008_bib109","doi-asserted-by":"crossref","first-page":"4359","DOI":"10.1242\/dev.129.18.4359","article-title":"Characterization of zebrafish merlot\/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency","volume":"129","author":"Shafizadeh","year":"2002","journal-title":"Development"},{"issue":"7425","key":"10.1016\/bs.mcb.2016.10.008_bib110","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/nature11536","article-title":"Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts","volume":"491","author":"Shah","year":"2012","journal-title":"Nature"},{"issue":"7080","key":"10.1016\/bs.mcb.2016.10.008_bib111","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/nature04512","article-title":"Mitoferrin is essential for erythroid iron assimilation","volume":"440","author":"Shaw","year":"2006","journal-title":"Nature"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib112","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1182\/blood-2007-01-068148","article-title":"Direct interorganellar transfer of iron from endosome to mitochondrion","volume":"110","author":"Sheftel","year":"2007","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2016.10.008_bib113","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1146\/annurev.genom.3.031402.131506","article-title":"From zebrafish to human: modular medical models","volume":"3","author":"Shin","year":"2002","journal-title":"Annual Review of Genomics and Human Genetics"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib114","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s10534-012-9529-7","article-title":"Intracellular iron trafficking: role of cytosolic ligands","volume":"25","author":"Shvartsman","year":"2012","journal-title":"Biometals"},{"issue":"10","key":"10.1016\/bs.mcb.2016.10.008_bib116","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1242\/dev.121.10.3141","article-title":"Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages","volume":"121","author":"Stainier","year":"1995","journal-title":"Development"},{"issue":"5813","key":"10.1016\/bs.mcb.2016.10.008_bib117","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/291293a0","article-title":"Production of clones of homozygous diploid zebra fish (Brachydanio rerio)","volume":"291","author":"Streisinger","year":"1981","journal-title":"Nature"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib118","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0167-4781(99)00150-5","article-title":"Morpholino antisense oligomers: the case for an RNase H-independent structural type","volume":"1489","author":"Summerton","year":"1999","journal-title":"Biochimica et Biophysica Acta"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib119","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1101\/gr.163394.113","article-title":"Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases","volume":"24","author":"Sung","year":"2014","journal-title":"Genome Research"},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib121","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1006\/dbio.1998.8887","article-title":"The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis","volume":"197","author":"Thompson","year":"1998","journal-title":"Developmental Biology"},{"issue":"10","key":"10.1016\/bs.mcb.2016.10.008_bib122","doi-asserted-by":"crossref","first-page":"3505","DOI":"10.1182\/blood.V99.10.3505","article-title":"Regulation of ferritin genes and protein","volume":"99","author":"Torti","year":"2002","journal-title":"Blood"},{"issue":"20","key":"10.1016\/bs.mcb.2016.10.008_bib123","doi-asserted-by":"crossref","first-page":"5494","DOI":"10.1182\/blood-2010-11-319483","article-title":"Targeted deletion of the mouse mitoferrin1 gene: from anemia to protoporphyria","volume":"117","author":"Troadec","year":"2011","journal-title":"Blood"},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib124","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/5979","article-title":"Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse","volume":"21","author":"Vulpe","year":"1999","journal-title":"Nature Genetics"},{"issue":"10","key":"10.1016\/bs.mcb.2016.10.008_bib125","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1182\/blood-2007-04-086827","article-title":"Mouse\u00a0lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation","volume":"110","author":"Wang","year":"2007","journal-title":"Blood"},{"issue":"3","key":"10.1016\/bs.mcb.2016.10.008_bib126","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/3041","article-title":"A zebrafish model for hepatoerythropoietic porphyria","volume":"20","author":"Wang","year":"1998","journal-title":"Nature Genetics"},{"issue":"7","key":"10.1016\/bs.mcb.2016.10.008_bib127","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.exphem.2011.05.003","article-title":"Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria","volume":"39","author":"Wang","year":"2011","journal-title":"Experimental Hematology"},{"issue":"24","key":"10.1016\/bs.mcb.2016.10.008_bib128","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.1242\/dev.01540","article-title":"The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1","volume":"131","author":"Wingert","year":"2004","journal-title":"Development"},{"issue":"7053","key":"10.1016\/bs.mcb.2016.10.008_bib129","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1038\/nature03887","article-title":"Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis","volume":"436","author":"Wingert","year":"2005","journal-title":"Nature"},{"issue":"1","key":"10.1016\/bs.mcb.2016.10.008_bib130","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1182\/blood-2004-06-2226","article-title":"Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria","volume":"105","author":"Zhang","year":"2005","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2016.10.008_bib131","doi-asserted-by":"crossref","first-page":"124","DOI":"10.3389\/fphar.2014.00124","article-title":"The physiological functions of iron regulatory proteins in iron homeostasis \u2013 an update","volume":"5","author":"Zhang","year":"2014","journal-title":"Frontiers in Pharmacology"},{"issue":"42","key":"10.1016\/bs.mcb.2016.10.008_bib132","doi-asserted-by":"crossref","first-page":"32141","DOI":"10.1074\/jbc.M110.143248","article-title":"ZRT\/IRT-like protein 14 (ZIP14) promotes the cellular assimilation of iron from transferrin","volume":"285","author":"Zhao","year":"2010","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1016\/bs.mcb.2016.10.008_bib133","unstructured":"Zinc Finger Consortium. Available from: zincfingers.org\/default2.htm.)."},{"issue":"2","key":"10.1016\/bs.mcb.2016.10.008_bib134","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/hep.20775","article-title":"Primary iron overload with inappropriate hepcidin expression in V162del ferroportin disease","volume":"42","author":"Zoller","year":"2005","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/bs.mcb.2016.10.008_bib135","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nmeth.2374","article-title":"TALEN-mediated precise genome modification by homologous recombination in zebrafish","volume":"10","author":"Zu","year":"2013","journal-title":"Nature Methods"}],"container-title":["Methods in Cell Biology","The Zebrafish - Disease Models and Chemical Screens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091679X16301510?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091679X16301510?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:55:23Z","timestamp":1758794123000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091679X16301510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"ISBN":["9780128034736"],"references-count":133,"URL":"https:\/\/doi.org\/10.1016\/bs.mcb.2016.10.008","relation":{},"ISSN":["0091-679X"],"issn-type":[{"value":"0091-679X","type":"print"}],"subject":[],"published":{"date-parts":[[2017]]}}}