{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T11:10:05Z","timestamp":1750417805231,"version":"3.41.0"},"reference-count":28,"publisher":"Elsevier","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1016\/bs.mcb.2025.01.008","type":"book-chapter","created":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T13:22:16Z","timestamp":1740576136000},"source":"Crossref","is-referenced-by-count":0,"title":["Human and mouse iNKT cell expansion and engineering with viral vectors"],"prefix":"10.1016","author":[{"given":"Gloria","family":"Delfanti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Dellabona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Casorati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Consonni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/bs.mcb.2025.01.008_bib1","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1365-2567.2009.03130.x","article-title":"Rapid and reliable generation of invariant natural killer T-cell lines in vitro","volume":"128","author":"Chiba","year":"2009","journal-title":"Immunology"},{"key":"10.1016\/bs.mcb.2025.01.008_bib2","doi-asserted-by":"crossref","first-page":"4844","DOI":"10.1038\/s41467-021-25223-0","article-title":"Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia","volume":"12","author":"Consonni","year":"2021","journal-title":"Nature Communications"},{"key":"10.1016\/bs.mcb.2025.01.008_bib3","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1016\/j.celrep.2018.02.058","article-title":"Bimodal CD40\/Fas-dependent crosstalk between iNKT cells and tumor-associated macrophages impairs prostate cancer progression","volume":"22","author":"Cortesi","year":"2018","journal-title":"Cell Reports"},{"key":"10.1016\/bs.mcb.2025.01.008_bib4","doi-asserted-by":"crossref","first-page":"4490","DOI":"10.4049\/jimmunol.1003748","article-title":"Invariant NKT cell reconstitution in pediatric leukemia patients given HLA-haploidentical stem cell transplantation defines distinct CD4+ and CD4\u2212 subset dynamics and correlates with remission state","volume":"186","author":"De Lalla","year":"2011","journal-title":"Journal of Immunology"},{"key":"10.1016\/bs.mcb.2025.01.008_bib5","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/ni.1942","article-title":"Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A","volume":"11","author":"De Santo","year":"2010","journal-title":"Nature Immunology"},{"key":"10.1016\/bs.mcb.2025.01.008_bib6","doi-asserted-by":"crossref","first-page":"4036","DOI":"10.1172\/JCI36264","article-title":"Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans","volume":"118","author":"De Santo","year":"2008","journal-title":"The Journal of Clinical Investigation"},{"key":"10.1016\/bs.mcb.2025.01.008_bib7","doi-asserted-by":"crossref","first-page":"eabn6563","DOI":"10.1126\/sciimmunol.abn6563","article-title":"TCR-engineered iNKT cells induce robust antitumor response by dual targeting cancer and suppressive myeloid cells","volume":"7","author":"Delfanti","year":"2022","journal-title":"Science Immunology"},{"key":"10.1016\/bs.mcb.2025.01.008_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.21769\/BioProtoc.4707","article-title":"Primary mouse invariant natural killer T (iNKT) cell purification and transduction","volume":"13","author":"Delfanti","year":"2023","journal-title":"Bio-protocol"},{"key":"10.1016\/bs.mcb.2025.01.008_bib9","first-page":"1","article-title":"Purification and expansion of mouse invariant natural killer t cells for in vitro and in vivo studies","volume":"2021","author":"Delfanti","year":"2021","journal-title":"Journal of Visualized Experiments"},{"key":"10.1016\/bs.mcb.2025.01.008_bib10","first-page":"0","article-title":"An invariant Va24-JaQ\/Vb11 T cell receptor is expressed in all individuals by clonally expanded CD4-8","volume":"180","author":"Dellabona","year":"1994","journal-title":"T Cells"},{"key":"10.1016\/bs.mcb.2025.01.008_bib11","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1182\/blood-2016-11-751065","article-title":"Invariant NKT cells contribute to chronic lymphocytic leukemia surveillance and prognosis","volume":"129","author":"Gorini","year":"2017","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2025.01.008_bib12","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.immuni.2007.08.020","article-title":"Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development","volume":"27","author":"Griewank","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/bs.mcb.2025.01.008_bib13","doi-asserted-by":"crossref","DOI":"10.1038\/s41591-020-1074-2","article-title":"Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: An interim analysis","author":"Heczey","year":"2020","journal-title":"Nature Medicine"},{"key":"10.1016\/bs.mcb.2025.01.008_bib14","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1182\/blood-2013-11-541235","article-title":"Invariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy","volume":"124","author":"Heczey","year":"2014","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2025.01.008_bib786","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1038\/s41591-023-02363-y","article-title":"Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results","volume":"29","author":"Heczey","year":"2023","journal-title":"Nat. Med."},{"key":"10.1016\/bs.mcb.2025.01.008_bib15","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/imm.12746","article-title":"Loss of natural killer T cells promotes pancreatic cancer in LSL-KrasG12D\/+ mice","volume":"152","author":"Janakiram","year":"2017","journal-title":"Immunology"},{"key":"10.1016\/bs.mcb.2025.01.008_bib16","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1158\/2326-6066.CIR-19-0134","article-title":"A high-avidity T-cell receptor redirects natural killer T-cell specificity and outcompetes the endogenous invariant T-cell receptor","volume":"8","author":"Landoni","year":"2020","journal-title":"Cancer Immunology Research"},{"key":"10.1016\/bs.mcb.2025.01.008_bib17","first-page":"1","article-title":"IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity","volume":"15","author":"Landoni","year":"2024","journal-title":"Nature Communications."},{"key":"10.1016\/bs.mcb.2025.01.008_bib18","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1084\/jem.180.3.1097","article-title":"An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans","volume":"180","author":"Lantz","year":"1994","journal-title":"The Journal of Experimental Medicine"},{"key":"10.1016\/bs.mcb.2025.01.008_bib19","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1172\/JCI59535","article-title":"IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity","volume":"122","author":"Liu","year":"2012","journal-title":"The Journal of Clinical Investigation"},{"key":"10.1016\/bs.mcb.2025.01.008_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1084\/jem.178.1.1","article-title":"Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha\/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain","volume":"178","author":"Porcelli","year":"1993","journal-title":"The Journal of Experimental Medicine"},{"key":"10.1016\/bs.mcb.2025.01.008_bib21","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1182\/blood-2021-149712","article-title":"Allogeneic NKT cells expressing a CD19-specific CAR in patients with relapsed or refractory B-cell malignancies: An interim analysis","volume":"138","author":"Ramos","year":"2021","journal-title":"Blood"},{"key":"10.1016\/bs.mcb.2025.01.008_bib22","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.ccell.2018.08.017","article-title":"Enhanced anti-lymphoma activity of CAR19-iNKT cells underpinned by dual CD19 and CD1d targeting","volume":"34","author":"Rotolo","year":"2018","journal-title":"Cancer Cell"},{"key":"10.1016\/bs.mcb.2025.01.008_bib23","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/leu.2016.281","article-title":"Pre-transplant donor CD4 - Invariant NKT cell expansion capacity predicts the occurrence of acute graft-versus-host disease","volume":"31","author":"Rubio","year":"2017","journal-title":"Leukemia"},{"key":"10.1016\/bs.mcb.2025.01.008_bib24","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1172\/JCI37869","article-title":"Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages","volume":"119","author":"Song","year":"2009","journal-title":"The Journal of Clinical Investigation"},{"key":"10.1016\/bs.mcb.2025.01.008_bib25","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1172\/JCI83476","article-title":"CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo","volume":"126","author":"Tian","year":"2016","journal-title":"The Journal of Clinical Investigation"},{"key":"10.1016\/bs.mcb.2025.01.008_bib26","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nprot.2007.515","article-title":"Methods for detection, isolation and culture of mouse and human invariant NKT cells","volume":"3","author":"Watarai","year":"2008","journal-title":"Nature Protocols"},{"key":"10.1016\/bs.mcb.2025.01.008_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.00384","article-title":"Novel approaches to exploiting invariant NKT cells in cancer immunotherapy","volume":"9","author":"Wolf","year":"2018","journal-title":"Frontiers in Immunology"}],"container-title":["Methods in Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091679X25000299?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091679X25000299?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T10:34:13Z","timestamp":1750415653000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091679X25000299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":28,"URL":"https:\/\/doi.org\/10.1016\/bs.mcb.2025.01.008","relation":{},"ISSN":["0091-679X"],"issn-type":[{"type":"print","value":"0091-679X"}],"subject":[],"published":{"date-parts":[[2025]]}}}