{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:16:49Z","timestamp":1790194609538,"version":"4.1.0"},"reference-count":21,"publisher":"Elsevier","isbn-type":[{"value":"9780443430619","type":"print"}],"license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["25299"],"award-info":[{"award-number":["25299"]}],"id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/bs.mcb.2025.10.014","type":"book-chapter","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T12:19:47Z","timestamp":1764245987000},"page":"1-16","source":"Crossref","is-referenced-by-count":1,"title":["In situ imaging of pulmonary invariant Natural Killer T cells in precision cut lung slices"],"prefix":"10.1016","author":[{"given":"Tom","family":"Langelaar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin E.","family":"de Visser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Burrello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/bs.mcb.2025.10.014_bib1","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1016\/j.immuni.2022.07.019","article-title":"Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes","volume":"55","author":"Ataide","year":"2022","journal-title":"Immunity"},{"key":"10.1016\/bs.mcb.2025.10.014_bib2","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1158\/2326-6066.CIR-21-0445","article-title":"Imaging \u03b1-GalCer\u2013activated iNKT cells in a hepatic metastatic environment","volume":"10","author":"Babes","year":"2022","journal-title":"Cancer Immunology Research"},{"key":"10.1016\/bs.mcb.2025.10.014_bib3","doi-asserted-by":"crossref","first-page":"2378","DOI":"10.1038\/emboj.2012.87","article-title":"The location of splenic NKT cells favours their rapid activation by blood\u2010borne antigen","volume":"31","author":"Barral","year":"2012","journal-title":"The EMBO Journal"},{"key":"10.1016\/bs.mcb.2025.10.014_bib4","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.immuni.2006.06.017","article-title":"Granulocyte-macrophage colony-stimulating factor regulates effector differentiation of invariant natural killer T cells during thymic ontogeny","volume":"25","author":"Bezbradica","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/bs.mcb.2025.10.014_bib5","first-page":"101","article-title":"Invariant natural killer T cells: An innate activation scheme linked to diverse effector functions","volume":"13","author":"Brennan","year":"2013","journal-title":"Nature Reviews\u00a0Immunology"},{"key":"10.1016\/bs.mcb.2025.10.014_bib6","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1093\/ecco-jcc\/jjac049","article-title":"IL10 secretion endows intestinal human iNKT cells with regulatory functions towards pathogenic T lymphocytes","volume":"16","author":"Burrello","year":"2022","journal-title":"Journal of Crohn\u2019s and Colitis"},{"key":"10.1016\/bs.mcb.2025.10.014_bib7","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/ni.3203","article-title":"A new mouse strain for the analysis of invariant NKT cell function","volume":"16","author":"Chandra","year":"2015","journal-title":"Nature Immunology"},{"key":"10.1016\/bs.mcb.2025.10.014_bib8","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1016\/j.celrep.2018.02.058","article-title":"Bimodal CD40\/fas-dependent crosstalk between iNKT cells and tumor-associated macrophages impairs prostate cancer progression","volume":"22","author":"Cortesi","year":"2018","journal-title":"Cell Reports"},{"key":"10.1016\/bs.mcb.2025.10.014_bib9","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.3389\/fimmu.2018.02375","article-title":"The pathophysiological relevance of the iNKT cell\/mononuclear phagocyte crosstalk in tissues","volume":"9","author":"Cortesi","year":"2018","journal-title":"Frontiers in Immunology"},{"key":"10.1016\/bs.mcb.2025.10.014_bib10","first-page":"559","article-title":"Tissue-specific functions of invariant natural killer T cells","volume":"18","author":"Crosby","year":"2018","journal-title":"Nature Reviews\u00a0Immunology"},{"key":"10.1016\/bs.mcb.2025.10.014_bib11","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/ni.1942","article-title":"Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A","volume":"11","author":"De Santo","year":"2010","journal-title":"Nature Immunology"},{"key":"10.1016\/bs.mcb.2025.10.014_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/1878-0261.13104","article-title":"Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal cancer cells via the perforin\u2013granzyme pathway","author":"D\u00edaz-Basabe","year":"2021","journal-title":"Molecular Oncology"},{"key":"10.1016\/bs.mcb.2025.10.014_bib13","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1038\/d41586-021-01396-y","article-title":"Tissues, not blood, are where immune cells function","volume":"593","author":"Farber","year":"2021","journal-title":"Nature"},{"key":"10.1016\/bs.mcb.2025.10.014_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.0030113","article-title":"Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids","volume":"3","author":"Geissmann","year":"2005","journal-title":"PLoS Biology"},{"key":"10.1016\/bs.mcb.2025.10.014_bib15","doi-asserted-by":"crossref","first-page":"4034","DOI":"10.1038\/s41598-022-07704-4","article-title":"Differential location of NKT and MAIT cells within lymphoid tissue","volume":"12","author":"Johnson","year":"2022","journal-title":"Scientific Reports"},{"key":"10.1016\/bs.mcb.2025.10.014_bib16","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.76586","article-title":"Longitudinal analysis of invariant natural killer T cell activation reveals a cMAF-associated transcriptional state of NKT10 cells","volume":"11","author":"Kane","year":"2022","journal-title":"Elife"},{"key":"10.1016\/bs.mcb.2025.10.014_bib17","series-title":"Asthma: Methods and\u00a0protocols","article-title":"Human precision-cut lung slices: Generation of and measurement of contractility and relaxation of small airways","author":"Koziol-White","year":"2022"},{"key":"10.1016\/bs.mcb.2025.10.014_bib18","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/ni.3047","article-title":"Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue","volume":"16","author":"Lynch","year":"2015","journal-title":"Nature Immunology"},{"key":"10.1016\/bs.mcb.2025.10.014_bib19","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1038\/s41467-021-21574-w","article-title":"Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure","volume":"12","author":"Murray","year":"2021","journal-title":"Nature Communications"},{"key":"10.1016\/bs.mcb.2025.10.014_bib20","doi-asserted-by":"crossref","first-page":"3260","DOI":"10.1016\/j.celrep.2016.07.052","article-title":"iNKT Cell emigration out of the lung vasculature requires neutrophils and monocyte-derived dendritic cells in inflammation","volume":"16","author":"Thanabalasuriar","year":"2016","journal-title":"Cell Reports"},{"key":"10.1016\/bs.mcb.2025.10.014_bib21","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.4049\/jimmunol.1001018","article-title":"Antigen-specific cytotoxicity by invariant NKT cells in vivo Is CD95\/CD178-dependent and is correlated with antigenic potency","volume":"185","author":"Wingender","year":"2010","journal-title":"The Journal of Immunology"}],"container-title":["Methods in Cell Biology","Immuno-Oncology and Immunotherapy Part - G"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091679X25002225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091679X25002225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T14:00:56Z","timestamp":1770818456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091679X25002225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"ISBN":["9780443430619"],"references-count":21,"URL":"https:\/\/doi.org\/10.1016\/bs.mcb.2025.10.014","relation":{},"ISSN":["0091-679X"],"issn-type":[{"value":"0091-679X","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]}}}