{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T21:40:17Z","timestamp":1758750017859,"version":"3.44.0"},"reference-count":24,"publisher":"Elsevier","isbn-type":[{"type":"print","value":"9780128186732"}],"license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020]]},"DOI":"10.1016\/bs.mie.2019.05.035","type":"book-chapter","created":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T08:04:20Z","timestamp":1564646660000},"page":"443-466","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of cancer cell-intrinsic immune regulation in response to CD8 + T cell attack"],"prefix":"10.1016","member":"78","reference":[{"issue":"5","key":"10.1016\/bs.mie.2019.05.035_bb0010","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1073\/pnas.0510454103","article-title":"Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure","volume":"103","author":"Abouzahr","year":"2006","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"4","key":"10.1016\/bs.mie.2019.05.035_bb0015","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.4049\/jimmunol.130.4.1492","article-title":"Recombinant interferon-gamma increases HLA-DR synthesis and expression","volume":"130","author":"Basham","year":"1983","journal-title":"Journal of Immunology (Baltimore, Md: 1950)"},{"issue":"11","key":"10.1016\/bs.mie.2019.05.035_bb0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049010","article-title":"Using digital RNA counting and flow cytometry to compare mRNA with protein expression in acute leukemias","volume":"7","author":"Fernandez","year":"2012","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/bs.mie.2019.05.035_bb0025","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1586\/14737140.7.9.1255","article-title":"Inhibitor of apoptosis proteins as targets for anticancer therapy","volume":"7","author":"Fulda","year":"2007","journal-title":"Expert Review of Anticancer Therapy"},{"issue":"3","key":"10.1016\/bs.mie.2019.05.035_bb0030","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nbt1385","article-title":"Direct multiplexed measurement of gene expression with color-coded probe pairs","volume":"26","author":"Geiss","year":"2008","journal-title":"Nature Biotechnology"},{"issue":"5","key":"10.1016\/bs.mie.2019.05.035_bb0035","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/nrclinonc.2016.25","article-title":"The future of cancer treatment: Immunomodulation, CARs and combination immunotherapy","volume":"13","author":"Khalil","year":"2016","journal-title":"Nature Reviews Clinical Oncology"},{"key":"10.1016\/bs.mie.2019.05.035_bb0040","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/nature11538","article-title":"Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation","volume":"490","author":"Landsberg","year":"2012","journal-title":"Nature"},{"issue":"1","key":"10.1016\/bs.mie.2019.05.035_bb0045","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/BF01788956","article-title":"Interferons up-regulate with different potency HLA class I antigen expression in M14 human melanoma cell line. Possible interaction with glucocorticoid hormones","volume":"41","author":"Lanza","year":"1995","journal-title":"Cancer Immunology, Immunotherapy: CII"},{"issue":"6","key":"10.1016\/bs.mie.2019.05.035_bb0050","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1007\/s00262-011-1140-1","article-title":"Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose","volume":"61","author":"L\u00f6vgren","year":"2012","journal-title":"Cancer Immunology, Immunotherapy: CII"},{"issue":"4","key":"10.1016\/bs.mie.2019.05.035_bb0055","doi-asserted-by":"crossref","first-page":"467","DOI":"10.4161\/onci.19856","article-title":"Human melanoma-specific CD8(+) T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo","volume":"1","author":"Mahnke","year":"2012","journal-title":"Oncoimmunology"},{"issue":"1","key":"10.1016\/bs.mie.2019.05.035_bb0060","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/mt.2013.255","article-title":"Immunotherapy-induced CD8+ T cells instigate immune suppression in the tumor","volume":"22","author":"McGray","year":"2013","journal-title":"Molecular Therapy: the Journal of the American Society of Gene Therapy"},{"issue":"436","key":"10.1016\/bs.mie.2019.05.035_bb0065","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aan3311","article-title":"T cell-induced CSF1 promotes melanoma resistance to PD1 blockade","volume":"10","author":"Neubert","year":"2018","journal-title":"Science Translational Medicine"},{"key":"10.1016\/bs.mie.2019.05.035_bb0070","doi-asserted-by":"crossref","first-page":"326","DOI":"10.3389\/fimmu.2016.00326","article-title":"A well-controlled experimental system to study interactions of cytotoxic T lymphocytes with tumor cells","volume":"7","author":"Neubert","year":"2016","journal-title":"Frontiers in Immunology"},{"issue":"7","key":"10.1016\/bs.mie.2019.05.035_bb0075","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1158\/0008-5472.CAN-16-2680","article-title":"Broad and conserved immune regulation by genetically heterogeneous melanoma cells","volume":"77","author":"Neubert","year":"2017","journal-title":"Cancer Research"},{"issue":"6382","key":"10.1016\/bs.mie.2019.05.035_bb0080","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1126\/science.aar4060","article-title":"Cancer immunotherapy using checkpoint blockade","volume":"359","author":"Ribas","year":"2018","journal-title":"Science (New York, N.Y.)"},{"issue":"6230","key":"10.1016\/bs.mie.2019.05.035_bb0085","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1126\/science.aaa4967","article-title":"Adoptive cell transfer as personalized immunotherapy for human cancer","volume":"348","author":"Rosenberg","year":"2015","journal-title":"Science (New York, N.Y.)"},{"issue":"2","key":"10.1016\/bs.mie.2019.05.035_bb0090","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/jid.2011.305","article-title":"Review and cross-validation of gene expression signatures and melanoma prognosis","volume":"132","author":"Schramm","year":"2011","journal-title":"Journal of Investigative Dermatology"},{"issue":"6230","key":"10.1016\/bs.mie.2019.05.035_bb0095","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1126\/science.aaa8172","article-title":"The future of immune checkpoint therapy","volume":"348","author":"Sharma","year":"2015","journal-title":"Science (New York, N.Y.)"},{"issue":"2","key":"10.1016\/bs.mie.2019.05.035_bb0100","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1158\/2159-8290.CD-16-1223","article-title":"Primary resistance to PD-1 blockade mediated by JAK1\/2 mutations","volume":"7","author":"Shin","year":"2017","journal-title":"Cancer Discovery"},{"issue":"2","key":"10.1016\/bs.mie.2019.05.035_bb0105","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.4049\/jimmunol.177.2.1338","article-title":"A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: Spontaneous priming and efficient boosting by vaccination","volume":"177","author":"Speiser","year":"2006","journal-title":"Journal of Immunology (Baltimore, Md: 1950)"},{"issue":"10","key":"10.1016\/bs.mie.2019.05.035_bb0110","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1073\/pnas.0800080105","article-title":"Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen","volume":"105","author":"Speiser","year":"2008","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"127","key":"10.1016\/bs.mie.2019.05.035_bb0115","doi-asserted-by":"crossref","first-page":"127ra37","DOI":"10.1126\/scitranslmed.3003689","article-title":"Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape","volume":"4","author":"Taube","year":"2012","journal-title":"Science Translational Medicine"},{"issue":"7528","key":"10.1016\/bs.mie.2019.05.035_bb0120","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/nature13954","article-title":"PD-1 blockade induces responses by inhibiting adaptive immune resistance","volume":"515","author":"Tumeh","year":"2014","journal-title":"Nature"},{"issue":"13","key":"10.1016\/bs.mie.2019.05.035_bb0125","first-page":"2835","article-title":"Mutations associated with acquired resistance to PD-1 blockade in melanoma","volume":"375","author":"Zaretsky","year":"2016","journal-title":"The New England Journal of Medicine"}],"container-title":["Methods in Enzymology","Tumor Immunology and Immunotherapy \u2013 Cellular Methods Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0076687919302058?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0076687919302058?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T21:26:40Z","timestamp":1758749200000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0076687919302058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"ISBN":["9780128186732"],"references-count":24,"URL":"https:\/\/doi.org\/10.1016\/bs.mie.2019.05.035","relation":{},"ISSN":["0076-6879"],"issn-type":[{"type":"print","value":"0076-6879"}],"subject":[],"published":{"date-parts":[[2020]]}}}