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Lett."},{"issue":"10","key":"10.1016\/bs.pbr.2020.09.012_bb0330","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.1089\/ten.tea.2008.0506","article-title":"Linear ordered collagen scaffolds loaded with collagen-binding brain-derived neurotrophic factor improve the recovery of spinal cord injury in rats","volume":"15","author":"Han","year":"2009","journal-title":"Tissue Eng. Part A"},{"issue":"3","key":"10.1016\/bs.pbr.2020.09.012_bb0335","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.neulet.2010.09.007","article-title":"Simvastatin treatment improves functional recovery after experimental spinal cord injury by upregulating the expression of BDNF and GDNF","volume":"487","author":"Han","year":"2011","journal-title":"Neurosci. Lett."},{"issue":"3","key":"10.1016\/bs.pbr.2020.09.012_bb0340","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0940-9602(03)80030-4","article-title":"Rescue of rat spinal motoneurons from avulsion-induced cell death by intrathecal administration of IGF-I and Cerebrolysin","volume":"185","author":"Haninec","year":"2003","journal-title":"Ann. Anat."},{"issue":"4","key":"10.1016\/bs.pbr.2020.09.012_bb0345","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00221-004-1969-z","volume":"159","author":"Haninec","year":"2004","journal-title":"Exp. 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Pathol."},{"issue":"6","key":"10.1016\/bs.pbr.2020.09.012_bb0490","doi-asserted-by":"crossref","first-page":"062002","DOI":"10.1088\/0957-4484\/26\/6\/062002","article-title":"Titanium nanostructures for biomedical applications","volume":"26","author":"Kulkarni","year":"2015","journal-title":"Nanotechnology"},{"issue":"5","key":"10.1016\/bs.pbr.2020.09.012_bb0495","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/0092-8674(91)90442-2","article-title":"trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3","volume":"66","author":"Lamballe","year":"1991","journal-title":"Cell"},{"issue":"5","key":"10.1016\/bs.pbr.2020.09.012_bb0500","first-page":"1063","article-title":"Nerve growth factor promotes corneal healing: structural, biochemical, and molecular analyses of rat and human corneas","volume":"41","author":"Lambiase","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/bs.pbr.2020.09.012_bb0505","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1523\/JNEUROSCI.17-03-01137.1997","article-title":"Differential regulation of ciliary neurotrophic factor (CNTF) and CNTF receptor alpha expression in astrocytes and neurons of the fascia dentata after entorhinal cortex lesion","volume":"17","author":"Lee","year":"1997","journal-title":"J. Neurosci."},{"issue":"7124","key":"10.1016\/bs.pbr.2020.09.012_bb0510","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nature05453","article-title":"Genome-wide atlas of gene expression in the adult mouse brain","volume":"445","author":"Lein","year":"2007","journal-title":"Nature"},{"issue":"2","key":"10.1016\/bs.pbr.2020.09.012_bb0515","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/jez.1401160206","article-title":"Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo","volume":"116","author":"Levi-Montalcini","year":"1951","journal-title":"J. Exp. Zool."},{"issue":"7","key":"10.1016\/bs.pbr.2020.09.012_bb0520","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1002\/neu.480250702","article-title":"Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse","volume":"25","author":"Li","year":"1994","journal-title":"J. Neurobiol."},{"issue":"27","key":"10.1016\/bs.pbr.2020.09.012_bb0525","doi-asserted-by":"crossref","first-page":"4708","DOI":"10.1016\/j.biomaterials.2009.05.015","article-title":"The incorporation of daunorubicin in cancer cells through the use of titanium dioxide whiskers","volume":"30","author":"Li","year":"2009","journal-title":"Biomaterials"},{"issue":"5111","key":"10.1016\/bs.pbr.2020.09.012_bb0530","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1126\/science.8493557","article-title":"GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons","volume":"260","author":"Lin","year":"1993","journal-title":"Science"},{"issue":"1","key":"10.1016\/bs.pbr.2020.09.012_bb0535","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0169-328X(97)00367-7","article-title":"Differential regulation of ciliary neurotrophic factor (CNTF) and CNTF receptor alpha (CNTFR alpha) expression following focal cerebral ischemia","volume":"55","author":"Lin","year":"1998","journal-title":"Brain Res. 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Rev."},{"issue":"23","key":"10.1016\/bs.pbr.2020.09.012_bb0550","doi-asserted-by":"crossref","first-page":"19687","DOI":"10.1074\/jbc.M112.350934","article-title":"Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress","volume":"287","author":"Liu","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/bs.pbr.2020.09.012_bb0555","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.optmat.2006.03.033","article-title":"Synthesis of TiO2 nanostructured reservoir with temozolomide: structural evolution of the occluded drug","volume":"29","author":"Lopez","year":"2006","journal-title":"Opt. Mater."},{"issue":"4","key":"10.1016\/bs.pbr.2020.09.012_bb0560","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/cne.1080","article-title":"Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons","volume":"436","author":"Lu","year":"2001","journal-title":"J. Comp. Neurol."},{"issue":"6","key":"10.1016\/bs.pbr.2020.09.012_bb0565","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.cell.2012.03.050","article-title":"A thrombospondin-dependent pathway for a protective ER stress response","volume":"149","author":"Lynch","year":"2012","journal-title":"Cell"},{"issue":"2","key":"10.1016\/bs.pbr.2020.09.012_bb0570","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3727\/096368910X492634","article-title":"Effect of neurotrophin-3 genetically modified olfactory ensheathing cells transplantation on spinal cord injury","volume":"19","author":"Ma","year":"2010","journal-title":"Cell Transplant."},{"issue":"2","key":"10.1016\/bs.pbr.2020.09.012_bb0575","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1523\/JNEUROSCI.16-02-00621.1996","article-title":"Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system","volume":"16","author":"MacLennan","year":"1996","journal-title":"J. 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A."},{"issue":"4","key":"10.1016\/bs.pbr.2020.09.012_bb0590","first-page":"191","article-title":"Programmed cell life: anti-apoptotic signaling and therapeutic strategies for neurodegenerative disorders","volume":"9","author":"Mattson","year":"1996","journal-title":"Restor. Neurol. Neurosci."},{"key":"10.1016\/bs.pbr.2020.09.012_bb0595","unstructured":"Menon, P.K., 2011. Effects of Cerebrolysin, a mixture of neurotrophins on spinal cord injury in relation to nanoparticles treatment. Master's Thesis, Uppsala University, Biotechnology Program (Supervisor: Hari S Sharma), Uppsala, Sweden, pp. 1\u201328. 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