{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:29:13Z","timestamp":1786123753939,"version":"build-2736575974"},"reference-count":254,"publisher":"Elsevier","isbn-type":[{"value":"9780323989275","type":"print"}],"license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AG028679"],"award-info":[{"award-number":["R01 AG028679"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003086","name":"Eusko Jaurlaritza","doi-asserted-by":"publisher","award":["CS-2203"],"award-info":[{"award-number":["CS-2203"]}],"id":[{"id":"10.13039\/501100003086","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000181","name":"Air Force Office of Scientific Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000181","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003426","name":"G\u00f6ran Gustafssons Stiftelse f\u00f6r Naturvetenskaplig och Medicinsk Forskning","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003426","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000957","name":"Alzheimer's Association","doi-asserted-by":"publisher","award":["IIRG-09-132087"],"award-info":[{"award-number":["IIRG-09-132087"]}],"id":[{"id":"10.13039\/100000957","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003451","name":"Euskal Herriko Unibertsitatea","doi-asserted-by":"publisher","award":["14\/08"],"award-info":[{"award-number":["14\/08"]}],"id":[{"id":"10.13039\/501100003451","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010009","name":"Edge Hill University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015464","name":"European Office of Aerospace Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015464","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019473","name":"Ministry of Science and Technology, Pakistan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019473","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006310","name":"Medicinska Forskningsr\u00e5det","doi-asserted-by":"publisher","award":["Nr 2710-HSS"],"award-info":[{"award-number":["Nr 2710-HSS"]}],"id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006394","name":"Air Force Materiel Command","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006394","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009928","name":"Higher Committee for Education Development in Iraq","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009928","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006831","name":"U.S. Air Force","doi-asserted-by":"publisher","award":["FA8655-05-1-3065"],"award-info":[{"award-number":["FA8655-05-1-3065"]}],"id":[{"id":"10.13039\/100006831","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015991","name":"Middle Technical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015991","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.1016\/bs.pbr.2021.06.016","type":"book-chapter","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T14:43:45Z","timestamp":1634827425000},"page":"211-212","source":"Crossref","is-referenced-by-count":16,"title":["REMOVED: Cerebrolysin restores balance between excitatory and inhibitory amino acids in brain following concussive head injury. Superior neuroprotective effects of TiO2 nanowired drug delivery"],"prefix":"10.1016","author":[{"given":"Hari Shanker","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dafin F.","family":"Muresanu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seaab","family":"Sahib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z. Ryan","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Vicente","family":"Lafuente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca D.","family":"Buzoianu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ala","family":"Nozari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiquiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Wiklund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aruna","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb0010","doi-asserted-by":"crossref","first-page":"756","DOI":"10.4085\/1062-6050-220-17","article-title":"Assessment of evidence-based health and safety policies on sudden death and concussion management in secondary school athletics: a benchmark study","volume":"53","author":"Adams","year":"2018","journal-title":"J. Athl. Train."},{"issue":"5\u20136","key":"10.1016\/bs.pbr.2021.06.016_bb0015","doi-asserted-by":"crossref","first-page":"e233","DOI":"10.1093\/milmed\/usy313","article-title":"Incidence of traumatic brain injury in the U.S. military, 2010-2014","volume":"184","author":"Agimi","year":"2019","journal-title":"Mil. Med."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0020","doi-asserted-by":"crossref","first-page":"26009","DOI":"10.1088\/1741-2560\/7\/2\/026009","article-title":"Local glutamate release in the rat ventral lateral thalamus evoked by high-frequency stimulation","volume":"7","author":"Agnesi","year":"2010","journal-title":"J. Neural Eng."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0025","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S0361-9230(01)00775-4","article-title":"Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease","volume":"57","author":"Alberch","year":"2002","journal-title":"Brain Res. Bull."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0030","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.expneurol.2015.07.028","article-title":"GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury","volume":"273","author":"Almeida-Suhett","year":"2015","journal-title":"Exp. Neurol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0035","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1089\/neu.2000.17.31","article-title":"Extracellular N-acetyl-aspartate as a biochemical marker of the severity of neuronal damage following experimental acute traumatic brain injury","volume":"17","author":"Al-Samsam","year":"2000","journal-title":"J. Neurotrauma"},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0040","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.pmr.2016.12.008","article-title":"Unique aspects of traumatic brain injury in military and veteran populations","volume":"28","author":"Armistead-Jehle","year":"2017","journal-title":"Phys. Med. Rehabil. Clin. N. Am."},{"issue":"12","key":"10.1016\/bs.pbr.2021.06.016_bb0045","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/S1474-4422(16)30230-7","article-title":"The epidemiology of Parkinson's disease: risk factors and prevention","volume":"15","author":"Ascherio","year":"2016","journal-title":"Lancet Neurol."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0050","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s11682-017-9708-9","article-title":"Diffusion tensor imaging (DTI) findings in adult civilian, military, and sport-related mild traumatic brain injury (mTBI): a systematic critical review","volume":"12","author":"Asken","year":"2018","journal-title":"Brain Imaging Behav."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0055","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/00006534-198901000-00024","article-title":"Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat","volume":"83","author":"Bain","year":"1989","journal-title":"Plast. Reconstr. Surg."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0060","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1111\/j.1471-4159.1991.tb08303.x","article-title":"Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain","volume":"57","author":"Baker","year":"1991","journal-title":"J. Neurochem."},{"issue":"10","key":"10.1016\/bs.pbr.2021.06.016_bb0065","doi-asserted-by":"crossref","first-page":"961","DOI":"10.2174\/156802606777323700","article-title":"Trophic effect of glutamate","volume":"6","author":"Balazs","year":"2006","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0070","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/B978-0-444-63954-7.00007-0","article-title":"Epidemiology of sports concussion in the United States","volume":"158","author":"Baldwin","year":"2018","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0075","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1023\/A:1023250721185","article-title":"N-acetylaspartate in the vertebrate brain: metabolism and function","volume":"28","author":"Baslow","year":"2003","journal-title":"Neurochem. Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0080","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1111\/j.1471-4159.2005.03602.x","article-title":"Extracellular N-acetylaspartate depletion in traumatic brain injury","volume":"96","author":"Belli","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0085","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3389\/fncel.2020.00051","article-title":"Ischemia-triggered glutamate excitotoxicity from the perspective of glial cells","volume":"14","author":"Belov Kirdajova","year":"2020","journal-title":"Front. Cell. Neurosci."},{"issue":"16","key":"10.1016\/bs.pbr.2021.06.016_bb0090","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1212\/WNL.0000000000003852","article-title":"Mild traumatic brain injury in soldiers returning from combat","volume":"88","author":"Bigler","year":"2017","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0095","doi-asserted-by":"crossref","first-page":"e42","DOI":"10.1097\/JSA.0000000000000119","article-title":"Structural neuroimaging findings in mild traumatic brain injury","volume":"24","author":"Bigler","year":"2016","journal-title":"Sports Med. Arthrosc. Rev."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0100","doi-asserted-by":"crossref","first-page":"16084","DOI":"10.1038\/nrdp.2016.84","article-title":"Traumatic brain injuries","volume":"2","author":"Blennow","year":"2016","journal-title":"Nat. Rev. Dis. Primers."},{"issue":"11","key":"10.1016\/bs.pbr.2021.06.016_bb0105","doi-asserted-by":"crossref","first-page":"3089","DOI":"10.1097\/CCM.0b013e31818bd7df","article-title":"Cerebral blood flow thresholds for cerebral ischemia in traumatic brain injury. A systematic review","volume":"36","author":"Botteri","year":"2008","journal-title":"Crit. Care Med."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0110","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/JSA.0000000000000111","article-title":"Mild traumatic brain injury and post-concussion syndrome: treatment and related sequela for persistent symptomatic disease","volume":"24","author":"Bramley","year":"2016","journal-title":"Sports Med. Arthrosc. Rev."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0115","doi-asserted-by":"crossref","first-page":"228","DOI":"10.3109\/02699052.2014.974674","article-title":"A review of post-concussion syndrome and psychological factors associated with concussion","volume":"29","author":"Broshek","year":"2015","journal-title":"Brain Inj."},{"issue":"12","key":"10.1016\/bs.pbr.2021.06.016_bb0120","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.3109\/02699052.2013.823651","article-title":"Multiple traumatic brain injury and concussive symptoms among deployed military personnel","volume":"27","author":"Bryan","year":"2013","journal-title":"Brain Inj."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0125","doi-asserted-by":"crossref","first-page":"3192","DOI":"10.1073\/pnas.1906369117","article-title":"GABA-mediated tonic inhibition differentially modulates gain in functional subtypes of cortical interneurons","volume":"117","author":"Bryson","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0130","doi-asserted-by":"crossref","first-page":"4248529","DOI":"10.1155\/2019\/4248529","article-title":"Glycine protects against hypoxic-ischemic brain injury by regulating mitochondria-mediated autophagy via the AMPK pathway","volume":"2019","author":"Cai","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb0135","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.jpain.2018.11.014","article-title":"Imbalance between excitatory and inhibitory synaptic transmission in the primary somatosensory cortex caused by persistent nociception in rats","volume":"20","author":"Cao","year":"2019","journal-title":"J. Pain"},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0140","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1111\/j.1471-4159.2009.06187.x","article-title":"L-aspartate as an amino acid neurotransmitter: mechanisms of the depolarization-induced release from cerebrocortical synaptosomes","volume":"110","author":"Cavallero","year":"2009","journal-title":"J. Neurochem."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0145","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0079-6123(08)62039-7","article-title":"Glial reactions in the central nervous system following heat stress","volume":"115","author":"Cerv\u00f3s-Navarro","year":"1998","journal-title":"Prog. Brain Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0150","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1046\/j.1471-4159.2001.00456.x","article-title":"Intraneuronal N-acetylaspartate supplies acetyl groups for myelin lipid synthesis: evidence for myelin-associated aspartoacylase","volume":"78","author":"Chakraborty","year":"2001","journal-title":"J. Neurochem."},{"issue":"10","key":"10.1016\/bs.pbr.2021.06.016_bb0155","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1113\/jphysiol.2014.271700","article-title":"Activation of glycine receptors modulates spontaneous epileptiform activity in the immature rat hippocampus","volume":"592","author":"Chen","year":"2014","journal-title":"J. Physiol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0160","doi-asserted-by":"crossref","first-page":"4028394","DOI":"10.1155\/2019\/4028394","article-title":"The roles of GABA in ischemia-reperfusion injury in the central nervous system and peripheral organs","volume":"2019","author":"Chen","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"10","key":"10.1016\/bs.pbr.2021.06.016_bb0165","first-page":"6895","article-title":"Glycine attenuates cerebrovascular remodeling via glycine receptor alpha 2 and vascular endothelial growth factor receptor 2 after stroke","volume":"12","author":"Chen","year":"2020","journal-title":"Am. J. Transl. Res."},{"issue":"20","key":"10.1016\/bs.pbr.2021.06.016_bb0170","doi-asserted-by":"crossref","first-page":"4829","DOI":"10.1523\/JNEUROSCI.2731-17.2018","article-title":"Altered excitability and local connectivity of mPFC-PAG neurons in a mouse model of neuropathic pain","volume":"38","author":"Cheriyan","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0175","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.neuint.2018.08.003","article-title":"Early behavioral and metabolomic change after mild to moderate traumatic brain injury in the developing brain","volume":"120","author":"Chitturi","year":"2018","journal-title":"Neurochem. Int."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0180","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s11916-016-0573-9","article-title":"The pathophysiology of concussion","volume":"20","author":"Choe","year":"2016","journal-title":"Curr. Pain Headache Rep."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0185","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0304-3940(91)90465-6","article-title":"Uptake of glycine, GABA and glutamate by synaptic vesicles isolated from different regions of rat CNS","volume":"129","author":"Christensen","year":"1991","journal-title":"Neurosci. Lett."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0190","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1096\/fj.10-168492","article-title":"D-aspartic acid is a novel endogenous neurotransmitter","volume":"25","author":"D'Aniello","year":"2011","journal-title":"FASEB J."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0195","doi-asserted-by":"crossref","first-page":"E5","DOI":"10.3171\/2012.10.FOCUS12284","article-title":"An overview of the basic science of concussion and subconcussion: where we are and where we are going","volume":"33","author":"Dashnaw","year":"2012","journal-title":"Neurosurg. Focus"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0200","doi-asserted-by":"crossref","first-page":"e9278","DOI":"10.15252\/emmm.201809278","article-title":"D-Aspartate treatment attenuates myelin damage and stimulates myelin repair","volume":"11","author":"de Rosa","year":"2019","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0205","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1002\/mrm.1910340511","article-title":"Reversible decreases in N-acetylaspartate after acute brain injury","volume":"34","author":"De Stefano","year":"1995","journal-title":"Magn. Reson. Med."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0210","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s40478-020-00924-7","article-title":"Biological links between traumatic brain injury and Parkinson's disease","volume":"8","author":"Delic","year":"2020","journal-title":"Acta Neuropathol. Commun."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0215","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/00006123-200008000-00024","article-title":"Do\u011fan attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site N-methyl-D-aspartate receptor antagonist, after experimental traumatic brain injury in rats","volume":"47","author":"Dempsey","year":"2000","journal-title":"Neurosurgery"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0220","first-page":"554","article-title":"Ambient temperature and development of traumatic brain oedema in anaesthetized animals","volume":"77","author":"Dey","year":"1983","journal-title":"Indian J. Med. Res."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0225","first-page":"177","article-title":"Influence of ambient temperature and drug treatments on brain oedema induced by impact injury on skull in rats","volume":"28","author":"Dey","year":"1984","journal-title":"Indian J. Physiol. Pharmacol."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0230","first-page":"25","article-title":"Effect of indomethacin (a prostaglandin synthetase inhibitor) on the permeability of blood-brain and blood-CSF barriers in rat","volume":"24","author":"Dey","year":"1980","journal-title":"Indian J. Physiol. Pharmacol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0235","doi-asserted-by":"crossref","first-page":"147","DOI":"10.2119\/molmed.2013.00153","article-title":"The molecular mechanisms affecting N-acetylaspartate homeostasis following experimental graded traumatic brain injury","volume":"20","author":"Di Pietro","year":"2014","journal-title":"Mol. Med."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0240","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.pmr.2016.12.001","article-title":"Pathophysiology of traumatic brain injury","volume":"28","author":"Dixon","year":"2017","journal-title":"Phys. Med. Rehabil. Clin. N. Am."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0245","doi-asserted-by":"crossref","first-page":"101793","DOI":"10.1016\/j.nicl.2019.101793","article-title":"Cortical thinning in military blast compared to non-blast persistent mild traumatic brain injuries","volume":"22","author":"Eierud","year":"2019","journal-title":"Neuroimage Clin."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0250","doi-asserted-by":"crossref","first-page":"134294","DOI":"10.1016\/j.neulet.2019.134294","article-title":"Relationship of traumatic brain injury to chronic mental health problems and dementia in military veterans","volume":"707","author":"Elder","year":"2019","journal-title":"Neurosci. Lett."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0255","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1152\/ajplegacy.1949.157.1.122","article-title":"Measurement of experimentally induced brain swelling and shrinkage","volume":"157","author":"Elliott","year":"1949","journal-title":"Am. J. Physiol."},{"issue":"5\u20136","key":"10.1016\/bs.pbr.2021.06.016_bb0260","first-page":"429","article-title":"D-aspartate: an atypical amino acid with neuromodulatory activity in mammals","volume":"20","author":"Errico","year":"2009","journal-title":"Rev. Neurosci."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0265","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1002\/glia.22799","article-title":"Neuronal activity and AMPA-type glutamate receptor activation regulates the morphological development of oligodendrocyte precursor cells","volume":"63","author":"Fannon","year":"2015","journal-title":"Glia"},{"issue":"10","key":"10.1016\/bs.pbr.2021.06.016_bb0270","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1111\/sms.13750","article-title":"Recommendations for initial examination, differential diagnosis, and management of concussion and other head injuries in high-level football","volume":"30","author":"Feddermann-Demont","year":"2020","journal-title":"Scand. J. Med. Sci. Sports"},{"issue":"7","key":"10.1016\/bs.pbr.2021.06.016_bb0275","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1177\/0963689717714092","article-title":"Repeated mild traumatic brain injury: potential mechanisms of damage","volume":"26","author":"Fehily","year":"2017","journal-title":"Cell Transplant."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0280","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/0006-291X(86)90047-1","article-title":"D-aspartic acid in purified myelin and myelin basic protein","volume":"135","author":"Fisher","year":"1986","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.1984.tb09689.x","article-title":"Glutamate: a neurotransmitter in mammalian brain","volume":"42","author":"Fonnum","year":"1984","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0290","first-page":"35A","article-title":"GABA synthesis in rat hippocampus correlated to the distribution of inhibitory neurons","volume":"76","author":"Fonnum","year":"1969","journal-title":"Acta Physiol. Scand."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0295","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/0006-8993(73)90724-5","article-title":"The concentration of GABA within inhibitory nerve terminals","volume":"62","author":"Fonnum","year":"1973","journal-title":"Brain Res."},{"issue":"9","key":"10.1016\/bs.pbr.2021.06.016_bb0300","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/BF02532415","article-title":"Amino acid neurotransmission: dynamics of vesicular uptake","volume":"21","author":"Fykse","year":"1996","journal-title":"Neurochem. Res."},{"issue":"Pt. B","key":"10.1016\/bs.pbr.2021.06.016_bb0305","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.mcn.2015.03.001","article-title":"Epidemiology of mild traumatic brain injury and neurodegenerative disease","volume":"66","author":"Gardner","year":"2015","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0310","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/B978-0-12-802973-2.00012-4","article-title":"Neuroepidemiology of traumatic brain injury","volume":"138","author":"Gardner","year":"2016","journal-title":"Handb. Clin. Neurol."},{"issue":"Suppl. 4(0 4)","key":"10.1016\/bs.pbr.2021.06.016_bb0315","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1227\/NEU.0000000000000505","article-title":"The new neurometabolic cascade of concussion","volume":"75","author":"Giza","year":"2014","journal-title":"Neurosurgery"},{"issue":"134","key":"10.1016\/bs.pbr.2021.06.016_bb0320","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3003716","article-title":"Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model","volume":"4","author":"Goldstein","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0325","doi-asserted-by":"crossref","first-page":"4894","DOI":"10.12659\/MSM.898185","article-title":"Potassium aspartate attenuates brain injury induced by controlled cortical impact in rats through increasing adenosine triphosphate (ATP) Levels, Na+\/K+-ATPase activity and reducing brain edema","volume":"22","author":"Gu","year":"2016","journal-title":"Med. Sci. Monit."},{"issue":"5","key":"10.1016\/bs.pbr.2021.06.016_bb0330","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s11910-015-0545-1","article-title":"Glutamate and GABA imbalance following traumatic brain injury","volume":"15","author":"Guerriero","year":"2015","journal-title":"Curr. Neurol. Neurosci. Rep."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0335","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1134\/S0006297917030087","article-title":"Interplay between brain BDNF and glutamatergic systems: a brief state of the evidence and association with the pathogenesis of depression","volume":"82","author":"Gulyaeva","year":"2017","journal-title":"Biochemistry (Mosc.)"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0340","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/00004647-200101000-00006","article-title":"Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study","volume":"21","author":"Gundersen","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb0345","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1080\/14737175.2016.1205487","article-title":"Treatment of persistent post-concussion syndrome due to mild traumatic brain injury: current status and future directions","volume":"16","author":"Hadanny","year":"2016","journal-title":"Expert Rev. Neurother."},{"issue":"5","key":"10.1016\/bs.pbr.2021.06.016_bb0350","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.3390\/ijms21051786","article-title":"Using serum amino acids to predict traumatic brain injury: a systematic approach to utilize multiple biomarkers","volume":"21","author":"Hajiaghamemar","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0355","doi-asserted-by":"crossref","first-page":"464","DOI":"10.3390\/biom10030464","article-title":"Ionotropic glutamate receptors in epilepsy: a review focusing on AMPA and NMDA receptors","volume":"10","author":"Hanada","year":"2020","journal-title":"Biomolecules"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0360","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1136\/bjsports-2012-091941","article-title":"American Medical Society for Sports Medicine position statement: concussion in sport","volume":"47","author":"Harmon","year":"2013","journal-title":"Br. J. Sports Med."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0365","first-page":"102","article-title":"Blast-associated traumatic brain injury in the military as a potential trigger for dementia and chronic traumatic encephalopathy","volume":"1\u201317","author":"Hasoon","year":"2017","journal-title":"U.S. Army Med. Dep. J."},{"issue":"Suppl. 1","key":"10.1016\/bs.pbr.2021.06.016_bb0370","first-page":"S173","article-title":"Neurotransmitter-mediated mechanisms of traumatic brain injury: acetylcholine and excitatory amino acids","volume":"9","author":"Hayes","year":"1992","journal-title":"J. Neurotrauma"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0375","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neubiorev.2016.01.007","article-title":"Role of GABA(B) receptors in learning and memory and neurological disorders","volume":"63","author":"Heaney","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0380","doi-asserted-by":"crossref","first-page":"132","DOI":"10.7205\/MILMED-D-09-00238","article-title":"Inpatient hospitalizations of U.S. military personnel medically evacuated from Iraq and Afghanistan with combat-related traumatic brain injury","volume":"176","author":"Heltemes","year":"2011","journal-title":"Mil. Med."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0385","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/nn.4209","article-title":"Hypothalamic feedforward inhibition of thalamocortical network controls arousal and consciousness","volume":"19","author":"Herrera","year":"2016","journal-title":"Nat. Neurosci."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0390","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0149-7634(96)00033-4","article-title":"On the release of glutamate and aspartate in the basal ganglia of the rat: interactions with monoamines and neuropeptides","volume":"21","author":"Herrera-Marschitz","year":"1997","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1\u20133","key":"10.1016\/bs.pbr.2021.06.016_bb0395","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/BF01345262","article-title":"Release of endogenous excitatory amino acids in the neostriatum of the rat under physiological and pharmacologically-induced conditions","volume":"14","author":"Herrera-Marschitz","year":"1998","journal-title":"Amino Acids"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0400","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.spen.2019.03.017","article-title":"Concussion: a global perspective","volume":"30","author":"Hon","year":"2019","journal-title":"Semin. Pediatr. Neurol."},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb0405","doi-asserted-by":"crossref","first-page":"140428","DOI":"10.1016\/j.bbapap.2020.140428","article-title":"Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders","volume":"1868","author":"Hook","year":"2020","journal-title":"Biochim. Biophys. Acta Proteins Proteomics"},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0410","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s10827-018-0677-9","article-title":"Perceptual judgments via sensory-motor interaction assisted by cortical GABA","volume":"44","author":"Hoshino","year":"2018","journal-title":"J. Comput. Neurosci."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0415","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.expneurol.2017.05.002","article-title":"Effects of experimental traumatic brain injury and impaired glutamate transport on cortical spreading depression","volume":"295","author":"Hosseini-Zare","year":"2017","journal-title":"Exp. Neurol."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0420","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1177\/0009922818806308","article-title":"Quality of life and symptom burden 1 month after concussion in children and adolescents","volume":"58","author":"Howell","year":"2019","journal-title":"Clin. Pediatr. (Phila)"},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0425","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00701-019-03807-6","article-title":"Management of concussion in soccer","volume":"161","author":"Hubertus","year":"2019","journal-title":"Acta Neurochir."},{"issue":"2\u20134","key":"10.1016\/bs.pbr.2021.06.016_bb0430","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/BF01407455","article-title":"Brain swelling and brain oedema in acute head injury","volume":"79","author":"Ito","year":"1986","journal-title":"Acta Neurochir."},{"issue":"12","key":"10.1016\/bs.pbr.2021.06.016_bb0435","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1136\/bjsports-2017-097729","article-title":"Predictors of clinical recovery from concussion: a systematic review","volume":"51","author":"Iverson","year":"2017","journal-title":"Br. J. Sports Med."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0440","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.mcna.2018.10.005","article-title":"Concussion evaluation and management","volume":"103","author":"Jackson","year":"2019","journal-title":"Med. Clin. North Am."},{"issue":"10","key":"10.1016\/bs.pbr.2021.06.016_bb0445","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1016\/j.injury.2014.08.044","article-title":"Mild traumatic brain injury and motor vehicle crashes: limitations to our understanding","volume":"46","author":"Jagnoor","year":"2015","journal-title":"Injury"},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0450","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1136\/jnnp-2019-321759","article-title":"Distinct dopaminergic abnormalities in traumatic brain injury and Parkinson's disease","volume":"91","author":"Jenkins","year":"2020","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"Pt. B","key":"10.1016\/bs.pbr.2021.06.016_bb0455","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.neuropharm.2018.08.004","article-title":"Pathophysiology and treatment of cerebral edema in traumatic brain injury","volume":"145","author":"Jha","year":"2019","journal-title":"Neuropharmacology"},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0460","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.pmr.2011.08.001","article-title":"Epidemiology of youth sports concussion","volume":"22","author":"Jinguji","year":"2011","journal-title":"Phys. Med. Rehabil. Clin. N. Am."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0465","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00702-010-0498-0","article-title":"Traumatic brain injury and recovery mechanisms: peptide modulation of periventricular neurogenic regions by the choroid plexus-CSF nexus","volume":"118","author":"Johanson","year":"2011","journal-title":"J. Neural Transm. (Vienna)"},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0470","doi-asserted-by":"crossref","first-page":"R704","DOI":"10.1152\/ajpregu.00114.2014","article-title":"Caffeine promotes glutamate and histamine release in the posterior hypothalamus","volume":"307","author":"John","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"7","key":"10.1016\/bs.pbr.2021.06.016_bb0475","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1080\/02699052.2019.1606445","article-title":"Longitudinal patterns of behavior, cognition, and quality of life after mild traumatic brain injury in children: BIONIC study findings","volume":"33","author":"Jones","year":"2019","journal-title":"Brain Inj."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0480","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.bbr.2007.09.035","article-title":"The differential effects of cervical and thoracic dorsal funiculus lesions in rats","volume":"187","author":"Kanagal","year":"2008","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/bs.pbr.2021.06.016_bb0485","doi-asserted-by":"crossref","first-page":"E5","DOI":"10.3171\/foc.2007.22.5.6","article-title":"Tissue hyperosmolality and brain edema in cerebral contusion","volume":"22","author":"Kawamata","year":"2007","journal-title":"Neurosurg. Focus"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0490","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.spen.2019.03.003","article-title":"Definition, classification, and epidemiology of concussion","volume":"30","author":"Kazl","year":"2019","journal-title":"Semin. Pediatr. Neurol."},{"issue":"7","key":"10.1016\/bs.pbr.2021.06.016_bb0495","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1007\/s10072-017-2938-1","article-title":"Pathogenic mechanisms following ischemic stroke","volume":"38","author":"Khoshnam","year":"2017","journal-title":"Neurol. Sci."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0500","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1212\/WNL.0000000000000105","article-title":"Myoinositol and glutamate complex neurometabolite abnormality after mild traumatic brain injury","volume":"82","author":"Kierans","year":"2014","journal-title":"Neurology"},{"issue":"12","key":"10.1016\/bs.pbr.2021.06.016_bb0505","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.3390\/ijms20122943","article-title":"Interactions of glutamatergic neurotransmission and Brain-derived neurotrophic factor in the regulation of behaviors after nicotine administration","volume":"20","author":"Kim","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0510","doi-asserted-by":"crossref","first-page":"672","DOI":"10.3389\/fimmu.2018.00672","article-title":"The inflammatory continuum of traumatic brain injury and Alzheimer's disease","volume":"9","author":"Kokiko-Cochran","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0515","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.neuropharm.2015.12.013","article-title":"Persistent elevation of D-Aspartate enhances NMDA receptor-mediated responses in mouse substantia nigra pars compacta dopamine neurons","volume":"103","author":"Krashia","year":"2016","journal-title":"Neuropharmacology"},{"issue":"10","key":"10.1016\/bs.pbr.2021.06.016_bb0520","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0186243","article-title":"Ceftriaxone- and N-acetylcysteine-induced brain tolerance to ischemia: influence on glutamate levels in focal cerebral ischemia","volume":"12","author":"Krzy\u017canowska","year":"2017","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb1268","doi-asserted-by":"crossref","first-page":"E60","DOI":"10.1097\/HTR.0000000000000503","article-title":"Increasing incidence of concussion: true epidemic or better recognition?","volume":"35","author":"Langer","year":"2020","journal-title":"J. Head Trauma Rehabil."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0525","doi-asserted-by":"crossref","first-page":"E4","DOI":"10.3171\/2018.9.FOCUS18359","article-title":"Two-year mortality and functional outcomes in combat-related penetrating brain injury: battlefield through rehabilitation","volume":"45","author":"Larkin","year":"2018","journal-title":"Neurosurg. Focus"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0530","first-page":"64","article-title":"The interaction between neuropeptides and excitatory amino acids in seizure phenomena","volume":"49","author":"Laso\u0144","year":"1997","journal-title":"Pol. J. Pharmacol."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0535","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s00424-010-0809-1","article-title":"Glutamate receptors, neurotoxicity and neurodegeneration","volume":"460","author":"Lau","year":"2010","journal-title":"Pflugers Arch."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0540","doi-asserted-by":"crossref","first-page":"299","DOI":"10.4085\/1062-6050-51.11.08","article-title":"A physiological approach to prolonged recovery from sport-related concussion","volume":"52","author":"Leddy","year":"2017","journal-title":"J. Athl. Train."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb1266","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1006\/excr.1997.4026","article-title":"Apoptosis, excitotoxicity, and neuropathology","volume":"239","author":"Leist","year":"1998","journal-title":"Exp. Cell Res."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0545","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1590\/S0100-879X2009000100011","article-title":"Unconventional neurotransmitters, neurodegeneration and neuroprotection","volume":"42","author":"Leonelli","year":"2009","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"9","key":"10.1016\/bs.pbr.2021.06.016_bb0550","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.2967\/jnumed.115.167403","article-title":"Ex vivo tracing of NMDA and GABA-A receptors in rat brain after traumatic brain injury using 18F-GE-179 and 18F-GE-194 autoradiography","volume":"57","author":"L\u00f3pez-Pic\u00f3n","year":"2016","journal-title":"J. Nucl. Med."},{"issue":"6173","key":"10.1016\/bs.pbr.2021.06.016_bb0555","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1126\/science.1247485","article-title":"Dendritic inhibition in the hippocampus supports fear learning","volume":"343","author":"Lovett-Barron","year":"2014","journal-title":"Science"},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0560","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3233\/NRE-192702","article-title":"Sleep problems contribute to post-concussive symptoms in service members with a history of mild traumatic brain injury without posttraumatic stress disorder or major depressive disorder","volume":"44","author":"Lu","year":"2019","journal-title":"NeuroRehabilitation"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0565","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/cne.20080","article-title":"Immunohistochemical localization of aspartoacylase in the rat central nervous system","volume":"472","author":"Madhavarao","year":"2004","journal-title":"J. Comp. Neurol."},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb0570","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1523\/JNEUROSCI.19-08-03057.1999","article-title":"Differential c-Fos expression in cholinergic, monoaminergic, and GABAergic cell groups of the pontomesencephalic tegmentum after paradoxical sleep deprivation and recovery","volume":"19","author":"Maloney","year":"1999","journal-title":"J. Neurosci."},{"issue":"12","key":"10.1016\/bs.pbr.2021.06.016_bb0575","doi-asserted-by":"crossref","first-page":"4669","DOI":"10.1523\/JNEUROSCI.20-12-04669.2000","article-title":"c-Fos expression in GABAergic, serotonergic, and other neurons of the pontomedullary reticular formation and raphe after paradoxical sleep deprivation and recovery","volume":"20","author":"Maloney","year":"2000","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0580","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1258\/002367795780740023","article-title":"An investigation into the effects of solid or grid cage flooring on the welfare of laboratory rats","volume":"29","author":"Manser","year":"1995","journal-title":"Lab Anim."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0585","doi-asserted-by":"crossref","first-page":"688","DOI":"10.3109\/02699052.2015.1004755","article-title":"mTBI Expert Consensus Group.Updated clinical practice guidelines for concussion\/mild traumatic brain injury and persistent symptoms","volume":"29","author":"Marshall","year":"2015","journal-title":"Brain Inj."},{"issue":"13\u201314","key":"10.1016\/bs.pbr.2021.06.016_bb0590","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1080\/02699052.2016.1192683","article-title":"Traumatic brain injury: the first 15 milliseconds","volume":"30","author":"Martin","year":"2016","journal-title":"Brain Inj."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0595","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0361-9230(98)00024-0","article-title":"Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis","volume":"46","author":"Martin","year":"1998","journal-title":"Brain Res. Bull."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0600","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/nmeth.2333","article-title":"An optimized fluorescent probe for visualizing glutamate neurotransmission","volume":"10","author":"Marvin","year":"2013","journal-title":"Nat. Methods"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0605","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/978-1-4684-5769-8_24","article-title":"Excitatory amino acids, growth factors, and calcium: a teeter-totter model for neural plasticity and degeneration","volume":"268","author":"Mattson","year":"1990","journal-title":"Adv. Exp. Med. Biol."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0610","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/j.1469-7580.2010.01339.x","article-title":"Glutamate and ATP signalling in white matter pathology","volume":"219","author":"Matute","year":"2011","journal-title":"J. Anat."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0615","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1097\/00005373-198606000-00008","article-title":"Moped and motorcycle accidents\u2014similarities and discrepancies","volume":"26","author":"M\u00e4tzsch","year":"1986","journal-title":"J. Trauma"},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0620","doi-asserted-by":"crossref","first-page":"309","DOI":"10.4085\/1062-6050-52.1.14","article-title":"Long-term cognitive and neuropsychiatric consequences of repetitive concussion and head-impact exposure","volume":"52","author":"McAllister","year":"2017","journal-title":"J. Athl. Train."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0625","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0174847","article-title":"Mild traumatic brain injury (mTBI) and chronic cognitive impairment: a scoping review","volume":"12","author":"McInnes","year":"2017","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0630","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3233\/NRE-192804","article-title":"Traumatic brain injury and sleep disturbances in combat-exposed service members and veterans: where to go next?","volume":"45","author":"McKeon","year":"2019","journal-title":"NeuroRehabilitation"},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0635","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/BF00814005","article-title":"Simultaneous determination of cholecystokinin, dopamine, glutamate and aspartate in cortex and striatum of the rat using in vivo microdialysis","volume":"1","author":"Meana","year":"1991","journal-title":"Amino Acids"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0640","doi-asserted-by":"crossref","first-page":"40","DOI":"10.2174\/187152712799960781","article-title":"Cerebrolysin, a mixture of neurotrophic factors induces marked neuroprotection in spinal cord injury following intoxication of engineered nanoparticles from metals","volume":"11","author":"Menon","year":"2012","journal-title":"CNS Neurol. Disord. Drug Targets"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0645","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s12883-020-1622-x","article-title":"Improving symptom burden in adults with persistent post-concussive symptoms: a randomized aerobic exercise trial protocol","volume":"20","author":"Mercier","year":"2020","journal-title":"BMC Neurol."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0650","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1001\/jama.2017.8334","article-title":"Clinicopathological evaluation of chronic traumatic encephalopathy in players of American football","volume":"318","author":"Mez","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0655","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.pneurobio.2006.12.003","article-title":"N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology","volume":"81","author":"Moffett","year":"2007","journal-title":"Prog. Neurobiol."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0660","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0022-510X(89)90048-8","article-title":"Role of histamine in traumatic brain edema. An experimental study in the rat","volume":"90","author":"Mohanty","year":"1989","journal-title":"J. Neurol. Sci."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0665","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1089\/neu.2016.4413","article-title":"Cumulative head impact exposure predicts later-life depression, apathy, executive dysfunction, and cognitive impairment in former high school and college football players","volume":"34","author":"Montenigro","year":"2017","journal-title":"J. Neurotrauma"},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0670","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.neulet.2012.08.042","article-title":"Valproate causes reduction of the excitatory amino acid aspartate in nerve terminals","volume":"527","author":"Morland","year":"2012","journal-title":"Neurosci. Lett."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0675","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1097\/HTR.0000000000000213","article-title":"Neuroimaging in blast-related mild traumatic brain injury","volume":"32","author":"Mu","year":"2017","journal-title":"J. Head Trauma Rehabil."},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb0680","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.amjmed.2017.04.016","article-title":"Concussion","volume":"130","author":"Mullally","year":"2017","journal-title":"Am. J. Med."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0685","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/0896-6273(95)90222-8","article-title":"The cellular Na+ pump as a site of action for carbon monoxide and glutamate: a mechanism for long-term modulation of cellular activity","volume":"14","author":"Nathanson","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/bs.pbr.2021.06.016_bb1267","first-page":"95","article-title":"Neuronal necrosis and apoptosis: two distinct events induced by exposure to glutamate or oxidative stress","volume":"72","author":"Nicotera","year":"1997","journal-title":"Adv. Neurol."},{"issue":"10","key":"10.1016\/bs.pbr.2021.06.016_bb0690","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1089\/neu.1997.14.677","article-title":"Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury?","volume":"14","author":"Obrenovitch","year":"1997","journal-title":"J. Neurotrauma"},{"issue":"9","key":"10.1016\/bs.pbr.2021.06.016_bb0695","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1007\/s11064-009-9961-4","article-title":"Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia","volume":"34","author":"Oja","year":"2009","journal-title":"Neurochem. Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0700","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0079-6123(08)62335-3","article-title":"Release of endogenous neurochemicals may increase vascular permeability, induce edema and influence cell changes in trauma to the spinal cord","volume":"91","author":"Olsson","year":"1992","journal-title":"Prog. Brain Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0705","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0079-6123(08)61802-6","article-title":"The opioid receptor antagonist naloxone influences the pathophysiology of spinal cord injury","volume":"104","author":"Olsson","year":"1995","journal-title":"Prog. Brain Res."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0710","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1089\/neu.1995.12.527","article-title":"Head injury mechanisms and the concept of preventive management: a review and critical synthesis","volume":"12","author":"Ommaya","year":"1995","journal-title":"J. Neurotrauma"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0715","doi-asserted-by":"crossref","first-page":"112261","DOI":"10.1016\/j.bbr.2019.112261","article-title":"Contribution of GABA(A) receptor subunits to attention and social behavior","volume":"378","author":"Paine","year":"2020","journal-title":"Behav. Brain Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0720","first-page":"535","article-title":"Blockade of histamine H2 receptors attenuate blood-brain barrier permeability, cerebral blood flow disturbances, edema formation and cell reactions following hyperthermic brain injury in the rat","volume":"76","author":"Patnaik","year":"2000","journal-title":"Acta Neurochir. Suppl."},{"issue":"21","key":"10.1016\/bs.pbr.2021.06.016_bb0725","doi-asserted-by":"crossref","first-page":"7290","DOI":"10.1523\/JNEUROSCI.5118-09.2010","article-title":"Zones of enhanced glutamate release from climbing fibers in the mammalian cerebellum","volume":"30","author":"Paukert","year":"2010","journal-title":"J. Neurosci."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0730","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3171\/2015.2.JNS14503","article-title":"Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis","volume":"124","author":"Perry","year":"2016","journal-title":"J. Neurosurg."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0735","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.nic.2017.09.010","article-title":"Definition of traumatic brain injury, neurosurgery, trauma orthopedics, neuroimaging, psychology, and psychiatry in mild traumatic brain injury","volume":"28","author":"Pervez","year":"2018","journal-title":"Neuroimaging Clin. N. Am."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0740","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1177\/1073858402238515","article-title":"GABA and glutamate in the human brain","volume":"8","author":"Petroff","year":"2002","journal-title":"Neuroscientist"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0745","first-page":"13","article-title":"Results of brain injury primary surgical treatment in a complex care for patients with combat-related penetrating craniocerebral gunshot wound at a specialized medical facility","volume":"301","author":"Pilipenko","year":"2020","journal-title":"Georgian Med. News"},{"issue":"1\u20132","key":"10.1016\/bs.pbr.2021.06.016_bb0750","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0006-8993(93)90636-2","article-title":"Effects of serotonergic drugs in experimental brain ischemia: evidence for a protective role of serotonin in cerebral ischemia","volume":"630","author":"Prehn","year":"1993","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0755","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3928\/01477447-20181231-02","article-title":"Concussions in sports","volume":"42","author":"Provencher","year":"2019","journal-title":"Orthopedics"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0760","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ebiom.2018.01.021","article-title":"Traumatic brain injury and Alzheimer's disease: the cerebrovascular link","volume":"28","author":"Ramos-Cejudo","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0765","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0079-6123(08)61793-8","article-title":"Interaction of neuropeptides and excitatory amino acids in the rat superficial spinal dorsal horn","volume":"104","author":"Randi\u0107","year":"1995","journal-title":"Prog. Brain Res."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0770","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/cns.12828","article-title":"Corticostriatal network dysfunction in Huntington's disease: deficits in neural processing, glutamate transport, and ascorbate release","volume":"24","author":"Rebec","year":"2018","journal-title":"CNS Neurosci. Ther."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0775","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/HTR.0000000000000417","article-title":"Traumatic brain injury following military deployment: evaluation of diagnosis and cause of injury","volume":"34","author":"Regasa","year":"2019","journal-title":"J. Head Trauma Rehabil."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0780","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1007\/s12035-015-9235-x","article-title":"PLGA nanoparticles loaded cerebrolysin: studies on their preparation and investigation of the effect of storage and serum stability with reference to traumatic brain injury","volume":"52","author":"Ruozi","year":"2015","journal-title":"Mol. Neurobiol."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0785","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1080\/09540260310001606692","article-title":"Post concussion syndrome","volume":"15","author":"Ryan","year":"2003","journal-title":"Int. Rev. Psychiatry"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0790","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1046\/j.1471-4159.1997.68020675.x","article-title":"Transient elevation of interstitial N-acetylaspartate in reversible global brain ischemia","volume":"68","author":"Sager","year":"1997","journal-title":"J. Neurochem."},{"issue":"7","key":"10.1016\/bs.pbr.2021.06.016_bb0795","first-page":"426","article-title":"Current concepts in concussion: initial evaluation and management","volume":"99","author":"Scorza","year":"2019","journal-title":"Am. Fam. Physician"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0800","doi-asserted-by":"crossref","first-page":"e180210","DOI":"10.1001\/jamanetworkopen.2018.0210","article-title":"Assessment of follow-up care after emergency department presentation for mild traumatic brain injury and concussion: results from the TRACK-TBI study","volume":"1","author":"Seabury","year":"2018","journal-title":"JAMA Netw. Open"},{"issue":"7","key":"10.1016\/bs.pbr.2021.06.016_bb0805","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1037\/neu0000299","article-title":"The contribution of posttraumatic stress disorder and mild traumatic brain injury to persistent post concussive symptoms following motor vehicle accidents","volume":"30","author":"Segev","year":"2016","journal-title":"Neuropsychology"},{"issue":"7","key":"10.1016\/bs.pbr.2021.06.016_bb0810","doi-asserted-by":"crossref","first-page":"3068","DOI":"10.1021\/acschemneuro.9b00044","article-title":"Serotonin and glutamate interactions in preclinical schizophrenia models","volume":"10","author":"Shah","year":"2019","journal-title":"ACS Chem. Nerosci."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0815","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1089\/neu.2015.3950","article-title":"Carpenter KL extracellular N-Acetylaspartate in human traumatic brain injury","volume":"33","author":"Shannon","year":"2016","journal-title":"J. Neurotrauma"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0820","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0028-3908(87)90049-9","article-title":"Effect of captopril (a converting enzyme inhibitor) on blood-brain barrier permeability and cerebral blood flow in normotensive rats","volume":"26","author":"Sharma","year":"1987","journal-title":"Neuropharmacology"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0825","first-page":"159","article-title":"A bradykinin BK2 receptor antagonist HOE-140 attenuates blood-spinal cord barrier permeability following a focal trauma to the rat spinal cord. An experimental study using Evans blue, [131]I-sodium and lanthanum tracers","volume":"76","author":"Sharma","year":"2000","journal-title":"Acta Neurochir. Suppl."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0830","series-title":"The Blood-Spinal Cord and Brain Barriers in Health and Disease","first-page":"159","article-title":"Histamine influences the blood-spinal cord and brain barriers following injuries to the central nervous system","author":"Sharma","year":"2004"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0835","series-title":"The Blood-Spinal Cord and Brain Barriers in Health and Disease","first-page":"117","article-title":"Influence of serotonin on the blood-brain and blood-spinal cord barriers","author":"Sharma","year":"2004"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0840","series-title":"The Blood-Spinal Cord and Brain Barriers in Health and Disease","first-page":"437","article-title":"Pathophysiology of the blood-spinal cord barrier in traumatic injury","author":"Sharma","year":"2004"},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0845","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s00702-005-0406-1","article-title":"Hyperthermia influences excitatory and inhibitory amino acid neurotransmitters in the central nervous system. An experimental study in the rat using behavioural, biochemical, pharmacological, and morphological approaches","volume":"113","author":"Sharma","year":"2006","journal-title":"J. Neural Transm. (Vienna)"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0850","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0079-6123(06)62015-3","article-title":"Interaction between amino acid neurotransmitters and opioid receptors in hyperthermia-induced brain pathology","volume":"162","author":"Sharma","year":"2007","journal-title":"Prog. Brain Res."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0855","doi-asserted-by":"crossref","first-page":"753","DOI":"10.2217\/17435889.2.6.753","article-title":"Nanoneuroscience: emerging concepts on nanoneurotoxicity and nanoneuroprotection","volume":"2","author":"Sharma","year":"2007","journal-title":"Nanomedicine (Lond.)"},{"issue":"18","key":"10.1016\/bs.pbr.2021.06.016_bb0860","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.2174\/138161207780858410","article-title":"Neurotrophic factors in combination: a possible new therapeutic strategy to influence pathophysiology of spinal cord injury and repair mechanisms","volume":"13","author":"Sharma","year":"2007","journal-title":"Curr. Pharm. Des."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0865","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s00702-010-0514-4","article-title":"Early microvascular reactions and blood-spinal cord barrier disruption are instrumental in pathophysiology of spinal cord injury and repair: novel therapeutic strategies including nanowired drug delivery to enhance neuroprotection","volume":"118","author":"Sharma","year":"2011","journal-title":"J. Neural Transm. (Vienna)"},{"issue":"1\u20133","key":"10.1016\/bs.pbr.2021.06.016_bb0870","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00726-001-0136-0","article-title":"Nitric oxide synthase inhibitors influence dynorphin A (1-17) immunoreactivity in the rat brain following hyperthermia","volume":"23","author":"Sharma","year":"2002","journal-title":"Amino Acids"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0875","first-page":"383","article-title":"Brain oedema and cellular changes induced by acute heat stress in young rats","volume":"51","author":"Sharma","year":"1990","journal-title":"Acta Neurochir. Suppl. (Wien)"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0880","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0022-510X(86)90036-5","article-title":"Influence of long-term immobilization stress on regional blood-brain barrier permeability, cerebral blood flow and 5-HT level in conscious normotensive young rats","volume":"72","author":"Sharma","year":"1986","journal-title":"J. Neurol. Sci."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0885","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0028-3908(86)90037-7","article-title":"Probable involvement of 5-hydroxytryptamine in increased permeability of blood-brain barrier under heat stress in young rats","volume":"25","author":"Sharma","year":"1986","journal-title":"Neuropharmacology"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0890","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0006-8993(87)91205-4","article-title":"Influence of long-term acute heat exposure on regional blood-brain barrier permeability, cerebral blood flow and 5-HT level in conscious normotensive young rats","volume":"424","author":"Sharma","year":"1987","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb0895","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/BF00294237","article-title":"Edema formation and cellular alterations following spinal cord injury in the rat and their modification with p-chlorophenylalanine","volume":"79","author":"Sharma","year":"1990","journal-title":"Acta Neuropathol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0900","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/B978-0-12-386986-9.00002-8","article-title":"Monoclonal antibodies as novel neurotherapeutic agents in CNS injury and repair","volume":"102","author":"Sharma","year":"2012","journal-title":"Int. Rev. Neurobiol."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0905","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/wnan.172","article-title":"Nanowired drug delivery for neuroprotection in central nervous system injuries: modulation by environmental temperature, intoxication of nanoparticles, and comorbidity factors","volume":"4","author":"Sharma","year":"2012","journal-title":"Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol."},{"issue":"5","key":"10.1016\/bs.pbr.2021.06.016_bb0910","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1007\/s00726-013-1584-z","article-title":"New perspectives of nanoneuroprotection, nanoneuropharmacology and nanoneurotoxicity: modulatory role of amino acid neurotransmitters, stress, trauma, and co-morbidity factors in nanomedicine","volume":"45","author":"Sharma","year":"2013","journal-title":"Amino Acids"},{"issue":"1\u20133","key":"10.1016\/bs.pbr.2021.06.016_bb0915","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s00726-001-0137-z","article-title":"A new antioxidant compound H-290\/51 modulates glutamate and GABA immunoreactivity in the rat spinal cord following trauma","volume":"23","author":"Sharma","year":"2002","journal-title":"Amino Acids"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0920","first-page":"134","article-title":"Prostaglandins modulate constitutive isoform of heat shock protein (72 kD) response following trauma to the rat spinal cord","volume":"70","author":"Sharma","year":"1997","journal-title":"Acta Neurochir. Suppl."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb0925","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/BF00294216","article-title":"Increased 5-hydroxytryptamine immunoreactivity in traumatized spinal cord. An experimental study in the rat","volume":"80","author":"Sharma","year":"1990","journal-title":"Acta Neuropathol."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0930","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/0306-4522(90)90014-U","article-title":"Early accumulation of serotonin in rat spinal cord subjected to traumatic injury. Relation to edema and blood flow changes","volume":"36","author":"Sharma","year":"1990","journal-title":"Neuroscience"},{"key":"10.1016\/bs.pbr.2021.06.016_bb0935","first-page":"104","article-title":"Rearing at high ambient temperature during later phase of the brain development enhances functional plasticity of the CNS and induces tolerance to heat stress. An experimental study in the conscious normotensive young rats","volume":"4","author":"Sharma","year":"1991","journal-title":"Brain Dysfunction"},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0940","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/00001756-199103000-00012","article-title":"Acute heat exposure causes cellular alteration in cerebral cortex of young rats","volume":"2","author":"Sharma","year":"1991","journal-title":"Neuroreport"},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0945","first-page":"133","article-title":"Role of serotonin in heat adaptation: an experimental study in the conscious young rat","volume":"26","author":"Sharma","year":"1992","journal-title":"Endocr. Regul."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0950","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/0306-4522(92)90277-9","article-title":"Acute systemic heat stress increases glial fibrillary acidic protein immunoreactivity in brain: experimental observations in conscious normotensive young rats","volume":"48","author":"Sharma","year":"1992","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0955","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0306-4522(93)90076-R","article-title":"Prostaglandins modulate alterations of microvascular permeability, blood flow, edema and serotonin levels following spinal cord injury: an experimental study in the rat","volume":"57","author":"Sharma","year":"1993","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb0960","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/BF00227761","article-title":"Early perifocal cell changes and edema in traumatic injury of the spinal cord are reduced by indomethacin, an inhibitor of prostaglandin synthesis. Experimental study in the rat","volume":"85","author":"Sharma","year":"1993","journal-title":"Acta Neuropathol."},{"issue":"5","key":"10.1016\/bs.pbr.2021.06.016_bb0965","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/BF00228575","article-title":"p-Chlorophenylalanine, a serotonin synthesis inhibitor, reduces the response of glial fibrillary acidic protein induced by trauma to the spinal cord. An immunohistochemical investigation in the rat","volume":"86","author":"Sharma","year":"1993","journal-title":"Acta Neuropathol."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb0970","first-page":"207","article-title":"Trauma-induced opening of the the blood-spinal cord barrier is reduced by indomethacin, an inhibitor of prostaglandin biosynthesis. Experimental observations in the rat using [131I]-sodium, Evans blue and lanthanum as tracers","volume":"7","author":"Sharma","year":"1995","journal-title":"Restor. Neurol. Neurosci."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb0975","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0168-0102(94)00855-A","article-title":"A serotonin synthesis inhibitor, p-chlorophenylalanine reduces the heat shock protein response following trauma to the spinal cord: an immunohistochemical and ultrastructural study in the rat","volume":"21","author":"Sharma","year":"1995","journal-title":"Neurosci. Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0980","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/j.1749-6632.1997.tb51747.x","article-title":"Opioid receptor antagonists attenuate heat stress-induced reduction in cerebral blood flow, increased blood-brain barrier permeability, vasogenic edema and cell changes in the rat","volume":"813","author":"Sharma","year":"1997","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0985","first-page":"155","article-title":"Topical application of 5-HT antibodies reduces edema and cell changes following trauma of the rat spinal cord","volume":"70","author":"Sharma","year":"1997","journal-title":"Acta Neurochir. Suppl."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0990","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0079-6123(08)62043-9","article-title":"Pathophysiology of brain edema and cell changes following hyperthermic brain injury","volume":"115","author":"Sharma","year":"1998","journal-title":"Prog. Brain Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb0995","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0079-6123(08)62041-5","article-title":"Nitric oxide and carbon monoxide in the brain pathology of heat stress","volume":"115","author":"Sharma","year":"1998","journal-title":"Prog. Brain Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1000","first-page":"91","article-title":"p-Chlorophenylalanine, an inhibitor of serotonin synthesis reduces blood-brain barrier permeability, cerebral blood flow, edema formation and cell injury following trauma to the rat brain","volume":"76","author":"Sharma","year":"2000","journal-title":"Acta Neurochir. Suppl."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1005","first-page":"297","article-title":"Spinal cord injury induced c-fos expression is reduced by p-CPA, a serotonin synthesis inhibitor. An experimental study using immunohistochemistry in the rat","volume":"76","author":"Sharma","year":"2000","journal-title":"Acta Neurochir. Suppl."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1010","first-page":"541","article-title":"Selective alteration of calcitonin gene related peptide in hyperthermic brain injury. An experimental study in the rat brain using immunohistochemistry","volume":"76","author":"Sharma","year":"2000","journal-title":"Acta Neurochir. Suppl."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1015","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1196\/annals.1403.022","article-title":"Antibodies to serotonin attenuate closed head injury induced blood brain barrier disruption and brain pathology","volume":"1122","author":"Sharma","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1020","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/978-3-211-98811-4_56","article-title":"Antibodies to dynorphin a (1-17) attenuate closed head injury induced blood-brain barrier disruption, brain edema formation and brain pathology in the rat","volume":"106","author":"Sharma","year":"2010","journal-title":"Acta Neurochir. Suppl."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb1025","doi-asserted-by":"crossref","first-page":"7","DOI":"10.2174\/187152712799960790","article-title":"Superior neuroprotective effects of cerebrolysin in nanoparticle-induced exacerbation of hyperthermia-induced brain pathology","volume":"11","author":"Sharma","year":"2012","journal-title":"CNS Neurol. Disord. Drug Targets"},{"issue":"9","key":"10.1016\/bs.pbr.2021.06.016_bb1030","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.2174\/1871527315666160902145145","article-title":"Pathophysiology of blood-brain barrier in brain injury in cold and hot environments: novel drug targets for neuroprotection","volume":"15","author":"Sharma","year":"2016","journal-title":"CNS Neurol. Disord. Drug Targets"},{"issue":"9","key":"10.1016\/bs.pbr.2021.06.016_bb1035","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.2174\/1871527315666160819123059","article-title":"Nanowired drug delivery across the blood-brain barrier in central nervous system injury and repair","volume":"15","author":"Sharma","year":"2016","journal-title":"CNS Neurol. Disord. Drug Targets"},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb1040","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2217\/nmt-2016-0037","article-title":"Alzheimer's disease: cerebrolysin and nanotechnology as a therapeutic strategy","volume":"6","author":"Sharma","year":"2016","journal-title":"Neurodegener. Dis. Manag."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1045","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/bs.irn.2017.09.002","article-title":"Novel treatment strategies using TiO(2)-nanowired delivery of histaminergic drugs and antibodies to tau with cerebrolysin for superior neuroprotection in the pathophysiology of Alzheimer's disease","volume":"137","author":"Sharma","year":"2017","journal-title":"Int. Rev. Neurobiol."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb1050","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/HTR.0000000000000280","article-title":"Branched chain amino acids (BCAAs) and traumatic brain injury: a systematic review","volume":"33","author":"Sharma","year":"2018","journal-title":"J. Head Trauma Rehabil."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb1055","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s12035-017-0742-9","article-title":"Co-administration of TiO2 nanowired mesenchymal stem cells with cerebrolysin potentiates neprilysin level and reduces brain pathology in Alzheimer's disease","volume":"55","author":"Sharma","year":"2018","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1060","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/bs.irn.2019.06.006","article-title":"Anesthetics influence concussive head injury induced blood-brain barrier breakdown, brain edema formation, cerebral blood flow, serotonin levels, brain pathology and functional outcome","volume":"146","author":"Sharma","year":"2019","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1065","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/bs.pbr.2020.09.010","article-title":"Mild traumatic brain injury exacerbates Parkinson's disease induced hemeoxygenase-2 expression and brain pathology: neuroprotective effects of co-administration of TiO(2) nanowired mesenchymal stem cells and cerebrolysin","volume":"258","author":"Sharma","year":"2020","journal-title":"Prog. Brain Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.pbr.2020.09.003","article-title":"Concussive head injury exacerbates neuropathology of sleep deprivation: superior neuroprotection by co-administration of TiO(2)-nanowired cerebrolysin, alpha-melanocyte-stimulating hormone, and mesenchymal stem cells","volume":"258","author":"Sharma","year":"2020","journal-title":"Prog. Brain Res."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb1075","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1136\/practneurol-2015-001087","article-title":"Concussion is confusing us all","volume":"15","author":"Sharp","year":"2015","journal-title":"Pract. Neurol."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb1080","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.apmr.2019.10.179","article-title":"Management of concussion and mild traumatic brain injury: a synthesis of practice guidelines","volume":"101","author":"Silverberg","year":"2020","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"7","key":"10.1016\/bs.pbr.2021.06.016_bb1085","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1016\/0306-4522(82)90035-5","article-title":"A note on the use of picric acid-paraformaldehyde-glutaraldehyde fixative for correlated light and electron microscopic immunocytochemistry","volume":"7","author":"Somogyi","year":"1982","journal-title":"Neuroscience"},{"key":"10.1016\/bs.pbr.2021.06.016_bb1090","doi-asserted-by":"crossref","first-page":"117112","DOI":"10.1016\/j.neuroimage.2020.117112","article-title":"Regional balance between glutamate+glutamine and GABA+ in the resting human brain","volume":"220","author":"Steel","year":"2020","journal-title":"Neuroimage"},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb1095","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1021\/acs.chemrestox.9b00121","article-title":"Cycloheterophyllin inhibits the release of glutamate from nerve terminals of the rat hippocampus","volume":"32","author":"Su","year":"2019","journal-title":"Chem. Res. Toxicol."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb1100","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s002210050574","article-title":"Representation of the midline trunk, bilateral arms, and shoulders in the monkey postcentral somatosensory cortex","volume":"123","author":"Taoka","year":"1998","journal-title":"Exp. Brain Res."},{"issue":"9","key":"10.1016\/bs.pbr.2021.06.016_bb1105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.ss6609a1","article-title":"Traumatic brain injury-related emergency department visits, hospitalizations, and deaths\u2014United States, 2007 and 2013","volume":"66","author":"Taylor","year":"2017","journal-title":"MMWR Surveill. Summ."},{"issue":"13\u201314","key":"10.1016\/bs.pbr.2021.06.016_bb1110","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.3109\/02699052.2015.1113561","article-title":"Impact of pre-injury family functioning and resources on self-reported post-concussive symptoms and functional outcomes in persons with mild TBI","volume":"30","author":"Temple","year":"2016","journal-title":"Brain Inj."},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb1115","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.neuint.2004.06.005","article-title":"NMDA-receptor mediated efflux of N-acetylaspartate: physiological and\/or pathological importance?","volume":"45","author":"Tranberg","year":"2004","journal-title":"Neurochem. Int."},{"issue":"6","key":"10.1016\/bs.pbr.2021.06.016_bb1120","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1080\/09602011.2018.1564674","article-title":"The factor structure of the quality of life inventory (QOLI) following traumatic brain injury","volume":"30","author":"Troup","year":"2020","journal-title":"Neuropsychol. Rehabil."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1125","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/0301-0082(95)00014-M","article-title":"N-acetylaspartate in neuropsychiatric disorders","volume":"46","author":"Tsai","year":"1995","journal-title":"Prog. Neurobiol."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb1130","first-page":"125","article-title":"Serotonin and amino acids: partners in delirium pathophysiology?","volume":"5","author":"van der Mast","year":"2000","journal-title":"Semin. Clin. Neuropsychiatry"},{"issue":"12","key":"10.1016\/bs.pbr.2021.06.016_bb1135","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1007\/s11136-018-1939-8","article-title":"Identifying the concepts contained within health-related quality of life outcome measures in concussion research using the international classification of functioning, disability, and health as a reference: a systematic review","volume":"27","author":"van Ierssel","year":"2018","journal-title":"Qual. Life Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1140","doi-asserted-by":"crossref","first-page":"153943","DOI":"10.1016\/j.metabol.2019.07.007","article-title":"Traumatic brain injury (TBI) in collision sports: possible mechanisms of transformation into chronic traumatic encephalopathy (CTE)","volume":"100S","author":"VanItallie","year":"2019","journal-title":"Metabolism"},{"key":"10.1016\/bs.pbr.2021.06.016_bb1145","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/3-211-30714-1_34","article-title":"Zinc protoporphyrin IX attenuates closed head injury-induced edema formation, blood-brain barrier disruption, and serotonin levels in the rat","volume":"96","author":"Vannemreddy","year":"2006","journal-title":"Acta Neurochir. Suppl."},{"issue":"29","key":"10.1016\/bs.pbr.2021.06.016_bb1150","doi-asserted-by":"crossref","first-page":"7727","DOI":"10.1523\/JNEUROSCI.0587-16.2016","article-title":"Glutamate-mediated blood-brain barrier opening: implications for neuroprotection and drug delivery","volume":"36","author":"Vazana","year":"2016","journal-title":"J. Neurosci."},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb1155","doi-asserted-by":"crossref","first-page":"e1854","DOI":"10.1038\/cddis.2015.226","article-title":"Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: a novel pharmacological strategy against brain injury","volume":"6","author":"Vercelli","year":"2015","journal-title":"Cell Death Dis."},{"issue":"8","key":"10.1016\/bs.pbr.2021.06.016_bb1160","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1080\/15389588.2015.1013188","article-title":"Concussion, diffuse axonal injury, and AIS4+ head injury in motor vehicle crashes","volume":"16","author":"Viano","year":"2015","journal-title":"Traffic Inj. Prev."},{"issue":"7","key":"10.1016\/bs.pbr.2021.06.016_bb1165","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s11916-015-0506-z","article-title":"Update on the epidemiology of concussion\/mild traumatic brain injury","volume":"19","author":"Voss","year":"2015","journal-title":"Curr. Pain Headache Rep."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1170","doi-asserted-by":"crossref","first-page":"890","DOI":"10.2741\/4426","article-title":"Traumatic brain injury: a review of characteristics, molecular basis and management","volume":"21","author":"Wang","year":"2016","journal-title":"Front. Biosci. (Landmark Ed.)"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb1175","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12974-016-0786-1","article-title":"Inflammation in epileptogenesis after traumatic brain injury","volume":"14","author":"Webster","year":"2017","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/bs.pbr.2021.06.016_bb1180","first-page":"69","article-title":"Glutamate and aspartate as neurotransmitters for the auditory nerve","volume":"27","author":"Wenthold","year":"1981","journal-title":"Adv. Biochem. Psychopharmacol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1185","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0079-6123(08)62038-5","article-title":"Heat shock protein response in the central nervous system following hyperthermia","volume":"115","author":"Westman","year":"1998","journal-title":"Prog. Brain Res."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1190","first-page":"31","article-title":"Mechanical and excitotoxic lesion of motoneurons: effects of neurotrophins and ciliary neurotrophic factor on survival and regeneration","volume":"73","author":"Wiese","year":"1999","journal-title":"Acta Neurochir. Suppl."},{"issue":"4541","key":"10.1016\/bs.pbr.2021.06.016_bb1195","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1126\/science.6121375","article-title":"Aspartate: possible neurotransmitter in cerebellar climbing fibers","volume":"216","author":"Wiklund","year":"1982","journal-title":"Science"},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb1200","article-title":"Excitatory amino acid inhibitors for traumatic brain injury","volume":"2003","author":"Willis","year":"2004","journal-title":"Cochrane Database Syst. Rev."},{"issue":"1","key":"10.1016\/bs.pbr.2021.06.016_bb1205","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0168-0102(94)90072-8","article-title":"Opioid receptors influence spinal cord electrical activity and edema formation following spinal cord injury: experimental observations using naloxone in the rat","volume":"21","author":"Winkler","year":"1994","journal-title":"Neurosci. Res."},{"issue":"4","key":"10.1016\/bs.pbr.2021.06.016_bb1265","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1161\/STROKEAHA.113.004475","article-title":"Excitotoxicity and metabolic changes in association with infarct progression","volume":"45","author":"Woitzik","year":"2014","journal-title":"Stroke"},{"key":"10.1016\/bs.pbr.2021.06.016_bb1210","doi-asserted-by":"crossref","first-page":"101730","DOI":"10.1016\/j.pneurobio.2019.101730","article-title":"Traumatic brain injury triggers APP and tau cleavage by delta-secretase, mediating Alzheimer's disease pathology","volume":"185","author":"Wu","year":"2020","journal-title":"Prog. Neurobiol."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb1215","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1152\/jn.00896.2017","article-title":"Glutamate and GABA concentrations following mild traumatic brain injury: a pilot study","volume":"120","author":"Yasen","year":"2018","journal-title":"J. Neurophysiol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1220","doi-asserted-by":"crossref","first-page":"683","DOI":"10.3389\/fneur.2020.00683","article-title":"Excitability, inhibition, and neurotransmitter levels in the motor cortex of symptomatic and asymptomatic individuals following mild traumatic brain injury","volume":"11","author":"Yasen","year":"2020","journal-title":"Front. Neurol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1225","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/400_2007_029","article-title":"Regulation of excitation by glycine receptors","volume":"44","author":"Ye","year":"2008","journal-title":"Results Probl. Cell Differ."},{"issue":"3","key":"10.1016\/bs.pbr.2021.06.016_bb1230","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/0306-4522(96)00149-2","article-title":"Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity","volume":"74","author":"You","year":"1996","journal-title":"Neuroscience"},{"issue":"10","key":"10.1016\/bs.pbr.2021.06.016_bb1235","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/j.lpm.2017.08.013","article-title":"Depression and sports-related concussion: a systematic review","volume":"46","author":"Yrondi","year":"2017","journal-title":"Presse Med."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1240","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/B978-0-444-63954-7.00030-6","article-title":"Chronic traumatic encephalopathy: fluid biomarkers","volume":"158","author":"Zetterberg","year":"2018","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/bs.pbr.2021.06.016_bb1245","doi-asserted-by":"crossref","first-page":"576389","DOI":"10.3389\/fnins.2020.576389","article-title":"Glycine-histidine-lysine (GHK) alleviates astrocytes injury of intracerebral hemorrhage via the Akt\/miR-146a-3p\/AQP4 pathway","volume":"14","author":"Zhang","year":"2020","journal-title":"Front. Neurosci."},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb1250","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/00075197-200303000-00013","article-title":"L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent","volume":"6","author":"Zhong","year":"2003","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"issue":"2","key":"10.1016\/bs.pbr.2021.06.016_bb1255","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0306-4522(91)90125-8","article-title":"Altered glial fibrillary acidic protein immunoreactivity in rat brain following chronic hypoxia","volume":"40","author":"Zimmer","year":"1991","journal-title":"Neuroscience"}],"container-title":["Progress in Brain Research","Brain Protection Strategies and Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S007961232100162X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S007961232100162X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:11:43Z","timestamp":1786119103000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S007961232100162X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"ISBN":["9780323989275"],"references-count":254,"URL":"https:\/\/doi.org\/10.1016\/bs.pbr.2021.06.016","relation":{},"ISSN":["0079-6123"],"issn-type":[{"value":"0079-6123","type":"print"}],"subject":[],"published":{"date-parts":[[2021]]}}}