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Behav."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0385","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0361-9230(99)00192-6","article-title":"Ventrolateral periacqueductal gray matter and the control of tonic immobility","volume":"50","author":"Monassi","year":"1999","journal-title":"Brain Res. Bull."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0390","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0006-8993(86)91367-3","article-title":"Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission","volume":"397","author":"Moreau","year":"1986","journal-title":"Brain Res."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0395","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0006-8993(89)90116-9","article-title":"Site-specific postural and locomotor changes evoked in awake, freely moving intact cats by stimulating the brainstem","volume":"505","author":"Mori","year":"1989","journal-title":"Brain Res."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0400","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1002\/cne.21486","article-title":"Serotonin-immunoreactive axon terminals innervate pyramidal cells and interneurons in the rat basolateral amygdala","volume":"505","author":"Muller","year":"2007","journal-title":"J Comp Neurol"},{"issue":"Suppl. 17","key":"10.1016\/bs.pbr.2022.02.008_bb0405","doi-asserted-by":"crossref","first-page":"S84","DOI":"10.1093\/sleep\/17.suppl_8.S84","article-title":"Neuropharmacology and neurochemistry of canine narcolepsy","volume":"17","author":"Nishino","year":"1994","journal-title":"Sleep"},{"issue":"7","key":"10.1016\/bs.pbr.2022.02.008_bb0410","doi-asserted-by":"crossref","first-page":"4806","DOI":"10.1523\/JNEUROSCI.15-07-04806.1995","article-title":"Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy","volume":"15","author":"Nishino","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0415","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0024-3205(83)90447-2","article-title":"Opioid peptide-like immunoreactivity localized in GABAergic neurons of rat neostriatum and central amygdaloid nucleus","volume":"33","author":"Oertel","year":"1983","journal-title":"Life Sci."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0420","doi-asserted-by":"crossref","first-page":"3489","DOI":"10.1097\/00001756-199711100-00015","article-title":"The lateral hypothalamus in the modulation of tonic immobility in guinea pigs","volume":"8","author":"Oliveira","year":"1997","journal-title":"Neuroreport"},{"key":"10.1016\/bs.pbr.2022.02.008_bb0425","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/S0031-9384(97)00351-X","article-title":"Participation of the medial and anterior hypothalamus in the modulation of tonic immobility in guinea pigs","volume":"62","author":"Oliveira","year":"1997","journal-title":"Physiol. Behav."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0430","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S1389-9457(02)00037-0","article-title":"Medical hypothesis. Cataplexy: \u2018tonic immobility\u2019 rather than \u2018REM-sleep atonia\u2019?","volume":"3","author":"Overeem","year":"2002","journal-title":"Sleep Med."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0435","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0006-8993(00)02972-3","article-title":"Afferents to the central nucleus of the amygdala and functional subdivisions of the periaqueductal gray: neuroanatomical substrates for affective behavior","volume":"887","author":"Paredes","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0440","first-page":"6991","article-title":"A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains","author":"Peyron","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0445","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.physbeh.2008.02.013","article-title":"Modulation of tonic immobility in guinea pig PAG by homocysteic acid, a glutamate agonist","volume":"94","author":"Ramos","year":"2007","journal-title":"Physiol. Behav."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0450","series-title":"Handbook of Clinical and Experimental Hypnosis","first-page":"550","article-title":"Comparative aspects of hypnosis","author":"Ratner","year":"1967"},{"key":"10.1016\/bs.pbr.2022.02.008_bb0455","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/00005053-198210000-00004","article-title":"Induced immobility in normal and pointer dogs","volume":"170","author":"Reese","year":"1982","journal-title":"J. Nerv. Ment. Dis."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0460","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/cne.903030111","article-title":"Connections between the central nucleus of the amygdala and midbrain periaqueductal gray: topography and reciprocity","volume":"303","author":"Rizvi","year":"1991","journal-title":"J Comp Neurol"},{"key":"10.1016\/bs.pbr.2022.02.008_bb0465","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/0014-4886(69)90051-X","article-title":"Relaxation and sleep induced by warming of preoptic region and anterior hypothalamic in cats","volume":"25","author":"Roberson","year":"1969","journal-title":"Exp. Neurol."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0470","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.euroneuro.2007.02.015","article-title":"5-HT2 mechanisms of the basolateral nucleous of amygdala enhance conditioned fear and impair unconditioned fear induced by stimulation of the dorsal periaqueductal gray","volume":"17","author":"Ruiz-Martinez","year":"2007","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0475","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/0091-3057(95)00153-N","article-title":"Regulation of anxiety by GABAA receptors in the rat amygdala","volume":"52","author":"Sanders","year":"1995","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0480","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/cne.902530302","article-title":"Cholinergic neurons of the laterodorsal tegmental nucleus: efferent and afferent connections","volume":"15","author":"Satoh","year":"1986","journal-title":"Comp. Neurol."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0485","first-page":"34","article-title":"Hypocretinergic interaction with serotonergic system regulate REM sleep and cataplexy","volume":"6","author":"Seifinejad","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0490","series-title":"Punishment and Aversive Behavior","first-page":"256","article-title":"Unpredictable and uncontrollable aversive events","volume":"25","author":"Seligman","year":"1971"},{"key":"10.1016\/bs.pbr.2022.02.008_bb0495","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S0006-8993(97)00433-2","article-title":"Serotonin 5-HT1A and 5-HT271C receptors in the midbrain periaqueductal gray differentially modulate defensive rage elicited from the medial hypothalamus of the cat","volume":"765","author":"Shaikh","year":"1997","journal-title":"Brain Res."},{"issue":"8","key":"10.1016\/bs.pbr.2022.02.008_bb0500","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.biopsych.2009.12.035","article-title":"Orexin signaling via the orexin 1 receptor mediates operant responding for food reinforcement","volume":"67","author":"Sharf","year":"2010","journal-title":"Biol. 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I. Retrograde tracing studies","volume":"321","author":"Steininger","year":"1992","journal-title":"J Comp Neurol"},{"key":"10.1016\/bs.pbr.2022.02.008_bb0525","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.5665\/sleep.2972","article-title":"Influence of inhibitory serotonergic inputs to orexin\/hypocretin neurons on the diurnal rhythm of sleep and wakefulness","volume":"36","author":"Tabuchi","year":"2013","journal-title":"Sleep"},{"key":"10.1016\/bs.pbr.2022.02.008_bb0530","series-title":"Advances in Pain Research and Therapy 1","first-page":"781","article-title":"Modulation of EEG and unit discharges of deep structures of brain during acupunctural stimulation and hypnosis of rabbits","author":"Takeshige","year":"1976"},{"key":"10.1016\/bs.pbr.2022.02.008_bb0535","first-page":"551","article-title":"Neuro-chemical analysis of hypothalamic and midbrain effector centers regulating emotional behavior","volume":"21","author":"Vahing","year":"1971","journal-title":"J. High. Nerv. Act."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0540","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0361-9230(87)90015-3","article-title":"The immunohistochemical localization of choline acetyltransferase in the cat brain","volume":"18","author":"Vincent","year":"1987","journal-title":"Brain Res. Bull."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0545","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1523\/JNEUROSCI.01-02-00176.1981","article-title":"Autoradiographic localization of muscarinic receptors in rat brainstem","volume":"1","author":"Wamsley","year":"1981","journal-title":"J. Neurosci."},{"key":"10.1016\/bs.pbr.2022.02.008_bb0550","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3758\/BF03326579","article-title":"Effects of scopolamine ad physostigmine on tonic immobility in ducks and guinea pigs","volume":"4","author":"Woodruff","year":"1976","journal-title":"Physiol. 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