{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:48:26Z","timestamp":1791877706099,"version":"4.3.4"},"reference-count":332,"publisher":"Elsevier","isbn-type":[{"value":"9780323991070","type":"print"}],"license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1016\/bs.pbr.2022.10.004","type":"book-chapter","created":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T20:16:23Z","timestamp":1675455383000},"page":"165-215","source":"Crossref","is-referenced-by-count":19,"title":["Evolutionary and genomic perspectives of brain aging and neurodegenerative diseases"],"prefix":"10.1016","author":[{"given":"Brier A.","family":"Rigby Dames","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huseyin","family":"Kilili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine J.","family":"Charvet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"D\u00edaz-Barba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Proulx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra A.","family":"de Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Araxi O.","family":"Urrutia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0010","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3390\/genes10030222","article-title":"The genetic variability of APOE in different human populations and its implications for longevity","volume":"10","author":"Abondio","year":"2019","journal-title":"Genes"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0015","first-page":"e569","article-title":"Correlation between micro-hardness and mineral content in healthy human enamel","volume":"9","author":"Akkus","year":"2017","journal-title":"J. Clin. Exp. Dent."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0020","series-title":"Gerontology","article-title":"Ageing Process and Physiological Changes","author":"Amarya","year":"2018"},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb0025","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.neurobiolaging.2010.11.001","article-title":"Gray matter atrophy rate as a marker of disease progression in AD","volume":"33","author":"Anderson","year":"2012","journal-title":"Neurobiol. Aging"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0030","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/WAD.0b013e3182163b62","article-title":"Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment (MCI), and Alzheimer disease","volume":"26","author":"Apostolova","year":"2012","journal-title":"Alzheimer Dis. Assoc. Disord."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0035","doi-asserted-by":"crossref","first-page":"134","DOI":"10.4161\/cib.18761","article-title":"The post-mitotic state in neurons correlates with a stable nuclear higher-order structure","volume":"5","author":"Aranda-Anzaldo","year":"2012","journal-title":"Commun. Integr. Biol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.117289","article-title":"Associations between cognitive and brain volume changes in cognitively normal older adults","volume":"223","author":"Armstrong","year":"2020","journal-title":"Neuroimage"},{"issue":"11","key":"10.1016\/bs.pbr.2022.10.004_bb0045","doi-asserted-by":"crossref","DOI":"10.1002\/ajp.23254","article-title":"Studies of aging nonhuman primates illuminate the etiology of early-stage Alzheimer\u2019s-like neuropathology: an evolutionary perspective","volume":"83","author":"Arnsten","year":"2021","journal-title":"Am. J. Primatol."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0050","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/alz.12192","article-title":"Hypothesis: tau pathology is an initiating factor in sporadic Alzheimer's disease","volume":"17","author":"Arnsten","year":"2021","journal-title":"Alzheimers Dement."},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb0055","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1097\/00004647-200110000-00001","article-title":"An energy budget for signaling in the grey matter of the brain","volume":"21","author":"Attwell","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0060","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1203\/PDR.0b013e3181a9eafb","article-title":"Oxygen toxicity and reactive oxygen species: the devil is in the details","volume":"66","author":"Auten","year":"2009","journal-title":"Pediatr. Res."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0065","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.neuroimage.2014.06.053","article-title":"Age-related effects in the neocortical organization of chimpanzees: gray and white matter volume, cortical thickness, and gyrification","volume":"101","author":"Autrey","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0070","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.683459","article-title":"The ageing brain: molecular and cellular basis of neurodegeneration","volume":"9","author":"Azam","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0075","series-title":"Evolution of Nervous Systems","first-page":"223","article-title":"The Role of Endocasts in the Study of Brain Evolution","author":"Balanoff","year":"2016"},{"issue":"JAN","key":"10.1016\/bs.pbr.2022.10.004_bb0080","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3389\/fendo.2018.00790","article-title":"Hallmarks of aging: an autophagic perspective","volume":"10","author":"Barbosa","year":"2019","journal-title":"Front. Endocrinol."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0085","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.jhevol.2007.08.012","article-title":"Life history costs and benefits of encephalization: a comparative test using data from long-term studies of primates in the wild","volume":"54","author":"Barrickman","year":"2008","journal-title":"J. Hum. Evol."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1577","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/evan.21831","article-title":"Metabolic changes in human brain evolution","volume":"29","author":"Bauernfeind","year":"2020","journal-title":"Evol. Anthropol."},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb0090","doi-asserted-by":"crossref","first-page":"3286","DOI":"10.1093\/brain\/awx243","article-title":"Tau pathology and neurodegeneration contribute to cognitive impairment in Alzheimer's disease","volume":"140","author":"Bejanin","year":"2017","journal-title":"Brain"},{"issue":"40","key":"10.1016\/bs.pbr.2022.10.004_bb0095","doi-asserted-by":"crossref","first-page":"15605","DOI":"10.1073\/pnas.0806883105","article-title":"Gene expression changes in the course of normal brain aging are sexually dimorphic","volume":"105","author":"Berchtold","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0100","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1016\/j.neurobiolaging.2012.11.024","article-title":"Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease","volume":"34","author":"Berchtold","year":"2013","journal-title":"Neurobiol. Aging"},{"issue":"24","key":"10.1016\/bs.pbr.2022.10.004_bb0105","doi-asserted-by":"crossref","first-page":"3736","DOI":"10.4161\/cc.27188","article-title":"Aging is not programmed: genetic pseudo-program is a shadow of developmental growth","volume":"12","author":"Blagosklonny","year":"2013","journal-title":"Cell Cycle"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0110","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3389\/fmech.2021.705653","article-title":"Brain shape changes associated with cerebral atrophy in healthy aging and Alzheimer's disease","volume":"7","author":"Blinkouskaya","year":"2021","journal-title":"Front. Mech. Eng."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0115","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/ajhb.10038","article-title":"Antiquity of postreproductive life: are there modern impacts on hunter-gatherer postreproductive life spans?","volume":"14","author":"Blurton Jones","year":"2002","journal-title":"Am. J. Hum. Biol."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0120","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/nrneurol.2011.21","article-title":"White matter lesions in Parkinson disease","volume":"7","author":"Bohnen","year":"2011","journal-title":"Nat. Rev. Neurol."},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb0125","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1002\/mds.25135","article-title":"Living on the edge with too many mouths to feed: why dopamine neurons die","volume":"27","author":"Bolam","year":"2012","journal-title":"Mov. Disord."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0130","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.3389\/fneur.2018.01021","article-title":"A meta-analysis of \u03b1-synuclein multiplication in familial parkinsonism","volume":"9","author":"Book","year":"2018","journal-title":"Front. Neurol."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0135","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological stageing of Alzheimer-related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0140","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s00401-006-0127-z","article-title":"Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry","volume":"112","author":"Braak","year":"2006","journal-title":"Acta Neuropathol."},{"issue":"23","key":"10.1016\/bs.pbr.2022.10.004_bb0145","doi-asserted-by":"crossref","first-page":"6139","DOI":"10.1093\/hmg\/ddu334","article-title":"Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies","volume":"23","author":"Bras","year":"2014","journal-title":"Hum. Mol. Genet."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0150","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3233\/JAD-122299","article-title":"Alzheimer's disease: the downside of a highly evolved parietal lobe?","volume":"35","author":"Bruner","year":"2013","journal-title":"J. Alzheimers Dis."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0155","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/s00429-015-1172-y","article-title":"Evidence for expansion of the precuneus in human evolution","volume":"222","author":"Bruner","year":"2017","journal-title":"Brain Struct. Funct."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0160","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/jmammal\/gyz043","article-title":"The allometry of brain size in mammals","volume":"100","author":"Burger","year":"2019","journal-title":"J. Mammal."},{"issue":"8","key":"10.1016\/bs.pbr.2022.10.004_bb0165","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1038\/ng.3911","article-title":"Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk","volume":"49","author":"Capellini","year":"2017","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0021545","article-title":"The reality of Neandertal symbolic behavior at the Grotte du Renne, Arcy-sur-Cure, France","volume":"6","author":"Caron","year":"2011","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0175","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/ajpa.20360","article-title":"Is human longevity a consequence of cultural change or modern biology?","volume":"129","author":"Caspari","year":"2006","journal-title":"Am. J. Phys. Anthropol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0180","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.neurobiolaging.2018.10.015","article-title":"Postmitotic cell longevity\u2013associated genes: a transcriptional signature of postmitotic maintenance in neural tissues","volume":"74","author":"Castillo-Morales","year":"2019","journal-title":"Neurobiol. Aging"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0185","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00441-018-2854-6","article-title":"Is Lewy pathology in the human nervous system chiefly an indicator of neuronal protection or of toxicity?","volume":"373","author":"Chartier","year":"2018","journal-title":"Cell Tissue Res."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1574","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2018.00383","article-title":"Alzheimer's disease and type 2 diabetes: a critical assessment of the shared pathological traits","volume":"12","author":"Chatterjee","year":"2018","journal-title":"Front. Neurosci."},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb0190","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1080\/00207454.2020.1766459","article-title":"Cortical thickness and gyrification index measuring cognition in Parkinson's disease","volume":"131","author":"Chaudhary","year":"2021","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0195","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3389\/fcell.2020.00200","article-title":"Mitophagy: an emerging role in aging and age-associated diseases","volume":"8","author":"Chen","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms22052283","article-title":"Involvement of cholinergic, adrenergic, and glutamatergic network modulation with cognitive dysfunction in alzheimer's disease","volume":"22","author":"Cheng","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1573","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1002\/mds.28551","article-title":"Type 2 diabetes as a determinant of Parkinson's disease risk and progression","volume":"36","author":"Chohan","year":"2021","journal-title":"Mov. Disord."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0205","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s10059-013-0297-1","article-title":"Regulation of SIRT1 by microRNAs","volume":"36","author":"Choi","year":"2013","journal-title":"Mol. Cells"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0210","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.nbd.2006.08.021","article-title":"Age-associated increases of \u03b1-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: is this the target for Parkinson's disease?","volume":"25","author":"Chu","year":"2007","journal-title":"Neurobiol. Dis."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0215","first-page":"1","article-title":"Comparison of mechanical property and role between enamel and dentin in the human teeth","volume":"5","author":"Chun","year":"2014","journal-title":"J. Dent. Biomech."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0220","doi-asserted-by":"crossref","first-page":"367","DOI":"10.14336\/AD.2018.0324","article-title":"Redefining chronic inflammation in aging and age-related diseases: proposal of the senoinflammation concept","volume":"10","author":"Chung","year":"2019","journal-title":"Aging Dis."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0225","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1007\/s12035-019-01819-y","article-title":"Alterations of transcription of genes coding anti-oxidative and mitochondria-related proteins in amyloid \u03b2 toxicity: relevance to alzheimer's disease","volume":"57","author":"Cie\u015blik","year":"2020","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0230","series-title":"Genetics, Neurology, Behavior, and Diet in Parkinson's Disease","first-page":"3","article-title":"Leucine-rich repeat kinase 2 (LRRK2) and Parkinson's disease: from genetics to pathobiology","author":"Cogo","year":"2020"},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0235","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/nrn3039","article-title":"Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates","volume":"12","author":"Collier","year":"2011","journal-title":"Nat. Rev. Neurosci."},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb0240","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1002\/mds.27037","article-title":"Aging and Parkinson's disease: different sides of the same coin?","volume":"32","author":"Collier","year":"2017","journal-title":"Mov. Disord."},{"issue":"1\u20132","key":"10.1016\/bs.pbr.2022.10.004_bb1566","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1159\/000313659","volume":"8","author":"Cornutiu","year":"2011","journal-title":"J. Neurodegener. Dis."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0245","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.neurobiolaging.2017.12.011","article-title":"Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer's disease","volume":"64","author":"Cramer","year":"2018","journal-title":"Neurobiol. Aging"},{"issue":"9","key":"10.1016\/bs.pbr.2022.10.004_bb0250","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1002\/humu.22117","article-title":"Locus-specific mutation databases for neurodegenerative brain diseases","volume":"33","author":"Cruts","year":"2012","journal-title":"Hum. Mutat."},{"issue":"19","key":"10.1016\/bs.pbr.2022.10.004_bb0255","doi-asserted-by":"crossref","first-page":"15132","DOI":"10.18632\/oncotarget.23738","article-title":"The genes associated with early-onset Alzheimer's disease","volume":"9","author":"Dai","year":"2018","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0260","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/gbe\/evaa250","article-title":"The population-specific impact of neandertal introgression on human disease","volume":"13","author":"Dannemann","year":"2021","journal-title":"Genome Biol. Evol."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0265","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/cshperspect.a008813","article-title":"Regulation and function of autophagy during cell survival and cell death","volume":"4","author":"Das","year":"2012","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb0270","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/j.neurobiolaging.2014.01.148","article-title":"Apolipoprotein D takes center stage in the stress response of the aging and degenerative brain","volume":"35","author":"Dassati","year":"2014","journal-title":"Neurobiol. Aging"},{"issue":"MAY","key":"10.1016\/bs.pbr.2022.10.004_bb0275","first-page":"94","article-title":"Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer's disease","volume":"7","author":"de Felice","year":"2015","journal-title":"Front. Aging Neurosci."},{"issue":"9","key":"10.1016\/bs.pbr.2022.10.004_bb0280","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1136\/jnnp.2004.053686","article-title":"Progression of cerebral white matter lesions in Alzheimer's disease: a new window for therapy?","volume":"76","author":"De Leeuw","year":"2005","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.exger.2005.09.002","article-title":"Cells discover fire: employing reactive oxygen species in development and consequences for aging","volume":"41","author":"De Magalh\u00e3es","year":"2006","journal-title":"Exp. Gerontol."},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb0290","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/bioinformatics\/btp073","article-title":"Meta-analysis of age-related gene expression profiles identifies common signatures of aging","volume":"25","author":"de Magalh\u00e3es","year":"2009","journal-title":"Bioinformatics"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0295","doi-asserted-by":"crossref","first-page":"775","DOI":"10.3233\/JPD-191600","article-title":"Regional structural hippocampal differences between dementia with Lewy bodies and Parkinson's disease","volume":"9","author":"De Schipper","year":"2019","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0300","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.neurobiolaging.2019.05.004","article-title":"Age- and disease-related cerebral white matter changes in patients with Parkinson's disease","volume":"80","author":"de Schipper","year":"2019","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0305","series-title":"Evolution of Nervous Systems","first-page":"291","article-title":"The hominin fossil record and the emergence of the modern human central nervous system","author":"de Sousa","year":"2007"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0310","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.bbamcr.2010.08.007","article-title":"Mitophagy and Parkinson's disease: the PINK1-parkin link","volume":"1813","author":"Deas","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb0315","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1111\/evo.13633","article-title":"Encephalization and longevity evolved in a correlated fashion in Euarchontoglires but not in other mammals","volume":"72","author":"DeCasien","year":"2018","journal-title":"Evolution"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0320","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/wdev.301","article-title":"Serotonin neuron development: shaping molecular and structural identities","volume":"7","author":"Deneris","year":"2018","journal-title":"Wiley Interdiscip. Rev. Dev. Biol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0325","doi-asserted-by":"crossref","first-page":"712","DOI":"10.3389\/fevo.2021.742639","article-title":"When and why did human brains decrease in size? A new change-point analysis and insights from brain evolution in ants","volume":"9","author":"DeSilva","year":"2021","journal-title":"Front. Ecol. Evol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0330","series-title":"Breastfeeding","first-page":"39","article-title":"A Time to Wean: The Hominid Blueprint for the Natural Age of Weaning in Modern Human Populations","author":"Dettwyler","year":"1995"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0335","first-page":"1","article-title":"Compartmentalized signaling in aging and neurodegeneration","volume":"10","author":"Di Benedetto","year":"2021","journal-title":"Cell"},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb0340","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000006212","article-title":"APOE \u025b4 is associated with severity of Lewy body pathology independent of Alzheimer pathology","volume":"91","author":"Dickson","year":"2018","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0345","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/mds.27628","article-title":"Parkinson's disease: is it a consequence of human brain evolution?","volume":"34","author":"Diederich","year":"2019","journal-title":"Mov. Disord."},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb0350","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.tins.2020.05.001","article-title":"The evolution-driven signature of Parkinson's disease","volume":"43","author":"Diederich","year":"2020","journal-title":"Trends Neurosci."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0355","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s11692-019-09471-z","article-title":"Multiple components of phylogenetic non-stationarity in the evolution of brain size in fossil hominins","volume":"46","author":"Diniz-Filho","year":"2019","journal-title":"Evol. Biol."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1576","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/j.jas.2007.10.009","article-title":"On the elimination of extraneous DNA in fossil human teeth with hypochlorite","volume":"35","author":"Dissing","year":"2008","journal-title":"J. Archaeol. Sci."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0360","doi-asserted-by":"crossref","first-page":"125","DOI":"10.2307\/4444260","article-title":"Nothing in biology makes sense except in the light of evolution","volume":"35","author":"Dobzhansky","year":"1973","journal-title":"Am. Biol. Teach."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0365","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/acel.12503","article-title":"Has gene duplication impacted the evolution of Eutherian longevity?","volume":"15","author":"Doherty","year":"2016","journal-title":"Aging Cell"},{"issue":"s1","key":"10.1016\/bs.pbr.2022.10.004_bb0370","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.3233\/JPD-181474","article-title":"The emerging evidence of the Parkinson pandemic","volume":"8","author":"Dorsey","year":"2018","journal-title":"J. Parkinsons Dis."},{"issue":"22","key":"10.1016\/bs.pbr.2022.10.004_bb0375","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1212\/WNL.0b013e3181a82634","article-title":"Longitudinal pattern of regional brain volume change differentiates normal aging from MCI","volume":"72","author":"Driscoll","year":"2009","journal-title":"Neurology"},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb0380","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1093\/brain\/awx258","article-title":"PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease","volume":"140","author":"Du","year":"2017","journal-title":"Brain"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0385","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1037\/h0099301","article-title":"Behavioral flexibility in life history strategies: the role of life expectancy","volume":"4","author":"Dunkel","year":"2010","journal-title":"J. Soc. Evol. Cult. Psychol."},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb0390","first-page":"1","article-title":"How to become a primate fossil","volume":"6","author":"Dunsworth","year":"2015","journal-title":"Nat. Edu. Knowledge"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0395","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.neurobiolaging.2017.07.006","article-title":"Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease","volume":"59","author":"Edler","year":"2017","journal-title":"Neurobiol. Aging"},{"issue":"18","key":"10.1016\/bs.pbr.2022.10.004_bb0400","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1002\/cne.24484","article-title":"Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees","volume":"526","author":"Edler","year":"2018","journal-title":"J Comp Neurol"},{"issue":"1811","key":"10.1016\/bs.pbr.2022.10.004_bb0405","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2019.0619","article-title":"Neuron loss associated with age but not Alzheimer's disease pathology in the chimpanzee brain","volume":"375","author":"Edler","year":"2020","journal-title":"Philos. Trans. R. Soc. B: Biol. Sci."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0410","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-31047-8","article-title":"Analyses of ovarian activity reveal repeated evolution of post-reproductive lifespans in toothed whales","volume":"8","author":"Ellis","year":"2018","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0415","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/(SICI)1096-9861(19981116)401:2<253::AID-CNE7>3.0.CO;2-X","article-title":"Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys","volume":"401","author":"Emborg","year":"1998","journal-title":"J Comp Neurol"},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0420","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s00109-012-0901-4","article-title":"Functional primate genomics\u2014leveraging the medical potential","volume":"90","author":"Enard","year":"2012","journal-title":"J. Mol. Med."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0425","first-page":"1","article-title":"The evolution of aging","volume":"3","author":"Fabian","year":"2011","journal-title":"Nat. Edu. Knowledge"},{"issue":"MAY","key":"10.1016\/bs.pbr.2022.10.004_bb0430","article-title":"Interpreting sulci on hominin endocasts: old hypotheses and new findings","volume":"8","author":"Falk","year":"2014","journal-title":"Front. Hum. Neurosci."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0435","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2174\/1570159X13666150716165726","article-title":"Alzheimer's disease: targeting the cholinergic system","volume":"14","author":"Ferreira-Vieira","year":"2016","journal-title":"Curr. Neuropharmacol."},{"issue":"6005","key":"10.1016\/bs.pbr.2022.10.004_bb0440","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1126\/science.1199139","article-title":"Change in the brain's white matter","volume":"330","author":"Fields","year":"2010","journal-title":"Science"},{"issue":"Suppl. 1","key":"10.1016\/bs.pbr.2022.10.004_bb0445","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1073\/pnas.0909606106","article-title":"Evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition","volume":"107","author":"Finch","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0450","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1007\/s11357-011-9355-9","article-title":"Primate aging in the mammalian scheme: the puzzle of extreme variation in brain aging","volume":"34","author":"Finch","year":"2012","journal-title":"Age"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0455","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.neurobiolaging.2014.10.025","article-title":"Commentary: is Alzheimer's disease uniquely human?","volume":"36","author":"Finch","year":"2015","journal-title":"Neurobiol. Aging"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0460","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0197-4580(99)00053-6","article-title":"The evolution of Alzheimer disease, the reproductive schedule, and apoE isoforms","volume":"20","author":"Finch","year":"1999","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0465","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.pneurobio.2014.02.004","article-title":"What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus","volume":"117","author":"Fjell","year":"2014","journal-title":"Prog. Neurobiol."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0470","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/cercor\/bhs379","article-title":"Accelerating cortical thinning: unique to dementia or universal in aging?","volume":"24","author":"Fjell","year":"2014","journal-title":"Cereb. Cortex"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0475","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1037\/neu0000447","article-title":"Brain volume change and cognitive trajectories in aging","volume":"32","author":"Fletcher","year":"2018","journal-title":"Neuropsychology"},{"issue":"6100","key":"10.1016\/bs.pbr.2022.10.004_bb0480","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1126\/science.1224198","article-title":"Adaptive prolonged postreproductive life span in killer whales","volume":"337","author":"Foster","year":"2012","journal-title":"Science"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0485","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.arr.2018.07.008","article-title":"\u2018Evolutionary medicine\u2019 perspectives on Alzheimer's Disease: review and new directions","volume":"47","author":"Fox","year":"2018","journal-title":"Ageing Res. Rev."},{"issue":"Suppl_1","key":"10.1016\/bs.pbr.2022.10.004_bb0490","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1093\/gerona\/glu057","article-title":"Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases","volume":"69","author":"Franceschi","year":"2014","journal-title":"J. Gerontol. A Biol. Sci."},{"issue":"11","key":"10.1016\/bs.pbr.2022.10.004_bb0495","doi-asserted-by":"crossref","first-page":"23299","DOI":"10.1002\/ajp.23299","article-title":"Comparative neuropathology in aging primates: a perspective","volume":"83","author":"Freire-Cobo","year":"2021","journal-title":"Am. J. Primatol."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0500","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s10522-018-9750-z","article-title":"Gene expression hallmarks of cellular ageing","volume":"19","author":"Frenk","year":"2018","journal-title":"Biogerontology"},{"issue":"42","key":"10.1016\/bs.pbr.2022.10.004_bb0505","doi-asserted-by":"crossref","first-page":"8098","DOI":"10.1126\/sciadv.abc8098","article-title":"Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy","volume":"6","author":"Fung","year":"2020","journal-title":"Sci. Adv."},{"issue":"7448","key":"10.1016\/bs.pbr.2022.10.004_bb0510","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/nature12100","article-title":"Physiology: inflammation links ageing to the brain","volume":"497","author":"Gabuzda","year":"2013","journal-title":"Nature"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0515","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.68231","article-title":"Apoe4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical amerindian subsistence population","volume":"10","author":"Garcia","year":"2021","journal-title":"Elife"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0520","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/gerona\/52A.2.M117","article-title":"Heritability for Alzheimer's disease: the study of dementia in Swedish twins","volume":"52","author":"Gatz","year":"1997","journal-title":"J. Gerontol. A Biol. Sci."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0525","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1001\/archpsyc.63.2.168","article-title":"Role of genes and environments for explaining Alzheimer disease","volume":"63","author":"Gatz","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0530","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0197-4580(97)00012-2","article-title":"\u03b2-Amyloid (A\u03b2) deposition in the brains of aged orangutans","volume":"18","author":"Gearing","year":"1997","journal-title":"Neurobiol. Aging"},{"issue":"9","key":"10.1016\/bs.pbr.2022.10.004_bb0535","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/mp.2011.52","article-title":"APOE and Alzheimer disease: a major gene with semi-dominant inheritance","volume":"16","author":"Genin","year":"2011","journal-title":"Mol. Psychiatry"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0540","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13195-020-00740-0","article-title":"The association of APOE \u025b4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study","volume":"13","author":"Gharbi-Meliani","year":"2021","journal-title":"Alzheimer's Res. Ther."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0545","series-title":"Aging: The Biology of Senescence","author":"Gilbert","year":"2000"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0550","series-title":"Functional Neurobiology of Aging","first-page":"421","article-title":"Brain Aging in Strepsirhine Primates","author":"Gilissen","year":"2001"},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0555","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1242\/dmm.030205","article-title":"Neurodegenerative disease: models, mechanisms, and a new hope","volume":"10","author":"Gitler","year":"2017","journal-title":"Dis. Model Mech."},{"issue":"6183","key":"10.1016\/bs.pbr.2022.10.004_bb0560","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1126\/science.1250368","article-title":"Reconstructing the DNA methylation maps of the neandertal and the Denisovan","volume":"344","author":"Gokhman","year":"2014","journal-title":"Science"},{"issue":"2, Dementia","key":"10.1016\/bs.pbr.2022.10.004_bb0565","first-page":"435","article-title":"Lewy body dementias: Dementia with lewy bodies and Parkinson disease dementia","volume":"22","author":"Gomperts","year":"2016","journal-title":"Continuum (Minneap Minn)"},{"issue":"11","key":"10.1016\/bs.pbr.2022.10.004_bb0570","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1001\/jamaneurol.2016.3338","article-title":"Tau PET imaging in the Lewy body diseases","volume":"73","author":"Gomperts","year":"2016","journal-title":"JAMA Neurol."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0575","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1111\/j.1420-9101.2010.01976.x","article-title":"Large-brained mammals live longer","volume":"23","author":"Gonz\u00e1lez-Lagos","year":"2010","journal-title":"J. Evol. Biol."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0580","article-title":"Transcriptomic landscape, gene signatures and regulatory profile of aging in the human brain","volume":"1863","author":"Gonz\u00e1lez-Velasco","year":"2020","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0585","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1006\/nimg.2001.0786","article-title":"A voxel-based morphometric study of ageing in 465 normal adult human brains","volume":"14","author":"Good","year":"2001","journal-title":"Neuroimage"},{"issue":"22","key":"10.1016\/bs.pbr.2022.10.004_bb0590","doi-asserted-by":"crossref","first-page":"7466","DOI":"10.1093\/nar\/gkm756","article-title":"Changes in DNA repair during aging","volume":"35","author":"Gorbunova","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0595","series-title":"Synuclein and the Coelacanth","first-page":"181","article-title":"Monkey Brains \u2013 Evolution of the human brain and the vulnerability of the substantia nigra","author":"Gruschus","year":"2021"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0600","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jalz.2017.08.014","article-title":"Alzheimer's disease in humans and other animals: a consequence of postreproductive life span and longevity rather than aging","volume":"14","author":"Gunn-Moore","year":"2018","journal-title":"Alzheimers Dement."},{"issue":"MAY","key":"10.1016\/bs.pbr.2022.10.004_bb0605","doi-asserted-by":"crossref","first-page":"435","DOI":"10.3389\/fgene.2019.00435","article-title":"Regulation of mitochondrial biogenesis as a way for active longevity: interaction between the Nrf2 and PGC-1\u03b1 signaling pathways","volume":"10","author":"Gureev","year":"2019","journal-title":"Front. Genet."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0610","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1002\/ana.20694","article-title":"APOE \u025b4 is not associated with Alzheimer's disease in elderly Nigerians","volume":"59","author":"Gureje","year":"2006","journal-title":"Ann. Neurol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0615","series-title":"New Paths in Genetics, Nature","author":"Haldane","year":"1941"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0620","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0022-5193(64)90038-4","article-title":"The genetical evolution of social behaviour. I","volume":"7","author":"Hamilton","year":"1964","journal-title":"J. Theor. Biol."},{"issue":"8","key":"10.1016\/bs.pbr.2022.10.004_bb0625","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1001\/jamaneurol.2019.1424","article-title":"Association of amyloid and tau with cognition in preclinical Alzheimer disease: a longitudinal study","volume":"76","author":"Hanseeuw","year":"2019","journal-title":"JAMA Neurol."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0630","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1093\/geronj\/11.3.298","article-title":"Aging: a theory based on free radical and radiation chemistry","volume":"11","author":"Harman","year":"1956","journal-title":"J. Gerontol."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0635","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s10522-009-9234-2","article-title":"Origin and evolution of the free radical theory of aging: a brief personal history, 1954-2009","volume":"10","author":"Harman","year":"2009","journal-title":"Biogerontology"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0640","first-page":"69","article-title":"Primate infancies causes and consequences of varying care","volume":"22","author":"Hawkes","year":"2017","journal-title":"Cultural Nature of Attachment: Contextualizing Relationships and Development"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0645","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.146847","article-title":"Progressive brain changes in Parkinson's disease: a meta-analysis of structural magnetic resonance imaging studies","volume":"1740","author":"He","year":"2020","journal-title":"Brain Res."},{"issue":"19","key":"10.1016\/bs.pbr.2022.10.004_bb0650","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1212\/WNL.0b013e31828726f5","article-title":"Alzheimer disease in the United States (2010\u20132050) estimated using the 2010 census","volume":"80","author":"Hebert","year":"2013","journal-title":"Neurology"},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb1562","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1007\/s11357-011-9351-0","article-title":"Menopause occurs late in life in the captive chimpanzee (Pan troglodytes)","volume":"34","author":"Herndon","year":"2012","journal-title":"Age"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0655","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/(SICI)1096-9861(19990712)409:4<567::AID-CNE4>3.0.CO;2-J","article-title":"Brain weight throughout the life span of the chimpanzee","volume":"409","author":"Herndon","year":"1999","journal-title":"J. Comp. Neurol."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0660","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/S1474-4422(09)70062-6","article-title":"Neuroinflammation in Parkinson's disease: a target for neuroprotection?","volume":"8","author":"Hirsch","year":"2009","journal-title":"Lancet Neurol."},{"issue":"17","key":"10.1016\/bs.pbr.2022.10.004_bb0665","doi-asserted-by":"crossref","first-page":"6459","DOI":"10.1523\/JNEUROSCI.20-17-06459.2000","article-title":"Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+\/calmodulin-dependent protein kinase type IV\/Gr-Deficient mice","volume":"20","author":"Ho","year":"2000","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0670","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s00429-016-1213-1","article-title":"Vertex- and atlas-based comparisons in measures of cortical thickness, gyrification and white matter volume between humans and chimpanzees","volume":"222","author":"Hopkins","year":"2017","journal-title":"Brain Struct. Funct."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1564","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/jcbfm.1984.73","article-title":"Intercorrelations of glucose metabolic rates between brain regions: application to healthy males in a state of reduced sensory input","volume":"4","author":"Horwitz","year":"1984","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb0675","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/s41582-019-0244-7","article-title":"Ageing as a risk factor for neurodegenerative disease","volume":"15","author":"Hou","year":"2019","journal-title":"Nat. Rev. Neurol."},{"issue":"JAN","key":"10.1016\/bs.pbr.2022.10.004_bb0680","doi-asserted-by":"crossref","first-page":"703","DOI":"10.3389\/fgene.2018.00703","article-title":"Identification of Alzheimer's disease-related genes based on data integration method","volume":"10","author":"Hu","year":"2019","journal-title":"Front. Genet."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0685","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.pbb.2011.05.007","article-title":"Aged monkeys as a partial model for Parkinson's disease","volume":"99","author":"Hurley","year":"2011","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0690","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.neurobiolaging.2006.12.012","article-title":"Brain tissue volumes in the general elderly population. The Rotterdam Scan Study","volume":"29","author":"Ikram","year":"2008","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0695","unstructured":"IUCN (2022) The IUCN red list of threatened species. Available at: https:\/\/www.iucnredlist.org.\/ (Accessed: 14 October 2022)."},{"issue":"S3","key":"10.1016\/bs.pbr.2022.10.004_bb0700","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/ana.10483","article-title":"Oxidative stress in Parkinson's disease","volume":"53","author":"Jenner","year":"2003","journal-title":"Ann. Neurol."},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb0705","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.3174\/ajnr.A4447","article-title":"Longitudinal study of gray matter changes in Parkinson disease","volume":"36","author":"Jia","year":"2015","journal-title":"Am. J. Neuroradiol."},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb0710","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1111\/evo.14087","article-title":"Long life evolves in large-brained bird lineages","volume":"74","author":"Jim\u00e9nez-Ortega","year":"2020","journal-title":"Evolution"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0715","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2019.100947","article-title":"Revamping the evolutionary theories of aging","volume":"55","author":"Johnson","year":"2019","journal-title":"Ageing Res. Rev."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0720","doi-asserted-by":"crossref","first-page":"1000299","DOI":"10.1371\/journal.pbio.1000299","article-title":"The roles of PINK1 and parkin in Parkinson's disease","volume":"8","author":"Jones","year":"2010","journal-title":"PLoS Biol."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0725","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/NEN.0b013e3181922348","article-title":"Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease","volume":"68","author":"Julien","year":"2009","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1568","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1080\/02724634.1999.10011118","article-title":"The use of ancient DNA in paleontological studies","volume":"19","author":"Kelman","year":"1999","journal-title":"J. Vertebr. Paleontol."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0730","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.tins.2017.01.002","article-title":"Mitophagy and Alzheimer's disease: cellular and molecular mechanisms","volume":"40","author":"Kerr","year":"2017","journal-title":"Trends Neurosci."},{"issue":"1749","key":"10.1016\/bs.pbr.2022.10.004_bb0735","doi-asserted-by":"crossref","first-page":"4880","DOI":"10.1098\/rspb.2012.1751","article-title":"Increased longevity evolves from grandmothering","volume":"279","author":"Kim","year":"2012","journal-title":"Proc. R. Soc. B: Biol. Sci."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0740","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.neuroimage.2010.06.050","article-title":"Fractal dimension analysis of the cortical ribbon in mild Alzheimer's disease","volume":"53","author":"King","year":"2010","journal-title":"Neuroimage"},{"issue":"18","key":"10.1016\/bs.pbr.2022.10.004_bb0745","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.cub.2011.07.020","article-title":"On the programmed\/non-programmed nature of ageing within the life history","volume":"21","author":"Kirkwood","year":"2011","journal-title":"Curr. Biol."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0750","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a008888","article-title":"Genetics of Parkinson's disease","volume":"2","author":"Klein","year":"2012","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0755","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-24331-0","article-title":"Reconstructing the Neanderthal brain using computational anatomy","volume":"8","author":"Kochiyama","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0760","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/731526","article-title":"Structure and pathology of tau protein in Alzheimer disease","author":"Kolarova","year":"2012","journal-title":"Int. J. Alzheimer's Dis."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0765","series-title":"Parkinson's disease: etiology, neuropathology, and pathogenesis","author":"Kouli","year":"2018"},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0770","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1111\/acel.12510","article-title":"Can aging be programmed? A critical literature review","volume":"15","author":"Kowald","year":"2016","journal-title":"Aging Cell"},{"issue":"8","key":"10.1016\/bs.pbr.2022.10.004_bb1572","doi-asserted-by":"crossref","DOI":"10.1093\/molbev\/msac174","article-title":"TimeTree 5: an expanded resource for species divergence times","volume":"39","author":"Kumar","year":"2022","journal-title":"Mol. Biol. Evol."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0775","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.neurobiolaging.2013.08.036","article-title":"Cognitive and motor aging in female chimpanzees","volume":"35","author":"Lacreuse","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/bs.pbr.2022.10.004_bb1559","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.116637","article-title":"Cortical gyrification in relation to age and cognition in older adults","volume":"212","author":"Lamballais","year":"2020","journal-title":"NeuroImage"},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0780","doi-asserted-by":"crossref","first-page":"1002270","DOI":"10.1371\/journal.pmed.1002270","article-title":"APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: a genetic screening study of familial and sporadic cases","volume":"14","author":"Lanoisel\u00e9e","year":"2017","journal-title":"PLoS Med."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0785","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3389\/fnmol.2019.00010","article-title":"Combining gene transfer and nonhuman primates to better understand and treat Parkinson's disease","volume":"12","author":"Lasbleiz","year":"2019","journal-title":"Front. Mol. Neurosci."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0790","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/77046","article-title":"Gene-expression profile of the ageing brain in mice","volume":"25","author":"Lee","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0795","series-title":"Progress in Brain Research","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/B978-0-444-53860-4.00019-2","article-title":"Primate encephalization","author":"Lefebvre","year":"2012"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0800","doi-asserted-by":"crossref","DOI":"10.1016\/j.jas.2020.105237","article-title":"It's getting hot in here\u2014microcontextual study of a potential pit hearth at the Middle Paleolithic site of El Salt, Spain","volume":"123","author":"Leierer","year":"2020","journal-title":"J. Archaeol. Sci."},{"issue":"W1","key":"10.1016\/bs.pbr.2022.10.004_bb1578","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkab301","article-title":"Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation","volume":"49","author":"Letunic","year":"2021","journal-title":"Nucleic Acids Res."},{"issue":"Suppl. 4","key":"10.1016\/bs.pbr.2022.10.004_bb0805","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1067\/S0022-3476(03)00400-1","article-title":"Structural and functional maturation of the developing primate brain","volume":"143","author":"Levitt","year":"2003","journal-title":"J. Pediatr."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0810","first-page":"1755","article-title":"PARK genes link mitochondrial dysfunction and alpha-synuclein pathology in sporadic Parkinson's disease","volume":"9","author":"Li","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1569","doi-asserted-by":"crossref","DOI":"10.1093\/nsr\/nwaa292","article-title":"A cynomolgus monkey with naturally occurring Parkinson's disease","volume":"8","author":"Li","year":"2021","journal-title":"Natl. Sci. Rev."},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb1561","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1097\/WNR.0000000000001448","article-title":"Cortical complexity and gyrification patterns in Parkinson's disease","volume":"31","author":"Li","year":"2020","journal-title":"NeuroReport"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1570","doi-asserted-by":"crossref","DOI":"10.24272\/j.issn.2095-8137.2021.004","article-title":"Biological implications and limitations of a cynomolgus monkey with naturally occurring Parkinson's disease","volume":"42","author":"Li","year":"2021","journal-title":"Zool. Res."},{"issue":"DEC","key":"10.1016\/bs.pbr.2022.10.004_bb0815","first-page":"2964","article-title":"Commentary: clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease","volume":"6","author":"Liguori","year":"2015","journal-title":"Front. Neurol."},{"issue":"11","key":"10.1016\/bs.pbr.2022.10.004_bb0820","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1007\/s00415-018-9100-8","article-title":"Amyloid-\u03b2 and Parkinson's disease","volume":"266","author":"Lim","year":"2019","journal-title":"J. Neurol."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0825","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/j.neuron.2018.05.008","article-title":"APOE4 causes widespread molecular and cellular alterations associated with Alzheimer's disease phenotypes in human iPSC-derived brain cell types","volume":"98","author":"Lin","year":"2018","journal-title":"Neuron"},{"issue":"32","key":"10.1016\/bs.pbr.2022.10.004_bb0830","doi-asserted-by":"crossref","first-page":"14164","DOI":"10.1073\/pnas.1009485107","article-title":"Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease","volume":"107","author":"Lipinski","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0835","doi-asserted-by":"crossref","first-page":"31083","DOI":"10.1371\/journal.pone.0031083","article-title":"Cortical gyrification and sulcal spans in early stage Alzheimer's disease","volume":"7","author":"Liu","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0840","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1472-6831-14-65","article-title":"Tooth wear in aging people: an investigation of the prevalence and the influential factors of incisal\/occlusal tooth wear in northwest China","volume":"14","author":"Liu","year":"2014","journal-title":"BMC Oral Health"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0845","first-page":"453","article-title":"A voxel-based morphometric study of age- and sex-related changes in white matter volume in the normal aging brain","volume":"12","author":"Liu","year":"2016","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb0850","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1080\/15548627.2019.1615822","article-title":"Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys","volume":"15","author":"Livingston","year":"2019","journal-title":"Autophagy"},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb0855","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1371\/journal.pone.0003329","article-title":"Evolution of the aging brain transcriptome and synaptic regulation","volume":"3","author":"Loerch","year":"2008","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0860","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1002\/ajpa.24267","article-title":"Wild chimpanzee offspring exhibit adult-like foraging patterns around the age of weaning","volume":"175","author":"Lonsdorf","year":"2021","journal-title":"Am. J. Phys. Anthropol."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0865","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.cell.2013.05.039","article-title":"The hallmarks of aging","volume":"153","author":"L\u00f3pez-Ot\u00edn","year":"2013","journal-title":"Cell"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0870","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.molmed.2019.07.002","article-title":"Mitophagy and neuroprotection","volume":"26","author":"Lou","year":"2020","journal-title":"Trends Mol. Med."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb0875","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/BOR.0000000000000171","article-title":"Genetic contribution to osteoarthritis development: current state of evidence","volume":"27","author":"Loughlin","year":"2015","journal-title":"Curr. Opin. Rheumatol."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0880","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1046\/j.1471-4159.1999.0720771.x","article-title":"Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF","volume":"72","author":"Lovell","year":"1999","journal-title":"J. Neurochem."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1555","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1177\/0300985815612154","article-title":"Comparative pathology of aging great apes: bonobos, chimpanzees, gorillas, and orangutans","volume":"53","author":"Lowenstine","year":"2016","journal-title":"Vet. Pathol."},{"issue":"6994","key":"10.1016\/bs.pbr.2022.10.004_bb0885","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1038\/nature02661","article-title":"Gene regulation and DNA damage in the ageing human brain","volume":"429","author":"Lu","year":"2004","journal-title":"Nature"},{"issue":"3\u20134","key":"10.1016\/bs.pbr.2022.10.004_bb0890","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000453104","article-title":"Evolution of gyrification in carnivores","volume":"88","author":"Lyras","year":"2016","journal-title":"Brain Behav. Evol."},{"issue":"37","key":"10.1016\/bs.pbr.2022.10.004_bb0895","doi-asserted-by":"crossref","first-page":"58779","DOI":"10.18632\/oncotarget.9563","article-title":"MS4A6A genotypes are associated with the atrophy rates of Alzheimer's disease related brain structures","volume":"7","author":"Ma","year":"2016","journal-title":"Oncotarget"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0900","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1152\/physrev.1995.75.4.835","article-title":"Role of microtubule-associated proteins in the control of microtubule assembly","volume":"75","author":"Maccioni","year":"1995","journal-title":"Physiol. Rev."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb0905","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.tibs.2020.11.007","article-title":"Mitochondrial dysfunction and mitophagy in Parkinson's disease: from mechanism to therapy","volume":"46","author":"Malpartida","year":"2021","journal-title":"Trends Biochem. Sci."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0910","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s13167-010-0036-z","article-title":"Biomarkers for prediction and targeted prevention of Alzheimer's and Parkinson's diseases: evaluation of drug clinical efficacy","volume":"1","author":"Mandel","year":"2010","journal-title":"EPMA J."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0915","series-title":"Diet and Nutrition in Dementia and Cognitive Decline","author":"Martin","year":"2014"},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0920","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1111\/acel.12641","article-title":"Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers","volume":"16","author":"Mathews","year":"2017","journal-title":"Aging Cell"},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb0925","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a025130","article-title":"DNA damage, DNA repair, aging, and neurodegeneration","volume":"5","author":"Maynard","year":"2015","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0930","doi-asserted-by":"crossref","first-page":"17866","DOI":"10.1038\/s41598-019-54447-w","article-title":"A genomic predictor of lifespan in vertebrates","volume":"9","author":"Mayne","year":"2019","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb0935","doi-asserted-by":"crossref","first-page":"47760","DOI":"10.1371\/journal.pone.0047760","article-title":"The apolipoprotein E (APOE) gene appears functionally monomorphic in chimpanzees (pan troglodytes)","volume":"7","author":"McIntosh","year":"2012","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0940","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1136\/jnnp.2007.134163","article-title":"Dementia with Lewy bodies and Parkinson's disease with dementia: where two worlds collide","volume":"7","author":"McKeith","year":"2007","journal-title":"Pract. Neurol."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1567","doi-asserted-by":"crossref","first-page":"561","DOI":"10.18632\/aging.101413","article-title":"The evolution of CpG density and lifespan in conserved primate and mammalian promoters","volume":"10","author":"McLain","year":"2018","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/bs.pbr.2022.10.004_bb0945","series-title":"The Uniqueness of the Individual","first-page":"44","article-title":"An unsolved problem of biology","author":"Medawar","year":"1952"},{"issue":"6104","key":"10.1016\/bs.pbr.2022.10.004_bb0950","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1126\/science.1224344","article-title":"A high-coverage genome sequence from an archaic Denisovan individual","volume":"338","author":"Meyer","year":"2012","journal-title":"Science"},{"issue":"7595","key":"10.1016\/bs.pbr.2022.10.004_bb0955","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/nature17405","article-title":"Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins","volume":"531","author":"Meyer","year":"2016","journal-title":"Nature"},{"issue":"12\u201313","key":"10.1016\/bs.pbr.2022.10.004_bb0960","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1134\/S0006297918120106","article-title":"Can aging be programmed?","volume":"83","author":"Mitteldorf","year":"2018","journal-title":"Biochemistry (Mosc.)"},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb0965","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1136\/jnnp.2006.100123","article-title":"PINK1, a gene product of PARK6, accumulates in \u03b1-synucleinopathy brains","volume":"78","author":"Murakami","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0970","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s40478-018-0515-3","article-title":"White matter changes in Alzheimer's disease: a focus on myelin and oligodendrocytes","volume":"6","author":"Nasrabady","year":"2018","journal-title":"Acta Neuropathol. Commun."},{"issue":"52","key":"10.1016\/bs.pbr.2022.10.004_bb0975","doi-asserted-by":"crossref","first-page":"26669","DOI":"10.1073\/pnas.1903844116","article-title":"Postreproductive killer whale grandmothers improve the survival of their grandoffspring","volume":"116","author":"Nattrass","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb0980","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1111\/j.1365-2990.2011.01246.x","article-title":"Cerebral amyloid \u03b2(42) deposits and microvascular pathology in ageing baboons","volume":"38","author":"Ndung\u2019u","year":"2012","journal-title":"Neuropathol. Appl. Neurobiol."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb0985","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/NEN.0b013e3181919a48","article-title":"Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship","volume":"68","author":"Nelson","year":"2009","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb0990","series-title":"Trends in Pharmacological Sciences","article-title":"Molecular Neuropharmacology: A foundation for clinical neuroscience","author":"Nestler","year":"2009"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb0995","doi-asserted-by":"crossref","first-page":"139","DOI":"10.2174\/157015906776359577","article-title":"Neuronal cell death in Alzheimers disease and a neuroprotective factor, humanin","volume":"4","author":"Niikura","year":"2006","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1000","article-title":"Hippocampal volume across age: nomograms derived from over 19,700 people in UK Biobank","volume":"23","author":"Nobis","year":"2019","journal-title":"NeuroImage"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1005","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1093\/icb\/42.4.743","article-title":"Understanding vertebrate brain evolution","volume":"42","author":"Northcutt","year":"2002","journal-title":"Integr. Comp. Biol."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13195-016-0208-8","article-title":"The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer's disease","volume":"8","author":"\u00d6hrfelt","year":"2016","journal-title":"Alzheimer's Res. Ther."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1015","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.brainres.2009.12.005","article-title":"Alzheimer-type tau pathology in advanced aged nonhuman primate brains harboring substantial amyloid deposition","volume":"1315","author":"Oikawa","year":"2010","journal-title":"Brain Res."},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb1020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11910-018-0874-y","article-title":"The genetics of dementia with Lewy bodies: current understanding and future directions","volume":"18","author":"Orme","year":"2018","journal-title":"Curr. Neurol. Neurosci. Rep."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1025","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1002\/mds.28387","article-title":"From iPS cells to rodents and nonhuman primates: filling gaps in modeling Parkinson's disease","volume":"36","author":"Outeiro","year":"2021","journal-title":"Mov. Disord."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb1030","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1002\/prp2.795","article-title":"Immunomodulation induced by central nervous system-related peptides as a therapeutic strategy for neurodegenerative disorders","volume":"9","author":"Palumbo","year":"2021","journal-title":"Pharmacol. Res. Perspect."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1035","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/mds.20663","article-title":"Presence of an APOE4 allele results in significantly earlier onset of Parkinson's disease and a higher risk with dementia","volume":"21","author":"Pankratz","year":"2006","journal-title":"Mov. Disord."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1040","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/nrg753","article-title":"Mechanisms of ageing: public or private?","volume":"3","author":"Partridge","year":"2002","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1556","doi-asserted-by":"crossref","first-page":"4318","DOI":"10.1002\/cne.23428","article-title":"Alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (Gorilla gorilla gorilla)","volume":"521","author":"Perez","year":"2013","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1045","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.neurobiolaging.2015.12.017","article-title":"Early Alzheimer's disease-type pathology in the frontal cortex of wild mountain gorillas (Gorilla beringei beringei)","volume":"39","author":"Perez","year":"2016","journal-title":"Neurobiol. Aging"},{"issue":"964","key":"10.1016\/bs.pbr.2022.10.004_bb1050","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1136\/pgmj.2005.036665","article-title":"Ageing and the brain","volume":"82","author":"Peters","year":"2006","journal-title":"Postgrad. Med. J."},{"issue":"9","key":"10.1016\/bs.pbr.2022.10.004_bb1055","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1002\/ajp.22281","article-title":"Why primate models matter","volume":"76","author":"Phillips","year":"2014","journal-title":"Am. J. Primatol."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1060","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.exger.2006.09.013","article-title":"Aging affects executive functions and memory in mouse lemur primates","volume":"42","author":"Picq","year":"2007","journal-title":"Exp. Gerontol."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1065","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.neurobiolaging.2010.09.009","article-title":"Age-related cerebral atrophy in nonhuman primates predicts cognitive impairments","volume":"33","author":"Picq","year":"2012","journal-title":"Neurobiol. Aging"},{"issue":"15","key":"10.1016\/bs.pbr.2022.10.004_bb1070","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1212\/WNL.0000000000002001","article-title":"Longitudinal study of normal cognition in Parkinson disease","volume":"85","author":"Pigott","year":"2015","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1075","first-page":"1423","article-title":"Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease","volume":"138","author":"Podlisny","year":"1991","journal-title":"Am. J. Pathol."},{"issue":"15","key":"10.1016\/bs.pbr.2022.10.004_bb1080","doi-asserted-by":"crossref","first-page":"8426","DOI":"10.1073\/pnas.96.15.8426","article-title":"Protein preservation and DNA retrieval from ancient tissues","volume":"96","author":"Poinar","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"7603","key":"10.1016\/bs.pbr.2022.10.004_bb1085","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/nature17654","article-title":"Metabolic acceleration and the evolution of human brain size and life history","volume":"533","author":"Pontzer","year":"2016","journal-title":"Nature"},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1090","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/1531-8249(199903)45:3<358::AID-ANA12>3.0.CO;2-X","article-title":"Tangles and plaques in nondemented aging and \u2018preclinical\u2019 Alzheimer's disease","volume":"45","author":"Price","year":"1999","journal-title":"Ann. Neurol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1095","series-title":"World Alzheimer Report 2014 - Dementia and risk reduction: an analysis of protective and modifiable factors","first-page":"1","author":"Prince","year":"2014"},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1100","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/nrneurol.2015.10","article-title":"White matter hyperintensities, cognitive impairment and dementia: an update","volume":"11","author":"Prins","year":"2015","journal-title":"Nat. Rev. Neurol."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1105","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.neurobiolaging.2013.08.002","article-title":"Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood","volume":"35","author":"Proitsi","year":"2014","journal-title":"Neurobiol. Aging"},{"issue":"AUG","key":"10.1016\/bs.pbr.2022.10.004_bb1110","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3389\/fnagi.2018.00235","article-title":"Gray matter volume and cognitive performance during normal aging. A voxel-based morphometry study","volume":"10","author":"Ramano\u00ebl","year":"2018","journal-title":"Front. Aging Neurosci."},{"issue":"11","key":"10.1016\/bs.pbr.2022.10.004_bb1115","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1093\/cercor\/bhi044","article-title":"Regional brain changes in aging healthy adults: general trends, individual differences and modifiers","volume":"15","author":"Raz","year":"2005","journal-title":"Cereb. Cortex"},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb1120","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s10329-019-00732-1","article-title":"Social relationships and caregiving behavior between recently orphaned chimpanzee siblings","volume":"60","author":"Reddy","year":"2019","journal-title":"Primates"},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb1125","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1016\/j.bbamcr.2016.09.012","article-title":"Activation of apoptosis signalling pathways by reactive oxygen species","volume":"1863","author":"Redza-Dutordoir","year":"2016","journal-title":"Biochim. Biophys. Acta\u2014Mol. Cell Res."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1130","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.nbd.2018.11.012","article-title":"The role of monogenic genes in idiopathic Parkinson's disease","volume":"124","author":"Reed","year":"2019","journal-title":"Neurobiol. Dis."},{"issue":"7327","key":"10.1016\/bs.pbr.2022.10.004_bb1135","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1038\/nature09710","article-title":"Genetic history of an archaic hominin group from Denisova cave in Siberia","volume":"468","author":"Reich","year":"2010","journal-title":"Nature"},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1140","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1212\/WNL.0b013e318245d295","article-title":"\u03b2-Amyloid burden in healthy aging: regional distribution and cognitive consequences","volume":"78","author":"Rodrigue","year":"2012","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1145","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/cne.21744","article-title":"Tauopathy with paired helical filaments in an aged chimpanzee","volume":"509","author":"Rosen","year":"2008","journal-title":"J. Comp. Neurol."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb1150","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.tics.2005.03.005","article-title":"Evolution of the brain and intelligence","volume":"9","author":"Roth","year":"2005","journal-title":"Trends Cogn. Sci."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-99289-7","article-title":"Possible vertebral brucellosis infection in a Neanderthal","volume":"11","author":"Rothschild","year":"2021","journal-title":"Sci. Rep."},{"issue":"6629","key":"10.1016\/bs.pbr.2022.10.004_bb1160","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/387173a0","article-title":"Body mass and encephalization in Pleistocene Homo","volume":"387","author":"Ruff","year":"1997","journal-title":"Nature"},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb1580","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.2174\/1871527313666140917122739","article-title":"The impact of dementia development concurrent with Parkinson's disease: a new perspective","volume":"13","author":"Russell","year":"2014","journal-title":"CNS Neurol. Disord. Drug Targets"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12916-019-1299-4","article-title":"ApoE4: an emerging therapeutic target for Alzheimer's disease","volume":"17","author":"Safieh","year":"2019","journal-title":"BMC Med."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1170","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3390\/life11030229","article-title":"The cellular senescence stress response in post-mitotic brain cells: cell survival at the expense of tissue degeneration","volume":"11","author":"Sah","year":"2021","journal-title":"Life"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1175","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/j.neuroimage.2008.10.030","article-title":"Regional white matter volume differences in nondemented aging and Alzheimer's disease","volume":"44","author":"Salat","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/bs.pbr.2022.10.004_bb1180","doi-asserted-by":"crossref","first-page":"166","DOI":"10.18632\/aging.100444","article-title":"Inflammaging: disturbed interplay between autophagy and inflammasomes","author":"Salminen","year":"2012","journal-title":"Aging"},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1185","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s10522-017-9732-6","article-title":"Exercise and bone health across the lifespan","volume":"18","author":"Santos","year":"2017","journal-title":"Biogerontology"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1190","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1749-6632.2000.tb05567.x","article-title":"Alzheimer's disease and some speculations about the evolution of its modifiers","volume":"924","author":"Sapolsky","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1565","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1109\/TMI.2007.903576","article-title":"A surface-based approach to quantify local cortical gyrification","volume":"27","author":"Schaer","year":"2008","journal-title":"IEEE Trans. Med. Imaging"},{"key":"10.1016\/bs.pbr.2022.10.004_bb1195","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.cma.2019.04.028","article-title":"The interplay of biochemical and biomechanical degeneration in Alzheimer's disease","volume":"352","author":"Sch\u00e4fer","year":"2019","journal-title":"Comput. Methods Appl. Mech. Eng."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1200","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/8756-3282(95)00370-3","article-title":"Aging and matrix microdamage accumulation in human compact bone","volume":"17","author":"Schaffler","year":"1995","journal-title":"Bone"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1205","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/s41418-020-00706-7","article-title":"Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities","volume":"28","author":"Schmidt","year":"2021","journal-title":"Cell Death Differ."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1210","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/jnen\/59.1.39","article-title":"Filamentous tau pathology in nerve cells, astrocytes, and oligodendrocytes of aged baboons","volume":"59","author":"Schultz","year":"2000","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1215","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/npjamd.2016.14","article-title":"Gene expression signatures of human cell and tissue longevity","volume":"2","author":"Seim","year":"2016","journal-title":"NPJ Aging Mech. Dis."},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb1220","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/j.neurobiolaging.2005.07.019","article-title":"Hippocampal volume is preserved and fails to predict recognition memory impairment in aged rhesus monkeys (Macaca mulatta)","volume":"27","author":"Shamy","year":"2006","journal-title":"Neurobiol. Aging"},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb1225","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1093\/cercor\/bhq210","article-title":"Volumetric correlates of spatiotemporal working and recognition memory impairment in aged rhesus monkeys","volume":"21","author":"Shamy","year":"2011","journal-title":"Cereb. Cortex"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1230","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jfma.2015.08.004","article-title":"A systematic review of familial Alzheimer's disease: Differences in presentation of clinical features among three mutated genes and potential ethnic differences","volume":"115","author":"Shea","year":"2016","journal-title":"J. Formos. Med. Assoc."},{"issue":"32","key":"10.1016\/bs.pbr.2022.10.004_bb1235","doi-asserted-by":"crossref","first-page":"13029","DOI":"10.1073\/pnas.1016709108","article-title":"Aging of the cerebral cortex differs between humans and chimpanzees","volume":"108","author":"Sherwood","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb1240","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1097\/GME.0000000000000341","article-title":"Anthropology and the study of menopause: Evolutionary, developmental, and comparative perspectives","volume":"21","author":"Sievert","year":"2014","journal-title":"Menopause"},{"issue":"27","key":"10.1016\/bs.pbr.2022.10.004_bb1245","doi-asserted-by":"crossref","first-page":"10987","DOI":"10.1073\/pnas.0812140106","article-title":"Virtual endocast of Ignacius graybullianus (Paromomyidae, Primates) and brain evolution in early primates","volume":"106","author":"Silcox","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"23","key":"10.1016\/bs.pbr.2022.10.004_bb1250","doi-asserted-by":"crossref","first-page":"6380","DOI":"10.1073\/pnas.1524306113","article-title":"Ancient DNA and human history","volume":"113","author":"Slatkin","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"Pt 11","key":"10.1016\/bs.pbr.2022.10.004_bb1255","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1093\/brain\/awl203","article-title":"APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy","volume":"129","author":"Sleegers","year":"2006","journal-title":"Brain"},{"issue":"7722","key":"10.1016\/bs.pbr.2022.10.004_bb1260","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/s41586-018-0448-9","article-title":"Parkin and PINK1 mitigate STING-induced inflammation","volume":"561","author":"Sliter","year":"2018","journal-title":"Nature"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1265","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/ajpa.1330860206","article-title":"Dental development and the evolution of life history in Hominidae","volume":"86","author":"Smith","year":"1991","journal-title":"Am. J. Phys. Anthropol."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb1270","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1007\/s12035-020-02248-y","article-title":"Aging-dependent mitophagy dysfunction in Alzheimer's disease","volume":"58","author":"Song","year":"2021","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1275","series-title":"Diseases of the Nervous System","article-title":"Aging, Dementia, and Alzheimer Disease\u2019","author":"Sontheimer","year":"2015"},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1280","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1086\/420539","article-title":"Evolution in health and disease: work in progress","volume":"76","author":"Stearns","year":"2001","journal-title":"Q. Rev. Biol."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1285","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a009399","article-title":"\u03b1-Synuclein in Parkinson's disease","volume":"2","author":"Stefanis","year":"2012","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"16","key":"10.1016\/bs.pbr.2022.10.004_bb1290","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1016\/j.jmb.2017.06.019","article-title":"Transcriptional signatures of aging","volume":"429","author":"Stegeman","year":"2017","journal-title":"J. Mol. Biol."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1295","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/imm.12922","article-title":"Inflammation in CNS neurodegenerative diseases","volume":"154","author":"Stephenson","year":"2018","journal-title":"Immunology"},{"issue":"13","key":"10.1016\/bs.pbr.2022.10.004_bb1300","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.cub.2011.05.001","article-title":"Evolutionary conservation of the basal ganglia as a common vertebrate mechanism for action selection","volume":"21","author":"Stephenson-Jones","year":"2011","journal-title":"Curr. Biol."},{"issue":"7 NOV","key":"10.1016\/bs.pbr.2022.10.004_bb1305","article-title":"Proposed evolutionary changes in the role of myelin","volume":"7","author":"Stiefel","year":"2013","journal-title":"Front. Neurosci."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1310","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s11065-010-9148-4","article-title":"The basics of brain development","volume":"20","author":"Stiles","year":"2010","journal-title":"Neuropsychol. Rev."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1315","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2021.734173","article-title":"The rhesus macaque as a translational model for neurodegeneration and Alzheimer's disease","volume":"13","author":"Stonebarger","year":"2021","journal-title":"Front. Aging Neurosci."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1320","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1086\/401979","article-title":"Pathology and the posture of Neanderthal man","volume":"32","author":"Straus","year":"1957","journal-title":"Q. Rev. Biol."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1330","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1001\/archneur.62.2.281","article-title":"Structural brain changes in Parkinson disease with dementia: a voxel-based morphometry study","volume":"62","author":"Summerfield","year":"2005","journal-title":"Arch. Neurol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1335","doi-asserted-by":"crossref","DOI":"10.3389\/fnhum.2020.602360","article-title":"Exploiting common aspects of obesity and Alzheimer's disease","volume":"14","author":"Tabassum","year":"2020","journal-title":"Front. Hum. Neurosci."},{"issue":"Database issue","key":"10.1016\/bs.pbr.2022.10.004_bb1579","doi-asserted-by":"crossref","first-page":"D1083","DOI":"10.1093\/nar\/gkx1042","article-title":"Human Ageing Genomic Resources: new and updated databases","volume":"46","author":"Tacutu","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1340","doi-asserted-by":"crossref","first-page":"87","DOI":"10.14348\/molcells.2016.2318","article-title":"Sirt1 and the mitochondria","volume":"39","author":"Tang","year":"2016","journal-title":"Mol. Cells"},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb1345","doi-asserted-by":"crossref","first-page":"6296","DOI":"10.1101\/cshperspect.a006296","article-title":"The genetics of Alzheimer disease","volume":"2","author":"Tanzi","year":"2012","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"13","key":"10.1016\/bs.pbr.2022.10.004_bb1350","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1016\/j.cell.2022.05.017","article-title":"Cholesterol and matrisome pathways dysregulated in astrocytes and microglia","volume":"185","author":"Tcw","year":"2022","journal-title":"Cell"},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb1355","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1212\/WNL.58.12.1791","article-title":"Phases of A\u03b2-deposition in the human brain and its relevance for the development of AD","volume":"58","author":"Thal","year":"2002","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1360","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.nrleng.2012.07.002","article-title":"Does Alzheimer's disease exist in all primates? Alzheimer pathology in non-human primates and its pathophysiological implications (I)","volume":"27","author":"Toledano","year":"2012","journal-title":"Neurolog\u00eda (English Edition)"},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb1365","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S1474-4422(21)00030-2","article-title":"Challenges in the diagnosis of Parkinson's disease","volume":"20","author":"Tolosa","year":"2021","journal-title":"Lancet Neurol."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1370","first-page":"1","article-title":"Genetic predispositions of Parkinson's disease revealed in patient-derived brain cells","volume":"6","author":"Tran","year":"2020","journal-title":"NPJ Parkinson's Dis."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1375","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1073\/pnas.1018700108","article-title":"Late Pleistocene adult mortality patterns and modern human establishment","volume":"108","author":"Trinkaus","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1380","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2174\/1874609812666191014111422","article-title":"The mechanism of programmed aging: the way to create a real remedy for senescence","volume":"13","author":"Trubitsyn","year":"2020","journal-title":"Curr. Aging Sci."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1385","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s40478-016-0385-5","article-title":"Tau pathology in aged cynomolgus monkeys is progressive supranuclear palsy\/corticobasal degeneration- but not Alzheimer disease-like -Ultrastructural mapping of tau by EDX","volume":"4","author":"Uchihara","year":"2016","journal-title":"Acta Neuropathol. Commun."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1390","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1080\/17460441.2017.1271320","article-title":"Non human primate models for Alzheimer's disease-related research and drug discovery","volume":"12","author":"Van Dam","year":"2017","journal-title":"Expert Opin. Drug Discovery"},{"issue":"7849","key":"10.1016\/bs.pbr.2022.10.004_bb1395","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/s41586-021-03224-9","article-title":"Million-year-old DNA sheds light on the genomic history of mammoths","volume":"591","author":"van der Valk","year":"2021","journal-title":"Nature"},{"issue":"7501","key":"10.1016\/bs.pbr.2022.10.004_bb1400","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/nature13193","article-title":"The role of senescent cells in ageing","volume":"509","author":"Van Deursen","year":"2014","journal-title":"Nature"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1405","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/ng0594-74","article-title":"Apolipoprotein E4 allele in a population\u2013based study of early\u2013onset Alzheimer's disease","volume":"7","author":"Van Duijn","year":"1994","journal-title":"Nat. Genet."},{"issue":"7","key":"10.1016\/bs.pbr.2022.10.004_bb1410","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179497","article-title":"Effect of APOE \u025b4 allele on survival and fertility in an adverse environment","volume":"12","author":"Van Exel","year":"2017","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/bs.pbr.2022.10.004_bb1415","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.tins.2010.09.004","article-title":"\u03b1-Synuclein and dopamine at the crossroads of Parkinson's disease","volume":"33","author":"Venda","year":"2010","journal-title":"Trends Neurosci."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1563","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0096424","article-title":"Neandertal demise: an archaeological analysis of the modern human superiority complex","volume":"9","author":"Villa","year":"2014","journal-title":"PLoS ONE"},{"issue":"8","key":"10.1016\/bs.pbr.2022.10.004_bb1420","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1089\/ars.2012.5111","article-title":"The free radical theory of aging revisited: the cell signaling disruption theory of aging","volume":"19","author":"Vi\u00f1a","year":"2013","journal-title":"Antioxid. Redox Signal."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1425","first-page":"14","article-title":"Age estimation in archaeological skeletal remains: evaluation of four non-destructive age calculation methods","volume":"29","author":"Vodanovi\u0107","year":"2011","journal-title":"J. Forensic Odonto-Stomatol."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1430","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s12035-012-8280-y","article-title":"The Lewy body in Parkinson's disease and related neurodegenerative disorders","volume":"47","author":"Wakabayashi","year":"2013","journal-title":"Mol. Neurobiol."},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1435","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1095\/biolreprod.108.068536","article-title":"Menopause in nonhuman primates?","volume":"79","author":"Walker","year":"2008","journal-title":"Biol. Reprod."},{"issue":"6","key":"10.1016\/bs.pbr.2022.10.004_bb1440","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.molmed.2017.04.001","article-title":"The exceptional vulnerability of humans to Alzheimer's disease","volume":"23","author":"Walker","year":"2017","journal-title":"Trends Mol. Med."},{"issue":"5","key":"10.1016\/bs.pbr.2022.10.004_bb1445","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/jnc.14698","article-title":"Clinical and neuropathological differences between Parkinson's disease, Parkinson's disease dementia and dementia with Lewy bodies\u2014current issues and future directions","volume":"150","author":"Walker","year":"2019","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1450","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s40035-015-0027-z","article-title":"Voxel-based meta-analysis of grey matter changes in Alzheimer's disease","volume":"4","author":"Wang","year":"2015","journal-title":"Transl. Neurodegener."},{"issue":"10100","key":"10.1016\/bs.pbr.2022.10.004_bb1455","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/S0140-6736(17)31833-0","article-title":"Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"390","author":"Wang","year":"2017","journal-title":"Lancet"},{"issue":"7762","key":"10.1016\/bs.pbr.2022.10.004_bb1460","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/d41586-019-01986-x","article-title":"Move over, DNA: ancient proteins are starting to reveal humanity's history","volume":"570","author":"Warren","year":"2019","journal-title":"Nature"},{"key":"10.1016\/bs.pbr.2022.10.004_bb1465","series-title":"Essays upon heredity and kindred biological problems","article-title":"Essays upon heredity and kindred biological problems","author":"Weismann","year":"1891"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1560","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.bandc.2009.10.009","article-title":"The development of gyrification in childhood and adolescence","volume":"72","author":"White","year":"2010","journal-title":"Brain Cogn."},{"issue":"9","key":"10.1016\/bs.pbr.2022.10.004_bb1470","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1038\/s41588-021-00921-z","article-title":"A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease","volume":"53","author":"Wightman","year":"2021","journal-title":"Nat. Genet."},{"issue":"4","key":"10.1016\/bs.pbr.2022.10.004_bb1475","doi-asserted-by":"crossref","first-page":"398","DOI":"10.2307\/2406060","article-title":"Pleiotropy, natural selection, and the evolution of senescence","volume":"11","author":"Williams","year":"1957","journal-title":"Evolution"},{"issue":"11","key":"10.1016\/bs.pbr.2022.10.004_bb1480","doi-asserted-by":"crossref","first-page":"631","DOI":"10.2307\/1296775","article-title":"Group selection and its significance for ecology","volume":"23","author":"Wilson","year":"1973","journal-title":"Bioscience"},{"key":"10.1016\/bs.pbr.2022.10.004_bb1485","author":"World Health Organization"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1490","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40478-020-00907-8","article-title":"Meta-analysis of human prefrontal cortex reveals activation of GFAP and decline of synaptic transmission in the aging brain","volume":"8","author":"Wruck","year":"2020","journal-title":"Acta Neuropathol. Commun."},{"issue":"8","key":"10.1016\/bs.pbr.2022.10.004_bb1571","doi-asserted-by":"crossref","DOI":"10.1007\/s12264-021-00708-6","article-title":"Naturally occurring Parkinson's disease raises the need for nonhuman primates in neurodegenerative diseases research","volume":"37","author":"Yao","year":"2021","journal-title":"Neurosci. Bull."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1495","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jneumeth.2008.08.027","article-title":"Striatal volume differences between non-human and human primates","volume":"176","author":"Yin","year":"2009","journal-title":"J. Neurosci. Methods"},{"issue":"1","key":"10.1016\/bs.pbr.2022.10.004_bb1500","doi-asserted-by":"crossref","first-page":"35","DOI":"10.5483\/BMBRep.2020.53.1.274","article-title":"Emerging perspectives on mitochondrial dysfunction and inflammation in Alzheimer's disease","volume":"53","author":"Yoo","year":"2020","journal-title":"BMB Rep."},{"issue":"6454","key":"10.1016\/bs.pbr.2022.10.004_bb1505","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaw9855","article-title":"Mitochondria\u2014striking a balance between host and endosymbiont","volume":"365","author":"Youle","year":"2019","journal-title":"Science"},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1510","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1177\/0300985815623997","article-title":"Pathology of the aging brain in domestic and laboratory animals, and animal models of human neurodegenerative diseases","volume":"53","author":"Youssef","year":"2016","journal-title":"Vet. Pathol."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1515","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/ana.10795","article-title":"The new mutation, E46K, of \u03b1-synuclein causes Parkinson and Lewy body dementia","volume":"55","author":"Zarranz","year":"2004","journal-title":"Ann. Neurol."},{"issue":"10","key":"10.1016\/bs.pbr.2022.10.004_bb1520","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/gerona\/55.10.B473","article-title":"Motor slowing and Parkinsonian signs in aging rhesus monkeys mirror human aging","volume":"55","author":"Zhang","year":"2000","journal-title":"J. Gerontol. A Biol. Sci."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1525","series-title":"The model of aging acceleration network reveals the correlation of Alzheimer's disease and aging at system level","author":"Zhou","year":"2019"},{"issue":"3","key":"10.1016\/bs.pbr.2022.10.004_bb1530","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2174\/1871528113666140522112003","article-title":"Inflammaging in skin and other tissues\u2014the roles of complement system and macrophage","volume":"13","author":"Zhuang","year":"2014","journal-title":"Inflamm. Allergy Drug Targets"},{"key":"10.1016\/bs.pbr.2022.10.004_bb1535","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.575645","article-title":"Updating the free radical theory of aging","volume":"8","author":"Ziada","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"issue":"24","key":"10.1016\/bs.pbr.2022.10.004_bb1540","doi-asserted-by":"crossref","first-page":"7466","DOI":"10.1073\/pnas.1505071112","article-title":"Body composition in Pan paniscus compared with Homo sapiens has implications for changes during human evolution","volume":"112","author":"Zihlman","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1545","first-page":"35","article-title":"Personal ornaments and symbolism among the Neanderthals","volume":"16","author":"Zilh\u00e3o","year":"2012","journal-title":"Dev. Quat. Sci."},{"issue":"2","key":"10.1016\/bs.pbr.2022.10.004_bb1558","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/BF00304699","article-title":"Gyrification in the cerebral cortex of primates","volume":"179","author":"Zilles","year":"1988","journal-title":"Anat. Embryol."},{"key":"10.1016\/bs.pbr.2022.10.004_bb1550","doi-asserted-by":"crossref","first-page":"962","DOI":"10.3389\/fneur.2019.00962","article-title":"Editorial: radiopharmaceuticals, imaging techniques and clinical applications in neurodegenerative diseases","volume":"10","author":"Zuo","year":"2019","journal-title":"Front. Neurol."}],"container-title":["Progress in Brain Research","From Fossils to Mind"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0079612322001893?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0079612322001893?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T15:33:59Z","timestamp":1677857639000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0079612322001893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"ISBN":["9780323991070"],"references-count":332,"URL":"https:\/\/doi.org\/10.1016\/bs.pbr.2022.10.004","relation":{},"ISSN":["0079-6123"],"issn-type":[{"value":"0079-6123","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]}}}