{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:03:25Z","timestamp":1791486205510,"version":"4.3.4"},"reference-count":91,"publisher":"Elsevier","isbn-type":[{"value":"9780128177402","type":"print"}],"license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.1016\/bs.pmbts.2019.03.011","type":"book-chapter","created":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T04:58:16Z","timestamp":1554958696000},"page":"95-111","source":"Crossref","is-referenced-by-count":57,"title":["Use of fucoidan to treat renal diseases: A review of 15 years of clinic studies"],"prefix":"10.1016","author":[{"given":"Jing","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihua","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanbin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/bs.pmbts.2019.03.011_bb0010","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1007\/s11434-013-5745-y","article-title":"Bioactivity and constituents of several common seaweeds","volume":"58","author":"Zhang","year":"2013","journal-title":"Chin Sci Bull"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0015","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1186\/s12906-016-1332-5","article-title":"Enhancement of Calibrachoa growth, secondary metabolites and bioactivity using seaweed extracts","volume":"16","author":"Elansary","year":"2016","journal-title":"BMC Complement Altern Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0020","series-title":"Chinese Pharmaceutics of Maine Lakes and Marshes","first-page":"321","article-title":"Laminaria japonica Aresch","author":"Jia","year":"1996"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0025","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/ptr.1623","article-title":"Fucoidan inhibits the development of proteinuria in active Heymann nephritis","volume":"19","author":"Zhang","year":"2005","journal-title":"Phytother Res"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0030","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jep.2017.12.013","article-title":"Zhen-wu-tang ameliorates adenine-induced chronic renal failure in rats: regulation of the canonical Wnt4\/beta-catenin signaling in the kidneys","volume":"219","author":"La","year":"2018","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0035","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/nrneph.2015.85","article-title":"Early chronic kidney disease: diagnosis, management and models of care","volume":"11","author":"Wouters","year":"2015","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0040","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1538\/expanim.17-0131","article-title":"STF-083010, an inhibitor of XBP1 splicing, attenuates acute renal failure in rats by suppressing endoplasmic reticulum stress-induced apoptosis and inflammation","volume":"67","author":"Liu","year":"2018","journal-title":"Exp Anim"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.semcdb.2018.05.024","article-title":"Evolution, kidney development, and chronic kidney disease","author":"Chevalier","year":"2018","journal-title":"Semin Cell Dev Biol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0050","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.dsx.2018.01.002","article-title":"Glycated albumin in chronic kidney disease: pathophysiologic connections","volume":"12","author":"Raghav","year":"2018","journal-title":"Diabetes Metab Syndr Clin Res Rev"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0055","article-title":"262 cases study on effect of Haikunshenxi capsules in treatment of patients with CKD 2\u20133 stage","author":"Li","year":"2010"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0060","first-page":"151","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure","volume":"15","author":"Shi","year":"2013","journal-title":"Chin Pract Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0065","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.foodchem.2017.11.083","article-title":"Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield","volume":"245","author":"Zhao","year":"2018","journal-title":"Food Chem"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0070","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.carbpol.2013.08.033","article-title":"Purification of a fucoidan from kelp polysaccharide and its inhibitory kinetics for tyrosinase","volume":"99","author":"Yu","year":"2014","journal-title":"Carbohydr Polym"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0075","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ijbiomac.2007.10.003","article-title":"Antioxidant activity of sulfated polysaccharide fractions extracted from Laminaria japonica","volume":"42","author":"Wang","year":"2008","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0080","doi-asserted-by":"crossref","first-page":"7656","DOI":"10.1074\/jbc.274.12.7656","article-title":"Structure and anticoagulant activity of sulfated fucans\u2014comparison between the regular, repetitive, and linear fucans from echinoderms with the more heterogeneous and branched polymers from brown algae","volume":"274","author":"Pereira","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0085","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.ijbiomac.2010.05.010","article-title":"Structural studies on a novel fucogalactan sulfate extracted from the brown seaweed Laminaria japonica","volume":"47","author":"Wang","year":"2010","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0090","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.3390\/md10102138","article-title":"Structural analysis of a Heteropolysaccharide from Saccharina japonica by electrospray mass spectrometry in tandem with collision-induced dissociation tandem mass spectrometry (ESI-CID-MS\/MS)","volume":"10","author":"Jin","year":"2012","journal-title":"Mar Drugs"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0095","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1055\/s-2003-40634","article-title":"Effects of fucoidan on chronic renal failure in rats","volume":"69","author":"Zhang","year":"2003","journal-title":"Planta Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0100","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s10811-005-9003-9","article-title":"Antioxidant activity of different molecular weight sulfated polysaccharides from Ulva pertusa Kjellm (Chlorophyta)","volume":"17","author":"Qi","year":"2005","journal-title":"J Appl Phycol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0105","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1016\/j.bmcl.2006.01.076","article-title":"In vitro antioxidant activity of acetylated and benzoylated derivatives of polysaccharide extracted from Ulva pertusa (Chlorophyta)","volume":"16","author":"Qi","year":"2006","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0110","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/j.lfs.2006.06.014","article-title":"Renal peroxidative changes mediated by oxalate: the protective role of fucoidan","volume":"79","author":"Veena","year":"2006","journal-title":"Life Sci"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0115","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00240-002-0286-x","article-title":"Oxalate and calcium oxalate mediated free radical toxicity in renal epithelial cells: effect of antioxidants","volume":"31","author":"Thamilselvan","year":"2003","journal-title":"Urol Res"},{"issue":"5","key":"10.1016\/bs.pmbts.2019.03.011_bb0120","first-page":"386","article-title":"Effect of fucoidan on the human renal interstitial fibroblast","volume":"12","author":"Shang","year":"2011","journal-title":"Chin J Integr Tradit West Nephrol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0125","first-page":"100","article-title":"Effect of fucoidan on renal interstitial fibrosis in adenine-induced chronic renal failure in rats","volume":"2","author":"Liu","year":"2008","journal-title":"Chin J Integr Tradit West Nephrol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0130","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ijbiomac.2016.11.051","article-title":"Renoprotective effect of low-molecular-weight sulfated polysaccharide from the seaweed Laminaria japonica on glycerol-induced acute kidney injury in rats","volume":"95","author":"Li","year":"2017","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0135","first-page":"13","article-title":"Oligo-fucoidan prevents renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway","volume":"7","author":"Chen","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0140","series-title":"The Renoprotect Effect of FPS on Rats With Adriamycin-induced Glomerulosclerosis","author":"Wang","year":"2005"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0145","doi-asserted-by":"crossref","first-page":"109639","DOI":"10.1039\/C6RA18865F","article-title":"Rhabdomyolysis induced AKI via the regulation of endoplasmic reticulum stress and oxidative stress in PTECs","volume":"6","author":"Feng","year":"2016","journal-title":"RSC Adv"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0150","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1111\/1440-1681.12633","article-title":"Evaluations of lipid peroxidation and inflammation in short-term glycerol-induced acute kidney injury in rats","volume":"43","author":"Nara","year":"2016","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0155","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.3892\/ijmm.2015.2095","article-title":"Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-kappa B signaling pathway in vivo and in vitro","volume":"35","author":"Wang","year":"2015","journal-title":"Int J Mol Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0160","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1002\/dmrr.2841","article-title":"Diabetic nephropathy in type 1 diabetes: a review of early natural history, pathogenesis, and diagnosis","volume":"33","author":"Papadopoulou-Marketou","year":"2017","journal-title":"Diabetes Metab Res Rev"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0165","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.3390\/md12063292","article-title":"The protective effect of fucoidan in rats with streptozotocin-induced diabetic nephropathy","volume":"12","author":"Wang","year":"2014","journal-title":"Mar Drugs"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0170","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jff.2017.01.031","article-title":"Renoprotective effect of fucoidan from Acaudina molpadioides in streptozotocin\/high fat diet-induced type 2 diabetic mice","volume":"31","author":"Hu","year":"2017","journal-title":"J Funct Foods"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0175","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s10811-016-0942-0","article-title":"Low molecular weight fucoidan ameliorates the inflammation and glomerular filtration function of diabetic nephropathy","volume":"29","author":"Xu","year":"2016","journal-title":"J Appl Phycol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0180","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ijbiomac.2016.05.081","article-title":"Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy","volume":"91","author":"Xu","year":"2016","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0185","first-page":"307","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure and its antioxidant mechanism","volume":"14","author":"Shi","year":"2015","journal-title":"Int J Clin Exp"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0190","first-page":"33","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of 30 patients with chronic renal failure","volume":"18","author":"Tao","year":"2014","journal-title":"Chin Natl Folk Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0195","first-page":"273","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure","volume":"31","author":"Li","year":"2015","journal-title":"Chin Med Pharmacol Clin"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0200","first-page":"59","article-title":"Effect of Haikun Shenxi Capsule on oxidative stress in chronic renal failure patients","volume":"52","author":"Qian","year":"2018","journal-title":"Shanghai J Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0205","first-page":"399","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure","author":"Cao","year":"2013","journal-title":"Mil Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0210","first-page":"56","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure","author":"Jin","year":"2013","journal-title":"Chin Community physician"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0215","first-page":"25","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure","author":"Zhang","year":"2012","journal-title":"J Anhui Coll Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0220","first-page":"404","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure","author":"Zhou","year":"2012","journal-title":"SiChun Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0225","first-page":"2020","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of 98 patients with chronic renal failure","author":"Zhang","year":"2010","journal-title":"GuangMing Tradit Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0230","first-page":"142","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of 32 patients with chronic renal failure","volume":"142","author":"Du","year":"2008","journal-title":"Shenyang Force Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0235","first-page":"1512","article-title":"Study on clinical effect of Haikunshenxi capsules and ShenShuai Ning in treatment of 30 patients with chronic renal failure","volume":"10","author":"Huo","year":"2013","journal-title":"HeBei Tradit Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0240","first-page":"92","article-title":"Study on clinical effect of Haikunshenxi capsules and Chuan Gongqin injection in treatment of patients with chronic renal failure","volume":"26","author":"Sun","year":"2013","journal-title":"Chin Health Ind"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0245","first-page":"62","article-title":"Study on clinical effect of Haikunshenxi capsules and Xue Bijing in treatment of patients with chronic renal failure","volume":"23","author":"Dang","year":"2013","journal-title":"J Clin Ration Drug Use"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0250","first-page":"2409","article-title":"Study on clinical effect of Haikunshenxi capsules and -Ketoacid in treatment of patients with chronic renal failure","volume":"22","author":"Li","year":"2013","journal-title":"Mod J Integr Tradit Chin West Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0255","first-page":"75","article-title":"Study on clinical effect of Haikunshenxi capsules and Shen Kang injection in treatment of 150 patients with chronic renal failure","volume":"13","author":"Yang","year":"2013","journal-title":"J Clin Ration Drug Use"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0260","article-title":"Study on clinical effect of Haikunshenxi capsules and salviae mihiorrhizae composite injection in treatment of patients with chronic renal failure","author":"Feng","year":"2013","journal-title":"Mod J Integr Tradit Chin West Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0265","first-page":"66","article-title":"Study on clinical effect of Haikunshenxi capsules and Shen shuai no 1 in treatment of patients with early and middle stage chronic renal failure","volume":"2","author":"Mo","year":"2013","journal-title":"J Liaoning Med Coll"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0270","first-page":"892","article-title":"Study on clinical effect of multi-drug combination in treatment of 57 patients with chronic renal failure","volume":"7","author":"Ru","year":"2013","journal-title":"Med Theory Pract"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0275","first-page":"1","article-title":"Study on clinical effect of Haikunshenxicapsules and Shenkanginjection in treatment of patients with chronic renal failure","volume":"9","author":"Li","year":"2013","journal-title":"Inner Mong Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0280","first-page":"41","article-title":"Study on clinical effect of Haikunshenxi capsules and Shenkang injection in treatment of patients with chronic renal failure","volume":"1","author":"Ding","year":"2013","journal-title":"Chin Med Front"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0285","first-page":"66","article-title":"Study on clinical effect of Haikunshenxi capsules and Shenkang injection in treatment of patients with chronic renal failure","volume":"11","author":"Du","year":"2012","journal-title":"Clin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0290","first-page":"451","article-title":"Study on clinical effect of Haikunshenxi capsules and salviae mihiorrhizae composite injection in treatment of patients with chronic renal failure","volume":"5","author":"Xu","year":"2012","journal-title":"HuaiHai Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0295","first-page":"741","article-title":"Camparation study on clinical effect of Haikunshenxi capsules and niaoDuQing capsule in treatment of patients with chronic renal failure","volume":"8","author":"Shu","year":"2012","journal-title":"Chin J Integr Tradit West Nephrol"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0300","first-page":"681","article-title":"Study on clinical effect of Haikunshenxi capsules and Levamlodipine Besylate in treatment of patients with chronic renal failure","volume":"8","author":"Lu","year":"2011","journal-title":"Chin Clin Res"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0305","first-page":"754","article-title":"Study on clinical effect of Haikunshenxi capsules and Da bu yin wan he danggui bu xue tang in treatment of patients with chronic renal failure","volume":"7","author":"Yan","year":"2012","journal-title":"J Shanxi Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0310","first-page":"526","article-title":"Study on clinical effect of Haikunshenxi capsules and Chinese herbal high breech enema in treatment of 65 patients with chronic renal failure","volume":"4","author":"Jiang","year":"2012","journal-title":"He Bei Tradit Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0315","first-page":"306","article-title":"Study on clinical effect of Haikun Shenxi combined with benazepril hydrochloride tablets in the treatment of stage III of chronic kidney disease","volume":"4","author":"Li","year":"2012","journal-title":"Chin Pharm"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0320","first-page":"404","article-title":"Study on clinical effect of Haikunshenxi capsules and Uremic granules in treatment of patients with chronic renal failure","volume":"4","author":"Qiu","year":"2011","journal-title":"Shan Xi Tradit Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0325","first-page":"107","article-title":"Study on clinical effect of Haikunshenxi capsules and Ligustrazine hydrochloride injection in treatment of patients with chronic renal failure","volume":"14","author":"Hao","year":"2011","journal-title":"Shang Dong Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0330","first-page":"23","article-title":"Study on clinical effect of Haikunshenxi capsules and dialectical in treatment of patients with chronic renal failure","volume":"33","author":"Li","year":"2011","journal-title":"J Hu Bei Tradit Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0335","first-page":"2024","article-title":"Study on clinical effect of Haikunshenxi capsules and -Ketoacid in treatment of patients with chronic renal failure","volume":"13","author":"Wang","year":"2010","journal-title":"J Qiqihar Med Coll"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0340","first-page":"748","article-title":"Study on clinical effect of Haikunshenxi capsules in treatment of non-dialysis patients with chronic renal failure","volume":"28","author":"Zhang","year":"2009","journal-title":"Clin Med Pract"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0345","first-page":"112","article-title":"Study on clinical effect of Haikunshenxi capsules and Jin Shuibao in treatment of patients with chronic renal failure","volume":"1","author":"Tao","year":"2008","journal-title":"Chin Pract Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0350","first-page":"446","article-title":"Study on clinical effect of Haikunshenxi capsules and renal failure II retention Enema Jin Shuibao in treatment of patients with chronic renal failure","volume":"5","author":"Yun","year":"2005","journal-title":"Pract J Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0355","first-page":"527","article-title":"Clinical nursing of Haikun Shenxi and Yudou decoction in treating renal pelvis proteinuria","volume":"14","author":"Zhang","year":"2014","journal-title":"The World's Latest Med Inf Abstr"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0360","first-page":"1096","article-title":"Study on clinical effect of Haikunshenxi capsules and Corbrin capsule in treatment of patients with chronic renal failure","volume":"20","author":"Huang","year":"2014","journal-title":"Chin J Basic Med Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0365","first-page":"238","article-title":"Study on clinical effect of Haikunshenxi capsules and Allopurinol tables in treatment of patients with chronic renal failure","volume":"9","author":"Lv","year":"2015","journal-title":"Chin Mod Med Appl"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0370","first-page":"157","article-title":"Study on clinical effect of Haikunshenxi capsules and Shenkang injection in treatment of 42 patients with chronic renal failure","volume":"6","author":"Zhao","year":"2015","journal-title":"China Health Stand Manag"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0375","first-page":"68","article-title":"Study on clinical effect of Haikunshenxi capsules and Yin Xing Da Mo injection in treatment of patients with chronic renal failure","volume":"21","author":"Tang","year":"2014","journal-title":"Chin Contemp Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0380","first-page":"897","article-title":"Study on clinical effect of Shenshuai recipe combined with Chinese herbal medicine in treatment of 90 patients with chronic renal failure at 2-4 stages","volume":"30","author":"Huang","year":"2014","journal-title":"J Changchun Univ Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0385","first-page":"3641","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with bi Xue Jing in treatment of patients with chronic renal failure","volume":"2","author":"Qin","year":"2015","journal-title":"Clin Med Lit Electron J"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0390","first-page":"17","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with Corbrin capsule in treatment of patients with chronic renal failure","volume":"24","author":"Hu","year":"2015","journal-title":"Henan Med Res"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0395","first-page":"350","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with sodium ferulic in treatment of patients with chronic renal failure","volume":"31","author":"Cao","year":"2016","journal-title":"Mod Med Clin"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0400","first-page":"99","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with uremic granules in treatment of patients with chronic renal failure at 2-4 stages","volume":"14","author":"He","year":"2016","journal-title":"Chin Mod Med Distance Educ"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0405","first-page":"571","article-title":"Safety and efficacy of Haikun Shenxi capsule combined with Ligustrazine injection for chronic renal insufficiency","volume":"27","author":"Huang","year":"2016","journal-title":"J Aerosp Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0410","article-title":"Therapeutic effect of febuxostat tables combined with Haikun Shenxi capsule on chronic kidney disease complicated with hyperuricemia","volume":"17","author":"Yang","year":"2017","journal-title":"Eval Anal Drug Use Chin Hosp"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0415","first-page":"113","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with allopurinol tables in treatment of patients with chronic renal failure","volume":"11","author":"Zhang","year":"2017","journal-title":"Chin Mod Med Appl"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0420","first-page":"43","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with -ketoacid in treatment of patients with chronic renal failure","volume":"10","author":"Tang","year":"2017","journal-title":"J Clin Ration Drug Use"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0425","first-page":"57+70","article-title":"Therapeutic effect of Chinese and Western medicine combined with Haikun Shenxi capsule on nephrotic syndrome","volume":"36","author":"Li","year":"2017","journal-title":"Inner Mong Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0430","first-page":"61","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with traditional Chinese medicine fumigation in treatment of patients with chronic renal failure","volume":"9","author":"Liao","year":"2017","journal-title":"TCM Clin Res"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0435","first-page":"36","article-title":"Study on clinical effect of Haikun Shenxi capsule in treatment of 50 patients with diabetic nephropathy","volume":"6","author":"Xu","year":"2012","journal-title":"J Gansu Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0440","first-page":"72","article-title":"Study on clinical effect of Haikun Shenxi capsule in treatment of patients with diabetic nephropathy at early stage","volume":"7","author":"Yao","year":"2010","journal-title":"Pract Clin Med J"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0445","first-page":"111","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with Qiangbenhuangsuangai in treatment of patients with diabetic nephropathy","volume":"3","author":"Ding","year":"2012","journal-title":"Chin Med Sci"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0450","first-page":"2124","article-title":"Study on clinical effect of Haikun Shenxi capsule combined with Ke Luo Xin in treatment of patients with diabetic nephropathy","volume":"41","author":"Li","year":"2014","journal-title":"Liaoning J Tradit Chin Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0455","first-page":"241","article-title":"Clinical observation of irbesartan combined with Haikun Shenxi in the treatment of senile diabetic nephropathy","volume":"9","author":"Xin","year":"2017","journal-title":"Integr Chin West Med"},{"key":"10.1016\/bs.pmbts.2019.03.011_bb0460","first-page":"15+18","article-title":"Clinical observation of irbesartan combined with Haikun Shenxi in the treatment of senile diabetic nephropathy","volume":"5","author":"Zhang","year":"2018","journal-title":"Clin Med Lit Electron J"}],"container-title":["Progress in Molecular Biology and Translational Science","Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877117319300560?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877117319300560?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T20:45:00Z","timestamp":1607201100000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1877117319300560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"ISBN":["9780128177402"],"references-count":91,"URL":"https:\/\/doi.org\/10.1016\/bs.pmbts.2019.03.011","relation":{},"ISSN":["1877-1173"],"issn-type":[{"value":"1877-1173","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]}}}