{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T04:01:39Z","timestamp":1787889699760,"version":"build-2784847793"},"reference-count":16,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T00:00:00Z","timestamp":1606176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aaceclinicalcasereports.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["AACE Clinical Case Reports"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.aace.2020.11.015","type":"journal-article","created":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T14:00:31Z","timestamp":1609423231000},"page":"57-60","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Bilateral Charcot Neuroarthropathy in Pregnancy: A Case Report and\u00a0Review of the Influence of Pregnancy Hormones on Ligament\u00a0Laxity"],"prefix":"10.1016","volume":"7","author":[{"given":"Rebecca","family":"Rogers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ketan K.","family":"Dhatariya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.aace.2020.11.015_bib1","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/dme.12754","article-title":"Charcot foot syndrome","volume":"32","author":"Jeffcoate","year":"2015","journal-title":"Diabetic Med"},{"issue":"1","key":"10.1016\/j.aace.2020.11.015_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12902-019-0422-z","article-title":"An atypical and bilateral presentation of Charcot foot disease","volume":"19","author":"Loupa","year":"2019","journal-title":"BMC Endocr Disord"},{"issue":"12","key":"10.1016\/j.aace.2020.11.015_bib3","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s11892-014-0561-6","article-title":"The Charcot foot as a complication of diabetic neuropathy","volume":"14","author":"Mascarenhas","year":"2014","journal-title":"Curr Diab Rep"},{"issue":"1","key":"10.1016\/j.aace.2020.11.015_bib4","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1757-1146-6-30","article-title":"Developing an evidence-based clinical pathway for the assessment, diagnosis and management of acute Charcot neuro-arthropathy: a systematic review","volume":"6","author":"Milne","year":"2013","journal-title":"J\u00a0Foot Ankle Res"},{"key":"10.1016\/j.aace.2020.11.015_bib5","doi-asserted-by":"crossref","first-page":"21117","DOI":"10.3402\/dfa.v4i0.21117","article-title":"An overview of Charcot foot pathophysiology","volume":"4","author":"Kaynak","year":"2013","journal-title":"Diabet Foot Ankle"},{"issue":"4","key":"10.1016\/j.aace.2020.11.015_bib6","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jdiacomp.2012.04.016","article-title":"Oxidative stress and inflammation in hyperglycemic crises and resolution with insulin: implications for the acute and chronic complications of hyperglycemia","volume":"26","author":"Chaudhuri","year":"2012","journal-title":"J\u00a0Diabetes Complications"},{"key":"10.1016\/j.aace.2020.11.015_bib7","doi-asserted-by":"crossref","first-page":"109439","DOI":"10.1016\/j.mehy.2019.109439","article-title":"Mitochondrial dysfunction is the cause of one of the earliest changes seen on magnetic resonance imaging in Charcot neuroarthropathy \u2013 oedema of the small muscles in the foot","volume":"134","author":"Lymbouris","year":"2020","journal-title":"Med Hypotheses"},{"issue":"1","key":"10.1016\/j.aace.2020.11.015_bib8","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s00125-011-2354-7","article-title":"Audit of acute Charcot's disease in the UK: the CDUK study","volume":"55","author":"Game","year":"2012","journal-title":"Diabetologia"},{"issue":"3","key":"10.1016\/j.aace.2020.11.015_bib9","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1007\/s11999-014-4059-y","article-title":"Classifications in brief: Eichenholtz classification of Charcot arthropathy","volume":"473","author":"Rosenbaum","year":"2015","journal-title":"Clin Orthop Relat Res"},{"issue":"4","key":"10.1016\/j.aace.2020.11.015_bib10","doi-asserted-by":"crossref","first-page":"198","DOI":"10.11622\/smedj.2016074","article-title":"Risk factors of diabetic foot Charcot arthropathy: a case-control study at a Malaysian tertiary care centre","volume":"57","author":"Fauzi","year":"2016","journal-title":"Singapore Med J"},{"issue":"9","key":"10.1016\/j.aace.2020.11.015_bib11","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jsbmb.2017.06.008","article-title":"The effect of estrogen on tendon and ligament metabolism and function","volume":"172","author":"Leblanc","year":"2017","journal-title":"J\u00a0Steroid Biochem Mol Biol"},{"issue":"2","key":"10.1016\/j.aace.2020.11.015_bib12","first-page":"144","article-title":"Hormonal changes throughout the menstrual cycle and increased anterior cruciate ligament laxity in females","volume":"34","author":"Heitz","year":"1999","journal-title":"J\u00a0Athl Train"},{"issue":"9","key":"10.1016\/j.aace.2020.11.015_bib13","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.2106\/JBJS.RVW.18.00198","article-title":"The menstrual cycle may affect anterior knee laxity and the rate of anterior cruciate ligament rupture: a systematic review and meta-analysis","volume":"7","author":"Somerson","year":"2019","journal-title":"JBJS Rev"},{"issue":"2","key":"10.1016\/j.aace.2020.11.015_bib14","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1177\/03635465020300020601","article-title":"The effect of the menstrual cycle on anterior cruciate ligament injuries in women as determined by hormone levels","volume":"30","author":"Wojtys","year":"2002","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.aace.2020.11.015_bib15","first-page":"7","article-title":"The role of the hormone relaxin in human reproduction and pelvic girdle relaxation","volume":"88","author":"MacLennan","year":"1991","journal-title":"Scand J Rheumatol Suppl"},{"issue":"8822","key":"10.1016\/j.aace.2020.11.015_bib16","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/0140-6736(92)92295-Q","article-title":"Maternal relaxin concentrations in diabetic pregnancy","volume":"340","author":"Steinetz","year":"1992","journal-title":"Lancet"}],"container-title":["AACE Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2376060520310166?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2376060520310166?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T06:31:52Z","timestamp":1762497112000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2376060520310166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S2376060520310166"],"URL":"https:\/\/doi.org\/10.1016\/j.aace.2020.11.015","relation":{},"ISSN":["2376-0605"],"issn-type":[{"value":"2376-0605","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bilateral Charcot Neuroarthropathy in Pregnancy: A Case Report and\u00a0Review of the Influence of Pregnancy Hormones on Ligament\u00a0Laxity","name":"articletitle","label":"Article Title"},{"value":"AACE Clinical Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aace.2020.11.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 AACE. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}