{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:36:54Z","timestamp":1776400614120,"version":"3.51.2"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Anatomy - Anatomischer Anzeiger"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.aanat.2012.09.003","type":"journal-article","created":{"date-parts":[[2012,10,6]],"date-time":"2012-10-06T20:02:13Z","timestamp":1349553733000},"page":"122-127","source":"Crossref","is-referenced-by-count":28,"title":["Changes in Interleukin-1 alpha serum levels after transplantation of umbilical cord blood cells in a model of perinatal hypoxic-ischemic brain damage"],"prefix":"10.1016","volume":"195","author":[{"given":"Katja","family":"Rosenkranz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Tenbusch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"May","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrin","family":"Marcus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carola","family":"Meier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.aanat.2012.09.003_bib0005","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1742-4658.2008.06766.x","article-title":"Post-ischemic brain damage: pathophysiology and role of inflammatory mediators","volume":"276","author":"Amantea","year":"2009","journal-title":"FEBS J."},{"key":"10.1016\/j.aanat.2012.09.003_bib0010","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/0149-7634(95)00026-7","article-title":"The role of inflammation and cytokines in brain injury","volume":"20","author":"Arvin","year":"1996","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.aanat.2012.09.003_bib0015","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1006\/clin.1997.4331","article-title":"IL-10 suppresses experimental autoimmune neuritis and down-regulates TH1-type immune responses","volume":"83","author":"Bai","year":"1997","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0020","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/ana.22670","article-title":"Cell therapy for neonatal hypoxia-ischemia and cerebral palsy","volume":"71","author":"Bennet","year":"2012","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0025","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/S0028-3908(97)00139-1","article-title":"Neonatal cerebral hypoxia-ischemia: the effect of adenosine receptor antagonists","volume":"36","author":"Bona","year":"1997","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.aanat.2012.09.003_bib0030","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1161\/01.STR.0000141680.49960.d7","article-title":"Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke","volume":"35","author":"Borlongan","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.aanat.2012.09.003_bib0035","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S1875-9572(08)60017-0","article-title":"Infusion of human umbilical cord blood cells ameliorates hind limb dysfunction in experimental spinal cord injury through anti-inflammatory, vasculogenic and neurotrophic mechanisms","volume":"49","author":"Chen","year":"2008","journal-title":"Pediatr. Neonatol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0040","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1161\/hs1101.098367","article-title":"Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats","volume":"32","author":"Chen","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.aanat.2012.09.003_bib0045","doi-asserted-by":"crossref","first-page":"e20194","DOI":"10.1371\/journal.pone.0020194","article-title":"Human umbilical cord blood cells restore brain damage induced changes in rat somatosensory cortex","volume":"6","author":"Geissler","year":"2011","journal-title":"PloS ONE"},{"key":"10.1016\/j.aanat.2012.09.003_bib0050","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1203\/00006450-199601000-00006","article-title":"Hypoxic-ischemic brain injury induces an acute microglial reaction in perinatal rats","volume":"39","author":"Ivacko","year":"1996","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.aanat.2012.09.003_bib0055","first-page":"1","article-title":"Anoxic-ischemic encephalopathy in rats","volume":"36","author":"Levine","year":"1960","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0060","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s10456-005-5208-4","article-title":"Autocrine role of interleukin-8 in induction of endothelial cell proliferation, survival, migration and MMP-2 production and angiogenesis","volume":"8","author":"Li","year":"2005","journal-title":"Angiogenesis"},{"key":"10.1016\/j.aanat.2012.09.003_bib0065","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S1875-9572(09)60065-6","article-title":"Human umbilical cord blood cells protect against hypothalamic apoptosis and systemic inflammation response during heatstroke in rats","volume":"50","author":"Liu","year":"2009","journal-title":"Pediatr. Neonatol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0070","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1186\/1742-2094-8-186","article-title":"Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues","volume":"8","author":"Luheshi","year":"2011","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.aanat.2012.09.003_bib0075","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1203\/01.pdr.0000197309.08852.f5","article-title":"Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells","volume":"59","author":"Meier","year":"2006","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.aanat.2012.09.003_bib0080","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.exphem.2007.03.019","article-title":"Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro","volume":"35","author":"Neuhoff","year":"2007","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0085","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.expneurol.2006.04.001","article-title":"Cytokines produced by cultured human umbilical cord blood (HUCB) cells: implications for brain repair","volume":"199","author":"Newman","year":"2006","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0090","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1007\/BF00229041","article-title":"Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture","volume":"92","author":"Nikkhah","year":"1993","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.aanat.2012.09.003_bib0095","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/ana.22419","article-title":"Neuronal cell death in neonatal hypoxia-ischemia","volume":"69","author":"Northington","year":"2011","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0100","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/0165-3806(94)00194-5","article-title":"Glial responses to hypoxic\/ischemic encephalopathy in neonatal rat cerebrum","volume":"84","author":"Ohno","year":"1995","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.aanat.2012.09.003_bib0105","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1089\/scd.2009.0049","article-title":"Human cord blood transplantation in a neonatal rat model of hypoxic-ischemic brain damage: functional outcome related to neuroprotection in the striatum","volume":"19","author":"Pimentel-Coelho","year":"2010","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.aanat.2012.09.003_bib0110","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic-ischemic brain damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0115","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1002\/jnr.22292","article-title":"The chemokine SDF-1\/CXCL12 contributes to the \u2018homing\u2019 of umbilical cord blood cells to a hypoxic-ischemic lesion in the rat brain","volume":"88","author":"Rosenkranz","year":"2010","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.aanat.2012.09.003_bib0120","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s00441-012-1401-0","article-title":"Transplantation of human umbilical cord blood cells mediated beneficial effects on apoptosis, angiogenesis and neuronal survival after hypoxic-ischemic brain injury in rats","volume":"348","author":"Rosenkranz","year":"2012","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.aanat.2012.09.003_bib0125","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.aanat.2011.03.005","article-title":"Umbilical cord blood cell transplantation after brain ischemia\u2014from recovery of function to cellular mechanisms","volume":"193","author":"Rosenkranz","year":"2011","journal-title":"Ann. Anat."},{"key":"10.1016\/j.aanat.2012.09.003_bib0130","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0301-0082(98)00069-0","article-title":"Reactive microgliosis","volume":"57","author":"Streit","year":"1999","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0135","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.neuroscience.2007.08.034","article-title":"The cellular and behavioral consequences of interleukin-1 alpha penetration through the blood\u2013brain barrier of neonatal rats: a critical period for efficacy","volume":"150","author":"Tohmi","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.aanat.2012.09.003_bib0140","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1242\/jeb.01064","article-title":"Hypoxia-ischemia in the immature brain","volume":"207","author":"Vannucci","year":"2004","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0145","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.expneurol.2006.03.017","article-title":"Cord blood rescues stroke-induced changes in splenocyte phenotype and function","volume":"199","author":"Vendrame","year":"2006","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0150","series-title":"Neurology of the Newborn","author":"Volpe","year":"2008"},{"key":"10.1016\/j.aanat.2012.09.003_bib0155","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S1474-4422(08)70294-1","article-title":"Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances","volume":"8","author":"Volpe","year":"2009","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.aanat.2012.09.003_bib0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2012.05.066","article-title":"Neuroglial activation and Cx43 expression are reduced upon transplantation of human umbilical cord blood cells after perinatal hypoxic-ischemic injury","author":"Wasielewski","year":"2012","journal-title":"Brain Res."},{"key":"10.1016\/j.aanat.2012.09.003_bib0165","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1111\/j.1582-4934.2008.00671.x","article-title":"Mannitol facilitates neurotrophic factor upregulation and behavioral recovery in neonatal hypoxic-ischemic rats with human umbilical cord blood grafts","volume":"14","author":"Yasuhara","year":"2010","journal-title":"J. Cell. Mol. Med."}],"container-title":["Annals of Anatomy - Anatomischer Anzeiger"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0940960212001422?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0940960212001422?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T02:38:10Z","timestamp":1714444690000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0940960212001422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S0940960212001422"],"URL":"https:\/\/doi.org\/10.1016\/j.aanat.2012.09.003","relation":{},"ISSN":["0940-9602"],"issn-type":[{"value":"0940-9602","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}