{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T12:56:15Z","timestamp":1774270575706,"version":"3.50.1"},"reference-count":45,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,30]],"date-time":"2016-07-30T00:00:00Z","timestamp":1469836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["e-aat.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiologica Taiwanica"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.aat.2016.11.002","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T02:16:54Z","timestamp":1484273814000},"page":"121-128","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Influence of perioperative nonsteroidal anti-inflammatory drugs on complications after gastrointestinal surgery: A meta-analysis"],"prefix":"10.1016","volume":"54","author":[{"given":"Fang","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shijiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youli","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cunming","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.aat.2016.11.002_bib1","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1055\/s-0029-1202888","article-title":"Fast track colorectal surgery","volume":"22","author":"Counihan","year":"2009","journal-title":"Clin Colon Rectal Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib2","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1097\/00000542-200506000-00027","article-title":"Effects of non-steroidal anti-inflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials","volume":"102","author":"Marret","year":"2005","journal-title":"Anesthesiology"},{"key":"10.1016\/j.aat.2016.11.002_bib3","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1007\/s00268-005-0613-9","article-title":"Review of the pathophysiology and management of postoperative ileus","volume":"30","author":"Mattei","year":"2006","journal-title":"Word J Surg"},{"issue":"6","key":"10.1016\/j.aat.2016.11.002_bib4","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1097\/00000542-200506000-00004","article-title":"Postoperative opioid sparing to hasten recovery","volume":"102","author":"Kehlet","year":"2005","journal-title":"Anesthesiology"},{"key":"10.1016\/j.aat.2016.11.002_bib5","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/0140-6736(90)92341-E","article-title":"Inhibitory effect of non-steroidal anti-inflammatory drugs on mucosal cell proliferation associated with gastric ulcer healing","volume":"336","author":"Levi","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.aat.2016.11.002_bib6","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1023\/A:1018846912032","article-title":"Effects of cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal anti-inflammatory drugs on mucosal ulcerogenic and healing responses of the stomach","volume":"43","author":"Ukawa","year":"1998","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.aat.2016.11.002_bib7","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ejphar.2004.10.019","article-title":"Angiogenesis, cell proliferation and apoptosis in gastric ulcer healing. Effect of a selective cox-2 inhibitor","volume":"505","author":"S\u00e1nchez-Fidalgo","year":"2004","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.aat.2016.11.002_bib8","first-page":"804","article-title":"A meta-analysis of severe upper gastrointestinal complications of non-steroidal anti-inflammatory drugs","volume":"29","author":"Ofman","year":"2002","journal-title":"J Rheumatol"},{"key":"10.1016\/j.aat.2016.11.002_bib9","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1001\/jama.296.13.jrv60011","article-title":"Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and non-selective inhibitors of cyclooxygenase 2","volume":"296","author":"McGettigan","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.aat.2016.11.002_bib10","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1007\/s11605-008-0594-8","article-title":"Mechanical bowel preparation in intestinal surgery: a meta-analysis and review of the literature","volume":"12","author":"Pineda","year":"2008","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib11","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-2482-6-2","article-title":"Single-versus two-layer intestinal anastomosis: a meta-analysis of randomized controlled trials","volume":"6","author":"Shikata","year":"2006","journal-title":"BMC Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib12","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S1072-7515(99)00028-9","article-title":"The failed gastrointestinal anastomosis: an inevitable catastrophe?","volume":"188","author":"Pickleman","year":"1999","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib13","first-page":"364","article-title":"A multivariate analysis of factors contributing to leakage of intestinal anastomoses","volume":"184","author":"Golub","year":"1997","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib14","first-page":"299","article-title":"Host-related predictive factors for anastomotic leakage following large bowel resections for colorectal cancer","volume":"17","author":"Iancu","year":"2008","journal-title":"J Gastrointest Liver Dis"},{"key":"10.1016\/j.aat.2016.11.002_bib15","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/nrgastro.2009.185","article-title":"Anastomoses of the lower gastrointestinal tract","volume":"6","author":"Nandakumar","year":"2009","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.aat.2016.11.002_bib16","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1046\/j.1365-2168.1999.01165.x","article-title":"Smoking and alcohol abuse are major risk factors for anastomotic leakage in colorectal surgery","volume":"86","author":"S\u00f8rensen","year":"1999","journal-title":"Br J Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib17","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1007\/s00384-007-0317-8","article-title":"\u201cFast-track\u201d rehabilitation after colonic surgery in elderly patients\u2014is it feasible?","volume":"22","author":"Scharfenberg","year":"2007","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.aat.2016.11.002_bib18","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1001\/archsurg.2009.170","article-title":"Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations","volume":"144","author":"Lassen","year":"2009","journal-title":"Arch Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib19","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/bjs.6445","article-title":"Determinants of outcome after colorectal resection within an enhanced recovery program","volume":"96","author":"Hendry","year":"2009","journal-title":"Br J Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib20","doi-asserted-by":"crossref","first-page":"e1000100","DOI":"10.1371\/journal.pmed.1000100","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"6","author":"Liberati","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.aat.2016.11.002_bib21","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1002\/bjs.9614","article-title":"Impact of postoperative non-steroidal anti-inflammatory drugs on adverse events after gastrointestinal surgery","volume":"101","year":"2014","journal-title":"Br J Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib22","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1399-6576.2005.00674.x","article-title":"Effect of adding ketorolac to intravenous morphine patient-controlled analgesia on bowel function in colorectal surgery patients\u2014a prospective, randomized, double-blind study","volume":"49","author":"Chen","year":"2005","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.aat.2016.11.002_bib23","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1097\/AJP.0b013e31819a506b","article-title":"Opioid-sparing effects of ketorolac and its correlation with the recovery of postoperative bowel function in colorectal surgery patients: a prospective randomized double-blinded study","volume":"25","author":"Chen","year":"2009","journal-title":"Clin J Pain"},{"key":"10.1016\/j.aat.2016.11.002_bib24","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1002\/bjs.8691","article-title":"Risk of anastomotic leakage with non-steroidal anti-inflammatory drugs in colorectal surgery","volume":"99","author":"Gorissen","year":"2012","journal-title":"Br J Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib25","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1002\/bjs.6598","article-title":"Cyclo-oxygenase 2 inhibitors and the risk of anastomotic leakage after fast-track colonic surgery","volume":"96","author":"Holte","year":"2009","journal-title":"Br J Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib26","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1159\/000193329","article-title":"Increased risk of anastomotic leakage with diclofenac treatment after laparoscopic colorectal surgery","volume":"26","author":"Klein","year":"2009","journal-title":"Dig Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib27","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s10350-006-0860-3","article-title":"Severe complications with diclofenac after colonic resection","volume":"50","author":"Rosenberg","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.aat.2016.11.002_bib28","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1007\/s00464-007-9335-4","article-title":"Optimizing recovery after laparoscopic colon surgery (ORAL-CS): effect of intravenous ketorolac on length of hospital stay","volume":"21","author":"Schlachta","year":"2007","journal-title":"Surg Endosc"},{"key":"10.1016\/j.aat.2016.11.002_bib29","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1463-1318.2006.00998.x","article-title":"Prospective randomized, double-blind, placebo-controlled study of pre- and postoperative administration of a COX-2-specific inhibitor as opioid-sparing analgesia in major colorectal surgery","volume":"9","author":"Sim","year":"2007","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.aat.2016.11.002_bib30","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1111\/j.1365-2036.2009.04126.x","article-title":"Clinical trial: the impact of cyclooxygenase inhibitors on gastrointestinal recovery after major surgery-a randomized double blind controlled trial of celecoxib or diclofenac vs. placebo","volume":"30","author":"Wattchow","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.aat.2016.11.002_bib31","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/BF03016307","article-title":"Intravenous flurbiprofen axetil accelerates restoration of bowel function after colorectal surgery","volume":"55","author":"Xu","year":"2008","journal-title":"Can J Anaesth"},{"key":"10.1016\/j.aat.2016.11.002_bib32","series-title":"Clinical observation of postoperative intravenous analgesia after gastrointestinal by flurbiprofen axetil compound small dose fentanyl","author":"Yang","year":"2009"},{"key":"10.1016\/j.aat.2016.11.002_bib33","first-page":"161","article-title":"Research progress of non-steroidal drugs in clinical application and adverse reactions","volume":"5","author":"Hu","year":"2001","journal-title":"Anhui Med Pharm J"},{"key":"10.1016\/j.aat.2016.11.002_bib34","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1007\/s00268-014-2531-1","article-title":"Postoperative nonsteroidal anti-inflammatory drugs and risk of anastomotic leak: meta-analysis of clinical and experimental studies","volume":"38","author":"Bhangu","year":"2014","journal-title":"World J Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib35","first-page":"650","article-title":"Treatment of pain after spinal surgery in the recovery room by single does lornoxicam: a randomized, double blind, placebo controlled trial","volume":"87","author":"Thienthong","year":"2004","journal-title":"J\u00a0Med Assoc Thai"},{"key":"10.1016\/j.aat.2016.11.002_bib36","first-page":"32","article-title":"The comparison of fentanyl and buprenorphine for postoperative analgesia","volume":"12","author":"Wang","year":"2006","journal-title":"Henan J Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib37","first-page":"28","article-title":"Postoperative nausea and vomiting","volume":"15","author":"You","year":"1994","journal-title":"Archiv Foreign Med Anesthesiol Recovery"},{"key":"10.1016\/j.aat.2016.11.002_bib38","doi-asserted-by":"crossref","first-page":"213","DOI":"10.2165\/00003495-200059020-00005","article-title":"Prevention and treatment of postoperative nausea and vomiting","volume":"59","author":"Kovac","year":"2000","journal-title":"Drugs"},{"key":"10.1016\/j.aat.2016.11.002_bib39","first-page":"6","article-title":"NSAIDs induced gastrointestinal damage. Epidemiology, risk and prevention, with an evaluation of the role of misoprostol. An Asia-Pacific perspective and consensus","volume":"53","author":"Championg","year":"1997","journal-title":"Drugs"},{"key":"10.1016\/j.aat.2016.11.002_bib40","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1046\/j.1365-2168.2000.01595.x","article-title":"Postoperative ileus: a preventable event","volume":"87","author":"Holte","year":"2000","journal-title":"Br J Surg"},{"key":"10.1016\/j.aat.2016.11.002_bib41","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.3748\/wjg.v16.i17.2067","article-title":"Postoperative ileus: impact of pharmacological treatment, laparoscopic surgery and enhanced recovery pathways","volume":"16","author":"Augestad","year":"2010","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.aat.2016.11.002_bib42","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1053\/gast.2001.29605","article-title":"Prostanoid production via COX-2 as a causative mechanism of rodent postoperative ileus","volume":"121","author":"Schwarz","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.aat.2016.11.002_bib43","first-page":"268","article-title":"Perioperative NSAIDs: towards greater safety","volume":"2","author":"Merry","year":"1995","journal-title":"Pain Rev"},{"key":"10.1016\/j.aat.2016.11.002_bib44","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1743-3150.2004.00558.x","article-title":"Mechanisms of postoperative ileus","volume":"16","author":"Bauer","year":"2004","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.aat.2016.11.002_bib45","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1136\/gut.52.4.527","article-title":"COX-2-dependent inflammation increases spinal Fos expression during rodent postoperative ileus","volume":"52","author":"Kreiss","year":"2003","journal-title":"Gut"}],"container-title":["Acta Anaesthesiologica Taiwanica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875459716300698?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875459716300698?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T03:53:02Z","timestamp":1536119582000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1875459716300698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S1875459716300698"],"URL":"https:\/\/doi.org\/10.1016\/j.aat.2016.11.002","relation":{},"ISSN":["1875-4597"],"issn-type":[{"value":"1875-4597","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of perioperative nonsteroidal anti-inflammatory drugs on complications after gastrointestinal surgery: A meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Acta Anaesthesiologica Taiwanica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aat.2016.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016, Taiwan Society of Anesthesiologists. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}