{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T02:00:03Z","timestamp":1783216803333,"version":"3.54.6"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytical Biochemistry"],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1016\/j.ab.2007.01.009","type":"journal-article","created":{"date-parts":[[2007,1,16]],"date-time":"2007-01-16T19:38:30Z","timestamp":1168976310000},"page":"91-96","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Plasma methionine determination by capillary electrophoresis\u2013UV assay: Application on patients affected by retinal venous occlusive disease"],"prefix":"10.1016","volume":"363","author":[{"given":"Angelo","family":"Zinellu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Sotgia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Franca","family":"Usai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Zinellu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Posadino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Gaspa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Chessa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Pinna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Carta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Deiana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciriaco","family":"Carru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ab.2007.01.009_bib1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1146\/annurev.nutr.19.1.217","article-title":"Homocysteine metabolism","volume":"19","author":"Selhub","year":"1999","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.ab.2007.01.009_bib2","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0002-8703(00)90088-7","article-title":"Association between total homocyst(e)ine and the likelihood for a history of acute myocardial infarction by race and ethnicity: Results from the Third National Health and Nutrition Examination Survey","volume":"139","author":"Giles","year":"2000","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ab.2007.01.009_bib3","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S1474-4422(04)00826-9","article-title":"Homocysteine, B-vitamin supplementation, and stroke prevention: From observational to interventional trials","volume":"3","author":"Schwammenthal","year":"2004","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.ab.2007.01.009_bib4","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1023\/A:1022126100625","article-title":"Vitamins, homocysteine, and cardiovascular risk","volume":"16","author":"Graham","year":"2002","journal-title":"Cardiovasc. Drugs Ther."},{"key":"10.1016\/j.ab.2007.01.009_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s11745-001-0677-9","article-title":"Hyperhomocysteinemia and thrombosis","volume":"36","author":"Cattaneo","year":"2001","journal-title":"Lipids"},{"key":"10.1016\/j.ab.2007.01.009_bib6","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1056\/NEJM199101173240315","article-title":"Neural-tube defects and derangement of homocysteine metabolism","volume":"324","author":"Steegers-Theunissen","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ab.2007.01.009_bib7","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/S0015-0282(00)01595-8","article-title":"Hyperhomocysteinemia and recurrent early pregnancy loss: A meta-analysis","volume":"74","author":"Nelen","year":"2000","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ab.2007.01.009_bib8","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1093\/ajcn\/71.4.962","article-title":"Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine Study","volume":"71","author":"Vollset","year":"2000","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.ab.2007.01.009_bib9","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.bone.2006.03.004","article-title":"Homocysteine enhances apoptosis in human bone marrow stromal cells","volume":"39","author":"Kim","year":"2006","journal-title":"Bone"},{"key":"10.1016\/j.ab.2007.01.009_bib10","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0009-8981(02)00287-5","article-title":"Plasmatic homocysteine concentration and its relationship with complications associated to diabetes mellitus","volume":"326","author":"Agullo-Ortuno","year":"2002","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.ab.2007.01.009_bib11","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jns.2004.09.006","article-title":"Homocysteine, cerebrovascular disease, and brain atrophy","volume":"226","author":"Sachdev","year":"2004","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.ab.2007.01.009_bib12","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/PL00014300","article-title":"The metabolism of homocysteine: Pathways and regulation","volume":"157","author":"Finkelstein","year":"1998","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.ab.2007.01.009_bib13","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1042\/bj2980415","article-title":"Folate-deficiency-induced homocysteinaemia in rats: Disruption of S-adenosylmethionine\u2019s coordinate regulation of homocysteine metabolism","volume":"298","author":"Miller","year":"1994","journal-title":"Biochem. J."},{"key":"10.1016\/j.ab.2007.01.009_bib14","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1093\/jn\/136.6.1731S","article-title":"The Hordaland Homocysteine Study: A community-based study of homocysteine, its determinants, and associations with disease","volume":"136","author":"Refsum","year":"2006","journal-title":"J. Nutr."},{"key":"10.1016\/j.ab.2007.01.009_bib15","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1055\/s-2005-872397","article-title":"Dietary determinants of plasma homocysteine concentrations","volume":"5","author":"Verhoef","year":"2005","journal-title":"Semin. Vasc. Med."},{"key":"10.1016\/j.ab.2007.01.009_bib16","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1055\/s-2005-872396","article-title":"Genetic determinants of plasma total homocysteine","volume":"5","author":"Gellekink","year":"2005","journal-title":"Semin. Vasc. Med."},{"key":"10.1016\/j.ab.2007.01.009_bib17","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1073\/pnas.72.2.619","article-title":"o-Phthalaldehyde: Fluorogenic detection of primary amines in the picomole range\u2014Comparison with fluorescamine and ninhydrin","volume":"72","author":"Benson","year":"1975","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ab.2007.01.009_bib18","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0021-9673(01)90918-5","article-title":"o-Phthaldialdehyde precolumn derivatization and reversed-phase high-performance liquid chromatography of polypeptide hydrolysates and physiological fluids","volume":"266","author":"Jones","year":"1983","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.ab.2007.01.009_bib19","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0009-8981(87)90385-8","article-title":"High performance liquid chromatography of plasma amino acids using ortho-phthalaldehyde derivatisation","volume":"170","author":"Blundell","year":"1987","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.ab.2007.01.009_bib20","first-page":"59","article-title":"A rapid HPLC method for the measurement of ultra-low plasma methionine concentrations applicable to methionine depletion therapy","volume":"25","author":"Sun","year":"2005","journal-title":"Anticancer Res."},{"key":"10.1016\/j.ab.2007.01.009_bib21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1002\/(SICI)1522-2683(19990301)20:3<569::AID-ELPS569>3.0.CO;2-S","article-title":"Determining sulfur-containing amino acids by capillary electrophoresis: A fast novel method for total homocyst(e)ine human plasma","volume":"20","author":"Vecchione","year":"1999","journal-title":"Electrophoresis"},{"key":"10.1016\/j.ab.2007.01.009_bib22","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1002\/jssc.200500428","article-title":"Assay for the simultaneous determination of guanidinoacetic acid, creatinine, and creatine in plasma and urine by capillary electrophoresis UV-detection","volume":"29","author":"Zinellu","year":"2006","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.ab.2007.01.009_bib23","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ab.2005.01.045","article-title":"Plasma creatinine and creatine quantification by capillary electrophoresis diode array detector","volume":"342","author":"Zinellu","year":"2005","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.ab.2007.01.009_bib24","doi-asserted-by":"crossref","first-page":"4067","DOI":"10.1167\/iovs.06-0290","article-title":"Plasma homocysteine and cysteine levels in retinal vein occlusion","volume":"47","author":"Pinna","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ab.2007.01.009_bib25","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/S0955-2863(99)00033-9","article-title":"A new HPLC method for the simultaneous determination of oxidized and reduced plasma aminothiols using coulometric electrochemical detection","volume":"10","author":"Melnyk","year":"1999","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.ab.2007.01.009_bib26","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.aca.2005.04.089","article-title":"Simultaneous determination of total homocysteine, cysteine, and methionine in hypothyroid patients\u2019 plasma by liquid chromatography using platinum\/poly(methyl violet) modified electrode","volume":"545","author":"Xu","year":"2005","journal-title":"Anal. Chim. Acta."},{"key":"10.1016\/j.ab.2007.01.009_bib27","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.chroma.2005.04.084","article-title":"A new strategy for the selective determination of d-amino acids: Enzymatic and chemical modifications for pre-column derivatization","volume":"1078","author":"Oguri","year":"2005","journal-title":"J. Chromatogr. A"}],"container-title":["Analytical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003269707000267?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003269707000267?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T20:46:44Z","timestamp":1757710004000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003269707000267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["S0003269707000267"],"URL":"https:\/\/doi.org\/10.1016\/j.ab.2007.01.009","relation":{},"ISSN":["0003-2697"],"issn-type":[{"value":"0003-2697","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasma methionine determination by capillary electrophoresis\u2013UV assay: Application on patients affected by retinal venous occlusive disease","name":"articletitle","label":"Article Title"},{"value":"Analytical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ab.2007.01.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}