{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T13:08:51Z","timestamp":1792415331359,"version":"4.4.0"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytical Biochemistry"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.ab.2017.06.014","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T03:00:22Z","timestamp":1498705222000},"page":"93-98","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["A multiplex ARMS PCR approach to detection of common \u03b2-globin gene mutations"],"prefix":"10.1016","volume":"537","author":[{"given":"Kanchan K.","family":"Mishra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5135-4023","authenticated-orcid":false,"given":"Parizad","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipal S.","family":"Bhukhanvala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avani","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0645-6565","authenticated-orcid":false,"given":"Kanjaksha","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ab.2017.06.014_bib1","first-page":"75","article-title":"Thalassemia in Bombay: the role of medical genetics","volume":"68","author":"Sangani","year":"1990","journal-title":"Bull. WHO"},{"issue":"1","key":"10.1016\/j.ab.2017.06.014_bib2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1586\/ehm.09.74","article-title":"Global burden, distribution and prevention of thalassemias and hemoglobin E disorders","volume":"3","author":"Colah","year":"2010","journal-title":"Expert. Rev. Hematol."},{"issue":"13","key":"10.1016\/j.ab.2017.06.014_bib3","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1002\/pd.4706","article-title":"Challenges in prenatal diagnosis of beta thalassaemia: couples with normal HbA2 in one partner","volume":"35","author":"Gorivale","year":"2015","journal-title":"Prenat. Diagn"},{"issue":"2","key":"10.1016\/j.ab.2017.06.014_bib4","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1136\/jcp.2009.070391","article-title":"Effect of hydroxyurea on the transfusion requirements in patients with severe HbE- beta-thalassaemia: a genotypic and phenotypic study","volume":"63","author":"Italia","year":"2010","journal-title":"J.\u00a0Clin. Pathol."},{"issue":"6","key":"10.1016\/j.ab.2017.06.014_bib5","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/ijlh.12548","article-title":"Delta globin gene variations leading to reduction in HbA2 levels","volume":"38","author":"Hariharan","year":"2016","journal-title":"Int. J. Lab. Hematol."},{"issue":"1","key":"10.1016\/j.ab.2017.06.014_bib6","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/nrg978","article-title":"Recommendations for introducing genetics services in developing countries","volume":"4","author":"Alwan","year":"2002","journal-title":"Nat. Rev. Genet."},{"issue":"3","key":"10.1016\/j.ab.2017.06.014_bib7","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/(SICI)1097-0223(200003)20:3<194::AID-PD778>3.0.CO;2-3","article-title":"Prenatal diagnosis of thalassemia and other hemoglobinopathies in India","volume":"20","author":"Thakur","year":"2000","journal-title":"Prenat. Diagn."},{"issue":"3","key":"10.1016\/j.ab.2017.06.014_bib8","first-page":"18","article-title":"Hemoglobinopathies in South Gujarat population and incidence of anemia in them","author":"Patel","year":"2012","journal-title":"Indian J. Hum. Genet."},{"issue":"11","key":"10.1016\/j.ab.2017.06.014_bib9","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1007\/s00277-013-1777-2","article-title":"Molecular characterization of \u03b2-thalassemia in four communities in South Gujarat\u2013codon 30 (G\u2009\u2192\u2009A) a predominant mutation in the Kachhiya Patel community","volume":"92","author":"Bhukhanvala","year":"2013","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.ab.2017.06.014_bib10","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1365-2141.1991.tb04423.x","article-title":"The spectrum of \u03b2- thalassemia mutations on the Indian subcontinent: the basis for prenatal diagnosis","volume":"78","author":"Varawalla","year":"1991","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.ab.2017.06.014_bib11","series-title":"Genetic Atlas of Indian Tribes","first-page":"263","author":"Bhatia","year":"1986"},{"key":"10.1016\/j.ab.2017.06.014_bib12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1002\/(SICI)1096-8652(199706)55:2<104::AID-AJH9>3.0.CO;2-X","article-title":"Effect of \u03b1-thalassemia on sickle cell anemia linked to the Arab-Indian haplotype in India","volume":"55","author":"Mukherjee","year":"1997","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.ab.2017.06.014_bib13","first-page":"885","article-title":"Sickle cell syndromes in and around bardoli","volume":"42","author":"Iyer","year":"1994","journal-title":"J.\u00a0Assoc. Physicians India"},{"key":"10.1016\/j.ab.2017.06.014_bib14","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1093\/nar\/17.7.2503","article-title":"Analysis of any point mutation in DNA: the amplification refractory mutation system (ARMS)","volume":"17","author":"Newton","year":"1989","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ab.2017.06.014_bib15","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/pd.1970090906","article-title":"Prenatal diagnosis of beta thalassemia in Mediterranean populations by dot blot analysis with DNA amplification and allele specific oligonucleotide probes","volume":"9","author":"Ristaldi","year":"1989","journal-title":"Prenat. Diagn"},{"key":"10.1016\/j.ab.2017.06.014_bib16","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ymgme.2003.08.014","article-title":"Neonatal hemoglobinopathy screening: molecular genetic technologies","volume":"80","author":"Bhardwaj","year":"2003","journal-title":"Mol. Genet. Metab."},{"issue":"1","key":"10.1016\/j.ab.2017.06.014_bib17","first-page":"39","article-title":"Genetics of thalassemia in indian population","volume":"1","author":"Amrita","year":"2012","journal-title":"J.\u00a0Community Nutr. Health"},{"issue":"1","key":"10.1016\/j.ab.2017.06.014_bib18","first-page":"13","article-title":"Mutational spectrum of thalassemias in India","author":"Inusha","year":"2017","journal-title":"Indian J. Hum. Genetv"},{"issue":"4","key":"10.1016\/j.ab.2017.06.014_bib19","first-page":"28","article-title":"Beta thalassmia in India: current status and the challenges","volume":"6","author":"Kirti","year":"2014","journal-title":"Int. J. Pharm. Pharm. Sci."},{"key":"10.1016\/j.ab.2017.06.014_bib20","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/0140-6736(90)92338-I","article-title":"Rapid detection and prenatal diagnosis of b thalassemia. Studies in Indian and Cypriot population in the UK","volume":"336","author":"Old","year":"1990","journal-title":"Lancet"},{"issue":"31\u201332","key":"10.1016\/j.ab.2017.06.014_bib21","first-page":"532","article-title":"Hemoglobinopathies clinical manifestations, diagnosis, and treatment","volume":"108","author":"Kohne","year":"2011","journal-title":"Dtsch. Arztebl Int."},{"key":"10.1016\/j.ab.2017.06.014_bib22","doi-asserted-by":"crossref","first-page":"592","DOI":"10.2174\/156652408786241375","article-title":"Hemoglobinopathies worldwide: present and future","volume":"8","author":"Weatherall","year":"2008","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.ab.2017.06.014_bib23","series-title":"Current Protocol in Human Genetics","article-title":"Selection of a platform for mutation detection","author":"Joshi","year":"2008"}],"container-title":["Analytical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000326971730283X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000326971730283X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T21:20:56Z","timestamp":1757712056000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000326971730283X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":23,"alternative-id":["S000326971730283X"],"URL":"https:\/\/doi.org\/10.1016\/j.ab.2017.06.014","relation":{},"ISSN":["0003-2697"],"issn-type":[{"value":"0003-2697","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A multiplex ARMS PCR approach to detection of common \u03b2-globin gene mutations","name":"articletitle","label":"Article Title"},{"value":"Analytical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ab.2017.06.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}