{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T00:30:01Z","timestamp":1713659401320},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytical Biochemistry"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.ab.2024.115524","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T07:21:00Z","timestamp":1711696860000},"page":"115524","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of a back-titration assay to quantitate functional lympho-epithelial Kazal-type inhibitors (LEKTI) in skin samples"],"prefix":"10.1016","volume":"690","author":[{"given":"Dorival","family":"Martins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Aude","family":"Pinoteau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger","family":"Leger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ab.2024.115524_bib1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/ng1493","article-title":"Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity","volume":"37","author":"Descargues","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ab.2024.115524_bib2","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1084\/jem.20082242","article-title":"Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome","volume":"206","author":"Briot","year":"2009","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ab.2024.115524_bib3","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s40291-016-0243-y","article-title":"Netherton syndrome: a genotype-phenotype review","volume":"21","author":"Sarri","year":"2017","journal-title":"Mol. Diagn. Ther."},{"key":"10.1016\/j.ab.2024.115524_bib4","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1172\/JCI41440","article-title":"Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing","volume":"120","author":"Bonnart","year":"2010","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ab.2024.115524_bib5","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/75977","article-title":"Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome","volume":"25","author":"Chavanas","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ab.2024.115524_bib6","doi-asserted-by":"crossref","first-page":"3607","DOI":"10.1091\/mbc.e07-02-0124","article-title":"LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction","volume":"18","author":"Deraison","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ab.2024.115524_bib7","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/nrd4534","article-title":"Unleashing the therapeutic potential of human kallikrein-related serine proteases","volume":"14","author":"Prassas","year":"2015","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ab.2024.115524_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1005389","article-title":"KLK5 inactivation reverses cutaneous hallmarks of Netherton syndrome","volume":"11","author":"Furio","year":"2015","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ab.2024.115524_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pgen.1006566","article-title":"KLK5 and KLK7 ablation fully rescues lethality of Netherton syndrome-like phenotype","volume":"13","author":"Kasparek","year":"2017","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ab.2024.115524_bib11","article-title":"M10 bioanalytical method validation and study sample analysis","year":"2022","journal-title":"Guidance for Industry"},{"key":"10.1016\/j.ab.2024.115524_bib12","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1038\/sj.jid.5701153","article-title":"Correlation between SPINK5 gene mutations and clinical manifestations in Netherton syndrome patients","volume":"128","author":"Komatsu","year":"2008","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ab.2024.115524_bib13","doi-asserted-by":"crossref","first-page":"32174","DOI":"10.1074\/jbc.M109.091850","article-title":"Isolation of SPINK6 in human skin: selective inhibitor of kallikrein-related peptidases","volume":"285","author":"Meyer-Hoffert","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ab.2024.115524_bib14","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1038\/sj.jid.5700288","article-title":"Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome","volume":"126","author":"Hachem","year":"2006","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ab.2024.115524_bib15","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1074\/jbc.M607567200","article-title":"A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation","volume":"282","author":"Borgo\u00f1o","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ab.2024.115524_bib16","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1111\/j.1365-2133.2005.06834.x","article-title":"hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6","volume":"153","author":"Egelrud","year":"2005","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.ab.2024.115524_bib17","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/bjd.19760","article-title":"Tape strips in dermatology research","volume":"185","author":"Hughes","year":"2021","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.ab.2024.115524_bib18","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.jid.2021.01.004","article-title":"Research techniques made simple: stratum corneum tape stripping","volume":"141","author":"Keurentjes","year":"2021","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ab.2024.115524_bib19","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.1016\/j.jid.2021.01.029","article-title":"A potent and selective kallikrein-5 inhibitor delivers high pharmacological activity in skin from patients with Netherton syndrome","volume":"141","author":"Liddle","year":"2021","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ab.2024.115524_bib20","doi-asserted-by":"crossref","first-page":"31852","DOI":"10.1074\/jbc.M705190200","article-title":"Activation profiles and regulatory cascades of the human kallikrein-related peptidases","volume":"282","author":"Yoon","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ab.2024.115524_bib21","doi-asserted-by":"crossref","first-page":"4187","DOI":"10.1093\/hmg\/dds243","article-title":"The 420K LEKTI variant alters LEKTI proteolytic activation and results in protease deregulation: implications for atopic dermatitis","volume":"21","author":"Fortugno","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ab.2024.115524_bib22","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1038\/jid.2011.174","article-title":"Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis","volume":"131","author":"Fortugno","year":"2011","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ab.2024.115524_bib23","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1074\/mcp.M116.065706","article-title":"Protease-inhibitor interaction predictions: lessons on the complexity of protein\u2013protein interactions","volume":"16","author":"Fortelny","year":"2017","journal-title":"Mol. Cell. Proteomics"}],"container-title":["Analytical Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000326972400068X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000326972400068X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,20]],"date-time":"2024-04-20T08:00:09Z","timestamp":1713600009000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000326972400068X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":22,"alternative-id":["S000326972400068X"],"URL":"https:\/\/doi.org\/10.1016\/j.ab.2024.115524","relation":{},"ISSN":["0003-2697"],"issn-type":[{"value":"0003-2697","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of a back-titration assay to quantitate functional lympho-epithelial Kazal-type inhibitors (LEKTI) in skin samples","name":"articletitle","label":"Article Title"},{"value":"Analytical Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ab.2024.115524","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115524"}}