{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T22:34:50Z","timestamp":1791758090098,"version":"4.3.4"},"reference-count":48,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1016\/j.abb.2008.02.028","type":"journal-article","created":{"date-parts":[[2008,3,5]],"date-time":"2008-03-05T17:15:54Z","timestamp":1204737354000},"page":"117-123","source":"Crossref","is-referenced-by-count":144,"title":["The response of bone to mechanical loading and disuse: Fundamental principles and influences on osteoblast\/osteocyte homeostasis"],"prefix":"10.1016","volume":"473","author":[{"given":"Tim M.","family":"Skerry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.abb.2008.02.028_bib1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/342270a0","volume":"342","author":"Swartz","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.abb.2008.02.028_bib2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0021-9290(79)90073-3","volume":"12","author":"Currey","year":"1979","journal-title":"Journal of Biomechanics"},{"key":"10.1016\/j.abb.2008.02.028_bib3","doi-asserted-by":"crossref","first-page":"S68","DOI":"10.1007\/BF01673406","volume":"53","author":"Biewener","year":"1993","journal-title":"Calcified Tissue International"},{"key":"10.1016\/j.abb.2008.02.028_bib4","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/359726a0","volume":"359","author":"Swartz","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.abb.2008.02.028_bib5","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.jbiomech.2005.02.016","volume":"39","author":"Yan","year":"2006","journal-title":"Journal of Biomechanics"},{"key":"10.1016\/j.abb.2008.02.028_bib6","series-title":"A Clinico-Pathological Study of Racing Accidents in Horses","author":"Vaughn","year":"1975"},{"key":"10.1016\/j.abb.2008.02.028_bib7","doi-asserted-by":"crossref","first-page":"S443","DOI":"10.1002\/jbmr.5650100503","volume":"10","author":"Hillam","year":"1995","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.abb.2008.02.028_bib8","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/BF02556712","volume":"38","author":"Lanyon","year":"1986","journal-title":"Calcified Tissue International"},{"key":"10.1016\/j.abb.2008.02.028_bib9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/(SICI)1097-0185(199602)244:2<139::AID-AR1>3.0.CO;2-X","volume":"244","author":"Frost","year":"1996","journal-title":"Anatomical Record"},{"key":"10.1016\/j.abb.2008.02.028_bib10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF03327422","volume":"18","author":"Suominen","year":"2006","journal-title":"Aging Clinical and Experimental Research"},{"key":"10.1016\/j.abb.2008.02.028_bib11","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S8756-3282(02)00927-4","volume":"32","author":"Nevill","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.abb.2008.02.028_bib12","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s002239900117","volume":"59","author":"Karlsson","year":"1996","journal-title":"Calcified Tissue International"},{"key":"10.1016\/j.abb.2008.02.028_bib13","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/BF00302066","volume":"57","author":"Karlsson","year":"1995","journal-title":"Calcified Tissue International"},{"key":"10.1016\/j.abb.2008.02.028_bib14","first-page":"S184","volume":"14","author":"Karlsson","year":"1999","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.abb.2008.02.028_bib15","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S8756-3282(96)00387-0","volume":"20","author":"Skerry","year":"1997","journal-title":"Bone"},{"key":"10.1016\/j.abb.2008.02.028_bib16","first-page":"122","volume":"6","author":"Skerry","year":"2006","journal-title":"Journal of Musculoskeletal & Neuronal Interactions"},{"key":"10.1016\/j.abb.2008.02.028_bib17","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/jor.1100050217","volume":"5","author":"Rubin","year":"1987","journal-title":"Journal of Orthopaedic Research"},{"key":"10.1016\/j.abb.2008.02.028_bib18","doi-asserted-by":"crossref","first-page":"O6","DOI":"10.1359\/jbmr.1997.12.1.6","volume":"12","author":"Skerry","year":"1997","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.abb.2008.02.028_bib19","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1359\/jbmr.2002.17.8.1545","volume":"17","author":"Robling","year":"2002","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.abb.2008.02.028_bib20","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.bone.2006.05.017","volume":"39","author":"Kim","year":"2006","journal-title":"Bone"},{"key":"10.1016\/j.abb.2008.02.028_bib21","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1002\/jcb.20864","volume":"98","author":"Mehrotra","year":"2006","journal-title":"Journal of Cellular Biochemistry"},{"key":"10.1016\/j.abb.2008.02.028_bib22","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.jbiomech.2005.04.011","volume":"39","author":"Saunders","year":"2006","journal-title":"Journal of Biomechanics"},{"key":"10.1016\/j.abb.2008.02.028_bib23","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1359\/jbmr.2002.17.8.1452","volume":"17","author":"Rubin","year":"2002","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.abb.2008.02.028_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S8756-3282(97)00223-8","volume":"22","author":"Schiessl","year":"1998","journal-title":"Bone"},{"key":"10.1016\/j.abb.2008.02.028_bib25","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s00401-004-0825-3","volume":"107","author":"Garcia-Cabezas","year":"2004","journal-title":"Acta Neuropathologica"},{"key":"10.1016\/j.abb.2008.02.028_bib26","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1002\/ajmg.1320550416","volume":"55","author":"Chen","year":"1995","journal-title":"American Journal of Medical Genetics"},{"key":"10.1016\/j.abb.2008.02.028_bib27","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1203\/00006450-200301000-00005","volume":"53","author":"Miller","year":"2003","journal-title":"Pediatric Research"},{"key":"10.1016\/j.abb.2008.02.028_bib28","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1469-7580.2007.00698.x","volume":"210","author":"Gomez","year":"2007","journal-title":"Journal of Anatomy"},{"key":"10.1016\/j.abb.2008.02.028_bib29","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1046\/j.1365-2613.2003.00353.x","volume":"84","author":"Lamb","year":"2003","journal-title":"International Journal of Experimental Pathology"},{"key":"10.1016\/j.abb.2008.02.028_bib30","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0022-5193(88)80122-X","volume":"131","author":"Bertram","year":"1988","journal-title":"Journal of Theoretical Biology"},{"key":"10.1016\/j.abb.2008.02.028_bib31","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0021-9290(99)00210-9","volume":"33","author":"Fritton","year":"2000","journal-title":"Journal of Biomechanics"},{"key":"10.1016\/j.abb.2008.02.028_bib32","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/S1359-6446(01)01872-4","volume":"6","author":"Rubin","year":"2001","journal-title":"Drug Discovery Today"},{"key":"10.1016\/j.abb.2008.02.028_bib33","first-page":"165","author":"Rubin","year":"1994","journal-title":"Clinical Orthopaedics and Related Research"},{"key":"10.1016\/j.abb.2008.02.028_bib34","first-page":"S77","volume":"32","author":"Rubin","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.abb.2008.02.028_bib35","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1002\/jor.20258","volume":"24","author":"Chan","year":"2006","journal-title":"Journal of Orthopaedic Research"},{"key":"10.1016\/j.abb.2008.02.028_bib36","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0197-0186(94)00155-N","volume":"26","author":"Belluardo","year":"1995","journal-title":"Neurochemistry International"},{"key":"10.1016\/j.abb.2008.02.028_bib37","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/(SICI)1097-4652(199701)170:1<81::AID-JCP9>3.0.CO;2-H","volume":"170","author":"Rubin","year":"1997","journal-title":"Journal of Cellular Physiology"},{"key":"10.1016\/j.abb.2008.02.028_bib38","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1002\/jbmr.5650040519","volume":"4","author":"Skerry","year":"1989","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.abb.2008.02.028_bib39","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/BF02409482","volume":"33","author":"Doty","year":"1981","journal-title":"Calcified Tissue International"},{"key":"10.1016\/j.abb.2008.02.028_bib40","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/jcb.10109","volume":"85","author":"Heino","year":"2002","journal-title":"Journal of Cellular Biochemistry"},{"key":"10.1016\/j.abb.2008.02.028_bib41","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.ijfatigue.2006.06.011","volume":"29","author":"Kurata","year":"2007","journal-title":"International Journal of Fatigue"},{"key":"10.1016\/j.abb.2008.02.028_bib42","doi-asserted-by":"crossref","first-page":"C545","DOI":"10.1152\/ajpcell.00611.2005","volume":"292","author":"Taylor","year":"2007","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1016\/j.abb.2008.02.028_bib43","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.1016\/j.jbiomech.2007.02.015","volume":"40","author":"Vatsa","year":"2007","journal-title":"Journal of Biomechanics"},{"key":"10.1016\/j.abb.2008.02.028_bib44","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.1128\/MCB.02120-05","volume":"26","author":"Zhang","year":"2006","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.abb.2008.02.028_bib45","doi-asserted-by":"crossref","first-page":"C934","DOI":"10.1152\/ajpcell.00234.2002","volume":"284","author":"Noble","year":"2003","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1016\/j.abb.2008.02.028_bib46","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1016\/j.lfs.2004.04.048","volume":"75","author":"Kogianni","year":"2004","journal-title":"Life Sciences"},{"key":"10.1016\/j.abb.2008.02.028_bib47","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1007\/s00223-004-0048-6","volume":"76","author":"Maimoun","year":"2005","journal-title":"Calcified Tissue International"},{"key":"10.1016\/j.abb.2008.02.028_bib48","doi-asserted-by":"crossref","first-page":"79S","DOI":"10.1016\/S8756-3282(98)00020-9","volume":"22","author":"Miyamoto","year":"1998","journal-title":"Bone"}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986108001021?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986108001021?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T06:05:52Z","timestamp":1708668352000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986108001021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["S0003986108001021"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2008.02.028","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}