{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:27:43Z","timestamp":1792798063312,"version":"4.5.0"},"reference-count":259,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,8,16]],"date-time":"2019-08-16T00:00:00Z","timestamp":1565913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.abb.2019.108073","type":"journal-article","created":{"date-parts":[[2019,8,16]],"date-time":"2019-08-16T01:47:13Z","timestamp":1565920033000},"page":"108073","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":139,"special_numbering":"C","title":["HO-1 overexpression and underexpression: Clinical implications"],"prefix":"10.1016","volume":"673","author":[{"given":"George S.","family":"Drummond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Baum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menachem","family":"Greenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nader G.","family":"Abraham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nm0196-87","article-title":"Heme oxygenase: a novel target for the modulation of the inflammatory response","volume":"2","author":"Willis","year":"1996","journal-title":"Nat. Med."},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib2","doi-asserted-by":"crossref","first-page":"5181","DOI":"10.4049\/jimmunol.174.9.5181","article-title":"An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells","volume":"174","author":"Brusko","year":"2005","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib3","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1152\/physrev.00011.2005","article-title":"Heme oxygenase-1\/carbon monoxide: from basic science to therapeutic applications","volume":"86","author":"Ryter","year":"2006","journal-title":"Physiol. Rev."},{"issue":"8","key":"10.1016\/j.abb.2019.108073_bib4","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S1471-4906(03)00181-9","article-title":"Heme oxygenase-1: unleashing the protective properties of heme","volume":"24","author":"Otterbein","year":"2003","journal-title":"Trends Immunol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib5","doi-asserted-by":"crossref","first-page":"154","DOI":"10.2353\/ajpath.2008.070963","article-title":"Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells","volume":"173","author":"George","year":"2008","journal-title":"Am. J. Pathol."},{"issue":"15","key":"10.1016\/j.abb.2019.108073_bib6","doi-asserted-by":"crossref","first-page":"8798","DOI":"10.1073\/pnas.161272598","article-title":"Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia","volume":"98","author":"Minamino","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib7","doi-asserted-by":"crossref","first-page":"3553","DOI":"10.4049\/jimmunol.172.6.3553","article-title":"Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation","volume":"172","author":"Soares","year":"2004","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib8","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1172\/JCI11218","article-title":"Carbon monoxide of vascular origin attenuates the sensitivity of renal arterial vessels to vasoconstrictors","volume":"107","author":"Kaide","year":"2001","journal-title":"J. Clin. Investig."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib9","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1161\/01.HYP.0000135658.57547.bb","article-title":"Vascular CO counterbalances the sensitizing influence of 20-HETE on agonist-induced vasoconstriction","volume":"44","author":"Kaide","year":"2004","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib10","doi-asserted-by":"crossref","first-page":"H1999","DOI":"10.1152\/ajpheart.00082.2006","article-title":"Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase","volume":"291","author":"Sacerdoti","year":"2006","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib11","doi-asserted-by":"crossref","first-page":"L1117","DOI":"10.1152\/ajplung.00365.2001","article-title":"Modulation of cGMP by human HO-1 retrovirus gene transfer in pulmonary microvessel endothelial cells","volume":"283","author":"Abraham","year":"2002","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib12","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1161\/HYPERTENSIONAHA.114.03884","article-title":"CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype","volume":"64","author":"Abraham","year":"2014","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib13","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1634\/stemcells.2008-0800","article-title":"Diabetes impairs the vascular recruitment of normal stem cells by oxidant damage; reversed by increases in pAMPK, heme oxygenase-1 and adiponectin","volume":"27","author":"Sambuceti","year":"2009","journal-title":"Stem Cells"},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib14","doi-asserted-by":"crossref","first-page":"L1029","DOI":"10.1152\/ajplung.2000.279.6.L1029","article-title":"Heme oxygenase: colors of defense against cellular stress","volume":"279","author":"Otterbein","year":"2000","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib15","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.2174\/13816128113199990559","article-title":"A critical and comprehensive insight on heme oxygenase and related products including carbon monoxide, bilirubin, biliverdin and ferritin in type-1 and type-2 diabetes","volume":"20","author":"Mishra","year":"2014","journal-title":"Curr. Pharmaceut. Des."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib16","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1161\/CIRCULATIONAHA.107.698316","article-title":"Heme oxygenase-1 and carbon monoxide in vascular pathobiology: focus on angiogenesis","volume":"117","author":"Dulak","year":"2008","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.abb.2019.108073_bib17","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.3390\/ijms9122388","article-title":"Upregulation of heme oxygenase-1 combined with increased adiponectin lowers blood pressure in diabetic spontaneously hypertensive rats through a reduction in endothelial cell dysfunction, apoptosis and oxidative stress","volume":"9","author":"Cao","year":"2008","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib18","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1089\/hum.2010.059","article-title":"Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension","volume":"22","author":"Cao","year":"2011","journal-title":"Hum. Gene Ther."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib19","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1161\/HYPERTENSIONAHA.112.193805","article-title":"Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet","volume":"60","author":"Cao","year":"2012","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib20","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1161\/HYPERTENSIONAHA.110.151423","article-title":"Adipocyte heme oxygenase-1 induction attenuates metabolic syndrome in both male and female obese mice","volume":"56","author":"Burgess","year":"2010","journal-title":"Hypertension"},{"issue":"23","key":"10.1016\/j.abb.2019.108073_bib21","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1161\/CIRCULATIONAHA.104.517102","article-title":"D-4F induces heme oxygenase-1 and extracellular superoxide dismutase, decreases endothelial cell sloughing, and improves vascular reactivity in rat model of diabetes","volume":"111","author":"Kruger","year":"2005","journal-title":"Circulation"},{"issue":"40","key":"10.1016\/j.abb.2019.108073_bib22","doi-asserted-by":"crossref","first-page":"33720","DOI":"10.1074\/jbc.M112.385542","article-title":"The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-regulated kinase (ERK)\/NRF2 signaling pathway and cytokine release","volume":"287","author":"Cai","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib23","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1096\/fj.05-4435com","article-title":"Heme oxygenase-1 (HO-1) inhibits postmyocardial infarct remodeling and restores ventricular function","volume":"20","author":"Liu","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.abb.2019.108073_bib24","doi-asserted-by":"crossref","first-page":"18148","DOI":"10.1016\/S0021-9258(19)37165-0","article-title":"Ferritin: a cytoprotective antioxidant strategm of endothelium","volume":"267","author":"Balla","year":"1992","journal-title":"J. Biol. Chem."},{"issue":"10","key":"10.1016\/j.abb.2019.108073_bib25","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1016\/j.humpath.2013.05.008","article-title":"Association between hemoglobin scavenger receptor and heme oxygenase-1-related anti-inflammatory mediators in human coronary stable and unstable plaques","volume":"44","author":"Yunoki","year":"2013","journal-title":"Hum. Pathol."},{"issue":"11","key":"10.1016\/j.abb.2019.108073_bib26","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1089\/ars.2013.5666","article-title":"Coupling heme and iron metabolism via ferritin H chain","volume":"20","author":"Gozzelino","year":"2014","journal-title":"Antioxidants Redox Signal."},{"issue":"7","key":"10.1016\/j.abb.2019.108073_bib27","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1016\/S0041-1345(02)03506-6","article-title":"TNF-alpha-mediated cell death is attenuated by retrovirus delivery of human heme oxygenase-1 gene into human microvessel endothelial cells","volume":"34","author":"Kushida","year":"2002","journal-title":"Transplant. Proc."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib28","doi-asserted-by":"crossref","first-page":"C897","DOI":"10.1152\/ajpcell.00032.2006","article-title":"HO-2 provides endogenous protection against oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells","volume":"291","author":"Basuroy","year":"2006","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib29","doi-asserted-by":"crossref","first-page":"F863","DOI":"10.1152\/ajprenal.00385.2002","article-title":"Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade","volume":"284","author":"Agarwal","year":"2003","journal-title":"Am. J. Physiol. Renal. Physiol."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib30","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1177\/15353702-0322805-31","article-title":"Heme oxygenase-1 gene expression attenuates angiotensin II-mediated DNA damage in endothelial cells","volume":"228","author":"Mazza","year":"2003","journal-title":"Exp. Biol. Med."},{"issue":"1 Pt 1","key":"10.1016\/j.abb.2019.108073_bib31","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0092-8674(81)90039-8","article-title":"Hemin enhances the differentiation of mouse 3T3 cells to adipocytes","volume":"26","author":"Chen","year":"1981","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib32","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0268-960X(91)90004-V","article-title":"Molecular regulation--biological role of heme in hematopoiesis","volume":"5","author":"Abraham","year":"1991","journal-title":"Blood Rev."},{"issue":"5\u20136","key":"10.1016\/j.abb.2019.108073_bib33","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0049-3848(03)00417-1","article-title":"Heme oxygenase attenuated angiotensin II-mediated increase in cyclooxygenase activity and decreased isoprostane F2alpha in endothelial cells","volume":"110","author":"Abraham","year":"2003","journal-title":"Thromb. Res."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib34","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1111\/j.1523-1755.2004.00562.x","article-title":"Expression of human heme oxygenase-1 in the thick ascending limb attenuates angiotensin II-mediated increase in oxidative injury","volume":"65","author":"Quan","year":"2004","journal-title":"Kidney Int."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib35","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1161\/01.hyp.0000126287.62060.e6","article-title":"Heme oxygenase-1 gene expression modulates angiotensin II-induced increase in blood pressure","volume":"43","author":"Yang","year":"2004","journal-title":"Hypertension"},{"key":"10.1016\/j.abb.2019.108073_bib36","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3389\/fphar.2013.00050","article-title":"Mesobiliverdin IXalpha enhances rat pancreatic islet yield and function","volume":"4","author":"Ito","year":"2013","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib37","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1210\/en.2013-1667","article-title":"Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation","volume":"155","author":"Dong","year":"2014","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib38","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1161\/01.RES.0000091828.36599.34","article-title":"Heme oxygenase-1 attenuates glucose-mediated cell growth arrest and apoptosis in human microvessel endothelial cells","volume":"93","author":"Abraham","year":"2003","journal-title":"Circ. Res."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib39","doi-asserted-by":"crossref","first-page":"H2468","DOI":"10.1152\/ajpheart.01187.2003","article-title":"Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes","volume":"287","author":"Abraham","year":"2004","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"23","key":"10.1016\/j.abb.2019.108073_bib40","doi-asserted-by":"crossref","first-page":"15687","DOI":"10.1074\/jbc.M510595200","article-title":"Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes","volume":"281","author":"Di Noia","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.abb.2019.108073_bib41","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1096\/fj.05-4204fje","article-title":"HO-1 is located in liver mitochondria and modulates mitochondrial heme content and metabolism","volume":"8","author":"Converso","year":"2006","journal-title":"FASEB J."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib42","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/ki.2012.102","article-title":"In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice","volume":"82","author":"Kim","year":"2012","journal-title":"Kidney Int."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib43","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/89068","article-title":"Heme oxygenase-1 protects against vascular constriction and proliferation","volume":"7","author":"Duckers","year":"2001","journal-title":"Nat. Med."},{"key":"10.1016\/j.abb.2019.108073_bib44","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1161\/01.RES.80.4.557","article-title":"Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth cells","volume":"80","author":"Durante","year":"1997","journal-title":"Circ. Res."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib45","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0006-291X(02)02054-5","article-title":"Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression","volume":"296","author":"Li Volti","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"20","key":"10.1016\/j.abb.2019.108073_bib46","doi-asserted-by":"crossref","first-page":"7251","DOI":"10.1073\/pnas.0502407102","article-title":"Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway","volume":"102","author":"Chen","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib47","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1161\/hc0102.101369","article-title":"Adenovirus-mediated heme oxygenase-1 gene expression stimulates apoptosis in vascular smooth muscle cells","volume":"105","author":"Liu","year":"2002","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib48","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/S0008-6363(02)00410-8","article-title":"Carbon monoxide inhibits apoptosis in vascular smooth muscle cells","volume":"55","author":"Liu","year":"2002","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.abb.2019.108073_bib49","doi-asserted-by":"crossref","first-page":"32804","DOI":"10.1074\/jbc.272.52.32804","article-title":"Carbon monoxide controls the proliferation of hypoxic smooth muscle cells","volume":"272","author":"Morita","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib50","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1038\/oby.2011.365","article-title":"High-fat diet exacerbates renal dysfunction in SHR: reversal by induction of HO-1-adiponectin axis","volume":"20","author":"Cao","year":"2012","journal-title":"Obesity"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib51","doi-asserted-by":"crossref","first-page":"H962","DOI":"10.1152\/ajpheart.01218.2003","article-title":"Interaction between endothelial heme oxygenase-2 and endothelin-1 in altered aortic reactivity after hypoxia in rats","volume":"288","author":"Govindaraju","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib52","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.ejphar.2003.12.026","article-title":"Carbon monoxide inhibits endothelin-1 release by human pulmonary artery smooth muscle cells","volume":"486","author":"Stanford","year":"2004","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib53","doi-asserted-by":"crossref","first-page":"H137","DOI":"10.1152\/ajpheart.00678.2002","article-title":"CO modulates pulmonary vascular response to acute hypoxia: relation to endothelin","volume":"286","author":"Zhang","year":"2004","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib54","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.tips.2008.12.003","article-title":"Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubin","volume":"30","author":"Kapitulnik","year":"2009","journal-title":"Trends Pharmacol. Sci."},{"issue":"11","key":"10.1016\/j.abb.2019.108073_bib55","doi-asserted-by":"crossref","first-page":"9226","DOI":"10.1074\/jbc.M108239200","article-title":"Human biliverdin reductase is a leucine zipper-like DNA-binding protein and functions in transcriptional activation of heme oxygenase-1 by oxidative stress","volume":"277","author":"Ahmad","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.abb.2019.108073_bib56","first-page":"741","article-title":"The light reversible carbon monoxide inhibition of the steroid C21-hydroxylase system of the adrenal cortex","volume":"338","author":"Estabrook","year":"1963","journal-title":"Biochem. Z."},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib57","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1021\/bi00759a029","article-title":"Enzymatic degradation of heme. Oxygenative cleavage requiring cytochrome P-450","volume":"11","author":"Tenhunen","year":"1972","journal-title":"Biochemistry"},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib58","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.freeradbiomed.2007.08.012","article-title":"Carbon monoxide donors or heme oxygenase-1 (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death","volume":"44","author":"Zabalgoitia","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.abb.2019.108073_bib59","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1124\/pr.107.07104","article-title":"Pharmacological and clinical aspects of heme oxygenase","volume":"60","author":"Abraham","year":"2008","journal-title":"Pharmacol. Rev."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib60","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/geronj\/38.1.13","article-title":"Erythroid colony development as a function of age: the role of marrow cellular heme","volume":"38","author":"Abraham","year":"1983","journal-title":"J. Gerontol."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib61","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1182\/blood.V78.6.1461.1461","article-title":"Modulation of erythropoiesis by novel human bone marrow cytochrome P450-dependent metabolites of arachidonic acid","volume":"78","author":"Abraham","year":"1991","journal-title":"Blood"},{"key":"10.1016\/j.abb.2019.108073_bib62","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000154819","article-title":"The biological significance and physiological role of heme oxygenase","volume":"6","author":"Abraham","year":"1996","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.abb.2019.108073_bib63","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1172\/JCI112309","article-title":"Control of heme metabolism with synthetic metalloporphyrins","volume":"77","author":"Kappas","year":"1986","journal-title":"J. Clin. Investig."},{"issue":"1 Pt 1","key":"10.1016\/j.abb.2019.108073_bib64","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1542\/peds.113.1.119","article-title":"A method for interdicting the development of severe jaundice in newborns by inhibiting the production of bilirubin","volume":"113","author":"Kappas","year":"2004","journal-title":"Pediatrics"},{"issue":"4566","key":"10.1016\/j.abb.2019.108073_bib65","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1126\/science.6896768","article-title":"Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal model","volume":"217","author":"Drummond","year":"1982","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib66","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/j.1432-1033.1990.tb19263.x","article-title":"Regulation of heme oxygenase gene expression by cobalt in rat liver and kidney","volume":"192","author":"Lin","year":"1990","journal-title":"Eur. J. Biochem."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib67","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1124\/jpet.106.107482","article-title":"Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects","volume":"319","author":"Kruger","year":"2006","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib68","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1471-2210-4-26","article-title":"Peroxynitrite-mediated inactivation of heme oxygenases","volume":"4","author":"Kinobe","year":"2004","journal-title":"BMC Pharmacol."},{"key":"10.1016\/j.abb.2019.108073_bib69","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.vph.2015.02.011","article-title":"HIF-regulated HO-1 gene transfer improves the post-ischemic limb recovery and diminishes TLR-triggered immune responses - effects modified by concomitant VEGF overexpression","volume":"71","author":"Jazwa","year":"2015","journal-title":"Vascul. Vasc. Pharmacol."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib70","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1007\/s00395-011-0208-6","article-title":"Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences","volume":"106","author":"Li","year":"2011","journal-title":"Basic Res. Cardiol."},{"issue":"10","key":"10.1016\/j.abb.2019.108073_bib71","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1016\/j.transproceed.2007.03.114","article-title":"Adenovirus-mediated heme oxygenase transfer inhibits graft arteriosclerosis in rat aortic transplants","volume":"39","author":"Du","year":"2007","journal-title":"Transplant. Proc."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib72","doi-asserted-by":"crossref","first-page":"H48","DOI":"10.1152\/ajpheart.00741.2006","article-title":"Preemptive heme oxygenase-1 gene delivery reveals reduced mortality and preservation of left ventricular function 1 yr after acute myocardial infarction","volume":"293","author":"Liu","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib73","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1159\/000374011","article-title":"CYP2J2 and EETs protect against lung ischemia\/reperfusion injury via anti-inflammatory effects in vivo and in vitro","volume":"35","author":"Chen","year":"2015","journal-title":"Cell. Physiol. Biochem."},{"issue":"4792","key":"10.1016\/j.abb.2019.108073_bib74","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1126\/science.3029864","article-title":"Bilirubin is an antioxidant of possible physiological importance","volume":"235","author":"Stocker","year":"1987","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib75","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1161\/01.ATV.16.2.250","article-title":"Higher serum bilirubin is associated with decreased risk for early familial coronary artery disease","volume":"16","author":"Hopkins","year":"1996","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.abb.2019.108073_bib76","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1126\/science.7678352","article-title":"Carbon monoxide: a putative neural messenger","volume":"259","author":"Verma","year":"1993","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib77","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1161\/01.ATV.0000066132.32063.F2","article-title":"Role of JNK, p38, and ERK in platelet-derived growth factor-induced vascular proliferation, migration, and gene expression","volume":"23","author":"Zhan","year":"2003","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.abb.2019.108073_bib78","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1146\/annurev.pharmtox.46.120604.141053","article-title":"CO as a cellular signaling molecule","volume":"46","author":"Kim","year":"2006","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib79","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1542\/peds.69.4.481","article-title":"Unbound bilirubin and kernicterus in low-birth-weight infants","volume":"69","author":"Cashore","year":"1982","journal-title":"Pediatrics"},{"issue":"5 Pt 1","key":"10.1016\/j.abb.2019.108073_bib80","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1542\/peds.89.5.809","article-title":"Evaluation and treatment of jaundice in the term newborn: a kinder, gentler approach","volume":"89","author":"Newman","year":"1992","journal-title":"Pediatrics"},{"key":"10.1016\/j.abb.2019.108073_bib81","doi-asserted-by":"crossref","first-page":"6865","DOI":"10.1021\/ja00388a103","article-title":"Phototherapy for neonatal jaundice: configurational isomers of bilirubin","volume":"104","author":"McDonagh","year":"1982","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.abb.2019.108073_bib82","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.chiabu.2018.03.017","article-title":"A pilot study demonstrating the efficacy of transcutaneous bilirubin meters to quantitatively differentiate contusions from Congenital Dermal Melanocytosis","volume":"80","author":"Abdy","year":"2018","journal-title":"Child Abuse Negl."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib83","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1172\/JCI112398","article-title":"Sn-protoporphyrin inhibition of fetal and neonatal brain heme oxygenase. Transplacental passage of the metalloporphyrin and prenatal suppression of hyperbilirubinemia in the newborn animal","volume":"77","author":"Drummond","year":"1986","journal-title":"J. Clin. Investig."},{"issue":"14","key":"10.1016\/j.abb.2019.108073_bib84","doi-asserted-by":"crossref","first-page":"4437","DOI":"10.1021\/jm0511435","article-title":"Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors","volume":"49","author":"Vlahakis","year":"2006","journal-title":"J. Med. Chem."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib85","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/hep.1840080331","article-title":"Sn-protoporphyrin lowers serum bilirubin levels, decreases biliary bilirubin output, enhances biliary heme excretion and potently inhibits hepatic heme oxygenase activity in normal human subjects","volume":"8","author":"Berglund","year":"1988","journal-title":"Hepatology"},{"issue":"8","key":"10.1016\/j.abb.2019.108073_bib86","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1136\/gut.31.8.899","article-title":"Studies with the haeme oxygenase inhibitor Sn-protoporphyrin in patients with primary biliary cirrhosis and idiopathic haemochromatosis","volume":"31","author":"Berglund","year":"1990","journal-title":"Gut"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib87","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1542\/peds.89.2.175","article-title":"Suppression of bilirubin production in the Crigler-Najjar type I syndrome: studies with the heme oxygenase inhibitor tin-mesoporphyrin [see comments]","volume":"89","author":"Galbraith","year":"1992","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib88","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1542\/peds.84.4.728","article-title":"Tin-protoporphyrin in the management of children with Crigler-Najjar disease","volume":"84","author":"Rubaltelli","year":"1989","journal-title":"Pediatrics"},{"key":"10.1016\/j.abb.2019.108073_bib89","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/peds.93.1.1","article-title":"Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin","volume":"93","author":"Valaes","year":"1994","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib90","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1542\/peds.95.4.468","article-title":"Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns","volume":"95","author":"Kappas","year":"1995","journal-title":"Pediatrics"},{"issue":"Suppl 1","key":"10.1016\/j.abb.2019.108073_bib91","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1038\/sj.jp.7210655","article-title":"Treatment of hyperbilirubinemia pharmacologic approach SnMP(tin-mesoporphyrin)","volume":"21","author":"Martinez","year":"2001","journal-title":"J. Perinatol."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib92","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1542\/peds.101.5.e1","article-title":"Control of hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns using an inhibitor of bilirubin production, Sn-mesoporphyrin","volume":"101","author":"Valaes","year":"1998","journal-title":"Pediatrics"},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib93","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.siny.2009.11.004","article-title":"Metalloporphyrins in the management of neonatal hyperbilirubinemia","volume":"15","author":"Stevenson","year":"2010","journal-title":"Semin. Fetal Neonatal Med."},{"key":"10.1016\/j.abb.2019.108073_bib94","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3389\/fphar.2012.00068","article-title":"Metalloporphyrins - an update","volume":"3","author":"Schulz","year":"2012","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib95","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1073\/pnas.82.3.896","article-title":"The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin","volume":"82","author":"Kappas","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib96","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/0003-9861(87)90294-3","article-title":"Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn- mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism","volume":"255","author":"Drummond","year":"1987","journal-title":"Arch. Biochem. Biophys."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib97","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1172\/JCI111727","article-title":"Studies on the mechanism of Sn-protoporphyrin suppression of hyperbilirubinemia. Inhibition of heme oxidation and bilirubin production","volume":"75","author":"Simionatto","year":"1985","journal-title":"J. Clin. Investig."},{"issue":"8","key":"10.1016\/j.abb.2019.108073_bib98","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1073\/pnas.84.8.2464","article-title":"Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver","volume":"84","author":"Sardana","year":"1987","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"19","key":"10.1016\/j.abb.2019.108073_bib99","doi-asserted-by":"crossref","first-page":"7653","DOI":"10.1073\/pnas.86.19.7653","article-title":"Regulation of food intake and body weight by cobalt porphyrins in animals","volume":"86","author":"Galbraith","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"8761","key":"10.1016\/j.abb.2019.108073_bib100","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0140-6736(91)90411-H","article-title":"Haem-arginate plus tin-protoporphyrin for acute hepatic porphyria","volume":"338","author":"Dover","year":"1991","journal-title":"Lancet"},{"issue":"19","key":"10.1016\/j.abb.2019.108073_bib101","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.120596","article-title":"Myeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injury","volume":"3","author":"Zhang","year":"2018","journal-title":"JCI. Insight"},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib102","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1016\/j.jhep.2017.08.010","article-title":"Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury","volume":"67","author":"Nakamura","year":"2017","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib103","doi-asserted-by":"crossref","first-page":"14019","DOI":"10.1038\/s41598-018-32411-4","article-title":"Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression","volume":"8","author":"Li","year":"2018","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib104","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.yexcr.2019.04.029","article-title":"Epoxyeicosatrienoic intervention improves NAFLD in leptin receptor deficient mice by an increase in PGC1alpha-HO-1-PGC1alpha-mitochondrial signaling","volume":"380","author":"Raffaele","year":"2019","journal-title":"Exp. Cell Res."},{"issue":"3 Pt 2","key":"10.1016\/j.abb.2019.108073_bib105","first-page":"625","article-title":"The kidney, hypertension, and obesity","volume":"41","author":"Hall","year":"2003","journal-title":"Hypertension"},{"issue":"13","key":"10.1016\/j.abb.2019.108073_bib106","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1001\/jama.295.13.1549","article-title":"Prevalence of overweight and obesity in the United States, 1999-2004","volume":"295","author":"Ogden","year":"2006","journal-title":"J. Am. Med. Assoc."},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib107","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.2337\/db06-1656","article-title":"Visceral fat adipokine secretion is associated with systemic inflammation in obese humans","volume":"56","author":"Fontana","year":"2007","journal-title":"Diabetes"},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib108","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.2337\/db07-1764","article-title":"Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance","volume":"57","author":"Li","year":"2008","journal-title":"Diabetes"},{"issue":"51","key":"10.1016\/j.abb.2019.108073_bib109","doi-asserted-by":"crossref","first-page":"12345","DOI":"10.1021\/bi9015555","article-title":"Disulfide-dependent self-assembly of adiponectin octadecamers from trimers and presence of stable octadecameric adiponectin lacking disulfide bonds in vitro","volume":"48","author":"Briggs","year":"2009","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib110","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1161\/HYPERTENSIONAHA.107.099424","article-title":"Adiponectin, cardiovascular function, and hypertension","volume":"51","author":"Wang","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.abb.2019.108073_bib111","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1042\/CS20090395","article-title":"Obesity is the major contributor to vascular dysfunction and inflammation in high fat diet hypertensive rats","volume":"118","author":"Elmarakby","year":"2010","journal-title":"Clin. Sci. (Lond.)"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib112","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1161\/01.HYP.0000090123.55365.BA","article-title":"Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension","volume":"42","author":"Wang","year":"2003","journal-title":"Hypertension"},{"issue":"7","key":"10.1016\/j.abb.2019.108073_bib113","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.1210\/en.2009-0800","article-title":"Regulation of adipogenesis by natural and synthetic REV-ERB ligands","volume":"151","author":"Kumar","year":"2010","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib114","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s11906-008-0019-9","article-title":"Local adipose tissue renin-angiotensin system","volume":"10","author":"Cassis","year":"2008","journal-title":"Curr. Hypertens. Rep."},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib115","doi-asserted-by":"crossref","first-page":"R943","DOI":"10.1152\/ajpregu.00265.2004","article-title":"Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension","volume":"287","author":"Boustany","year":"2004","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib116","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1074\/jbc.M108921200","article-title":"Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response","volume":"277","author":"Chang","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"Pt 3","key":"10.1016\/j.abb.2019.108073_bib117","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1042\/bj20021731","article-title":"Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain","volume":"371","author":"Chang","year":"2003","journal-title":"Biochem. J."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib118","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.bbrc.2004.01.086","article-title":"Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats","volume":"315","author":"Quan","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib119","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/oby.22354","article-title":"Oxidized HDL, adipokines, and endothelial dysfunction: a potential biomarker profile for cardiovascular risk in women with obesity","volume":"27","author":"Peterson","year":"2019","journal-title":"Obesity"},{"key":"10.1016\/j.abb.2019.108073_bib120","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/3484107","article-title":"Development of NASH in obese mice is confounded by adipose tissue increase in inflammatory NOV and oxidative stress","volume":"2018","author":"Sacerdoti","year":"2018","journal-title":"Int. J. Hepatol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib121","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/ijo.2013.116","article-title":"PPAR-delta binding to heme oxygenase 1 promoter prevents angiotensin II induced adipocyte dysfunction in goldblatt hypertensive rats","volume":"38","author":"Sodhi","year":"2013","journal-title":"Int. J. Obes."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib122","doi-asserted-by":"crossref","first-page":"412","DOI":"10.2174\/138161208783597371","article-title":"Heme oxygenase: a target gene for anti-diabetic and obesity","volume":"14","author":"Abraham","year":"2008","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.abb.2019.108073_bib123","article-title":"Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity","volume":"2010","author":"Ndisang","year":"2010","journal-title":"Mediators. Mediat. Inflamm."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib124","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1002\/jcb.24061","article-title":"Heme induced oxidative stress attenuates sirtuin1 and enhances adipogenesis in mesenchymal stem cells and mouse pre-adipocytes","volume":"113","author":"Puri","year":"2012","journal-title":"J. Cell. Biochem."},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib125","first-page":"905","article-title":"Hemin stimulation of hemopoiesis in murine long-term bone marrow culture","volume":"19","author":"Chertkov","year":"1991","journal-title":"Exp. Hematol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib126","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/ajh.2830440307","article-title":"Synergistic effect of heme and IL-1 on hematopoietic stromal regeneration after radiation","volume":"44","author":"Lutton","year":"1993","journal-title":"Am. J. Hematol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib127","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/s00774-009-0134-y","article-title":"Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation","volume":"28","author":"Barbagallo","year":"2010","journal-title":"J. Bone Miner. Metab."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib128","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.bone.2009.10.012","article-title":"HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage","volume":"46","author":"Vanella","year":"2010","journal-title":"Bone"},{"issue":"1\u20132","key":"10.1016\/j.abb.2019.108073_bib129","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1159\/000337591","article-title":"Heme oxygenase (HO-1) rescue of adipocyte dysfunction in HO-2 deficient mice via recruitment of epoxyeicosatrienoic acids (EETs) and adiponectin","volume":"29","author":"Burgess","year":"2012","journal-title":"Cell. Physiol. Biochem."},{"issue":"12","key":"10.1016\/j.abb.2019.108073_bib130","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1089\/scd.2010.0098","article-title":"Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARgamma","volume":"19","author":"Kim","year":"2010","journal-title":"Stem Cells Dev."},{"issue":"1\u20134","key":"10.1016\/j.abb.2019.108073_bib131","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.prostaglandins.2011.07.005","article-title":"Crosstalk between EET and HO-1 downregulates Bach1 and adipogenic marker expression in mesenchymal stem cell derived adipocytes","volume":"96","author":"Vanella","year":"2011","journal-title":"Prostaglandins Other Lipid Mediat."},{"issue":"6 Pt 2","key":"10.1016\/j.abb.2019.108073_bib132","first-page":"R1388","article-title":"Regulation of food intake and body weight in rats by the synthetic heme analogue cobalt protoporphyrin","volume":"261","author":"Galbraith","year":"1991","journal-title":"Am. J. Physiol."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib133","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1161\/ATVBAHA.107.142638","article-title":"Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors","volume":"27","author":"Kronke","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"8","key":"10.1016\/j.abb.2019.108073_bib134","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1194\/jlr.M800046-JLR200","article-title":"L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice","volume":"49","author":"Peterson","year":"2008","journal-title":"J. Lipid Res."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib135","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1161\/HYPERTENSIONAHA.108.124701","article-title":"Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats","volume":"53","author":"Nicolai","year":"2009","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib136","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/scrt176","article-title":"Increased heme-oxygenase 1 expression decreases adipocyte differentiation and lipid accumulation in mesenchymal stem cells via upregulation of the canonical Wnt signaling cascade","volume":"4","author":"Vanella","year":"2013","journal-title":"Stem Cell Res. Ther."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib137","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/scrt176","article-title":"Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade","volume":"4","author":"Vanella","year":"2013","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.abb.2019.108073_bib138","series-title":"Oxidized HDL Is a Potent Inducer of Adipogenesis and Causes Activation of the Ang-II and 20-HETE Systems in Human Obese Females","author":"Peterson","year":"2016"},{"key":"10.1016\/j.abb.2019.108073_bib139","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/957235","article-title":"Induction of hemeoxygenase-1 reduces renal oxidative stress and inflammation in diabetic spontaneously hypertensive rats","volume":"2012","author":"Elmarakby","year":"2012","journal-title":"Int. J. Hypertens."},{"issue":"7","key":"10.1016\/j.abb.2019.108073_bib140","doi-asserted-by":"crossref","first-page":"F791","DOI":"10.1152\/ajprenal.00472.2011","article-title":"Induction of hemeoxygenase-1 reduces glomerular injury and apoptosis in diabetic spontaneously hypertensive rats","volume":"302","author":"Elmarakby","year":"2012","journal-title":"Am. J. Physiol. Renal. Physiol."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib141","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.urology.2007.11.123","article-title":"Cobalt protoporphyrin attenuates rat obstructive nephropathy: role of cellular infiltration","volume":"72","author":"Iwai","year":"2008","journal-title":"Urology"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib142","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/j.1743-6109.2006.00211.x","article-title":"Increased intracavernosal pressure response in hypertensive rats after chronic hemin treatment","volume":"3","author":"Shamloul","year":"2006","journal-title":"J. Sex. Med."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib143","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0128648","article-title":"Fructose mediated non-alcoholic fatty liver is attenuated by HO-1-SIRT1 module in murine hepatocytes and mice fed a high fructose diet","volume":"10","author":"Sodhi","year":"2015","journal-title":"PLoS One"},{"issue":"3\u20134","key":"10.1016\/j.abb.2019.108073_bib144","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.prostaglandins.2011.12.004","article-title":"EET agonist prevents adiposity and vascular dysfunction in rats fed a high fat diet via a decrease in Bach 1 and an increase in HO-1 levels","volume":"98","author":"Sodhi","year":"2012","journal-title":"Prostagl. other Lipid Mediat."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib145","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00795-018-0205-z","article-title":"Protective role of heme oxygenase-1 in fatty liver ischemia-reperfusion injury","volume":"52","author":"Li","year":"2018","journal-title":"Med. Mol. Morphol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib146","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3164\/jcbn.18-35","article-title":"5-Aminolevulinic acid with ferrous iron improves early renal damage and hepatic steatosis in high fat diet-induced obese mice","volume":"64","author":"Kamiya","year":"2019","journal-title":"J. Clin. Biochem. Nutr."},{"key":"10.1016\/j.abb.2019.108073_bib147","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12986-015-0030-5","article-title":"Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1","volume":"12","author":"Kim","year":"2015","journal-title":"Nutr. Metab."},{"key":"10.1016\/j.abb.2019.108073_bib148","first-page":"201","article-title":"Obesity-induced metabolic disturbance drives oxidative stress and complement activation in the retinal environment","volume":"24","author":"Natoli","year":"2018","journal-title":"Mol. Vis."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib149","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s12886-017-0524-1","article-title":"Lutein and zeaxanthin isomers modulates lipid metabolism and the inflammatory state of retina in obesity-induced high-fat diet rodent model","volume":"17","author":"Tuzcu","year":"2017","journal-title":"BMC Ophthalmol."},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib150","doi-asserted-by":"crossref","first-page":"L707","DOI":"10.1152\/ajplung.00145.2014","article-title":"Heme oxygenase-1 attenuates acute pulmonary inflammation by decreasing the release of segmented neutrophils from the bone marrow","volume":"307","author":"Konrad","year":"2014","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib151","doi-asserted-by":"crossref","first-page":"H701","DOI":"10.1152\/ajpheart.00024.2005","article-title":"Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes","volume":"289","author":"Turkseven","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib152","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.jhep.2014.06.007","article-title":"Protective role of HO-1 and carbon monoxide in ethanol-induced hepatocyte cell death and liver injury in mice","volume":"61","author":"Bakhautdin","year":"2014","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib153","doi-asserted-by":"crossref","first-page":"H18","DOI":"10.1152\/ajpheart.00260.2010","article-title":"Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2","volume":"299","author":"Ungvari","year":"2010","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib154","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1089\/ars.2011.4360","article-title":"Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases","volume":"18","author":"Barbagallo","year":"2013","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.abb.2019.108073_bib155","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.freeradbiomed.2018.12.034","article-title":"Loss of RIP3 initiates annihilation of high-fat diet initialized nonalcoholic hepatosteatosis: a mechanism involving Toll-like receptor 4 and oxidative stress","volume":"134","author":"Chenxu","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.abb.2019.108073_bib156","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.freeradbiomed.2013.09.027","article-title":"A functional link between heme oxygenase-1 and tristetraprolin in the anti-inflammatory effects of nicotine","volume":"65","author":"Jamal","year":"2013","journal-title":"Free Radic. Biol. Med."},{"issue":"16","key":"10.1016\/j.abb.2019.108073_bib157","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1089\/ars.2012.5138","article-title":"Resveratrol induces hepatic mitochondrial biogenesis through the sequential activation of nitric oxide and carbon monoxide production","volume":"20","author":"Kim","year":"2014","journal-title":"Antioxidants Redox Signal."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib158","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.3390\/ijms14022684","article-title":"Effects of heme oxygenase-1 upregulation on blood pressure and cardiac function in an animal model of hypertensive myocardial infarction","volume":"14","author":"Chen","year":"2013","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib159","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1042\/CS20100519","article-title":"Haem oxygenase-1 counteracts the effects of interleukin-1beta on inflammatory and senescence markers in cartilage-subchondral bone explants from osteoarthritic patients","volume":"122","author":"Clerigues","year":"2012","journal-title":"Clin. Sci. (Lond.)"},{"issue":"15","key":"10.1016\/j.abb.2019.108073_bib160","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1016\/j.molimm.2010.06.013","article-title":"Heme oxygenase-1 upregulation improves lipopolysaccharide-induced acute lung injury involving suppression of macrophage migration inhibitory factor","volume":"47","author":"Yin","year":"2010","journal-title":"Mol. Immunol."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib161","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/08923970801946824","article-title":"Heme oxygenase-1 attenuates contact hypersensitivity induced by 2,4-dinitrofluorobenzene in mice, Immunopharmacol","volume":"30","author":"Pae","year":"2008","journal-title":"Immunotoxicol"},{"issue":"7","key":"10.1016\/j.abb.2019.108073_bib162","doi-asserted-by":"crossref","first-page":"R769","DOI":"10.1152\/ajpregu.00132.2014","article-title":"The heme oxygenases: important regulators of pregnancy and preeclampsia","volume":"307","author":"George","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"8","key":"10.1016\/j.abb.2019.108073_bib163","doi-asserted-by":"crossref","first-page":"R23","DOI":"10.1172\/JCI6163","article-title":"Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice","volume":"103","author":"Yet","year":"1999","journal-title":"J. Clin. Investig."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib164","doi-asserted-by":"crossref","first-page":"H368","DOI":"10.1152\/ajpheart.00093.2017","article-title":"EET intervention on Wnt1, NOV and HO-1 signaling prevents obesity-induced cardiomyopathy in obese mice","volume":"313","author":"Cao","year":"2017","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"24","key":"10.1016\/j.abb.2019.108073_bib165","doi-asserted-by":"crossref","first-page":"5765","DOI":"10.1016\/j.febslet.2006.09.032","article-title":"Endothelin-1 inhibits adipogenesis: role of phosphorylation of Akt and ERK1\/2","volume":"580","author":"Bhattacharya","year":"2006","journal-title":"FEBS Lett."},{"key":"10.1016\/j.abb.2019.108073_bib166","doi-asserted-by":"crossref","unstructured":"S. Singh, J. McClung, E. Thompson, Y. Glick, M. Greenberg, G. Acosta-Baez, B. Edris, J. Shapiro, N.G. Abraham, Cardioprotective heme oxygenase-1-PGC-1\u03b1 signaling in epicardial fat attenuates cardiovascular risk in humans as in obese mice, Obesity (article id: OBY22608; doi: 10.1002\/oby.22608 (2019)).","DOI":"10.1002\/oby.22608"},{"issue":"10","key":"10.1016\/j.abb.2019.108073_bib167","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20102514","article-title":"Positive effects of heme oxygenase upregulation on adiposity and vascular dysfunction: gene targeting vs. Pharmacologic therapy","volume":"20","author":"Peterson","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.abb.2019.108073_bib168","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/628147","article-title":"Apo A1 mimetic rescues the diabetic phenotype of HO-2 knockout mice via an increase in HO-1 adiponectin and LKBI signaling pathway","volume":"2012","author":"Cao","year":"2012","journal-title":"Int. J. Hypertens."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib169","first-page":"728","article-title":"Endothelial progenitor cell function inversely correlates with long-term glucose control in diabetic patients: association with the attenuation of the heme oxygenase-adiponectin axis","volume":"28","author":"Issan","year":"2012","journal-title":"Can. J. Cardiol."},{"issue":"23","key":"10.1016\/j.abb.2019.108073_bib170","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1161\/CIRCULATIONAHA.108.808618","article-title":"Heme oxygenase 1 determines atherosclerotic lesion progression into a vulnerable plaque","volume":"119","author":"Cheng","year":"2009","journal-title":"Circulation"},{"issue":"11","key":"10.1016\/j.abb.2019.108073_bib171","doi-asserted-by":"crossref","first-page":"H1402","DOI":"10.1152\/ajpheart.00882.2014","article-title":"Induction and functional significance of the heme oxygenase system in pathological shear stress in vivo","volume":"308","author":"Kang","year":"2015","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib172","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/sj.ki.5001565","article-title":"Heme oxygenase-1: a provenance for cytoprotective pathways in the kidney and other tissues","volume":"70","author":"Nath","year":"2006","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib173","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1681\/ASN.V115965","article-title":"Renal response to tissue injury: lessons from heme oxygenase-1 GeneAblation and expression","volume":"11","author":"Agarwal","year":"2000","journal-title":"J. Am. Soc. Nephrol."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib174","doi-asserted-by":"crossref","first-page":"273","DOI":"10.18388\/abp.2005_3440","article-title":"Heme oxygenase-1 expression in disease states","volume":"52","author":"Deshane","year":"2005","journal-title":"Acta Biochim. Pol."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib175","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1161\/01.HYP.38.2.210","article-title":"Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats","volume":"38","author":"Sabaawy","year":"2001","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib176","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1681\/ASN.2004121082","article-title":"Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction","volume":"17","author":"Goodman","year":"2006","journal-title":"J. Am. Soc. Nephrol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib177","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1161\/01.HYP.0000250086.06137.fb","article-title":"Role of renal medullary heme oxygenase in the regulation of pressure natriuresis and arterial blood pressure","volume":"49","author":"Li","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.abb.2019.108073_bib178","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1161\/01.HYP.0000085785.40581.1A","article-title":"Effects of exogenous heme on renal function. Role of heme oxygenase and cyclooxygenase","volume":"42","author":"Rodriguez","year":"2003","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib179","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1161\/01.HYP.0000111721.97169.97","article-title":"Nitric oxide synthesis inhibition promotes renal production of carbon monoxide","volume":"43","author":"Rodriguez","year":"2004","journal-title":"Hypertension"},{"issue":"3 Pt 2","key":"10.1016\/j.abb.2019.108073_bib180","first-page":"H1132","article-title":"Heme oxygenase substrates acutely lower blood pressure in hypertensive rats","volume":"271","author":"Johnson","year":"1996","journal-title":"Am. J. Physiol."},{"issue":"10","key":"10.1016\/j.abb.2019.108073_bib181","doi-asserted-by":"crossref","first-page":"H1471","DOI":"10.1152\/ajpheart.00962.2012","article-title":"Upregulation of heme oxygenase-1 potentiates EDH-type relaxations in the mesenteric artery of the spontaneously hypertensive rat","volume":"305","author":"Li","year":"2013","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib182","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1681\/ASN.2011050455","article-title":"Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension","volume":"23","author":"Stec","year":"2012","journal-title":"J. Am. Soc. Nephrol."},{"issue":"39","key":"10.1016\/j.abb.2019.108073_bib183","doi-asserted-by":"crossref","first-page":"36059","DOI":"10.1074\/jbc.R100030200","article-title":"Epoxygenase pathways of arachidonic acid metabolism","volume":"276","author":"Zeldin","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib184","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0022-2275(20)32049-6","article-title":"Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase","volume":"41","author":"Capdevila","year":"2000","journal-title":"J. Lipid Res."},{"issue":"5431","key":"10.1016\/j.abb.2019.108073_bib185","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1126\/science.285.5431.1276","article-title":"Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids","volume":"285","author":"Node","year":"1999","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib186","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.abb.2004.10.009","article-title":"Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids","volume":"433","author":"Spiecker","year":"2005","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.abb.2019.108073_bib187","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9039754","article-title":"Downregulation of PGC-1alpha prevents the beneficial effect of EET-heme oxygenase-1 on mitochondrial integrity and associated metabolic function in obese mice","volume":"2016","author":"Singh","year":"2016","journal-title":"J. Nutr. Metab"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib188","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.hlc.2004.02.008","article-title":"Role of oxidative stress in cardiac remodelling after myocardial infarction","volume":"13","author":"Grieve","year":"2004","journal-title":"Heart Lung Circ."},{"issue":"13","key":"10.1016\/j.abb.2019.108073_bib189","doi-asserted-by":"crossref","first-page":"5987","DOI":"10.1073\/pnas.91.13.5987","article-title":"Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene","volume":"91","author":"Lavrovsky","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"7561","key":"10.1016\/j.abb.2019.108073_bib190","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1038\/nature14569","article-title":"Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment","volume":"523","author":"Li","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.abb.2019.108073_bib191","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.prostaglandins.2016.07.004","article-title":"PGC-1 alpha regulates HO-1 expression, mitochondrial dynamics and biogenesis: role of epoxyeicosatrienoic acid","volume":"125","author":"Singh","year":"2016","journal-title":"Prostaglandins Other Lipid Mediat."},{"issue":"14","key":"10.1016\/j.abb.2019.108073_bib192","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1089\/scd.2016.0072","article-title":"Epoxyeicosatrienoic acids regulate adipocyte differentiation of mouse 3T3 cells, via PGC-1alpha activation, which is required for HO-1 expression and increased mitochondrial function","volume":"25","author":"Waldman","year":"2016","journal-title":"Stem Cells Dev."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib193","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1002\/jcb.22486","article-title":"Improved myocardial perfusion in chronic diabetic mice by the up-regulation of pLKB1 and AMPK signaling","volume":"109","author":"Kusmic","year":"2010","journal-title":"J. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib194","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2005.03.010","article-title":"Heme oxygenase and the cardiovascular-renal system","volume":"39","author":"Abraham","year":"2005","journal-title":"Free Radic. Biol. Med."},{"issue":"7","key":"10.1016\/j.abb.2019.108073_bib195","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1172\/JCI5342","article-title":"Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury","volume":"103","author":"Otterbein","year":"1999","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.abb.2019.108073_bib196","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.prostaglandins.2018.07.004","article-title":"Ablation of soluble epoxide hydrolase reprogram white fat to beige-like fat through an increase in mitochondrial integrity, HO-1-adiponectin in vitro and in vivo","volume":"138","author":"Liu","year":"2018","journal-title":"Prostaglandins Other Lipid Mediat."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib197","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/ijo.2011.78","article-title":"Chronic HO-1 induction with cobalt protoporphyrin (CoPP) treatment increases oxygen consumption, activity, heat production and lowers body weight in obese melanocortin-4 receptor-deficient mice","volume":"36","author":"Csongradi","year":"2012","journal-title":"Int. J. Obes."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib198","doi-asserted-by":"crossref","first-page":"R207","DOI":"10.1152\/ajpregu.00517.2011","article-title":"Heme oxygenase, a novel target for the treatment of hypertension and obesity?","volume":"302","author":"Hosick","year":"2012","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib199","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0087936","article-title":"The heme oxygenase system suppresses perirenal visceral adiposity, abates renal inflammation and ameliorates diabetic nephropathy in Zucker diabetic fatty rats","volume":"9","author":"Ndisang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.abb.2019.108073_bib200","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.prostaglandins.2018.05.008","article-title":"EET enhances renal function in obese mice resulting in restoration of HO-1-Mfn1\/2 signaling, and decrease in hypertension through inhibition of sodium chloride co-transporter","volume":"137","author":"Schragenheim","year":"2018","journal-title":"Prostaglandins Other Lipid Mediat."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib201","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/ijo.2013.61","article-title":"Chronic carbon monoxide treatment attenuates development of obesity and remodels adipocytes in mice fed a high-fat diet","volume":"38","author":"Hosick","year":"2014","journal-title":"Int. J. Obes."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib202","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.tips.2015.09.003","article-title":"Translational significance of heme oxygenase in obesity and metabolic syndrome","volume":"37","author":"Abraham","year":"2016","journal-title":"Trends Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib203","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0055369","article-title":"Adipose overexpression of heme oxygenase-1 does not protect against high fat diet-induced insulin resistance in mice","volume":"8","author":"Huang","year":"2013","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib204","doi-asserted-by":"crossref","first-page":"E244","DOI":"10.1152\/ajpendo.00396.2016","article-title":"Mice with hyperbilirubinemia due to Gilbert's syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPARalpha","volume":"312","author":"Hinds","year":"2017","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib205","doi-asserted-by":"crossref","first-page":"68","DOI":"10.7899\/1042-5055-29.1.68","article-title":"Call for scientific submissions 2016 ACC RAC","volume":"29","year":"2015","journal-title":"J. Chiropr. Educ."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib206","doi-asserted-by":"crossref","first-page":"G668","DOI":"10.1152\/ajpgi.00026.2018","article-title":"Biliverdin reductase and bilirubin in hepatic disease","volume":"314","author":"Weaver","year":"2018","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib207","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.neuron.2017.09.056","article-title":"Cell biology of astrocyte-synapse interactions","volume":"96","author":"Allen","year":"2017","journal-title":"Neuron"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib208","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.tem.2015.02.001","article-title":"Biliverdin reductase isozymes in metabolism","volume":"26","author":"O'Brien","year":"2015","journal-title":"Trends Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib209","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/21623945.2015.1038443","article-title":"Chronic treatment with a carbon monoxide releasing molecular revereses dietary induced obesity in mice","volume":"5","author":"Hosick","year":"2016","journal-title":"Adipocyte"},{"issue":"22","key":"10.1016\/j.abb.2019.108073_bib210","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.123485","article-title":"Carbon monoxide-induced metabolic switch in adipocytes improves insulin resistance in obese mice","volume":"3","author":"Braud","year":"2018","journal-title":"JCI Insight"},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib211","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1002\/oby.20559","article-title":"Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21","volume":"22","author":"Hinds","year":"2014","journal-title":"Obesity"},{"issue":"1\u20132","key":"10.1016\/j.abb.2019.108073_bib212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.prostaglandins.2011.10.002","article-title":"Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications","volume":"97","author":"Burgess","year":"2012","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1016\/j.abb.2019.108073_bib213","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/6598326","article-title":"Oxidative stress in cardiac tissue of patients undergoing coronary artery bypass graft surgery: the effects of overweight and obesity","volume":"2018","author":"Gramlich","year":"2018","journal-title":"Oxid. Med. Cell Longev."},{"issue":"11","key":"10.1016\/j.abb.2019.108073_bib214","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jnutbio.2018.01.017","article-title":"Raspberry ketone induces brown-like adipocyte formation through suppression of autophagy in adipocytes and adipose tissue","volume":"56","author":"Leu","year":"2018","journal-title":"J. Nutr. Biochem."},{"issue":"11","key":"10.1016\/j.abb.2019.108073_bib215","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18112268","article-title":"The inhibitory effects of cobalt protoporphyrin IX and cannabinoid 2 receptor agonists in type 2 diabetic mice","volume":"18","author":"McDonnell","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"13","key":"10.1016\/j.abb.2019.108073_bib216","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.2174\/0929867324666170616110748","article-title":"Effects of polyphenolic derivatives on heme oxygenase-system in metabolic dysfunctions","volume":"25","author":"Pittala","year":"2018","journal-title":"Curr. Med. Chem."},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib217","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1161\/01.RES.0000249616.10603.d6","article-title":"CD163-Mediated hemoglobin-heme uptake activates macrophage HO-1, providing an antiinflammatory function","volume":"99","author":"Abraham","year":"2006","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib218","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1161\/01.RES.0000109414.78907.F9","article-title":"Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery","volume":"94","author":"Philippidis","year":"2004","journal-title":"Circ. Res."},{"issue":"11","key":"10.1016\/j.abb.2019.108073_bib219","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1038\/ijo.2009.160","article-title":"Diminished upregulation of visceral adipose heme oxygenase-1 correlates with waist-to-hip ratio and insulin resistance","volume":"33","author":"Shakeri-Manesch","year":"2009","journal-title":"Int. J. Obes."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib220","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/MBC.0000000000000194","article-title":"Bariatric patients have plasmatic hypercoagulability and systemic upregulation of heme oxygenase activity","volume":"26","author":"Nielsen","year":"2015","journal-title":"Blood Coagul. Fibrinolysis"},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib221","first-page":"2","article-title":"Sources of carbon monoxide (CO) in biological systems and applications of CO detection technologies","volume":"18","author":"Rodgers","year":"1994","journal-title":"Semin. Perinatol."},{"issue":"6","key":"10.1016\/j.abb.2019.108073_bib222","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1089\/1523086042259823","article-title":"Heme degradation by reactive oxygen species","volume":"6","author":"Nagababu","year":"2004","journal-title":"Antioxidants Redox Signal."},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib223","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1124\/pr.57.4.3","article-title":"Carbon monoxide: endogenous production, physiological functions, and pharmacological applications","volume":"57","author":"Wu","year":"2005","journal-title":"Pharmacol. Rev."},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib224","doi-asserted-by":"crossref","first-page":"H1744","DOI":"10.1152\/ajpheart.01088.2004","article-title":"Hyperglycemia alters PI3k and akt signaling and leads to endothelial cell proliferative dysfunction","volume":"289","author":"Varma","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"12","key":"10.1016\/j.abb.2019.108073_bib225","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1007\/s00125-004-1572-7","article-title":"Antioxidative treatment prevents activation of death-receptor- and mitochondrion-dependent apoptosis in the hearts of diabetic rats","volume":"47","author":"Bojunga","year":"2004","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib226","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1210\/en.2003-1274","article-title":"Insulin-like growth factor (IGF)-I\/IGF-binding protein-3 complex: therapeutic efficacy and mechanism of protection against type 1 diabetes","volume":"145","author":"Chen","year":"2004","journal-title":"Endocrinology"},{"issue":"11","key":"10.1016\/j.abb.2019.108073_bib227","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.2337\/diabetes.49.11.1932","article-title":"Diabetic peripheral neuropathy: evidence for apoptosis and associated mitochondrial dysfunction","volume":"49","author":"Srinivasan","year":"2000","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib228","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.mcn.2004.08.009","article-title":"Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons","volume":"28","author":"Huang","year":"2005","journal-title":"Mol. Cell. Neurosci."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib229","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1093\/nar\/21.5.1103","article-title":"Ultraviolet A (320-380 nm) radiation causes an alteration in the binding of a specific protein\/protein complex to a short region of the promoter of the human heme oxygenase 1 gene","volume":"21","author":"Nascimento","year":"1993","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib230","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1172\/JCI448","article-title":"Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2","volume":"101","author":"Dennery","year":"1998","journal-title":"J. Clin. Investig."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib231","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jphs.2018.09.010","article-title":"Improved endogenous epoxyeicosatrienoic acid production mends heart function via increased PGC 1alpha-mitochondrial functions in metabolic syndrome","volume":"138","author":"Liu","year":"2018","journal-title":"J. Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib232","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1159\/000477864","article-title":"Irisin regulates heme oxygenase-1\/adiponectin Axis in perivascular adipose tissue and improves endothelial dysfunction in diet-induced obese mice","volume":"42","author":"Hou","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"issue":"7","key":"10.1016\/j.abb.2019.108073_bib233","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.amjcard.2009.11.034","article-title":"Usefulness of clopidogrel to protect against diabetes-induced vascular damage","volume":"105","author":"McClung","year":"2010","journal-title":"Am. J. Cardiol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib234","article-title":"Ablation of adipose-HO-1 expression increases white fat over beige fat through inhibition of mitochondrial fusion and of PGC1alpha in female mice","volume":"31","author":"Singh","year":"2017","journal-title":"Horm. Mol. Biol. Clin. Investig."},{"key":"10.1016\/j.abb.2019.108073_bib235","first-page":"2329","article-title":"CYP-450 epoxygenase derived epoxyeicosatrienoic acid contribute to reversal of heart failure in obesity-induced diabetic cardiomyopathy via PGC-1 alpha activation","author":"Singh","year":"2018","journal-title":"Cardiovasc. Pharmacol. (Open Access)"},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib236","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/BF02342435","article-title":"Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation","volume":"35","author":"Rabinovitch","year":"1992","journal-title":"Diabetologia"},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib237","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.bbrc.2004.12.106","article-title":"Critical role of heme oxygenase-1 in Foxp3-mediated immune suppression","volume":"327","author":"Choi","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"8","key":"10.1016\/j.abb.2019.108073_bib238","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.4049\/jimmunol.172.8.4744","article-title":"Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production","volume":"172","author":"Pae","year":"2004","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib239","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1182\/blood-2005-02-0494","article-title":"Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression","volume":"106","author":"Chauveau","year":"2005","journal-title":"Blood"},{"issue":"10","key":"10.1016\/j.abb.2019.108073_bib240","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078209","article-title":"Administration of heme arginate ameliorates murine type 2 diabetes independently of heme oxygenase activity","volume":"8","author":"Choudhary","year":"2013","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib241","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.2337\/diabetes.50.9.1983","article-title":"Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation","volume":"50","author":"Pileggi","year":"2001","journal-title":"Diabetes"},{"issue":"11","key":"10.1016\/j.abb.2019.108073_bib242","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1111\/j.1742-4658.2006.05224.x","article-title":"Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase\/Akt pathway and the Nrf2 transcription factor in renal cells","volume":"273","author":"Harrison","year":"2006","journal-title":"FEBS J."},{"issue":"3","key":"10.1016\/j.abb.2019.108073_bib243","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1006\/bbrc.1996.0135","article-title":"Downregulation of the human heme oxygenase gene by glucocorticoids and identification of 56b regulatory elements","volume":"218","author":"Lavrovsky","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib244","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1086\/302729","article-title":"Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema","volume":"66","author":"Yamada","year":"2000","journal-title":"Am. J. Hum. Genet."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib245","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1177\/152660280100800501","article-title":"Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with restenosis after percutaneous transluminal angioplasty","volume":"8","author":"Exner","year":"2001","journal-title":"J. Endovasc. Ther."},{"issue":"12","key":"10.1016\/j.abb.2019.108073_bib246","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1001\/jama.298.12.1398-b","article-title":"Relationship between Gilbert syndrome and prevalence of vascular complications in patients with diabetes","volume":"298","author":"Inoguchi","year":"2007","journal-title":"J. Am. Med. Assoc."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib247","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00439-002-0769-4","article-title":"Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients","volume":"111","author":"Chen","year":"2002","journal-title":"Hum. Genet."},{"issue":"10","key":"10.1016\/j.abb.2019.108073_bib248","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1161\/01.ATV.0000033515.96747.6F","article-title":"Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors, Arterioscler","volume":"22","author":"Kaneda","year":"2002","journal-title":"Thromb. Vasc. Biol"},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib249","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1160\/TH03-05-0291","article-title":"A microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with increased bilirubin and HDL levels but not with coronary artery disease, Thromb","volume":"91","author":"Endler","year":"2004","journal-title":"Haemost"},{"issue":"8","key":"10.1016\/j.abb.2019.108073_bib250","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1093\/eurheartj\/ehm036","article-title":"Heme oxygenase-1 gene promoter polymorphism and restenosis following coronary stenting","volume":"28","author":"Tiroch","year":"2007","journal-title":"Eur. Heart J."},{"issue":"4","key":"10.1016\/j.abb.2019.108073_bib251","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1111\/j.1600-6143.2006.01726.x","article-title":"Association of functional heme oxygenase-1 gene promoter polymorphism with renal transplantation outcomes","volume":"7","author":"Courtney","year":"2007","journal-title":"Am. J. Transplant."},{"issue":"2","key":"10.1016\/j.abb.2019.108073_bib252","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.atherosclerosis.2003.11.021","article-title":"A promoter variant of the heme oxygenase-1 gene may reduce the incidence of ischemic heart disease in Japanese","volume":"173","author":"Ono","year":"2004","journal-title":"Atherosclerosis"},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib253","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/01.fpc.0000205001.07054.fa","article-title":"Restenosis after percutaneous coronary intervention is associated with the angiotensin-II type-1 receptor 1166A\/C polymorphism but not with polymorphisms of angiotensin-converting enzyme, angiotensin-II receptor, angiotensinogen or heme oxygenase-1","volume":"16","author":"Wijpkema","year":"2006","journal-title":"Pharmacogenetics Genom."},{"issue":"7","key":"10.1016\/j.abb.2019.108073_bib254","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0199994","article-title":"Microsatellite polymorphism in the Heme oxygenase-1 gene promoter is associated with dermal collagen density in Japanese obese male subjects","volume":"13","author":"Ibuki","year":"2018","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib255","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1161\/ATVBAHA.114.304729","article-title":"Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease","volume":"35","author":"Pechlaner","year":"2015","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"1","key":"10.1016\/j.abb.2019.108073_bib256","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1186\/s12885-018-5141-8","article-title":"Activation of antioxidant defences of human mammary epithelial cells under leptin depend on neoplastic state","volume":"18","author":"Mahbouli","year":"2018","journal-title":"BMC Canc."},{"issue":"5","key":"10.1016\/j.abb.2019.108073_bib257","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1080\/01443615.2017.1286463","article-title":"Markers of obesity and growth in preeclamptic and normotensive pregnant women","volume":"37","author":"Kharb","year":"2017","journal-title":"J. Obstet. Gynaecol."},{"issue":"10","key":"10.1016\/j.abb.2019.108073_bib258","doi-asserted-by":"crossref","first-page":"1","DOI":"10.14715\/cmb\/2018.64.10.1","article-title":"Role of statin as inducer of Hmox-1 system in treatment of preeclampsia","volume":"64","author":"Putra","year":"2018","journal-title":"Cell. Mol. Biol. (Noisy-Le-Grand)"},{"issue":"9","key":"10.1016\/j.abb.2019.108073_bib259","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1007\/s11695-017-2635-4","article-title":"Impact of bariatric surgery on heme oxygenase-1, inflammation, and insulin resistance in morbid obesity with obstructive sleep apnea","volume":"27","author":"Tirado","year":"2017","journal-title":"Obes. Surg."}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986119304175?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986119304175?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T06:10:23Z","timestamp":1757743823000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986119304175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":259,"alternative-id":["S0003986119304175"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2019.108073","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HO-1 overexpression and underexpression: Clinical implications","name":"articletitle","label":"Article Title"},{"value":"Archives of Biochemistry and Biophysics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abb.2019.108073","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"108073"}}