{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T07:14:02Z","timestamp":1788246842286,"version":"build-2803163510"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100006162","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Ci\u00eancia e Tecnologia do Estado de Pernambuco","doi-asserted-by":"publisher","award":["APQ-1072-2.07\/15"],"award-info":[{"award-number":["APQ-1072-2.07\/15"]}],"id":[{"id":"10.13039\/501100006162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006162","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Ci\u00eancia e Tecnologia do Estado de Pernambuco","doi-asserted-by":"publisher","award":["IBPG-0639-2.07\/14"],"award-info":[{"award-number":["IBPG-0639-2.07\/14"]}],"id":[{"id":"10.13039\/501100006162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006162","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Ci\u00eancia e Tecnologia do Estado de Pernambuco","doi-asserted-by":"publisher","award":["APQ-1133-2.07\/2012"],"award-info":[{"award-number":["APQ-1133-2.07\/2012"]}],"id":[{"id":"10.13039\/501100006162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000735","name":"University of Cambridge","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["474004\/2013-9"],"award-info":[{"award-number":["474004\/2013-9"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["307366\/2015-4"],"award-info":[{"award-number":["307366\/2015-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["432468\/2016-1"],"award-info":[{"award-number":["432468\/2016-1"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007880","name":"Johns Hopkins University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007880","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.abb.2020.108306","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T11:24:05Z","timestamp":1581938645000},"page":"108306","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Maternal endotoxemia induces renal collagen deposition in adult offspring: Role of NADPH oxidase\/TGF-\u03b21\/MMP-2 signaling pathway"],"prefix":"10.1016","volume":"684","author":[{"given":"Juliane S.","family":"Farias","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly M.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lia K.S.","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edjair V.","family":"Cabral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina S.","family":"Aires","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alana C.","family":"Veras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana D.","family":"Paix\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leucio D.","family":"Vieira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.abb.2020.108306_bib1","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1095\/biolreprod.113.111823","article-title":"How the kidney is impacted by the perinatal maternal environment to develop hypertension","volume":"89","author":"Paix\u00e3o","year":"2013","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.abb.2020.108306_bib2","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1152\/physrev.00029.2013","article-title":"Early developmental conditioning of later health and disease: physiology or pathophysiology?","volume":"94","author":"Hanson","year":"2014","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.abb.2020.108306_bib3","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1745-7254.2007.00593.x","article-title":"Prenatal exposure to lipopolysaccharide results in increases in blood pressure and body weight in rats","volume":"28","author":"Wei","year":"2007","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.abb.2020.108306_bib4","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1111\/j.1440-1681.2008.05062.x","article-title":"Prenatal exposure to zymosan results in hypertension in adult offspring rats","volume":"35","author":"Liao","year":"2008","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.abb.2020.108306_bib5","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.lfs.2011.07.017","article-title":"Maternal inflammation, growth retardation, and preterm birth: insights into adult cardiovascular disease","volume":"89","author":"Rogers","year":"2011","journal-title":"Life Sci."},{"key":"10.1016\/j.abb.2020.108306_bib6","doi-asserted-by":"crossref","first-page":"3577","DOI":"10.1016\/j.bbadis.2018.09.019","article-title":"Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II\/NADPH oxidase pathway: prevention by early treatment with \u03b1-tocopherol","volume":"1864","author":"Vieira","year":"2018","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."},{"key":"10.1016\/j.abb.2020.108306_bib7","article-title":"Post-natal inhibition of NF-\u03baB activation prevents renal damage caused by prenatal LPS exposure","volume":"11","author":"Guo","year":"2016","journal-title":"PloS One"},{"key":"10.1016\/j.abb.2020.108306_bib8","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1755-1536-7-4","article-title":"The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?","volume":"7","author":"Genovese","year":"2014","journal-title":"Fibrogenesis Tissue Repair"},{"key":"10.1016\/j.abb.2020.108306_bib9","doi-asserted-by":"crossref","DOI":"10.1093\/ndt\/gfw330","article-title":"The ascending rank of chronic kidney disease in the global burden of disease study","volume":"32","author":"Jager","year":"2017","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.abb.2020.108306_bib10","doi-asserted-by":"crossref","first-page":"F167","DOI":"10.1152\/ajprenal.00503.2014","article-title":"The discovery of hypertension: evolving views on the role of the kidneys, and current hot topics","volume":"308","author":"Johnson","year":"2015","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.abb.2020.108306_bib11","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3389\/fphys.2018.00105","article-title":"Oxidative stress and renal fibrosis: recent insights for the development of novel therapeutic strategies","volume":"9","author":"Lv","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.abb.2020.108306_bib12","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1681\/ASN.2009020146","article-title":"NAD(P)H oxidase mediates TGF-\u03b21-induced activation of kidney myofibroblasts","volume":"21","author":"Bondi","year":"2010","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.abb.2020.108306_bib13","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.cellsig.2012.10.003","article-title":"TGF-\u03b2 signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities","volume":"25","author":"Samarakoon","year":"2013","journal-title":"Cell. Signal."},{"key":"10.1016\/j.abb.2020.108306_bib14","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.trsl.2014.07.010","article-title":"Therapeutic targets for treating fibrotic kidney diseases","volume":"165","author":"Lee","year":"2015","journal-title":"Transl. Res."},{"key":"10.1016\/j.abb.2020.108306_bib15","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1152\/physrev.00015.2015","article-title":"In utero origins of hypertension: mechanisms and targets for therapy","volume":"96","author":"Morton","year":"2016","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.abb.2020.108306_bib16","doi-asserted-by":"crossref","DOI":"10.3390\/biom9040141","article-title":"Unilateral ureteral obstruction as a model to investigate fibrosis-attenuating treatments","volume":"9","author":"Mart\u00ednez-Klimova","year":"2019","journal-title":"Biomolecules"},{"key":"10.1016\/j.abb.2020.108306_bib17","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0895-7061(97)00360-9","article-title":"Gender differences in the renal nitric oxide (NO) system: dissociation between expression of endothelial NO synthase and renal hemodynamic response to NO synthase inhibition","volume":"11","author":"Reckelhoff","year":"1998","journal-title":"Am. J. Hypertens."},{"key":"10.1016\/j.abb.2020.108306_bib18","first-page":"R970","article-title":"Hemodynamic effect of 17\u03b2-estradiol in absence of NO in ovariectomized rats: role of angiotensin II","volume":"274","author":"Hern\u00e1ndez","year":"1998","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.abb.2020.108306_bib19","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.abb.2020.108306_bib20","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1007\/s00467-011-1908-8","article-title":"Alpha-tocopherol prevents intrauterine undernutrition-induced oligonephronia in rats","volume":"26","author":"Vieira-Filho","year":"2011","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.abb.2020.108306_bib21","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1007\/s00467-009-1166-1","article-title":"Effect of all-trans retinoic acid on renal expressions of matrix metalloproteinase-2, matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in rats with glomerulosclerosis","volume":"24","author":"Qin","year":"2009","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.abb.2020.108306_bib22","doi-asserted-by":"crossref","first-page":"F1351","DOI":"10.1152\/ajprenal.00037.2012","article-title":"Matrix metalloproteinases in kidney homeostasis and diseases","volume":"302","author":"Tan","year":"2012","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.abb.2020.108306_bib23","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/biolre\/iox072","article-title":"Persistence of risk factors associated with maternal cardiovascular disease following aberrant inflammation in rat pregnancy","volume":"97","author":"Ushida","year":"2017","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.abb.2020.108306_bib24","doi-asserted-by":"crossref","first-page":"14807","DOI":"10.1038\/s41598-017-14926-4","article-title":"Experimental preeclampsia in rats affects vascular gene expression patterns","volume":"7","author":"Lip","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.abb.2020.108306_bib25","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1111\/jog.14085","article-title":"A rat model of placental inflammation explains the unexplained elevated maternal serum alpha-fetoprotein associated with adverse pregnancy outcomes","volume":"45","author":"Hu","year":"2019","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"10.1016\/j.abb.2020.108306_bib26","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s11906-016-0637-6","article-title":"Preterm birth and hypertension: is there a link?","volume":"18","author":"Bertagnolli","year":"2016","journal-title":"Curr. Hypertens. Rep."},{"key":"10.1016\/j.abb.2020.108306_bib27","doi-asserted-by":"crossref","first-page":"S869","DOI":"10.1016\/j.ajog.2017.12.012","article-title":"Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease","volume":"218","author":"Crispi","year":"2018","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.abb.2020.108306_bib28","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1097\/HJH.0000000000000612","article-title":"Effect of birth weight on life-course blood pressure levels among children born premature: the cardiovascular risk in young Finns study","volume":"33","author":"Juonala","year":"2015","journal-title":"J. Hypertens."},{"key":"10.1016\/j.abb.2020.108306_bib29","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1113\/jphysiol.1977.sp012061","article-title":"Developmental changes in nephron number, proximal tubular length and superficial nephron glomerular filtration rate of rats","volume":"272","author":"Solomon","year":"1977","journal-title":"J. Physiol."},{"key":"10.1016\/j.abb.2020.108306_bib30","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0163-7827(99)00008-9","article-title":"Vitamin E and its function in membranes","volume":"38","author":"Wang","year":"1999","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.abb.2020.108306_bib31","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1017\/S0007114513004236","article-title":"Renal molecular mechanisms underlying altered Na+ handling and genesis of hypertension during adulthood in prenatally undernourished rats","volume":"111","author":"Vieira-Filho","year":"2014","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.abb.2020.108306_bib32","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1523-1755.2005.67097.x","article-title":"Pathways to nephron loss starting from glomerular diseases-insights from animal models","volume":"67","author":"Kriz","year":"2005","journal-title":"Kidney Int."},{"key":"10.1016\/j.abb.2020.108306_bib33","doi-asserted-by":"crossref","first-page":"F155","DOI":"10.1152\/ajprenal.00272.2002","article-title":"Altered expression of major renal Na transporters in rats with unilateral ureteral obstruction","volume":"284","author":"Li","year":"2003","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.abb.2020.108306_bib34","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1089\/ars.2016.6665","article-title":"Oxidant mechanisms in renal injury and disease","volume":"25","author":"Ratliff","year":"2016","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.abb.2020.108306_bib35","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12882-017-0490-0","article-title":"Biomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review","volume":"18","author":"Mansour","year":"2017","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.abb.2020.108306_bib36","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s00441-011-1169-7","article-title":"Mechanisms and consequences of TGF-\u03b2 overexpression by podocytes in progressive podocyte disease","volume":"347","author":"Lee","year":"2012","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.abb.2020.108306_bib37","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.transproceed.2011.12.054","article-title":"Role of reactive oxygen species in transforming growth factor-beta1-induced extracellular matrix accumulation in renal tubular epithelial cells","volume":"44","author":"Rhyu","year":"2012","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.abb.2020.108306_bib38","first-page":"1077","article-title":"Redox-mediated activation of latent transforming growth factor-\u03b21","volume":"10","author":"Barcellos-Hoff","year":"1996","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.abb.2020.108306_bib39","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.redox.2014.01.012","article-title":"NADPH oxidase-dependent redox signaling in TGF-\u03b2-mediated fibrotic responses","volume":"2","author":"Jiang","year":"2014","journal-title":"Redox Biol."},{"key":"10.1016\/j.abb.2020.108306_bib40","doi-asserted-by":"crossref","first-page":"160","DOI":"10.2307\/3580089","article-title":"Irradiation of rat mesangial cells alters the expression of gene products associated with the development of renal fibrosis","volume":"152","author":"Zhao","year":"1999","journal-title":"Radiat. Res."},{"key":"10.1016\/j.abb.2020.108306_bib41","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1038\/labinvest.2012.68","article-title":"Involvement of matrix metalloproteinase-2 in the development of renal interstitial fibrosis in mouse obstructive nephropathy","volume":"92","author":"Du","year":"2012","journal-title":"Lab. Invest."},{"key":"10.1016\/j.abb.2020.108306_bib42","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1146\/annurev.cellbio.17.1.463","article-title":"How matrix metalloproteinases regulate cell behavior","volume":"17","author":"Sternlicht","year":"2001","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.abb.2020.108306_bib43","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00467-016-3383-8","article-title":"Life expectancy with chronic kidney disease: an educational review","volume":"32","author":"Neild","year":"2017","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.abb.2020.108306_bib44","doi-asserted-by":"crossref","first-page":"2458","DOI":"10.1016\/j.bbadis.2018.04.007","article-title":"Perinatal \u03b1-tocopherol overload programs alterations in kidney development and renal angiotensin II signaling pathways at birth and at juvenile age: mechanisms underlying the development of elevated blood pressure","volume":"1864","author":"Ribeiro","year":"2018","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986119308744?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986119308744?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T04:42:56Z","timestamp":1778647376000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986119308744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":44,"alternative-id":["S0003986119308744"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2020.108306","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal endotoxemia induces renal collagen deposition in adult offspring: Role of NADPH oxidase\/TGF-\u03b21\/MMP-2 signaling pathway","name":"articletitle","label":"Article Title"},{"value":"Archives of Biochemistry and Biophysics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abb.2020.108306","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108306"}}