{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:59:58Z","timestamp":1792789198295,"version":"4.5.0"},"reference-count":195,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81702802"],"award-info":[{"award-number":["81702802"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002888","name":"Beijing Municipal Commission of Education","doi-asserted-by":"publisher","award":["KM201910005005"],"award-info":[{"award-number":["KM201910005005"]}],"id":[{"id":"10.13039\/501100002888","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.abb.2021.109083","type":"journal-article","created":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T17:30:33Z","timestamp":1636824633000},"page":"109083","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["tRNA modifications and their potential roles in pancreatic cancer"],"prefix":"10.1016","volume":"714","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9881-4197","authenticated-orcid":false,"given":"Hua","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1587-5681","authenticated-orcid":false,"given":"Huan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2974-0822","authenticated-orcid":false,"given":"Ruining","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0896-2082","authenticated-orcid":false,"given":"Xinhui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib1","first-page":"7","article-title":"Cancer statistics, 2021","volume":"71","author":"Siegel","year":"2021","journal-title":"Ca - Cancer J. Clin."},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib2","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1158\/0008-5472.CAN-14-0155","article-title":"Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States","volume":"74","author":"Rahib","year":"2014","journal-title":"Cancer Res."},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/cancers12113096","article-title":"Pancreatic cancer (PDAC): introduction of evidence-based complementary measures into integrative clinical management","volume":"12","author":"Jentzsch","year":"2020","journal-title":"Cancers (Basel)"},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib4","doi-asserted-by":"crossref","first-page":"59","DOI":"10.21037\/cco.2017.12.01","article-title":"Pathologic classification of \"pancreatic cancers\": current concepts and challenges","volume":"6","author":"Mostafa","year":"2017","journal-title":"Chin. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib5","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s10555-020-09952-0","article-title":"An overview of genetic mutations and epigenetic signatures in the course of pancreatic cancer progression","volume":"40","author":"Khan","year":"2021","journal-title":"Cancer Metastasis Rev."},{"issue":"12","key":"10.1016\/j.abb.2021.109083_bib6","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1080\/15592294.2019.1640546","article-title":"Epidrugs: targeting epigenetic marks in cancer treatment","volume":"14","author":"Miranda Furtado","year":"2019","journal-title":"Epigenetics"},{"key":"10.1016\/j.abb.2021.109083_bib7","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/B978-0-12-380866-0.60002-2","article-title":"DNA methylation and cancer","volume":"70","author":"Kulis","year":"2010","journal-title":"Adv. Genet."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib8","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1002\/cncr.25482","article-title":"The role of epigenetic transcription repression and DNA methyltransferases in cancer","volume":"117","author":"Daniel","year":"2011","journal-title":"Cancer"},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib9","first-page":"1115","article-title":"miR-216a-mediated upregulation of TSPAN1 contributes to pancreatic cancer progression via transcriptional regulation of ITGA2","volume":"10","author":"Wang","year":"2020","journal-title":"Am J Cancer Res"},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib10","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1093\/carcin\/bgi361","article-title":"DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas","volume":"27","author":"Peng","year":"2006","journal-title":"Carcinogenesis"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib11","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1186\/s12943-019-1109-9","article-title":"Functions of N6-methyladenosine and its role in cancer","volume":"18","author":"He","year":"2019","journal-title":"Mol. Cancer"},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib12","doi-asserted-by":"crossref","first-page":"152666","DOI":"10.1016\/j.prp.2019.152666","article-title":"The RNA m6A methyltransferase METTL3 promotes pancreatic cancer cell proliferation and invasion","volume":"215","author":"Xia","year":"2019","journal-title":"Pathol. Res. Pract."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12943-019-1128-6","article-title":"m(6)A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling","volume":"19","author":"Tang","year":"2020","journal-title":"Mol. Cancer"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib14","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s12943-020-01158-w","article-title":"RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner","volume":"19","author":"Guo","year":"2020","journal-title":"Mol. Cancer"},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib15","doi-asserted-by":"crossref","first-page":"e3000664","DOI":"10.1371\/journal.pbio.3000664","article-title":"YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators","volume":"18","author":"Fei","year":"2020","journal-title":"PLoS Biol."},{"issue":"23","key":"10.1016\/j.abb.2021.109083_bib16","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1080\/15384101.2017.1380125","article-title":"YTH domain family 2 orchestrates epithelial-mesenchymal transition\/proliferation dichotomy in pancreatic cancer cells","volume":"16","author":"Chen","year":"2017","journal-title":"Cell Cycle"},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib17","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.molmed.2014.01.008","article-title":"Role of tRNA modifications in human diseases","volume":"20","author":"Torres","year":"2014","journal-title":"Trends Mol. Med."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib18","doi-asserted-by":"crossref","DOI":"10.3390\/genes10010019","article-title":"Roles of elongator dependent tRNA modification pathways in neurodegeneration and cancer","volume":"10","author":"Hawer","year":"2018","journal-title":"Genes (Basel)"},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib19","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.ajhg.2019.03.026","article-title":"Recessive truncating mutations in ALKBH8 cause intellectual disability and severe impairment of wobble uridine modification","volume":"104","author":"Monies","year":"2019","journal-title":"Am. J. Hum. Genet."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib20","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/wrna.79","article-title":"RNA nucleotide methylation","volume":"2","author":"Motorin","year":"2011","journal-title":"Wiley. Interdiscip. Rev. RNA"},{"issue":"14","key":"10.1016\/j.abb.2021.109083_bib21","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1038\/onc.2015.244","article-title":"TRM6\/61 connects PKCalpha with translational control through tRNAi(Met) stabilization: impact on tumorigenesis","volume":"35","author":"Macari","year":"2016","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jmb.2006.11.046","article-title":"tRNA's wobble decoding of the genome: 40 years of modification","volume":"366","author":"Agris","year":"2007","journal-title":"J. Mol. Biol."},{"issue":"22","key":"10.1016\/j.abb.2021.109083_bib23","doi-asserted-by":"crossref","first-page":"8078","DOI":"10.1021\/bi050343f","article-title":"Structural effects of hypermodified nucleosides in the Escherichia coli and human tRNALys anticodon loop: the effect of nucleosides s2U, mcm5U, mcm5s2U, mnm5s2U, t6A, and ms2t6A","volume":"44","author":"Durant","year":"2005","journal-title":"Biochem."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib24","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41523-020-00211-7","article-title":"Circulating tRNA-derived small RNAs (tsRNAs) signature for the diagnosis and prognosis of breast cancer","volume":"7","author":"Wang","year":"2021","journal-title":"NPJ Breast Cancer"},{"issue":"30","key":"10.1016\/j.abb.2021.109083_bib25","doi-asserted-by":"crossref","first-page":"8071","DOI":"10.1073\/pnas.1706908114","article-title":"tsRNA signatures in cancer","volume":"114","author":"Balatti","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib26","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.cub.2006.04.027","article-title":"The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors","volume":"16","author":"Frye","year":"2006","journal-title":"Curr. Biol."},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib27","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1007\/s00109-019-01830-9","article-title":"METTL1 overexpression is correlated with poor prognosis and promotes hepatocellular carcinoma via PTEN","volume":"97","author":"Tian","year":"2019","journal-title":"J. Mol. Med."},{"issue":"35","key":"10.1016\/j.abb.2021.109083_bib28","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aaz4551","article-title":"METTL6 is a tRNA m(3)C methyltransferase that regulates pluripotency and tumor cell growth","volume":"6","author":"Ignatova","year":"2020","journal-title":"Sci. Adv."},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib29","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aas9184","article-title":"Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression","volume":"4","author":"Gu","year":"2018","journal-title":"Sci. Adv."},{"issue":"18","key":"10.1016\/j.abb.2021.109083_bib30","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21186707","article-title":"Functional characterization of a putative RNA demethylase ALKBH6 in arabidopsis growth and abiotic stress responses","volume":"21","author":"Huong","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib31","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20210337","article-title":"Genetic characteristics and prognostic implications of m1A regulators in pancreatic cancer","volume":"41","author":"Zheng","year":"2021","journal-title":"Biosci. Rep."},{"issue":"17","key":"10.1016\/j.abb.2021.109083_bib32","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1101\/gad.1956510","article-title":"tRNA biology charges to the front","volume":"24","author":"Phizicky","year":"2010","journal-title":"Genes Dev."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib33","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.bbagrm.2017.12.003","article-title":"Cooperativity between different tRNA modifications and their modification pathways","volume":"1861","author":"Sokolowski","year":"2018","journal-title":"Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms"},{"issue":"D1","key":"10.1016\/j.abb.2021.109083_bib34","doi-asserted-by":"crossref","first-page":"D303","DOI":"10.1093\/nar\/gkx1030","article-title":"MODOMICS: a database of RNA modification pathways. 2017 update","volume":"46","author":"Boccaletto","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib35","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1261\/rna.067736.118","article-title":"A rationale for tRNA modification circuits in the anticodon loop","volume":"24","author":"Han","year":"2018","journal-title":"RNA"},{"issue":"12","key":"10.1016\/j.abb.2021.109083_bib36","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1261\/rna.1738409","article-title":"Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs","volume":"15","author":"Cole","year":"2009","journal-title":"RNA"},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/genes9050246","article-title":"tRNA-derived small RNA: a novel regulatory small non-coding RNA","volume":"9","author":"Li","year":"2018","journal-title":"Genes"},{"issue":"8","key":"10.1016\/j.abb.2021.109083_bib38","doi-asserted-by":"crossref","DOI":"10.3390\/cells9081758","article-title":"The RNA methyltransferase NSUN2 and its potential roles in cancer","volume":"9","author":"Chellamuthu","year":"2020","journal-title":"Cells"},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib39","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1089\/dna.2020.5624","article-title":"m(1)A regulator TRMT10C predicts poorer survival and contributes to malignant behavior in gynecological cancers","volume":"39","author":"Wang","year":"2020","journal-title":"DNA Cell Biol."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib40","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s13073-015-0180-0","article-title":"The oxidative demethylase ALKBH3 marks hyperactive gene promoters in human cancer cells","volume":"7","author":"Liefke","year":"2015","journal-title":"Genome Med."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib41","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.dnarep.2006.10.005","article-title":"Repair of alkylated DNA: recent advances","volume":"6","author":"Sedgwick","year":"2007","journal-title":"DNA Repair (Amst)"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib42","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s00018-020-03594-9","article-title":"Multi-substrate selectivity based on key loops and non-homologous domains: new insight into ALKBH family","volume":"78","author":"Xu","year":"2021","journal-title":"Cell. Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib43","doi-asserted-by":"crossref","first-page":"2782","DOI":"10.1038\/s41467-019-10669-0","article-title":"m(6)A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade","volume":"10","author":"Yang","year":"2019","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib44","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.cell.2016.09.038","article-title":"ALKBH1-Mediated tRNA demethylation regulates translation","volume":"167","author":"Liu","year":"2016","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib45","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1093\/nar\/gky1250","article-title":"Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs","volume":"47","author":"Chen","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib46","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/s41556-021-00709-7","article-title":"ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing","volume":"23","author":"Zhang","year":"2021","journal-title":"Nat. Cell Biol."},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib47","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1128\/MCB.01602-09","article-title":"Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding","volume":"30","author":"Songe-Moller","year":"2010","journal-title":"Mol. Cell Biol."},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib48","first-page":"155","article-title":"Reversible RNA Modification N-1 - methyladenosine (m(1)A) in mRNA and tRNA","volume":"16","author":"Zhang","year":"2018","journal-title":"Dev. Reprod. Biol."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib49","doi-asserted-by":"crossref","DOI":"10.3390\/biom7010020","article-title":"m1A Post-Transcriptional Modification in tRNAs","volume":"7","author":"Oerum","year":"2017","journal-title":"Biomolecules"},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib50","doi-asserted-by":"crossref","first-page":"6157","DOI":"10.1093\/nar\/gkaa353","article-title":"Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B","volume":"48","author":"Vilardo","year":"2020","journal-title":"Nucleic Acids Res."},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib51","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1261\/rna.072090.119","article-title":"Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B","volume":"25","author":"Howell","year":"2019","journal-title":"RNA"},{"issue":"21","key":"10.1016\/j.abb.2021.109083_bib52","doi-asserted-by":"crossref","first-page":"12469","DOI":"10.1093\/nar\/gkx902","article-title":"The MRPP1\/MRPP2 complex is a tRNA-maturation platform in human mitochondria","volume":"45","author":"Reinhard","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib53","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.cell.2008.09.013","article-title":"RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme","volume":"135","author":"Holzmann","year":"2008","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib54","doi-asserted-by":"crossref","first-page":"3252","DOI":"10.1093\/nar\/gkn169","article-title":"The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK)","volume":"36","author":"Roovers","year":"2008","journal-title":"Nucleic Acids Res."},{"issue":"9","key":"10.1016\/j.abb.2021.109083_bib55","doi-asserted-by":"crossref","first-page":"4736","DOI":"10.1093\/nar\/gkz230","article-title":"Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition","volume":"47","author":"Degut","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib56","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s12104-016-9680-0","article-title":"Backbone resonance assignments of the m1A22 tRNA methyltransferase TrmK from Bacillus subtilis","volume":"10","author":"Degut","year":"2016","journal-title":"Biomol. NMR. Assign"},{"issue":"8","key":"10.1016\/j.abb.2021.109083_bib57","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/S0300-9084(02)01446-3","article-title":"RNA editing by adenosine deaminases generates RNA and protein diversity","volume":"84","author":"Schaub","year":"2002","journal-title":"Biochimie"},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib58","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1261\/rna.037507.112","article-title":"Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells","volume":"19","author":"Pavon-Eternod","year":"2013","journal-title":"RNA"},{"issue":"4\u20135","key":"10.1016\/j.abb.2021.109083_bib59","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1080\/15476286.2017.1371402","article-title":"The role of intracellular compartmentalization on tRNA processing and modification","volume":"15","author":"Kessler","year":"2018","journal-title":"RNA Biol."},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib60","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1017\/S1355838202024019","article-title":"Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA","volume":"8","author":"Alexandrov","year":"2002","journal-title":"RNA"},{"issue":"21","key":"10.1016\/j.abb.2021.109083_bib61","doi-asserted-by":"crossref","DOI":"10.1128\/MCB.00214-17","article-title":"TRMT1-Catalyzed tRNA modifications are required for redox homeostasis to ensure proper cellular proliferation and oxidative stress survival","volume":"37","author":"Dewe","year":"2017","journal-title":"Mol. Cell Biol."},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib62","doi-asserted-by":"crossref","first-page":"5195","DOI":"10.1093\/nar\/gky156","article-title":"SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function","volume":"46","author":"Du","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"21","key":"10.1016\/j.abb.2021.109083_bib63","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00448-19","article-title":"Distinct modified nucleosides in tRNA(Trp) from the hyperthermophilic archaeon thermococcus kodakarensis and requirement of tRNA m(2)G10\/m(2) 2G10 methyltransferase (archaeal Trm11) for survival at high temperatures","volume":"201","author":"Hirata","year":"2019","journal-title":"J. Bacteriol."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib64","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1038\/s41598-019-38550-6","article-title":"Identification of recurrent fusion genes across multiple cancer types","volume":"9","author":"Yu","year":"2019","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.abb.2021.109083_bib65","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19124080","article-title":"7-Methylguanosine modifications in transfer RNA (tRNA)","volume":"19","author":"Tomikawa","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.abb.2021.109083_bib66","doi-asserted-by":"crossref","first-page":"42271","DOI":"10.1038\/srep42271","article-title":"AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells","volume":"7","author":"Ueda","year":"2017","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib67","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1101\/gad.215533.113","article-title":"Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis","volume":"27","author":"Fu","year":"2013","journal-title":"Genes Dev."},{"issue":"35","key":"10.1016\/j.abb.2021.109083_bib68","doi-asserted-by":"crossref","first-page":"14695","DOI":"10.1074\/jbc.M117.798298","article-title":"Three distinct 3-methylcytidine (m(3)C) methyltransferases modify tRNA and mRNA in mice and humans","volume":"292","author":"Xu","year":"2017","journal-title":"J. Biol. Chem."},{"issue":"14","key":"10.1016\/j.abb.2021.109083_bib69","doi-asserted-by":"crossref","first-page":"8309","DOI":"10.1093\/nar\/gkab603","article-title":"Mutually exclusive substrate selection strategy by human m3C RNA transferases METTL2A and METTL6","volume":"49","author":"Mao","year":"2021","journal-title":"Nucleic Acids Res."},{"issue":"35","key":"10.1016\/j.abb.2021.109083_bib70","doi-asserted-by":"crossref","first-page":"eaaz4551","DOI":"10.1126\/sciadv.aaz4551","article-title":"METTL6 is a tRNA m(3)C methyltransferase that regulates pluripotency and tumor cell growth","volume":"6","author":"Ignatova","year":"2020","journal-title":"Sci. Adv."},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib71","doi-asserted-by":"crossref","DOI":"10.3390\/genes10020102","article-title":"Eukaryotic 5-methylcytosine (m(5)C) RNA methyltransferases: mechanisms, cellular functions, and links to disease","volume":"10","author":"Bohnsack","year":"2019","journal-title":"Genes (Basel)"},{"issue":"12","key":"10.1016\/j.abb.2021.109083_bib72","doi-asserted-by":"crossref","first-page":"7401","DOI":"10.1093\/nar\/gkx354","article-title":"ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications","volume":"45","author":"Kawarada","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib73","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/nchembio.2099","article-title":"NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNA(Met)","volume":"12","author":"Nakano","year":"2016","journal-title":"Nat. Chem. Biol."},{"issue":"27","key":"10.1016\/j.abb.2021.109083_bib74","doi-asserted-by":"crossref","first-page":"10964","DOI":"10.1073\/pnas.1222641110","article-title":"Expanded use of sense codons is regulated by modified cytidines in tRNA","volume":"110","author":"Cantara","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"18","key":"10.1016\/j.abb.2021.109083_bib75","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.15252\/embj.201489282","article-title":"Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders","volume":"33","author":"Blanco","year":"2014","journal-title":"EMBO J."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib76","doi-asserted-by":"crossref","DOI":"10.3390\/biom7010029","article-title":"Chemical and conformational diversity of modified nucleosides affects tRNA structure and function","volume":"7","author":"Vare","year":"2017","journal-title":"Biomolecules"},{"issue":"8","key":"10.1016\/j.abb.2021.109083_bib77","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1261\/rna.970408","article-title":"Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism","volume":"14","author":"Jurkowski","year":"2008","journal-title":"RNA"},{"key":"10.1016\/j.abb.2021.109083_bib78","first-page":"1","article-title":"New substrates and determinants for tRNA recognition of RNA methyltransferase DNMT2\/TRDMT1","author":"Li","year":"2021","journal-title":"RNA Biol."},{"issue":"18","key":"10.1016\/j.abb.2021.109083_bib79","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.15252\/embj.201591382","article-title":"The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis","volume":"34","author":"Tuorto","year":"2015","journal-title":"EMBO J."},{"issue":"9","key":"10.1016\/j.abb.2021.109083_bib80","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1261\/rna.051524.115","article-title":"NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs","volume":"21","author":"Haag","year":"2015","journal-title":"RNA"},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib81","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1093\/nar\/gkaa1193","article-title":"Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6","volume":"49","author":"Selmi","year":"2021","journal-title":"Nucleic Acids Res."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib82","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1080\/15476286.2020.1712544","article-title":"TRMT2B is responsible for both tRNA and rRNA m(5)U-methylation in human mitochondria","volume":"17","author":"Powell","year":"2020","journal-title":"RNA Biol."},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib83","doi-asserted-by":"crossref","first-page":"5023","DOI":"10.1093\/nar\/gks144","article-title":"Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA","volume":"40","author":"Squires","year":"2012","journal-title":"Nucleic Acids Res."},{"issue":"19","key":"10.1016\/j.abb.2021.109083_bib84","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1093\/nar\/gkz658","article-title":"FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA","volume":"47","author":"Carter","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib85","doi-asserted-by":"crossref","DOI":"10.3390\/genes12020140","article-title":"Post-transcriptional modifications of conserved nucleotides in the T-loop of tRNA: a tale of functional convergent evolution","volume":"12","author":"Roovers","year":"2021","journal-title":"Genes"},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib86","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/s41589-019-0420-5","article-title":"Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation","volume":"16","author":"Song","year":"2020","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.abb.2021.109083_bib87","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/bs.enz.2017.02.001","article-title":"Posttranscriptional RNA pseudouridylation","volume":"41","author":"De Zoysa","year":"2017","journal-title":"Enzymes"},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib88","doi-asserted-by":"crossref","DOI":"10.1002\/wrna.1595","article-title":"Naturally occurring modified ribonucleosides","volume":"11","author":"McCown","year":"2020","journal-title":"Wiley. Interdiscipl. Rev. RNA"},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib89","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/molbev\/msy245","article-title":"The expansion of inosine at the wobble position of tRNAs, and its role in the evolution of proteomes","volume":"36","author":"Rafels-Ybern","year":"2019","journal-title":"Mol. Biol. Evol."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib90","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1073\/pnas.1014402108","article-title":"Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier","volume":"108","author":"Van der Veen","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib91","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1084\/jem.20160397","article-title":"Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer","volume":"213","author":"Delaunay","year":"2016","journal-title":"J. Exp. Med."},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib92","doi-asserted-by":"crossref","first-page":"e0131335","DOI":"10.1371\/journal.pone.0131335","article-title":"Alkbh8 regulates selenocysteine-protein expression to protect against reactive oxygen species damage","volume":"10","author":"Endres","year":"2015","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib93","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/emmm.201201161","article-title":"A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-alpha","volume":"5","author":"Begley","year":"2013","journal-title":"EMBO Mol. Med."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib94","doi-asserted-by":"crossref","first-page":"2816","DOI":"10.1093\/nar\/gkab104","article-title":"The human tRNA taurine modification enzyme GTPBP3 is an active GTPase linked to mitochondrial diseases","volume":"49","author":"Peng","year":"2021","journal-title":"Nucleic Acids Res."},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib95","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1093\/nar\/gkaa093","article-title":"Molecular basis for t6A modification in human mitochondria","volume":"48","author":"Zhou","year":"2020","journal-title":"Nucleic Acids Res."},{"issue":"17","key":"10.1016\/j.abb.2021.109083_bib96","doi-asserted-by":"crossref","first-page":"13666","DOI":"10.1074\/jbc.M112.344028","article-title":"Biosynthesis of threonylcarbamoyl adenosine (t6A), a universal tRNA nucleoside","volume":"287","author":"Deutsch","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"9","key":"10.1016\/j.abb.2021.109083_bib97","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1261\/rna.075747.120","article-title":"Specificity in the biosynthesis of the universal tRNA nucleoside N (6)-threonylcarbamoyl adenosine (t(6)A)-TsaD is the gatekeeper","volume":"26","author":"Swinehart","year":"2020","journal-title":"RNA"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib98","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1038\/s41467-019-14004-5","article-title":"Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification","volume":"11","author":"Santos","year":"2020","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib99","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1002\/humu.23196","article-title":"Matchmaking facilitates the diagnosis of an autosomal-recessive mitochondrial disease caused by biallelic mutation of the tRNA isopentenyltransferase (TRIT1) gene","volume":"38","author":"Kernohan","year":"2017","journal-title":"Hum. Mutat."},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib100","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.cmet.2015.01.019","article-title":"Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans","volume":"21","author":"Wei","year":"2015","journal-title":"Cell Metabol."},{"key":"10.1016\/j.abb.2021.109083_bib101","series-title":"The Occurrence Order and Cross-Talk of Different tRNA Modifications","author":"Li","year":"2021"},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib102","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/cge.13443","article-title":"A null variant in PUS3 confirms its involvement in intellectual disability and further delineates the associated neurodevelopmental disease","volume":"94","author":"Abdelrahman","year":"2018","journal-title":"Clin. Genet."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib103","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1021\/acs.biochem.8b01047","article-title":"A family divided: distinct structural and mechanistic features of the SpoU-TrmD (SPOUT) methyltransferase superfamily","volume":"58","author":"Krishnamohan","year":"2019","journal-title":"Biochem."},{"key":"10.1016\/j.abb.2021.109083_bib104","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/1471-2407-10-108","article-title":"The expression of TRMT2A, a novel cell cycle regulated protein, identifies a subset of breast cancer patients with HER2 over-expression that are at an increased risk of recurrence","volume":"10","author":"Hicks","year":"2010","journal-title":"BMC Cancer"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib105","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1186\/s12957-020-02106-0","article-title":"ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-kappaB pathway","volume":"18","author":"Ke","year":"2020","journal-title":"World J. Surg. Oncol."},{"key":"10.1016\/j.abb.2021.109083_bib106","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.00293","article-title":"ALKBH4 functions as a suppressor of colorectal cancer metastasis via competitively binding to WDR5","volume":"8","author":"Shen","year":"2020","journal-title":"Front. Cell. Dev. Biol."},{"key":"10.1016\/j.abb.2021.109083_bib107","doi-asserted-by":"crossref","first-page":"114284","DOI":"10.1016\/j.bcp.2020.114284","article-title":"ALKBH1 promotes lung cancer by regulating m6A RNA demethylation","volume":"189","author":"Li","year":"2021","journal-title":"Biochem. Pharmacol."},{"issue":"19","key":"10.1016\/j.abb.2021.109083_bib108","doi-asserted-by":"crossref","first-page":"5247","DOI":"10.1158\/1078-0432.CCR-12-0955","article-title":"ALKBH3 contributes to survival and angiogenesis of human urothelial carcinoma cells through NADPH oxidase and tweak\/Fn14\/VEGF signals","volume":"18","author":"Shimada","year":"2012","journal-title":"Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib109","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.ajhg.2016.06.013","article-title":"Recessive mutations in TRMT10C cause defects in mitochondrial RNA processing and multiple respiratory chain deficiencies","volume":"99","author":"Metodiev","year":"2016","journal-title":"Am. J. Hum. Genet."},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib110","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1261\/rna.047910.114","article-title":"WBSCR22\/Merm1 is required for late nuclear pre-ribosomal RNA processing and mediates N7-methylation of G1639 in human 18S rRNA","volume":"21","author":"Haag","year":"2015","journal-title":"RNA"},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib111","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.molcel.2019.03.040","article-title":"METTL1 promotes let-7 MicroRNA processing via m7G methylation","volume":"74","author":"Pandolfini","year":"2019","journal-title":"Mol. Cell"},{"key":"10.1016\/j.abb.2021.109083_bib112","doi-asserted-by":"crossref","first-page":"117480","DOI":"10.1016\/j.lfs.2020.117480","article-title":"Methyltransferase-like 1 (METTL1) served as a tumor suppressor in colon cancer by activating 7-methyguanosine (m7G) regulated let-7e miRNA\/HMGA2 axis","volume":"249","author":"Liu","year":"2020","journal-title":"Life Sci."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib113","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3892\/ol.2021.12591","article-title":"Methyltransferase-like 1 regulates lung adenocarcinoma A549 cell proliferation and autophagy via the AKT\/mTORC1 signaling pathway","volume":"21","author":"Wang","year":"2021","journal-title":"Oncol Lett"},{"issue":"16","key":"10.1016\/j.abb.2021.109083_bib114","doi-asserted-by":"crossref","first-page":"3339","DOI":"10.1016\/j.molcel.2021.07.003","article-title":"N(7)-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression","volume":"81","author":"Dai","year":"2021","journal-title":"Mol. Cell"},{"issue":"21","key":"10.1016\/j.abb.2021.109083_bib115","article-title":"METTL1\/WDR4 mediated m(7)G tRNA modifications and m(7)G codon usage promote mRNA translation and lung cancer progression","volume":"S1525-0016","author":"Ma","year":"2021","journal-title":"Mol. Ther."},{"issue":"16","key":"10.1016\/j.abb.2021.109083_bib116","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1016\/j.molcel.2021.06.031","article-title":"METTL1-mediated m(7)G modification of Arg-TCT tRNA drives oncogenic transformation","volume":"81","author":"Orellana","year":"2021","journal-title":"Mol. Cell"},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib117","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.molcel.2018.06.001","article-title":"Mettl1\/Wdr4-Mediated m(7)G tRNA methylome is required for normal mRNA translation and embryonic stem cell self-renewal and differentiation","volume":"71","author":"Lin","year":"2018","journal-title":"Mol. Cell"},{"issue":"18","key":"10.1016\/j.abb.2021.109083_bib118","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.15252\/embj.201489282","article-title":"Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders","volume":"33","author":"Blanco","year":"2014","journal-title":"EMBO J."},{"issue":"12","key":"10.1016\/j.abb.2021.109083_bib119","first-page":"1143","article-title":"NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation","volume":"7","author":"Tang","year":"2015","journal-title":"Aging (N Y)"},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib120","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1089\/dna.2011.1446","article-title":"Frequent increased gene copy number and high protein expression of tRNA (cytosine-5-)-methyltransferase (NSUN2) in human cancers","volume":"31","author":"Okamoto","year":"2012","journal-title":"DNA Cell Biol."},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib121","doi-asserted-by":"crossref","first-page":"3510","DOI":"10.1111\/cas.14190","article-title":"NOP2\/Sun RNA methyltransferase 2 promotes tumor progression via its interacting partner RPL6 in gallbladder carcinoma","volume":"110","author":"Gao","year":"2019","journal-title":"Cancer Sci."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib122","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41419-020-2487-z","article-title":"RNA methyltransferase NSUN2 promotes gastric cancer cell proliferation by repressing p57(Kip2) by an m(5)C-dependent manner","volume":"11","author":"Mei","year":"2020","journal-title":"Cell Death Dis."},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib123","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.bbrc.2018.11.104","article-title":"TRMT2A is a novel cell cycle regulator that suppresses cell proliferation","volume":"508","author":"Chang","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib124","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/ajmg.b.30638","article-title":"A loss-of-function mutation in the FTSJ1 gene causes nonsyndromic X-linked mental retardation in a Japanese family","volume":"147B","author":"Takano","year":"2008","journal-title":"Am. J. Med. Genet B. Neuropsychiatr. Genet"},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib125","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1086\/422507","article-title":"Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine-binding protein cause nonsyndromic X-linked mental retardation","volume":"75","author":"Freude","year":"2004","journal-title":"Am. J. Hum. Genet."},{"issue":"13","key":"10.1016\/j.abb.2021.109083_bib126","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abf3072","article-title":"Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability","volume":"7","author":"Nagayoshi","year":"2021","journal-title":"Sci. Adv."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib127","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/s41419-020-2525-x","article-title":"FTSJ1 regulates tRNA 2'-O-methyladenosine modification and suppresses the malignancy of NSCLC via inhibiting DRAM1 expression","volume":"11","author":"He","year":"2020","journal-title":"Cell Death Dis."},{"issue":"8","key":"10.1016\/j.abb.2021.109083_bib128","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1080\/15476286.2020.1779492","article-title":"The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation","volume":"17","author":"Rashad","year":"2020","journal-title":"RNA Biol."},{"key":"10.1016\/j.abb.2021.109083_bib129","doi-asserted-by":"crossref","first-page":"104449","DOI":"10.1016\/j.yexmp.2020.104449","article-title":"MiRNA-339-5p suppresses the malignant development of gastric cancer via targeting ALKBH1","volume":"115","author":"Wang","year":"2020","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.abb.2021.109083_bib130","first-page":"476","article-title":"A real-time PCR-based quantitative assay for 3-methylcytosine demethylase activity of ALKBH3","volume":"5","author":"Ueda","year":"2016","journal-title":"Biochem Biophys Rep"},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib131","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1182\/blood.2020005823","article-title":"Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome","volume":"137","author":"Esteve-Puig","year":"2021","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib132","doi-asserted-by":"crossref","first-page":"648","DOI":"10.3892\/or.2015.4017","article-title":"Clinical significance and therapeutic potential of prostate cancer antigen-1\/ALKBH3 in human renal cell carcinoma","volume":"34","author":"Hotta","year":"2015","journal-title":"Oncol. Rep."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib133","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.bmcl.2014.01.008","article-title":"Design and synthesis of prostate cancer antigen-1 (PCA-1\/ALKBH3) inhibitors as anti-prostate cancer drugs","volume":"24","author":"Nakao","year":"2014","journal-title":"Bioorg. Med. Chem. Lett"},{"key":"10.1016\/j.abb.2021.109083_bib134","doi-asserted-by":"crossref","DOI":"10.1111\/jgh.14117","article-title":"Association of AlkB homolog 3 expression with tumor recurrence and unfavorable prognosis in hepatocellular carcinoma","author":"Wang","year":"2018","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"18","key":"10.1016\/j.abb.2021.109083_bib135","doi-asserted-by":"crossref","first-page":"4829","DOI":"10.1158\/0008-5472.CAN-12-0328","article-title":"PCA-1\/ALKBH3 contributes to pancreatic cancer by supporting apoptotic resistance and angiogenesis","volume":"72","author":"Yamato","year":"2012","journal-title":"Cancer Res."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib136","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/sj.bjc.6606012","article-title":"ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer","volume":"104","author":"Tasaki","year":"2011","journal-title":"Br. J. Cancer"},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib137","doi-asserted-by":"crossref","first-page":"e1005345","DOI":"10.1371\/journal.pcbi.1005345","article-title":"ALKBH7 variant related to prostate cancer exhibits altered substrate binding","volume":"13","author":"Walker","year":"2017","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.abb.2021.109083_bib138","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.semcdb.2017.05.023","article-title":"ROS signalling in the biology of cancer","volume":"80","author":"Moloney","year":"2018","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.abb.2021.109083_bib139","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.taap.2018.06.003","article-title":"Roles of ROS, Nrf2, and autophagy in cadmium-carcinogenesis and its prevention by sulforaphane","volume":"353","author":"Wang","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.abb.2021.109083_bib140","first-page":"163","article-title":"Oxidative stress, and metastasis","volume":"81","author":"Gill","year":"2016","journal-title":"Targeting. Cancer"},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib141","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.bbrc.2016.06.084","article-title":"ALKBH8 promotes bladder cancer growth and progression through regulating the expression of survivin","volume":"477","author":"Ohshio","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib142","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1158\/0008-5472.CAN-08-3530","article-title":"A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression","volume":"69","author":"Shimada","year":"2009","journal-title":"Cancer Res."},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib143","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.bbrc.2016.06.084","article-title":"ALKBH8 promotes bladder cancer growth and progression through regulating the expression of survivin","volume":"477","author":"Ohshio","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib144","doi-asserted-by":"crossref","first-page":"13249","DOI":"10.1038\/s41598-019-49550-x","article-title":"ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy","volume":"9","author":"Pilzys","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.abb.2021.109083_bib145","doi-asserted-by":"crossref","first-page":"103195","DOI":"10.1016\/j.ebiom.2020.103195","article-title":"The RNA methyltransferase NSUN6 suppresses pancreatic cancer development by regulating cell proliferation","volume":"63","author":"Yang","year":"2021","journal-title":"EBioMedicine"},{"issue":"22","key":"10.1016\/j.abb.2021.109083_bib146","first-page":"11729","article-title":"Human RAD51 paralogue RAD51C fosters repair of alkylated DNA by interacting with the ALKBH3 demethylase","volume":"47","author":"Mohan","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.abb.2021.109083_bib147","doi-asserted-by":"crossref","first-page":"635808","DOI":"10.3389\/fgene.2021.635808","article-title":"Human ALKBH6 is required for maintenance of genomic stability and promoting cell survival during exposure of alkylating agents in pancreatic cancer","volume":"12","author":"Zhao","year":"2021","journal-title":"Front. Genet."},{"issue":"13","key":"10.1016\/j.abb.2021.109083_bib148","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1038\/onc.2015.216","article-title":"MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies","volume":"35","author":"Hessmann","year":"2016","journal-title":"Oncogene"},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib149","first-page":"2169","article-title":"Expression and significance of m1A transmethylase, hTrm6p\/hTrm61p and its related gene hTrm6\/hTrm61 in bladder urothelial carcinoma","volume":"5","author":"Shi","year":"2015","journal-title":"Am J Cancer Res"},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib150","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/bjc.2017.421","article-title":"MTOR inhibitor-based combination therapies for pancreatic cancer","volume":"118","author":"Hassan","year":"2018","journal-title":"Br. J. Cancer"},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib151","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.cub.2006.04.027","article-title":"The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors","volume":"16","author":"Frye","year":"2006","journal-title":"Curr. Biol."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib152","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1083\/jcb.200810180","article-title":"The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability","volume":"186","author":"Hussain","year":"2009","journal-title":"J. Cell Biol."},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib153","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1091\/mbc.e06-11-1021","article-title":"Aurora-B regulates RNA methyltransferase NSUN2","volume":"18","author":"Sakita-Suto","year":"2007","journal-title":"Mol. Biol. Cell"},{"issue":"9","key":"10.1016\/j.abb.2021.109083_bib154","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/nsmb.2357","article-title":"RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis","volume":"19","author":"Tuorto","year":"2012","journal-title":"Nat. Struct. Mol. Biol."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib155","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.molcel.2016.02.011","article-title":"Mitochondria and cancer","volume":"61","author":"Zong","year":"2016","journal-title":"Mol. Cell"},{"key":"10.1016\/j.abb.2021.109083_bib156","doi-asserted-by":"crossref","first-page":"599340","DOI":"10.3389\/fmolb.2020.599340","article-title":"m(5)C RNA methylation primarily affects the ErbB and PI3K-akt signaling pathways in gastrointestinal cancer","volume":"7","author":"Xiang","year":"2020","journal-title":"Front. Mol. Biosci"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib157","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1186\/s13046-019-1470-y","article-title":"Up-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K\/Akt signaling pathway","volume":"38","author":"Xu","year":"2019","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib158","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1053\/j.gastro.2020.07.046","article-title":"Loss of HIF1A from pancreatic cancer cells increases expression of PPP1R1B and degradation of p53 to promote invasion and metastasis","volume":"159","author":"Tiwari","year":"2020","journal-title":"Gastroenterology"},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib159","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1136\/gutjnl-2014-307075","article-title":"SOX9 regulates ERBB signalling in pancreatic cancer development","volume":"64","author":"Grimont","year":"2015","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib160","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1186\/s13046-018-0947-4","article-title":"LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer","volume":"37","author":"Feng","year":"2018","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.abb.2021.109083_bib161","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.omto.2020.03.006","article-title":"Overexpression of YBX1 promotes pancreatic ductal adenocarcinoma growth via the GSK3B\/cyclin D1\/cyclin E1 pathway","volume":"17","author":"Liu","year":"2020","journal-title":"Mol. Ther. Oncolytics."},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib162","doi-asserted-by":"crossref","first-page":"118659","DOI":"10.1016\/j.bbamcr.2020.118659","article-title":"GSK-3beta in DNA repair, apoptosis, and resistance of chemotherapy, radiotherapy of cancer","volume":"1867","author":"Lin","year":"2020","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"issue":"8","key":"10.1016\/j.abb.2021.109083_bib163","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1097\/CAD.0000000000000948","article-title":"HOXB5 promotes proliferation, migration, and invasion of pancreatic cancer cell through the activation of the GSK3beta\/beta-catenin pathway","volume":"31","author":"Gao","year":"2020","journal-title":"Anti Cancer Drugs"},{"issue":"13","key":"10.1016\/j.abb.2021.109083_bib164","doi-asserted-by":"crossref","first-page":"5638","DOI":"10.1158\/0008-5472.CAN-05-0600","article-title":"A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis","volume":"65","author":"Kato","year":"2005","journal-title":"Cancer Res."},{"issue":"17","key":"10.1016\/j.abb.2021.109083_bib165","doi-asserted-by":"crossref","first-page":"5801","DOI":"10.1158\/1078-0432.CCR-11-1133","article-title":"Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy","volume":"17","author":"Tan","year":"2011","journal-title":"Clin. Cancer Res."},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib166","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22062941","article-title":"m(5)U54 tRNA hypomodification by lack of TRMT2A drives the generation of tRNA-derived small RNAs","volume":"22","author":"Pereira","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib167","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/s41392-020-00217-4","article-title":"Action mechanisms and research methods of tRNA-derived small RNAs","volume":"5","author":"Xie","year":"2020","journal-title":"Signal. Transduct. Target Ther."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib168","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/s12943-019-1000-8","article-title":"Exosomal tRNA-derived small RNA as a promising biomarker for cancer diagnosis","volume":"18","author":"Zhu","year":"2019","journal-title":"Mol. Cancer"},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib169","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s12943-021-01389-5","article-title":"A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer","volume":"20","author":"Jin","year":"2021","journal-title":"Mol. Cancer"},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib170","first-page":"837","article-title":"Serum tRNA-derived small RNAs as potential novel diagnostic biomarkers for pancreatic ductal adenocarcinoma","volume":"11","author":"Xue","year":"2021","journal-title":"Am J Cancer Res"},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib171","first-page":"3104","article-title":"Expression profile of tRNA-derived fragments in pancreatic cancer","volume":"18","author":"Jin","year":"2019","journal-title":"Oncol Lett"},{"issue":"5","key":"10.1016\/j.abb.2021.109083_bib172","doi-asserted-by":"crossref","first-page":"e23742","DOI":"10.1002\/jcla.23742","article-title":"Low expression of tRF-Pro-CGG predicts poor prognosis in pancreatic ductal adenocarcinoma","volume":"35","author":"Li","year":"2021","journal-title":"J. Clin. Lab. Anal."},{"issue":"7683","key":"10.1016\/j.abb.2021.109083_bib173","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature25005","article-title":"A transfer-RNA-derived small RNA regulates ribosome biogenesis","volume":"552","author":"Kim","year":"2017","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.abb.2021.109083_bib174","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1093\/carcin\/bgt330","article-title":"miR-720 inhibits tumor invasion and migration in breast cancer by targeting TWIST1","volume":"35","author":"Li","year":"2014","journal-title":"Carcinogenesis"},{"issue":"12","key":"10.1016\/j.abb.2021.109083_bib175","doi-asserted-by":"crossref","DOI":"10.3390\/biom10121625","article-title":"Recent development of aminoacyl-tRNA synthetase inhibitors for human diseases: a future perspective","volume":"10","author":"Kim","year":"2020","journal-title":"Biomolecules"},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib176","doi-asserted-by":"crossref","DOI":"10.3390\/genes11111384","article-title":"Multi-omics database analysis of aminoacyl-tRNA synthetases in cancer","volume":"11","author":"Wang","year":"2020","journal-title":"Genes (Basel)"},{"issue":"26","key":"10.1016\/j.abb.2021.109083_bib177","doi-asserted-by":"crossref","first-page":"21979","DOI":"10.18632\/oncotarget.4273","article-title":"Overexpressed tryptophanyl-tRNA synthetase, an angiostatic protein, enhances oral cancer cell invasiveness","volume":"6","author":"Lee","year":"2015","journal-title":"Oncotarget"},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib178","doi-asserted-by":"crossref","first-page":"E640","DOI":"10.1073\/pnas.1200194109","article-title":"Secreted human glycyl-tRNA synthetase implicated in defense against ERK-activated tumorigenesis","volume":"109","author":"Park","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib179","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.molmed.2014.02.007","article-title":"MUC1: a multifaceted oncoprotein with a key role in cancer progression","volume":"20","author":"Nath","year":"2014","journal-title":"Trends Mol. Med."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib180","doi-asserted-by":"crossref","first-page":"e424","DOI":"10.1038\/emm.2017.231","article-title":"Inhibition of MUC1 biosynthesis via threonyl-tRNA synthetase suppresses pancreatic cancer cell migration","volume":"50","author":"Jeong","year":"2018","journal-title":"Exp. Mol. Med."},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib181","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3233\/CBM-170297","article-title":"Decreased expression of MUC1 induces apoptosis and inhibits migration in pancreatic cancer PANC-1 cells via regulation of Slug pathway","volume":"20","author":"Zhao","year":"2017","journal-title":"Cancer Biomarkers"},{"issue":"6","key":"10.1016\/j.abb.2021.109083_bib182","doi-asserted-by":"crossref","first-page":"599","DOI":"10.4048\/jbc.2020.23.e67","article-title":"Tryptophanyl-tRNA synthetase sensitizes hormone receptor-positive breast cancer to docetaxel-based chemotherapy","volume":"23","author":"Lee","year":"2020","journal-title":"J. Breast. Cancer"},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib183","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1158\/1055-9965.EPI-09-0456","article-title":"The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer","volume":"18","author":"Ghanipour","year":"2009","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib184","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1073\/pnas.012602099","article-title":"A human aminoacyl-tRNA synthetase as a regulator of angiogenesis","volume":"99","author":"Wakasugi","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"7","key":"10.1016\/j.abb.2021.109083_bib185","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1097\/MPA.0b013e318222e635","article-title":"Hypoxia signature of splice forms of tryptophanyl-tRNA synthetase marks pancreatic cancer cells with distinct metastatic abilities","volume":"40","author":"Paley","year":"2011","journal-title":"Pancreas"},{"issue":"11","key":"10.1016\/j.abb.2021.109083_bib186","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1080\/15476286.2020.1722449","article-title":"RNA modifications and cancer","volume":"17","author":"Haruehanroengra","year":"2020","journal-title":"RNA Biol."},{"key":"10.1016\/j.abb.2021.109083_bib187","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.12659\/MSM.913556","article-title":"Clinical significance of TRMT6 in hepatocellular carcinoma: a bioinformatics-based study","volume":"25","author":"Wang","year":"2019","journal-title":"Med. Sci. Mon."},{"issue":"14","key":"10.1016\/j.abb.2021.109083_bib188","doi-asserted-by":"crossref","first-page":"5090","DOI":"10.1158\/1078-0432.CCR-05-0195","article-title":"High expression of a new marker PCA-1 in human prostate carcinoma","volume":"11","author":"Konishi","year":"2005","journal-title":"Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.abb.2021.109083_bib189","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.gene.2014.09.049","article-title":"The cytoplasmic and nuclear populations of the eukaryote tRNA-isopentenyl transferase have distinct functions with implications in human cancer","volume":"556","author":"Smaldino","year":"2015","journal-title":"Gene"},{"issue":"4","key":"10.1016\/j.abb.2021.109083_bib190","first-page":"4767","article-title":"CDK5RAP1 targeting NF-kappaB signaling pathway in human malignant melanoma A375 cell apoptosis","volume":"15","author":"Xiong","year":"2018","journal-title":"Oncol Lett"},{"issue":"3","key":"10.1016\/j.abb.2021.109083_bib191","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.3892\/or.2015.3736","article-title":"CDK5RAP1 deficiency induces cell cycle arrest and apoptosis in human breast cancer cell line by the ROS\/JNK signaling pathway","volume":"33","author":"Wang","year":"2015","journal-title":"Oncol. Rep."},{"issue":"24","key":"10.1016\/j.abb.2021.109083_bib192","first-page":"12328","article-title":"Overexpressed methyltransferase-like 1 (METTL1) increased chemosensitivity of colon cancer cells to cisplatin by regulating miR-149-3p\/S100A4\/p53 axis","volume":"11","author":"Liu","year":"2019","journal-title":"Aging (N Y)"},{"issue":"10","key":"10.1016\/j.abb.2021.109083_bib193","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1038\/ng.3073","article-title":"An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer","volume":"46","author":"Gatza","year":"2014","journal-title":"Nat. Genet."},{"issue":"19","key":"10.1016\/j.abb.2021.109083_bib194","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.15252\/embj.201694885","article-title":"NSUN3 and ABH1 modify the wobble position of mt-tRNA(Met) to expand codon recognition in mitochondrial translation","volume":"35","author":"Haag","year":"2016","journal-title":"EMBO J."},{"key":"10.1016\/j.abb.2021.109083_bib195","doi-asserted-by":"crossref","first-page":"12039","DOI":"10.1038\/ncomms12039","article-title":"Deficient methylation and formylation of mt- tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3","volume":"7","author":"Van Haute","year":"2016","journal-title":"Nat. Commun."}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986121003325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986121003325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T06:20:57Z","timestamp":1757744457000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986121003325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":195,"alternative-id":["S0003986121003325"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2021.109083","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"tRNA modifications and their potential roles in pancreatic cancer","name":"articletitle","label":"Article Title"},{"value":"Archives of Biochemistry and Biophysics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abb.2021.109083","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109083"}}