{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:56:25Z","timestamp":1792626985989,"version":"4.5.0"},"reference-count":84,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.abb.2022.109213","type":"journal-article","created":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T21:03:33Z","timestamp":1649538213000},"page":"109213","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Circadian control of kynurenine pathway enzymes in the rat pineal gland, liver, and heart and tissue- and enzyme-specific responses to lipopolysaccharide"],"prefix":"10.1016","volume":"722","author":[{"given":"Simona","family":"Moravcov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Spi\u0161sk\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominika","family":"Pa\u010desov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leona","family":"Hrubcov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneta","family":"Kubi\u0161tov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji\u0159\u00ed","family":"Novotn\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2693-2143","authenticated-orcid":false,"given":"Zdenka","family":"Bendov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.abb.2022.109213_bib1","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1146\/annurev-physiol-021909-135821","article-title":"The mammalian circadian timing system: organization and coordination of central and peripheral clocks","volume":"72","author":"Dibner","year":"2010","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.abb.2022.109213_bib2","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/nrg.2016.150","article-title":"Transcriptional architecture of the mammalian circadian clock","volume":"18","author":"Takahashi","year":"2017","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.abb.2022.109213_bib3","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0006-8993(79)90848-5","article-title":"Pineal N-acetyltransferase and hydroxyindole-O-methyl-transferase: control by the retinohypothalamic tract and the suprachiasmatic nucleus","volume":"174","author":"Klein","year":"1979","journal-title":"Brain Res."},{"key":"10.1016\/j.abb.2022.109213_bib4","first-page":"307","article-title":"The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland","volume":"52","author":"Klein","year":"1997","journal-title":"Recent Prog. Horm. Res."},{"key":"10.1016\/j.abb.2022.109213_bib5","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1080\/07420520500521962","article-title":"Rat and Syrian hamster: two models for the regulation of AANAT gene expression","volume":"23","author":"Simonneaux","year":"2006","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.abb.2022.109213_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines8120579","article-title":"Constant light in critical postnatal days affects circadian rhythms in locomotion and gene expression in the suprachiasmatic nucleus, retina, and pineal gland later in Life","volume":"8","author":"Kubi\u0161tov\u00e1","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.abb.2022.109213_bib7","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1046\/j.1471-4159.2003.01959.x","article-title":"Comparison of circadian expression of tryptophan hydroxylase isoform mRNAs in the rat pineal gland using real-time PCR","volume":"86","author":"Sugden","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.abb.2022.109213_bib8","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/BF00734813","article-title":"Circadian rhythm of tryptophan hydroxylase activity in chicken retina","volume":"11","author":"Thomas","year":"1991","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.abb.2022.109213_bib9","doi-asserted-by":"crossref","DOI":"10.1177\/1178646917691938","article-title":"Kynurenine pathway of tryptophan metabolism: regulatory and functional aspects","volume":"10","author":"Badawy","year":"2017","journal-title":"Int. J. Tryptophan Res."},{"key":"10.1016\/j.abb.2022.109213_bib10","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1111\/j.1471-4159.1993.tb03269.x","article-title":"Identification of tryptophan 2,3-dioxygenase RNA in rodent brain","volume":"60","author":"Haber","year":"1993","journal-title":"J. Neurochem."},{"key":"10.1016\/j.abb.2022.109213_bib11","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/0024-3205(91)90070-R","article-title":"Characterization of the L-tryptophan transport system in the liver of growing rats","volume":"49","author":"Saito","year":"1991","journal-title":"Life Sci."},{"key":"10.1016\/j.abb.2022.109213_bib12","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1042\/BSR20080085","article-title":"Substrate specificity and structure of human aminoadipate aminotransferase\/kynurenine aminotransferase II","volume":"28","author":"Han","year":"2008","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.abb.2022.109213_bib13","doi-asserted-by":"crossref","first-page":"946","DOI":"10.3390\/ijms17060946","article-title":"Kynurenine aminotransferase isozyme inhibitors: a Review","volume":"17","author":"Nematollahi","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.abb.2022.109213_bib14","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1756-6606-2-8","article-title":"Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice","volume":"2","author":"Kanai","year":"2009","journal-title":"Mol. Brain"},{"key":"10.1016\/j.abb.2022.109213_bib15","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1093\/alcalc\/agt028","article-title":"Characterization of functional polymorphisms and glucocorticoid-responsive elements in the promoter of TDO2, a candidate gene for ethanol-induced behavioural disorders","volume":"48","author":"Soichot","year":"2013","journal-title":"Alcohol Alcohol"},{"key":"10.1016\/j.abb.2022.109213_bib16","doi-asserted-by":"crossref","first-page":"4750","DOI":"10.1016\/S0021-9258(18)32486-4","article-title":"Transcriptional regulation of the tryptophan oxygenase gene in rat liver by glucocorticoids","volume":"258","author":"Danesch","year":"1983","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.abb.2022.109213_bib17","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaf9794","article-title":"Kynurenines: tryptophan's metabolites in exercise, inflammation, and mental health","author":"Cervenka","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.abb.2022.109213_bib18","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.bbi.2017.12.006","article-title":"Glia- and tissue-specific changes in the Kynurenine Pathway after treatment of mice with lipopolysaccharide and dexamethasone","volume":"69","author":"Dostal","year":"2018","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.abb.2022.109213_bib19","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1089\/107999003322277829","article-title":"Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha","volume":"23","author":"Robinson","year":"2003","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.abb.2022.109213_bib20","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s12974-016-0590-y","article-title":"Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge","volume":"13","author":"Parrott","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.abb.2022.109213_bib21","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/7215684","article-title":"Acute psychological stress modulates the expression of enzymes involved in the kynurenine pathway throughout corticolimbic circuits in adult male rats","author":"Vecchiarelli","year":"2016","journal-title":"Neural Plast."},{"key":"10.1016\/j.abb.2022.109213_bib22","doi-asserted-by":"crossref","first-page":"3700","DOI":"10.1016\/j.jmb.2019.12.044","article-title":"Molecular interactions between components of the circadian clock and the immune system","volume":"432","author":"Hergenhan","year":"2020","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.abb.2022.109213_bib23","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1126\/science.aah4967","article-title":"Circadian physiology of metabolism","volume":"354","author":"Panda","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.abb.2022.109213_bib24","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41398-020-0694-0","article-title":"Circadian rhythm disruption and mental health","volume":"10","author":"Walker","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.abb.2022.109213_bib25","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/s41380-019-0414-4","article-title":"The kynurenine pathway: a finger in every pie","volume":"25","author":"Savitz","year":"2020","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.abb.2022.109213_bib26","doi-asserted-by":"crossref","first-page":"620","DOI":"10.3181\/00379727-133-34530","article-title":"Daily variation in liver tryptophan, tryptophan pyrrolase, and tyrosine transaminase in rats fed ad libitum or single daily meals","volume":"133","author":"Fuller","year":"1970","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.abb.2022.109213_bib27","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/219619a0","article-title":"Circadian oscillation in rat liver tryptophan pyrrolase and its analysis by substrate and hormone induction","volume":"219","author":"Hardeland","year":"1968","journal-title":"Nature"},{"key":"10.1016\/j.abb.2022.109213_bib28","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1126\/science.153.3744.1642","article-title":"Circadian rhythm for tryptophan pyrrolase activity and its circulating substrate","volume":"153","author":"Rapoport","year":"1966","journal-title":"Science"},{"key":"10.1016\/j.abb.2022.109213_bib29","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1172\/JCI105785","article-title":"Circadian periodicity of tryptophan metabolism","volume":"47","author":"Rapoport","year":"1968","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.abb.2022.109213_bib30","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0003-9861(80)90185-X","article-title":"Regulation of indoleamine 2,3-dioxygenase activity in the small intestine and the epididymis of mice","volume":"203","author":"Yoshida","year":"1980","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.abb.2022.109213_bib31","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1196\/annals.1356.028","article-title":"Mechanisms regulating melatonin synthesis in the mammalian pineal organ","volume":"1057","author":"Schomerus","year":"2005","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.abb.2022.109213_bib32","first-page":"183","article-title":"TLR4 and CD14 receptors expressed in rat pineal gland trigger NFKB pathway","volume":"49","author":"da Silveira Cruz-Machado","year":"2010","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.abb.2022.109213_bib33","first-page":"1105","article-title":"The circadian rhythms of STAT3 in the rat pineal gland and its involvement in arylalkylamine-N-acetyltransferase regulation","volume":"11","author":"Moravcov\u00e1","year":"2021","journal-title":"Life (Basel)"},{"key":"10.1016\/j.abb.2022.109213_bib34","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.abb.2022.109213_bib35","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/nature744","article-title":"Extensive and divergent circadian gene expression in liver and heart","volume":"417","author":"Storch","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.abb.2022.109213_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0199405","article-title":"The day\/night difference in the circadian clock's response to acute lipopolysaccharide and the rhythmic Stat3 expression in the rat suprachiasmatic nucleus","volume":"13","author":"Moravcov\u00e1","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.abb.2022.109213_bib37","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/jnr.23673","article-title":"Identification of STAT3 and STAT5 proteins in the rat suprachiasmatic nucleus and the Day\/Night difference in astrocytic STAT3 phosphorylation in response to lipopolysaccharide","volume":"94","author":"Moravcov\u00e1","year":"2016","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.abb.2022.109213_bib38","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1002\/1521-4141(200108)31:8<2313::AID-IMMU2313>3.0.CO;2-S","article-title":"Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-gamma-independent mechanism","volume":"31","author":"Fujigaki","year":"2001","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.abb.2022.109213_bib39","doi-asserted-by":"crossref","first-page":"12884","DOI":"10.1523\/JNEUROSCI.4101-07.2007","article-title":"Characterization of the kynurenine pathway in human neurons","volume":"27","author":"Guillemin","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.abb.2022.109213_bib40","doi-asserted-by":"crossref","first-page":"4200","DOI":"10.1523\/JNEUROSCI.5032-08.2009","article-title":"Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin","volume":"29","author":"O'Connor","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.abb.2022.109213_bib41","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.brainres.2005.12.056","article-title":"Upregulation of the initiating step of the kynurenine pathway in postmortem anterior cingulate cortex from individuals with schizophrenia and bipolar disorder","volume":"1073\u20131074","author":"Miller","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.abb.2022.109213_bib42","doi-asserted-by":"crossref","first-page":"13216","DOI":"10.1074\/jbc.M706749200","article-title":"A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression","volume":"283","author":"Murphy","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.abb.2022.109213_bib43","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.brainres.2006.02.047","article-title":"Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies","volume":"1085","author":"Sakowski","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.abb.2022.109213_bib44","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1016\/S0006-2952(03)00556-2","article-title":"A unique central tryptophan hydroxylase isoform","volume":"66","author":"Walther","year":"2003","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.abb.2022.109213_bib45","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1111\/cas.14333","article-title":"Induction of tryptophan hydroxylase in the liver of s.c. tumor model of prostate cancer","volume":"111","author":"Hagiwara","year":"2020","journal-title":"Cancer Sci."},{"key":"10.1016\/j.abb.2022.109213_bib46","article-title":"Effect of daytime-restricted feeding in the daily variations of liver metabolism and blood transport of serotonin in rat","volume":"3","author":"Vald\u00e9s-Fuentes","year":"2015","journal-title":"Phys. Rep."},{"key":"10.1016\/j.abb.2022.109213_bib47","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1159\/000007590","article-title":"Differential distribution of serotonin and tryptophan hydroxylase in the human gastrointestinal tract","volume":"60","author":"Meyer","year":"1999","journal-title":"Digestion"},{"key":"10.1016\/j.abb.2022.109213_bib48","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2108\/zsj.15.345","article-title":"Molecular cloning and characterization of a cDNA encoding the retinal arylalkylamine N-acetyltransferase of the rainbow trout, Oncorhynchus mykiss","volume":"15","author":"Mizusawa","year":"1998","journal-title":"Jzoo"},{"key":"10.1016\/j.abb.2022.109213_bib49","doi-asserted-by":"crossref","first-page":"4305","DOI":"10.1096\/fj.201700097R","article-title":"Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR-200b down-regulation","volume":"31","author":"Wu","year":"2017","journal-title":"Faseb. J."},{"key":"10.1016\/j.abb.2022.109213_bib50","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.surge.2011.11.002","article-title":"Serotonin: a double-edged sword for the liver?","volume":"10","author":"Lesurtel","year":"2012","journal-title":"Surgeon"},{"key":"10.1016\/j.abb.2022.109213_bib51","article-title":"Effects of melatonin on liver injuries and diseases","volume":"18","author":"Zhang","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.abb.2022.109213_bib52","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.3109\/07420528.2010.496911","article-title":"Melatonin-synthesizing enzymes in pineal, retina, liver, and gut of the goldfish (Carassius): mRNA expression pattern and regulation of daily rhythms by lighting conditions","volume":"27","author":"Velarde","year":"2010","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.abb.2022.109213_bib53","doi-asserted-by":"crossref","first-page":"113693","DOI":"10.1016\/j.ygcen.2020.113693","article-title":"Gut melatonin: a potent candidate in the diversified journey of melatonin research","volume":"303","author":"Yasmin","year":"2021","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.abb.2022.109213_bib54","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1124\/jpet.108.140186","article-title":"Circadian variations in rat liver gene expression: relationships to drug actions","volume":"326","author":"Almon","year":"2008","journal-title":"J. Pharmacol. Exp. Therapeut."},{"key":"10.1016\/j.abb.2022.109213_bib55","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.cell.2014.06.050","article-title":"Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism","volume":"158","author":"Masri","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.abb.2022.109213_bib56","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1002\/j.2040-4603.2014.tb00576.x","article-title":"HPA axis-rhythms","volume":"4","author":"Spiga","year":"2014","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.abb.2022.109213_bib57","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/nature05767","article-title":"Transcriptional coactivator PGC-1\u03b1 integrates the mammalian clock and energy metabolism","volume":"447","author":"Liu","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.abb.2022.109213_bib58","doi-asserted-by":"crossref","first-page":"C836","DOI":"10.1152\/ajpcell.00053.2016","article-title":"Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans","volume":"310","author":"Schlittler","year":"2016","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.abb.2022.109213_bib59","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.02510","article-title":"MicroRNAs shape circadian hepatic gene expression on a transcriptome-wide scale","volume":"3","author":"Du","year":"2014","journal-title":"Elife"},{"key":"10.1016\/j.abb.2022.109213_bib60","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s13045-018-0600-x","article-title":"miR-153 suppresses Ido1 expression and enhances CAR T cell immunotherapy","volume":"11","author":"Huang","year":"2018","journal-title":"J. Hematol. Oncol."},{"key":"10.1016\/j.abb.2022.109213_bib61","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1111\/jnc.15222","article-title":"Prefrontal cortex miR-874-3p prevents lipopolysaccharide-induced depression-like behavior through inhibition of indoleamine 2,3-dioxygenase 1 expression in mice","volume":"157","author":"Suento","year":"2021","journal-title":"J. Neurochem."},{"key":"10.1016\/j.abb.2022.109213_bib62","doi-asserted-by":"crossref","first-page":"4642","DOI":"10.1038\/emboj.2011.322","article-title":"Temporal orchestration of circadian autophagy rhythm by C\/EBP\u03b2","volume":"30","author":"Ma","year":"2011","journal-title":"EMBO J."},{"key":"10.1016\/j.abb.2022.109213_bib63","doi-asserted-by":"crossref","first-page":"657","DOI":"10.3389\/fimmu.2020.00657","article-title":"Constitutive expression of the immunosuppressive tryptophan dioxygenase TDO2 in glioblastoma is driven by the transcription factor C\/EBP\u03b2","volume":"11","author":"Kudo","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.abb.2022.109213_bib64","doi-asserted-by":"crossref","first-page":"243","DOI":"10.3389\/fphys.2019.00243","article-title":"Liver CEBP\u03b2 modulates the kynurenine metabolism and mediates the motility for hypoxia-induced central fatigue in mice","volume":"10","author":"Yang","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.abb.2022.109213_bib65","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/s41419-020-03295-y","article-title":"Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia\/reperfusion injury","volume":"12","author":"Qiu","year":"2021","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.abb.2022.109213_bib66","doi-asserted-by":"crossref","first-page":"422","DOI":"10.3389\/fimmu.2016.00422","article-title":"Immunomodulatory factors galectin-9 and interferon-gamma synergize to induce expression of rate-limiting enzymes of the kynurenine pathway in the mouse Hippocampus","volume":"7","author":"Brooks","year":"2016","journal-title":"Front. Immunol."},{"key":"10.1016\/j.abb.2022.109213_bib67","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/1753425913481252","article-title":"Activation of indoleamine 2,3-dioxygenase by LPS in a porcine model","volume":"20","author":"Wirthgen","year":"2014","journal-title":"Innate Immun."},{"key":"10.1016\/j.abb.2022.109213_bib68","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2174\/138920007780362509","article-title":"The human indoleamine 2,3-dioxygenase gene and related human genes","volume":"8","author":"Murray","year":"2007","journal-title":"Curr. Drug Metabol."},{"key":"10.1016\/j.abb.2022.109213_bib69","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.biocel.2008.01.005","article-title":"Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway","volume":"41","author":"Ball","year":"2009","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.abb.2022.109213_bib70","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.gene.2007.04.010","article-title":"Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice","volume":"396","author":"Ball","year":"2007","journal-title":"Gene"},{"key":"10.1016\/j.abb.2022.109213_bib71","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.neulet.2008.06.007","article-title":"Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma?","volume":"441","author":"Connor","year":"2008","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.abb.2022.109213_bib72","first-page":"826","article-title":"The immune effects of TRYCATs (tryptophan catabolites along the Ido pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation","volume":"28","author":"Maes","year":"2007","journal-title":"Neuroendocrinol. Lett."},{"key":"10.1016\/j.abb.2022.109213_bib73","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/nm.2092","article-title":"Kynurenine is an endothelium-derived relaxing factor produced during inflammation","volume":"16","author":"Wang","year":"2010","journal-title":"Nat. Med."},{"key":"10.1016\/j.abb.2022.109213_bib74","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/QCO.0b013e32834536ce","article-title":"Lipopolysaccharide and sepsis-associated myocardial dysfunction","volume":"24","author":"Balija","year":"2011","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.abb.2022.109213_bib75","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1007\/s00018-017-2504-2","article-title":"Abnormal kynurenine pathway of tryptophan catabolism in cardiovascular diseases","volume":"74","author":"Song","year":"2017","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.abb.2022.109213_bib76","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3109\/07420521003769111","article-title":"Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver","volume":"27","author":"Yamamura","year":"2010","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.abb.2022.109213_bib77","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jss.2007.01.010","article-title":"Injection of LPS causes transient suppression of biological clock genes in rats","volume":"145","author":"Okada","year":"2008","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.abb.2022.109213_bib78","doi-asserted-by":"crossref","first-page":"12843","DOI":"10.1073\/pnas.0701466104","article-title":"TNF-alpha suppresses the expression of clock genes by interfering with E-box-mediated transcription","volume":"104","author":"Cavadini","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.abb.2022.109213_bib79","doi-asserted-by":"crossref","first-page":"715","DOI":"10.3109\/07420528.2012.682681","article-title":"Role of proinflammatory cytokines on lipopolysaccharide-induced phase shifts in locomotor activity circadian rhythm","volume":"29","author":"Leone","year":"2012","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.abb.2022.109213_bib80","doi-asserted-by":"crossref","first-page":"127395","DOI":"10.1016\/j.bmcl.2020.127395","article-title":"The transcriptional repressor REV-ERB as a novel target for disease","volume":"30","author":"Uriz-Huarte","year":"2020","journal-title":"Bioorg. Med. Chem. Lett"},{"key":"10.1016\/j.abb.2022.109213_bib81","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1038\/nrc2734","article-title":"STATs in cancer inflammation and immunity: a leading role for STAT3","volume":"9","author":"Yu","year":"2009","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.abb.2022.109213_bib82","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/bs.acc.2019.08.005","article-title":"Tryptophan in health and disease","volume":"95","author":"Comai","year":"2020","journal-title":"Adv. Clin. Chem."},{"key":"10.1016\/j.abb.2022.109213_bib83","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s12929-020-00671-w","article-title":"5-methoxytryptophan: an arsenal against vascular injury and inflammation","volume":"27","author":"Wu","year":"2020","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.abb.2022.109213_bib84","article-title":"Peripheral serotonin lacks effects on endothelial adhesion molecule expression in acute inflammation","author":"Mauler","year":"2021","journal-title":"J. Thromb. Haemostasis"}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986122000984?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986122000984?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T06:21:50Z","timestamp":1757744510000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986122000984"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":84,"alternative-id":["S0003986122000984"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2022.109213","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Circadian control of kynurenine pathway enzymes in the rat pineal gland, liver, and heart and tissue- and enzyme-specific responses to lipopolysaccharide","name":"articletitle","label":"Article Title"},{"value":"Archives of Biochemistry and Biophysics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abb.2022.109213","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109213"}}